{ "generated": "2026-08-16", "count": 388, "voice": "biohacker-expanded", "ranking_note": "Discussion volume only \u2014 not medical importance or efficacy.", "compounds": [ { "id": 1, "slug": "bpc-157", "name": "BPC-157", "aliases": [ "Body Protection Compound-157", "BPC157", "PL 14736", "BPC 157", "PL14736", "PL-10 (oral Bepecin trial code discussions)", "Bepecin (research designation)", "Stable gastric pentadecapeptide BPC 157", "Pentadeca arginate / PDA (arginate salt marketing name)", "Arg-BPC / BPC-157 arginate (oral-stability form talk)" ], "type": "Peptide", "category": "Healing & repair", "goals_use_cases": [ "recovery", "injury repair", "gut health", "joints & tendons", "soft-tissue healing", "inflammation (discussed)", "muscle strain recovery", "post-overuse repair", "GI lining support (discussed)", "performance continuity", "post-surgical soft-tissue talk", "NSAID-related gut complaint talk" ], "delivery_methods": [ "subcutaneous", "oral" ], "discussion_popularity": "High", "reach": "Mixed", "misspellings_search_terms": [ "bpc-157", "bpc 157", "bpc157", "Body Protection Compound-157", "PL 14736", "PL14736", "tendon pain", "achilles", "tennis elbow", "gut", "healing", "injury", "recovery", "wolverine", "pcac", "503a", "compounding", "fda approved", "nasal bpc", "site injection", "belly vs site", "nasal", "anhedonia", "site pin" ], "feel_search": [ "tendon pain", "achilles", "tennis elbow", "gut", "healing", "injury", "recovery", "wolverine", "nasal", "anhedonia", "site pin" ], "summary": "BPC-157 is a synthetic 15-amino-acid peptide discussed for tendon and injury recovery, stiffness and gut symptoms. Some users report less daily pain over several weeks.", "search_blob": "bpc-157 bpc-157 body protection compound-157 bpc157 pl 14736 bpc 157 pl14736 pl-10 (oral bepecin trial code discussions) bepecin (research designation) stable gastric pentadecapeptide bpc 157 pentadeca arginate / pda (arginate salt marketing name) arg-bpc / bpc-157 arginate (oral-stability form talk) bpc-157 bpc 157 bpc157 body protection compound-157 pl 14736 pl14736 tendon pain achilles tennis elbow gut healing injury recovery wolverine pcac 503a compounding fda approved nasal bpc site injection belly vs site nasal anhedonia site pin recovery injury repair gut health joints & tendons soft-tissue healing inflammation (discussed) muscle strain recovery post-overuse repair gi lining support (discussed) performance continuity post-surgical soft-tissue talk nsaid-related gut complaint talk tendon pain achilles tennis elbow gut healing injury recovery wolverine nasal anhedonia site pin bpc-157 is a synthetic 15-amino-acid peptide discussed for tendon and injury recovery, stiffness and gut symptoms. some users report less daily pain over several weeks. reports mix less shoulder pain with nausea, palpitations, feeling detached or stomach discomfort. self-rated relief is not proof of tissue healing. bpc-157 is a synthetic 15-amino-acid peptide discussed for tendon and injury recovery, stiffness and gut symptoms. users report multi-week drop in daily pain/irritation noise. common reports concern achilles, elbow and knee pain, and gut symptoms. july 2026 compounding-vote headlines are not \u201cfda approved.\u201d many logs also include tb-500 (wolverine), making bpc's contribution difficult to separate. healing & repair peptide mixed mixed \u2014 users debate injections near an injury versus the abdomen for whole-body or gut effects. mixed local systemic", "legal_class": null }, { "id": 2, "slug": "semaglutide", "name": "Semaglutide", "aliases": [ "Ozempic", "Wegovy", "Rybelsus", "sema", "Sema", "Semaglutide acetate (research/compounded discussions)", "Semaglutide sodium (research/compounded salt form \u2014 FDA concern)", "NN9535 (developmental designation, historical)", "GLP-1 RA / weekly GLP-1" ], "type": "Peptide", "category": "Metabolic / GLP-1 class", "goals_use_cases": [ "fat loss", "appetite control", "metabolic health", "glucose", "food noise reduction", "glucose / glycemic discussion", "weight management / obesity", "type 2 diabetes (approved context)", "cardiometabolic risk talk", "body recomposition (confounded by lean loss)", "diabetes-adjacent research interest", "microdosing / low-dose aesthetic or maintenance talk" ], "delivery_methods": [ "subcutaneous", "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "semaglutide", "Ozempic", "Wegovy", "Rybelsus", "Sema", "Semaglutide acetate (research/compounded discussions)", "food noise", "appetite", "nausea", "full fast", "fat loss", "compounding", "research use only", "alcohol", "muscle loss", "ozempic", "wegovy", "ozempic face" ], "feel_search": [ "food noise", "appetite", "nausea", "ozempic", "wegovy", "full fast", "fat loss", "compounding", "research use only", "alcohol", "muscle loss", "ozempic face" ], "summary": "Semaglutide is a long-acting GLP-1 analogue used in diabetes and weight-related medicines; brands, indications and oral/injection forms differ.", "search_blob": "semaglutide semaglutide ozempic wegovy rybelsus sema sema semaglutide acetate (research/compounded discussions) semaglutide sodium (research/compounded salt form \u2014 fda concern) nn9535 (developmental designation, historical) glp-1 ra / weekly glp-1 semaglutide ozempic wegovy rybelsus sema semaglutide acetate (research/compounded discussions) food noise appetite nausea full fast fat loss compounding research use only alcohol muscle loss ozempic wegovy ozempic face fat loss appetite control metabolic health glucose food noise reduction glucose / glycemic discussion weight management / obesity type 2 diabetes (approved context) cardiometabolic risk talk body recomposition (confounded by lean loss) diabetes-adjacent research interest microdosing / low-dose aesthetic or maintenance talk food noise appetite nausea ozempic wegovy full fast fat loss compounding research use only alcohol muscle loss ozempic face semaglutide is a long-acting glp-1 analogue used in diabetes and weight-related medicines; brands, indications and oral/injection forms differ. users describe quieter appetite with occasional hungry days; one long-term user still craved more food before the next shot. semaglutide is a glp-1 medicine people discuss for quieter appetite and fewer persistent thoughts about food. they describe appetite changes rather than a stimulant-like feeling. people discuss slow increases because stomach symptoms can worsen after a larger amount. common brand names in these discussions include ozempic and wegovy. metabolic / glp-1 class peptide systemic whole-body \u2014 appetite and stomach-emptying, not a local fat pin. systemic whole-body circulating", "legal_class": null }, { "id": 3, "slug": "tirzepatide", "name": "Tirzepatide", "aliases": [ "Mounjaro", "Zepbound", "tirz", "TZP", "LY3298176", "dual GIP/GLP-1 agonist", "twincretin (informal)" ], "type": "Peptide", "category": "Metabolic / GLP-1 class", "goals_use_cases": [ "fat loss", "appetite control", "metabolic health", "glucose", "appetite control / food-noise reduction", "glucose / HbA1c (T2D labeled context)", "weight management / obesity", "type 2 diabetes (approved context)", "obstructive sleep apnea (Zepbound labeled discussion)", "body recomposition (discussed; muscle-preservation focus)", "cardiometabolic risk markers (discussed)", "waist / visceral-fat talk" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "tirzepatide", "Mounjaro", "Zepbound", "tirz", "TZP", "LY3298176", "food noise", "appetite", "nausea", "fat loss", "compounding", "research use only", "alcohol", "split dose", "B12", "mounjaro", "zepbound" ], "feel_search": [ "food noise", "appetite", "nausea", "mounjaro", "zepbound", "fat loss", "compounding", "research use only", "alcohol", "split dose", "B12" ], "summary": "Tirzepatide is an injectable peptide activating GIP and GLP-1 receptors, used in diabetes and weight-related medicines.", "search_blob": "tirzepatide tirzepatide mounjaro zepbound tirz tzp ly3298176 dual gip/glp-1 agonist twincretin (informal) tirzepatide mounjaro zepbound tirz tzp ly3298176 food noise appetite nausea fat loss compounding research use only alcohol split dose b12 mounjaro zepbound fat loss appetite control metabolic health glucose appetite control / food-noise reduction glucose / hba1c (t2d labeled context) weight management / obesity type 2 diabetes (approved context) obstructive sleep apnea (zepbound labeled discussion) body recomposition (discussed; muscle-preservation focus) cardiometabolic risk markers (discussed) waist / visceral-fat talk food noise appetite nausea mounjaro zepbound fat loss compounding research use only alcohol split dose b12 tirzepatide is an injectable peptide activating gip and glp-1 receptors, used in diabetes and weight-related medicines. some users describe quieter food thoughts and easier satiety; others still feel hungry despite finding overeating uncomfortable. tirzepatide is a weekly medicine people discuss for appetite control. some report early reductions in hunger, portion size, snacking and thoughts about food. people compare weekly amounts and increases, often around stomach side effects. mounjaro and zepbound are its familiar brand names. metabolic / glp-1 class peptide systemic systemic \u2014 dual gip/glp-1 receptor agonist; whole-body appetite, delayed gastric emptying, insulin/glucagon balance, and glucose effects. systemic whole-body circulating", "legal_class": null }, { "id": 4, "slug": "retatrutide", "name": "Retatrutide", "aliases": [ "LY3437943", "reta", "triple agonist", "Reta", "Triple agonist", "Triple-G agonist", "GLP-3 (informal community nickname)", "GIP/GLP-1/glucagon triple agonist", "Lilly triple agonist" ], "type": "Peptide", "category": "Metabolic / GLP-1 class", "goals_use_cases": [ "fat loss", "appetite control", "metabolic health", "appetite control / food-noise reduction", "body recomposition (discussed; large absolute loss includes some lean mass)", "glycemic control (T2D trial context)", "liver fat / MASLD reduction (trial substudy)", "cardiometabolic markers (BP, lipids, waist)", "obesity research (investigational, not FDA-approved as of last research)", "knee OA pain and OSA secondary outcomes (Phase 3 program talk)", "lean-user microdose recomp (community, unvalidated)" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "retatrutide", "LY3437943", "Reta", "Triple agonist", "Triple-G agonist", "GLP-3 (informal community nickname)", "food noise", "fat loss", "nausea", "compounding", "research use only", "ratatouille", "alcohol", "muscle loss", "reta", "triple agonist" ], "feel_search": [ "food noise", "reta", "triple agonist", "fat loss", "nausea", "compounding", "research use only", "ratatouille", "alcohol", "muscle loss" ], "summary": "Retatrutide (LY3437943) is an investigational injectable peptide that activates GIP, GLP-1 and glucagon receptors for weight-related treatment.", "search_blob": "retatrutide retatrutide ly3437943 reta triple agonist reta triple agonist triple-g agonist glp-3 (informal community nickname) gip/glp-1/glucagon triple agonist lilly triple agonist retatrutide ly3437943 reta triple agonist triple-g agonist glp-3 (informal community nickname) food noise fat loss nausea compounding research use only ratatouille alcohol muscle loss reta triple agonist fat loss appetite control metabolic health appetite control / food-noise reduction body recomposition (discussed; large absolute loss includes some lean mass) glycemic control (t2d trial context) liver fat / masld reduction (trial substudy) cardiometabolic markers (bp, lipids, waist) obesity research (investigational, not fda-approved as of last research) knee oa pain and osa secondary outcomes (phase 3 program talk) lean-user microdose recomp (community, unvalidated) food noise reta triple agonist fat loss nausea compounding research use only ratatouille alcohol muscle loss retatrutide (ly3437943) is an investigational injectable peptide that activates gip, glp-1 and glucagon receptors for weight-related treatment. one user described markedly quieter food thoughts but strong hunger as the next injection approached; replies reported different appetite patterns. retatrutide is an investigational peptide discussed for fat loss. users report earlier fullness and reduced appetite, nausea or injection-day fatigue; some notice little change until amounts increase. discussions often describe increasing weekly amounts over time. the numbers come from trial groups and copied seller charts, not approved prescribing instructions. metabolic / glp-1 class peptide systemic whole-body appetite, glucose and energy-expenditure effects; not a local tissue injection. systemic whole-body circulating", "legal_class": null }, { "id": 5, "slug": "tb-500", "name": "TB-500", "aliases": [ "Thymosin Beta-4 fragment", "TB500", "TB-500 acetate", "Ac-LKKTETQ (analytical ID of many TB-500 products)", "T\u03b24 fragment (community shorthand)", "LKKTETQ / T\u03b24 (17\u201323) actin-binding region", "TB-4 frag (often misused label)" ], "type": "Peptide", "category": "Healing & repair", "goals_use_cases": [ "recovery", "injury repair", "flexibility", "soft-tissue", "soft-tissue healing", "joints & tendons", "inflammation (discussed)", "mobility", "performance continuity", "muscle soft-tissue", "systemic repair narrative", "post-strain / overuse bounce-back", "scar-tissue / flexibility talk (often mixed with full T\u03b24 claims)" ], "delivery_methods": [ "subcutaneous", "intramuscular" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "tb-500", "tb 500", "tb500", "TB-500 acetate", "Thymosin Beta-4 fragment", "Ac-LKKTETQ (analytical ID of many TB-500 products)", "flexibility", "mobility", "strain", "recovery", "stiff", "wolverine", "pcac", "503a", "compounding", "fda approved", "nasal tb-500", "tb4 nasal" ], "feel_search": [ "flexibility", "mobility", "strain", "recovery", "stiff", "wolverine" ], "summary": "TB-500 is a research peptide sold as a thymosin beta-4 fragment for injury-recovery interests; the label is often confused with full-length T\u03b24.", "search_blob": "tb-500 tb-500 thymosin beta-4 fragment tb500 tb-500 acetate ac-lkktetq (analytical id of many tb-500 products) t\u03b24 fragment (community shorthand) lkktetq / t\u03b24 (17\u201323) actin-binding region tb-4 frag (often misused label) tb-500 tb 500 tb500 tb-500 acetate thymosin beta-4 fragment ac-lkktetq (analytical id of many tb-500 products) flexibility mobility strain recovery stiff wolverine pcac 503a compounding fda approved nasal tb-500 tb4 nasal recovery injury repair flexibility soft-tissue soft-tissue healing joints & tendons inflammation (discussed) mobility performance continuity muscle soft-tissue systemic repair narrative post-strain / overuse bounce-back scar-tissue / flexibility talk (often mixed with full t\u03b24 claims) flexibility mobility strain recovery stiff wolverine tb-500 is a research peptide sold as a thymosin beta-4 fragment for injury-recovery interests; the label is often confused with full-length t\u03b24. reports range from less stiffness to headache and fatigue; combination use, rehabilitation and supplements make attribution difficult. tb-500 is a peptide people look up for recovery. people report faster multi-week recovery from strains, tweaks, and training overuse. discussion centers on flexibility and strains, often alongside bpc-157. milligram/microgram mix-ups, confusion between fragments and full t\u03b24, and compounding headlines mistaken for drug approval complicate these accounts. healing & repair peptide systemic whole-body recovery talk \u2014 most logs treat the injection site as \u201canywhere subq.\u201d systemic whole-body circulating", "legal_class": null }, { "id": 6, "slug": "cjc-1295-ipamorelin", "name": "CJC-1295 / Ipamorelin (blend discussion)", "aliases": [ "CJC Ipamorelin", "CJC/IPA", "CJC-1295 no DAC + Ipamorelin", "CJC IPA blend", "Mod GRF 1-29 + Ipamorelin", "CJC-1295/Ipamorelin", "CJC + Ipa", "CJC1295 Ipamorelin stack", "GHRH + GHS blend (CJC/IPA)", "CJC no DAC / IPA", "Mod GRF + Ipamorelin", "CJC IPA 5/5", "CJC-1295 Ipam" ], "type": "Peptide", "category": "Growth hormone axis", "goals_use_cases": [ "muscle growth", "recovery", "sleep", "fat loss", "performance", "muscle growth / lean mass (discussed)", "recovery / training readiness", "sleep quality / depth", "fat loss / recomp assist (discussed)", "performance continuity", "body composition", "anti-aging / wellness clinic use (discussed)", "IGF-1 support / lab proxy (discussed)", "skin / collagen / fullness talk", "joint / soft-tissue comfort (discussed)", "lean-mass support during GLP-1 cuts (discussed)", "TRT-adjacent men\u2019s-health layering (discussed)" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "cjc-1295-ipamorelin", "cjc 1295 ipamorelin", "cjc1295ipamorelin", "CJC-1295 / Ipamorelin (blend discussion)", "cjc-1295-/-ipamorelin-(blend-discussion)", "CJC Ipamorelin", "sleep", "deep sleep", "recovery", "hunger", "vivid dreams", "empty stomach", "compounding", "IGF-1", "carpal", "DAC", "reconstitution", "split dose", "research use only" ], "feel_search": [ "sleep", "deep sleep", "recovery", "hunger", "vivid dreams", "empty stomach", "compounding", "IGF-1", "carpal", "DAC", "reconstitution", "split dose", "research use only" ], "summary": "CJC/IPA usually means short-acting Mod GRF 1-29, called CJC no DAC, combined with ipamorelin to stimulate growth-hormone release.", "search_blob": "cjc-1295 / ipamorelin (blend discussion) cjc-1295-ipamorelin cjc ipamorelin cjc/ipa cjc-1295 no dac + ipamorelin cjc ipa blend mod grf 1-29 + ipamorelin cjc-1295/ipamorelin cjc + ipa cjc1295 ipamorelin stack ghrh + ghs blend (cjc/ipa) cjc no dac / ipa mod grf + ipamorelin cjc ipa 5/5 cjc-1295 ipam cjc-1295-ipamorelin cjc 1295 ipamorelin cjc1295ipamorelin cjc-1295 / ipamorelin (blend discussion) cjc-1295-/-ipamorelin-(blend-discussion) cjc ipamorelin sleep deep sleep recovery hunger vivid dreams empty stomach compounding igf-1 carpal dac reconstitution split dose research use only muscle growth recovery sleep fat loss performance muscle growth / lean mass (discussed) recovery / training readiness sleep quality / depth fat loss / recomp assist (discussed) performance continuity body composition anti-aging / wellness clinic use (discussed) igf-1 support / lab proxy (discussed) skin / collagen / fullness talk joint / soft-tissue comfort (discussed) lean-mass support during glp-1 cuts (discussed) trt-adjacent men\u2019s-health layering (discussed) sleep deep sleep recovery hunger vivid dreams empty stomach compounding igf-1 carpal dac reconstitution split dose research use only cjc/ipa usually means short-acting mod grf 1-29, called cjc no dac, combined with ipamorelin to stimulate growth-hormone release. one user reports poor sleep after a missed dose; another reports good sleep even on off-days. vivid dreams occur in some accounts, so dependence is not established. cjc/ipa is a peptide pairing people discuss for sleep and recovery. some report bedtime drowsiness, warmer sleep or vivid dreams after fasted pre-bed use; sleep quality varies. the pairing usually means no-dac cjc plus ipamorelin, supplied separately or in a premixed vial. nighttime use on an empty stomach is a common discussion pattern. growth hormone axis peptide systemic systemic \u2014 a ghrh analog plus a ghrelin-receptor agonist, discussed for whole-body sleep, recovery and composition rather than local tissue repair. systemic whole-body circulating", "legal_class": null }, { "id": 7, "slug": "ipamorelin", "name": "Ipamorelin", "aliases": [ "IPA", "NNC 26-0161", "Ipam", "NNC26-0161", "NNC 260161", "Aib-His-D-2-Nal-D-Phe-Lys-NH2", "Ipamorelin acetate", "Ipamorelin acetate salt", "selective GHRP", "third-generation GHRP (community label)" ], "type": "Peptide", "category": "Growth hormone axis", "goals_use_cases": [ "muscle growth", "recovery", "sleep", "anti-aging discussion", "muscle growth / lean mass (discussed)", "recovery / training continuity", "sleep depth and fall-asleep ease", "anti-aging / wellness clinic discussion", "body recomposition", "performance / work capacity feel", "fat loss adjacency (via GH/IGF talk, not a fat burner)", "injury-season recovery adjacency", "IGF-1 support / axis engagement (discussed)", "lean recomp without GHRP-6-level hunger", "selective GHRP alternative to GHRP-2 / GHRP-6 / hexarelin", "dual-pulse stack with GHRH (CJC no-DAC / Mod GRF)" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "ipamorelin", "IPA", "Ipam", "NNC 26-0161", "NNC26-0161", "NNC 260161", "sleep", "recovery", "hunger", "gh pulse", "empty stomach", "compounding", "IGF-1", "carpal", "reconstitution", "split dose", "research use only" ], "feel_search": [ "sleep", "recovery", "hunger", "gh pulse", "empty stomach", "compounding", "IGF-1", "carpal", "reconstitution", "split dose", "research use only" ], "summary": "Ipamorelin is a synthetic peptide that stimulates growth-hormone release through the ghrelin receptor, discussed for sleep and recovery.", "search_blob": "ipamorelin ipamorelin ipa nnc 26-0161 ipam nnc26-0161 nnc 260161 aib-his-d-2-nal-d-phe-lys-nh2 ipamorelin acetate ipamorelin acetate salt selective ghrp third-generation ghrp (community label) ipamorelin ipa ipam nnc 26-0161 nnc26-0161 nnc 260161 sleep recovery hunger gh pulse empty stomach compounding igf-1 carpal reconstitution split dose research use only muscle growth recovery sleep anti-aging discussion muscle growth / lean mass (discussed) recovery / training continuity sleep depth and fall-asleep ease anti-aging / wellness clinic discussion body recomposition performance / work capacity feel fat loss adjacency (via gh/igf talk, not a fat burner) injury-season recovery adjacency igf-1 support / axis engagement (discussed) lean recomp without ghrp-6-level hunger selective ghrp alternative to ghrp-2 / ghrp-6 / hexarelin dual-pulse stack with ghrh (cjc no-dac / mod grf) sleep recovery hunger gh pulse empty stomach compounding igf-1 carpal reconstitution split dose research use only ipamorelin is a synthetic peptide that stimulates growth-hormone release through the ghrelin receptor, discussed for sleep and recovery. standalone accounts vary: one user noticed deeper sleep within days, another no change after two weeks, and another fatigue and increased appetite. a hormone-release effect need not produce a noticeable feeling. ipamorelin is a peptide people discuss for sleep and recovery, often combined with a ghrh analog. solo accounts include better sleep, no change and unwanted effects. users often compare its hunger and cortisol reports with older ghrps. bedtime injections are a common discussion pattern, not an established sleep treatment. growth hormone axis peptide systemic systemic ghrelin-receptor agonist discussed for gh pulses, sleep and recovery; not a targeted joint treatment. systemic whole-body circulating", "legal_class": null }, { "id": 8, "slug": "cjc-1295", "name": "CJC-1295", "aliases": [ "CJC-1295 with DAC", "CJC-1295 no DAC", "Mod GRF adjacency", "CJC-1295 without DAC", "Mod GRF 1-29", "Modified GRF 1-29", "DAC:GRF", "DAC:GRF (ConjuChem)", "CJC1295", "CJC 1295", "CJC-1295 DAC", "tetrasubstituted GRF 1-29" ], "type": "Peptide", "category": "Growth hormone axis", "goals_use_cases": [ "muscle growth", "recovery", "fat loss", "sleep", "performance", "body recomposition", "anti-aging (discussed)", "IGF-1 support (discussed)", "lean mass preservation", "skin / recovery adjacency" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "cjc-1295", "cjc 1295", "cjc1295", "CJC-1295 with DAC", "CJC-1295 no DAC", "CJC-1295 without DAC", "sleep", "water retention", "recovery", "empty stomach", "compounding", "IGF-1", "carpal", "DAC", "no-DAC", "reconstitution", "split dose" ], "feel_search": [ "sleep", "water retention", "recovery", "empty stomach", "compounding", "IGF-1", "carpal", "DAC", "no-DAC", "reconstitution", "split dose" ], "summary": "CJC-1295 is a growth-hormone-releasing-hormone analogue; the name is also used for no-DAC Mod GRF 1-29, a different short-acting product.", "search_blob": "cjc-1295 cjc-1295 cjc-1295 with dac cjc-1295 no dac mod grf adjacency cjc-1295 without dac mod grf 1-29 modified grf 1-29 dac:grf dac:grf (conjuchem) cjc1295 cjc 1295 cjc-1295 dac tetrasubstituted grf 1-29 cjc-1295 cjc 1295 cjc1295 cjc-1295 with dac cjc-1295 no dac cjc-1295 without dac sleep water retention recovery empty stomach compounding igf-1 carpal dac no-dac reconstitution split dose muscle growth recovery fat loss sleep performance body recomposition anti-aging (discussed) igf-1 support (discussed) lean mass preservation skin / recovery adjacency sleep water retention recovery empty stomach compounding igf-1 carpal dac no-dac reconstitution split dose cjc-1295 is a growth-hormone-releasing-hormone analogue; the name is also used for no-dac mod grf 1-29, a different short-acting product. a user adding no-dac cjc to ipamorelin describes a head rush within minutes. that immediate feeling does not establish muscle growth or long-term benefit. people discuss cjc-1295 for sleep, training recovery and body composition. the name is used for distinct dac and no-dac products, often combined with ipamorelin. sleep and vivid-dream reports appear early in no-dac discussions. dac accounts more often emphasize swelling and changes over weeks; neither dreams nor a flush verifies the product. growth hormone axis peptide systemic systemic \u2014 raises circulating gh/igf-1 via pituitary ghrh-receptor stimulation; not a local inject-site healing peptide. systemic whole-body circulating", "legal_class": null }, { "id": 9, "slug": "mk-677", "name": "MK-677", "aliases": [ "Ibutamoren", "Ibutamoren mesylate", "Nutrobal", "MK-0677", "MK0677", "L-163,191", "LUM-201", "Oratrope (former tentative brand)", "MK677", "MK 677" ], "type": "Non-peptide", "category": "Growth hormone axis", "goals_use_cases": [ "muscle growth", "sleep", "appetite", "recovery", "bone discussion", "muscle growth / lean mass (discussed; water + FFM mix)", "sleep quality (slow-wave / REM \u2014 trial-anchored)", "appetite / hard-gainer bulk", "recovery / training continuity", "IGF-1 elevation (discussed / lab-tracked)", "anti-catabolism during deficit (Murphy nitrogen talk)", "body recomposition (discussed; confounded by calories + water)", "bone turnover / density discussion (older-adult / osteoporosis trials)", "oral GH-axis alternative to injectables", "skin / fullness look (anecdotal)", "performance continuity (non-tested athletes \u2014 WADA banned)", "pediatric GHD research (LUM-201 program \u2014 separate clinical path)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "mk-677", "mk 677", "mk677", "Ibutamoren", "Ibutamoren mesylate", "MK-0677", "hunger", "sleep", "water retention", "bloated", "IGF-1", "glucose", "compounding", "research chemical", "ibutamoren" ], "feel_search": [ "hunger", "sleep", "water retention", "bloated", "ibutamoren", "IGF-1", "glucose", "compounding", "research chemical" ], "summary": "MK-677 (ibutamoren) is an oral ghrelin-receptor agonist that stimulates growth hormone; people seek appetite, sleep and fullness effects.", "search_blob": "mk-677 mk-677 ibutamoren ibutamoren mesylate nutrobal mk-0677 mk0677 l-163,191 lum-201 oratrope (former tentative brand) mk677 mk 677 mk-677 mk 677 mk677 ibutamoren ibutamoren mesylate mk-0677 hunger sleep water retention bloated igf-1 glucose compounding research chemical ibutamoren muscle growth sleep appetite recovery bone discussion muscle growth / lean mass (discussed; water + ffm mix) sleep quality (slow-wave / rem \u2014 trial-anchored) appetite / hard-gainer bulk recovery / training continuity igf-1 elevation (discussed / lab-tracked) anti-catabolism during deficit (murphy nitrogen talk) body recomposition (discussed; confounded by calories + water) bone turnover / density discussion (older-adult / osteoporosis trials) oral gh-axis alternative to injectables skin / fullness look (anecdotal) performance continuity (non-tested athletes \u2014 wada banned) pediatric ghd research (lum-201 program \u2014 separate clinical path) hunger sleep water retention bloated ibutamoren igf-1 glucose compounding research chemical mk-677 (ibutamoren) is an oral ghrelin-receptor agonist that stimulates growth hormone; people seek appetite, sleep and fullness effects. hunger and sleep changes are often noticed early. some report deeper sleep; others describe grogginess, water retention or tingling, and the strength of the effect varies. mk-677 is an oral compound people discuss for appetite, sleep and muscle-related goals. some report strong hunger and deeper sleep during nights 1\u201314; others notice little change or worse sleep. increased hunger can make a calorie deficit harder to sustain. water retention and fasting glucose recur in the discussion; community charts often repeat the 25 mg study amount. growth hormone axis non-peptide systemic systemic \u2014 oral non-peptide ghrelin-receptor (ghs-r1a) agonist / gh secretagogue; whole-body gh pulses and circulating igf-1, not local site targeting. systemic whole-body circulating", "legal_class": null }, { "id": 10, "slug": "ghk-cu", "name": "GHK-Cu", "aliases": [ "Copper peptide", "GHK copper", "glycyl-L-histidyl-L-lysine copper", "GHK-Cu copper tripeptide", "copper tripeptide-1 (cosmetic INCI contexts)", "Gly-His-Lys-Cu", "copper tripeptide-1" ], "type": "Peptide", "category": "Skin, hair & tissue remodeling", "goals_use_cases": [ "skin/hair", "recovery", "anti-aging discussion", "wound narratives", "collagen / firmness talk", "aesthetic remodeling", "longevity discussion", "scar / texture narratives", "post-procedure recovery talk", "Glow / KLOW stack component" ], "delivery_methods": [ "topical", "subcutaneous", "microneedling adjacency" ], "discussion_popularity": "High", "reach": "Mixed", "misspellings_search_terms": [ "ghk-cu", "ghk cu", "ghkcu", "Copper peptide", "GHK copper", "glycyl-L-histidyl-L-lysine copper", "skin", "hair", "wrinkles", "sting", "glow", "pcac", "503a", "compounding", "copper uglies", "after shower", "injectable ghk", "blue sting" ], "feel_search": [ "skin", "hair", "wrinkles", "sting", "glow", "copper uglies", "blue sting", "after shower" ], "summary": "GHK-Cu is a copper-binding peptide used in skin products and discussed in injection logs for skin and hair changes.", "search_blob": "ghk-cu ghk-cu copper peptide ghk copper glycyl-l-histidyl-l-lysine copper ghk-cu copper tripeptide copper tripeptide-1 (cosmetic inci contexts) gly-his-lys-cu copper tripeptide-1 ghk-cu ghk cu ghkcu copper peptide ghk copper glycyl-l-histidyl-l-lysine copper skin hair wrinkles sting glow pcac 503a compounding copper uglies after shower injectable ghk blue sting skin/hair recovery anti-aging discussion wound narratives collagen / firmness talk aesthetic remodeling longevity discussion scar / texture narratives post-procedure recovery talk glow / klow stack component skin hair wrinkles sting glow copper uglies blue sting after shower ghk-cu is a copper-binding peptide used in skin products and discussed in injection logs for skin and hair changes. ghk-cu is a copper-binding peptide discussed for firmer, smoother skin and less visible fine lines. users often compare photos at 8\u201312 weeks. injection accounts often mention stinging. visible skin changes are discussed over weeks. topical routines and injections are separate; ghk-cu was not part of the july 2026 bpc/tb compounding vote. skin, hair & tissue remodeling peptide mixed mixed \u2014 topical stays on skin/scalp; injectable charts treat it as whole-body remodeling. mixed local systemic", "legal_class": null }, { "id": 11, "slug": "melanotan-ii", "name": "Melanotan II", "aliases": [ "MT2", "MT-II", "Melanotan 2", "Melanotan-II", "MT-2", "MT II", "Barbie drug", "tan jab", "Ac-Nle-c[Asp-His-D-Phe-Arg-Trp-Lys]-NH2", "Ac-Nle4-Asp5-His6-D-Phe7-Arg8-Trp9-Lys10-\u03b1-MSH4-10-NH2" ], "type": "Peptide", "category": "Tanning & melanocortin", "goals_use_cases": [ "skin/hair", "libido", "appetite (discussed)", "tanning / pigmentation", "sunless / UV-assisted bronze", "nasal tanning spray interest", "libido / sexual arousal (discussed)", "erectile response (historical clinical discussion)", "appetite suppression (discussed)", "aesthetic bodybuilding / gym culture tan", "competition prep / stage color (discussed)", "photoprotection narrative (discussed, not proven protection)", "pre-vacation / seasonal tan runs" ], "delivery_methods": [ "subcutaneous", "nasal" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "melanotan-ii", "melanotan ii", "melanotanii", "MT2", "MT-II", "Melanotan 2", "tan", "nausea", "libido", "freckles", "barbie", "loading", "pt-141" ], "feel_search": [ "tan", "nausea", "libido", "freckles", "barbie", "loading", "pt-141" ], "summary": "Melanotan II is an experimental cyclic alpha-MSH analog used in tanning culture, with pigmentation, appetite and sexual-effect discussion.", "search_blob": "melanotan ii melanotan-ii mt2 mt-ii melanotan 2 melanotan-ii mt-2 mt ii barbie drug tan jab ac-nle-c[asp-his-d-phe-arg-trp-lys]-nh2 ac-nle4-asp5-his6-d-phe7-arg8-trp9-lys10-\u03b1-msh4-10-nh2 melanotan-ii melanotan ii melanotanii mt2 mt-ii melanotan 2 tan nausea libido freckles barbie loading pt-141 skin/hair libido appetite (discussed) tanning / pigmentation sunless / uv-assisted bronze nasal tanning spray interest libido / sexual arousal (discussed) erectile response (historical clinical discussion) appetite suppression (discussed) aesthetic bodybuilding / gym culture tan competition prep / stage color (discussed) photoprotection narrative (discussed, not proven protection) pre-vacation / seasonal tan runs tan nausea libido freckles barbie loading pt-141 melanotan ii is an experimental cyclic alpha-msh analog used in tanning culture, with pigmentation, appetite and sexual-effect discussion. reports include flushing and prolonged spontaneous erections as well as gradual pigment changes. one three-week tanning account said it felt side-effect-free but also described new freckles and sunbed use. melanotan ii is a peptide discussed for tanning. some people report deeper color with less uv exposure, but skin type, sun habits and unverified product contents make those accounts difficult to compare. freckles and moles may darken before the desired tan develops. nausea, uneven pigmentation and unwanted sexual effects are recurring reasons people stop. tanning & melanocortin peptide systemic systemic melanocortin agonist discussed for pigmentation, appetite and arousal; community products are unapproved injections or nasal sprays. systemic whole-body circulating", "legal_class": null }, { "id": 12, "slug": "pt-141", "name": "PT-141", "aliases": [ "Bremelanotide", "Vyleesi", "PT141", "PT 141", "Bremelanotide acetate", "BMT", "Bremelanotide injection" ], "type": "Peptide", "category": "Libido & melanocortin", "goals_use_cases": [ "libido", "sexual function", "libido / sexual desire (central)", "sexual function / arousal signaling", "HSDD \u2014 FDA-approved Vyleesi context (acquired, generalized; premenopausal women)", "desire / mental arousal (CNS melanocortin, not genital vasodilator)", "ED and PDE5 non-responders (historical IN trial + off-label clinic discussion)", "low desire in men (off-label clinic and forum talk \u2014 not FDA-indicated)", "psychogenic / performance-anxiety-adjacent desire talk", "PDE5 incomplete responders seeking \u2018want\u2019 + hardness (stack discussion)", "CNS sexual signaling research (MC4R/MC3R emphasis)", "as-needed PRN date-night pharmacology (not daily hormone replacement)" ], "delivery_methods": [ "subcutaneous", "nasal" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "pt-141", "pt 141", "pt141", "Bremelanotide", "Vyleesi", "Bremelanotide acetate", "libido", "desire", "nausea", "sex", "vyleesi", "zofran", "melanotan" ], "feel_search": [ "libido", "desire", "nausea", "vyleesi", "sex", "zofran", "melanotan" ], "summary": "PT-141, or bremelanotide, is a synthetic melanocortin-receptor peptide discussed for sexual desire; the medical product is an injection.", "search_blob": "pt-141 pt-141 bremelanotide vyleesi pt141 pt 141 bremelanotide acetate bmt bremelanotide injection pt-141 pt 141 pt141 bremelanotide vyleesi bremelanotide acetate libido desire nausea sex vyleesi zofran melanotan libido sexual function libido / sexual desire (central) sexual function / arousal signaling hsdd \u2014 fda-approved vyleesi context (acquired, generalized; premenopausal women) desire / mental arousal (cns melanocortin, not genital vasodilator) ed and pde5 non-responders (historical in trial + off-label clinic discussion) low desire in men (off-label clinic and forum talk \u2014 not fda-indicated) psychogenic / performance-anxiety-adjacent desire talk pde5 incomplete responders seeking \u2018want\u2019 + hardness (stack discussion) cns sexual signaling research (mc4r/mc3r emphasis) as-needed prn date-night pharmacology (not daily hormone replacement) libido desire nausea vyleesi sex zofran melanotan pt-141, or bremelanotide, is a synthetic melanocortin-receptor peptide discussed for sexual desire; the medical product is an injection. reports range from flushing without the desired effect to strong sexual response or severe nausea; one couple reported very different reactions. pt-141 is a peptide people discuss for libido. accounts describe clear responses, no benefit or different results across spaced uses; increasing the amount does not ensure benefit. nausea is a prominent complaint. the medical product uses 1.75 mg; some community accounts describe lower first exposures. libido & melanocortin peptide systemic systemic cns melanocortin agonist; desire/arousal signaling is central, while pigmentation and blood-pressure effects are systemic. systemic whole-body circulating", "legal_class": null }, { "id": 13, "slug": "aod-9604", "name": "AOD-9604", "aliases": [ "AOD 9604", "hGH Fragment 176-191 related marketing", "lipolytic fragment peptide", "AOD9604", "Tyr-hGH177-191", "Tyr-hGH 177-191", "Anti-Obesity Drug 9604", "hexadecapeptide 177-191", "C-terminal hGH fragment analog", "sh-Oligopeptide-74 (INCI-style naming in some safety write-ups)" ], "type": "Peptide", "category": "Metabolic / fat-loss peptides", "goals_use_cases": [ "fat loss", "body recomposition", "lipolysis support (discussed)", "lipogenesis inhibition (preclinical claim)", "abdominal / stubborn fat reduction (discussed)", "GH-like fat metabolism without IGF-1 rise (claimed)", "metabolic research", "cutting phase adjunct (community)", "performance continuity while leaning", "joint / cartilage research interest (animal IA data)", "GLP-1 stack polish without more appetite suppression (community)", "appetite-neutral fat-path adjunct vs satiety drugs (community framing)" ], "delivery_methods": [ "subcutaneous", "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "aod-9604", "aod 9604", "aod9604", "Tyr-hGH177-191", "Tyr-hGH 177-191", "hGH Fragment 176-191 related marketing", "stubborn fat", "waist", "fasted", "cut", "disappointed", "gel" ], "feel_search": [ "stubborn fat", "waist", "fasted", "cut", "disappointed", "gel" ], "summary": "AOD-9604 is a modified growth-hormone fragment investigated for fat loss, distinct from full growth hormone.", "search_blob": "aod-9604 aod-9604 aod 9604 hgh fragment 176-191 related marketing lipolytic fragment peptide aod9604 tyr-hgh177-191 tyr-hgh 177-191 anti-obesity drug 9604 hexadecapeptide 177-191 c-terminal hgh fragment analog sh-oligopeptide-74 (inci-style naming in some safety write-ups) aod-9604 aod 9604 aod9604 tyr-hgh177-191 tyr-hgh 177-191 hgh fragment 176-191 related marketing stubborn fat waist fasted cut disappointed gel fat loss body recomposition lipolysis support (discussed) lipogenesis inhibition (preclinical claim) abdominal / stubborn fat reduction (discussed) gh-like fat metabolism without igf-1 rise (claimed) metabolic research cutting phase adjunct (community) performance continuity while leaning joint / cartilage research interest (animal ia data) glp-1 stack polish without more appetite suppression (community) appetite-neutral fat-path adjunct vs satiety drugs (community framing) stubborn fat waist fasted cut disappointed gel aod-9604 is a modified growth-hormone fragment investigated for fat loss, distinct from full growth hormone. reports conflict: one person saw no change after seven weeks alongside ozempic; others claim waist changes while also using glp-1 drugs, dieting or training. aod-9604 is a peptide discussed for fat loss. some users report modest waist changes alongside diet and training; others notice no change. people often report morning injections while fasted. those routines do not establish a fasting advantage or targeted waist-fat reduction. metabolic / fat-loss peptides peptide systemic systemic fat-loss fragment claims, usually subq in community reports; not proven spot reduction or equivalent to oral trial dosing. systemic whole-body circulating", "legal_class": null }, { "id": 15, "slug": "tesamorelin", "name": "Tesamorelin", "aliases": [ "Egrifta", "TH9507", "Egrifta SV", "Egrifta WR", "TH-9507", "Tesamorelin acetate", "GHRH analog (trans-3-hexenoyl)" ], "type": "Peptide", "category": "Growth hormone axis", "goals_use_cases": [ "fat loss", "visceral fat discussion", "muscle preservation", "body recomposition", "metabolic health (discussed)", "liver fat / NAFLD adjacency (HIV trial data)", "HIV lipodystrophy context", "IGF-1 support (discussed)", "waist / midsection aesthetics", "GH-axis alternative to exogenous HGH" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "tesamorelin", "Egrifta", "Egrifta SV", "Egrifta WR", "TH9507", "TH-9507", "belly fat", "visceral fat", "vat", "water retention", "itch", "hives", "pinchable", "compounding", "research use only" ], "feel_search": [ "belly fat", "visceral fat", "vat", "water retention", "itch", "hives", "pinchable", "compounding", "research use only" ], "summary": "Tesamorelin is a synthetic GHRH analogue that stimulates pituitary growth-hormone release, discussed for visceral-fat reduction.", "search_blob": "tesamorelin tesamorelin egrifta th9507 egrifta sv egrifta wr th-9507 tesamorelin acetate ghrh analog (trans-3-hexenoyl) tesamorelin egrifta egrifta sv egrifta wr th9507 th-9507 belly fat visceral fat vat water retention itch hives pinchable compounding research use only fat loss visceral fat discussion muscle preservation body recomposition metabolic health (discussed) liver fat / nafld adjacency (hiv trial data) hiv lipodystrophy context igf-1 support (discussed) waist / midsection aesthetics gh-axis alternative to exogenous hgh belly fat visceral fat vat water retention itch hives pinchable compounding research use only tesamorelin is a synthetic ghrh analogue that stimulates pituitary growth-hormone release, discussed for visceral-fat reduction. several commenters reported fragmented sleep; one also mentioned palpitations, despite expecting sleep to improve. tesamorelin is a growth-hormone-releasing peptide discussed for deep abdominal fat. the hiv trials measured visceral fat on scans; general weight-loss accounts are a different context. community accounts discuss 1\u20132 mg sc daily. the original trial product used 2 mg; current sv uses 1.4 mg and wr 1.28 mg. these formulations are not interchangeable. growth hormone axis peptide systemic whole-body gh-axis \u2014 not a local fat-dissolve pin. systemic whole-body circulating", "legal_class": null }, { "id": 16, "slug": "sermorelin", "name": "Sermorelin", "aliases": [ "GHRH 1-29", "GRF 1-29", "Sermorelin acetate", "GHRH (1-29)", "GHRH (1-29) NH2", "GRF 1\u201329", "GRF 1-29 NH2", "Geref (historical brand)", "Geref Diagnostic (historical brand)", "Sermorelin acetate injection" ], "type": "Peptide", "category": "Growth hormone axis", "goals_use_cases": [ "anti-aging discussion", "sleep", "recovery", "muscle growth", "body composition", "IGF-1 support (discussed)", "performance continuity", "longevity clinic protocols", "pituitary GH stimulation (discussed)", "lean recomp (discussed)", "skin thickness / wellness talk", "age-related GH decline discussion" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "sermorelin", "Sermorelin acetate", "GHRH 1-29", "GHRH (1-29)", "GHRH (1-29) NH2", "GRF 1-29", "sleep", "anti-aging", "recovery", "empty stomach", "compounding", "IGF-1", "carpal", "Geref", "split dose" ], "feel_search": [ "sleep", "anti-aging", "recovery", "empty stomach", "compounding", "IGF-1", "carpal", "Geref", "split dose" ], "summary": "Sermorelin is a synthetic 29-amino-acid fragment of growth-hormone-releasing hormone (GHRH), used to stimulate pituitary GH release.", "search_blob": "sermorelin sermorelin ghrh 1-29 grf 1-29 sermorelin acetate ghrh (1-29) ghrh (1-29) nh2 grf 1\u201329 grf 1-29 nh2 geref (historical brand) geref diagnostic (historical brand) sermorelin acetate injection sermorelin sermorelin acetate ghrh 1-29 ghrh (1-29) ghrh (1-29) nh2 grf 1-29 sleep anti-aging recovery empty stomach compounding igf-1 carpal geref split dose anti-aging discussion sleep recovery muscle growth body composition igf-1 support (discussed) performance continuity longevity clinic protocols pituitary gh stimulation (discussed) lean recomp (discussed) skin thickness / wellness talk age-related gh decline discussion sleep anti-aging recovery empty stomach compounding igf-1 carpal geref split dose sermorelin is a synthetic 29-amino-acid fragment of growth-hormone-releasing hormone (ghrh), used to stimulate pituitary gh release. one user described vivid dreams and better recovery; another said sleep worsened and improved during a break. sermorelin is a peptide people discuss for sleep and recovery; historical geref products contained sermorelin acetate. reports include better sleep, no improvement and more wakefulness. clinic wellness discussions often feature sermorelin. hunger is less prominent in these accounts than in mk-677 discussion. growth hormone axis peptide systemic systemic \u2014 short-acting ghrh(1-29) fragment that pulses pituitary gh release; downstream igf-1 and whole-body recovery/sleep/body-comp effects. systemic whole-body circulating", "legal_class": null }, { "id": 17, "slug": "igf-1-lr3", "name": "IGF-1 LR3", "aliases": [ "Long R3 IGF-1", "IGF1 LR3", "IGF-1", "Long Arg3 IGF-1", "Long-R3-IGF-I", "LONG\u00ae R\u00b3 IGF-I (cell-culture reagent class)", "IGF-1 Long R3", "LR3 IGF-1", "LR3-IGF-1", "Long arginine 3-IGF-1" ], "type": "Peptide", "category": "Growth factors", "goals_use_cases": [ "muscle growth", "performance", "recovery", "muscle growth / hypertrophy (discussed)", "recovery / training continuity (discussed)", "body recomposition (discussed)", "site-enhancement / regional fullness discussion", "anti-catabolism (discussed)", "nutrient partitioning (discussed)", "satellite-cell / hyperplasia talk (community + preclinical framing)", "GH-axis \u201cdirect receptor\u201d alternative to HGH or secretagogues", "cell-culture / research-reagent context (industrial LONG R3 IGF-I)" ], "delivery_methods": [ "intramuscular", "subcutaneous" ], "discussion_popularity": "High", "reach": "Mixed", "misspellings_search_terms": [ "igf-1-lr3", "igf 1 lr3", "igf1lr3", "IGF-1 LR3", "Long R3 IGF-1", "Long Arg3 IGF-1", "pumps", "hypoglycemia", "shaky", "size", "fullness", "with food", "compounding", "IGF-1", "acetic acid", "glucose" ], "feel_search": [ "pumps", "hypoglycemia", "shaky", "size", "fullness", "with food", "compounding", "IGF-1", "acetic acid", "glucose" ], "summary": "IGF-1 LR3 is a modified IGF-1 research peptide, discussed for muscle fullness and growth; it is distinct from HGH and from IGF-1 DES.", "search_blob": "igf-1 lr3 igf-1-lr3 long r3 igf-1 igf1 lr3 igf-1 long arg3 igf-1 long-r3-igf-i long\u00ae r\u00b3 igf-i (cell-culture reagent class) igf-1 long r3 lr3 igf-1 lr3-igf-1 long arginine 3-igf-1 igf-1-lr3 igf 1 lr3 igf1lr3 igf-1 lr3 long r3 igf-1 long arg3 igf-1 pumps hypoglycemia shaky size fullness with food compounding igf-1 acetic acid glucose muscle growth performance recovery muscle growth / hypertrophy (discussed) recovery / training continuity (discussed) body recomposition (discussed) site-enhancement / regional fullness discussion anti-catabolism (discussed) nutrient partitioning (discussed) satellite-cell / hyperplasia talk (community + preclinical framing) gh-axis \u201cdirect receptor\u201d alternative to hgh or secretagogues cell-culture / research-reagent context (industrial long r3 igf-i) pumps hypoglycemia shaky size fullness with food compounding igf-1 acetic acid glucose igf-1 lr3 is a modified igf-1 research peptide, discussed for muscle fullness and growth; it is distinct from hgh and from igf-1 des. one six-week report describes modest early pumps, later endurance and fullness, plus water retention, sore hands and tingling. diet, training and tesofensine were part of the same period. igf-1 lr3 is a research peptide discussed for muscle growth. some users report fuller muscles or better recovery over weeks; others notice no benefit. discussion repeatedly raises low-blood-sugar concerns and food timing. forum routines do not establish safety. growth factors peptide mixed mixed \u2014 subq is the systemic forum default; im site use is debated, and no human lr3 half-life establishes long or local exposure. mixed local systemic", "legal_class": null }, { "id": 18, "slug": "epitalon", "name": "Epitalon", "aliases": [ "Epithalon", "Epithalone", "AEDG peptide", "AEDG", "Ala-Glu-Asp-Gly", "AlaGluAspGly", "Epithalamin (related pineal extract; not identical)", "Epithalamine (spelling variant of the extract)", "Khavinson pineal tetrapeptide", "CAS 307297-39-8" ], "type": "Peptide", "category": "Longevity & bioregulators", "goals_use_cases": [ "longevity", "sleep", "anti-aging discussion", "telomere / cellular aging narratives", "telomerase (hTERT) activation talk", "circadian / melatonin talk", "pineal bioregulator interest", "recovery continuity (discussed)", "immune aging discussion (minority)", "geroprotection / mortality-cohort talk (historical Russian literature)", "antioxidant / DNA-damage narratives", "vs TA-65 oral telomerase-class comparison", "vs epithalamin extract identity / dosing debate", "yearly bioregulator course calendars" ], "delivery_methods": [ "subcutaneous", "nasal" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "epitalon", "Epithalon", "Epithalone", "AEDG", "AEDG peptide", "Ala-Glu-Asp-Gly", "sleep", "longevity", "telomere", "pineal", "pcac", "10 day" ], "feel_search": [ "sleep", "longevity", "telomere", "pineal", "pcac", "10 day" ], "summary": "Epitalon is a synthetic four-amino-acid peptide discussed for sleep and longevity. Sleep reports range from deeper rest and vivid dreams to no change or greater wakefulness.", "search_blob": "epitalon epitalon epithalon epithalone aedg peptide aedg ala-glu-asp-gly alagluaspgly epithalamin (related pineal extract; not identical) epithalamine (spelling variant of the extract) khavinson pineal tetrapeptide cas 307297-39-8 epitalon epithalon epithalone aedg aedg peptide ala-glu-asp-gly sleep longevity telomere pineal pcac 10 day longevity sleep anti-aging discussion telomere / cellular aging narratives telomerase (htert) activation talk circadian / melatonin talk pineal bioregulator interest recovery continuity (discussed) immune aging discussion (minority) geroprotection / mortality-cohort talk (historical russian literature) antioxidant / dna-damage narratives vs ta-65 oral telomerase-class comparison vs epithalamin extract identity / dosing debate yearly bioregulator course calendars sleep longevity telomere pineal pcac 10 day epitalon is a synthetic four-amino-acid peptide discussed for sleep and longevity. sleep reports range from deeper rest and vivid dreams to no change or greater wakefulness. one insomnia writer reports better sleep during and soon after a course, then later says the benefit stopped within weeks. a later mixed product is a separate experience. epitalon is a synthetic four-amino-acid peptide discussed for sleep and longevity. sleep reports range from deeper rest and vivid dreams to no change or greater wakefulness. discussion includes short high-milligram courses, longer lower-milligram charts and disputed microgram schedules. epithalamin is a different extract; its amounts are not interchangeable with synthetic epitalon. longevity & bioregulators peptide systemic systemic \u2014 pineal/telomere longevity peptide; not a local injury-site agent. systemic whole-body circulating", "legal_class": null }, { "id": 19, "slug": "semax", "name": "Semax", "aliases": [ "Met-Glu-His-Phe-Pro-Gly-Pro", "N-Acetyl Semax (related)", "MEHFPGP", "H-MEHFPGP-OH", "ACTH(4-7)-PGP", "(Pro8,Gly9,Pro10)ACTH-(4-10)", "ACTH(4-10) analog (heptapeptide shorthand)", "Semax 0.1%", "Semax 1%", "Semax-Hept (1% product talk)", "SEMAX\u00ae (Russian pharmacy brand discussions)", "\u0421\u0435\u043c\u0430\u043a\u0441", "N-Acetyl Semax (related analog \u2014 not identical)", "N-Acetyl Semax Amidate / NASA (related analog \u2014 not identical)", "CAS 80714-61-0 (primary registry discussions)", "MW ~813.93 g/mol (C37H51N9O10S)" ], "type": "Peptide", "category": "Cognitive / nootropic peptides", "goals_use_cases": [ "cognition", "focus", "neuroprotection discussion", "mood", "attention", "working memory (discussed)", "memory / learning support (discussed)", "mental performance under load or fatigue", "stroke / cerebrovascular recovery discussion (Russian clinical history)", "transient ischemic attack discussion (product history)", "optic-nerve / visual-pathway discussion (Russian clinical history)", "mood / stress resilience (mild; secondary to focus for many)", "ADHD-adjacent focus talk (community only; not an approved indication)", "exam / deep-work / high-cognitive-load sprints", "nootropic stacking (classically with Selank)", "peptic-ulcer adjunct discussion (Russian product history \u2014 not Western nootropic use)", "alcohol-delirium / post-toxic cognitive recovery discussion (Russian clinical series)" ], "delivery_methods": [ "nasal", "subcutaneous" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "semax", "Met-Glu-His-Phe-Pro-Gly-Pro", "MEHFPGP", "H-MEHFPGP-OH", "ACTH(4-7)-PGP", "(Pro8,Gly9,Pro10)ACTH-(4-10)", "focus", "brain fog", "exam", "attention", "nasal", "word finding", "anxiety", "insomnia", "hair loss", "hair shedding" ], "feel_search": [ "focus", "brain fog", "exam", "attention", "nasal", "word finding", "anxiety", "insomnia", "hair loss", "hair shedding" ], "summary": "Semax is a synthetic seven-amino-acid peptide derived from an ACTH fragment, discussed for focus and cognitive function.", "search_blob": "semax semax met-glu-his-phe-pro-gly-pro n-acetyl semax (related) mehfpgp h-mehfpgp-oh acth(4-7)-pgp (pro8,gly9,pro10)acth-(4-10) acth(4-10) analog (heptapeptide shorthand) semax 0.1% semax 1% semax-hept (1% product talk) semax\u00ae (russian pharmacy brand discussions) \u0441\u0435\u043c\u0430\u043a\u0441 n-acetyl semax (related analog \u2014 not identical) n-acetyl semax amidate / nasa (related analog \u2014 not identical) cas 80714-61-0 (primary registry discussions) mw ~813.93 g/mol (c37h51n9o10s) semax met-glu-his-phe-pro-gly-pro mehfpgp h-mehfpgp-oh acth(4-7)-pgp (pro8,gly9,pro10)acth-(4-10) focus brain fog exam attention nasal word finding anxiety insomnia hair loss hair shedding cognition focus neuroprotection discussion mood attention working memory (discussed) memory / learning support (discussed) mental performance under load or fatigue stroke / cerebrovascular recovery discussion (russian clinical history) transient ischemic attack discussion (product history) optic-nerve / visual-pathway discussion (russian clinical history) mood / stress resilience (mild; secondary to focus for many) adhd-adjacent focus talk (community only; not an approved indication) exam / deep-work / high-cognitive-load sprints nootropic stacking (classically with selank) peptic-ulcer adjunct discussion (russian product history \u2014 not western nootropic use) alcohol-delirium / post-toxic cognitive recovery discussion (russian clinical series) focus brain fog exam attention nasal word finding anxiety insomnia hair loss hair shedding semax is a synthetic seven-amino-acid peptide derived from an acth fragment, discussed for focus and cognitive function. one user described clearer perception and a calmer sense of well-being, with another drug also in use. semax is a peptide people discuss for focus. some describe less mental drift and easier work without the forced drive they associate with heavy caffeine or adderall-class stimulants. the 'clean focus' comparison is a personal report. nasal burning, anxiety and disrupted sleep also appear in the discussion. cognitive / nootropic peptides peptide systemic brain-first \u2014 intranasal is the main clinical and community route. subcutaneous use is a separate minority practice; oral use is not mainstream. systemic whole-body circulating", "legal_class": null }, { "id": 20, "slug": "selank", "name": "Selank", "aliases": [ "TP-7", "Thr-Lys-Pro-Arg-Pro-Gly-Pro", "TKPRPGP", "Selanc", "\u0421\u0435\u043b\u0430\u043d\u043a", "Selank 0.15% (Russian nasal drops product form)", "tuftsin-derived heptapeptide (research framing)", "threonyl-lysyl-prolyl-arginyl-prolyl-glycyl-proline" ], "type": "Peptide", "category": "Cognitive / nootropic peptides", "goals_use_cases": [ "anxiety discussion", "mood", "cognition", "stress", "anxiety discussion (GAD / generalized anxiety talk)", "mood steadiness", "cognition under stress", "stress / neurasthenia-style fatigue talk", "focus under pressure without stimulant edge", "anxiolytic without benzo-style sedation (discussed)", "social / performance / exam anxiety talk", "immune-modulatory narrative (secondary; tuftsin lineage)", "nootropic stacking (esp. with Semax)", "\u201ccalm focus\u201d stack role vs pure stimulation" ], "delivery_methods": [ "nasal", "subcutaneous" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "selank", "TP-7", "Thr-Lys-Pro-Arg-Pro-Gly-Pro", "TKPRPGP", "Selanc", "\u0421\u0435\u043b\u0430\u043d\u043a", "anxiety", "calm", "stress", "rumination", "brain fog", "flat", "social anxiety", "word finding" ], "feel_search": [ "anxiety", "calm", "stress", "rumination", "brain fog", "flat", "social anxiety", "word finding" ], "summary": "Selank is a synthetic seven-amino-acid analogue of the immune peptide Tuftsin, discussed for anxiety and calm focus.", "search_blob": "selank selank tp-7 thr-lys-pro-arg-pro-gly-pro tkprpgp selanc \u0441\u0435\u043b\u0430\u043d\u043a selank 0.15% (russian nasal drops product form) tuftsin-derived heptapeptide (research framing) threonyl-lysyl-prolyl-arginyl-prolyl-glycyl-proline selank tp-7 thr-lys-pro-arg-pro-gly-pro tkprpgp selanc \u0441\u0435\u043b\u0430\u043d\u043a anxiety calm stress rumination brain fog flat social anxiety word finding anxiety discussion mood cognition stress anxiety discussion (gad / generalized anxiety talk) mood steadiness cognition under stress stress / neurasthenia-style fatigue talk focus under pressure without stimulant edge anxiolytic without benzo-style sedation (discussed) social / performance / exam anxiety talk immune-modulatory narrative (secondary; tuftsin lineage) nootropic stacking (esp. with semax) \u201ccalm focus\u201d stack role vs pure stimulation anxiety calm stress rumination brain fog flat social anxiety word finding selank is a synthetic seven-amino-acid analogue of the immune peptide tuftsin, discussed for anxiety and calm focus. one nasal user described calm, focus and well-being; they stopped repurchasing because of route and product-quality concerns. selank is a peptide discussed for calm and clearer thinking as anxiety eases. accounts do not establish whether the thinking changes are separate from reduced anxiety. often paired with semax. nose irritation is still the #1 complaint. cognitive / nootropic peptides peptide systemic systemic cns framing \u2014 canonical route is intranasal for brain/anxiety endpoints, not local tissue repair. systemic whole-body circulating", "legal_class": null }, { "id": 21, "slug": "thymosin-alpha-1", "name": "Thymosin Alpha-1", "aliases": [ "T\u03b11", "Zadaxin", "Thymalfasin", "Ta1", "TA1", "Thymosin \u03b11", "Thymosin alpha 1", "Thymosin-\u03b11", "T alpha 1", "thymosin a1" ], "type": "Peptide", "category": "Immune peptides", "goals_use_cases": [ "immune", "recovery", "longevity discussion", "immune modulation", "antiviral interest (historical / adjunct)", "oncology adjunct (discussed)", "vaccine response interest", "chronic infection support narratives", "inflammation balance (discussed)", "performance continuity (illness recovery)", "immunosenescence / aging immune talk", "critical illness / sepsis adjunct (trial context)", "long-COVID / post-viral forums (anecdotal)" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "thymosin-alpha-1", "thymosin alpha 1", "thymosinalpha1", "Thymosin Alpha-1", "T\u03b11", "Ta1", "immune", "sick", "cold", "recovery", "CD4", "WBC", "compounding", "10mg vial" ], "feel_search": [ "immune", "sick", "cold", "recovery", "CD4", "WBC", "compounding" ], "summary": "Thymosin alpha-1, or thymalfasin, is a synthetic 28-amino-acid thymic peptide used in immune-related clinical research and treatment.", "search_blob": "thymosin alpha-1 thymosin-alpha-1 t\u03b11 zadaxin thymalfasin ta1 ta1 thymosin \u03b11 thymosin alpha 1 thymosin-\u03b11 t alpha 1 thymosin a1 thymosin-alpha-1 thymosin alpha 1 thymosinalpha1 thymosin alpha-1 t\u03b11 ta1 immune sick cold recovery cd4 wbc compounding 10mg vial immune recovery longevity discussion immune modulation antiviral interest (historical / adjunct) oncology adjunct (discussed) vaccine response interest chronic infection support narratives inflammation balance (discussed) performance continuity (illness recovery) immunosenescence / aging immune talk critical illness / sepsis adjunct (trial context) long-covid / post-viral forums (anecdotal) immune sick cold recovery cd4 wbc compounding thymosin alpha-1, or thymalfasin, is a synthetic 28-amino-acid thymic peptide used in immune-related clinical research and treatment. reports range from clearer sinuses or allergy relief to dizziness, joint discomfort and heartburn; the cause of one adverse reaction remained uncertain. thymosin alpha-1 is an immune-related peptide discussed for recurrent illness, sinus symptoms and allergy concerns. reports include symptom relief, little change and adverse reactions. usually twice a week, not a daily gh-style pin. 1.6 mg is milligrams \u2014 not a bpc mcg chart. ruo 10 mg vials are not one shot. immune peptides peptide systemic systemic \u2014 circulating immune-modulating thymic peptide (t-cell / innate\u2013adaptive host defense), not a local soft-tissue repair agent like tb-500 or bpc-157. systemic whole-body circulating", "legal_class": null }, { "id": 22, "slug": "ll-37", "name": "LL-37", "aliases": [ "Cathelicidin LL-37", "CAP-18 fragment", "Cathelicidin antimicrobial peptide", "hCAP-18 fragment", "CAP-18 C-terminal peptide", "hCAP18-derived peptide", "Ropocamptide (investigational topical designation / Promore Pharma)", "LL37", "LL 37", "Human cathelicidin", "FALL-39 (historical related designation talk)" ], "type": "Peptide", "category": "Immune peptides", "goals_use_cases": [ "immune", "antimicrobial discussion", "skin", "gut health (discussed)", "wound healing (topical trial context)", "anti-biofilm (preclinical)", "chronic infection discussion", "Lyme / mold / CIRS-adjacent forum talk", "sinus / stubborn infection narratives", "inflammation modulation (double-edged)", "post-viral immune-support talk", "host-defense peptide research" ], "delivery_methods": [ "subcutaneous", "topical" ], "discussion_popularity": "High", "reach": "Mixed", "misspellings_search_terms": [ "ll-37", "ll 37", "ll37", "Cathelicidin LL-37", "Cathelicidin antimicrobial peptide", "hCAP-18 fragment", "lyme", "mold", "immune", "itch", "skin", "sibo", "gut", "topical" ], "feel_search": [ "lyme", "mold", "immune", "itch", "skin", "sibo", "gut", "topical" ], "summary": "LL-37 is a human antimicrobial peptide involved in immune signaling, studied experimentally and discussed for difficult infections and wound healing.", "search_blob": "ll-37 ll-37 cathelicidin ll-37 cap-18 fragment cathelicidin antimicrobial peptide hcap-18 fragment cap-18 c-terminal peptide hcap18-derived peptide ropocamptide (investigational topical designation / promore pharma) ll37 ll 37 human cathelicidin fall-39 (historical related designation talk) ll-37 ll 37 ll37 cathelicidin ll-37 cathelicidin antimicrobial peptide hcap-18 fragment lyme mold immune itch skin sibo gut topical immune antimicrobial discussion skin gut health (discussed) wound healing (topical trial context) anti-biofilm (preclinical) chronic infection discussion lyme / mold / cirs-adjacent forum talk sinus / stubborn infection narratives inflammation modulation (double-edged) post-viral immune-support talk host-defense peptide research lyme mold immune itch skin sibo gut topical ll-37 is a human antimicrobial peptide involved in immune signaling, studied experimentally and discussed for difficult infections and wound healing. reports range from little change to local reactions, flu-like symptoms or perceived benefit without cure. co-treatments are common, and a 'herx' feeling does not prove infection is being cleared. ll-37 is a peptide people look up for immune support. reports remain mixed: one user lowered an unspecified amount after early symptoms, and another described benefit without cure. injection accounts describe itching or raised welts. short blocks recur in discussion, but those calendars do not establish safety. immune peptides peptide mixed mixed \u2014 human trials used topical ulcer gel; community infection and immune use is usually subq, and those routes are not interchangeable. mixed local systemic", "legal_class": null }, { "id": 23, "slug": "kpv", "name": "KPV", "aliases": [ "Lys-Pro-Val", "alpha-MSH fragment KPV", "Lysine-Proline-Valine", "\u03b1-MSH(11-13)", "\u03b1-MSH 11-13", "MSH 11-13", "KPV tripeptide", "alpha-MSH C-terminal tripeptide", "Ac-KPV (acetylated forms discussed)" ], "type": "Peptide", "category": "Gut & inflammation peptides", "goals_use_cases": [ "gut health", "inflammation discussion", "skin", "inflammation (discussed)", "GI lining / barrier support (discussed)", "IBD-model research interest (colitis threads)", "skin / dermatitis / barrier irritation", "immune signaling / cytokine calm (discussed)", "histamine / MCAS-adjacent discussion (anecdotal)", "antimicrobial / \u201cbug load\u201d talk (lab angle)", "recovery continuity (as stack partner)", "oral peptide option when injectables are avoided" ], "delivery_methods": [ "oral", "subcutaneous", "topical" ], "discussion_popularity": "High", "reach": "Mixed", "misspellings_search_terms": [ "kpv", "Lys-Pro-Val", "Lysine-Proline-Valine", "alpha-MSH fragment KPV", "\u03b1-MSH(11-13)", "\u03b1-MSH 11-13", "gut", "inflammation", "colitis", "klow", "pcac", "503a", "compounding", "fda approved", "kpv nasal", "calprotectin", "herx", "flare", "nasal" ], "feel_search": [ "gut", "inflammation", "colitis", "klow", "herx", "flare", "nasal" ], "summary": "KPV is a three-amino-acid fragment of alpha-MSH, an experimental peptide discussed for gut discomfort and inflammatory skin symptoms.", "search_blob": "kpv kpv lys-pro-val alpha-msh fragment kpv lysine-proline-valine \u03b1-msh(11-13) \u03b1-msh 11-13 msh 11-13 kpv tripeptide alpha-msh c-terminal tripeptide ac-kpv (acetylated forms discussed) kpv lys-pro-val lysine-proline-valine alpha-msh fragment kpv \u03b1-msh(11-13) \u03b1-msh 11-13 gut inflammation colitis klow pcac 503a compounding fda approved kpv nasal calprotectin herx flare nasal gut health inflammation discussion skin inflammation (discussed) gi lining / barrier support (discussed) ibd-model research interest (colitis threads) skin / dermatitis / barrier irritation immune signaling / cytokine calm (discussed) histamine / mcas-adjacent discussion (anecdotal) antimicrobial / \u201cbug load\u201d talk (lab angle) recovery continuity (as stack partner) oral peptide option when injectables are avoided gut inflammation colitis klow herx flare nasal kpv is a three-amino-acid fragment of alpha-msh, an experimental peptide discussed for gut discomfort and inflammatory skin symptoms. gut reports conflict: some describe less gas or irritation, while others report bloating, diarrhea, dizziness or no benefit. feeling worse does not demonstrate a beneficial 'die-off' reaction. kpv is a peptide discussed for gut symptoms. favorable accounts describe less post-meal irritation and fewer symptom flares during multi-week courses. oral is the gut-first story; subq is the systemic story. don\u2019t treat those mcg as the same. july 2026 compounding-vote headlines are not \u201cfda approved ibd drug.\u201d gut & inflammation peptides peptide mixed mixed \u2014 oral use is discussed for gut symptoms, subq for broader inflammation goals and topical use for skin. these routes are not established as equivalent. mixed local systemic", "legal_class": null }, { "id": 24, "slug": "mots-c", "name": "MOTS-c", "aliases": [ "Mitochondrial ORF of the Twelve S c", "MOTS c", "Mitochondrial open reading frame of the 12S rRNA-c", "MOTSc", "MOTS-C", "mitochondrial-derived peptide MOTS-c", "MRWQEMGYIFYPRKLR", "MT-RNR1-encoded peptide" ], "type": "Peptide", "category": "Mitochondrial & metabolic peptides", "goals_use_cases": [ "metabolic health", "performance", "longevity", "fat loss discussion", "insulin sensitivity (discussed)", "performance / exercise capacity", "exercise mimetic narratives", "longevity / healthspan", "mitochondrial function", "energy / fatigue discussion", "body recomposition (discussed)", "age-related metabolic decline", "glucose handling / metabolic flexibility", "NAFLD / fatty liver discussion (via CB4211 analog trial)", "bone metabolism interest (preclinical)" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "mots-c", "mots c", "motsc", "Mitochondrial ORF of the Twelve S c", "Mitochondrial open reading frame of the 12S rRNA-c", "mitochondrial-derived peptide MOTS-c", "energy", "endurance", "mito", "fat loss", "ATX-304", "ATX", "compounding", "AMPK", "WADA" ], "feel_search": [ "energy", "endurance", "mito", "fat loss", "ATX-304", "AMPK", "WADA" ], "summary": "MOTS-c is a 16-amino-acid mitochondrial peptide studied in metabolism and discussed as an experimental injectable for endurance or recovery.", "search_blob": "mots-c mots-c mitochondrial orf of the twelve s c mots c mitochondrial open reading frame of the 12s rrna-c motsc mots-c mitochondrial-derived peptide mots-c mrwqemgyifyprklr mt-rnr1-encoded peptide mots-c mots c motsc mitochondrial orf of the twelve s c mitochondrial open reading frame of the 12s rrna-c mitochondrial-derived peptide mots-c energy endurance mito fat loss atx-304 atx compounding ampk wada metabolic health performance longevity fat loss discussion insulin sensitivity (discussed) performance / exercise capacity exercise mimetic narratives longevity / healthspan mitochondrial function energy / fatigue discussion body recomposition (discussed) age-related metabolic decline glucose handling / metabolic flexibility nafld / fatty liver discussion (via cb4211 analog trial) bone metabolism interest (preclinical) energy endurance mito fat loss atx-304 ampk wada mots-c is a 16-amino-acid mitochondrial peptide studied in metabolism and discussed as an experimental injectable for endurance or recovery. some report better workouts or endurance; others describe no effect, fatigue, nausea or headaches. injection soreness can be prominent, and benefits may not persist after stopping. mots-c is a mitochondrial peptide discussed for endurance, energy and metabolic health. some users report better workouts; others describe no effect, fatigue or painful injection reactions. community schedules differ between larger weekly injections and smaller daily amounts. neither oral atx-304 comparisons nor the separate cb4211 analog\u2019s 25 mg/day trial establishes a native mots-c dose. mitochondrial & metabolic peptides peptide systemic whole-body metabolic talk, with muscle as the organ people name. systemic whole-body circulating", "legal_class": null }, { "id": 25, "slug": "ss-31", "name": "SS-31", "aliases": [ "Elamipretide", "Bendavia", "MTP-131", "Elamipretide HCl", "MTP131", "Forzinity (FDA brand for Barth syndrome)", "Szeto-Schiller peptide 31", "Szeto-Schiller 31", "D-Arg-Dmt-Lys-Phe-NH2" ], "type": "Peptide", "category": "Mitochondrial & metabolic peptides", "goals_use_cases": [ "longevity", "performance", "mitochondrial discussion", "recovery", "longevity / healthy aging mitochondrial support", "performance and work capacity (discussed)", "mitochondrial disease discussion (Barth, PMM)", "recovery and exercise tolerance", "energy / fatigue reduction (discussed)", "cardiovascular research interest (HFrEF, ischemia)", "muscle function in mito-disease context", "cellular energy / ATP and ROS narratives", "anti-aging cardiolipin / ETC membrane support", "retinal / dry AMD pipeline interest (distinct indication)", "ME/CFS and chronic fatigue experiment talk (anecdotal)", "kidney / ischemia-reperfusion research interest (preclinical)" ], "delivery_methods": [ "subcutaneous", "IV" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "ss-31", "ss 31", "ss31", "Elamipretide", "Elamipretide HCl", "Bendavia", "energy", "fatigue", "mito", "crash", "elamipretide", "5-10 mg", "40 mg", "Forzinity", "high dose" ], "feel_search": [ "energy", "fatigue", "mito", "crash", "elamipretide", "5-10 mg", "40 mg", "Forzinity", "high dose" ], "summary": "SS-31, or elamipretide, is a synthetic four-amino-acid peptide associated with mitochondrial research and energy-related interests.", "search_blob": "ss-31 ss-31 elamipretide bendavia mtp-131 elamipretide hcl mtp131 forzinity (fda brand for barth syndrome) szeto-schiller peptide 31 szeto-schiller 31 d-arg-dmt-lys-phe-nh2 ss-31 ss 31 ss31 elamipretide elamipretide hcl bendavia energy fatigue mito crash elamipretide 5-10 mg 40 mg forzinity high dose longevity performance mitochondrial discussion recovery longevity / healthy aging mitochondrial support performance and work capacity (discussed) mitochondrial disease discussion (barth, pmm) recovery and exercise tolerance energy / fatigue reduction (discussed) cardiovascular research interest (hfref, ischemia) muscle function in mito-disease context cellular energy / atp and ros narratives anti-aging cardiolipin / etc membrane support retinal / dry amd pipeline interest (distinct indication) me/cfs and chronic fatigue experiment talk (anecdotal) kidney / ischemia-reperfusion research interest (preclinical) energy fatigue mito crash elamipretide 5-10 mg 40 mg forzinity high dose ss-31, or elamipretide, is a synthetic four-amino-acid peptide associated with mitochondrial research and energy-related interests. one person with me/cfs described heavier fatigue, nightmares and gi symptoms, later possible energy improvement and another crash. ss-31 is a peptide people look up for longevity. a minority claim next-day recovery or morning energy early \u2014 anecdote only. not a stimulant kick. site redness is the everyday complaint. 2026 also argues 1\u20132 mg vs a 10 mg+ \u201cstop baby-dosing\u201d camp. mitochondrial & metabolic peptides peptide systemic systemic \u2014 mitochondria-targeting tetrapeptide studied by subq and iv routes; forzinity is a narrow barth-syndrome prescription path. systemic whole-body circulating", "legal_class": null }, { "id": 26, "slug": "5-amino-1mq", "name": "5-Amino-1MQ", "aliases": [ "5-amino-1-methylquinolinium", "5A1MQ", "5-amino-1-methylquinolinium iodide", "5-amino-1-methylquinolinium monochloride", "5A-1MQ", "5A-M1Q", "5A-1MQ (monochloride salt)", "5-AMQ", "5-AMQ (PK literature)", "5-Amino-1-MQ", "5 amino 1MQ", "NNMT inhibitor 5-amino-1MQ", "NNMTi 5-amino-1MQ", "NNMTi 5A-1MQ" ], "type": "Non-peptide", "category": "Metabolic research compounds", "goals_use_cases": [ "fat loss", "metabolic health", "NNMT discussion", "body recomposition", "NNMT / NAD+ pathway discussion", "visceral / stubborn fat narratives", "GLP-1 stack adjunct (community)", "insulin sensitivity research (preclinical)", "energy expenditure without appetite cut (animal framing)", "muscle function / aged-muscle talk (preclinical)", "fatty-liver / steatosis interest (preclinical 28-day work)", "longevity / metabolic aging talk (emerging)", "diet-switch synergy (animal framing)", "MitoPrime / multi-agent mito blend talk" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "5-amino-1mq", "5 amino 1mq", "5amino1mq", "5-amino-1-methylquinolinium", "5-amino-1-methylquinolinium iodide", "5-amino-1-methylquinolinium monochloride", "stubborn fat", "recomp", "nnmt", "waist", "flush", "flushing", "50mg", "150mg" ], "feel_search": [ "stubborn fat", "recomp", "nnmt", "waist", "flush", "flushing", "50mg", "150mg" ], "summary": "5-Amino-1MQ is a small-molecule NNMT inhibitor studied for metabolism and discussed for fat loss; it is not a peptide.", "search_blob": "5-amino-1mq 5-amino-1mq 5-amino-1-methylquinolinium 5a1mq 5-amino-1-methylquinolinium iodide 5-amino-1-methylquinolinium monochloride 5a-1mq 5a-m1q 5a-1mq (monochloride salt) 5-amq 5-amq (pk literature) 5-amino-1-mq 5 amino 1mq nnmt inhibitor 5-amino-1mq nnmti 5-amino-1mq nnmti 5a-1mq 5-amino-1mq 5 amino 1mq 5amino1mq 5-amino-1-methylquinolinium 5-amino-1-methylquinolinium iodide 5-amino-1-methylquinolinium monochloride stubborn fat recomp nnmt waist flush flushing 50mg 150mg fat loss metabolic health nnmt discussion body recomposition nnmt / nad+ pathway discussion visceral / stubborn fat narratives glp-1 stack adjunct (community) insulin sensitivity research (preclinical) energy expenditure without appetite cut (animal framing) muscle function / aged-muscle talk (preclinical) fatty-liver / steatosis interest (preclinical 28-day work) longevity / metabolic aging talk (emerging) diet-switch synergy (animal framing) mitoprime / multi-agent mito blend talk stubborn fat recomp nnmt waist flush flushing 50mg 150mg 5-amino-1mq is a small-molecule nnmt inhibitor studied for metabolism and discussed for fat loss; it is not a peptide. a month-long oral log reports no stimulant rush, subtle waist changes after two to three weeks and muted emotions later. diet and training complicate attribution. 5-amino-1mq is a research compound discussed for fat loss, often in oral form. people seek waist changes without strong appetite suppression, frequently alongside glp-1 drugs; these accounts cannot isolate its effects. dose charts are chaotic \u2014 50\u2013150 mg oral vs mcg inject are different worlds. warmth/flush is not a niacin flush. metabolic research compounds non-peptide systemic systemic \u2014 nnmt / nad+ and fat-metabolism discussion; adipose, muscle and liver exposure comes from animal work, not spot-fat targeting. systemic whole-body circulating", "legal_class": null }, { "id": 27, "slug": "slu-pp-332", "name": "SLU-PP-332", "aliases": [ "SLU PP 332", "ERR agonist discussion compound", "SLUPP332", "SLU-PP332", "SLU-PP 332", "ERR pan-agonist (SLU-PP-332)", "ERR agonist exercise-mimetic discussion compound", "Saint Louis University PP-332", "CAS 303760-60-3" ], "type": "Non-peptide", "category": "Metabolic research compounds", "goals_use_cases": [ "fat loss", "endurance discussion", "metabolic health", "exercise-mimetic research", "energy expenditure (discussed)", "mitochondrial / oxidative capacity (discussed)", "body recomposition (discussed)", "performance continuity (discussed)", "fatty-acid oxidation shift (discussed)", "glucose / insulin markers in mice (discussed)", "cardio stamina without more training (discussed)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "slu-pp-332", "slu pp 332", "slupp332", "SLU-PP332", "SLU-PP 332", "ERR pan-agonist (SLU-PP-332)", "endurance", "cardio", "exercise mimetic", "sweat", "915", "enteric", "oral bioavailability", "DMSO" ], "feel_search": [ "endurance", "cardio", "exercise mimetic", "sweat", "915", "enteric", "oral bioavailability", "DMSO" ], "summary": "SLU-PP-332 is an experimental small molecule that activates estrogen-related receptors, studied for metabolic and exercise-like effects.", "search_blob": "slu-pp-332 slu-pp-332 slu pp 332 err agonist discussion compound slupp332 slu-pp332 slu-pp 332 err pan-agonist (slu-pp-332) err agonist exercise-mimetic discussion compound saint louis university pp-332 cas 303760-60-3 slu-pp-332 slu pp 332 slupp332 slu-pp332 slu-pp 332 err pan-agonist (slu-pp-332) endurance cardio exercise mimetic sweat 915 enteric oral bioavailability dmso fat loss endurance discussion metabolic health exercise-mimetic research energy expenditure (discussed) mitochondrial / oxidative capacity (discussed) body recomposition (discussed) performance continuity (discussed) fatty-acid oxidation shift (discussed) glucose / insulin markers in mice (discussed) cardio stamina without more training (discussed) endurance cardio exercise mimetic sweat 915 enteric oral bioavailability dmso slu-pp-332 is an experimental small molecule that activates estrogen-related receptors, studied for metabolic and exercise-like effects. one user described no initial effect, then more energy with evening exhaustion and difficult sleep at a higher amount. slu-pp-332 is an experimental small molecule discussed for endurance and fat loss. oral and injected reports range from no benefit to better workouts, fatigue and disrupted sleep; mouse findings do not establish human effectiveness. reports about 250 mcg capsules and much larger amounts conflict. the separate slu-pp-915 mouse program motivates interest in another oral compound, but does not establish human absorption of either product. metabolic research compounds non-peptide systemic systemic pan-err research aimed at fuel use and muscle oxidative programs; published efficacy is in mice, not local injection-site repair. systemic whole-body circulating", "legal_class": null }, { "id": 28, "slug": "nad-plus", "name": "NAD+", "aliases": [ "Nicotinamide adenine dinucleotide", "NAD plus", "NAD infusions", "NAD", "NAD IV", "NAD drip", "NAD+ therapy", "\u03b2-NAD", "beta-NAD", "Coenzyme 1 (historical label)", "NAD+ injection", "NAD SubQ", "Niagen IV (NR IV comparator brand talk)", "BR+NAD / Brain Restoration Plus NAD (addiction-clinic brand protocol)" ], "type": "Non-peptide", "category": "Longevity & cellular energy", "goals_use_cases": [ "longevity", "energy", "cognition", "recovery", "longevity / anti-aging narrative", "cellular energy / mitochondrial support", "cognition / brain fog / mental clarity", "recovery / burnout reset", "performance continuity / training deload adjacency", "jet lag / travel recovery (discussed)", "addiction-clinic historical / detox / craving support interest", "mood / motivation (anecdotal)", "metabolic / redox talk", "DNA-repair / sirtuin / PARP cofactor framing", "wellness-clinic IV lounge culture", "post-viral / chronic-fatigue clinic menus (marketing, sparse hard trials)", "comparison path vs daily oral NMN or NR" ], "delivery_methods": [ "IV", "subcutaneous", "nasal", "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "nad-plus", "nad plus", "nadplus", "NAD+", "Nicotinamide adenine dinucleotide", "NAD", "brain fog", "energy", "nad drip", "flush", "chest pressure", "crash", "wired", "nausea", "nasal spray", "endotoxin" ], "feel_search": [ "brain fog", "energy", "nad drip", "flush", "chest pressure", "crash", "wired", "nausea", "nasal spray", "endotoxin" ], "summary": "NAD+ is a cellular coenzyme sold as IV drips and injectables for energy or longevity; it differs from oral precursors such as NR and NMN.", "search_blob": "nad+ nad-plus nicotinamide adenine dinucleotide nad plus nad infusions nad nad iv nad drip nad+ therapy \u03b2-nad beta-nad coenzyme 1 (historical label) nad+ injection nad subq niagen iv (nr iv comparator brand talk) br+nad / brain restoration plus nad (addiction-clinic brand protocol) nad-plus nad plus nadplus nad+ nicotinamide adenine dinucleotide nad brain fog energy nad drip flush chest pressure crash wired nausea nasal spray endotoxin longevity energy cognition recovery longevity / anti-aging narrative cellular energy / mitochondrial support cognition / brain fog / mental clarity recovery / burnout reset performance continuity / training deload adjacency jet lag / travel recovery (discussed) addiction-clinic historical / detox / craving support interest mood / motivation (anecdotal) metabolic / redox talk dna-repair / sirtuin / parp cofactor framing wellness-clinic iv lounge culture post-viral / chronic-fatigue clinic menus (marketing, sparse hard trials) comparison path vs daily oral nmn or nr brain fog energy nad drip flush chest pressure crash wired nausea nasal spray endotoxin nad+ is a cellular coenzyme sold as iv drips and injectables for energy or longevity; it differs from oral precursors such as nr and nmn. infusions can feel uncomfortable, with nausea, pressure or anxiety affected by drip speed. later reports range from short-lived clarity to no worthwhile change after several sessions. nad+ is a cellular coenzyme discussed for energy and longevity. some people report feeling recharged or less drained after a drip, while others find no worthwhile change; saline, b vitamins, rest, caffeine and expectations complicate attribution. faster drips are associated with reports of chest pressure and flushing. oral nad+, oral precursors, nasal sprays, subq injections and iv infusions are distinct products or routes; their amounts and effects cannot be assumed equivalent. longevity & cellular energy non-peptide systemic systemic cofactor (redox, sirtuins, parps, mitochondria). systemic whole-body circulating", "legal_class": null }, { "id": 29, "slug": "nmn", "name": "NMN", "aliases": [ "Nicotinamide mononucleotide", "\u03b2-NMN", "beta-NMN", "\u03b2-Nicotinamide mononucleotide", "beta-Nicotinamide mononucleotide", "Nicotinamide mononucleotide (\u03b2 form)", "MIB-626 (pharma-grade / microcrystalline \u03b2-NMN in trials)", "NMN powder / NMN capsules (consumer forms)", "\u03b2-Nicotinamide mononucleotide monohydrate (label chemistry talk)" ], "type": "Non-peptide", "category": "Longevity & cellular energy", "goals_use_cases": [ "longevity", "energy", "metabolic health", "longevity / healthy aging", "cellular NAD+ support", "energy / daytime vitality (subjective)", "metabolic health / insulin sensitivity (discussed)", "physical performance / aerobic capacity (discussed)", "walking endurance / 6-minute walk narratives", "muscle function / older-adult gait and grip (discussed)", "sleep quality / drowsiness (afternoon-dosing trial talk)", "recovery continuity alongside training", "anti-aging media / Sinclair-adjacent hype", "cognitive energy narratives (minority / confounded)", "comparison alternative to NR, niacin, NAD+ IV", "gut NAD / microbiome Preiss\u2013Handler pathway interest (emerging trial talk)" ], "delivery_methods": [ "oral", "sublingual (marketed)" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "nmn", "Nicotinamide mononucleotide", "\u03b2-NMN", "beta-NMN", "\u03b2-Nicotinamide mononucleotide", "beta-Nicotinamide mononucleotide", "energy", "longevity", "brain fog", "nad", "homocysteine", "TMG", "FDA", "sublingual", "insomnia" ], "feel_search": [ "energy", "longevity", "brain fog", "nad", "homocysteine", "sublingual", "insomnia" ], "summary": "NMN is nicotinamide mononucleotide, an oral NAD+ precursor marketed for energy and healthy aging; higher blood NAD+ is not a felt benefit.", "search_blob": "nmn nmn nicotinamide mononucleotide \u03b2-nmn beta-nmn \u03b2-nicotinamide mononucleotide beta-nicotinamide mononucleotide nicotinamide mononucleotide (\u03b2 form) mib-626 (pharma-grade / microcrystalline \u03b2-nmn in trials) nmn powder / nmn capsules (consumer forms) \u03b2-nicotinamide mononucleotide monohydrate (label chemistry talk) nmn nicotinamide mononucleotide \u03b2-nmn beta-nmn \u03b2-nicotinamide mononucleotide beta-nicotinamide mononucleotide energy longevity brain fog nad homocysteine tmg fda sublingual insomnia longevity energy metabolic health longevity / healthy aging cellular nad+ support energy / daytime vitality (subjective) metabolic health / insulin sensitivity (discussed) physical performance / aerobic capacity (discussed) walking endurance / 6-minute walk narratives muscle function / older-adult gait and grip (discussed) sleep quality / drowsiness (afternoon-dosing trial talk) recovery continuity alongside training anti-aging media / sinclair-adjacent hype cognitive energy narratives (minority / confounded) comparison alternative to nr, niacin, nad+ iv gut nad / microbiome preiss\u2013handler pathway interest (emerging trial talk) energy longevity brain fog nad homocysteine sublingual insomnia nmn is nicotinamide mononucleotide, an oral nad+ precursor marketed for energy and healthy aging; higher blood nad+ is not a felt benefit. some describe subtle energy or stamina, while others feel little. gi upset, a wired feeling or earlier waking can occur; positive blood markers do not guarantee feeling better. nmn is an oral nad+ precursor discussed for energy and healthy aging. some users report better recovery or steadier energy; others notice nothing or develop sleep problems. reported amounts include 250 mg in lower-amount discussions, about 500 mg in 2026 product/community accounts and 1 g in copied influencer schedules. these are not recommended starting amounts. longevity & cellular energy non-peptide systemic systemic oral nad+ precursor; blood nad+ rises do not prove equal exposure or benefit in every tissue. systemic whole-body circulating", "legal_class": null }, { "id": 30, "slug": "rapamycin", "name": "Rapamycin", "aliases": [ "Sirolimus", "Rapamune", "Rapamune (brand)", "Rapamune / sirolimus generics", "AY-22989 (historical research designation)", "mTOR inhibitor (class discussion)", "Rapalog parent compound", "Rapa (forum shorthand)", "Sirolimus oral tablet / solution", "Compounded rapamycin (clinic/telehealth form)" ], "type": "Non-peptide", "category": "Longevity & mTOR", "goals_use_cases": [ "longevity", "immune modulation discussion", "anti-aging discussion", "longevity / healthspan", "immune modulation / immunosenescence discussion", "mTOR / cellular aging research", "autophagy / CR-mimetic framing", "healthspan biomarkers (DEXA, lipids, self-report)", "cancer-prevention narratives (research interest; not proven longevity indication)", "metabolic aging interest", "ovarian aging / reproductive aging interest (VIBRANT and related)", "sarcopenia / lean-mass talk (PEARL secondary signals in women)", "periodontal / oral-aging research interest", "companion-animal aging bridge (Dog Aging Project TRIAD)", "ME/CFS / fatigue exploratory talk (community, sparse)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "rapamycin", "Sirolimus", "Rapamune", "Rapamune (brand)", "Rapamune / sirolimus generics", "AY-22989 (historical research designation)", "longevity", "mouth sores", "ulcers", "weekly", "mtor", "grapefruit", "sirolimus", "lipids", "infection", "bloodwork" ], "feel_search": [ "longevity", "mouth sores", "ulcers", "weekly", "mtor", "grapefruit", "sirolimus", "lipids", "infection", "bloodwork" ], "summary": "Rapamycin is sirolimus, a prescription mTOR-inhibiting drug also discussed in longevity experiments.", "search_blob": "rapamycin rapamycin sirolimus rapamune rapamune (brand) rapamune / sirolimus generics ay-22989 (historical research designation) mtor inhibitor (class discussion) rapalog parent compound rapa (forum shorthand) sirolimus oral tablet / solution compounded rapamycin (clinic/telehealth form) rapamycin sirolimus rapamune rapamune (brand) rapamune / sirolimus generics ay-22989 (historical research designation) longevity mouth sores ulcers weekly mtor grapefruit sirolimus lipids infection bloodwork longevity immune modulation discussion anti-aging discussion longevity / healthspan immune modulation / immunosenescence discussion mtor / cellular aging research autophagy / cr-mimetic framing healthspan biomarkers (dexa, lipids, self-report) cancer-prevention narratives (research interest; not proven longevity indication) metabolic aging interest ovarian aging / reproductive aging interest (vibrant and related) sarcopenia / lean-mass talk (pearl secondary signals in women) periodontal / oral-aging research interest companion-animal aging bridge (dog aging project triad) me/cfs / fatigue exploratory talk (community, sparse) longevity mouth sores ulcers weekly mtor grapefruit sirolimus lipids infection bloodwork rapamycin is sirolimus, a prescription mtor-inhibiting drug also discussed in longevity experiments. forum users describe more energy, less aching, or a tired-but-euphoric feeling; several explicitly question how much is placebo. rapamycin is sirolimus, a prescription mtor inhibitor also discussed for healthy aging. mouse studies report lifespan gains, including a commonly cited ~10\u201325% median range; human life extension remains unestablished. longevity & mtor non-peptide systemic systemic \u2014 whole-body mtorc1 modulation via oral absorption; not a local/injury or peptide-style site-injection agent. systemic whole-body circulating", "legal_class": null }, { "id": 31, "slug": "ghrp-2", "name": "GHRP-2", "aliases": [ "Pralmorelin", "KP-102", "Pralmorelin hydrochloride", "KP-102LN", "GPA 748", "GPA-748", "WAY-GPA-748", "GHRP Kaken 100", "Growth hormone-releasing peptide-2", "GHRP2", "GHRP 2", "D-Ala-D-2Nal-Ala-Trp-D-Phe-Lys-NH2" ], "type": "Peptide", "category": "Growth hormone axis", "goals_use_cases": [ "muscle growth", "appetite", "recovery", "fat loss discussion", "appetite / hard-gainer bulk", "body composition", "performance", "sleep (discussed)", "anti-aging discussion", "IGF-1 elevation (discussed)", "GH deficiency diagnostic (Japan, clinical)", "lean recomp with controllable hunger vs GHRP-6" ], "delivery_methods": [ "subcutaneous", "nasal" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "ghrp-2", "ghrp 2", "ghrp2", "Pralmorelin", "Pralmorelin hydrochloride", "KP-102", "hunger", "sleep", "gh pulse", "empty stomach", "compounding", "IGF-1", "prolactin" ], "feel_search": [ "hunger", "sleep", "gh pulse", "empty stomach", "compounding", "IGF-1", "prolactin" ], "summary": "GHRP-2, or pralmorelin, is a growth-hormone-releasing peptide; bodybuilding users discuss it for appetite, recovery and growth-hormone pulses.", "search_blob": "ghrp-2 ghrp-2 pralmorelin kp-102 pralmorelin hydrochloride kp-102ln gpa 748 gpa-748 way-gpa-748 ghrp kaken 100 growth hormone-releasing peptide-2 ghrp2 ghrp 2 d-ala-d-2nal-ala-trp-d-phe-lys-nh2 ghrp-2 ghrp 2 ghrp2 pralmorelin pralmorelin hydrochloride kp-102 hunger sleep gh pulse empty stomach compounding igf-1 prolactin muscle growth appetite recovery fat loss discussion appetite / hard-gainer bulk body composition performance sleep (discussed) anti-aging discussion igf-1 elevation (discussed) gh deficiency diagnostic (japan, clinical) lean recomp with controllable hunger vs ghrp-6 hunger sleep gh pulse empty stomach compounding igf-1 prolactin ghrp-2, or pralmorelin, is a growth-hormone-releasing peptide; bodybuilding users discuss it for appetite, recovery and growth-hormone pulses. hunger, brief warmth or drowsiness are reported soon after use, with sleep changes in some logs. the appetite sensation is distinct from a measured growth-hormone response. ghrp-2 (pralmorelin) is a peptide discussed for growth-hormone release and appetite. older reports describe strongest hunger around 20\u201330 minutes after injection, with flushing, warmth, lightheadedness or drowsiness in some accounts; hunger does not measure gh release. community charts describe a ghrh partner, food-free windows and 1\u20133 injections daily. these are reported practices, with conflicting appetite, sleep and recovery experiences. growth hormone axis peptide systemic systemic \u2014 ghrelin-receptor agonist discussed for pituitary gh pulses, appetite, recovery and body composition; not local joint or muscle targeting. systemic whole-body circulating", "legal_class": null }, { "id": 32, "slug": "ghrp-6", "name": "GHRP-6", "aliases": [ "Growth hormone releasing peptide-6", "Growth hormone-releasing hexapeptide", "GH-releasing peptide-6", "GHRP 6", "GHRP6", "His-D-Trp-Ala-Trp-D-Phe-Lys-NH2", "HwAWfK-NH2", "SK&F 110679", "SKF-110679", "SKF 110679", "Hexapeptide-2", "U 75799E" ], "type": "Peptide", "category": "Growth hormone axis", "goals_use_cases": [ "muscle growth", "appetite", "recovery", "appetite / hard-gainer bulk", "body composition", "performance", "anti-catabolism (discussed)", "sleep adjacency (discussed)", "IGF-1 support (discussed)", "surplus adherence (hunger as lever)", "lean bulk when ravenous appetite is wanted on purpose" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "ghrp-6", "ghrp 6", "ghrp6", "Growth hormone releasing peptide-6", "Growth hormone-releasing hexapeptide", "GH-releasing peptide-6", "hunger", "ravenous", "gh pulse", "empty stomach", "compounding", "IGF-1", "cut" ], "feel_search": [ "hunger", "ravenous", "gh pulse", "empty stomach", "compounding", "IGF-1", "cut" ], "summary": "GHRP-6 is a growth-hormone-releasing peptide known in bodybuilding discussions for strong hunger; appetite can be the desired effect or the drawback.", "search_blob": "ghrp-6 ghrp-6 growth hormone releasing peptide-6 growth hormone-releasing hexapeptide gh-releasing peptide-6 ghrp 6 ghrp6 his-d-trp-ala-trp-d-phe-lys-nh2 hwawfk-nh2 sk&f 110679 skf-110679 skf 110679 hexapeptide-2 u 75799e ghrp-6 ghrp 6 ghrp6 growth hormone releasing peptide-6 growth hormone-releasing hexapeptide gh-releasing peptide-6 hunger ravenous gh pulse empty stomach compounding igf-1 cut muscle growth appetite recovery appetite / hard-gainer bulk body composition performance anti-catabolism (discussed) sleep adjacency (discussed) igf-1 support (discussed) surplus adherence (hunger as lever) lean bulk when ravenous appetite is wanted on purpose hunger ravenous gh pulse empty stomach compounding igf-1 cut ghrp-6 is a growth-hormone-releasing peptide known in bodybuilding discussions for strong hunger; appetite can be the desired effect or the drawback. a strong hunger wave is the most recognizable report, sometimes with warmth, head-rush or site sting. water retention, vivid dreams, nausea or fatigue also appear in longer or stacked logs. ghrp-6 is a peptide people look up for appetite. hunger wave frequently lasts ~30\u201360+ min; many plan a meal in the post-dose window rather than fighting it. bulk logs frame the hunger as a feature; cut logs often find it disruptive. 100 mcg is the saturation lore. growth hormone axis peptide systemic systemic \u2014 ghrelin-receptor peptide discussed for gh pulses, appetite, recovery and body composition; not local joint or muscle targeting. systemic whole-body circulating", "legal_class": null }, { "id": 33, "slug": "hexarelin", "name": "Hexarelin", "aliases": [ "Examorelin", "HEX", "EP-23905", "MF-6003", "His-D-2-methyl-Trp-Ala-Trp-D-Phe-Lys-NH2", "Hexareline (misspelling)" ], "type": "Peptide", "category": "Growth hormone axis", "goals_use_cases": [ "muscle growth", "recovery", "performance", "body composition / recomp", "GH pulse amplitude (acute)", "anti-aging discussion", "cardiac / cardioprotective research interest", "fat loss (discussed, usually secondary to GH/IGF talk)", "sleep quality (mixed reports)", "bone / collagen marker interest (sparse clinical signals)" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "hexarelin", "Examorelin", "HEX", "EP-23905", "MF-6003", "His-D-2-methyl-Trp-Ala-Trp-D-Phe-Lys-NH2", "cortisol", "prolactin", "gh pulse", "strong", "empty stomach", "compounding", "IGF-1", "desensitization" ], "feel_search": [ "cortisol", "prolactin", "gh pulse", "strong", "empty stomach", "compounding", "IGF-1", "desensitization" ], "summary": "Hexarelin (examorelin) is a synthetic growth-hormone-releasing peptide, discussed for recovery and physique changes.", "search_blob": "hexarelin hexarelin examorelin hex ep-23905 mf-6003 his-d-2-methyl-trp-ala-trp-d-phe-lys-nh2 hexareline (misspelling) hexarelin examorelin hex ep-23905 mf-6003 his-d-2-methyl-trp-ala-trp-d-phe-lys-nh2 cortisol prolactin gh pulse strong empty stomach compounding igf-1 desensitization muscle growth recovery performance body composition / recomp gh pulse amplitude (acute) anti-aging discussion cardiac / cardioprotective research interest fat loss (discussed, usually secondary to gh/igf talk) sleep quality (mixed reports) bone / collagen marker interest (sparse clinical signals) cortisol prolactin gh pulse strong empty stomach compounding igf-1 desensitization hexarelin (examorelin) is a synthetic growth-hormone-releasing peptide, discussed for recovery and physique changes. reports include brief warmth, heaviness or fatigue, mild hunger, sleep changes, or little immediate effect. recovery and tingling reports often come from multi-drug stacks. hexarelin is a growth-hormone-releasing peptide discussed for recovery, sleep and physique changes. accounts also describe fatigue, restless nights and hunger; a stronger gh response does not establish better results. about 100 mcg is a commonly quoted amount in community charts, not a validated target. discussion focuses on hormone effects beyond gh and a declining gh response with repeated use. growth hormone axis peptide systemic systemic \u2014 pituitary ghs-r1a (ghrelin receptor) agonist that triggers whole-body gh/igf-1 axis pulses plus modest acth/cortisol and prolactin spillover. systemic whole-body circulating", "legal_class": null }, { "id": 34, "slug": "mod-grf-1-29", "name": "Mod GRF 1-29", "aliases": [ "CJC-1295 without DAC", "Modified GRF 1-29", "CJC no DAC", "CJC-1295 no DAC", "Mod GRF", "Mod GRF (1-29)", "tetra-substituted GRF 1-29", "tetrasubstituted GRF (1-29)", "CJC-1295 (no DAC)", "CJC-1295 No-DAC", "modGRF" ], "type": "Peptide", "category": "Growth hormone axis", "goals_use_cases": [ "muscle growth", "sleep", "recovery", "fat loss", "performance", "body recomposition", "anti-aging (discussed)", "IGF-1 support (discussed)", "lean mass preservation", "skin / recovery adjacency", "nocturnal GH pulse amplification" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "mod-grf-1-29", "mod grf 1 29", "modgrf129", "Mod GRF 1-29", "CJC-1295 without DAC", "CJC-1295 no DAC", "sleep", "cjc no dac", "recovery" ], "feel_search": [ "sleep", "cjc no dac", "recovery" ], "summary": "Mod GRF 1-29 is a short-acting GHRH peptide analog, often sold as CJC-1295 without DAC and paired with ipamorelin for sleep or recovery.", "search_blob": "mod grf 1-29 mod-grf-1-29 cjc-1295 without dac modified grf 1-29 cjc no dac cjc-1295 no dac mod grf mod grf (1-29) tetra-substituted grf 1-29 tetrasubstituted grf (1-29) cjc-1295 (no dac) cjc-1295 no-dac modgrf mod-grf-1-29 mod grf 1 29 modgrf129 mod grf 1-29 cjc-1295 without dac cjc-1295 no dac sleep cjc no dac recovery muscle growth sleep recovery fat loss performance body recomposition anti-aging (discussed) igf-1 support (discussed) lean mass preservation skin / recovery adjacency nocturnal gh pulse amplification sleep cjc no dac recovery mod grf 1-29 is a short-acting ghrh peptide analog, often sold as cjc-1295 without dac and paired with ipamorelin for sleep or recovery. some describe a brief flush, better sleep or easier recovery; others notice nothing after weeks. most reports involve ipamorelin blends, so mod grf's contribution is unclear. mod grf 1-29 is a ghrh peptide discussed for sleep, recovery and body composition. some report easier next-day recovery or less soreness, while others notice no benefit; most accounts involve other peptides and changes in training or diet. the claimed 100 mcg saturation point is disputed community lore. weekly dac charts concern a different, longer-acting form and do not establish no-dac amounts or timing. growth hormone axis peptide systemic systemic \u2014 short-acting ghrh analog; whole-body gh pulses via pituitary ghrh receptors, not local tissue repair. systemic whole-body circulating", "legal_class": null }, { "id": 35, "slug": "peg-mgf", "name": "PEG-MGF", "aliases": [ "Pegylated Mechano Growth Factor", "PEG MGF", "PEGylated Mechano Growth Factor", "PEG-MGF peptide", "Pegylated MGF", "PEGylated MGF", "Peg-MGF", "PEGylated IGF-1Ec (community shorthand)", "PEG-IGF-1Ec (loose forum synonym \u2014 not always the same product)", "Mechano Growth Factor (pegylated form)" ], "type": "Peptide", "category": "Growth factors", "goals_use_cases": [ "muscle growth", "recovery", "performance", "muscle growth / hypertrophy (discussed)", "recovery / training continuity", "post-workout muscle repair talk", "satellite-cell activation / hyperplasia lore", "soft-tissue / muscle-strain recovery (discussed)", "injury-adjacent downtime reduction talk", "localized / site-focused repair discussion", "stack partner with IGF-1 LR3 (\u201ctwo-wave\u201d growth-factor lore)" ], "delivery_methods": [ "intramuscular", "subcutaneous" ], "discussion_popularity": "High", "reach": "Mixed", "misspellings_search_terms": [ "peg-mgf", "peg mgf", "pegmgf", "Pegylated Mechano Growth Factor", "PEG-MGF peptide", "Pegylated MGF", "soreness", "recovery", "pumps" ], "feel_search": [ "soreness", "recovery", "pumps" ], "summary": "PEG-MGF is a label for a modified MGF E-domain peptide discussed for muscle recovery; it is distinct from full-length PEG-IGF-1.", "search_blob": "peg-mgf peg-mgf pegylated mechano growth factor peg mgf pegylated mechano growth factor peg-mgf peptide pegylated mgf pegylated mgf peg-mgf pegylated igf-1ec (community shorthand) peg-igf-1ec (loose forum synonym \u2014 not always the same product) mechano growth factor (pegylated form) peg-mgf peg mgf pegmgf pegylated mechano growth factor peg-mgf peptide pegylated mgf soreness recovery pumps muscle growth recovery performance muscle growth / hypertrophy (discussed) recovery / training continuity post-workout muscle repair talk satellite-cell activation / hyperplasia lore soft-tissue / muscle-strain recovery (discussed) injury-adjacent downtime reduction talk localized / site-focused repair discussion stack partner with igf-1 lr3 (\u201ctwo-wave\u201d growth-factor lore) soreness recovery pumps peg-mgf is a label for a modified mgf e-domain peptide discussed for muscle recovery; it is distinct from full-length peg-igf-1. one account described modest recovery with subq use; another preferred use in the trained muscle. those reports disagree about route. peg-mgf is a modified peptide discussed for muscle recovery. favorable accounts describe less soreness the next day and easier recovery between sessions, often alongside other compounds and training changes. usually training days, 2\u20133\u00d7 a week. site reactions are common. growth factors peptide mixed mixed in discussion: subq use and local im placement both appear; human distribution and a multi-day half-life remain unverified. mixed local systemic", "legal_class": null }, { "id": 36, "slug": "hgh", "name": "Human Growth Hormone (somatropin)", "aliases": [ "HGH", "rhGH", "somatropin", "Genotropin-class discussion", "recombinant human growth hormone", "191aa GH", "191 AA HGH", "somatotrophin / somatotropin (legacy spellings)", "somatrem / met-HGH / 192aa (historical / gray-market contrast)", "Norditropin-class discussion", "Omnitrope-class discussion", "Humatrope-class discussion", "Nutropin-class discussion", "Serostim-class discussion (HIV wasting context)", "pharma GH / \u201cpharma grade\u201d talk" ], "type": "Peptide", "category": "Growth hormone axis", "goals_use_cases": [ "muscle growth", "fat loss", "recovery", "anti-aging discussion", "muscle growth / lean mass (discussed; fluid confound large)", "fat loss / lipolysis / body recomposition", "recovery / training continuity (discussed)", "anti-aging / wellness-clinic discussion", "skin / collagen / \u201cyouthful\u201d look (discussed)", "sleep quality (evening-dose talk; mixed)", "IGF-1 elevation support (discussed)", "performance / aesthetic physique (off-label community)", "clinical adult GH deficiency (GHD) replacement context", "HIV wasting / cachexia (approved somatropin indication context)", "joint / connective-tissue recovery lore (anecdotal; confounded)", "stack amplifier with AAS \u00b1 insulin \u00b1 IGF-1 (community)" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "hgh", "Human Growth Hormone (somatropin)", "human-growth-hormone-(somatropin)", "rhGH", "somatropin", "recombinant human growth hormone", "sleep", "water retention", "carpal", "fat loss", "empty stomach", "compounding", "IGF-1", "split dose", "import alert", "kits" ], "feel_search": [ "sleep", "water retention", "carpal", "fat loss", "hgh", "empty stomach", "compounding", "IGF-1", "split dose", "import alert", "kits" ], "summary": "HGH here means recombinant human growth hormone (somatropin), discussed for hormone replacement, physique changes and recovery.", "search_blob": "human growth hormone (somatropin) hgh hgh rhgh somatropin genotropin-class discussion recombinant human growth hormone 191aa gh 191 aa hgh somatotrophin / somatotropin (legacy spellings) somatrem / met-hgh / 192aa (historical / gray-market contrast) norditropin-class discussion omnitrope-class discussion humatrope-class discussion nutropin-class discussion serostim-class discussion (hiv wasting context) pharma gh / \u201cpharma grade\u201d talk hgh human growth hormone (somatropin) human-growth-hormone-(somatropin) rhgh somatropin recombinant human growth hormone sleep water retention carpal fat loss empty stomach compounding igf-1 split dose import alert kits muscle growth fat loss recovery anti-aging discussion muscle growth / lean mass (discussed; fluid confound large) fat loss / lipolysis / body recomposition recovery / training continuity (discussed) anti-aging / wellness-clinic discussion skin / collagen / \u201cyouthful\u201d look (discussed) sleep quality (evening-dose talk; mixed) igf-1 elevation support (discussed) performance / aesthetic physique (off-label community) clinical adult gh deficiency (ghd) replacement context hiv wasting / cachexia (approved somatropin indication context) joint / connective-tissue recovery lore (anecdotal; confounded) stack amplifier with aas \u00b1 insulin \u00b1 igf-1 (community) sleep water retention carpal fat loss hgh empty stomach compounding igf-1 split dose import alert kits hgh here means recombinant human growth hormone (somatropin), discussed for hormone replacement, physique changes and recovery. some hgh users describe pumps or gradual appearance changes; others mainly notice numb or painful hands. the reviewed fat-loss story also involved clenbuterol, yohimbine and fasted cardio. hgh here means somatropin, manufactured human growth hormone. people discuss physique changes, recovery and sleep, but reports also include no benefit, swelling, numb hands and daytime fatigue. iu labels on gray vials are shaky. ~3 iu \u2248 1 mg is the usual conversion people use. growth hormone axis peptide systemic systemic \u2014 binds gh receptors widely; hepatic igf-1 and whole-body metabolic/body-composition effects. systemic whole-body circulating", "legal_class": null }, { "id": 37, "slug": "cagrilintide", "name": "Cagrilintide", "aliases": [ "Cagri", "amylin analogue discussion", "Cagrilintide acetate (research/compounded discussions)", "Long-acting amylin analogue", "Amylin receptor agonist (class framing)", "DACRA (dual amylin and calcitonin receptor agonist framing)", "AM833 / AM-833 (developmental / research designation)", "NN9838 / NN 9838 (developmental designation)", "NNC0174-0833 / NNC-0174-0833 (Novo compound code)", "CagriSema component (fixed-dose combo with semaglutide)" ], "type": "Peptide", "category": "Metabolic / GLP-1 class", "goals_use_cases": [ "fat loss", "appetite control", "satiety / meal-size reduction", "weight management / obesity", "food noise reduction (discussed)", "metabolic health", "GLP-1 combination interest (CagriSema)", "amylin-pathway / second-axis satiety research", "body recomposition (confounded by lean-mass risk under low intake)", "type 2 diabetes weight + glycemic co-interest (combo programs)", "DIY multi-agonist stack talk (cagri + sema / tirz / reta)", "GLP-1 intolerance bridge talk (mono cagri framed as lower-vomiting option in meta-analyses)" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "cagrilintide", "Cagri", "Cagrilintide acetate (research/compounded discussions)", "Long-acting amylin analogue", "Amylin receptor agonist (class framing)", "DACRA (dual amylin and calcitonin receptor agonist framing)", "fullness", "appetite", "nausea", "amylin", "food noise", "alcohol", "plateau", "compounding", "research use only", "fatigue", "split dose" ], "feel_search": [ "fullness", "appetite", "nausea", "amylin", "food noise", "alcohol", "plateau", "compounding", "research use only", "fatigue", "split dose" ], "summary": "Cagrilintide is a long-acting amylin analogue investigated for appetite and weight management, distinct from GLP-1 drugs.", "search_blob": "cagrilintide cagrilintide cagri amylin analogue discussion cagrilintide acetate (research/compounded discussions) long-acting amylin analogue amylin receptor agonist (class framing) dacra (dual amylin and calcitonin receptor agonist framing) am833 / am-833 (developmental / research designation) nn9838 / nn 9838 (developmental designation) nnc0174-0833 / nnc-0174-0833 (novo compound code) cagrisema component (fixed-dose combo with semaglutide) cagrilintide cagri cagrilintide acetate (research/compounded discussions) long-acting amylin analogue amylin receptor agonist (class framing) dacra (dual amylin and calcitonin receptor agonist framing) fullness appetite nausea amylin food noise alcohol plateau compounding research use only fatigue split dose fat loss appetite control satiety / meal-size reduction weight management / obesity food noise reduction (discussed) metabolic health glp-1 combination interest (cagrisema) amylin-pathway / second-axis satiety research body recomposition (confounded by lean-mass risk under low intake) type 2 diabetes weight + glycemic co-interest (combo programs) diy multi-agonist stack talk (cagri + sema / tirz / reta) glp-1 intolerance bridge talk (mono cagri framed as lower-vomiting option in meta-analyses) fullness appetite nausea amylin food noise alcohol plateau compounding research use only fatigue split dose cagrilintide is a long-acting amylin analogue investigated for appetite and weight management, distinct from glp-1 drugs. first-dose accounts range from little trouble to several days of nausea or dry heaves. many writers also use tirzepatide, making the combination important. cagrilintide is a long-acting amylin analogue discussed for appetite and weight management. some report feeling full after a few bites at low amounts; others report no useful suppression, fatigue or difficulty eating enough. nausea, vomiting and other gastrointestinal symptoms appear in reports. the often-quoted 2.4 mg weekly amount comes from specific study designs; it is not a universal target for community add-ons or blends. metabolic / glp-1 class peptide systemic systemic \u2014 a long-acting amylin analogue studied for satiety and weight management; not a local tissue-repair peptide. systemic whole-body circulating", "legal_class": null }, { "id": 38, "slug": "cagrisema", "name": "CagriSema", "aliases": [ "CagriSema", "cagrilintide/semaglutide combo", "CagriSema (cagrilintide + semaglutide)", "cagrilintide\u2013semaglutide", "Cagri Sema", "cagri-sema", "NN9838 + semaglutide coadministration (developmental discussion)", "amylin + GLP-1 fixed-dose combination (Novo)" ], "type": "Peptide", "category": "Metabolic / GLP-1 class", "goals_use_cases": [ "fat loss", "appetite control", "metabolic health", "fat loss / chronic weight management", "appetite control and meal-size reduction", "food-noise reduction (dual pathway)", "metabolic health / cardiometabolic markers", "type 2 diabetes\u2013adjacent glycemic discussion", "satiety dual-pathway (amylin/calcitonin + GLP-1)", "post-sema plateau add-on curiosity (community)", "body recomposition interest (confounded; lean mass still at risk with large deficits)", "obesity research (investigational fixed-dose combo)" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "cagrisema", "CagriSema (cagrilintide + semaglutide)", "cagrilintide/semaglutide combo", "cagrilintide\u2013semaglutide", "Cagri Sema", "cagri-sema", "food noise", "nausea", "fat loss", "sema", "dual chamber", "blended vial", "brain fog", "shot day", "food baby" ], "feel_search": [ "food noise", "nausea", "fat loss", "sema", "dual chamber", "blended vial", "brain fog", "shot day", "food baby" ], "summary": "CagriSema is an investigational fixed combination of cagrilintide and semaglutide, combining amylin and GLP-1 pathways for weight management.", "search_blob": "cagrisema cagrisema cagrisema cagrilintide/semaglutide combo cagrisema (cagrilintide + semaglutide) cagrilintide\u2013semaglutide cagri sema cagri-sema nn9838 + semaglutide coadministration (developmental discussion) amylin + glp-1 fixed-dose combination (novo) cagrisema cagrisema (cagrilintide + semaglutide) cagrilintide/semaglutide combo cagrilintide\u2013semaglutide cagri sema cagri-sema food noise nausea fat loss sema dual chamber blended vial brain fog shot day food baby fat loss appetite control metabolic health fat loss / chronic weight management appetite control and meal-size reduction food-noise reduction (dual pathway) metabolic health / cardiometabolic markers type 2 diabetes\u2013adjacent glycemic discussion satiety dual-pathway (amylin/calcitonin + glp-1) post-sema plateau add-on curiosity (community) body recomposition interest (confounded; lean mass still at risk with large deficits) obesity research (investigational fixed-dose combo) food noise nausea fat loss sema dual chamber blended vial brain fog shot day food baby cagrisema is an investigational fixed combination of cagrilintide and semaglutide, combining amylin and glp-1 pathways for weight management. a blinded participant reports fullness within hours, then burps, hiccups and reflux. they did not know whether they received the combination, semaglutide or placebo. cagrisema combines cagrilintide and semaglutide for weight-management research. users describe earlier fullness and less grazing, although cravings can persist. some participants remain below the trial's target amount because of gastrointestinal effects. investigator-managed dose holds differ from choices involving unverified community products. metabolic / glp-1 class peptide systemic systemic \u2014 investigational cagrilintide plus semaglutide, studied for appetite, weight and glycemic effects; trial pens differ from gray blends. systemic whole-body circulating", "legal_class": null }, { "id": 39, "slug": "dsip", "name": "DSIP", "aliases": [ "Delta Sleep-Inducing Peptide", "Delta-sleep-inducing peptide", "DSIP nonapeptide", "Emideltide (compounding / INN-style name)", "Deltaran (Russian DSIP-containing preparation; not identical pure research vial)", "Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu", "WAGGDASGE (sequence shorthand)" ], "type": "Peptide", "category": "Sleep / mood", "goals_use_cases": [ "sleep", "stress", "recovery", "deep / slow-wave (delta) sleep", "sleep onset / latency", "sleep efficiency / fewer night arousals", "stress / evening cortisol narratives", "recovery / next-day readiness", "jet lag / shift-work schedule disruption", "sleep architecture interest (wearables / EEG talk)", "vivid / lucid dream interest (side-effect or goal, split)", "chronic insomnia research history", "opiate / alcohol withdrawal historical research (not modern primary bro use)", "pain / stress-axis co-interest (secondary literature)", "narcolepsy / disturbed-sleep historical exploration (sparse)" ], "delivery_methods": [ "subcutaneous", "nasal" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "dsip", "Delta Sleep-Inducing Peptide", "Delta-sleep-inducing peptide", "DSIP nonapeptide", "Emideltide (compounding / INN-style name)", "Deltaran (Russian DSIP-containing preparation; not identical pure research vial)", "sleep", "deep sleep", "insomnia", "oura" ], "feel_search": [ "sleep", "deep sleep", "insomnia", "oura" ], "summary": "DSIP, or delta sleep-inducing peptide, is an experimental nine-amino-acid peptide discussed for sleep; the name does not guarantee sedation.", "search_blob": "dsip dsip delta sleep-inducing peptide delta-sleep-inducing peptide dsip nonapeptide emideltide (compounding / inn-style name) deltaran (russian dsip-containing preparation; not identical pure research vial) trp-ala-gly-gly-asp-ala-ser-gly-glu waggdasge (sequence shorthand) dsip delta sleep-inducing peptide delta-sleep-inducing peptide dsip nonapeptide emideltide (compounding / inn-style name) deltaran (russian dsip-containing preparation; not identical pure research vial) sleep deep sleep insomnia oura sleep stress recovery deep / slow-wave (delta) sleep sleep onset / latency sleep efficiency / fewer night arousals stress / evening cortisol narratives recovery / next-day readiness jet lag / shift-work schedule disruption sleep architecture interest (wearables / eeg talk) vivid / lucid dream interest (side-effect or goal, split) chronic insomnia research history opiate / alcohol withdrawal historical research (not modern primary bro use) pain / stress-axis co-interest (secondary literature) narcolepsy / disturbed-sleep historical exploration (sparse) sleep deep sleep insomnia oura dsip, or delta sleep-inducing peptide, is an experimental nine-amino-acid peptide discussed for sleep; the name does not guarantee sedation. one forum user describes dozing after about half an hour and waking refreshed; another community account reports no sleep benefit at all. dsip is an experimental peptide discussed for deeper sleep and more rested mornings. reports include easier dozing and vivid dreams, but also no benefit, fragmented sleep or next-day grogginess. historical human sleep studies used intravenous administration. modern community charts often describe subcutaneous microgram amounts; the studies do not establish an equivalent amount by that route. sleep / mood peptide systemic systemic \u2014 whole-system sleep/stress neuromodulation and neuroendocrine talk; not local tissue repair. systemic whole-body circulating", "legal_class": null }, { "id": 40, "slug": "kisspeptin-10", "name": "Kisspeptin-10", "aliases": [ "Kisspeptin", "Kp-10", "Metastin fragment discussion", "KP-10", "Kisspeptin 10", "Kisspeptin-10 amide", "Metastin (45-54)", "Metastin fragment (Kp-10)", "KISS-1 (112-121)", "Human metastin 45-54", "YNWNSFGLRF-NH2" ], "type": "Peptide", "category": "Reproductive & endocrine peptides", "goals_use_cases": [ "libido", "fertility discussion", "hormone axis", "LH / FSH stimulation research", "testosterone support (upstream, discussed)", "HPG axis research", "HSDD / low desire research context", "PCT / post-suppression recovery talk", "sexual desire (central pathways, discussed)", "TRT adjunct axis talk", "hypothalamic amenorrhea research context", "secondary hypogonadism discussion" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "kisspeptin-10", "kisspeptin 10", "kisspeptin10", "Kisspeptin", "Kp-10", "Kisspeptin-10 amide", "libido", "lh", "fertility", "hormone", "compounding", "estradiol", "hCG", "PCT" ], "feel_search": [ "libido", "lh", "fertility", "hormone", "compounding", "estradiol", "hCG", "PCT" ], "summary": "Kisspeptin-10 is a reproductive-signaling peptide that activates the GnRH hormone pathway, discussed for fertility, libido and sexual function.", "search_blob": "kisspeptin-10 kisspeptin-10 kisspeptin kp-10 metastin fragment discussion kp-10 kisspeptin 10 kisspeptin-10 amide metastin (45-54) metastin fragment (kp-10) kiss-1 (112-121) human metastin 45-54 ynwnsfglrf-nh2 kisspeptin-10 kisspeptin 10 kisspeptin10 kisspeptin kp-10 kisspeptin-10 amide libido lh fertility hormone compounding estradiol hcg pct libido fertility discussion hormone axis lh / fsh stimulation research testosterone support (upstream, discussed) hpg axis research hsdd / low desire research context pct / post-suppression recovery talk sexual desire (central pathways, discussed) trt adjunct axis talk hypothalamic amenorrhea research context secondary hypogonadism discussion libido lh fertility hormone compounding estradiol hcg pct kisspeptin-10 is a reproductive-signaling peptide that activates the gnrh hormone pathway, discussed for fertility, libido and sexual function. one pssd account described easier orgasm after about a week, with partial improvements over the following weeks. brain fog and motivation did not improve; the author explicitly did not describe a cure. kisspeptin-10 is a reproductive-signaling peptide discussed for libido and sexual function. accounts include easier orgasm or renewed desire, no benefit, and later sleep or mood problems; changes in sexual experience do not establish a hormone or fertility result. kisspeptin-54 iv desire trials used a different peptide form and route. their results do not validate kp-10 vial amounts or schedules. reproductive & endocrine peptides peptide systemic systemic \u2014 upstream hpg signal (kisspeptin \u2192 kiss1r on gnrh neurons \u2192 gnrh \u2192 lh/fsh \u2192 gonadal sex steroids). systemic whole-body circulating", "legal_class": null }, { "id": 41, "slug": "gonadorelin", "name": "Gonadorelin", "aliases": [ "GnRH", "Lutrepulse-class discussion", "Gonadotropin-releasing hormone", "LHRH", "Luteinizing hormone-releasing hormone", "Gonadorelin acetate", "Gonadorelin hydrochloride", "Factrel (clinical brand discussion; US product historically discontinued for commercial reasons)", "Lutrepulse / Lutrelef-class discussion", "pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2", "Pyr-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2" ], "type": "Peptide", "category": "Reproductive & endocrine peptides", "goals_use_cases": [ "hormone axis", "fertility discussion", "libido", "TRT adjunct (discussed)", "HPTA support (discussed)", "pituitary stimulation (diagnostic framing)", "testicular maintenance / anti-atrophy (discussed)", "post-AAS recovery narratives", "PCT discussion", "hypogonadotropic hypogonadism research context", "hCG alternative (access/shortage/compounding-driven)", "functional hypothalamic amenorrhea / ovulation induction (clinical pump context)", "spermatogenesis induction (pulsatile pump / CHH literature)" ], "delivery_methods": [ "subcutaneous", "pulsatile pump (clinical discussion)" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "gonadorelin", "GnRH", "Gonadotropin-releasing hormone", "LHRH", "Luteinizing hormone-releasing hormone", "Gonadorelin acetate", "hormone axis", "fertility discussion", "libido", "trt adjunct (discussed)", "hpta support (discussed)", "pituitary stimulation (diagnostic framing)" ], "feel_search": [ "hormone axis", "fertility discussion", "libido", "trt adjunct (discussed)", "hpta support (discussed)", "pituitary stimulation (diagnostic framing)" ], "summary": "Gonadorelin is synthetic GnRH, a hormone signal to the pituitary; it is discussed for fertility and as a clinic-offered hCG alternative.", "search_blob": "gonadorelin gonadorelin gnrh lutrepulse-class discussion gonadotropin-releasing hormone lhrh luteinizing hormone-releasing hormone gonadorelin acetate gonadorelin hydrochloride factrel (clinical brand discussion; us product historically discontinued for commercial reasons) lutrepulse / lutrelef-class discussion pglu-his-trp-ser-tyr-gly-leu-arg-pro-gly-nh2 pyr-his-trp-ser-tyr-gly-leu-arg-pro-gly-nh2 gonadorelin gnrh gonadotropin-releasing hormone lhrh luteinizing hormone-releasing hormone gonadorelin acetate hormone axis fertility discussion libido trt adjunct (discussed) hpta support (discussed) pituitary stimulation (diagnostic framing) hormone axis fertility discussion libido trt adjunct (discussed) hpta support (discussed) pituitary stimulation (diagnostic framing) testicular maintenance / anti-atrophy (discussed) post-aas recovery narratives pct discussion hypogonadotropic hypogonadism research context hcg alternative (access/shortage/compounding-driven) functional hypothalamic amenorrhea / ovulation induction (clinical pump context) spermatogenesis induction (pulsatile pump / chh literature) hormone axis fertility discussion libido trt adjunct (discussed) hpta support (discussed) pituitary stimulation (diagnostic framing) gonadorelin is synthetic gnrh, a hormone signal to the pituitary; it is discussed for fertility and as a clinic-offered hcg alternative. gonadorelin is discussed for fertility, testicular fullness and libido alongside trt. some describe stronger sexual desire or fuller testicles; others notice no improvement. those observations do not establish sperm production. reproductive & endocrine peptides peptide systemic systemic: synthetic native-sequence decapeptide gnrh hits pituitary gnrh receptors \u2192 lh + fsh \u2192 gonads. systemic whole-body circulating", "legal_class": null }, { "id": 42, "slug": "hcg", "name": "hCG", "aliases": [ "Human chorionic gonadotropin", "Pregnyl-class discussion", "HCG", "Pregnyl", "Novarel", "Profasi (historical urinary brand discussion)", "Ovidrel / choriogonadotropin alfa (recombinant)", "r-hCG", "u-hCG", "chorionic gonadotropin", "beta-hCG (assay/doping talk)", "Gonasi (regional brand talk)", "choriogonadotropin alfa" ], "type": "Peptide", "category": "Reproductive & endocrine peptides", "goals_use_cases": [ "hormone axis", "fertility discussion", "PCT discussion", "TRT fertility preservation", "testicular function / anti-atrophy", "libido", "hypogonadism discussion", "spermatogenesis support", "on-cycle testicular maintenance (AAS talk)", "female ART ovulation / oocyte-maturation trigger", "hypogonadotropic hypogonadism induction", "hCG monotherapy (selected secondary hypogonadism)", "cryptorchidism / puberty induction (historical clinical)", "weight-loss diet lore (FDA-warned; not a supported use)" ], "delivery_methods": [ "subcutaneous", "intramuscular" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "hcg", "Human chorionic gonadotropin", "Pregnyl", "Novarel", "Profasi (historical urinary brand discussion)", "Ovidrel / choriogonadotropin alfa (recombinant)", "hormone axis", "fertility discussion", "pct discussion", "trt fertility preservation", "testicular function / anti-atrophy", "libido" ], "feel_search": [ "hormone axis", "fertility discussion", "pct discussion", "trt fertility preservation", "testicular function / anti-atrophy", "libido" ], "summary": "hCG is a pregnancy hormone that mimics LH at the testes; it is discussed for fertility and maintaining testicular function during TRT.", "search_blob": "hcg hcg human chorionic gonadotropin pregnyl-class discussion hcg pregnyl novarel profasi (historical urinary brand discussion) ovidrel / choriogonadotropin alfa (recombinant) r-hcg u-hcg chorionic gonadotropin beta-hcg (assay/doping talk) gonasi (regional brand talk) choriogonadotropin alfa hcg human chorionic gonadotropin pregnyl novarel profasi (historical urinary brand discussion) ovidrel / choriogonadotropin alfa (recombinant) hormone axis fertility discussion pct discussion trt fertility preservation testicular function / anti-atrophy libido hormone axis fertility discussion pct discussion trt fertility preservation testicular function / anti-atrophy libido hypogonadism discussion spermatogenesis support on-cycle testicular maintenance (aas talk) female art ovulation / oocyte-maturation trigger hypogonadotropic hypogonadism induction hcg monotherapy (selected secondary hypogonadism) cryptorchidism / puberty induction (historical clinical) weight-loss diet lore (fda-warned; not a supported use) hormone axis fertility discussion pct discussion trt fertility preservation testicular function / anti-atrophy libido hcg is a pregnancy hormone that mimics lh at the testes; it is discussed for fertility and maintaining testicular function during trt. hcg is a hormone that mimics luteinizing hormone, discussed for fertility and testicular function during testosterone use. testicular fullness, libido, testosterone and sperm production are separate outcomes. reproductive & endocrine peptides peptide systemic systemic \u2014 lh/cg-receptor agonist on leydig cells (males) and theca/granulosa (females); raises gonadal steroids axis-wide, not a local cosmetic peptide. systemic whole-body circulating", "legal_class": null }, { "id": 43, "slug": "oxytocin", "name": "Oxytocin", "aliases": [ "OT", "love hormone (colloquial)", "OXT", "cuddle hormone (colloquial)", "Syntocinon (pharmaceutical brand contexts)", "Pitocin (pharmaceutical brand / labor-induction contexts)", "oxytocin acetate (research-vial labeling)", "intranasal oxytocin (INOXT / IN-OT research shorthand)" ], "type": "Peptide", "category": "Neuropeptides", "goals_use_cases": [ "social bonding discussion", "mood", "libido", "anxiety discussion", "mood / affiliative affect", "libido and intimacy", "anxiety / social-threat reactivity (discussed)", "pair bonding / relationship closeness (discussed)", "sexual function and orgasm quality (discussed)", "trust / social cognition research", "stress-hormone response in social contexts (research)", "chronic pain adjunct research (intranasal multi-day protocols)", "ASD social outcomes research (mixed / large null trial)", "PTSD / trauma-related social comfort (compounding clinic talk)" ], "delivery_methods": [ "nasal", "subcutaneous" ], "discussion_popularity": "Medium", "reach": "Mixed", "misspellings_search_terms": [ "oxytocin", "OT", "OXT", "love hormone (colloquial)", "cuddle hormone (colloquial)", "Syntocinon (pharmaceutical brand contexts)", "social bonding discussion", "mood / affiliative affect", "libido and intimacy", "anxiety / social-threat reactivity (discussed)", "pair bonding / relationship closeness (discussed)", "sexual function and orgasm quality (discussed)" ], "feel_search": [ "social bonding discussion", "mood / affiliative affect", "libido and intimacy", "anxiety / social-threat reactivity (discussed)", "pair bonding / relationship closeness (discussed)", "sexual function and orgasm quality (discussed)" ], "summary": "Oxytocin is a natural hormone and peptide; nasal products are discussed for closeness and social comfort, separate from its obstetric use.", "search_blob": "oxytocin oxytocin ot love hormone (colloquial) oxt cuddle hormone (colloquial) syntocinon (pharmaceutical brand contexts) pitocin (pharmaceutical brand / labor-induction contexts) oxytocin acetate (research-vial labeling) intranasal oxytocin (inoxt / in-ot research shorthand) oxytocin ot oxt love hormone (colloquial) cuddle hormone (colloquial) syntocinon (pharmaceutical brand contexts) social bonding discussion mood / affiliative affect libido and intimacy anxiety / social-threat reactivity (discussed) pair bonding / relationship closeness (discussed) sexual function and orgasm quality (discussed) social bonding discussion mood libido anxiety discussion mood / affiliative affect libido and intimacy anxiety / social-threat reactivity (discussed) pair bonding / relationship closeness (discussed) sexual function and orgasm quality (discussed) trust / social cognition research stress-hormone response in social contexts (research) chronic pain adjunct research (intranasal multi-day protocols) asd social outcomes research (mixed / large null trial) ptsd / trauma-related social comfort (compounding clinic talk) social bonding discussion mood / affiliative affect libido and intimacy anxiety / social-threat reactivity (discussed) pair bonding / relationship closeness (discussed) sexual function and orgasm quality (discussed) oxytocin is a natural hormone and peptide; nasal products are discussed for closeness and social comfort, separate from its obstetric use. oxytocin is a hormone and peptide; nasal products are discussed for closeness and social comfort. some people describe calm or openness, while others notice only flushing, no useful change or unpleasant symptoms. neuropeptides peptide mixed mixed \u2014 systemic hormone with context-dependent social effects. nasal social-use discussion is distinct from obstetric iv/im use. mixed local systemic", "legal_class": null }, { "id": 44, "slug": "dihexa", "name": "Dihexa", "aliases": [ "PNB-0408", "angiotensin IV analog discussion", "MM-201 (early lab designation in some histories)", "N-hexanoic-Tyr-Ile-(6)-aminohexanoic amide", "N-hexanoic-tyrosine-isoleucine-(6) aminohexanoic amide", "Dihexa peptide", "Dihexa oligopeptide", "Angiotensin IV analog (Dihexa)", "Nle1-Ang IV\u2013derived analog (Dihexa)", "HGF/c-Met potentiator (Dihexa discussions)", "ATH-1017 / fosgonimeton (related clinical candidate \u2014 not identical)" ], "type": "Non-peptide", "category": "Cognitive research compounds", "goals_use_cases": [ "cognition", "neuroplasticity discussion", "memory (research discussion)", "learning / study retention (anecdotal)", "sustained focus (discussed; not a stimulant frame)", "verbal fluency (self-report theme)", "brain fog / mental clarity (community)", "neurodegeneration research interest (Alzheimer-like models)", "synaptogenesis / spinogenesis narrative", "Parkinson\u2019s / motor-recovery research interest (preclinical grant-era talk)", "aged-cognition rescue narrative (rodent models)" ], "delivery_methods": [ "oral", "transdermal (discussed)" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "dihexa", "PNB-0408", "MM-201 (early lab designation in some histories)", "N-hexanoic-Tyr-Ile-(6)-aminohexanoic amide", "N-hexanoic-tyrosine-isoleucine-(6) aminohexanoic amide", "Dihexa peptide", "word finding", "brain fog", "DMSO", "dihexa acetate", "word-finding", "verbal fluency", "headache", "insomnia", "irritability" ], "feel_search": [ "word finding", "word-finding", "brain fog", "verbal fluency", "headache", "insomnia", "irritability" ], "summary": "Dihexa is a stabilized angiotensin-IV-derived research compound investigated for neuronal signaling and discussed as a nootropic.", "search_blob": "dihexa dihexa pnb-0408 angiotensin iv analog discussion mm-201 (early lab designation in some histories) n-hexanoic-tyr-ile-(6)-aminohexanoic amide n-hexanoic-tyrosine-isoleucine-(6) aminohexanoic amide dihexa peptide dihexa oligopeptide angiotensin iv analog (dihexa) nle1-ang iv\u2013derived analog (dihexa) hgf/c-met potentiator (dihexa discussions) ath-1017 / fosgonimeton (related clinical candidate \u2014 not identical) dihexa pnb-0408 mm-201 (early lab designation in some histories) n-hexanoic-tyr-ile-(6)-aminohexanoic amide n-hexanoic-tyrosine-isoleucine-(6) aminohexanoic amide dihexa peptide word finding brain fog dmso dihexa acetate word-finding verbal fluency headache insomnia irritability cognition neuroplasticity discussion memory (research discussion) learning / study retention (anecdotal) sustained focus (discussed; not a stimulant frame) verbal fluency (self-report theme) brain fog / mental clarity (community) neurodegeneration research interest (alzheimer-like models) synaptogenesis / spinogenesis narrative parkinson\u2019s / motor-recovery research interest (preclinical grant-era talk) aged-cognition rescue narrative (rodent models) word finding word-finding brain fog verbal fluency headache insomnia irritability dihexa is a stabilized angiotensin-iv-derived research compound investigated for neuronal signaling and discussed as a nootropic. one two-week user feels no obvious change but reports better chess results. occasional modafinil and eutropoflavin, practice effects and unstated route limit interpretation. dihexa is a peptide people look up for cognition. working memory under load, study retention, easier encoding over multi-week windows \u2014 gradual, not day-one stimulant lift. reports include learning practice alongside use, headache and no effect. nonresponse does not prove a counterfeit product. not a july 2026 pcac peptide. cognitive research compounds non-peptide systemic systemic brain-focused discussion\u2014oral or transdermal community products, not local muscle-site dosing; human exposure is unverified. systemic whole-body circulating", "legal_class": null }, { "id": 45, "slug": "n-acetyl-semax-amidate", "name": "N-Acetyl Semax Amidate", "aliases": [ "NASA", "NA-Semax Amidate", "Acetyl Semax Amidate", "NA Semax Amidate", "NA-Semax-Amidate", "N-Acetyl-Semax-Amidate", "N-Ac-Semax-NH2", "Ac-MEHFPGP-NH2 (sequence shorthand)", "Ac-Met-Glu-His-Phe-Pro-Gly-Pro-NH2", "N-Acetyl Semax (related single-cap analog \u2014 not identical)", "Semax Amidate (informal; incomplete name)" ], "type": "Peptide", "category": "Cognitive / nootropic peptides", "goals_use_cases": [ "cognition", "focus", "mood", "attention", "working memory (discussed)", "mental performance under stress", "mental stamina / deep-work endurance", "memory / learning support (discussed)", "neuroprotection discussion (inherited from parent Semax)", "nootropic stacking (especially with Selank-class)", "ADHD-adjacent focus talk (community only; not an approved indication)", "exam / sprint cognitive support" ], "delivery_methods": [ "nasal" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "n-acetyl-semax-amidate", "n acetyl semax amidate", "nacetylsemaxamidate", "N-Acetyl Semax Amidate", "NASA", "NA-Semax Amidate", "cognition", "focus", "attention", "working memory (discussed)", "mood", "mental performance under stress" ], "feel_search": [ "cognition", "focus", "attention", "working memory (discussed)", "mood", "mental performance under stress" ], "summary": "N-acetyl Semax amidate is a modified Semax peptide sold for focus and mental stamina; its claimed longer action is not well established.", "search_blob": "n-acetyl semax amidate n-acetyl-semax-amidate nasa na-semax amidate acetyl semax amidate na semax amidate na-semax-amidate n-acetyl-semax-amidate n-ac-semax-nh2 ac-mehfpgp-nh2 (sequence shorthand) ac-met-glu-his-phe-pro-gly-pro-nh2 n-acetyl semax (related single-cap analog \u2014 not identical) semax amidate (informal; incomplete name) n-acetyl-semax-amidate n acetyl semax amidate nacetylsemaxamidate n-acetyl semax amidate nasa na-semax amidate cognition focus attention working memory (discussed) mood mental performance under stress cognition focus mood attention working memory (discussed) mental performance under stress mental stamina / deep-work endurance memory / learning support (discussed) neuroprotection discussion (inherited from parent semax) nootropic stacking (especially with selank-class) adhd-adjacent focus talk (community only; not an approved indication) exam / sprint cognitive support cognition focus attention working memory (discussed) mood mental performance under stress n-acetyl semax amidate is a modified semax peptide sold for focus and mental stamina; its claimed longer action is not well established. reports range from alertness and easier attention to no effect, brain fog, anxiety or a later crash. other brain treatments, caffeine and p21 commonly cloud attribution. n-acetyl semax amidate is a modified semax peptide discussed for focus, mental stamina and mood. reports include clearer thinking, but also no benefit, brain fog, anxiety or sleep disruption; stronger or longer action is not established. cognitive / nootropic peptides peptide systemic brain-first research analog \u2014 intranasal discussion dominates; subq is a minority systemic route, and oral use is not established. systemic whole-body circulating", "legal_class": null }, { "id": 46, "slug": "n-acetyl-selank-amidate", "name": "N-Acetyl Selank Amidate", "aliases": [ "N-Acetyl Selank", "NA-Selank Amidate", "NA-Selank", "NA Selank Amidate", "Acetyl-Selank Amidate", "N-Acetyl-Selank-Amidate", "NA Selank", "Ac-Thr-Lys-Pro-Arg-Pro-Gly-Pro-NH2", "Ac-TKPRPGP-NH2 (sequence shorthand)", "N-Ac-Selank-NH2" ], "type": "Peptide", "category": "Cognitive / nootropic peptides", "goals_use_cases": [ "anxiety discussion", "mood", "cognition", "anxiety discussion (GAD / social / baseline edge)", "mood steadiness", "cognition under stress (secondary to anxiolysis)", "stress / high-demand work or exam windows", "calm focus without heavy sedation (discussed)", "anxiolytic without benzo-style fog/dependence narrative (borrowed from parent Selank)", "social / performance anxiety talk", "nootropic stacking (classic pair with NA-Semax Amidate)", "longer-lasting Selank analog search (stability marketing)", "\u201ccalm half\u201d of Semax/Selank dual stacks" ], "delivery_methods": [ "nasal" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "n-acetyl-selank-amidate", "n acetyl selank amidate", "nacetylselankamidate", "N-Acetyl Selank Amidate", "N-Acetyl Selank", "NA-Selank Amidate", "anxiety discussion (gad / social / baseline edge)", "mood steadiness", "cognition under stress (secondary to anxiolysis)", "stress / high-demand work or exam windows", "calm focus without heavy sedation (discussed)", "anxiolytic without benzo-style fog/dependence narrative (borrowed from parent selank)" ], "feel_search": [ "anxiety discussion (gad / social / baseline edge)", "mood steadiness", "cognition under stress (secondary to anxiolysis)", "stress / high-demand work or exam windows", "calm focus without heavy sedation (discussed)", "anxiolytic without benzo-style fog/dependence narrative (borrowed from parent selank)" ], "summary": "N-acetyl Selank amidate is a chemically modified Selank peptide sold for anxiety and calm focus; claims of longer action are uncertain.", "search_blob": "n-acetyl selank amidate n-acetyl-selank-amidate n-acetyl selank na-selank amidate na-selank na selank amidate acetyl-selank amidate n-acetyl-selank-amidate na selank ac-thr-lys-pro-arg-pro-gly-pro-nh2 ac-tkprpgp-nh2 (sequence shorthand) n-ac-selank-nh2 n-acetyl-selank-amidate n acetyl selank amidate nacetylselankamidate n-acetyl selank amidate n-acetyl selank na-selank amidate anxiety discussion (gad / social / baseline edge) mood steadiness cognition under stress (secondary to anxiolysis) stress / high-demand work or exam windows calm focus without heavy sedation (discussed) anxiolytic without benzo-style fog/dependence narrative (borrowed from parent selank) anxiety discussion mood cognition anxiety discussion (gad / social / baseline edge) mood steadiness cognition under stress (secondary to anxiolysis) stress / high-demand work or exam windows calm focus without heavy sedation (discussed) anxiolytic without benzo-style fog/dependence narrative (borrowed from parent selank) social / performance anxiety talk nootropic stacking (classic pair with na-semax amidate) longer-lasting selank analog search (stability marketing) \u201ccalm half\u201d of semax/selank dual stacks anxiety discussion (gad / social / baseline edge) mood steadiness cognition under stress (secondary to anxiolysis) stress / high-demand work or exam windows calm focus without heavy sedation (discussed) anxiolytic without benzo-style fog/dependence narrative (borrowed from parent selank) n-acetyl selank amidate is a chemically modified selank peptide sold for anxiety and calm focus; claims of longer action are uncertain. some describe calm or reduced rumination, while others notice little, head pressure or an odd detached feeling. product names often fail to confirm whether amidation is present. n-acetyl selank amidate is a modified selank peptide discussed for anxiety and calm focus. accounts include pronounced calm, gradual relief from thought loops, no benefit and unpleasant detached feelings; product names do not always confirm the exact form. cognitive / nootropic peptides peptide systemic systemic cns framing \u2014 research-chem and community use is almost entirely intranasal for anxiolytic/nootropic goals, not local tissue repair. systemic whole-body circulating", "legal_class": null }, { "id": 47, "slug": "pinealon", "name": "Pinealon", "aliases": [ "EDR peptide", "pineal bioregulator", "EDR", "Glu-Asp-Arg", "Glu Asp Arg", "Pinealon peptide", "Khavinson EDR tripeptide", "Cortexin-associated EDR (research context)", "cytomed-class oral Pinealon (marketed bioregulator forms)" ], "type": "Peptide", "category": "Longevity & bioregulators", "goals_use_cases": [ "cognition", "sleep", "longevity", "cognition / memory & attention", "sleep quality & REM narratives", "circadian / pineal interest", "longevity / geroprotection talk", "neuroprotection (discussed)", "brain fog / mental performance (community)", "aging-brain support narratives", "post-stress or TBI-sequelae cognitive adjunct talk (historical clinical narratives)", "oxidative-stress / neuronal ROS reduction interest", "vs Epitalon dual-pineal stack searches" ], "delivery_methods": [ "subcutaneous", "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "pinealon", "EDR peptide", "EDR", "Glu-Asp-Arg", "Glu Asp Arg", "pineal bioregulator", "brain fog", "word finding", "verbal fluency", "emideltide (DSIP \u2014 not Pinealon)", "fog", "word-finding", "word recall", "rem sleep", "deep sleep", "slow wave", "garmin", "clarity", "morning crash", "groggy", "nothing" ], "feel_search": [ "brain fog", "fog", "word finding", "word-finding", "verbal fluency", "word recall", "rem sleep", "deep sleep", "slow wave", "garmin", "clarity", "morning crash", "groggy", "nothing" ], "summary": "Pinealon is the synthetic three-amino-acid peptide EDR, discussed as a brain-focused bioregulator for sleep and cognitive aging.", "search_blob": "pinealon pinealon edr peptide pineal bioregulator edr glu-asp-arg glu asp arg pinealon peptide khavinson edr tripeptide cortexin-associated edr (research context) cytomed-class oral pinealon (marketed bioregulator forms) pinealon edr peptide edr glu-asp-arg glu asp arg pineal bioregulator brain fog word finding verbal fluency emideltide (dsip \u2014 not pinealon) fog word-finding word recall rem sleep deep sleep slow wave garmin clarity morning crash groggy nothing cognition sleep longevity cognition / memory & attention sleep quality & rem narratives circadian / pineal interest longevity / geroprotection talk neuroprotection (discussed) brain fog / mental performance (community) aging-brain support narratives post-stress or tbi-sequelae cognitive adjunct talk (historical clinical narratives) oxidative-stress / neuronal ros reduction interest vs epitalon dual-pineal stack searches brain fog fog word finding word-finding verbal fluency word recall rem sleep deep sleep slow wave garmin clarity morning crash groggy nothing pinealon is the synthetic three-amino-acid peptide edr, discussed as a brain-focused bioregulator for sleep and cognitive aging. one intranasal user described daytime stimulation followed by sleepiness, while bedtime use brought vivid dreams; exercise and timing varied. pinealon is a synthetic peptide discussed for sleep and cognition. favorable accounts describe more restorative nights, less heavy-headedness and easier concentration. improved sleep scores coexist with nonresponse and restless sleep. morning and bedtime preferences differ, and epitalon combinations make attribution difficult. longevity & bioregulators peptide systemic systemic \u2014 cns/pineal-class bioregulator tripeptide discussed for brain, sleep, and gene-expression effects; not a local injury-site agent. systemic whole-body circulating", "legal_class": null }, { "id": 48, "slug": "thymosin-beta-4", "name": "Thymosin Beta-4", "aliases": [ "T\u03b24", "Timbetasin", "full-sequence TB4", "TB4", "TB-4", "Thymosin \u03b24", "Timbetasin (INN)", "full-length thymosin beta-4", "RGN-259 (0.1% ophthalmic research formulation)", "TMSB4X gene product (endogenous context)", "synthetic T\u03b24 (clinical IV / wound-gel programs)" ], "type": "Peptide", "category": "Healing & repair", "goals_use_cases": [ "recovery", "injury repair", "inflammation discussion", "soft-tissue healing", "wound healing (clinical + community)", "inflammation (discussed)", "joints & tendons", "mobility / flexibility", "muscle soft-tissue", "post-strain / overuse bounce-back", "dermal / ulcer repair (trial context)", "ocular surface research (dry eye, neurotrophic keratopathy)", "cardiac ischemia / cardioprotection research (preclinical + early clinical)", "skin/hair (minority discussion)", "performance continuity", "systemic repair narrative (full molecule vs fragment debate)" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Medium", "reach": "Mixed", "misspellings_search_terms": [ "thymosin-beta-4", "thymosin beta 4", "thymosinbeta4", "Thymosin Beta-4", "T\u03b24", "TB4", "recovery", "injury repair", "soft-tissue healing", "wound healing (clinical + community)", "inflammation (discussed)", "joints & tendons" ], "feel_search": [ "recovery", "injury repair", "soft-tissue healing", "wound healing (clinical + community)", "inflammation (discussed)", "joints & tendons" ], "summary": "Thymosin beta-4 is a natural 43-amino-acid peptide studied for tissue repair; the full-length peptide differs from shorter TB-500 fragments.", "search_blob": "thymosin beta-4 thymosin-beta-4 t\u03b24 timbetasin full-sequence tb4 tb4 tb-4 thymosin \u03b24 timbetasin (inn) full-length thymosin beta-4 rgn-259 (0.1% ophthalmic research formulation) tmsb4x gene product (endogenous context) synthetic t\u03b24 (clinical iv / wound-gel programs) thymosin-beta-4 thymosin beta 4 thymosinbeta4 thymosin beta-4 t\u03b24 tb4 recovery injury repair soft-tissue healing wound healing (clinical + community) inflammation (discussed) joints & tendons recovery injury repair inflammation discussion soft-tissue healing wound healing (clinical + community) inflammation (discussed) joints & tendons mobility / flexibility muscle soft-tissue post-strain / overuse bounce-back dermal / ulcer repair (trial context) ocular surface research (dry eye, neurotrophic keratopathy) cardiac ischemia / cardioprotection research (preclinical + early clinical) skin/hair (minority discussion) performance continuity systemic repair narrative (full molecule vs fragment debate) recovery injury repair soft-tissue healing wound healing (clinical + community) inflammation (discussed) joints & tendons thymosin beta-4 is a natural 43-amino-acid peptide studied for tissue repair; the full-length peptide differs from shorter tb-500 fragments. one combined bpc/tb4 user reported an improved elbow but still needed a shoulder cortisone injection; the product's identity was disputed. thymosin beta-4 is a naturally occurring peptide discussed for injury recovery. reports include easier movement, no improvement and fatigue; products called tb-500 may contain a different fragment. healing & repair peptide mixed mixed \u2014 research-chem injectables are treated as systemic soft-tissue repair; clinical programs also use topical wound gels and ophthalmic drops. mixed local systemic", "legal_class": null }, { "id": 49, "slug": "follistatin-344", "name": "Follistatin 344", "aliases": [ "FST-344", "FS-344", "Follistatin", "gray FS-344", "FS344", "FST344", "Follistatin-344", "FST-344 (precursor \u2192 FS-315)", "FS344 / FS315 isoform family", "AAV1-FS344 (gene-therapy context)", "recombinant follistatin (research peptide)" ], "type": "Peptide", "category": "Growth factors", "goals_use_cases": [ "muscle growth", "myostatin discussion", "performance", "muscle growth / hypertrophy (discussed)", "myostatin inhibition pathway interest", "performance / strength (discussed)", "lean mass / body recomposition (discussed)", "recovery (secondary discussion)", "site / regional muscle emphasis (IM talk)", "gene therapy research interest (BMD / sIBM / longevity clinics)", "sarcopenia / age-related muscle loss framing (longevity discourse)", "vs other myostatin-class agents (ACE-031, YK-11, antibodies)" ], "delivery_methods": [ "gene therapy discussion", "research peptide injection discussion" ], "discussion_popularity": "Medium", "reach": "Mixed", "misspellings_search_terms": [ "follistatin-344", "follistatin 344", "follistatin344", "FST-344", "FS-344", "FS344", "fst 344 pip", "follistatin iron den", "flgr vs fst-344", "muscle growth / hypertrophy (discussed)", "myostatin inhibition pathway interest", "performance / strength (discussed)", "lean mass / body recomposition (discussed)", "recovery (secondary discussion)", "site / regional muscle emphasis (im talk)", "pip only", "iron den follistatin", "flgr mixup", "100 dollars a vial" ], "feel_search": [ "muscle growth / hypertrophy (discussed)", "myostatin inhibition pathway interest", "performance / strength (discussed)", "lean mass / body recomposition (discussed)", "recovery (secondary discussion)", "site / regional muscle emphasis (im talk)", "pip only", "iron den follistatin", "flgr mixup", "100 dollars a vial" ], "summary": "Follistatin-344 is a precursor protein discussed for muscle growth through myostatin binding; gene therapy and injectable-protein products are different interventions.", "search_blob": "follistatin 344 follistatin-344 fst-344 fs-344 follistatin gray fs-344 fs344 fst344 follistatin-344 fst-344 (precursor \u2192 fs-315) fs344 / fs315 isoform family aav1-fs344 (gene-therapy context) recombinant follistatin (research peptide) follistatin-344 follistatin 344 follistatin344 fst-344 fs-344 fs344 fst 344 pip follistatin iron den flgr vs fst-344 muscle growth / hypertrophy (discussed) myostatin inhibition pathway interest performance / strength (discussed) lean mass / body recomposition (discussed) recovery (secondary discussion) site / regional muscle emphasis (im talk) pip only iron den follistatin flgr mixup 100 dollars a vial muscle growth myostatin discussion performance muscle growth / hypertrophy (discussed) myostatin inhibition pathway interest performance / strength (discussed) lean mass / body recomposition (discussed) recovery (secondary discussion) site / regional muscle emphasis (im talk) gene therapy research interest (bmd / sibm / longevity clinics) sarcopenia / age-related muscle loss framing (longevity discourse) vs other myostatin-class agents (ace-031, yk-11, antibodies) muscle growth / hypertrophy (discussed) myostatin inhibition pathway interest performance / strength (discussed) lean mass / body recomposition (discussed) recovery (secondary discussion) site / regional muscle emphasis (im talk) pip only iron den follistatin flgr mixup 100 dollars a vial follistatin-344 is a precursor protein discussed for muscle growth through myostatin binding; gene therapy and injectable-protein products are different interventions. a forum user claims retained strength gains, while others question product identity and evidence. these brief accounts do not establish muscle growth from a verified protein product. follistatin 344 is a precursor protein discussed for muscle growth. accounts include fuller muscles, stronger pumps and soreness, but also no change, fatigue or painful reactions; training, other drugs and uncertain vial contents complicate attribution. flgr milligram amounts and the quoted 20-day, 100 mcg quarterly chart concern different product claims from ordinary 1 mg research vials. aav gene delivery is another distinct intervention. growth factors peptide mixed mixed and contested. mixed local systemic", "legal_class": null }, { "id": 50, "slug": "mgf", "name": "MGF (Mechano Growth Factor)", "aliases": [ "IGF-1 Ec", "non-PEGylated MGF", "Mechano Growth Factor", "Mechano-Growth Factor", "IGF-1Ec", "IGF-IEc", "IGF-1 Eb (rodent nomenclature confusion)", "MGF-E", "MGF E-peptide", "MGF-Ct24E", "MGF-24aa-E", "native MGF", "unmodified MGF", "IGF-1Ec E-domain peptide" ], "type": "Peptide", "category": "Growth factors", "goals_use_cases": [ "muscle growth", "recovery", "muscle growth / hypertrophy (discussed)", "recovery / post-workout repair talk", "satellite-cell activation / progenitor-pool lore", "localized / site-specific muscle repair discussion", "hypertrophy adjunct on progressive-overload blocks", "injury-adjacent soft-tissue / muscle-strain downtime talk", "performance / training continuity", "age-related anabolic-resistance / sarcopenia discussion (research framing)", "stack partner with IGF-1 LR3 (\u201cproliferation then differentiation\u201d lore)" ], "delivery_methods": [ "intramuscular" ], "discussion_popularity": "Medium", "reach": "Local", "misspellings_search_terms": [ "mgf", "MGF (Mechano Growth Factor)", "mgf-(mechano-growth-factor)", "Mechano Growth Factor", "Mechano-Growth Factor", "IGF-1 Ec", "muscle growth / hypertrophy (discussed)", "recovery / post-workout repair talk", "satellite-cell activation / progenitor-pool lore", "localized / site-specific muscle repair discussion", "hypertrophy adjunct on progressive-overload blocks", "injury-adjacent soft-tissue / muscle-strain downtime talk" ], "feel_search": [ "muscle growth / hypertrophy (discussed)", "recovery / post-workout repair talk", "satellite-cell activation / progenitor-pool lore", "localized / site-specific muscle repair discussion", "hypertrophy adjunct on progressive-overload blocks", "injury-adjacent soft-tissue / muscle-strain downtime talk" ], "summary": "MGF covers IGF-1Ec research and synthetic E-domain peptides sold for muscle recovery; a vial is not the same thing as the body's IGF-1Ec.", "search_blob": "mgf (mechano growth factor) mgf igf-1 ec non-pegylated mgf mechano growth factor mechano-growth factor igf-1ec igf-iec igf-1 eb (rodent nomenclature confusion) mgf-e mgf e-peptide mgf-ct24e mgf-24aa-e native mgf unmodified mgf igf-1ec e-domain peptide mgf mgf (mechano growth factor) mgf-(mechano-growth-factor) mechano growth factor mechano-growth factor igf-1 ec muscle growth / hypertrophy (discussed) recovery / post-workout repair talk satellite-cell activation / progenitor-pool lore localized / site-specific muscle repair discussion hypertrophy adjunct on progressive-overload blocks injury-adjacent soft-tissue / muscle-strain downtime talk muscle growth recovery muscle growth / hypertrophy (discussed) recovery / post-workout repair talk satellite-cell activation / progenitor-pool lore localized / site-specific muscle repair discussion hypertrophy adjunct on progressive-overload blocks injury-adjacent soft-tissue / muscle-strain downtime talk performance / training continuity age-related anabolic-resistance / sarcopenia discussion (research framing) stack partner with igf-1 lr3 (\u201cproliferation then differentiation\u201d lore) muscle growth / hypertrophy (discussed) recovery / post-workout repair talk satellite-cell activation / progenitor-pool lore localized / site-specific muscle repair discussion hypertrophy adjunct on progressive-overload blocks injury-adjacent soft-tissue / muscle-strain downtime talk mgf covers igf-1ec research and synthetic e-domain peptides sold for muscle recovery; a vial is not the same thing as the body's igf-1ec. people report anything from less local soreness to no benefit. injection-site sting or fullness can be noticeable; longer-term muscle gains are hard to separate from training. mgf (mechano growth factor) products are discussed for muscle recovery and growth. accounts describe less soreness or local fullness alongside little or no added progress; training and other agents complicate attribution. growth factors peptide local local use is the aim: accounts describe injections in or near recently trained muscle, without proving local-only action. local site pin topical", "legal_class": null }, { "id": 51, "slug": "ara-290", "name": "ARA-290", "aliases": [ "Cibinetide", "pyroglutamate helix B surface peptide", "pHBSP", "PHBSP", "Pyroglutamate HBSP", "ARA 290", "ARA290", "Helix B surface peptide", "pGlu-Glu-Gln-Leu-Glu-Arg-Ala-Leu-Asn-Ser-Ser" ], "type": "Peptide", "category": "Healing & repair", "goals_use_cases": [ "neuropathy discussion", "inflammation discussion", "recovery", "small fiber neuropathy (SFN)", "sarcoidosis-associated neuropathic pain", "diabetic peripheral neuropathy discussion", "neuropathic pain (burning, tingling, allodynia)", "corneal / small-nerve fiber repair narrative", "inflammation / tissue-protection discussion", "metabolic adjacency (HbA1c / lipids in T2D trial)", "recovery and nerve-support stacks (community)", "disease-modification hope vs symptom-only relief debate" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "ara-290", "ara 290", "ara290", "Cibinetide", "pHBSP", "pyroglutamate helix B surface peptide", "small fiber neuropathy (sfn)", "sarcoidosis-associated neuropathic pain", "diabetic peripheral neuropathy discussion", "neuropathic pain (burning, tingling, allodynia)", "corneal / small-nerve fiber repair narrative", "inflammation / tissue-protection discussion" ], "feel_search": [ "small fiber neuropathy (sfn)", "sarcoidosis-associated neuropathic pain", "diabetic peripheral neuropathy discussion", "neuropathic pain (burning, tingling, allodynia)", "corneal / small-nerve fiber repair narrative", "inflammation / tissue-protection discussion" ], "summary": "ARA-290 (cibinetide) is an erythropoietin-derived research peptide studied for small-fiber nerve pain without the intended blood-building action.", "search_blob": "ara-290 ara-290 cibinetide pyroglutamate helix b surface peptide phbsp phbsp pyroglutamate hbsp ara 290 ara290 helix b surface peptide pglu-glu-gln-leu-glu-arg-ala-leu-asn-ser-ser ara-290 ara 290 ara290 cibinetide phbsp pyroglutamate helix b surface peptide small fiber neuropathy (sfn) sarcoidosis-associated neuropathic pain diabetic peripheral neuropathy discussion neuropathic pain (burning, tingling, allodynia) corneal / small-nerve fiber repair narrative inflammation / tissue-protection discussion neuropathy discussion inflammation discussion recovery small fiber neuropathy (sfn) sarcoidosis-associated neuropathic pain diabetic peripheral neuropathy discussion neuropathic pain (burning, tingling, allodynia) corneal / small-nerve fiber repair narrative inflammation / tissue-protection discussion metabolic adjacency (hba1c / lipids in t2d trial) recovery and nerve-support stacks (community) disease-modification hope vs symptom-only relief debate small fiber neuropathy (sfn) sarcoidosis-associated neuropathic pain diabetic peripheral neuropathy discussion neuropathic pain (burning, tingling, allodynia) corneal / small-nerve fiber repair narrative inflammation / tissue-protection discussion ara-290 (cibinetide) is an erythropoietin-derived research peptide studied for small-fiber nerve pain without the intended blood-building action. one neuropathy writer reports relief around day 12, but later says it stopped helping after about seven months. that follow-up tempers the early positive log. ara-290, or cibinetide, is an epo-derived research peptide discussed for burning, tingling and reduced sensation from neuropathy. reports include relief, no benefit and painful flares. healing & repair peptide systemic systemic \u2014 sc or iv for innate-repair / neuropathic and inflammatory pathways; not a local joint depot or topical. systemic whole-body circulating", "legal_class": null }, { "id": 52, "slug": "vip", "name": "VIP", "aliases": [ "Vasoactive Intestinal Peptide", "Vasoactive Intestinal Polypeptide", "Aviptadil (pharmaceutical synthetic VIP)", "VIP nasal spray", "Intranasal VIP", "VIP-CIRS / Shoemaker VIP", "Invicorp component (aviptadil + phentolamine ED product \u2014 different use/route)" ], "type": "Peptide", "category": "Immune & neuropeptides", "goals_use_cases": [ "immune", "mold illness discussion", "inflammation discussion", "immune modulation (discussed)", "mold illness / biotoxin discussion", "CIRS / water-damaged building (WDB) protocol step (discussed)", "inflammation / innate immune calm (discussed)", "neuroimmune regulation (discussed)", "grey-matter / NeuroQuant recovery narratives (CIRS literature)", "pulmonary vascular / exercise PASP discussion", "low endogenous VIP / MSH biomarker framing", "post-exposure recovery narratives", "sleep / circadian adjacency in CIRS clusters", "pulmonary hypertension and ARDS research (Aviptadil \u2014 separate from CIRS nasal culture)", "erectile-dysfunction pharmaceutical adjacency (Invicorp aviptadil dose \u2014 not CIRS stack)" ], "delivery_methods": [ "nasal", "subcutaneous" ], "discussion_popularity": "Medium", "reach": "Mixed", "misspellings_search_terms": [ "vip", "Vasoactive Intestinal Peptide", "Vasoactive Intestinal Polypeptide", "Aviptadil (pharmaceutical synthetic VIP)", "VIP nasal spray", "Intranasal VIP", "immune modulation (discussed)", "mold illness / biotoxin discussion", "cirs / water-damaged building (wdb) protocol step (discussed)", "inflammation / innate immune calm (discussed)", "neuroimmune regulation (discussed)", "grey-matter / neuroquant recovery narratives (cirs literature)" ], "feel_search": [ "immune modulation (discussed)", "mold illness / biotoxin discussion", "cirs / water-damaged building (wdb) protocol step (discussed)", "inflammation / innate immune calm (discussed)", "neuroimmune regulation (discussed)", "grey-matter / neuroquant recovery narratives (cirs literature)" ], "summary": "VIP is vasoactive intestinal peptide, a natural 28-amino-acid signaling peptide; synthetic aviptadil is discussed in CIRS and other clinical contexts.", "search_blob": "vip vip vasoactive intestinal peptide vasoactive intestinal polypeptide aviptadil (pharmaceutical synthetic vip) vip nasal spray intranasal vip vip-cirs / shoemaker vip invicorp component (aviptadil + phentolamine ed product \u2014 different use/route) vip vasoactive intestinal peptide vasoactive intestinal polypeptide aviptadil (pharmaceutical synthetic vip) vip nasal spray intranasal vip immune modulation (discussed) mold illness / biotoxin discussion cirs / water-damaged building (wdb) protocol step (discussed) inflammation / innate immune calm (discussed) neuroimmune regulation (discussed) grey-matter / neuroquant recovery narratives (cirs literature) immune mold illness discussion inflammation discussion immune modulation (discussed) mold illness / biotoxin discussion cirs / water-damaged building (wdb) protocol step (discussed) inflammation / innate immune calm (discussed) neuroimmune regulation (discussed) grey-matter / neuroquant recovery narratives (cirs literature) pulmonary vascular / exercise pasp discussion low endogenous vip / msh biomarker framing post-exposure recovery narratives sleep / circadian adjacency in cirs clusters pulmonary hypertension and ards research (aviptadil \u2014 separate from cirs nasal culture) erectile-dysfunction pharmaceutical adjacency (invicorp aviptadil dose \u2014 not cirs stack) immune modulation (discussed) mold illness / biotoxin discussion cirs / water-damaged building (wdb) protocol step (discussed) inflammation / innate immune calm (discussed) neuroimmune regulation (discussed) grey-matter / neuroquant recovery narratives (cirs literature) vip is vasoactive intestinal peptide, a natural 28-amino-acid signaling peptide; synthetic aviptadil is discussed in cirs and other clinical contexts. some nasal-spray users describe better concentration; others initially report more anxiety, bloating, pain or feeling generally unwell. vip is a signaling peptide discussed in mold-illness and cirs communities for brain fog, energy and recovery. a small selected open-label cohort reported improvement, while community accounts include partial benefit, no change and substantial worsening. immune & neuropeptides peptide mixed mixed \u2014 nasal cirs use, systemic subq discussion, and inhaled or iv pharmaceutical research are distinct contexts. mixed local systemic", "legal_class": null }, { "id": 53, "slug": "larazotide", "name": "Larazotide", "aliases": [ "AT-1001", "Larazotide acetate", "AT1001", "AT 1001", "INN-202", "GGVLVQPG", "H-Gly-Gly-Val-Leu-Val-Gln-Pro-Gly-OH", "zonulin antagonist (discussion shorthand)", "tight-junction regulator peptide (discussion)" ], "type": "Peptide", "category": "Gut & inflammation peptides", "goals_use_cases": [ "recovery", "gut health", "tight junction discussion", "celiac adjacency discussion", "gut health / barrier integrity (discussed)", "tight junction / zonulin-pathway discussion", "celiac disease symptom adjacency (trial + community)", "intestinal permeability / \u201cleaky gut\u201d talk", "nonresponsive celiac on gluten-free diet (trial design)", "GI symptom support (bloating, pain, cramping domains \u2014 discussed)", "gluten-challenge protection talk (trial context)", "autoimmune adjacency (speculative community)", "post-viral / MIS-C / long-COVID gut-leak hypotheses (early clinical interest)", "stack partner with BPC-157 / KPV for multi-mechanism gut protocols" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Mixed", "misspellings_search_terms": [ "larazotide", "Larazotide acetate", "AT-1001", "AT1001", "AT 1001", "INN-202", "leaky gut", "tight junction", "bloating", "gluten", "gut trifecta", "before meals", "not a pin", "zonulin" ], "feel_search": [ "leaky gut", "tight junction", "bloating", "gluten", "gut trifecta", "before meals", "not a pin", "zonulin" ], "summary": "Larazotide acetate is an experimental oral peptide intended to regulate the gut barrier, studied in celiac disease and discussed for persistent gut symptoms.", "search_blob": "larazotide larazotide at-1001 larazotide acetate at1001 at 1001 inn-202 ggvlvqpg h-gly-gly-val-leu-val-gln-pro-gly-oh zonulin antagonist (discussion shorthand) tight-junction regulator peptide (discussion) larazotide larazotide acetate at-1001 at1001 at 1001 inn-202 leaky gut tight junction bloating gluten gut trifecta before meals not a pin zonulin recovery gut health tight junction discussion celiac adjacency discussion gut health / barrier integrity (discussed) tight junction / zonulin-pathway discussion celiac disease symptom adjacency (trial + community) intestinal permeability / \u201cleaky gut\u201d talk nonresponsive celiac on gluten-free diet (trial design) gi symptom support (bloating, pain, cramping domains \u2014 discussed) gluten-challenge protection talk (trial context) autoimmune adjacency (speculative community) post-viral / mis-c / long-covid gut-leak hypotheses (early clinical interest) stack partner with bpc-157 / kpv for multi-mechanism gut protocols leaky gut tight junction bloating gluten gut trifecta before meals not a pin zonulin larazotide acetate is an experimental oral peptide intended to regulate the gut barrier, studied in celiac disease and discussed for persistent gut symptoms. usually there is no stimulant-like sensation. some report less bloating or discomfort, while others notice little; one positive account later became hard to interpret after illness and treatment changes. larazotide is an oral peptide people look up for gut comfort. people report quieter bloating or less post-exposure anxiety. the 0.5 mg three-times-daily oral arm, given before meals, met the trial\u2019s primary placebo comparison; higher arms did not. that finding does not validate community products. larazotide is not an approved celiac drug. gut & inflammation peptides peptide mixed oral gut-barrier research, with before-meal use in trials. vendor injection charts do not match that clinical route. mixed local systemic", "legal_class": null }, { "id": 54, "slug": "humanin", "name": "Humanin", "aliases": [ "HN", "mitochondrial-derived peptide humanin", "MDP humanin", "MT-RNR2 peptide", "MTRNR2-encoded peptide", "HNG (S14G-humanin analog)", "S14G-HN", "S14G-humanin", "Humanin-G", "HNGF6A", "Colivelin (related potent derivative)", "MAPRGFSCLLLLTSEIDLPVKRRA" ], "type": "Peptide", "category": "Mitochondrial & metabolic peptides", "goals_use_cases": [ "longevity", "neuroprotection discussion", "metabolic health", "longevity / healthspan", "Alzheimer\u2019s / cognitive aging research interest", "insulin sensitivity (discussed)", "mitochondrial function / cytoprotection", "cardiovascular / ischemia research interest", "beta-cell survival / diabetes models", "anti-apoptotic cell-stress resilience", "healthy aging biomarker interest", "exercise\u2013mito peptide discussion" ], "delivery_methods": [ "subcutaneous", "nasal" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "humanin", "HN", "mitochondrial-derived peptide humanin", "MDP humanin", "MT-RNR2 peptide", "MTRNR2-encoded peptide", "longevity / healthspan", "neuroprotection discussion", "alzheimer\u2019s / cognitive aging research interest", "metabolic health", "insulin sensitivity (discussed)", "mitochondrial function / cytoprotection" ], "feel_search": [ "longevity / healthspan", "neuroprotection discussion", "alzheimer\u2019s / cognitive aging research interest", "metabolic health", "insulin sensitivity (discussed)", "mitochondrial function / cytoprotection" ], "summary": "Humanin is a mitochondrial-derived peptide studied for cellular stress protection; biohacker discussion focuses on aging, cognition and metabolic health.", "search_blob": "humanin humanin hn mitochondrial-derived peptide humanin mdp humanin mt-rnr2 peptide mtrnr2-encoded peptide hng (s14g-humanin analog) s14g-hn s14g-humanin humanin-g hngf6a colivelin (related potent derivative) maprgfsclllltseidlpvkrra humanin hn mitochondrial-derived peptide humanin mdp humanin mt-rnr2 peptide mtrnr2-encoded peptide longevity / healthspan neuroprotection discussion alzheimer\u2019s / cognitive aging research interest metabolic health insulin sensitivity (discussed) mitochondrial function / cytoprotection longevity neuroprotection discussion metabolic health longevity / healthspan alzheimer\u2019s / cognitive aging research interest insulin sensitivity (discussed) mitochondrial function / cytoprotection cardiovascular / ischemia research interest beta-cell survival / diabetes models anti-apoptotic cell-stress resilience healthy aging biomarker interest exercise\u2013mito peptide discussion longevity / healthspan neuroprotection discussion alzheimer\u2019s / cognitive aging research interest metabolic health insulin sensitivity (discussed) mitochondrial function / cytoprotection humanin is a mitochondrial-derived peptide studied for cellular stress protection; biohacker discussion focuses on aging, cognition and metabolic health. humanin is a mitochondrial-derived peptide studied for cellular stress protection and discussed for healthy aging. reports include possible sleep or anxiety changes and no noticeable effect; native humanin and hng are different molecules. mitochondrial & metabolic peptides peptide systemic systemic \u2014 circulating mitochondrial-derived signal with multi-organ research interest (brain, heart, pancreas/islets, endothelium, skeletal muscle, retina). systemic whole-body circulating", "legal_class": null }, { "id": 55, "slug": "foxo4-dri", "name": "FOXO4-DRI", "aliases": [ "FOXO4 D-Retro-Inverso", "proxofim (colloquial discussion)", "FOXO4 DRI", "FOX04-DRI", "FOXO4DRI", "Proxofim (vendor/colloquial discussion)", "FOXO4 interference peptide (DRI)", "FOXO4 D-retro-inverso peptide", "FOXO4-p53 interference peptide" ], "type": "Peptide", "category": "Senolytic research peptides", "goals_use_cases": [ "longevity", "senolytic discussion", "longevity / healthspan (discussed)", "senolytic / \u201czombie cell\u201d clearance discussion", "cellular senescence research", "inflammation / SASP reduction narratives", "chemotherapy-recovery models (preclinical)", "age-related testosterone / Leydig cell discussion (preclinical)", "cartilage / chondrocyte senescence research (in vitro human cells)", "endothelial / vascular aging research interest", "tissue homeostasis and fitness restoration (aged-mouse framing)", "hair/fur density lore from mouse coat recovery", "complement to small-molecule senolytics (D+Q, fisetin) in stack talk" ], "delivery_methods": [ "research injection discussion" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "foxo4-dri", "foxo4 dri", "foxo4dri", "FOXO4 D-Retro-Inverso", "FOX04-DRI", "Proxofim (vendor/colloquial discussion)", "longevity / healthspan (discussed)", "senolytic / \u201czombie cell\u201d clearance discussion", "cellular senescence research", "inflammation / sasp reduction narratives", "chemotherapy-recovery models (preclinical)", "age-related testosterone / leydig cell discussion (preclinical)" ], "feel_search": [ "longevity / healthspan (discussed)", "senolytic / \u201czombie cell\u201d clearance discussion", "cellular senescence research", "inflammation / sasp reduction narratives", "chemotherapy-recovery models (preclinical)", "age-related testosterone / leydig cell discussion (preclinical)" ], "summary": "FOXO4-DRI is an experimental peptide designed to kill senescent cells; longevity users discuss short self-experiments, with uncertain human benefit.", "search_blob": "foxo4-dri foxo4-dri foxo4 d-retro-inverso proxofim (colloquial discussion) foxo4 dri fox04-dri foxo4dri proxofim (vendor/colloquial discussion) foxo4 interference peptide (dri) foxo4 d-retro-inverso peptide foxo4-p53 interference peptide foxo4-dri foxo4 dri foxo4dri foxo4 d-retro-inverso fox04-dri proxofim (vendor/colloquial discussion) longevity / healthspan (discussed) senolytic / \u201czombie cell\u201d clearance discussion cellular senescence research inflammation / sasp reduction narratives chemotherapy-recovery models (preclinical) age-related testosterone / leydig cell discussion (preclinical) longevity senolytic discussion longevity / healthspan (discussed) senolytic / \u201czombie cell\u201d clearance discussion cellular senescence research inflammation / sasp reduction narratives chemotherapy-recovery models (preclinical) age-related testosterone / leydig cell discussion (preclinical) cartilage / chondrocyte senescence research (in vitro human cells) endothelial / vascular aging research interest tissue homeostasis and fitness restoration (aged-mouse framing) hair/fur density lore from mouse coat recovery complement to small-molecule senolytics (d+q, fisetin) in stack talk longevity / healthspan (discussed) senolytic / \u201czombie cell\u201d clearance discussion cellular senescence research inflammation / sasp reduction narratives chemotherapy-recovery models (preclinical) age-related testosterone / leydig cell discussion (preclinical) foxo4-dri is an experimental peptide designed to kill senescent cells; longevity users discuss short self-experiments, with uncertain human benefit. foxo4-dri is a peptide people look up for longevity. many short runs report nothing noticeable; product identity/purity is a huge confounder on expensive d-synthesis material. \u201cproxofim\u201d appears on some research-vendor listings for the same senolytic peptide concept \u2014 not a distinct clinical brand. senolytic research peptides peptide systemic systemic \u2014 designed to disrupt foxo4\u2013p53 survival signaling in senescent cells body-wide after parenteral exposure, not a local injury-site or cosmetic peptide. systemic whole-body circulating", "legal_class": null }, { "id": 56, "slug": "p21", "name": "P21", "aliases": [ "P021", "peptide 021 discussion", "Peptide 021", "Peptide 21", "P21 peptide", "P021 peptide", "CNTF-derived peptide P21", "CNTF small-molecule peptide mimetic P021", "Ac-DGGLAG-NH2 (adamantylated form)", "Ac-DGGL A G-NH2", "GLXC-21260 (catalog-style ID in some listings)", "CAS 1246751-68-7 (common registry listing)" ], "type": "Peptide", "category": "Cognitive / nootropic peptides", "goals_use_cases": [ "cognition", "neurogenesis discussion", "memory / learning (discussed)", "synaptic plasticity (preclinical)", "neuroprotection (preclinical)", "age-related cognitive interest", "Alzheimer\u2019s model research interest", "tau / amyloid pathology interest (animal AD models)", "Down syndrome model research interest (preclinical)", "brain fog / clarity without stimulant frame (community)", "proposed lasting plasticity versus immediate focus (community comparison)" ], "delivery_methods": [ "nasal", "subcutaneous" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "p21", "P021", "Peptide 021", "Peptide 21", "P21 peptide", "P021 peptide", "cognition", "neurogenesis discussion", "memory / learning (discussed)", "synaptic plasticity (preclinical)", "neuroprotection (preclinical)", "age-related cognitive interest" ], "feel_search": [ "cognition", "neurogenesis discussion", "memory / learning (discussed)", "synaptic plasticity (preclinical)", "neuroprotection (preclinical)", "age-related cognitive interest" ], "summary": "P21/P021 is an experimental CNTF-derived peptide mimetic discussed for memory and mental clarity; it is not the cell-cycle protein p21.", "search_blob": "p21 p21 p021 peptide 021 discussion peptide 021 peptide 21 p21 peptide p021 peptide cntf-derived peptide p21 cntf small-molecule peptide mimetic p021 ac-dgglag-nh2 (adamantylated form) ac-dggl a g-nh2 glxc-21260 (catalog-style id in some listings) cas 1246751-68-7 (common registry listing) p21 p021 peptide 021 peptide 21 p21 peptide p021 peptide cognition neurogenesis discussion memory / learning (discussed) synaptic plasticity (preclinical) neuroprotection (preclinical) age-related cognitive interest cognition neurogenesis discussion memory / learning (discussed) synaptic plasticity (preclinical) neuroprotection (preclinical) age-related cognitive interest alzheimer\u2019s model research interest tau / amyloid pathology interest (animal ad models) down syndrome model research interest (preclinical) brain fog / clarity without stimulant frame (community) proposed lasting plasticity versus immediate focus (community comparison) cognition neurogenesis discussion memory / learning (discussed) synaptic plasticity (preclinical) neuroprotection (preclinical) age-related cognitive interest p21/p021 is an experimental cntf-derived peptide mimetic discussed for memory and mental clarity; it is not the cell-cycle protein p21. some nasal users describe clearer thinking or calmer mood over weeks, while others notice little or fading benefit. an acute injection account described panic, so routes should not be pooled. p21 is an experimental peptide discussed for memory; it is unrelated to the p21 cell-cycle protein. accounts include clearer thinking, no benefit, mood or dream changes and adverse reactions. marketed as a \u201cstructural\u201d neurogenic nootropic from rodent dentate-gyrus, bdnf and synaptic-marker work; this does not establish human neurogenesis or exclude day-one effects. cognitive / nootropic peptides peptide systemic brain-focused research peptide \u2014 nasal, subq and oral reports do not establish targeted human brain delivery. systemic whole-body circulating", "legal_class": null }, { "id": 57, "slug": "cerebrolysin", "name": "Cerebrolysin", "aliases": [ "neuropeptide mixture", "FPF 1070", "FPF-1070", "FPF1070", "Cerebrolysin concentrate", "neuropeptide mixture (porcine)", "brain protein hydrolysate (Cerebrolysin)", "porcine brain-derived peptide preparation", "EVER Pharma Cerebrolysin", "Cerebrolysin\u00ae", "cerebroprotein hydrolysate (related class \u2014 not identical to branded Cerebrolysin)", "Renacenz (related cerebroprotein product discussions)" ], "type": "Peptide", "category": "Cognitive / nootropic peptides", "goals_use_cases": [ "cognition", "recovery", "neuroprotection discussion", "post-stroke discussion", "TBI recovery discussion", "dementia research interest", "vascular dementia discussion", "Alzheimer\u2019s / AD-type dementia discussion", "memory & learning (discussed)", "neuroplasticity discussion", "brain fog (anecdotal)", "mental clarity / deep work (community)", "performance continuity (cognitive)", "post-concussion / mild TBI community interest", "aging-brain repair narrative" ], "delivery_methods": [ "intramuscular", "IV" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "cerebrolysin", "FPF 1070", "FPF-1070", "FPF1070", "Cerebrolysin concentrate", "neuropeptide mixture (porcine)", "cognition", "neuroprotection discussion", "recovery", "post-stroke discussion", "tbi recovery discussion", "dementia research interest" ], "feel_search": [ "cognition", "neuroprotection discussion", "recovery", "post-stroke discussion", "tbi recovery discussion", "dementia research interest" ], "summary": "Cerebrolysin is an injectable mixture of peptides and amino acids used in some countries for neurological care and discussed by biohackers for cognition.", "search_blob": "cerebrolysin cerebrolysin neuropeptide mixture fpf 1070 fpf-1070 fpf1070 cerebrolysin concentrate neuropeptide mixture (porcine) brain protein hydrolysate (cerebrolysin) porcine brain-derived peptide preparation ever pharma cerebrolysin cerebrolysin\u00ae cerebroprotein hydrolysate (related class \u2014 not identical to branded cerebrolysin) renacenz (related cerebroprotein product discussions) cerebrolysin fpf 1070 fpf-1070 fpf1070 cerebrolysin concentrate neuropeptide mixture (porcine) cognition neuroprotection discussion recovery post-stroke discussion tbi recovery discussion dementia research interest cognition recovery neuroprotection discussion post-stroke discussion tbi recovery discussion dementia research interest vascular dementia discussion alzheimer\u2019s / ad-type dementia discussion memory & learning (discussed) neuroplasticity discussion brain fog (anecdotal) mental clarity / deep work (community) performance continuity (cognitive) post-concussion / mild tbi community interest aging-brain repair narrative cognition neuroprotection discussion recovery post-stroke discussion tbi recovery discussion dementia research interest cerebrolysin is an injectable mixture of peptides and amino acids used in some countries for neurological care and discussed by biohackers for cognition. a 20-day course log describes early well-being and vivid dreams, followed by fading euphoria and increasing brain fog. exercise and other supplements also changed. cerebrolysin is an injectable mixture of peptides and amino acids discussed for neurological recovery and cognition. reports include clearer thinking, no benefit, agitation, sleep changes and lingering fog. cognitive / nootropic peptides peptide systemic an im/iv porcine-brain peptide mixture with systemic exposure; not one receptor-specific peptide. systemic whole-body circulating", "legal_class": null }, { "id": 58, "slug": "noopept", "name": "Noopept", "aliases": [ "GVS-111", "omberacetam", "DVD-111", "SGS-111", "Omberacetam (INN)", "N-phenylacetyl-L-prolylglycine ethyl ester", "N-phenylacetylprolylglycine ethyl ester", "Benzylcarbonyl-Pro-Gly-OEt", "Noopept\u00ae", "\u041d\u043e\u043e\u043f\u0435\u043f\u0442" ], "type": "Non-peptide", "category": "Cognitive research compounds", "goals_use_cases": [ "cognition", "focus", "mood", "focus / attention", "memory / learning support (discussed)", "verbal fluency / word-finding (community)", "mental clarity / brain fog (discussed)", "mood / mild anxiolytic component (trial + community)", "study / deep-work performance", "neuroprotection discussion", "post-traumatic / vascular MCI discussion (Russian clinical history)", "vs-piracetam low-mg racetam-class alternative" ], "delivery_methods": [ "oral", "sublingual" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "noopept", "GVS-111", "DVD-111", "SGS-111", "omberacetam", "Omberacetam (INN)", "cognition", "focus / attention", "memory / learning support (discussed)", "verbal fluency / word-finding (community)", "mental clarity / brain fog (discussed)", "mood / mild anxiolytic component (trial + community)" ], "feel_search": [ "cognition", "focus / attention", "memory / learning support (discussed)", "verbal fluency / word-finding (community)", "mental clarity / brain fog (discussed)", "mood / mild anxiolytic component (trial + community)" ], "summary": "Noopept (omberacetam) is a synthetic peptide-derived nootropic, usually discussed for memory and focus at low oral milligram amounts.", "search_blob": "noopept noopept gvs-111 omberacetam dvd-111 sgs-111 omberacetam (inn) n-phenylacetyl-l-prolylglycine ethyl ester n-phenylacetylprolylglycine ethyl ester benzylcarbonyl-pro-gly-oet noopept\u00ae \u043d\u043e\u043e\u043f\u0435\u043f\u0442 noopept gvs-111 dvd-111 sgs-111 omberacetam omberacetam (inn) cognition focus / attention memory / learning support (discussed) verbal fluency / word-finding (community) mental clarity / brain fog (discussed) mood / mild anxiolytic component (trial + community) cognition focus mood focus / attention memory / learning support (discussed) verbal fluency / word-finding (community) mental clarity / brain fog (discussed) mood / mild anxiolytic component (trial + community) study / deep-work performance neuroprotection discussion post-traumatic / vascular mci discussion (russian clinical history) vs-piracetam low-mg racetam-class alternative cognition focus / attention memory / learning support (discussed) verbal fluency / word-finding (community) mental clarity / brain fog (discussed) mood / mild anxiolytic component (trial + community) noopept (omberacetam) is a synthetic peptide-derived nootropic, usually discussed for memory and focus at low oral milligram amounts. some describe clearer thinking, sensory vividness or easier focus; others notice nothing or discomfort. route, caffeine, other nootropics and sleep make comparisons difficult. noopept is a peptide-derived nootropic discussed for cognition. some report easier focus or word-finding; others describe no benefit, brain fog, anxiety or disrupted sleep. route, caffeine and other nootropics complicate comparisons. \u201c~1000\u00d7 more potent than piracetam\u201d is a dose-scale slogan (tens of mg vs grams) \u2014 not a proven 1000\u00d7 efficacy multiplier in humans. cognitive research compounds non-peptide systemic cns-oriented small molecule used mainly by oral or sublingual routes; intranasal use is a minority experiment. systemic whole-body circulating", "legal_class": null }, { "id": 59, "slug": "methylene-blue", "name": "Methylene Blue", "aliases": [ "MB", "methylthioninium chloride", "USP methylene blue discussion", "methylthioninium", "USP methylene blue", "pharmaceutical-grade methylene blue", "ProvayBlue (clinical IV brand context)", "Proveblue (clinical brand context)", "methylene blue USP", "MB drops / oral solution (community form)", "LMTM / LMTX / TRx0237 / hydromethylthionine (related tau-aggregation derivative \u2014 not the same consumer MB)", "Rember (older methylthioninium chloride AD program context)" ], "type": "Non-peptide", "category": "Mitochondrial & metabolic compounds", "goals_use_cases": [ "focus", "cognition", "mitochondrial discussion", "mood", "cognition / focus / mental clarity (discussed)", "memory retrieval and short-term memory (small human imaging work)", "mitochondrial electron-transport / cellular energy discussion", "mood / residual bipolar depression adjunct research (historical)", "longevity / healthy-aging mito tonic talk", "neuroprotection and neurodegenerative model interest", "energy / mental fatigue / brain-fog narratives", "red-light / photobiomodulation stack culture", "clinical methemoglobinemia (FDA-approved IV indication)", "ICU / perioperative vasoplegia and surgical dye contexts (hospital only)", "PTSD extinction / exposure-therapy adjunct research interest (historical trials)" ], "delivery_methods": [ "oral", "IV" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "methylene-blue", "methylene blue", "methyleneblue", "MB", "methylthioninium chloride", "methylthioninium", "brain fog", "focus", "blue urine", "mito", "G6PD", "SSRI", "USP", "aquarium" ], "feel_search": [ "brain fog", "focus", "blue urine", "mito", "methylene blue", "G6PD", "SSRI", "aquarium" ], "summary": "Methylene blue is a dye and medicine, also used experimentally in low oral amounts for focus and energy.", "search_blob": "methylene blue methylene-blue mb methylthioninium chloride usp methylene blue discussion methylthioninium usp methylene blue pharmaceutical-grade methylene blue provayblue (clinical iv brand context) proveblue (clinical brand context) methylene blue usp mb drops / oral solution (community form) lmtm / lmtx / trx0237 / hydromethylthionine (related tau-aggregation derivative \u2014 not the same consumer mb) rember (older methylthioninium chloride ad program context) methylene-blue methylene blue methyleneblue mb methylthioninium chloride methylthioninium brain fog focus blue urine mito g6pd ssri usp aquarium focus cognition mitochondrial discussion mood cognition / focus / mental clarity (discussed) memory retrieval and short-term memory (small human imaging work) mitochondrial electron-transport / cellular energy discussion mood / residual bipolar depression adjunct research (historical) longevity / healthy-aging mito tonic talk neuroprotection and neurodegenerative model interest energy / mental fatigue / brain-fog narratives red-light / photobiomodulation stack culture clinical methemoglobinemia (fda-approved iv indication) icu / perioperative vasoplegia and surgical dye contexts (hospital only) ptsd extinction / exposure-therapy adjunct research interest (historical trials) brain fog focus blue urine mito methylene blue g6pd ssri aquarium methylene blue is a dye and medicine, also used experimentally in low oral amounts for focus and energy. methylene blue is an oral compound people look up for focus and mental energy. people post about sharper focus, less fog, and more daytime energy. accounts pair oral use with red light, coq10 or an nad precursor, making effects harder to attribute. reported benefit coexists with nonresponse, headaches and sleep disruption. mitochondrial & metabolic compounds non-peptide systemic systemic dye with oral and intravenous exposure; clinical methemoglobinemia use and community nootropic use are different evidence contexts. systemic whole-body circulating", "legal_class": null }, { "id": 60, "slug": "metformin", "name": "Metformin", "aliases": [ "Glucophage", "metformin HCl", "Glucophage XR", "metformin hydrochloride", "Fortamet", "Glumetza", "Riomet", "metformin IR", "metformin XR / ER / SR", "metformin DR (delayed-release research formulations)", "dimethylbiguanide (class/historical)", "biguanide (class)" ], "type": "Non-peptide", "category": "Metabolic & longevity adjacents", "goals_use_cases": [ "metabolic health", "longevity", "glucose", "fat loss adjacency", "longevity / geroscience baseline", "glucose / HbA1c control", "insulin sensitivity", "type 2 diabetes (clinical context)", "prediabetes / diabetes-delay discussion (DPP)", "PCOS / insulin-resistance narratives", "fat-loss / recomp adjacency (mild)", "AMPK / nutrient-sensing interest", "bodybuilding cut / insulin-partitioning talk", "CR-mimetic framing", "cancer-risk observational interest" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "metformin", "Glucophage", "Glucophage XR", "metformin HCl", "metformin hydrochloride", "Fortamet", "TAME", "longevity metformin", "glucophage xr", "metabolic health", "longevity / geroscience baseline", "glucose / hba1c control", "insulin sensitivity", "type 2 diabetes (clinical context)", "prediabetes / diabetes-delay discussion (dpp)" ], "feel_search": [ "metabolic health", "longevity / geroscience baseline", "glucose / hba1c control", "insulin sensitivity", "type 2 diabetes (clinical context)", "prediabetes / diabetes-delay discussion (dpp)" ], "summary": "Metformin is an oral biguanide medicine for glucose control, also discussed in PCOS and longevity; immediate-release and extended-release forms can feel different.", "search_blob": "metformin metformin glucophage metformin hcl glucophage xr metformin hydrochloride fortamet glumetza riomet metformin ir metformin xr / er / sr metformin dr (delayed-release research formulations) dimethylbiguanide (class/historical) biguanide (class) metformin glucophage glucophage xr metformin hcl metformin hydrochloride fortamet tame longevity metformin glucophage xr metabolic health longevity / geroscience baseline glucose / hba1c control insulin sensitivity type 2 diabetes (clinical context) prediabetes / diabetes-delay discussion (dpp) metabolic health longevity glucose fat loss adjacency longevity / geroscience baseline glucose / hba1c control insulin sensitivity type 2 diabetes (clinical context) prediabetes / diabetes-delay discussion (dpp) pcos / insulin-resistance narratives fat-loss / recomp adjacency (mild) ampk / nutrient-sensing interest bodybuilding cut / insulin-partitioning talk cr-mimetic framing cancer-risk observational interest metabolic health longevity / geroscience baseline glucose / hba1c control insulin sensitivity type 2 diabetes (clinical context) prediabetes / diabetes-delay discussion (dpp) metformin is an oral biguanide medicine for glucose control, also discussed in pcos and longevity; immediate-release and extended-release forms can feel different. early experiences can involve diarrhea or nausea, but some feel mainly fatigue and others little discomfort. users in the reviewed thread often preferred extended release, though it did not eliminate early side effects for everyone. metformin is an oral prescription medicine for glucose control, also discussed for pcos and longevity. people report subtle or absent felt benefits alongside gi symptoms and fatigue; healthy-person life extension is not established. metabolic & longevity adjacents non-peptide systemic systemic \u2014 oral biguanide with whole-body glucose and nutrient-sensing effects (liver glucose output, insulin sensitivity, gut/incretin pathways). systemic whole-body circulating", "legal_class": null }, { "id": 61, "slug": "enclomiphene", "name": "Enclomiphene", "aliases": [ "Androxal-class discussion", "trans-clomiphene", "Enclomiphene citrate", "Enclomifene (INN-style spelling)", "Androxal (Repros development designation; not marketed)", "EnCyzix (EU development designation; not authorized)", "Enclomiphene HCl (compounded salt discussion)", "EC / enclo (forum shorthand)" ], "type": "Non-peptide", "category": "Hormone modulators", "goals_use_cases": [ "hormone axis", "libido", "fertility discussion", "muscle preservation", "secondary hypogonadism discussion", "PCT / post-cycle talk", "TRT alternative (discussed)", "energy / vitality (discussed)", "post-TRT restart / HPTA recovery talk", "sperm-parameter preservation vs exogenous T" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "enclomiphene", "Enclomiphene citrate", "Enclomifene (INN-style spelling)", "trans-clomiphene", "Androxal (Repros development designation; not marketed)", "EnCyzix (EU development designation; not authorized)", "low t", "libido", "pct", "clomid" ], "feel_search": [ "low t", "libido", "pct", "clomid" ], "summary": "Enclomiphene is the trans isomer of clomiphene, an oral selective estrogen receptor modulator discussed for raising the body\u2019s own testosterone.", "search_blob": "enclomiphene enclomiphene androxal-class discussion trans-clomiphene enclomiphene citrate enclomifene (inn-style spelling) androxal (repros development designation; not marketed) encyzix (eu development designation; not authorized) enclomiphene hcl (compounded salt discussion) ec / enclo (forum shorthand) enclomiphene enclomiphene citrate enclomifene (inn-style spelling) trans-clomiphene androxal (repros development designation; not marketed) encyzix (eu development designation; not authorized) low t libido pct clomid hormone axis libido fertility discussion muscle preservation secondary hypogonadism discussion pct / post-cycle talk trt alternative (discussed) energy / vitality (discussed) post-trt restart / hpta recovery talk sperm-parameter preservation vs exogenous t low t libido pct clomid enclomiphene is the trans isomer of clomiphene, an oral selective estrogen receptor modulator discussed for raising the body\u2019s own testosterone. one early user reports gym recovery and fullness, but libido remains mixed. they also take tongkat ali and lack a recent untreated hormone baseline. enclomiphene is an oral serm discussed for raising the body's own testosterone. some report better energy or libido; others feel no better despite higher laboratory values. preserved sperm measures do not guarantee fertility. clinic accounts often describe 12.5 mg daily, alongside other amounts and frequencies. visual symptoms, mood changes and lost libido remain part of the reports. hormone modulators non-peptide systemic systemic \u2014 oral serm (pure trans isomer of clomiphene); blocks central estrogen feedback so lh/fsh and endogenous testicular testosterone rise axis-wide. systemic whole-body circulating", "legal_class": null }, { "id": 62, "slug": "rad-140", "name": "RAD-140", "aliases": [ "Testolone", "RAD140", "RAD 140", "Vosilasarm (INN / development naming)", "EP0062 (reformulated clinical code)", "Testalone (common misspelling in literature and forums)", "Radius RAD140 (developer-adjacent search string)" ], "type": "Non-peptide", "category": "SARMs (adjacent discourse)", "goals_use_cases": [ "muscle growth", "performance", "fat loss adjacency", "strength", "body recomposition", "lean mass retention (discussed)", "bulking (community framing)", "cutting with muscle hold (discussed)", "dry / dense look vs wetter orals (forum typology)", "neuroprotection research interest (animal / in-vitro, not gym use)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "rad-140", "rad 140", "rad140", "Testolone", "Vosilasarm (INN / development naming)", "EP0062 (reformulated clinical code)", "strength", "recomp", "suppression", "sarm", "testolone" ], "feel_search": [ "strength", "recomp", "suppression", "sarm", "testolone" ], "summary": "RAD-140 (Testolone/vosilasarm) is an investigational oral nonsteroidal SARM acting on androgen receptors, discussed for muscle and strength.", "search_blob": "rad-140 rad-140 testolone rad140 rad 140 vosilasarm (inn / development naming) ep0062 (reformulated clinical code) testalone (common misspelling in literature and forums) radius rad140 (developer-adjacent search string) rad-140 rad 140 rad140 testolone vosilasarm (inn / development naming) ep0062 (reformulated clinical code) strength recomp suppression sarm testolone muscle growth performance fat loss adjacency strength body recomposition lean mass retention (discussed) bulking (community framing) cutting with muscle hold (discussed) dry / dense look vs wetter orals (forum typology) neuroprotection research interest (animal / in-vitro, not gym use) strength recomp suppression sarm testolone rad-140 (testolone/vosilasarm) is an investigational oral nonsteroidal sarm acting on androgen receptors, discussed for muscle and strength. one cut-phase user reported strength gains with more aggression and restless sleep, followed by lower drive and slower recovery after stopping. rad-140 is an investigational oral sarm discussed for muscle and strength. some report stronger lifts or retained strength while losing weight, but diet and training complicate attribution. not a legal supplement. reports include hormone suppression, disturbed sleep and liver-enzyme elevation despite feeling well. sarms (adjacent discourse) non-peptide systemic systemic oral sarm \u2014 whole-body exposure with muscle/bone-biased ar agonism talk; not a local inject and not a peptide. systemic whole-body circulating", "legal_class": null }, { "id": 63, "slug": "lgd-4033", "name": "LGD-4033", "aliases": [ "Ligandrol", "VK5211 discussion", "LGD", "VK5211", "VK-5211", "LGD4033", "LGD 4033", "Anabolicum", "LGD4033 (Ligandrol)" ], "type": "Non-peptide", "category": "SARMs (adjacent discourse)", "goals_use_cases": [ "muscle", "muscle growth", "performance", "lean mass / muscle growth (primary community use)", "strength and compound-lift progression (discussed)", "performance / training quality", "body recomposition (muscle-hold + fat-loss phases, discussed)", "bulking phases (community \u201charder oral SARM\u201d framing)", "recovery continuity during hard training blocks (discussed)", "clinical-adjacent muscle-wasting / hip-fracture recovery research (VK5211; not physique approval)", "bone / osteosarcopenia research interest (developmental history)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "lgd-4033", "lgd 4033", "lgd4033", "Ligandrol", "VK5211", "VK-5211", "lean mass / muscle growth (primary community use)", "strength and compound-lift progression (discussed)", "performance / training quality", "body recomposition (muscle-hold + fat-loss phases, discussed)", "bulking phases (community \u201charder oral sarm\u201d framing)", "recovery continuity during hard training blocks (discussed)" ], "feel_search": [ "lean mass / muscle growth (primary community use)", "strength and compound-lift progression (discussed)", "performance / training quality", "body recomposition (muscle-hold + fat-loss phases, discussed)", "bulking phases (community \u201charder oral sarm\u201d framing)", "recovery continuity during hard training blocks (discussed)" ], "summary": "LGD-4033 (Ligandrol/VK5211) is an experimental oral SARM, discussed for muscle and strength; it is not the same drug as LGD-3303.", "search_blob": "lgd-4033 lgd-4033 ligandrol vk5211 discussion lgd vk5211 vk-5211 lgd4033 lgd 4033 anabolicum lgd4033 (ligandrol) lgd-4033 lgd 4033 lgd4033 ligandrol vk5211 vk-5211 lean mass / muscle growth (primary community use) strength and compound-lift progression (discussed) performance / training quality body recomposition (muscle-hold + fat-loss phases, discussed) bulking phases (community \u201charder oral sarm\u201d framing) recovery continuity during hard training blocks (discussed) muscle muscle growth performance lean mass / muscle growth (primary community use) strength and compound-lift progression (discussed) performance / training quality body recomposition (muscle-hold + fat-loss phases, discussed) bulking phases (community \u201charder oral sarm\u201d framing) recovery continuity during hard training blocks (discussed) clinical-adjacent muscle-wasting / hip-fracture recovery research (vk5211; not physique approval) bone / osteosarcopenia research interest (developmental history) lean mass / muscle growth (primary community use) strength and compound-lift progression (discussed) performance / training quality body recomposition (muscle-hold + fat-loss phases, discussed) bulking phases (community \u201charder oral sarm\u201d framing) recovery continuity during hard training blocks (discussed) lgd-4033 (ligandrol/vk5211) is an experimental oral sarm, discussed for muscle and strength; it is not the same drug as lgd-3303. one 11-day report described better lifts and recovery but also nausea, night sweats, flatter mood and worse aerobic capacity, leading the author to stop. a fuller look may partly reflect water. lgd-4033 is an experimental sarm discussed for muscle and strength. reports include better lifts, little change, fatigue, low libido and adverse laboratory changes; a fuller appearance can include water. sarms (adjacent discourse) non-peptide systemic systemic oral sarm \u2014 whole-body androgen-receptor signaling with tissue-selective framing (muscle/bone favored over prostate in preclinical models). systemic whole-body circulating", "legal_class": null }, { "id": 64, "slug": "ostarine", "name": "Ostarine", "aliases": [ "MK-2866", "Enobosarm", "GTx-024", "S-22", "OTR-AC", "VERU-024", "MK2866", "Enobosarm (INN / clinical naming)" ], "type": "Non-peptide", "category": "SARMs (adjacent discourse)", "goals_use_cases": [ "muscle growth", "recomposition", "performance", "lean mass preservation (discussed)", "cutting / anti-catabolism (discussed)", "strength continuity (discussed)", "body composition", "injury-return training (discussed)", "GLP-1 lean-mass hold adjacency (trial + discussion)", "beginner SARM entry point (community framing)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "ostarine", "MK-2866", "Enobosarm", "GTx-024", "S-22", "OTR-AC", "recomp", "sarm", "suppression", "enobosarm" ], "feel_search": [ "recomp", "sarm", "suppression", "enobosarm" ], "summary": "Ostarine (enobosarm) is an experimental oral SARM discussed for retaining muscle during cuts and improving training recovery.", "search_blob": "ostarine ostarine mk-2866 enobosarm gtx-024 s-22 otr-ac veru-024 mk2866 enobosarm (inn / clinical naming) ostarine mk-2866 enobosarm gtx-024 s-22 otr-ac recomp sarm suppression enobosarm muscle growth recomposition performance lean mass preservation (discussed) cutting / anti-catabolism (discussed) strength continuity (discussed) body composition injury-return training (discussed) glp-1 lean-mass hold adjacency (trial + discussion) beginner sarm entry point (community framing) recomp sarm suppression enobosarm ostarine (enobosarm) is an experimental oral sarm discussed for retaining muscle during cuts and improving training recovery. some describe better strength retention or recovery, others little effect. fatigue, mood changes and other symptoms can appear during longer runs, especially in changing stacks. ostarine is an experimental oral sarm discussed for muscle retention. some report maintaining strength while dieting or recovering better; others notice little benefit or judge fatigue and other unwanted effects worse than the gains. several muscle-wasting studies used 1 or 3 mg daily; recreational charts often describe substantially higher amounts. these are different populations and evidence contexts. sarms (adjacent discourse) non-peptide systemic systemic oral sarm: whole-body androgen-receptor effects, with muscle/bone selectivity claims\u2014not a locally targeted injection. systemic whole-body circulating", "legal_class": null }, { "id": 65, "slug": "cardarine", "name": "Cardarine", "aliases": [ "GW501516", "GW1516", "Endurobol", "GW-501516", "GW 501516", "GW-1516", "GW 1516", "GW-501,516", "GSK-516", "Cardarine (Endurobol)" ], "type": "Non-peptide", "category": "Metabolic research compounds", "goals_use_cases": [ "endurance", "fat loss", "performance", "lipid profile (discussed)", "metabolic research", "cardio capacity (discussed)", "body recomposition (discussed)", "fatty-acid oxidation (discussed)", "contest / race prep cardio assist (discussed)", "Tren cardio offset (discussed)", "HDL support talk in PED users (discussed)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "cardarine", "GW501516", "GW-501516", "GW 501516", "GW1516", "GW-1516", "endurance", "cardio", "zone 2", "cancer scare", "not a SARM", "lipids", "HDL", "pre cardio", "WADA", "third lung" ], "feel_search": [ "endurance", "cardio", "zone 2", "cancer scare", "not a SARM", "lipids", "HDL", "pre cardio", "WADA", "third lung" ], "summary": "Cardarine (GW501516) is a non-peptide PPAR\u03b4 agonist investigated for metabolism and discussed for endurance; it is not a SARM.", "search_blob": "cardarine cardarine gw501516 gw1516 endurobol gw-501516 gw 501516 gw-1516 gw 1516 gw-501,516 gsk-516 cardarine (endurobol) cardarine gw501516 gw-501516 gw 501516 gw1516 gw-1516 endurance cardio zone 2 cancer scare not a sarm lipids hdl pre cardio wada third lung endurance fat loss performance lipid profile (discussed) metabolic research cardio capacity (discussed) body recomposition (discussed) fatty-acid oxidation (discussed) contest / race prep cardio assist (discussed) tren cardio offset (discussed) hdl support talk in ped users (discussed) endurance cardio zone 2 cancer scare not a sarm lipids hdl pre cardio wada third lung cardarine (gw501516) is a non-peptide ppar\u03b4 agonist investigated for metabolism and discussed for endurance; it is not a sarm. a runner\u2019s log reports no clear endurance or heart-rate benefit after about two weeks, despite pushing training. minor fitness gains were attributed to the training plan. cardarine is an experimental oral compound discussed for endurance. some 2026 diaries describe easier incline walks or race training, while other accounts report no benefit; animal tumor findings remain a major concern. not a sarm. the rodent cancer story is why careful threads stay wary. metabolic research compounds non-peptide systemic systemic \u2014 oral gw501516 is a ppar\u03b4 agonist, not a sarm; endurance and lipid discussion carries an unresolved rodent tumor warning. systemic whole-body circulating", "legal_class": null }, { "id": 66, "slug": "sr9009", "name": "SR9009", "aliases": [ "Stenabolic", "SR-9009", "SR 9009", "REV-ERB agonist SR9009", "Rev-ErbA agonist SR9009", "Scripps REV-ERB ligand SR9009" ], "type": "Non-peptide", "category": "Metabolic research compounds", "goals_use_cases": [ "endurance", "fat loss", "performance", "metabolic research", "mitochondrial support (discussed)", "body composition", "cardio capacity (discussed)", "lipid markers (preclinical discussion)", "exercise-mimetic research talk", "cut-phase conditioning" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "sr9009", "Stenabolic", "SR-9009", "SR 9009", "REV-ERB agonist SR9009", "Rev-ErbA agonist SR9009", "endurance", "fat loss", "performance", "metabolic research", "mitochondrial support (discussed)", "body composition" ], "feel_search": [ "endurance", "fat loss", "performance", "metabolic research", "mitochondrial support (discussed)", "body composition" ], "summary": "SR9009, nicknamed Stenabolic, is an experimental small-molecule REV-ERB receptor agonist discussed for metabolism and endurance.", "search_blob": "sr9009 sr9009 stenabolic sr-9009 sr 9009 rev-erb agonist sr9009 rev-erba agonist sr9009 scripps rev-erb ligand sr9009 sr9009 stenabolic sr-9009 sr 9009 rev-erb agonist sr9009 rev-erba agonist sr9009 endurance fat loss performance metabolic research mitochondrial support (discussed) body composition endurance fat loss performance metabolic research mitochondrial support (discussed) body composition cardio capacity (discussed) lipid markers (preclinical discussion) exercise-mimetic research talk cut-phase conditioning endurance fat loss performance metabolic research mitochondrial support (discussed) body composition sr9009, nicknamed stenabolic, is an experimental small-molecule rev-erb receptor agonist discussed for metabolism and endurance. the thread includes no effect, good sleep during a busy stacked regimen, and warmth with poorer sleep in another account. sr9009 is an experimental small molecule discussed for endurance and metabolism. reports include more energy, no change, lethargy, warmth and disturbed sleep; oral and other-route experiments do not establish equivalent exposure. metabolic research compounds non-peptide systemic systemic \u2014 experimental rev-erb ligand studied in whole-body circadian, metabolic and skeletal-muscle programs; not a peptide. systemic whole-body circulating", "legal_class": null }, { "id": 68, "slug": "survodutide", "name": "Survodutide", "aliases": [ "BI 456906", "glucagon/GLP-1 dual agonist discussion", "BI456906", "BI-456906", "glucagon/GLP-1 dual agonist", "GCGR/GLP-1R dual agonist", "Zealand/Boehringer dual agonist" ], "type": "Peptide", "category": "Metabolic / GLP-1 class", "goals_use_cases": [ "fat loss", "metabolic health", "liver fat discussion", "liver fat / MASLD discussion", "MASH / fibrosis research interest", "appetite control", "body composition (fat vs lean discussion)", "obesity management research", "cardiometabolic risk discussion", "visceral fat reduction (trial imaging)", "type 2 diabetes weight/glucose research (SYNCHRONIZE-2 program)" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "survodutide", "BI 456906", "BI456906", "BI-456906", "glucagon/GLP-1 dual agonist", "GCGR/GLP-1R dual agonist", "fat loss", "metabolic health", "liver fat / masld discussion", "mash / fibrosis research interest", "appetite control", "body composition (fat vs lean discussion)" ], "feel_search": [ "fat loss", "metabolic health", "liver fat / masld discussion", "mash / fibrosis research interest", "appetite control", "body composition (fat vs lean discussion)" ], "summary": "Survodutide (BI 456906) is an investigational peptide activating GLP-1 and glucagon receptors, studied for obesity and liver disease.", "search_blob": "survodutide survodutide bi 456906 glucagon/glp-1 dual agonist discussion bi456906 bi-456906 glucagon/glp-1 dual agonist gcgr/glp-1r dual agonist zealand/boehringer dual agonist survodutide bi 456906 bi456906 bi-456906 glucagon/glp-1 dual agonist gcgr/glp-1r dual agonist fat loss metabolic health liver fat / masld discussion mash / fibrosis research interest appetite control body composition (fat vs lean discussion) fat loss metabolic health liver fat discussion liver fat / masld discussion mash / fibrosis research interest appetite control body composition (fat vs lean discussion) obesity management research cardiometabolic risk discussion visceral fat reduction (trial imaging) type 2 diabetes weight/glucose research (synchronize-2 program) fat loss metabolic health liver fat / masld discussion mash / fibrosis research interest appetite control body composition (fat vs lean discussion) survodutide (bi 456906) is an investigational peptide activating glp-1 and glucagon receptors, studied for obesity and liver disease. some users combining it with tirzepatide describe more energy and quieter appetite; a blinded trial user felt no difference after stopping. survodutide is an investigational glp-1/glucagon peptide discussed for weight and liver-fat changes. sparse reports include quieter appetite, little change and fatigue; many also involve tirzepatide. direct self-reports are sparse. much dose discussion repeats trial charts, while several personal accounts also involve tirzepatide and cannot isolate survodutide. metabolic / glp-1 class peptide systemic systemic \u2014 once-weekly glucagon/glp-1 dual agonist for whole-body appetite, weight, energy-expenditure, and hepatic fat effects. systemic whole-body circulating", "legal_class": null }, { "id": 69, "slug": "mazdutide", "name": "Mazdutide", "aliases": [ "IBI362", "LY3305677 discussion", "IBI-362", "LY3305677", "LY-3305677", "OXM3 (development / oxyntomodulin-analog discussions)", "Xinermei", "\u4fe1\u8bfa\u7f8e (China brand name)", "GLP-1/glucagon dual agonist", "GCG/GLP-1 dual agonist", "mazdutide peptide", "Mezdutide (common misspelling in dose lists)" ], "type": "Peptide", "category": "Metabolic / GLP-1 class", "goals_use_cases": [ "fat loss", "metabolic health", "fat loss / chronic weight management", "appetite control / food-noise reduction", "glycemic control in type 2 diabetes (China-approved indication + DREAMS program)", "liver fat / MAFLD reduction (trial + GLORY-3 vs sema design)", "waist circumference and cardiometabolic markers (BP, lipids, uric acid)", "obesity research (moderate-to-severe / high-dose 9 mg program)", "type 2 diabetes research (China NMPA approved; Western still investigational)", "energy-expenditure / \u201cglucagon arm burns\u201d framing (mechanistic + community lore)", "gray-market dual-agonist alternative when sema/tirz access is constrained (community talk \u2014 not endorsement)" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "mazdutide", "IBI362", "IBI-362", "LY3305677", "LY-3305677", "OXM3 (development / oxyntomodulin-analog discussions)", "fat loss / chronic weight management", "appetite control / food-noise reduction", "metabolic health", "glycemic control in type 2 diabetes (china-approved indication + dreams program)", "liver fat / mafld reduction (trial + glory-3 vs sema design)", "waist circumference and cardiometabolic markers (bp, lipids, uric acid)" ], "feel_search": [ "fat loss / chronic weight management", "appetite control / food-noise reduction", "metabolic health", "glycemic control in type 2 diabetes (china-approved indication + dreams program)", "liver fat / mafld reduction (trial + glory-3 vs sema design)", "waist circumference and cardiometabolic markers (bp, lipids, uric acid)" ], "summary": "Mazdutide is a dual GLP-1/glucagon receptor agonist peptide developed for weight and glucose management, distinct from tirzepatide\u2019s receptor combination.", "search_blob": "mazdutide mazdutide ibi362 ly3305677 discussion ibi-362 ly3305677 ly-3305677 oxm3 (development / oxyntomodulin-analog discussions) xinermei \u4fe1\u8bfa\u7f8e (china brand name) glp-1/glucagon dual agonist gcg/glp-1 dual agonist mazdutide peptide mezdutide (common misspelling in dose lists) mazdutide ibi362 ibi-362 ly3305677 ly-3305677 oxm3 (development / oxyntomodulin-analog discussions) fat loss / chronic weight management appetite control / food-noise reduction metabolic health glycemic control in type 2 diabetes (china-approved indication + dreams program) liver fat / mafld reduction (trial + glory-3 vs sema design) waist circumference and cardiometabolic markers (bp, lipids, uric acid) fat loss metabolic health fat loss / chronic weight management appetite control / food-noise reduction glycemic control in type 2 diabetes (china-approved indication + dreams program) liver fat / mafld reduction (trial + glory-3 vs sema design) waist circumference and cardiometabolic markers (bp, lipids, uric acid) obesity research (moderate-to-severe / high-dose 9 mg program) type 2 diabetes research (china nmpa approved; western still investigational) energy-expenditure / \u201cglucagon arm burns\u201d framing (mechanistic + community lore) gray-market dual-agonist alternative when sema/tirz access is constrained (community talk \u2014 not endorsement) fat loss / chronic weight management appetite control / food-noise reduction metabolic health glycemic control in type 2 diabetes (china-approved indication + dreams program) liver fat / mafld reduction (trial + glory-3 vs sema design) waist circumference and cardiometabolic markers (bp, lipids, uric acid) mazdutide is a dual glp-1/glucagon receptor agonist peptide developed for weight and glucose management, distinct from tirzepatide\u2019s receptor combination. mazdutide is a peptide people look up for fat loss and appetite. first appetite drop and early fullness common; nausea/loose stools often appear after the first 1\u20132 injections. metabolic / glp-1 class peptide systemic systemic \u2014 a once-weekly glp-1/glucagon dual agonist studied for appetite, weight, glucose and liver-metabolic effects. systemic whole-body circulating", "legal_class": null }, { "id": 70, "slug": "orforglipron", "name": "Orforglipron", "aliases": [ "LY3502970", "oral non-peptide GLP-1 agonist", "Foundayo (branded oral orforglipron \u2014 weight indication discussion)", "Oral non-peptide GLP-1 agonist", "Oral small-molecule GLP-1 RA", "Lilly oral GLP-1 (discussion shorthand)", "Orforglipron pill (forum shorthand)", "Orf / orfor (forum shorthand)" ], "type": "Non-peptide", "category": "Metabolic / GLP-1 class", "goals_use_cases": [ "fat loss", "appetite control", "glucose", "fat loss / obesity weight management", "appetite control / food-noise reduction", "glucose / glycemic discussion (T2D programs)", "weight management without injections", "metabolic / cardiometabolic health markers", "type 2 diabetes\u2013adjacent research and ACHIEVE program interest", "oral switch / maintenance after injectable incretins (ATTAIN-MAINTAIN)", "needle-averse GLP-1 access interest", "primary-care scalable oral GLP-1 talk" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "orforglipron", "LY3502970", "Foundayo (branded oral orforglipron \u2014 weight indication discussion)", "Oral non-peptide GLP-1 agonist", "Oral small-molecule GLP-1 RA", "Lilly oral GLP-1 (discussion shorthand)", "Foundayo", "oral GLP-1", "food noise", "nausea", "any time", "Rybelsus", "oral Wegovy", "switch", "hair loss", "foundayo", "rybelsus", "oral wegovy", "pill" ], "feel_search": [ "foundayo", "oral GLP-1", "food noise", "nausea", "any time", "rybelsus", "oral wegovy", "switch", "hair loss", "pill" ], "summary": "Orforglipron is a non-peptide GLP-1 pill used for weight management; people look it up for reduced appetite without injections.", "search_blob": "orforglipron orforglipron ly3502970 oral non-peptide glp-1 agonist foundayo (branded oral orforglipron \u2014 weight indication discussion) oral non-peptide glp-1 agonist oral small-molecule glp-1 ra lilly oral glp-1 (discussion shorthand) orforglipron pill (forum shorthand) orf / orfor (forum shorthand) orforglipron ly3502970 foundayo (branded oral orforglipron \u2014 weight indication discussion) oral non-peptide glp-1 agonist oral small-molecule glp-1 ra lilly oral glp-1 (discussion shorthand) foundayo oral glp-1 food noise nausea any time rybelsus oral wegovy switch hair loss foundayo rybelsus oral wegovy pill fat loss appetite control glucose fat loss / obesity weight management appetite control / food-noise reduction glucose / glycemic discussion (t2d programs) weight management without injections metabolic / cardiometabolic health markers type 2 diabetes\u2013adjacent research and achieve program interest oral switch / maintenance after injectable incretins (attain-maintain) needle-averse glp-1 access interest primary-care scalable oral glp-1 talk foundayo oral glp-1 food noise nausea any time rybelsus oral wegovy switch hair loss pill orforglipron is a non-peptide glp-1 pill used for weight management; people look it up for reduced appetite without injections. orforglipron is a daily oral non-peptide glp-1 medicine discussed for weight management without injections. some report quieter food thoughts and earlier meal stopping; others notice little benefit or disruptive stomach symptoms. stomach symptoms can worsen after an increase. users weigh the convenience of a tablet against differing weight outcomes and their experiences with injectable medicines; a convenient switch does not guarantee the same result. metabolic / glp-1 class non-peptide systemic systemic oral glp-1 small molecule, not a peptide; appetite, satiety, gastric-emptying and glucose effects extend beyond the gut. systemic whole-body circulating", "legal_class": null }, { "id": 71, "slug": "pemvidutide", "name": "Pemvidutide", "aliases": [ "ALT-801", "GLP-1/glucagon dual agonist discussion", "Pemvidutide (Altimmune)", "GLP-1/glucagon dual agonist", "GLP-1R/GCGR dual agonist", "Balanced 1:1 GLP-1/glucagon coagonist", "EuPort GLP-1/glucagon dual agonist" ], "type": "Peptide", "category": "Metabolic / GLP-1 class", "goals_use_cases": [ "fat loss", "liver fat discussion", "metabolic health", "fat loss / obesity research", "liver fat / MASLD reduction", "MASH resolution discussion (biopsy-driven IMPACT data)", "body composition / lean-mass preservation talk", "appetite control (GLP-1 arm)", "energy-expenditure / fat-oxidation talk (glucagon arm)", "lipid and blood-pressure markers", "metabolic health without strong diabetes-drug framing", "alcohol use disorder (RECLAIM Phase 2 discussion)", "alcohol-associated liver disease pipeline talk (RESTORE program)" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "pemvidutide", "ALT-801", "Pemvidutide (Altimmune)", "GLP-1/glucagon dual agonist", "GLP-1R/GCGR dual agonist", "Balanced 1:1 GLP-1/glucagon coagonist", "fat loss / obesity research", "liver fat / masld reduction", "mash resolution discussion (biopsy-driven impact data)", "body composition / lean-mass preservation talk", "appetite control (glp-1 arm)", "energy-expenditure / fat-oxidation talk (glucagon arm)" ], "feel_search": [ "fat loss / obesity research", "liver fat / masld reduction", "mash resolution discussion (biopsy-driven impact data)", "body composition / lean-mass preservation talk", "appetite control (glp-1 arm)", "energy-expenditure / fat-oxidation talk (glucagon arm)" ], "summary": "Pemvidutide (ALT-801) is an investigational peptide that activates GLP-1 and glucagon receptors, studied for obesity and liver disease.", "search_blob": "pemvidutide pemvidutide alt-801 glp-1/glucagon dual agonist discussion pemvidutide (altimmune) glp-1/glucagon dual agonist glp-1r/gcgr dual agonist balanced 1:1 glp-1/glucagon coagonist euport glp-1/glucagon dual agonist pemvidutide alt-801 pemvidutide (altimmune) glp-1/glucagon dual agonist glp-1r/gcgr dual agonist balanced 1:1 glp-1/glucagon coagonist fat loss / obesity research liver fat / masld reduction mash resolution discussion (biopsy-driven impact data) body composition / lean-mass preservation talk appetite control (glp-1 arm) energy-expenditure / fat-oxidation talk (glucagon arm) fat loss liver fat discussion metabolic health fat loss / obesity research liver fat / masld reduction mash resolution discussion (biopsy-driven impact data) body composition / lean-mass preservation talk appetite control (glp-1 arm) energy-expenditure / fat-oxidation talk (glucagon arm) lipid and blood-pressure markers metabolic health without strong diabetes-drug framing alcohol use disorder (reclaim phase 2 discussion) alcohol-associated liver disease pipeline talk (restore program) fat loss / obesity research liver fat / masld reduction mash resolution discussion (biopsy-driven impact data) body composition / lean-mass preservation talk appetite control (glp-1 arm) energy-expenditure / fat-oxidation talk (glucagon arm) pemvidutide (alt-801) is an investigational peptide that activates glp-1 and glucagon receptors, studied for obesity and liver disease. the inspected liver-health thread discusses trial hopes; its personal success story is about tirzepatide, not pemvidutide. pemvidutide is an investigational glp-1/glucagon peptide discussed for weight loss and liver disease. the reviewed community material mainly discusses trial findings and hopes; its personal treatment stories concern other drugs. metabolic / glp-1 class peptide systemic systemic once-weekly dual glp-1/glucagon agonist \u2014 whole-body appetite, weight, cardiometabolic, and liver-fat effects rather than a local tissue inject. systemic whole-body circulating", "legal_class": null }, { "id": 72, "slug": "amycretin", "name": "Amycretin", "aliases": [ "Novo amycretin", "oral/sc amylin+GLP-1 discussion", "Zenagamtide (INN / public naming; same molecule)", "NNC0487-0111", "NN9487 / NN 9487 (development code)", "Unimolecular amylin + GLP-1 dual agonist", "GLP-1 / amylin / calcitonin receptor agonist (trial framing)", "Oral amycretin (SNAC tablet discussion)", "Subcutaneous amycretin (once-weekly)" ], "type": "Peptide", "category": "Metabolic / GLP-1 class", "goals_use_cases": [ "fat loss", "appetite control", "fat loss / chronic weight management", "appetite control and meal-size reduction", "satiety / dual-pathway food-noise cut", "metabolic health / cardiometabolic interest", "type 2 diabetes weight + glycemic co-interest", "glucose / HbA1c discussion (T2D programs)", "oral GLP-1-class interest (daily tablet path)", "once-weekly injectable dual-agonist interest", "body recomposition interest (confounded; lean mass still at risk with large deficits)", "post-mono-GLP-1 / pipeline comparison talk (vs CagriSema, tirz, reta)" ], "delivery_methods": [ "oral", "subcutaneous" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "amycretin", "Zenagamtide (INN / public naming; same molecule)", "NNC0487-0111", "NN9487 / NN 9487 (development code)", "Novo amycretin", "Unimolecular amylin + GLP-1 dual agonist", "fat loss / chronic weight management", "appetite control and meal-size reduction", "satiety / dual-pathway food-noise cut", "metabolic health / cardiometabolic interest", "type 2 diabetes weight + glycemic co-interest", "glucose / hba1c discussion (t2d programs)" ], "feel_search": [ "fat loss / chronic weight management", "appetite control and meal-size reduction", "satiety / dual-pathway food-noise cut", "metabolic health / cardiometabolic interest", "type 2 diabetes weight + glycemic co-interest", "glucose / hba1c discussion (t2d programs)" ], "summary": "Amycretin is an investigational peptide that activates both GLP-1 and amylin receptors, being studied as an injection and oral weight-management drug.", "search_blob": "amycretin amycretin novo amycretin oral/sc amylin+glp-1 discussion zenagamtide (inn / public naming; same molecule) nnc0487-0111 nn9487 / nn 9487 (development code) unimolecular amylin + glp-1 dual agonist glp-1 / amylin / calcitonin receptor agonist (trial framing) oral amycretin (snac tablet discussion) subcutaneous amycretin (once-weekly) amycretin zenagamtide (inn / public naming; same molecule) nnc0487-0111 nn9487 / nn 9487 (development code) novo amycretin unimolecular amylin + glp-1 dual agonist fat loss / chronic weight management appetite control and meal-size reduction satiety / dual-pathway food-noise cut metabolic health / cardiometabolic interest type 2 diabetes weight + glycemic co-interest glucose / hba1c discussion (t2d programs) fat loss appetite control fat loss / chronic weight management appetite control and meal-size reduction satiety / dual-pathway food-noise cut metabolic health / cardiometabolic interest type 2 diabetes weight + glycemic co-interest glucose / hba1c discussion (t2d programs) oral glp-1-class interest (daily tablet path) once-weekly injectable dual-agonist interest body recomposition interest (confounded; lean mass still at risk with large deficits) post-mono-glp-1 / pipeline comparison talk (vs cagrisema, tirz, reta) fat loss / chronic weight management appetite control and meal-size reduction satiety / dual-pathway food-noise cut metabolic health / cardiometabolic interest type 2 diabetes weight + glycemic co-interest glucose / hba1c discussion (t2d programs) amycretin is an investigational peptide that activates both glp-1 and amylin receptors, being studied as an injection and oral weight-management drug. a self-described trial participant reports much quieter food noise and lower appetite over nine months, with persistent constipation. participation is unverified. amycretin is a peptide people look up for fat loss and appetite. one self-described trial participant reports quieter hunger alongside persistent constipation and a recurring disconnected feeling; another blinded account describes a slower, uncertain response. metabolic / glp-1 class peptide systemic systemic glp-1/amylin dual-agonist peptide for appetite and metabolic research; weekly subq and daily oral trial formulations. systemic whole-body circulating", "legal_class": null }, { "id": 73, "slug": "snap-8", "name": "SNAP-8", "aliases": [ "Acetyl Octapeptide-3", "SNAP8", "Snap-8", "SNAP-8\u2122 peptide solution C (Lipotec / Lubrizol trade form)", "SNAP-8 Amide (trade-form discussions)", "Acetyl Glutamyl Heptapeptide-1 / -3 (INCI/cross-name discussions \u2014 naming inconsistent across vendors)", "Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH\u2082" ], "type": "Peptide", "category": "Skin, hair & tissue remodeling", "goals_use_cases": [ "skin/hair", "anti-aging discussion", "expression lines / dynamic wrinkles", "forehead & crow's feet appearance", "glabellar / frown-line appearance", "cosmetic peptide routines", "non-injectable Botox-alternative talk", "fine-line smoothing narratives", "DIY multi-peptide serum building", "between-Botox maintenance talk", "minority gray-market meso / intradermal discussion" ], "delivery_methods": [ "topical" ], "discussion_popularity": "Medium", "reach": "Local", "misspellings_search_terms": [ "snap-8", "snap 8", "snap8", "Acetyl Octapeptide-3", "SNAP-8\u2122 peptide solution C (Lipotec / Lubrizol trade form)", "SNAP-8 Amide (trade-form discussions)", "skin/hair", "anti-aging discussion", "expression lines / dynamic wrinkles", "forehead & crow's feet appearance", "glabellar / frown-line appearance", "cosmetic peptide routines" ], "feel_search": [ "skin/hair", "anti-aging discussion", "expression lines / dynamic wrinkles", "forehead & crow's feet appearance", "glabellar / frown-line appearance", "cosmetic peptide routines" ], "summary": "SNAP-8 is acetyl octapeptide-3, an eight-amino-acid cosmetic peptide related to Argireline and marketed for expression lines.", "search_blob": "snap-8 snap-8 acetyl octapeptide-3 snap8 snap-8 snap-8\u2122 peptide solution c (lipotec / lubrizol trade form) snap-8 amide (trade-form discussions) acetyl glutamyl heptapeptide-1 / -3 (inci/cross-name discussions \u2014 naming inconsistent across vendors) ac-glu-glu-met-gln-arg-arg-ala-asp-nh\u2082 snap-8 snap 8 snap8 acetyl octapeptide-3 snap-8\u2122 peptide solution c (lipotec / lubrizol trade form) snap-8 amide (trade-form discussions) skin/hair anti-aging discussion expression lines / dynamic wrinkles forehead & crow's feet appearance glabellar / frown-line appearance cosmetic peptide routines skin/hair anti-aging discussion expression lines / dynamic wrinkles forehead & crow's feet appearance glabellar / frown-line appearance cosmetic peptide routines non-injectable botox-alternative talk fine-line smoothing narratives diy multi-peptide serum building between-botox maintenance talk minority gray-market meso / intradermal discussion skin/hair anti-aging discussion expression lines / dynamic wrinkles forehead & crow's feet appearance glabellar / frown-line appearance cosmetic peptide routines snap-8 is acetyl octapeptide-3, an eight-amino-acid cosmetic peptide related to argireline and marketed for expression lines. one user reported smoother forehead lines from a snap-8, matrixyl and argireline blend; another used a different peptide combination. snap-8 is a cosmetic peptide discussed for softening facial expression lines. topical users report smoother lines, uncertain changes or no visible benefit, usually with other ingredients in the same routine. skin, hair & tissue remodeling peptide local local \u2014 a face serum, not a whole-body shot. local site pin topical", "legal_class": null }, { "id": 74, "slug": "argireline", "name": "Argireline", "aliases": [ "Acetyl Hexapeptide-8", "Argireline peptide", "Acetyl Hexapeptide-8 Amide", "Acetyl Hexapeptide-3 (legacy INCI / older literature naming \u2014 often treated as the same hexapeptide franchise)", "AH-8", "AHP-3 / acetylhexapeptide-3 (paper shorthand)", "Argireline\u2122 (Lipotec / Lubrizol trade name)", "Argireline\u00ae Amplified (next-gen franchise peptide \u2014 different sequence evolution, not classic AH-8)", "Argireline\u00ae YOUth (oil-soluble / LipoClear delivery line extension)", "Ac-EEMQRR-NH2", "Ac-Glu-Glu-Met-Gln-Arg-Arg-NH2", "Argireline Solution 10% (mass-market finished-product shorthand, e.g. The Ordinary)", "CAS 616204-22-9 (commonly listed for acetyl hexapeptide-8)" ], "type": "Peptide", "category": "Skin, hair & tissue remodeling", "goals_use_cases": [ "skin/hair", "anti-aging discussion", "expression-line / dynamic wrinkle reduction talk", "periorbital wrinkles (crow\u2019s feet)", "forehead lines and glabellar \u201c11s\u201d", "smile / nasolabial dynamic-line softing (secondary talk)", "cosmetic peptide routines", "non-injectable \u201cBotox alternative\u201d / \u201cBotox in a bottle\u201d marketing talk", "fine-line appearance and makeup-crease softing", "needle-averse maintenance between neuromodulator appointments (discussed, confounded)", "adjunct after botulinum toxin to \u201cextend\u201d freeze (pilot/medical-adjunct talk)", "DIY multi-peptide serum building", "minority gray-market meso / intradermal facial injection discussion" ], "delivery_methods": [ "topical" ], "discussion_popularity": "Medium", "reach": "Local", "misspellings_search_terms": [ "argireline", "Acetyl Hexapeptide-8", "Acetyl Hexapeptide-8 Amide", "Acetyl Hexapeptide-3 (legacy INCI / older literature naming \u2014 often treated as the same hexapeptide franchise)", "AH-8", "AHP-3 / acetylhexapeptide-3 (paper shorthand)", "skin/hair", "anti-aging discussion", "expression-line / dynamic wrinkle reduction talk", "periorbital wrinkles (crow\u2019s feet)", "forehead lines and glabellar \u201c11s\u201d", "smile / nasolabial dynamic-line softing (secondary talk)" ], "feel_search": [ "skin/hair", "anti-aging discussion", "expression-line / dynamic wrinkle reduction talk", "periorbital wrinkles (crow\u2019s feet)", "forehead lines and glabellar \u201c11s\u201d", "smile / nasolabial dynamic-line softing (secondary talk)" ], "summary": "Argireline is acetyl hexapeptide-8, a topical cosmetic peptide used in products aimed at softening expression lines.", "search_blob": "argireline argireline acetyl hexapeptide-8 argireline peptide acetyl hexapeptide-8 amide acetyl hexapeptide-3 (legacy inci / older literature naming \u2014 often treated as the same hexapeptide franchise) ah-8 ahp-3 / acetylhexapeptide-3 (paper shorthand) argireline\u2122 (lipotec / lubrizol trade name) argireline\u00ae amplified (next-gen franchise peptide \u2014 different sequence evolution, not classic ah-8) argireline\u00ae youth (oil-soluble / lipoclear delivery line extension) ac-eemqrr-nh2 ac-glu-glu-met-gln-arg-arg-nh2 argireline solution 10% (mass-market finished-product shorthand, e.g. the ordinary) cas 616204-22-9 (commonly listed for acetyl hexapeptide-8) argireline acetyl hexapeptide-8 acetyl hexapeptide-8 amide acetyl hexapeptide-3 (legacy inci / older literature naming \u2014 often treated as the same hexapeptide franchise) ah-8 ahp-3 / acetylhexapeptide-3 (paper shorthand) skin/hair anti-aging discussion expression-line / dynamic wrinkle reduction talk periorbital wrinkles (crow\u2019s feet) forehead lines and glabellar \u201c11s\u201d smile / nasolabial dynamic-line softing (secondary talk) skin/hair anti-aging discussion expression-line / dynamic wrinkle reduction talk periorbital wrinkles (crow\u2019s feet) forehead lines and glabellar \u201c11s\u201d smile / nasolabial dynamic-line softing (secondary talk) cosmetic peptide routines non-injectable \u201cbotox alternative\u201d / \u201cbotox in a bottle\u201d marketing talk fine-line appearance and makeup-crease softing needle-averse maintenance between neuromodulator appointments (discussed, confounded) adjunct after botulinum toxin to \u201cextend\u201d freeze (pilot/medical-adjunct talk) diy multi-peptide serum building minority gray-market meso / intradermal facial injection discussion skin/hair anti-aging discussion expression-line / dynamic wrinkle reduction talk periorbital wrinkles (crow\u2019s feet) forehead lines and glabellar \u201c11s\u201d smile / nasolabial dynamic-line softing (secondary talk) argireline is acetyl hexapeptide-8, a topical cosmetic peptide used in products aimed at softening expression lines. some users describe temporary smoothing or tightness, often with matrixyl. they explicitly say the effect does not match botox. argireline is a cosmetic peptide discussed for expression lines. some report softer-looking lines or less makeup creasing; others see no difference or develop irritation. these accounts do not establish a botox-like effect. skin, hair & tissue remodeling peptide local local \u2014 a face serum, not a whole-body shot. local site pin topical", "legal_class": null }, { "id": 75, "slug": "matrixyl", "name": "Matrixyl (palmitoyl pentapeptide-4)", "aliases": [ "Palmitoyl pentapeptide-4", "Matrixyl 3000 adjacency", "Palmitoyl pentapeptide-3 (pre-2006 INCI)", "Pal-KTTKS", "Pal-Lys-Thr-Thr-Lys-Ser", "Matrixyl", "Matrixyl\u2122 (Sederma / Croda trade name \u2014 classic)", "Matrixyl 3000 (related brand line; different peptides)", "Matrixyl Synthe'6 / Synthe\u20196 (related brand line; palmitoyl tripeptide-38)", "Matrixyl Morphomics (related brand line; palmitoyl tripeptide-56 acetate)", "PPP-4", "Collagen pentapeptide (community shorthand)" ], "type": "Peptide", "category": "Skin, hair & tissue remodeling", "goals_use_cases": [ "skin/hair", "anti-aging discussion", "fine lines & wrinkles", "collagen / firmness talk", "texture & density narratives", "cosmetic matrix remodeling", "photoaging appearance", "periocular / crow's feet talk", "tech-neck / barcode lip-line cosmetic talk", "gentler alternative-to-retinoid narratives", "DIY serum booster culture" ], "delivery_methods": [ "topical" ], "discussion_popularity": "Medium", "reach": "Local", "misspellings_search_terms": [ "matrixyl", "Matrixyl (palmitoyl pentapeptide-4)", "matrixyl-(palmitoyl-pentapeptide-4)", "Palmitoyl pentapeptide-4", "Palmitoyl pentapeptide-3 (pre-2006 INCI)", "Pal-KTTKS", "skin/hair", "anti-aging discussion", "fine lines & wrinkles", "collagen / firmness talk", "texture & density narratives", "cosmetic matrix remodeling" ], "feel_search": [ "skin/hair", "anti-aging discussion", "fine lines & wrinkles", "collagen / firmness talk", "texture & density narratives", "cosmetic matrix remodeling" ], "summary": "Original Matrixyl is palmitoyl pentapeptide-4, a cosmetic peptide used for fine lines; Matrixyl-branded blends and finished serums can contain different ingredients.", "search_blob": "matrixyl (palmitoyl pentapeptide-4) matrixyl palmitoyl pentapeptide-4 matrixyl 3000 adjacency palmitoyl pentapeptide-3 (pre-2006 inci) pal-kttks pal-lys-thr-thr-lys-ser matrixyl matrixyl\u2122 (sederma / croda trade name \u2014 classic) matrixyl 3000 (related brand line; different peptides) matrixyl synthe'6 / synthe\u20196 (related brand line; palmitoyl tripeptide-38) matrixyl morphomics (related brand line; palmitoyl tripeptide-56 acetate) ppp-4 collagen pentapeptide (community shorthand) matrixyl matrixyl (palmitoyl pentapeptide-4) matrixyl-(palmitoyl-pentapeptide-4) palmitoyl pentapeptide-4 palmitoyl pentapeptide-3 (pre-2006 inci) pal-kttks skin/hair anti-aging discussion fine lines & wrinkles collagen / firmness talk texture & density narratives cosmetic matrix remodeling skin/hair anti-aging discussion fine lines & wrinkles collagen / firmness talk texture & density narratives cosmetic matrix remodeling photoaging appearance periocular / crow's feet talk tech-neck / barcode lip-line cosmetic talk gentler alternative-to-retinoid narratives diy serum booster culture skin/hair anti-aging discussion fine lines & wrinkles collagen / firmness talk texture & density narratives cosmetic matrix remodeling original matrixyl is palmitoyl pentapeptide-4, a cosmetic peptide used for fine lines; matrixyl-branded blends and finished serums can contain different ingredients. a finished serum may feel hydrating or irritating: the reviewed user developed flaky, painful dryness within days and stopped. that does not identify which ingredient caused the reaction. matrixyl (palmitoyl pentapeptide-4) is a cosmetic peptide discussed for fine lines. finished-product reports include subtle smoothing, no change, and painful dryness or stinging; they do not isolate the peptide's effect. skin, hair & tissue remodeling peptide local local \u2014 discussed in topical skin serums and creams. local site pin topical", "legal_class": null }, { "id": 76, "slug": "melanotan-i", "name": "Melanotan I", "aliases": [ "Afamelanotide", "Scenesse", "MT-1", "NDP-MSH", "MT1", "Melanotan-1", "Melanotan 1", "[Nle4,D-Phe7]-\u03b1-MSH", "CUV1647", "Melanotan-I" ], "type": "Peptide", "category": "Tanning & melanocortin", "goals_use_cases": [ "skin/hair", "photoprotection discussion", "tanning / pigmentation", "UV-assisted bronze with fewer central sides than MT-II", "aesthetic skin tone", "UV tolerance (clinical EPP context)", "vitiligo adjunct discussion (clinical implant + NB-UVB)", "fair-skin melanin-density research context" ], "delivery_methods": [ "implant (clinical)", "injection discussion" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "melanotan-i", "melanotan i", "melanotani", "Afamelanotide", "Scenesse", "MT-1", "skin/hair", "photoprotection discussion", "tanning / pigmentation", "uv-assisted bronze with fewer central sides than mt-ii", "aesthetic skin tone", "uv tolerance (clinical epp context)" ], "feel_search": [ "skin/hair", "photoprotection discussion", "tanning / pigmentation", "uv-assisted bronze with fewer central sides than mt-ii", "aesthetic skin tone", "uv tolerance (clinical epp context)" ], "summary": "Melanotan I (afamelanotide) is an alpha-MSH analog affecting pigmentation; the medical implant and gray-market tanning vials are different formulations.", "search_blob": "melanotan i melanotan-i afamelanotide scenesse mt-1 ndp-msh mt1 melanotan-1 melanotan 1 [nle4,d-phe7]-\u03b1-msh cuv1647 melanotan-i melanotan-i melanotan i melanotani afamelanotide scenesse mt-1 skin/hair photoprotection discussion tanning / pigmentation uv-assisted bronze with fewer central sides than mt-ii aesthetic skin tone uv tolerance (clinical epp context) skin/hair photoprotection discussion tanning / pigmentation uv-assisted bronze with fewer central sides than mt-ii aesthetic skin tone uv tolerance (clinical epp context) vitiligo adjunct discussion (clinical implant + nb-uvb) fair-skin melanin-density research context skin/hair photoprotection discussion tanning / pigmentation uv-assisted bronze with fewer central sides than mt-ii aesthetic skin tone uv tolerance (clinical epp context) melanotan i (afamelanotide) is an alpha-msh analog affecting pigmentation; the medical implant and gray-market tanning vials are different formulations. melanotan i, or afamelanotide, is a pigment-stimulating peptide. community vial reports range from darker skin with uv exposure to little change, with nausea, flushing or exhaustion in some accounts. the medical implant has a separate clinical use and exposure pattern. tanning & melanocortin peptide systemic systemic mc1r-preferring \u03b1-msh analog; the licensed product is an implant, while community reports describe unverified subq vials. systemic whole-body circulating", "legal_class": null }, { "id": 77, "slug": "tesofensine", "name": "Tesofensine", "aliases": [ "NS2330", "NS-2330", "NS 2330", "Tesofensine hydrochloride", "Tesofensine HCl", "Tesofensine citrate (research-salt discussions)", "phenyltropane triple reuptake inhibitor (class talk)" ], "type": "Non-peptide", "category": "Metabolic research compounds", "goals_use_cases": [ "fat loss", "appetite control", "appetite control / food-noise reduction", "weight management research", "metabolic research", "craving reduction (discussed)", "body composition / lean-preservation narratives", "oral non-GLP-1 fat-loss alternative (community)", "energy expenditure / resting EE talk (preclinical + early human)", "GLP-1 stack adjunct for residual hunger (community)", "focus / motivation side-effect framing (anecdote)", "hypothalamic obesity / Tesomet-adjacent discussion" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "tesofensine", "NS2330", "NS-2330", "NS 2330", "Tesofensine hydrochloride", "Tesofensine HCl", "dry mouth", "insomnia", "heart rate", "food noise", "morning", "0.5 mg", "BioFlow", "appetite", "focus" ], "feel_search": [ "dry mouth", "insomnia", "heart rate", "food noise", "morning", "0.5 mg", "BioFlow", "appetite", "focus" ], "summary": "Tesofensine is an oral monoamine reuptake inhibitor discussed for appetite. Some report quieter food cravings and dry mouth; others remain hungry or develop sleep, mood or pulse\u2026", "search_blob": "tesofensine tesofensine ns2330 ns-2330 ns 2330 tesofensine hydrochloride tesofensine hcl tesofensine citrate (research-salt discussions) phenyltropane triple reuptake inhibitor (class talk) tesofensine ns2330 ns-2330 ns 2330 tesofensine hydrochloride tesofensine hcl dry mouth insomnia heart rate food noise morning 0.5 mg bioflow appetite focus fat loss appetite control appetite control / food-noise reduction weight management research metabolic research craving reduction (discussed) body composition / lean-preservation narratives oral non-glp-1 fat-loss alternative (community) energy expenditure / resting ee talk (preclinical + early human) glp-1 stack adjunct for residual hunger (community) focus / motivation side-effect framing (anecdote) hypothalamic obesity / tesomet-adjacent discussion dry mouth insomnia heart rate food noise morning 0.5 mg bioflow appetite focus tesofensine is an oral monoamine reuptake inhibitor discussed for appetite. some report quieter food cravings and dry mouth; others remain hungry or develop sleep, mood or pulse\u2026 reports disagree on sleep: some describe prolonged wakefulness or repeated waking, while another says their sleep schedule improved. tesofensine is an oral monoamine reuptake inhibitor discussed for appetite. some report quieter food cravings and dry mouth; others remain hungry or develop sleep, mood or pulse problems. tracker changes differ across accounts. early-day use and 0.5 mg are frequently discussed, but morning timing does not prevent every sleep problem. heart-rate increases and long-lasting exposure remain concerns. metabolic research compounds non-peptide systemic systemic \u2014 an oral monoamine reuptake inhibitor discussed for appetite, food reward and energy balance; not a local or site-specific injection. systemic whole-body circulating", "legal_class": null }, { "id": 78, "slug": "bam15", "name": "BAM15", "aliases": [ "mitochondrial uncoupler BAM15", "BAM-15", "BAM 15", "mitochondrial protonophore BAM15", "oxadiazolo-pyrazine uncoupler BAM15", "N5,N6-bis(2-fluorophenyl)[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine", "N5,N6-bis(2-fluorophenyl)-[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine", "CAS 210302-17-3", "\u201csafer DNP\u201d BAM15 (community nickname)" ], "type": "Non-peptide", "category": "Metabolic research compounds", "goals_use_cases": [ "fat loss", "metabolic health", "fat loss / energy-expenditure uncoupling", "body recomposition with lean-mass sparing (preclinical narrative)", "metabolic health / insulin sensitivity research (preclinical)", "fatty liver / hepatic steatosis narratives (preclinical)", "glucose tolerance / diabetes-adjacent models (animal)", "DNP-alternative discussion (\u201csafer uncoupler\u201d lore)", "sarcopenic obesity / aged-muscle protection (preclinical)", "anti-inflammatory / antioxidant liver talk (preclinical metabolomics)", "atherosclerosis / AMPK\u2013NLRP3 research adjacency (preclinical)", "GLP-1 add-on when appetite drugs stall (community theory)", "mitochondrial uncoupling research tool" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "bam15", "BAM-15", "BAM 15", "mitochondrial uncoupler BAM15", "mitochondrial protonophore BAM15", "oxadiazolo-pyrazine uncoupler BAM15", "safer DNP", "uncoupler", "heat", "night sweats", "SLU", "250mg", "inject", "thermogenic", "mitochondria" ], "feel_search": [ "safer DNP", "uncoupler", "heat", "night sweats", "SLU", "250mg", "inject", "thermogenic", "mitochondria" ], "summary": "BAM15 is a mitochondrial uncoupler discussed for fat loss, not a peptide or approved weight-loss medicine. No solid human RCT or approved label for weight loss as of research cut.", "search_blob": "bam15 bam15 mitochondrial uncoupler bam15 bam-15 bam 15 mitochondrial protonophore bam15 oxadiazolo-pyrazine uncoupler bam15 n5,n6-bis(2-fluorophenyl)[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine n5,n6-bis(2-fluorophenyl)-[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine cas 210302-17-3 \u201csafer dnp\u201d bam15 (community nickname) bam15 bam-15 bam 15 mitochondrial uncoupler bam15 mitochondrial protonophore bam15 oxadiazolo-pyrazine uncoupler bam15 safer dnp uncoupler heat night sweats slu 250mg inject thermogenic mitochondria fat loss metabolic health fat loss / energy-expenditure uncoupling body recomposition with lean-mass sparing (preclinical narrative) metabolic health / insulin sensitivity research (preclinical) fatty liver / hepatic steatosis narratives (preclinical) glucose tolerance / diabetes-adjacent models (animal) dnp-alternative discussion (\u201csafer uncoupler\u201d lore) sarcopenic obesity / aged-muscle protection (preclinical) anti-inflammatory / antioxidant liver talk (preclinical metabolomics) atherosclerosis / ampk\u2013nlrp3 research adjacency (preclinical) glp-1 add-on when appetite drugs stall (community theory) mitochondrial uncoupling research tool safer dnp uncoupler heat night sweats slu 250mg inject thermogenic mitochondria bam15 is a mitochondrial uncoupler discussed for fat loss, not a peptide or approved weight-loss medicine. no solid human rct or approved label for weight loss as of research cut. a combined bam15/sana log describes little at first, warmth near week one and later weight loss. hot weather and the second compound limit attribution. bam15 is a mitochondrial uncoupler discussed for fat loss, not a peptide or approved weight-loss medicine. no solid human rct or approved label for weight loss as of research cut. 2026 amount claims range from a few mg to 250 mg capsules and grams per day. warmth does not establish effectiveness or safe exposure. metabolic research compounds non-peptide systemic systemic \u2014 an oral mitochondrial uncoupler in fat-loss discussion; mouse liver/adipose findings do not prove human safety or spot-fat effects. systemic whole-body circulating", "legal_class": null }, { "id": 79, "slug": "urolithin-a", "name": "Urolithin A", "aliases": [ "Mitopure-class discussion", "UA", "Uro-A", "UroA", "Mitopure", "Mitopure-class UA", "Timeline Mitopure", "3,8-Dihydroxy-urolithin", "3,8-dihydroxy-6H-dibenzo[b,d]pyran-6-one", "ellagitannin gut metabolite", "pomegranate postbiotic UA" ], "type": "Non-peptide", "category": "Longevity & cellular energy", "goals_use_cases": [ "longevity", "muscle", "mitochondrial discussion", "longevity / healthy aging", "mitophagy / mitochondrial recycling", "muscle strength (middle-age RCT talk)", "muscle endurance / fatigue resistance (older-adult RCT talk)", "endurance / aerobic capacity markers (VO2, 6-min walk)", "cellular energy without stimulant feel", "training recovery continuity", "inflammation biomarker discussion (CRP / cytokines)", "non-producer food-bypass strategy", "joint / osteoarthritis interest (mostly preclinical)", "topical skin aging (separate cream trials)", "immune-aging / immunosenescence research interest", "sports-nutrition adjunct discussion (emerging)", "stack companion to NAD precursors and autophagy agents" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "urolithin-a", "urolithin a", "urolithina", "UA", "Uro-A", "UroA", "energy", "recovery", "HRV", "mitopure", "fake", "heavy legs" ], "feel_search": [ "energy", "recovery", "HRV", "mitopure", "fake", "heavy legs" ], "summary": "Urolithin A is a gut-microbe-derived metabolite of compounds in foods such as pomegranate and walnuts, also sold as an oral supplement.", "search_blob": "urolithin a urolithin-a mitopure-class discussion ua uro-a uroa mitopure mitopure-class ua timeline mitopure 3,8-dihydroxy-urolithin 3,8-dihydroxy-6h-dibenzo[b,d]pyran-6-one ellagitannin gut metabolite pomegranate postbiotic ua urolithin-a urolithin a urolithina ua uro-a uroa energy recovery hrv mitopure fake heavy legs longevity muscle mitochondrial discussion longevity / healthy aging mitophagy / mitochondrial recycling muscle strength (middle-age rct talk) muscle endurance / fatigue resistance (older-adult rct talk) endurance / aerobic capacity markers (vo2, 6-min walk) cellular energy without stimulant feel training recovery continuity inflammation biomarker discussion (crp / cytokines) non-producer food-bypass strategy joint / osteoarthritis interest (mostly preclinical) topical skin aging (separate cream trials) immune-aging / immunosenescence research interest sports-nutrition adjunct discussion (emerging) stack companion to nad precursors and autophagy agents energy recovery hrv mitopure fake heavy legs urolithin a is a gut-microbe-derived metabolite of compounds in foods such as pomegranate and walnuts, also sold as an oral supplement. some users describe greater workout capacity or clearer energy; others report marked fatigue, and daily-life benefits are inconsistent. urolithin a is a food-derived metabolite also sold as an oral supplement. reports range from greater workout capacity or steadier energy to no change, fatigue or disrupted sleep; a felt response does not demonstrate mitochondrial cleanup. 500 mg and 1,000 mg appear in trial arms and community charts with different endpoints. saved 2025\u201326 discussions also question product content and label changes; a listed amount does not verify the contents. longevity & cellular energy non-peptide systemic systemic oral postbiotic for whole-body mitophagy and muscle/mitochondrial endpoints \u2014 not a local inject and not a classical stimulant. systemic whole-body circulating", "legal_class": null }, { "id": 80, "slug": "spermidine", "name": "Spermidine", "aliases": [ "dietary spermidine", "polyamine longevity discussion", "spermidine trihydrochloride", "spermidine 3HCl / 3HCL", "hpSPD (high-purity spermidine)", "wheat-germ spermidine extract", "CelVio\u00ae / spermidineLIFE-type extract", "N-(3-aminopropyl)butane-1,4-diamine", "polyamine (putrescine \u2192 spermidine \u2192 spermine axis)" ], "type": "Non-peptide", "category": "Longevity & cellular energy", "goals_use_cases": [ "longevity", "autophagy discussion", "longevity / healthy aging", "autophagy / cellular cleanup narratives", "caloric-restriction / fasting mimetic talk", "cognition / memory in older adults (mixed trials)", "cardiometabolic / cardiac remodeling interest (preclinical + POLYCAD)", "immune aging / T-cell autophagy discussion", "hair anagen / follicle talk (sparse human supplement data)", "skin / \u201ccellular renewal\u201d marketing", "food-first polyamine intake optimization", "stack companion to NMN/NR, resveratrol, rapamycin, fisetin" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "spermidine", "dietary spermidine", "polyamine longevity discussion", "spermidine trihydrochloride", "spermidine 3HCl / 3HCL", "hpSPD (high-purity spermidine)", "longevity / healthy aging", "autophagy / cellular cleanup narratives", "caloric-restriction / fasting mimetic talk", "cognition / memory in older adults (mixed trials)", "cardiometabolic / cardiac remodeling interest (preclinical + polycad)", "immune aging / t-cell autophagy discussion" ], "feel_search": [ "longevity / healthy aging", "autophagy / cellular cleanup narratives", "caloric-restriction / fasting mimetic talk", "cognition / memory in older adults (mixed trials)", "cardiometabolic / cardiac remodeling interest (preclinical + polycad)", "immune aging / t-cell autophagy discussion" ], "summary": "Spermidine is a naturally occurring polyamine found in foods and sold as extracts or purified salts for longevity-related interests.", "search_blob": "spermidine spermidine dietary spermidine polyamine longevity discussion spermidine trihydrochloride spermidine 3hcl / 3hcl hpspd (high-purity spermidine) wheat-germ spermidine extract celvio\u00ae / spermidinelife-type extract n-(3-aminopropyl)butane-1,4-diamine polyamine (putrescine \u2192 spermidine \u2192 spermine axis) spermidine dietary spermidine polyamine longevity discussion spermidine trihydrochloride spermidine 3hcl / 3hcl hpspd (high-purity spermidine) longevity / healthy aging autophagy / cellular cleanup narratives caloric-restriction / fasting mimetic talk cognition / memory in older adults (mixed trials) cardiometabolic / cardiac remodeling interest (preclinical + polycad) immune aging / t-cell autophagy discussion longevity autophagy discussion longevity / healthy aging autophagy / cellular cleanup narratives caloric-restriction / fasting mimetic talk cognition / memory in older adults (mixed trials) cardiometabolic / cardiac remodeling interest (preclinical + polycad) immune aging / t-cell autophagy discussion hair anagen / follicle talk (sparse human supplement data) skin / \u201ccellular renewal\u201d marketing food-first polyamine intake optimization stack companion to nmn/nr, resveratrol, rapamycin, fisetin longevity / healthy aging autophagy / cellular cleanup narratives caloric-restriction / fasting mimetic talk cognition / memory in older adults (mixed trials) cardiometabolic / cardiac remodeling interest (preclinical + polycad) immune aging / t-cell autophagy discussion spermidine is a naturally occurring polyamine found in foods and sold as extracts or purified salts for longevity-related interests. one user noticed no benefit, while another described body heat and disturbed sleep with a different brand. spermidine is a naturally occurring polyamine discussed for longevity. users report no change, sleep or hair improvements, and unwanted effects. a small positive memory pilot was followed by a larger 12-month trial with no significant memory benefit. longevity & cellular energy non-peptide systemic systemic oral polyamine already present in tissues and diet; marketed as body-wide autophagy/aging support, not a single-organ drug or injectable peptide. systemic whole-body circulating", "legal_class": null }, { "id": 81, "slug": "fisetin", "name": "Fisetin", "aliases": [ "3,3',4',7-tetrahydroxyflavone", "3,3\u2032,4\u2032,7-Tetrahydroxyflavone", "Fisetin flavonoid", "Natural fisetin", "Senolytic fisetin (discussion label)", "Novusetin (branded ~95% fisetin extract, often Rhus-derived)", "Cognisetin (marketing / memory-branded fisetin label)", "FF-20 / hybrid-hydrogel fisetin (enhanced-bioavailability research form)" ], "type": "Non-peptide", "category": "Senolytic & longevity compounds", "goals_use_cases": [ "longevity", "senolytic discussion", "longevity / healthspan", "senolytic / zombie-cell clearance discussion", "healthy aging / frailty and physical function interest", "inflammation / SASP-burden narratives", "cellular senescence markers (research endpoints)", "cognitive aging / neuroprotection interest (mostly preclinical + minority user logs)", "antioxidant / polyphenol stack interest", "metabolic aging and diabetes-adjacent inflammation talk (preclinical + trial interest)", "allergy / mast-cell / nasal inflammation crossover (anecdotal + older mouse work)", "vs D+Q natural single-agent alternative" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "fisetin", "3,3',4',7-tetrahydroxyflavone", "3,3\u2032,4\u2032,7-Tetrahydroxyflavone", "Fisetin flavonoid", "Natural fisetin", "Senolytic fisetin (discussion label)", "longevity / healthspan", "senolytic / zombie-cell clearance discussion", "healthy aging / frailty and physical function interest", "inflammation / sasp-burden narratives", "cellular senescence markers (research endpoints)", "cognitive aging / neuroprotection interest (mostly preclinical + minority user logs)" ], "feel_search": [ "longevity / healthspan", "senolytic / zombie-cell clearance discussion", "healthy aging / frailty and physical function interest", "inflammation / sasp-burden narratives", "cellular senescence markers (research endpoints)", "cognitive aging / neuroprotection interest (mostly preclinical + minority user logs)" ], "summary": "Fisetin is a plant flavonol sold as a supplement and studied experimentally for effects on senescent cells and aging biology.", "search_blob": "fisetin fisetin 3,3',4',7-tetrahydroxyflavone 3,3\u2032,4\u2032,7-tetrahydroxyflavone fisetin flavonoid natural fisetin senolytic fisetin (discussion label) novusetin (branded ~95% fisetin extract, often rhus-derived) cognisetin (marketing / memory-branded fisetin label) ff-20 / hybrid-hydrogel fisetin (enhanced-bioavailability research form) fisetin 3,3',4',7-tetrahydroxyflavone 3,3\u2032,4\u2032,7-tetrahydroxyflavone fisetin flavonoid natural fisetin senolytic fisetin (discussion label) longevity / healthspan senolytic / zombie-cell clearance discussion healthy aging / frailty and physical function interest inflammation / sasp-burden narratives cellular senescence markers (research endpoints) cognitive aging / neuroprotection interest (mostly preclinical + minority user logs) longevity senolytic discussion longevity / healthspan senolytic / zombie-cell clearance discussion healthy aging / frailty and physical function interest inflammation / sasp-burden narratives cellular senescence markers (research endpoints) cognitive aging / neuroprotection interest (mostly preclinical + minority user logs) antioxidant / polyphenol stack interest metabolic aging and diabetes-adjacent inflammation talk (preclinical + trial interest) allergy / mast-cell / nasal inflammation crossover (anecdotal + older mouse work) vs d+q natural single-agent alternative longevity / healthspan senolytic / zombie-cell clearance discussion healthy aging / frailty and physical function interest inflammation / sasp-burden narratives cellular senescence markers (research endpoints) cognitive aging / neuroprotection interest (mostly preclinical + minority user logs) fisetin is a plant flavonol sold as a supplement and studied experimentally for effects on senescent cells and aging biology. one multi-ingredient senolytic account describes profound fatigue within eight hours lasting days, while acknowledging possible illness. that is not proof of cell clearance. fisetin is a plant flavonol discussed for aging cells. reports include joint or sinus comfort, easier word-finding, no change, and unwanted fatigue, weakness or brain fog; none of these sensations proves cell clearance. senolytic & longevity compounds non-peptide systemic systemic oral flavonoid for whole-body senescent-cell, sasp, and aging-inflammation talk\u2014not a local injury inject, peptide, or tissue-targeted therapy. systemic whole-body circulating", "legal_class": null }, { "id": 82, "slug": "quercetin", "name": "Quercetin", "aliases": [ "quercetin phytosome discussion", "Quercetin dihydrate", "Quercetin aglycone", "Quercetin phytosome", "Quercetin Phytosome\u2122", "Quercefit", "QuerceFit\u00ae", "EMIQ", "Enzymatically modified isoquercitrin", "Isoquercetin", "3,3\u2032,4\u2032,5,7-pentahydroxyflavone", "SOPHORIN (historical plant-flavonoid context)", "D+Q (with dasatinib)" ], "type": "Non-peptide", "category": "Senolytic & longevity compounds", "goals_use_cases": [ "longevity", "immune", "senolytic stack discussion", "inflammation (discussed)", "allergy / seasonal comfort (discussed)", "mast-cell / histamine talk", "antioxidant support (discussed)", "metabolic markers (discussed)", "uric acid / gout-adjacent discussion", "recovery continuity", "upper-respiratory season stacks (community)", "zinc ionophore narrative (community)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "quercetin", "Quercetin dihydrate", "Quercetin aglycone", "Quercetin phytosome", "Quercetin Phytosome\u2122", "Quercefit", "longevity", "immune", "senolytic stack discussion", "inflammation (discussed)", "allergy / seasonal comfort (discussed)", "mast-cell / histamine talk" ], "feel_search": [ "longevity", "immune", "senolytic stack discussion", "inflammation (discussed)", "allergy / seasonal comfort (discussed)", "mast-cell / histamine talk" ], "summary": "Quercetin is a plant flavonol sold as an oral supplement and discussed for allergy, mast-cell and longevity-related interests.", "search_blob": "quercetin quercetin quercetin phytosome discussion quercetin dihydrate quercetin aglycone quercetin phytosome quercetin phytosome\u2122 quercefit quercefit\u00ae emiq enzymatically modified isoquercitrin isoquercetin 3,3\u2032,4\u2032,5,7-pentahydroxyflavone sophorin (historical plant-flavonoid context) d+q (with dasatinib) quercetin quercetin dihydrate quercetin aglycone quercetin phytosome quercetin phytosome\u2122 quercefit longevity immune senolytic stack discussion inflammation (discussed) allergy / seasonal comfort (discussed) mast-cell / histamine talk longevity immune senolytic stack discussion inflammation (discussed) allergy / seasonal comfort (discussed) mast-cell / histamine talk antioxidant support (discussed) metabolic markers (discussed) uric acid / gout-adjacent discussion recovery continuity upper-respiratory season stacks (community) zinc ionophore narrative (community) longevity immune senolytic stack discussion inflammation (discussed) allergy / seasonal comfort (discussed) mast-cell / histamine talk quercetin is a plant flavonol sold as an oral supplement and discussed for allergy, mast-cell and longevity-related interests. some posters describe feeling better, while others report headaches, gi upset or worse symptoms; the responses are sharply mixed. quercetin is a plant flavonol sold as an oral supplement. allergy and histamine discussions include relief, no benefit and worse symptoms; intermittent use with prescription dasatinib is a separate longevity-research topic. senolytic & longevity compounds non-peptide systemic systemic oral flavonol used in supplement and d+q discussions; food, aglycone, glycoside and enhanced-absorption forms are not equivalent. systemic whole-body circulating", "legal_class": null }, { "id": 83, "slug": "dasatinib", "name": "Dasatinib", "aliases": [ "Sprycel", "D+Q senolytic pair discussion", "BMS-354825", "Phyrago (dasatinib tablets brand discussed in PK notes)", "D+Q (with quercetin)", "DQ / D&Q senolytic pair", "Dasatinib + quercetin senolytic pair", "Intermittent dasatinib (senolytic pulse talk)" ], "type": "Non-peptide", "category": "Senolytic & longevity compounds", "goals_use_cases": [ "longevity", "senolytic discussion", "longevity / geroscience discussion", "senolytic / senescent-cell clearance discussion", "cellular senescence and SASP burden (research)", "frailty / physical function (discussed in IPF and aging pilots)", "age-related tissue burden (adipose, bone, disc \u2014 research)", "IPF / fibrotic disease research contexts", "diabetic kidney disease / CKD aging pilots", "postmenopausal bone metabolism (phase 2)", "cognitive aging / MCI\u2013AD early trials (SToMP-AD family)", "metabolic / obesity / fatty-liver aging interest (preclinical + listed trials)", "stem-cell transplant / premature-aging survivor research interest", "not primary: continuous CML/Ph+ ALL oncology use (labeled indication; different regimen)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "dasatinib", "Sprycel", "BMS-354825", "Phyrago (dasatinib tablets brand discussed in PK notes)", "D+Q (with quercetin)", "DQ / D&Q senolytic pair", "longevity / geroscience discussion", "senolytic / senescent-cell clearance discussion", "cellular senescence and sasp burden (research)", "frailty / physical function (discussed in ipf and aging pilots)", "age-related tissue burden (adipose, bone, disc \u2014 research)", "ipf / fibrotic disease research contexts" ], "feel_search": [ "longevity / geroscience discussion", "senolytic / senescent-cell clearance discussion", "cellular senescence and sasp burden (research)", "frailty / physical function (discussed in ipf and aging pilots)", "age-related tissue burden (adipose, bone, disc \u2014 research)", "ipf / fibrotic disease research contexts" ], "summary": "Dasatinib (Sprycel) is a prescription tyrosine-kinase inhibitor for certain leukemias, also studied with quercetin in experimental senolytic research.", "search_blob": "dasatinib dasatinib sprycel d+q senolytic pair discussion bms-354825 phyrago (dasatinib tablets brand discussed in pk notes) d+q (with quercetin) dq / d&q senolytic pair dasatinib + quercetin senolytic pair intermittent dasatinib (senolytic pulse talk) dasatinib sprycel bms-354825 phyrago (dasatinib tablets brand discussed in pk notes) d+q (with quercetin) dq / d&q senolytic pair longevity / geroscience discussion senolytic / senescent-cell clearance discussion cellular senescence and sasp burden (research) frailty / physical function (discussed in ipf and aging pilots) age-related tissue burden (adipose, bone, disc \u2014 research) ipf / fibrotic disease research contexts longevity senolytic discussion longevity / geroscience discussion senolytic / senescent-cell clearance discussion cellular senescence and sasp burden (research) frailty / physical function (discussed in ipf and aging pilots) age-related tissue burden (adipose, bone, disc \u2014 research) ipf / fibrotic disease research contexts diabetic kidney disease / ckd aging pilots postmenopausal bone metabolism (phase 2) cognitive aging / mci\u2013ad early trials (stomp-ad family) metabolic / obesity / fatty-liver aging interest (preclinical + listed trials) stem-cell transplant / premature-aging survivor research interest not primary: continuous cml/ph+ all oncology use (labeled indication; different regimen) longevity / geroscience discussion senolytic / senescent-cell clearance discussion cellular senescence and sasp burden (research) frailty / physical function (discussed in ipf and aging pilots) age-related tissue burden (adipose, bone, disc \u2014 research) ipf / fibrotic disease research contexts dasatinib (sprycel) is a prescription tyrosine-kinase inhibitor for certain leukemias, also studied with quercetin in experimental senolytic research. d+q users report both no noticeable change and improvements while also using rapamycin and other agents. those accounts cannot isolate dasatinib or prove senescent-cell clearance. dasatinib is a prescription oral leukemia drug also studied with quercetin in experimental senolytic research. reports include improvement, no noticeable benefit and difficult side effects; healthy-adult healthspan or lifespan benefit remains unproven. senolytic & longevity compounds non-peptide systemic systemic oral multi-kinase (bcr-abl / src-family) small molecule. systemic whole-body circulating", "legal_class": null }, { "id": 84, "slug": "ca-akg", "name": "Ca-AKG", "aliases": [ "Calcium alpha-ketoglutarate", "AKG", "Calcium \u03b1-ketoglutarate", "CaAKG", "Ca AKG", "Calcium aKG", "AKG (calcium salt form)", "dAKG (delayed-release CaAKG, product framing)", "LifeAKG\u2122 (Rejuvant / timed-release ingredient branding)", "Calcium alpha-ketoglutarate monohydrate", "AKG-Ca / Ca-aKG (literature variants)" ], "type": "Non-peptide", "category": "Longevity & cellular energy", "goals_use_cases": [ "longevity", "metabolic health", "longevity / healthspan", "biological age / DNA-methylation clock interest", "metabolic health / TCA-cycle support (discussed)", "cellular energy narratives", "inflammation / inflammaging talk (animal-driven)", "frailty compression narratives (mouse)", "bone / osteopenia context (older high-dose human work)", "muscle / sarcopenia interest (secondary endpoints, animal atrophy models)", "hemodialysis / nitrogen-balance historical clinical use", "multi-ingredient longevity formulas (e.g., NOVOS-style, Rejuvant-style)", "stack companion to NMN/NR and other aging compounds", "vs AAKG sport products \u2014 longevity users prefer calcium salt" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "ca-akg", "ca akg", "caakg", "Calcium alpha-ketoglutarate", "Calcium \u03b1-ketoglutarate", "Calcium aKG", "longevity / healthspan", "biological age / dna-methylation clock interest", "metabolic health / tca-cycle support (discussed)", "cellular energy narratives", "inflammation / inflammaging talk (animal-driven)", "frailty compression narratives (mouse)" ], "feel_search": [ "longevity / healthspan", "biological age / dna-methylation clock interest", "metabolic health / tca-cycle support (discussed)", "cellular energy narratives", "inflammation / inflammaging talk (animal-driven)", "frailty compression narratives (mouse)" ], "summary": "Calcium alpha-ketoglutarate (Ca-AKG) is a calcium salt of an energy-metabolism compound, sold for longevity and exercise interest.", "search_blob": "ca-akg ca-akg calcium alpha-ketoglutarate akg calcium \u03b1-ketoglutarate caakg ca akg calcium akg akg (calcium salt form) dakg (delayed-release caakg, product framing) lifeakg\u2122 (rejuvant / timed-release ingredient branding) calcium alpha-ketoglutarate monohydrate akg-ca / ca-akg (literature variants) ca-akg ca akg caakg calcium alpha-ketoglutarate calcium \u03b1-ketoglutarate calcium akg longevity / healthspan biological age / dna-methylation clock interest metabolic health / tca-cycle support (discussed) cellular energy narratives inflammation / inflammaging talk (animal-driven) frailty compression narratives (mouse) longevity metabolic health longevity / healthspan biological age / dna-methylation clock interest metabolic health / tca-cycle support (discussed) cellular energy narratives inflammation / inflammaging talk (animal-driven) frailty compression narratives (mouse) bone / osteopenia context (older high-dose human work) muscle / sarcopenia interest (secondary endpoints, animal atrophy models) hemodialysis / nitrogen-balance historical clinical use multi-ingredient longevity formulas (e.g., novos-style, rejuvant-style) stack companion to nmn/nr and other aging compounds vs aakg sport products \u2014 longevity users prefer calcium salt longevity / healthspan biological age / dna-methylation clock interest metabolic health / tca-cycle support (discussed) cellular energy narratives inflammation / inflammaging talk (animal-driven) frailty compression narratives (mouse) calcium alpha-ketoglutarate (ca-akg) is a calcium salt of an energy-metabolism compound, sold for longevity and exercise interest. a ca-akg user describes subtle running benefits across continued use, while other akg users report none. reports using other salts are not calcium-form evidence. calcium alpha-ketoglutarate is an oral compound discussed for longevity. reports include subtle energy or recovery changes, no benefit, stomach pain, anxiety and brain fog; products and concurrent supplements vary. longevity & cellular energy non-peptide systemic systemic \u2014 oral ca-akg is discussed for whole-body metabolic, inflammatory, epigenetic-clock, and longevity support, not local tissue targeting. systemic whole-body circulating", "legal_class": null }, { "id": 85, "slug": "glutathione", "name": "Glutathione", "aliases": [ "GSH", "L-glutathione", "liposomal glutathione", "reduced glutathione", "S-acetyl glutathione (SAG)", "\u03b3-L-glutamyl-L-cysteinylglycine", "Setria glutathione (branded oral form discussions)", "oxidized glutathione (GSSG)" ], "type": "Peptide", "category": "Antioxidant & detox discussion", "goals_use_cases": [ "skin/hair", "detox discussion", "immune", "recovery", "skin lightening / melasma / pigmentation (discussed)", "detox / liver support discussion", "immune / NK-cell adjacency", "oxidative stress / redox balance", "recovery / athletic \u201cglow\u201d talk", "longevity / master-antioxidant narratives", "Parkinson\u2019s IV and intranasal research adjacency", "fatty-liver / metabolic discussion", "IV med-spa wellness menus" ], "delivery_methods": [ "IV", "oral", "nebulized (discussed)", "sublingual" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "glutathione", "GSH", "L-glutathione", "reduced glutathione", "liposomal glutathione", "S-acetyl glutathione (SAG)", "skin lightening / melasma / pigmentation (discussed)", "detox / liver support discussion", "immune / nk-cell adjacency", "oxidative stress / redox balance", "recovery / athletic \u201cglow\u201d talk", "longevity / master-antioxidant narratives" ], "feel_search": [ "skin lightening / melasma / pigmentation (discussed)", "detox / liver support discussion", "immune / nk-cell adjacency", "oxidative stress / redox balance", "recovery / athletic \u201cglow\u201d talk", "longevity / master-antioxidant narratives" ], "summary": "Glutathione is a small antioxidant peptide; people discuss oral products and injections for skin changes, recovery and perceived energy.", "search_blob": "glutathione glutathione gsh l-glutathione liposomal glutathione reduced glutathione s-acetyl glutathione (sag) \u03b3-l-glutamyl-l-cysteinylglycine setria glutathione (branded oral form discussions) oxidized glutathione (gssg) glutathione gsh l-glutathione reduced glutathione liposomal glutathione s-acetyl glutathione (sag) skin lightening / melasma / pigmentation (discussed) detox / liver support discussion immune / nk-cell adjacency oxidative stress / redox balance recovery / athletic \u201cglow\u201d talk longevity / master-antioxidant narratives skin/hair detox discussion immune recovery skin lightening / melasma / pigmentation (discussed) detox / liver support discussion immune / nk-cell adjacency oxidative stress / redox balance recovery / athletic \u201cglow\u201d talk longevity / master-antioxidant narratives parkinson\u2019s iv and intranasal research adjacency fatty-liver / metabolic discussion iv med-spa wellness menus skin lightening / melasma / pigmentation (discussed) detox / liver support discussion immune / nk-cell adjacency oxidative stress / redox balance recovery / athletic \u201cglow\u201d talk longevity / master-antioxidant narratives glutathione is a small antioxidant peptide; people discuss oral products and injections for skin changes, recovery and perceived energy. oral users often notice little, or gi discomfort. iv reports include brief warmth, an unusual taste or flushing; energy and skin claims develop inconsistently and depend on the formulation. glutathione is an antioxidant the body makes, also discussed in oral, injected and other supplemental forms. accounts include skin or recovery changes, no benefit and unwanted effects; formulation, route and co-ingredients make comparisons difficult. antioxidant & detox discussion peptide systemic mostly systemic\u2014oral, liposomal and iv use dominate antioxidant, liver and skin talk; topical, airway and intranasal contexts remain route-specific. systemic whole-body circulating", "legal_class": null }, { "id": 86, "slug": "nac", "name": "NAC", "aliases": [ "N-acetylcysteine", "N-acetyl-L-cysteine", "N-acetyl cysteine", "Acetylcysteine", "Acetadote (IV brand discussions)", "Mucomyst (historical mucolytic / oral antidote brand talk)", "NALC", "GlyNAC (glycine + NAC stack name)", "N-AcCys" ], "type": "Non-peptide", "category": "Antioxidant & detox discussion", "goals_use_cases": [ "skin", "respiratory discussion", "detox discussion", "mental health adjacency", "liver support discussion", "respiratory / mucolytic discussion", "COPD / chronic bronchitis exacerbation talk", "bronchiectasis mucus-clearance talk", "liver support / post-alcohol detox discussion", "acetaminophen-overdose antidote (clinical framing only)", "glutathione / antioxidant support", "OCD / compulsion adjunct discussion", "BFRB (trichotillomania, skin-picking/excoriation, nail-biting)", "addiction / craving recovery adjacency (cannabis, nicotine, cocaine, alcohol, gambling pilots)", "mental health adjacency (schizophrenia negative symptoms, bipolar, autism irritability adjunct talk)", "male fertility / sperm-quality discussion", "immune / infection recovery talk", "longevity / aging-redox narratives (GlyNAC)", "hangover-product adjacency (regulatory / marketing history)", "athletic recovery / training-adjacent antioxidant talk (mixed, dose-dependent)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "nac", "N-acetylcysteine", "N-acetyl-L-cysteine", "N-acetyl cysteine", "Acetylcysteine", "Acetadote (IV brand discussions)", "respiratory / mucolytic discussion", "copd / chronic bronchitis exacerbation talk", "bronchiectasis mucus-clearance talk", "liver support / post-alcohol detox discussion", "acetaminophen-overdose antidote (clinical framing only)", "glutathione / antioxidant support" ], "feel_search": [ "respiratory / mucolytic discussion", "copd / chronic bronchitis exacerbation talk", "bronchiectasis mucus-clearance talk", "liver support / post-alcohol detox discussion", "acetaminophen-overdose antidote (clinical framing only)", "glutathione / antioxidant support" ], "summary": "NAC is N-acetylcysteine, a cysteine derivative used medically for mucus and acetaminophen poisoning, and as a supplement for other goals.", "search_blob": "nac nac n-acetylcysteine n-acetyl-l-cysteine n-acetyl cysteine acetylcysteine acetadote (iv brand discussions) mucomyst (historical mucolytic / oral antidote brand talk) nalc glynac (glycine + nac stack name) n-accys nac n-acetylcysteine n-acetyl-l-cysteine n-acetyl cysteine acetylcysteine acetadote (iv brand discussions) respiratory / mucolytic discussion copd / chronic bronchitis exacerbation talk bronchiectasis mucus-clearance talk liver support / post-alcohol detox discussion acetaminophen-overdose antidote (clinical framing only) glutathione / antioxidant support skin respiratory discussion detox discussion mental health adjacency liver support discussion respiratory / mucolytic discussion copd / chronic bronchitis exacerbation talk bronchiectasis mucus-clearance talk liver support / post-alcohol detox discussion acetaminophen-overdose antidote (clinical framing only) glutathione / antioxidant support ocd / compulsion adjunct discussion bfrb (trichotillomania, skin-picking/excoriation, nail-biting) addiction / craving recovery adjacency (cannabis, nicotine, cocaine, alcohol, gambling pilots) mental health adjacency (schizophrenia negative symptoms, bipolar, autism irritability adjunct talk) male fertility / sperm-quality discussion immune / infection recovery talk longevity / aging-redox narratives (glynac) hangover-product adjacency (regulatory / marketing history) athletic recovery / training-adjacent antioxidant talk (mixed, dose-dependent) respiratory / mucolytic discussion copd / chronic bronchitis exacerbation talk bronchiectasis mucus-clearance talk liver support / post-alcohol detox discussion acetaminophen-overdose antidote (clinical framing only) glutathione / antioxidant support nac is n-acetylcysteine, a cysteine derivative used medically for mucus and acetaminophen poisoning, and as a supplement for other goals. some notice easier mucus clearance; mood and intrusive-thought reports vary from marked calm to nothing. sulfur taste, nausea or stomach discomfort can appear early. nac is a cysteine derivative discussed for mucus clearance, glutathione support and compulsive urges. reports range from easier coughing or quieter thoughts to no benefit, stomach upset or emotional flattening. antioxidant & detox discussion non-peptide systemic systemic oral/iv cysteine donor; glutathione and system xc\u2212 talk. inhaled nac is more airway-local; topical use is local. systemic whole-body circulating", "legal_class": null }, { "id": 87, "slug": "ldn", "name": "Low-Dose Naltrexone (LDN)", "aliases": [ "LDN", "naltrexone low dose", "low dose naltrexone", "low-dose naltrexone", "ultra-low-dose naltrexone (ULDN)", "very low-dose naltrexone (VLDN)", "naltrexone (low-dose / compounding)", "4.5 mg naltrexone", "Bihari protocol naltrexone (historical LDN framing)" ], "type": "Non-peptide", "category": "Immune & inflammation adjacents", "goals_use_cases": [ "immune", "inflammation discussion", "pain discussion", "mood", "fibromyalgia discussion", "autoimmune discussion", "chronic fatigue discussion", "ME/CFS discussion", "Long COVID discussion", "sleep quality discussion", "gut inflammation / Crohn\u2019s discussion", "multiple sclerosis symptom discussion", "Hashimoto\u2019s / thyroid autoimmunity discussion", "CRPS / centralized pain discussion", "MCAS / allergy adjacency talk" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "ldn", "Low-Dose Naltrexone (LDN)", "low-dose-naltrexone-(ldn)", "naltrexone low dose", "low dose naltrexone", "low-dose naltrexone", "immune", "inflammation discussion", "pain discussion", "mood", "fibromyalgia discussion", "autoimmune discussion" ], "feel_search": [ "immune", "inflammation discussion", "pain discussion", "mood", "fibromyalgia discussion", "autoimmune discussion" ], "summary": "LDN means low-dose naltrexone, an opioid-receptor blocker used off label in much smaller amounts than standard addiction-treatment doses.", "search_blob": "low-dose naltrexone (ldn) ldn ldn naltrexone low dose low dose naltrexone low-dose naltrexone ultra-low-dose naltrexone (uldn) very low-dose naltrexone (vldn) naltrexone (low-dose / compounding) 4.5 mg naltrexone bihari protocol naltrexone (historical ldn framing) ldn low-dose naltrexone (ldn) low-dose-naltrexone-(ldn) naltrexone low dose low dose naltrexone low-dose naltrexone immune inflammation discussion pain discussion mood fibromyalgia discussion autoimmune discussion immune inflammation discussion pain discussion mood fibromyalgia discussion autoimmune discussion chronic fatigue discussion me/cfs discussion long covid discussion sleep quality discussion gut inflammation / crohn\u2019s discussion multiple sclerosis symptom discussion hashimoto\u2019s / thyroid autoimmunity discussion crps / centralized pain discussion mcas / allergy adjacency talk immune inflammation discussion pain discussion mood fibromyalgia discussion autoimmune discussion ldn means low-dose naltrexone, an opioid-receptor blocker used off label in much smaller amounts than standard addiction-treatment doses. early sleep effects vary from vivid dreams to insomnia, sometimes lasting beyond the first week. some report less aching later; others feel only side effects or stop because the tradeoff is poor. low-dose naltrexone is an opioid-receptor blocker discussed for chronic pain, fatigue and autoimmune symptoms. some report less aching or better sleep; others report no benefit, disturbing dreams, insomnia or jitteriness. immune & inflammation adjacents non-peptide systemic systemic oral immune / neuroimmune modulator\u2014not a local injection target. systemic whole-body circulating", "legal_class": null }, { "id": 88, "slug": "nr", "name": "NR (Nicotinamide Riboside)", "aliases": [ "Niagen-class discussion", "nicotinamide riboside", "Nicotinamide riboside", "Nicotinamide riboside chloride", "NR chloride", "NRCl", "Niagen", "Niagen NR", "Tru Niagen", "Vitamin B3 riboside form", "NRPT (NR + pterostilbene blend; Basis-class)", "Nicotinamide ribose (common misspelling)" ], "type": "Non-peptide", "category": "Longevity & cellular energy", "goals_use_cases": [ "longevity", "energy", "metabolic health", "longevity / healthy aging foundation", "cellular NAD+ support", "daytime energy / resilience (discussed)", "metabolic health (explored; mixed trials)", "mitochondrial / cellular energy narrative", "cognition / brain aging (exploratory)", "recovery after stress or training (discussed)", "Parkinson\u2019s / neuro research interest", "long-COVID / fatigue research interest", "anti-inflammatory NAD-metabolome framing" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "nr", "NR (Nicotinamide Riboside)", "nr-(nicotinamide-riboside)", "Nicotinamide riboside", "Nicotinamide riboside chloride", "NR chloride", "longevity / healthy aging foundation", "cellular nad+ support", "daytime energy / resilience (discussed)", "metabolic health (explored; mixed trials)", "mitochondrial / cellular energy narrative", "cognition / brain aging (exploratory)" ], "feel_search": [ "longevity / healthy aging foundation", "cellular nad+ support", "daytime energy / resilience (discussed)", "metabolic health (explored; mixed trials)", "mitochondrial / cellular energy narrative", "cognition / brain aging (exploratory)" ], "summary": "NR is nicotinamide riboside, a vitamin B3 form sold as an oral NAD+ precursor for energy and healthy aging.", "search_blob": "nr (nicotinamide riboside) nr niagen-class discussion nicotinamide riboside nicotinamide riboside nicotinamide riboside chloride nr chloride nrcl niagen niagen nr tru niagen vitamin b3 riboside form nrpt (nr + pterostilbene blend; basis-class) nicotinamide ribose (common misspelling) nr nr (nicotinamide riboside) nr-(nicotinamide-riboside) nicotinamide riboside nicotinamide riboside chloride nr chloride longevity / healthy aging foundation cellular nad+ support daytime energy / resilience (discussed) metabolic health (explored; mixed trials) mitochondrial / cellular energy narrative cognition / brain aging (exploratory) longevity energy metabolic health longevity / healthy aging foundation cellular nad+ support daytime energy / resilience (discussed) metabolic health (explored; mixed trials) mitochondrial / cellular energy narrative cognition / brain aging (exploratory) recovery after stress or training (discussed) parkinson\u2019s / neuro research interest long-covid / fatigue research interest anti-inflammatory nad-metabolome framing longevity / healthy aging foundation cellular nad+ support daytime energy / resilience (discussed) metabolic health (explored; mixed trials) mitochondrial / cellular energy narrative cognition / brain aging (exploratory) nr is nicotinamide riboside, a vitamin b3 form sold as an oral nad+ precursor for energy and healthy aging. many describe no acute effect; others report subtle energy or less fatigue, while some feel more tired or develop gi discomfort. blood nad+ changes are not a reliable feel gauge. nr (nicotinamide riboside) is a vitamin b3 form sold as an oral nad+ precursor. reports include more energy or clearer thinking, no change and worse fatigue or sleep; a blood nad+ increase does not establish a noticeable benefit or slower aging. longevity & cellular energy non-peptide systemic systemic oral nad+ precursor. systemic whole-body circulating", "legal_class": null }, { "id": 89, "slug": "collagen-peptides", "name": "Collagen peptides", "aliases": [ "hydrolyzed collagen", "collagen hydrolysate", "Hydrolyzed collagen", "Collagen hydrolysate", "Hydrolysed collagen", "Bioactive collagen peptides", "BCP (bioactive collagen peptides)", "Collagen peptide powder", "Type I/II/III collagen peptides", "Marine collagen peptides", "Bovine collagen peptides", "VERISOL", "FORTIGEL", "TENDOFORTE", "FORTIBONE", "BODYBALANCE" ], "type": "Peptide", "category": "Skin, hair & tissue remodeling", "goals_use_cases": [ "skin/hair", "joints & tendons", "recovery", "nails", "bone support (discussed)", "muscle recovery / body composition (discussed)", "connective-tissue training support", "longevity (lifestyle adjacent)", "performance continuity", "gut comfort (mixed / emerging talk)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "collagen-peptides", "collagen peptides", "collagenpeptides", "Hydrolyzed collagen", "Collagen hydrolysate", "Hydrolysed collagen", "skin/hair", "joints & tendons", "recovery", "nails", "bone support (discussed)", "muscle recovery / body composition (discussed)" ], "feel_search": [ "skin/hair", "joints & tendons", "recovery", "nails", "bone support (discussed)", "muscle recovery / body composition (discussed)" ], "summary": "Collagen peptides are hydrolyzed animal collagen fragments sold as food supplements for skin, joints and connective tissue.", "search_blob": "collagen peptides collagen-peptides hydrolyzed collagen collagen hydrolysate hydrolyzed collagen collagen hydrolysate hydrolysed collagen bioactive collagen peptides bcp (bioactive collagen peptides) collagen peptide powder type i/ii/iii collagen peptides marine collagen peptides bovine collagen peptides verisol fortigel tendoforte fortibone bodybalance collagen-peptides collagen peptides collagenpeptides hydrolyzed collagen collagen hydrolysate hydrolysed collagen skin/hair joints & tendons recovery nails bone support (discussed) muscle recovery / body composition (discussed) skin/hair joints & tendons recovery nails bone support (discussed) muscle recovery / body composition (discussed) connective-tissue training support longevity (lifestyle adjacent) performance continuity gut comfort (mixed / emerging talk) skin/hair joints & tendons recovery nails bone support (discussed) muscle recovery / body composition (discussed) collagen peptides are hydrolyzed animal collagen fragments sold as food supplements for skin, joints and connective tissue. reports include no skin change after a month, stronger nails in another user, and bloating in a long-term user. appearance, joint symptoms and gut tolerance are different outcomes. collagen peptides are hydrolyzed animal-protein fragments sold as oral supplements. people report softer skin, stronger nails or easier joints, but also no visible change and digestive discomfort. skin, hair & tissue remodeling peptide systemic oral digestion supplies circulating amino acids and small peptides; it does not target an injection site. systemic whole-body circulating", "legal_class": null }, { "id": 90, "slug": "creatine", "name": "Creatine monohydrate", "aliases": [ "creatine", "Creapure-class discussion", "CrM", "creatine monohydrate", "Creapure (branded monohydrate / quality shorthand)", "micronized creatine monohydrate", "creatine HCl / hydrochloride", "Kre-Alkalyn / buffered creatine", "creatine ethyl ester (CEE; historical form)", "creatine nitrate", "creatine magnesium chelate", "phosphocreatine (PCr; stored form in muscle)", "Cr (abbreviation in papers/forums)" ], "type": "Non-peptide", "category": "Performance staples (biohacking overlap)", "goals_use_cases": [ "muscle growth", "performance", "cognition", "muscle growth / lean mass", "strength & power", "high-intensity work capacity / repeat sprints", "performance (resistance training)", "recovery after hard sessions", "body composition (lean mass narratives)", "cognition / mental energy under stress", "sleep-deprivation / hypoxia performance talk", "vegan / low-meat dietary creatine gap", "women's health / peri-postmenopause + RT", "older adults / sarcopenia-adjacent training support", "bone-geometry / bone-health interest (with lifting)", "longevity / healthy-aging staple talk", "depression / brain-bioenergetics research interest" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "creatine", "Creatine monohydrate", "creatine-monohydrate", "CrM", "Creapure (branded monohydrate / quality shorthand)", "micronized creatine monohydrate", "muscle growth / lean mass", "strength & power", "high-intensity work capacity / repeat sprints", "performance (resistance training)", "recovery after hard sessions", "body composition (lean mass narratives)" ], "feel_search": [ "muscle growth / lean mass", "strength & power", "high-intensity work capacity / repeat sprints", "performance (resistance training)", "recovery after hard sessions", "body composition (lean mass narratives)" ], "summary": "Creatine monohydrate is a well-studied oral supplement that increases muscle creatine stores used in rapid energy supply.", "search_blob": "creatine monohydrate creatine creatine creapure-class discussion crm creatine monohydrate creapure (branded monohydrate / quality shorthand) micronized creatine monohydrate creatine hcl / hydrochloride kre-alkalyn / buffered creatine creatine ethyl ester (cee; historical form) creatine nitrate creatine magnesium chelate phosphocreatine (pcr; stored form in muscle) cr (abbreviation in papers/forums) creatine creatine monohydrate creatine-monohydrate crm creapure (branded monohydrate / quality shorthand) micronized creatine monohydrate muscle growth / lean mass strength & power high-intensity work capacity / repeat sprints performance (resistance training) recovery after hard sessions body composition (lean mass narratives) muscle growth performance cognition muscle growth / lean mass strength & power high-intensity work capacity / repeat sprints performance (resistance training) recovery after hard sessions body composition (lean mass narratives) cognition / mental energy under stress sleep-deprivation / hypoxia performance talk vegan / low-meat dietary creatine gap women's health / peri-postmenopause + rt older adults / sarcopenia-adjacent training support bone-geometry / bone-health interest (with lifting) longevity / healthy-aging staple talk depression / brain-bioenergetics research interest muscle growth / lean mass strength & power high-intensity work capacity / repeat sprints performance (resistance training) recovery after hard sessions body composition (lean mass narratives) creatine monohydrate is a well-studied oral supplement that increases muscle creatine stores used in rapid energy supply. a five-week user reports better training and recovery alongside bloating and weight fluctuations. separate users notice little when stopping, or mainly a scale-weight change. creatine monohydrate is an oral supplement discussed for repeated hard efforts and muscle fullness. some report better later sets or recovery; others notice little change or experience bloating and stomach problems. performance staples (biohacking overlap) non-peptide systemic systemic oral supplement that increases creatine stores, especially in skeletal muscle. systemic whole-body circulating", "legal_class": null }, { "id": 91, "slug": "pe-22-28", "name": "PE-22-28", "aliases": [ "Spadin-related peptide discussion", "PE2228", "Mini-Spadin", "PE 22-28", "PE-2228", "PE22-28", "Spadin-related peptide (residues 22\u201328)", "Spadin analog PE 22-28", "GVSWGLR peptide", "Gly-Val-Ser-Trp-Gly-Leu-Arg", "Sortilin propeptide fragment PE 22-28", "NTSR3/Sortilin-related TREK-1 ligand (spadin-lineage)" ], "type": "Peptide", "category": "Cognitive / nootropic peptides", "goals_use_cases": [ "mood", "cognition", "depression research discussion", "mood / emotional baseline", "depression research discussion (not an approved antidepressant)", "situational / grief-type mood support discussion (clinic lore)", "anxiety-adjacent stress resilience (discussed)", "cognition secondary to mood (brain fog / clarity)", "focus / mental clarity (anecdotal nootropic framing)", "neurogenesis / synaptogenesis interest (preclinical)", "post-stroke depression models (preclinical)", "stroke recovery / motor-cognitive endpoints (preclinical)", "TREK-1 (KCNK2) mechanism curiosity", "fast-onset alternative narrative vs multi-week SSRIs (community marketing)", "stack component with Selank / Semax / DSIP / Dihexa" ], "delivery_methods": [ "nasal" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "pe-22-28", "pe 22 28", "pe2228", "Mini-Spadin", "PE 22-28", "PE-2228", "mood / emotional baseline", "depression research discussion (not an approved antidepressant)", "situational / grief-type mood support discussion (clinic lore)", "anxiety-adjacent stress resilience (discussed)", "cognition secondary to mood (brain fog / clarity)", "focus / mental clarity (anecdotal nootropic framing)" ], "feel_search": [ "mood / emotional baseline", "depression research discussion (not an approved antidepressant)", "situational / grief-type mood support discussion (clinic lore)", "anxiety-adjacent stress resilience (discussed)", "cognition secondary to mood (brain fog / clarity)", "focus / mental clarity (anecdotal nootropic framing)" ], "summary": "PE-22-28, also called Mini-Spadin, is a synthetic seven-amino-acid research peptide discussed for mood.", "search_blob": "pe-22-28 pe-22-28 spadin-related peptide discussion pe2228 mini-spadin pe 22-28 pe-2228 pe22-28 spadin-related peptide (residues 22\u201328) spadin analog pe 22-28 gvswglr peptide gly-val-ser-trp-gly-leu-arg sortilin propeptide fragment pe 22-28 ntsr3/sortilin-related trek-1 ligand (spadin-lineage) pe-22-28 pe 22 28 pe2228 mini-spadin pe 22-28 pe-2228 mood / emotional baseline depression research discussion (not an approved antidepressant) situational / grief-type mood support discussion (clinic lore) anxiety-adjacent stress resilience (discussed) cognition secondary to mood (brain fog / clarity) focus / mental clarity (anecdotal nootropic framing) mood cognition depression research discussion mood / emotional baseline depression research discussion (not an approved antidepressant) situational / grief-type mood support discussion (clinic lore) anxiety-adjacent stress resilience (discussed) cognition secondary to mood (brain fog / clarity) focus / mental clarity (anecdotal nootropic framing) neurogenesis / synaptogenesis interest (preclinical) post-stroke depression models (preclinical) stroke recovery / motor-cognitive endpoints (preclinical) trek-1 (kcnk2) mechanism curiosity fast-onset alternative narrative vs multi-week ssris (community marketing) stack component with selank / semax / dsip / dihexa mood / emotional baseline depression research discussion (not an approved antidepressant) situational / grief-type mood support discussion (clinic lore) anxiety-adjacent stress resilience (discussed) cognition secondary to mood (brain fog / clarity) focus / mental clarity (anecdotal nootropic framing) pe-22-28, also called mini-spadin, is a synthetic seven-amino-acid research peptide discussed for mood. one user described easier task-starting and clearer thinking over days to weeks; another felt worse after almost three weeks. pe-22-28, also called mini-spadin, is an experimental peptide discussed for mood. reports include easier task-starting and enjoyment, no change, worsening mood, tiredness or overstimulation; human dose and long-term safety remain unestablished. pe-22-28 \u2260 spadin \u2260 full sortilin propeptide; mini-spadin is a brand/nickname, not a separate molecule. gray-market labels may underdose or mis-id. cognitive / nootropic peptides peptide systemic systemic cns focus \u2014 trek-1 potassium-channel block and mood/serotonergic excitability, not a local tissue-repair peptide. systemic whole-body circulating", "legal_class": null }, { "id": 92, "slug": "adipotide", "name": "Adipotide", "aliases": [ "FTPP", "proapoptotic peptide discussion", "Fat-Targeted Proapoptotic Peptide", "FTTP (common misspelling of FTPP)", "Prohibitin-TP01", "Prohibitin-targeting peptide 1", "TP01", "CKGGRAKDC-GG-D(KLAKLAK)2", "Arrowhead Adipotide / Ablaris adipotide (historical development)" ], "type": "Peptide", "category": "Metabolic / fat-loss peptides", "goals_use_cases": [ "fat loss", "fat loss / white adipose reduction (research framing)", "body composition / visceral + subcutaneous fat volume (primate imaging)", "obesity research models", "insulin resistance / metabolic marker research (animal)", "vascular-targeted adipose ablation concept", "prostate-cancer Phase 1 MTD context (historical, terminated)", "comparison talk vs GLP-1s, AOD-9604, Frag 176-191" ], "delivery_methods": [ "research injection discussion" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "adipotide", "FTPP", "Fat-Targeted Proapoptotic Peptide", "FTTP (common misspelling of FTPP)", "Prohibitin-TP01", "Prohibitin-targeting peptide 1", "fat loss / white adipose reduction (research framing)", "body composition / visceral + subcutaneous fat volume (primate imaging)", "obesity research models", "insulin resistance / metabolic marker research (animal)", "vascular-targeted adipose ablation concept", "prostate-cancer phase 1 mtd context (historical, terminated)" ], "feel_search": [ "fat loss / white adipose reduction (research framing)", "body composition / visceral + subcutaneous fat volume (primate imaging)", "obesity research models", "insulin resistance / metabolic marker research (animal)", "vascular-targeted adipose ablation concept", "prostate-cancer phase 1 mtd context (historical, terminated)" ], "summary": "Adipotide is an experimental peptide-based compound designed to target blood vessels feeding fat tissue.", "search_blob": "adipotide adipotide ftpp proapoptotic peptide discussion fat-targeted proapoptotic peptide fttp (common misspelling of ftpp) prohibitin-tp01 prohibitin-targeting peptide 1 tp01 ckggrakdc-gg-d(klaklak)2 arrowhead adipotide / ablaris adipotide (historical development) adipotide ftpp fat-targeted proapoptotic peptide fttp (common misspelling of ftpp) prohibitin-tp01 prohibitin-targeting peptide 1 fat loss / white adipose reduction (research framing) body composition / visceral + subcutaneous fat volume (primate imaging) obesity research models insulin resistance / metabolic marker research (animal) vascular-targeted adipose ablation concept prostate-cancer phase 1 mtd context (historical, terminated) fat loss fat loss / white adipose reduction (research framing) body composition / visceral + subcutaneous fat volume (primate imaging) obesity research models insulin resistance / metabolic marker research (animal) vascular-targeted adipose ablation concept prostate-cancer phase 1 mtd context (historical, terminated) comparison talk vs glp-1s, aod-9604, frag 176-191 fat loss / white adipose reduction (research framing) body composition / visceral + subcutaneous fat volume (primate imaging) obesity research models insulin resistance / metabolic marker research (animal) vascular-targeted adipose ablation concept prostate-cancer phase 1 mtd context (historical, terminated) adipotide is an experimental peptide-based compound designed to target blood vessels feeding fat tissue. the inspected log describes brief injection burning and persistent itching. early scale losses reversed with rehydration, while the author also took tirzepatide. adipotide is an experimental peptide-based compound designed to target white-fat blood vessels. human reports are sparse and confounded; animal fat-loss findings also include kidney injury. metabolic / fat-loss peptides peptide systemic systemic exposure; its proposed tissue targeting does not mean fat loss at the injection site. systemic whole-body circulating", "legal_class": null }, { "id": 93, "slug": "insulin", "name": "Insulin", "aliases": [ "humalog-class discussion", "slin (slang)", "Insulin (research/bodybuilding discourse)", "exogenous insulin", "Humalog / insulin lispro (rapid analog discussions)", "Novolog / NovoRapid / insulin aspart (rapid analog discussions)", "Apidra / insulin glulisine (rapid analog discussions)", "Humulin R / Novolin R / regular insulin (short-acting)", "Lantus / insulin glargine (basal long-acting talk)", "Levemir / insulin detemir (basal talk)", "Tresiba / insulin degludec (ultra-long basal contrast)", "Humulin N / NPH (intermediate; less common in pulse \u201cslin\u201d charts)" ], "type": "Peptide", "category": "Metabolic hormones", "goals_use_cases": [ "muscle", "muscle growth", "nutrient partitioning discussion", "muscle growth / hypertrophy discourse (anti-catabolic + nutrient uptake framing)", "post-workout recovery and glycogen replenishment (discussed)", "training-day fullness / pumps (discussed)", "glycogen supercompensation lore around hard sessions", "anti-catabolic / reduced proteolysis talk in the fed post-shot window", "performance enhancement / IPED polypharmacy stacks", "body recomposition and high-carb bulk support (community)", "GH-induced glucose-intolerance \u201cmanagement\u201d lore (advanced stacks)", "clinical diabetes glucose control (approved medical context \u2014 not a physique template)" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "insulin", "Insulin (research/bodybuilding discourse)", "slin (slang)", "exogenous insulin", "Humalog / insulin lispro (rapid analog discussions)", "Novolog / NovoRapid / insulin aspart (rapid analog discussions)", "muscle growth / hypertrophy discourse (anti-catabolic + nutrient uptake framing)", "nutrient partitioning discussion", "post-workout recovery and glycogen replenishment (discussed)", "training-day fullness / pumps (discussed)", "glycogen supercompensation lore around hard sessions", "anti-catabolic / reduced proteolysis talk in the fed post-shot window" ], "feel_search": [ "muscle growth / hypertrophy discourse (anti-catabolic + nutrient uptake framing)", "nutrient partitioning discussion", "post-workout recovery and glycogen replenishment (discussed)", "training-day fullness / pumps (discussed)", "glycogen supercompensation lore around hard sessions", "anti-catabolic / reduced proteolysis talk in the fed post-shot window" ], "summary": "Insulin is a blood-glucose-regulating hormone; rapid and long-acting medicines differ, and bodybuilding use carries serious hypoglycemia risk.", "search_blob": "insulin insulin humalog-class discussion slin (slang) insulin (research/bodybuilding discourse) exogenous insulin humalog / insulin lispro (rapid analog discussions) novolog / novorapid / insulin aspart (rapid analog discussions) apidra / insulin glulisine (rapid analog discussions) humulin r / novolin r / regular insulin (short-acting) lantus / insulin glargine (basal long-acting talk) levemir / insulin detemir (basal talk) tresiba / insulin degludec (ultra-long basal contrast) humulin n / nph (intermediate; less common in pulse \u201cslin\u201d charts) insulin insulin (research/bodybuilding discourse) slin (slang) exogenous insulin humalog / insulin lispro (rapid analog discussions) novolog / novorapid / insulin aspart (rapid analog discussions) muscle growth / hypertrophy discourse (anti-catabolic + nutrient uptake framing) nutrient partitioning discussion post-workout recovery and glycogen replenishment (discussed) training-day fullness / pumps (discussed) glycogen supercompensation lore around hard sessions anti-catabolic / reduced proteolysis talk in the fed post-shot window muscle muscle growth nutrient partitioning discussion muscle growth / hypertrophy discourse (anti-catabolic + nutrient uptake framing) post-workout recovery and glycogen replenishment (discussed) training-day fullness / pumps (discussed) glycogen supercompensation lore around hard sessions anti-catabolic / reduced proteolysis talk in the fed post-shot window performance enhancement / iped polypharmacy stacks body recomposition and high-carb bulk support (community) gh-induced glucose-intolerance \u201cmanagement\u201d lore (advanced stacks) clinical diabetes glucose control (approved medical context \u2014 not a physique template) muscle growth / hypertrophy discourse (anti-catabolic + nutrient uptake framing) nutrient partitioning discussion post-workout recovery and glycogen replenishment (discussed) training-day fullness / pumps (discussed) glycogen supercompensation lore around hard sessions anti-catabolic / reduced proteolysis talk in the fed post-shot window insulin is a blood-glucose-regulating hormone; rapid and long-acting medicines differ, and bodybuilding use carries serious hypoglycemia risk. gym users describe strong pumps and fullness, but the reviewed account also reported weakness and shaking despite an unchanged meal routine. effects and timing depend on the insulin formulation. insulin is a blood-glucose-regulating peptide hormone used medically for diabetes. short-term \u201cfull and hard\u201d training-day aesthetics on bulk food \u2014 water/glycogen confound large. metabolic hormones peptide systemic systemic \u2014 whole-body glucose disposal, amino-acid handling, and anti-lipolytic storage physiology. systemic whole-body circulating", "legal_class": null }, { "id": 94, "slug": "tb-4-fragments-other", "name": "TB-4 Fragment variants (non-TB-500 marketing)", "aliases": [ "TB4 frag", "thymosin fragments", "TB-4 Frag", "TB4-FRAG", "TB-4 FRAG", "Ac-SDKP", "N-acetyl-Ser-Asp-Lys-Pro", "N-acetyl-seryl-aspartyl-lysyl-proline", "TB4 Frag 1-4", "Thymosin Beta-4 Fragment (1-4)", "T\u03b24 N-terminal fragment", "Goralatide", "thymosin beta-4 fragments (non-TB-500)", "AcSDKP" ], "type": "Peptide", "category": "Healing & repair", "goals_use_cases": [ "recovery", "injury repair", "anti-fibrotic interest (discussed)", "inflammation (discussed)", "cardiac/organ repair narratives", "soft-tissue healing", "scar/fibrosis talk", "renal fibrosis research interest", "pulmonary fibrosis research interest", "hematopoietic / marrow-protection lore (goralatide history)", "performance continuity", "angiogenesis support narratives", "label/identity troubleshooting (TB4 vs TB-500 vs Ac-SDKP)" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Medium", "reach": "Mixed", "misspellings_search_terms": [ "tb-4-fragments-other", "tb 4 fragments other", "tb4fragmentsother", "TB-4 Fragment variants (non-TB-500 marketing)", "tb-4-fragment-variants-(non-tb-500-marketing)", "TB4 frag", "recovery", "injury repair", "anti-fibrotic interest (discussed)", "inflammation (discussed)", "cardiac/organ repair narratives", "soft-tissue healing" ], "feel_search": [ "recovery", "injury repair", "anti-fibrotic interest (discussed)", "inflammation (discussed)", "cardiac/organ repair narratives", "soft-tissue healing" ], "summary": "TB4 fragments are short pieces of thymosin beta-4; Ac-SDKP, TB-500 and full-length T\u03b24 are distinct identities despite overlapping labels.", "search_blob": "tb-4 fragment variants (non-tb-500 marketing) tb-4-fragments-other tb4 frag thymosin fragments tb-4 frag tb4-frag tb-4 frag ac-sdkp n-acetyl-ser-asp-lys-pro n-acetyl-seryl-aspartyl-lysyl-proline tb4 frag 1-4 thymosin beta-4 fragment (1-4) t\u03b24 n-terminal fragment goralatide thymosin beta-4 fragments (non-tb-500) acsdkp tb-4-fragments-other tb 4 fragments other tb4fragmentsother tb-4 fragment variants (non-tb-500 marketing) tb-4-fragment-variants-(non-tb-500-marketing) tb4 frag recovery injury repair anti-fibrotic interest (discussed) inflammation (discussed) cardiac/organ repair narratives soft-tissue healing recovery injury repair anti-fibrotic interest (discussed) inflammation (discussed) cardiac/organ repair narratives soft-tissue healing scar/fibrosis talk renal fibrosis research interest pulmonary fibrosis research interest hematopoietic / marrow-protection lore (goralatide history) performance continuity angiogenesis support narratives label/identity troubleshooting (tb4 vs tb-500 vs ac-sdkp) recovery injury repair anti-fibrotic interest (discussed) inflammation (discussed) cardiac/organ repair narratives soft-tissue healing tb4 fragments are short pieces of thymosin beta-4; ac-sdkp, tb-500 and full-length t\u03b24 are distinct identities despite overlapping labels. an oral tb4-frag/bpc-157 user reported no change after two weeks; responses to the combination cannot identify a fragment's effect. this page concerns thymosin beta-4 fragments, chiefly ac-sdkp, which differs from full-length t\u03b24 and the identified tb-500 fragment. oral-blend reports include easier movement, no change and serious unwanted symptoms; they cannot isolate ac-sdkp's effect. not a steroid, not a gh secretagogue, not interchangeable with tb-500 mg charts, not an fda-approved injury drug, not proven continuous lifelong therapy. healing & repair peptide mixed systemic ac-sdkp/tb4-fragment discussion spans anti-fibrotic research and unverified oral/subq recovery products; product identity is often unclear. mixed local systemic", "legal_class": null }, { "id": 95, "slug": "cjc-1295-dac", "name": "CJC-1295 with DAC", "aliases": [ "CJC DAC", "Drug Affinity Complex CJC", "CJC-1295 DAC", "DAC:GRF", "DAC-GRF", "CJC-1295 (with DAC)", "long-acting CJC-1295", "CJC1295 DAC", "CJC-1295", "albumin-binding CJC-1295", "ConjuChem DAC:GRF" ], "type": "Peptide", "category": "Growth hormone axis", "goals_use_cases": [ "muscle growth", "fat loss", "recovery", "body recomposition", "sleep", "performance", "anti-aging (discussed)", "IGF-1 support (discussed)", "lean mass preservation", "convenience / fewer injections", "sustained GH/IGF-1 elevation research" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "cjc-1295-dac", "cjc 1295 dac", "cjc1295dac", "CJC-1295 with DAC", "cjc-1295-with-dac", "CJC-1295 DAC", "muscle growth", "fat loss", "recovery", "body recomposition", "sleep", "performance" ], "feel_search": [ "muscle growth", "fat loss", "recovery", "body recomposition", "sleep", "performance" ], "summary": "CJC-1295 with DAC is a long-acting growth-hormone-releasing-hormone analogue designed to bind albumin and prolong exposure.", "search_blob": "cjc-1295 with dac cjc-1295-dac cjc dac drug affinity complex cjc cjc-1295 dac dac:grf dac-grf cjc-1295 (with dac) long-acting cjc-1295 cjc1295 dac cjc-1295 albumin-binding cjc-1295 conjuchem dac:grf cjc-1295-dac cjc 1295 dac cjc1295dac cjc-1295 with dac cjc-1295-with-dac cjc-1295 dac muscle growth fat loss recovery body recomposition sleep performance muscle growth fat loss recovery body recomposition sleep performance anti-aging (discussed) igf-1 support (discussed) lean mass preservation convenience / fewer injections sustained gh/igf-1 elevation research muscle growth fat loss recovery body recomposition sleep performance cjc-1295 with dac is a long-acting growth-hormone-releasing-hormone analogue designed to bind albumin and prolong exposure. one user reports water retention and stiff hands after a few weeks, then asks about persistence after stopping. the post does not establish when symptoms resolved. cjc-1295 with dac is a long-acting growth-hormone-releasing-hormone analogue. reports include better sleep, little visible change, water retention, stiff hands and fatigue; hormone elevation does not establish muscle or fat-loss benefits. growth hormone axis peptide systemic systemic \u2014 long-acting ghrh analog with a dac that binds albumin; multi-day gh stimulation and downstream igf-1 elevation, not local tissue repair. systemic whole-body circulating", "legal_class": null }, { "id": 96, "slug": "igf-1-des", "name": "IGF-1 DES", "aliases": [ "Des(1-3)IGF-1", "IGF1 DES", "DES(1-3) IGF-1", "des(1-3)IGF-I", "IGF-DES", "IGF DES 1,3", "IGF-1 DES 1-3", "des-IGF-1", "Des-IGF-1", "truncated IGF-1", "rHuDES(1-3)IGF-1" ], "type": "Peptide", "category": "Growth factors", "goals_use_cases": [ "muscle", "muscle growth", "localized growth discussion", "localized / site-specific muscle growth (primary discussion use)", "hypertrophy of lagging body parts (calves, arms, delts, chest talk)", "satellite-cell / hyperplasia lore (community + preclinical framing)", "post-workout anabolic signaling (discussed)", "recovery / training continuity in target muscle (discussed)", "soft-tissue / tendon-ligament repair discussion (often stacked)", "performance / bodybuilding specialization blocks", "body recomposition (discussed; confounded by stacks)", "contrast tool vs systemic IGF-1 LR3" ], "delivery_methods": [ "intramuscular" ], "discussion_popularity": "Medium", "reach": "Mixed", "misspellings_search_terms": [ "igf-1-des", "igf 1 des", "igf1des", "IGF-1 DES", "Des(1-3)IGF-1", "DES(1-3) IGF-1", "localized / site-specific muscle growth (primary discussion use)", "hypertrophy of lagging body parts (calves, arms, delts, chest talk)", "satellite-cell / hyperplasia lore (community + preclinical framing)", "post-workout anabolic signaling (discussed)", "recovery / training continuity in target muscle (discussed)", "soft-tissue / tendon-ligament repair discussion (often stacked)" ], "feel_search": [ "localized / site-specific muscle growth (primary discussion use)", "hypertrophy of lagging body parts (calves, arms, delts, chest talk)", "satellite-cell / hyperplasia lore (community + preclinical framing)", "post-workout anabolic signaling (discussed)", "recovery / training continuity in target muscle (discussed)", "soft-tissue / tendon-ligament repair discussion (often stacked)" ], "summary": "IGF-1 DES is a shortened IGF-1 research analog, discussed for muscle fullness and localized growth; the site-specific growth claim is not established in humans.", "search_blob": "igf-1 des igf-1-des des(1-3)igf-1 igf1 des des(1-3) igf-1 des(1-3)igf-i igf-des igf des 1,3 igf-1 des 1-3 des-igf-1 des-igf-1 truncated igf-1 rhudes(1-3)igf-1 igf-1-des igf 1 des igf1des igf-1 des des(1-3)igf-1 des(1-3) igf-1 localized / site-specific muscle growth (primary discussion use) hypertrophy of lagging body parts (calves, arms, delts, chest talk) satellite-cell / hyperplasia lore (community + preclinical framing) post-workout anabolic signaling (discussed) recovery / training continuity in target muscle (discussed) soft-tissue / tendon-ligament repair discussion (often stacked) muscle muscle growth localized growth discussion localized / site-specific muscle growth (primary discussion use) hypertrophy of lagging body parts (calves, arms, delts, chest talk) satellite-cell / hyperplasia lore (community + preclinical framing) post-workout anabolic signaling (discussed) recovery / training continuity in target muscle (discussed) soft-tissue / tendon-ligament repair discussion (often stacked) performance / bodybuilding specialization blocks body recomposition (discussed; confounded by stacks) contrast tool vs systemic igf-1 lr3 localized / site-specific muscle growth (primary discussion use) hypertrophy of lagging body parts (calves, arms, delts, chest talk) satellite-cell / hyperplasia lore (community + preclinical framing) post-workout anabolic signaling (discussed) recovery / training continuity in target muscle (discussed) soft-tissue / tendon-ligament repair discussion (often stacked) igf-1 des is a shortened igf-1 research analog, discussed for muscle fullness and localized growth; the site-specific growth claim is not established in humans. igf-1 des is a shortened growth-factor research peptide discussed for muscle growth. reports include fuller muscles or easier recovery, no noticeable benefit, and stronger pumps accompanied by poorer performance and soreness. growth factors peptide mixed mixed \u2014 usually discussed as a muscle-site injection, but systemic spillover and human des pharmacokinetics remain unresolved. mixed local systemic", "legal_class": null }, { "id": 97, "slug": "peg-igf-1", "name": "PEG-IGF-1", "aliases": [ "Pegylated IGF-1", "PEG-IGF-I", "PEGylated IGF-I", "PEG IGF-1", "PEG-IGF1", "Pegylated recombinant human IGF-1", "PEGylated recombinant human insulin-like growth factor-I", "RO5046013 (Roche clinical-research designation)", "PEG-rhIGF-I", "Long-acting IGF-1 (loose forum shorthand \u2014 not LR3)" ], "type": "Peptide", "category": "Growth factors", "goals_use_cases": [ "muscle growth", "recovery", "muscle growth / hypertrophy (discussed; sparse true-product logs)", "recovery / training continuity (discussed)", "performance", "anti-catabolism (discussed)", "soft-tissue / muscle repair talk (preclinical IM hook)", "longer-acting systemic IGF-1 exposure vs free rhIGF-1 or daily LR3", "longevity-adjacent IGF-pathway interest", "body recomposition (discussed; heavily confounded)", "dystrophy / muscle-pathology research backdrop (animal/clinical R&D, not physique approval)" ], "delivery_methods": [ "subcutaneous", "intramuscular" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "peg-igf-1", "peg igf 1", "pegigf1", "Pegylated IGF-1", "PEG-IGF-I", "PEGylated IGF-I", "muscle growth / hypertrophy (discussed; sparse true-product logs)", "recovery / training continuity (discussed)", "performance", "anti-catabolism (discussed)", "soft-tissue / muscle repair talk (preclinical im hook)", "longer-acting systemic igf-1 exposure vs free rhigf-1 or daily lr3" ], "feel_search": [ "muscle growth / hypertrophy (discussed; sparse true-product logs)", "recovery / training continuity (discussed)", "performance", "anti-catabolism (discussed)", "soft-tissue / muscle repair talk (preclinical im hook)", "longer-acting systemic igf-1 exposure vs free rhigf-1 or daily lr3" ], "summary": "PEG-IGF-1 is insulin-like growth factor 1 modified with polyethylene glycol to extend exposure; research-vial labels may not match studied material.", "search_blob": "peg-igf-1 peg-igf-1 pegylated igf-1 peg-igf-i pegylated igf-i peg igf-1 peg-igf1 pegylated recombinant human igf-1 pegylated recombinant human insulin-like growth factor-i ro5046013 (roche clinical-research designation) peg-rhigf-i long-acting igf-1 (loose forum shorthand \u2014 not lr3) peg-igf-1 peg igf 1 pegigf1 pegylated igf-1 peg-igf-i pegylated igf-i muscle growth / hypertrophy (discussed; sparse true-product logs) recovery / training continuity (discussed) performance anti-catabolism (discussed) soft-tissue / muscle repair talk (preclinical im hook) longer-acting systemic igf-1 exposure vs free rhigf-1 or daily lr3 muscle growth recovery muscle growth / hypertrophy (discussed; sparse true-product logs) recovery / training continuity (discussed) performance anti-catabolism (discussed) soft-tissue / muscle repair talk (preclinical im hook) longer-acting systemic igf-1 exposure vs free rhigf-1 or daily lr3 longevity-adjacent igf-pathway interest body recomposition (discussed; heavily confounded) dystrophy / muscle-pathology research backdrop (animal/clinical r&d, not physique approval) muscle growth / hypertrophy (discussed; sparse true-product logs) recovery / training continuity (discussed) performance anti-catabolism (discussed) soft-tissue / muscle repair talk (preclinical im hook) longer-acting systemic igf-1 exposure vs free rhigf-1 or daily lr3 peg-igf-1 is insulin-like growth factor 1 modified with polyethylene glycol to extend exposure; research-vial labels may not match studied material. the located peg-igf account combines it with peg-mgf; separate lr3 pump and appetite reports do not isolate peg-igf. peg-igf-1 is igf-1 modified with polyethylene glycol to prolong exposure. muscle and recovery discussion often confuses it with peg-mgf or lr3; the saved accounts do not establish an isolated, verified peg-igf-1 response. growth factors peptide systemic peg modification is intended to prolong circulating igf-1 exposure; local muscle-delivery findings come from separate animal experiments. systemic whole-body circulating", "legal_class": null }, { "id": 98, "slug": "thymalin", "name": "Thymalin", "aliases": [ "thymic bioregulator", "KEW peptide complex discussion", "Thymic bioregulator", "Thymus polypeptide complex", "Thymalinum", "Thymalin (calf thymus extract)", "Thymus polypeptide fraction", "KEW peptide complex (discussion)", "Khavinson thymic complex", "CAS 79621-14-0 (complex preparation, discussion)" ], "type": "Peptide", "category": "Longevity & bioregulators", "goals_use_cases": [ "immune", "longevity", "immune aging / immunosenescence (discussed)", "infection recovery support (discussed)", "T-cell balance (discussed)", "hematopoiesis support (discussed)", "geroprotection (research framing)", "post-illness convalescence (discussed)", "COVID-era adjunct discussion (Russian reports)", "annual immune tune-up (longevity stacks)", "lymphopenia / lymphocyte recovery narratives", "vs Thymosin Alpha-1 comparison shopping" ], "delivery_methods": [ "injection", "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "thymalin", "Thymic bioregulator", "Thymus polypeptide complex", "Thymalinum", "Thymalin (calf thymus extract)", "Thymus polypeptide fraction", "immune", "longevity", "immune aging / immunosenescence (discussed)", "infection recovery support (discussed)", "t-cell balance (discussed)", "hematopoiesis support (discussed)" ], "feel_search": [ "immune", "longevity", "immune aging / immunosenescence (discussed)", "infection recovery support (discussed)", "t-cell balance (discussed)", "hematopoiesis support (discussed)" ], "summary": "Thymalin is a calf-thymus peptide extract containing multiple fractions, used in the Russian immune-bioregulator tradition.", "search_blob": "thymalin thymalin thymic bioregulator kew peptide complex discussion thymic bioregulator thymus polypeptide complex thymalinum thymalin (calf thymus extract) thymus polypeptide fraction kew peptide complex (discussion) khavinson thymic complex cas 79621-14-0 (complex preparation, discussion) thymalin thymic bioregulator thymus polypeptide complex thymalinum thymalin (calf thymus extract) thymus polypeptide fraction immune longevity immune aging / immunosenescence (discussed) infection recovery support (discussed) t-cell balance (discussed) hematopoiesis support (discussed) immune longevity immune aging / immunosenescence (discussed) infection recovery support (discussed) t-cell balance (discussed) hematopoiesis support (discussed) geroprotection (research framing) post-illness convalescence (discussed) covid-era adjunct discussion (russian reports) annual immune tune-up (longevity stacks) lymphopenia / lymphocyte recovery narratives vs thymosin alpha-1 comparison shopping immune longevity immune aging / immunosenescence (discussed) infection recovery support (discussed) t-cell balance (discussed) hematopoiesis support (discussed) thymalin is a calf-thymus peptide extract containing multiple fractions, used in the russian immune-bioregulator tradition. one user reported staying active with a shorter-feeling chest cold, while a separate commenter reported a migraine-like headache. thymalin is a calf-thymus extract containing multiple peptide fractions. people discuss illness recovery and immune aging, with reports of staying active during illness, little noticeable effect and headache; the accounts do not establish infection prevention. longevity & bioregulators peptide systemic systemic \u2014 multi-peptide thymic bioregulator framed for immune, blood-cell, and age-related immune regulation, not a local soft-tissue injury agent. systemic whole-body circulating", "legal_class": null }, { "id": 99, "slug": "vilon", "name": "Vilon", "aliases": [ "KE peptide", "thymus bioregulator Vilon", "Lys-Glu", "L-Lys-L-Glu", "lysylglutamic acid", "lysyl glutamate", "Vilon\u00ae (research / originator trade discussion)", "cytogen KE", "synthetic thymic dipeptide Lys-Glu" ], "type": "Peptide", "category": "Longevity & bioregulators", "goals_use_cases": [ "immune", "longevity", "immune modulation / immunosenescence (discussed)", "thymus / T-cell differentiation support (preclinical framing)", "longevity / geroprotection (rodent lineage)", "cellular aging and chromatin / gene-expression research", "anti-inflammaging narratives", "recovery continuity and infection-season resilience (community)", "coagulation / hemostasis marker research (small human cohort)", "multi-bioregulator longevity stacks (not solo hero compound)" ], "delivery_methods": [ "oral", "injection discussion" ], "discussion_popularity": "Medium", "reach": "Mixed", "misspellings_search_terms": [ "vilon", "KE peptide", "Lys-Glu", "L-Lys-L-Glu", "lysylglutamic acid", "lysyl glutamate", "immune modulation / immunosenescence (discussed)", "thymus / t-cell differentiation support (preclinical framing)", "longevity / geroprotection (rodent lineage)", "cellular aging and chromatin / gene-expression research", "anti-inflammaging narratives", "recovery continuity and infection-season resilience (community)" ], "feel_search": [ "immune modulation / immunosenescence (discussed)", "thymus / t-cell differentiation support (preclinical framing)", "longevity / geroprotection (rodent lineage)", "cellular aging and chromatin / gene-expression research", "anti-inflammaging narratives", "recovery continuity and infection-season resilience (community)" ], "summary": "Vilon is the synthetic Lys-Glu dipeptide from thymus-bioregulator research, discussed for immune and aging-related interests.", "search_blob": "vilon vilon ke peptide thymus bioregulator vilon lys-glu l-lys-l-glu lysylglutamic acid lysyl glutamate vilon\u00ae (research / originator trade discussion) cytogen ke synthetic thymic dipeptide lys-glu vilon ke peptide lys-glu l-lys-l-glu lysylglutamic acid lysyl glutamate immune modulation / immunosenescence (discussed) thymus / t-cell differentiation support (preclinical framing) longevity / geroprotection (rodent lineage) cellular aging and chromatin / gene-expression research anti-inflammaging narratives recovery continuity and infection-season resilience (community) immune longevity immune modulation / immunosenescence (discussed) thymus / t-cell differentiation support (preclinical framing) longevity / geroprotection (rodent lineage) cellular aging and chromatin / gene-expression research anti-inflammaging narratives recovery continuity and infection-season resilience (community) coagulation / hemostasis marker research (small human cohort) multi-bioregulator longevity stacks (not solo hero compound) immune modulation / immunosenescence (discussed) thymus / t-cell differentiation support (preclinical framing) longevity / geroprotection (rodent lineage) cellular aging and chromatin / gene-expression research anti-inflammaging narratives recovery continuity and infection-season resilience (community) vilon is the synthetic lys-glu dipeptide from thymus-bioregulator research, discussed for immune and aging-related interests. one vip/vilon user initially described much more energy and clearer thinking, then later said the benefit was not durable. vilon is a synthetic lys-glu peptide studied in thymus-bioregulator research. users describe less soreness or clearer thinking, absent benefit and an early combination response that later faded. longevity & bioregulators peptide mixed mixed \u2014 a thymus-derived research concept discussed for systemic immune and aging-related effects; selective thymus delivery and human exposure remain unresolved. mixed local systemic", "legal_class": null }, { "id": 100, "slug": "cartalax", "name": "Cartalax", "aliases": [ "cartilage bioregulator", "AED peptide discussion", "AED peptide", "Ala-Glu-Asp", "Alanyl-glutamyl-aspartic acid", "T-31", "AC-4", "AC4", "Cartalax Cytogen", "Khavinson cartilage peptide", "cartilage and bone tissue bioregulator" ], "type": "Peptide", "category": "Longevity & bioregulators", "goals_use_cases": [ "joints & tendons", "recovery", "cartilage / connective tissue (discussed)", "osteoarthritis / wear-and-tear narratives", "longevity / musculoskeletal aging", "mobility & morning stiffness (community)", "bone\u2013cartilage axis discussion (product literature)", "inflammation moderation (discussed)", "performance continuity under joint load", "post-injury or post-fracture rehab adjunct (discussed)", "spinal osteochondrosis / degenerative spine talk (Russian product literature)" ], "delivery_methods": [ "oral", "injection discussion" ], "discussion_popularity": "Medium", "reach": "Mixed", "misspellings_search_terms": [ "cartalax", "AED peptide", "Ala-Glu-Asp", "Alanyl-glutamyl-aspartic acid", "T-31", "AC-4", "joints & tendons", "recovery", "cartilage / connective tissue (discussed)", "osteoarthritis / wear-and-tear narratives", "longevity / musculoskeletal aging", "mobility & morning stiffness (community)" ], "feel_search": [ "joints & tendons", "recovery", "cartilage / connective tissue (discussed)", "osteoarthritis / wear-and-tear narratives", "longevity / musculoskeletal aging", "mobility & morning stiffness (community)" ], "summary": "Cartalax is the synthetic tripeptide AED, marketed as a cartilage and bone bioregulator for joint-related goals.", "search_blob": "cartalax cartalax cartilage bioregulator aed peptide discussion aed peptide ala-glu-asp alanyl-glutamyl-aspartic acid t-31 ac-4 ac4 cartalax cytogen khavinson cartilage peptide cartilage and bone tissue bioregulator cartalax aed peptide ala-glu-asp alanyl-glutamyl-aspartic acid t-31 ac-4 joints & tendons recovery cartilage / connective tissue (discussed) osteoarthritis / wear-and-tear narratives longevity / musculoskeletal aging mobility & morning stiffness (community) joints & tendons recovery cartilage / connective tissue (discussed) osteoarthritis / wear-and-tear narratives longevity / musculoskeletal aging mobility & morning stiffness (community) bone\u2013cartilage axis discussion (product literature) inflammation moderation (discussed) performance continuity under joint load post-injury or post-fracture rehab adjunct (discussed) spinal osteochondrosis / degenerative spine talk (russian product literature) joints & tendons recovery cartilage / connective tissue (discussed) osteoarthritis / wear-and-tear narratives longevity / musculoskeletal aging mobility & morning stiffness (community) cartalax is the synthetic tripeptide aed, marketed as a cartilage and bone bioregulator for joint-related goals. in the same thread, one person reports marked hip-arthritis relief while another reports none after two courses. neither account proves cartilage regrowth. cartalax is the synthetic tripeptide aed, discussed for joint comfort and cartilage-related goals. reports range from marked relief to no change after repeated courses; improved comfort does not establish cartilage regrowth. longevity & bioregulators peptide mixed discussed for cartilage and connective tissue, with oral or injectable exposure rather than proven local delivery. mixed local systemic", "legal_class": null }, { "id": 101, "slug": "vesugen", "name": "Vesugen", "aliases": [ "vascular bioregulator", "KED peptide", "KED", "Lys-Glu-Asp", "Lysyl-glutamyl-aspartic acid", "H-Lys-Glu-Asp-OH", "Vezugen (Russian transliteration)", "Vesogen (common misspelling)", "T-38 (research designation)", "Khavinson vascular tripeptide", "vascular cytogen (Khavinson class)" ], "type": "Peptide", "category": "Longevity & bioregulators", "goals_use_cases": [ "blood flow", "gym pumps", "erections", "vascular discussion", "longevity", "vascular health / endothelial support (discussed)", "longevity / geroprotection narratives", "circulation / microcirculation / blood-flow talk", "cardiovascular aging interest", "atherosclerosis / arterial-insufficiency research context", "vasculogenic erectile-function discussion", "cerebral perfusion / cognitive-support stacks (secondary)", "performance continuity via vascular comfort (anecdotal)", "cytogen \u2192 cytomax vascular sequencing (with Ventfort)" ], "delivery_methods": [ "oral", "injection discussion" ], "discussion_popularity": "Emerging", "reach": "Mixed", "misspellings_search_terms": [ "vesugen", "KED peptide", "KED", "Lys-Glu-Asp", "Lysyl-glutamyl-aspartic acid", "H-Lys-Glu-Asp-OH", "russian cialis", "vesugen peptide", "vascular health / endothelial support (discussed)", "longevity / geroprotection narratives", "circulation / microcirculation / blood-flow talk", "cardiovascular aging interest", "atherosclerosis / arterial-insufficiency research context", "vasculogenic erectile-function discussion", "blood flow", "gym pumps", "veins", "cardio", "erections", "brain fog", "cialis" ], "feel_search": [ "vascular health / endothelial support (discussed)", "longevity / geroprotection narratives", "circulation / microcirculation / blood-flow talk", "cardiovascular aging interest", "atherosclerosis / arterial-insufficiency research context", "vasculogenic erectile-function discussion", "blood flow", "gym pumps", "veins", "cardio", "erections", "brain fog", "cialis" ], "summary": "Vesugen is the synthetic tripeptide KED, discussed for circulation, gym pumps and erection-related blood flow. Reports include more visible veins, no noticeable change, and\u2026", "search_blob": "vesugen vesugen vascular bioregulator ked peptide ked lys-glu-asp lysyl-glutamyl-aspartic acid h-lys-glu-asp-oh vezugen (russian transliteration) vesogen (common misspelling) t-38 (research designation) khavinson vascular tripeptide vascular cytogen (khavinson class) vesugen ked peptide ked lys-glu-asp lysyl-glutamyl-aspartic acid h-lys-glu-asp-oh russian cialis vesugen peptide vascular health / endothelial support (discussed) longevity / geroprotection narratives circulation / microcirculation / blood-flow talk cardiovascular aging interest atherosclerosis / arterial-insufficiency research context vasculogenic erectile-function discussion blood flow gym pumps veins cardio erections brain fog cialis blood flow gym pumps erections vascular discussion longevity vascular health / endothelial support (discussed) longevity / geroprotection narratives circulation / microcirculation / blood-flow talk cardiovascular aging interest atherosclerosis / arterial-insufficiency research context vasculogenic erectile-function discussion cerebral perfusion / cognitive-support stacks (secondary) performance continuity via vascular comfort (anecdotal) cytogen \u2192 cytomax vascular sequencing (with ventfort) vascular health / endothelial support (discussed) longevity / geroprotection narratives circulation / microcirculation / blood-flow talk cardiovascular aging interest atherosclerosis / arterial-insufficiency research context vasculogenic erectile-function discussion blood flow gym pumps veins cardio erections brain fog cialis vesugen is the synthetic tripeptide ked, discussed for circulation, gym pumps and erection-related blood flow. reports include more visible veins, no noticeable change, and\u2026 vesugen is the synthetic tripeptide ked, discussed for circulation, gym pumps and erection-related blood flow. reports include more visible veins, no noticeable change, and weakness or brain fog; visible veins do not establish healthier vessels. longevity & bioregulators peptide mixed mixed \u2014 vascular-targeted framing, but oral, sublingual and subq use is systemic rather than a local vessel treatment. mixed local systemic", "legal_class": null }, { "id": 102, "slug": "cardiogen", "name": "Cardiogen", "aliases": [ "heart bioregulator", "Ala-Glu-Asp-Arg discussion", "AEDR", "Ala-Glu-Asp-Arg", "H-Ala-Glu-Asp-Arg-OH", "AEDR tetrapeptide", "cardiac bioregulator peptide", "Cardiogen peptide", "Khavinson AEDR", "Khavinson heart tetrapeptide", "cardiac Cytogen (synthetic class talk)", "T-30 (vendor shorthand, inconsistent)", "AED (vendor shorthand \u2014 sometimes confuses sequence count)", "PubChem CID 11583989 (listed on secondary research pages)" ], "type": "Peptide", "category": "Longevity & bioregulators", "goals_use_cases": [ "cardiovascular discussion", "longevity", "cardiovascular discussion / heart-tissue bioregulator framing", "longevity / healthspan multi-organ calendars", "heart tissue repair / remodeling interest (research context)", "cardiac scar / fibroblast-modulation narratives", "endurance / circulation / oxygen-use feel (community)", "post-stress or post-PED cardio recovery (community)", "fibroblast / inflammaging / SASP research interest", "aging cardiovascular support narratives", "post-MI / ischemic recovery talk (preclinical + marketing only)", "blood-pressure comfort narratives (anecdotal, not Rx substitute)", "vs Vesugen / Chelohart / Cardiolax identity searches", "PCT-adjacent heart support talk in hard-training circles" ], "delivery_methods": [ "oral", "injection discussion" ], "discussion_popularity": "Emerging", "reach": "Mixed", "misspellings_search_terms": [ "cardiogen", "AEDR", "Ala-Glu-Asp-Arg", "H-Ala-Glu-Asp-Arg-OH", "AEDR tetrapeptide", "heart bioregulator", "cardiovascular discussion / heart-tissue bioregulator framing", "longevity / healthspan multi-organ calendars", "heart tissue repair / remodeling interest (research context)", "cardiac scar / fibroblast-modulation narratives", "endurance / circulation / oxygen-use feel (community)", "post-stress or post-ped cardio recovery (community)" ], "feel_search": [ "cardiovascular discussion / heart-tissue bioregulator framing", "longevity / healthspan multi-organ calendars", "heart tissue repair / remodeling interest (research context)", "cardiac scar / fibroblast-modulation narratives", "endurance / circulation / oxygen-use feel (community)", "post-stress or post-ped cardio recovery (community)" ], "summary": "Cardiogen is the synthetic tetrapeptide AEDR, marketed as a heart bioregulator and studied in preclinical tissue research.", "search_blob": "cardiogen cardiogen heart bioregulator ala-glu-asp-arg discussion aedr ala-glu-asp-arg h-ala-glu-asp-arg-oh aedr tetrapeptide cardiac bioregulator peptide cardiogen peptide khavinson aedr khavinson heart tetrapeptide cardiac cytogen (synthetic class talk) t-30 (vendor shorthand, inconsistent) aed (vendor shorthand \u2014 sometimes confuses sequence count) pubchem cid 11583989 (listed on secondary research pages) cardiogen aedr ala-glu-asp-arg h-ala-glu-asp-arg-oh aedr tetrapeptide heart bioregulator cardiovascular discussion / heart-tissue bioregulator framing longevity / healthspan multi-organ calendars heart tissue repair / remodeling interest (research context) cardiac scar / fibroblast-modulation narratives endurance / circulation / oxygen-use feel (community) post-stress or post-ped cardio recovery (community) cardiovascular discussion longevity cardiovascular discussion / heart-tissue bioregulator framing longevity / healthspan multi-organ calendars heart tissue repair / remodeling interest (research context) cardiac scar / fibroblast-modulation narratives endurance / circulation / oxygen-use feel (community) post-stress or post-ped cardio recovery (community) fibroblast / inflammaging / sasp research interest aging cardiovascular support narratives post-mi / ischemic recovery talk (preclinical + marketing only) blood-pressure comfort narratives (anecdotal, not rx substitute) vs vesugen / chelohart / cardiolax identity searches pct-adjacent heart support talk in hard-training circles cardiovascular discussion / heart-tissue bioregulator framing longevity / healthspan multi-organ calendars heart tissue repair / remodeling interest (research context) cardiac scar / fibroblast-modulation narratives endurance / circulation / oxygen-use feel (community) post-stress or post-ped cardio recovery (community) cardiogen is the synthetic tetrapeptide aedr, marketed as a heart bioregulator and studied in preclinical tissue research. one user reports higher nighttime resting heart rate and an improvement after changing timing; another reports lower heart rate and blood pressure. cardiogen is the synthetic aedr peptide studied in cardiac-tissue research. reports include easier exertion, uncertain or absent benefit, and higher or lower resting heart rate; they do not establish heart repair. longevity & bioregulators peptide mixed cardiac-tissue research and whole-body community use; tissue selectivity does not establish targeted delivery. mixed local systemic", "legal_class": null }, { "id": 103, "slug": "livagen", "name": "Livagen", "aliases": [ "liver bioregulator", "KEDA peptide discussion", "KEDA", "KEDA peptide", "Lys-Glu-Asp-Ala", "H-Lys-Glu-Asp-Ala-OH", "H-KEDA-OH", "Livagen peptide", "Khavinson liver tetrapeptide", "SCHEMBL5967826", "lysyl-glutamyl-aspartylalanine" ], "type": "Peptide", "category": "Longevity & bioregulators", "goals_use_cases": [ "liver support discussion", "longevity", "longevity / geroprotector stacks", "hepatoprotection (preclinical / discussed)", "immune aging / lymphocyte chromatin talk", "chromatin / gene-expression narratives", "digestive enzyme aging discussion", "antioxidant / hepatic stress models", "post-alcohol or bulk \u2018liver load\u2019 recovery talk", "enkephalinase / endogenous opioid enzyme talk", "multi-organ bioregulator kits (liver slot)", "vs Ovagen / Svetinorm dual-liver framing" ], "delivery_methods": [ "oral", "injection discussion" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "livagen", "KEDA", "KEDA peptide", "Lys-Glu-Asp-Ala", "H-Lys-Glu-Asp-Ala-OH", "H-KEDA-OH", "liver support discussion", "longevity / geroprotector stacks", "hepatoprotection (preclinical / discussed)", "immune aging / lymphocyte chromatin talk", "chromatin / gene-expression narratives", "digestive enzyme aging discussion" ], "feel_search": [ "liver support discussion", "longevity / geroprotector stacks", "hepatoprotection (preclinical / discussed)", "immune aging / lymphocyte chromatin talk", "chromatin / gene-expression narratives", "digestive enzyme aging discussion" ], "summary": "Livagen is the synthetic four-amino-acid peptide KEDA, studied in preclinical liver-cell work and discussed as a liver or aging bioregulator.", "search_blob": "livagen livagen liver bioregulator keda peptide discussion keda keda peptide lys-glu-asp-ala h-lys-glu-asp-ala-oh h-keda-oh livagen peptide khavinson liver tetrapeptide schembl5967826 lysyl-glutamyl-aspartylalanine livagen keda keda peptide lys-glu-asp-ala h-lys-glu-asp-ala-oh h-keda-oh liver support discussion longevity / geroprotector stacks hepatoprotection (preclinical / discussed) immune aging / lymphocyte chromatin talk chromatin / gene-expression narratives digestive enzyme aging discussion liver support discussion longevity longevity / geroprotector stacks hepatoprotection (preclinical / discussed) immune aging / lymphocyte chromatin talk chromatin / gene-expression narratives digestive enzyme aging discussion antioxidant / hepatic stress models post-alcohol or bulk \u2018liver load\u2019 recovery talk enkephalinase / endogenous opioid enzyme talk multi-organ bioregulator kits (liver slot) vs ovagen / svetinorm dual-liver framing liver support discussion longevity / geroprotector stacks hepatoprotection (preclinical / discussed) immune aging / lymphocyte chromatin talk chromatin / gene-expression narratives digestive enzyme aging discussion livagen is the synthetic four-amino-acid peptide keda, studied in preclinical liver-cell work and discussed as a liver or aging bioregulator. reports are sparse and conflicting: claimed liver or recovery benefits are often stacked, while one user described severe anxiety and heart symptoms. a reliable typical feel is not established. livagen is the synthetic peptide keda, discussed for liver support and aging. reports range from energy or liver-marker changes in stacks to no noticeable benefit and severe anxiety or heart symptoms; a typical response is not established. longevity & bioregulators peptide systemic systemic \u2014 liver-directed marketing does not establish liver-selective delivery in humans. systemic whole-body circulating", "legal_class": null }, { "id": 104, "slug": "ovagen", "name": "Ovagen", "aliases": [ "liver/GI bioregulator discussions vary by source", "Ovagen bioregulator", "Glu-Asp-Leu", "EDL tripeptide", "EDL", "glutamyl-aspartyl-leucine", "Ovagen Cytogen", "liver/GI bioregulator (Khavinson class)", "Ovagen lingual", "AC-3 complex (vendor identity debates)", "C15H25N3O8 (~375.37\u2013375.4 g/mol free EDL form)", "SCHEMBL5329396 / CHEBI:137252 / PubChem CID 444128 (EDL listings vary by source)", "CAS 9046-70-2 (listed on some research-chem pages \u2014 verify; not a universal registry truth)" ], "type": "Peptide", "category": "Longevity & bioregulators", "goals_use_cases": [ "gut health", "liver support discussion", "gut health / GI mucosa support (discussed)", "longevity / organ bioregulator calendars", "detoxification capacity narratives", "metabolic / bile / fat-meal tolerance talk", "age-related hepatic decline (discussed)", "NAFLD / fatty-liver adjunct talk", "post-alcohol or medication hepatic-stress recovery (discussed)", "bodybuilding / oral-compound post-cycle liver talk", "post-hepatitis recovery adjunct (discussed; medical care primary)", "chemo / antibiotic / toxin mucosal-protection narratives (research framing)", "gut\u2013liver axis optimization talk", "inflammatory-bowel adjunct narratives (sparse evidence; medical care primary)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "ovagen", "Ovagen bioregulator", "Glu-Asp-Leu", "EDL tripeptide", "EDL", "glutamyl-aspartyl-leucine", "gut health / gi mucosa support (discussed)", "liver support discussion", "longevity / organ bioregulator calendars", "detoxification capacity narratives", "metabolic / bile / fat-meal tolerance talk", "age-related hepatic decline (discussed)" ], "feel_search": [ "gut health / gi mucosa support (discussed)", "liver support discussion", "longevity / organ bioregulator calendars", "detoxification capacity narratives", "metabolic / bile / fat-meal tolerance talk", "age-related hepatic decline (discussed)" ], "summary": "Ovagen is a synthetic three-amino-acid peptide sold as a liver bioregulator; it is distinct from mixed liver-extract capsules.", "search_blob": "ovagen ovagen liver/gi bioregulator discussions vary by source ovagen bioregulator glu-asp-leu edl tripeptide edl glutamyl-aspartyl-leucine ovagen cytogen liver/gi bioregulator (khavinson class) ovagen lingual ac-3 complex (vendor identity debates) c15h25n3o8 (~375.37\u2013375.4 g/mol free edl form) schembl5329396 / chebi:137252 / pubchem cid 444128 (edl listings vary by source) cas 9046-70-2 (listed on some research-chem pages \u2014 verify; not a universal registry truth) ovagen ovagen bioregulator glu-asp-leu edl tripeptide edl glutamyl-aspartyl-leucine gut health / gi mucosa support (discussed) liver support discussion longevity / organ bioregulator calendars detoxification capacity narratives metabolic / bile / fat-meal tolerance talk age-related hepatic decline (discussed) gut health liver support discussion gut health / gi mucosa support (discussed) longevity / organ bioregulator calendars detoxification capacity narratives metabolic / bile / fat-meal tolerance talk age-related hepatic decline (discussed) nafld / fatty-liver adjunct talk post-alcohol or medication hepatic-stress recovery (discussed) bodybuilding / oral-compound post-cycle liver talk post-hepatitis recovery adjunct (discussed; medical care primary) chemo / antibiotic / toxin mucosal-protection narratives (research framing) gut\u2013liver axis optimization talk inflammatory-bowel adjunct narratives (sparse evidence; medical care primary) gut health / gi mucosa support (discussed) liver support discussion longevity / organ bioregulator calendars detoxification capacity narratives metabolic / bile / fat-meal tolerance talk age-related hepatic decline (discussed) ovagen is a synthetic three-amino-acid peptide sold as a liver bioregulator; it is distinct from mixed liver-extract capsules. often little is noticed beyond possible gi discomfort or injection sting. claimed liver or digestion improvements are difficult to separate from other products and changing labs. ovagen is usually identified as the synthetic tripeptide edl. reports include easier digestion, less post-meal heaviness or bloating, and no noticeable change; changing products and lifestyles make its contribution difficult to isolate. longevity & bioregulators peptide systemic systemic oral/injected exposure is discussed; liver/gi targeting is a research or marketing claim, not proven selective delivery. systemic whole-body circulating", "legal_class": null }, { "id": 105, "slug": "prostamax", "name": "Prostamax", "aliases": [ "prostate bioregulator", "KEDP peptide", "KEDP", "Lys-Glu-Asp-Pro", "Lysyl-glutamyl-aspartyl-proline", "H-Lys-Glu-Asp-Pro-OH", "Prostamax peptide", "synthetic prostate tetrapeptide", "Khavinson prostate peptide" ], "type": "Peptide", "category": "Longevity & bioregulators", "goals_use_cases": [ "men's health discussion", "prostate support narratives", "urinary comfort / nocturia interest (community)", "chronic prostatitis research context (preclinical)", "BPH-adjacent talk (community; evidence mostly extract or animal)", "longevity / chromatin-aging interest", "inflammation and tissue-repair narratives", "urologic wellness interest (community)", "libido / sexual-function halo (often stacked or extract-confounded)" ], "delivery_methods": [ "oral", "injection discussion" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "prostamax", "KEDP", "KEDP peptide", "Lys-Glu-Asp-Pro", "Lysyl-glutamyl-aspartyl-proline", "H-Lys-Glu-Asp-Pro-OH", "men's health discussion", "prostate support narratives", "urinary comfort / nocturia interest (community)", "chronic prostatitis research context (preclinical)", "bph-adjacent talk (community; evidence mostly extract or animal)", "longevity / chromatin-aging interest" ], "feel_search": [ "men's health discussion", "prostate support narratives", "urinary comfort / nocturia interest (community)", "chronic prostatitis research context (preclinical)", "bph-adjacent talk (community; evidence mostly extract or animal)", "longevity / chromatin-aging interest" ], "summary": "Prostamax is the synthetic four-amino-acid peptide KEDP, a Russian bioregulator discussed for prostate-related symptoms.", "search_blob": "prostamax prostamax prostate bioregulator kedp peptide kedp lys-glu-asp-pro lysyl-glutamyl-aspartyl-proline h-lys-glu-asp-pro-oh prostamax peptide synthetic prostate tetrapeptide khavinson prostate peptide prostamax kedp kedp peptide lys-glu-asp-pro lysyl-glutamyl-aspartyl-proline h-lys-glu-asp-pro-oh men's health discussion prostate support narratives urinary comfort / nocturia interest (community) chronic prostatitis research context (preclinical) bph-adjacent talk (community; evidence mostly extract or animal) longevity / chromatin-aging interest men's health discussion prostate support narratives urinary comfort / nocturia interest (community) chronic prostatitis research context (preclinical) bph-adjacent talk (community; evidence mostly extract or animal) longevity / chromatin-aging interest inflammation and tissue-repair narratives urologic wellness interest (community) libido / sexual-function halo (often stacked or extract-confounded) men's health discussion prostate support narratives urinary comfort / nocturia interest (community) chronic prostatitis research context (preclinical) bph-adjacent talk (community; evidence mostly extract or animal) longevity / chromatin-aging interest prostamax is the synthetic four-amino-acid peptide kedp, a russian bioregulator discussed for prostate-related symptoms. one user described a steadier urine stream and fewer nighttime trips, while also taping their mouth and drinking less overnight. prostamax is the synthetic kedp peptide studied in prostate-related research. some users describe easier flow or fewer nighttime trips; others report no benefit, returning symptoms or worse pain. longevity & bioregulators peptide systemic systemic use is discussed for prostate goals; synthetic kedp, animal-prostate extracts and herbal products are not interchangeable. systemic whole-body circulating", "legal_class": null }, { "id": 106, "slug": "testagen", "name": "Testagen", "aliases": [ "testicular bioregulator", "KEDG peptide", "KEDG", "Lys-Glu-Asp-Gly", "H-Lys-Glu-Asp-Gly-OH", "H-KEDG-OH", "Testagen Cytogen", "Anterior Pituitary Peptide (APP) (vendor label discussions)", "Khavinson testis tetrapeptide", "testis peptide bioregulator" ], "type": "Peptide", "category": "Longevity & bioregulators", "goals_use_cases": [ "hormone axis", "men's health discussion", "hormone axis / HPG support narratives", "age-related low-T talk (community)", "libido (discussed)", "thyroid interest (TSH / T3 / T4 talk)", "testicular / reproductive support narratives", "chronic prostatitis adjunct talk (older writeups)", "longevity / bioregulator courses", "energy & recovery (community)", "fertility-preserving alternative-to-TRT searches", "PCT / post-cycle recovery talk (minority community)", "vs Testoluten / extract sequencing" ], "delivery_methods": [ "oral", "injection discussion" ], "discussion_popularity": "Emerging", "reach": "Mixed", "misspellings_search_terms": [ "testagen", "KEDG peptide", "KEDG", "Lys-Glu-Asp-Gly", "H-Lys-Glu-Asp-Gly-OH", "H-KEDG-OH", "hormone axis / hpg support narratives", "men's health discussion", "age-related low-t talk (community)", "libido (discussed)", "thyroid interest (tsh / t3 / t4 talk)", "testicular / reproductive support narratives" ], "feel_search": [ "hormone axis / hpg support narratives", "men's health discussion", "age-related low-t talk (community)", "libido (discussed)", "thyroid interest (tsh / t3 / t4 talk)", "testicular / reproductive support narratives" ], "summary": "Testagen is the synthetic four-amino-acid peptide KEDG, discussed as a bioregulator for endocrine and testosterone-related interests.", "search_blob": "testagen testagen testicular bioregulator kedg peptide kedg lys-glu-asp-gly h-lys-glu-asp-gly-oh h-kedg-oh testagen cytogen anterior pituitary peptide (app) (vendor label discussions) khavinson testis tetrapeptide testis peptide bioregulator testagen kedg peptide kedg lys-glu-asp-gly h-lys-glu-asp-gly-oh h-kedg-oh hormone axis / hpg support narratives men's health discussion age-related low-t talk (community) libido (discussed) thyroid interest (tsh / t3 / t4 talk) testicular / reproductive support narratives hormone axis men's health discussion hormone axis / hpg support narratives age-related low-t talk (community) libido (discussed) thyroid interest (tsh / t3 / t4 talk) testicular / reproductive support narratives chronic prostatitis adjunct talk (older writeups) longevity / bioregulator courses energy & recovery (community) fertility-preserving alternative-to-trt searches pct / post-cycle recovery talk (minority community) vs testoluten / extract sequencing hormone axis / hpg support narratives men's health discussion age-related low-t talk (community) libido (discussed) thyroid interest (tsh / t3 / t4 talk) testicular / reproductive support narratives testagen is the synthetic four-amino-acid peptide kedg, discussed as a bioregulator for endocrine and testosterone-related interests. one user reported more energy, libido and gym strength while measured testosterone stayed near their previous level and several peptides were co-used. testagen is the synthetic peptide kedg, discussed for libido, energy and natural-testosterone support. reports include feeling better without changed testosterone and no noticeable benefit; stacks and lifestyle changes complicate attribution. longevity & bioregulators peptide mixed mixed \u2014 marketed for reproductive and hormone-related bioregulator effects, with oral or injectable exposure; not a local injury-site agent. mixed local systemic", "legal_class": null }, { "id": 107, "slug": "cerluten", "name": "Cerluten", "aliases": [ "brain bioregulator", "brain peptide complex", "Cerluten\u00ae", "A-5", "Cytomax A-5", "peptide complex A-5", "CNS peptide bioregulator", "nerve cell peptides (marketing)", "Nature\u2019s Marvels CNS / Central Nervous System Bioregulator (related product line)", "Lingual Cerluten (sublingual form discussed)" ], "type": "Peptide", "category": "Longevity & bioregulators", "goals_use_cases": [ "cognition", "longevity", "cognition / memory & attention", "mental capacity maintenance in aging", "neuroprotection (discussed)", "longevity / Khavinson cytomax courses", "post-stroke residual symptoms (historical clinical add-on)", "long-term TBI / craniocerebral injury sequelae (historical clinical add-on)", "vascular encephalopathy support talk", "stress resilience / emotional stability (discussed)", "sleep quality (secondary discussion)", "headache and mental fatigue burden (subjective clinical series)", "healthy aging brain support stacks" ], "delivery_methods": [ "oral", "injection discussion" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "cerluten", "Cerluten\u00ae", "A-5", "Cytomax A-5", "peptide complex A-5", "brain bioregulator", "cognition / memory & attention", "mental capacity maintenance in aging", "neuroprotection (discussed)", "longevity / khavinson cytomax courses", "post-stroke residual symptoms (historical clinical add-on)", "long-term tbi / craniocerebral injury sequelae (historical clinical add-on)" ], "feel_search": [ "cognition / memory & attention", "mental capacity maintenance in aging", "neuroprotection (discussed)", "longevity / khavinson cytomax courses", "post-stroke residual symptoms (historical clinical add-on)", "long-term tbi / craniocerebral injury sequelae (historical clinical add-on)" ], "summary": "Cerluten is an animal cerebral-cortex peptide complex sold mainly in capsules as a brain bioregulator.", "search_blob": "cerluten cerluten brain bioregulator brain peptide complex cerluten\u00ae a-5 cytomax a-5 peptide complex a-5 cns peptide bioregulator nerve cell peptides (marketing) nature\u2019s marvels cns / central nervous system bioregulator (related product line) lingual cerluten (sublingual form discussed) cerluten cerluten\u00ae a-5 cytomax a-5 peptide complex a-5 brain bioregulator cognition / memory & attention mental capacity maintenance in aging neuroprotection (discussed) longevity / khavinson cytomax courses post-stroke residual symptoms (historical clinical add-on) long-term tbi / craniocerebral injury sequelae (historical clinical add-on) cognition longevity cognition / memory & attention mental capacity maintenance in aging neuroprotection (discussed) longevity / khavinson cytomax courses post-stroke residual symptoms (historical clinical add-on) long-term tbi / craniocerebral injury sequelae (historical clinical add-on) vascular encephalopathy support talk stress resilience / emotional stability (discussed) sleep quality (secondary discussion) headache and mental fatigue burden (subjective clinical series) healthy aging brain support stacks cognition / memory & attention mental capacity maintenance in aging neuroprotection (discussed) longevity / khavinson cytomax courses post-stroke residual symptoms (historical clinical add-on) long-term tbi / craniocerebral injury sequelae (historical clinical add-on) cerluten is an animal cerebral-cortex peptide complex sold mainly in capsules as a brain bioregulator. the inspected cognition post lists claimed mechanisms. it does not describe a cerluten course, personal benefit or adverse-effect timeline. cerluten is an animal cerebral-cortex peptide mixture sold mainly in oral capsules. reports include clearer thinking, better sleep or little noticeable change, often with other products; these accounts do not establish brain repair. not a stimulant, not an fda-approved alzheimer\u2019s / stroke / tbi drug, not cortexin itself, not cerebrolysin, not pinealon, not cortagen, not epitalon. longevity & bioregulators peptide systemic mainly oral use; the brain-targeting claim does not establish selective delivery or measured human absorption. systemic whole-body circulating", "legal_class": null }, { "id": 108, "slug": "bronchogen", "name": "Bronchogen", "aliases": [ "respiratory bioregulator", "AEDL peptide", "AEDL", "Ala-Glu-Asp-Leu", "H-Ala-Glu-Asp-Leu-OH / H-AEDL-OH", "ADEL / Ala-Asp-Glu-Leu (letter-order in some peer-reviewed titles)", "peptide AEDL", "bronchial bioregulator", "lung bioregulator (Khavinson tetrapeptide)", "Khavinson bronchial tetrapeptide", "Bronchogen (Cytomax / cytogen capsule discussions)", "bronchial mucosa tetrapeptide" ], "type": "Peptide", "category": "Longevity & bioregulators", "goals_use_cases": [ "respiratory discussion", "immune", "lung & bronchial tissue research interest", "COPD / chronic airway research interest (preclinical framing)", "chronic bronchitis / smoker\u2013pollution narratives", "post-infection / post-viral / post-COVID recovery narratives", "asthma adjunct talk (not a rescue agent)", "immune (local mucosal / sIgA discussion)", "anti-inflammatory discussion (airway / neutrophilic)", "longevity / tissue bioregulation / geroprotection talk", "epithelial repair & mucociliary support (preclinical framing)", "surfactant / alveolar support discussion (preclinical framing)", "pulmonary fibrosis model interest (sparse preclinical)", "performance continuity (breathing comfort talk)", "organ-bioregulator multi-course calendars" ], "delivery_methods": [ "oral", "injection discussion" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "bronchogen", "AEDL", "Ala-Glu-Asp-Leu", "H-Ala-Glu-Asp-Leu-OH / H-AEDL-OH", "ADEL / Ala-Asp-Glu-Leu (letter-order in some peer-reviewed titles)", "peptide AEDL", "respiratory discussion", "lung & bronchial tissue research interest", "copd / chronic airway research interest (preclinical framing)", "chronic bronchitis / smoker\u2013pollution narratives", "post-infection / post-viral / post-covid recovery narratives", "asthma adjunct talk (not a rescue agent)" ], "feel_search": [ "respiratory discussion", "lung & bronchial tissue research interest", "copd / chronic airway research interest (preclinical framing)", "chronic bronchitis / smoker\u2013pollution narratives", "post-infection / post-viral / post-covid recovery narratives", "asthma adjunct talk (not a rescue agent)" ], "summary": "Bronchogen is the synthetic tetrapeptide AEDL, marketed as a lung bioregulator and studied mainly in preclinical respiratory research.", "search_blob": "bronchogen bronchogen respiratory bioregulator aedl peptide aedl ala-glu-asp-leu h-ala-glu-asp-leu-oh / h-aedl-oh adel / ala-asp-glu-leu (letter-order in some peer-reviewed titles) peptide aedl bronchial bioregulator lung bioregulator (khavinson tetrapeptide) khavinson bronchial tetrapeptide bronchogen (cytomax / cytogen capsule discussions) bronchial mucosa tetrapeptide bronchogen aedl ala-glu-asp-leu h-ala-glu-asp-leu-oh / h-aedl-oh adel / ala-asp-glu-leu (letter-order in some peer-reviewed titles) peptide aedl respiratory discussion lung & bronchial tissue research interest copd / chronic airway research interest (preclinical framing) chronic bronchitis / smoker\u2013pollution narratives post-infection / post-viral / post-covid recovery narratives asthma adjunct talk (not a rescue agent) respiratory discussion immune lung & bronchial tissue research interest copd / chronic airway research interest (preclinical framing) chronic bronchitis / smoker\u2013pollution narratives post-infection / post-viral / post-covid recovery narratives asthma adjunct talk (not a rescue agent) immune (local mucosal / siga discussion) anti-inflammatory discussion (airway / neutrophilic) longevity / tissue bioregulation / geroprotection talk epithelial repair & mucociliary support (preclinical framing) surfactant / alveolar support discussion (preclinical framing) pulmonary fibrosis model interest (sparse preclinical) performance continuity (breathing comfort talk) organ-bioregulator multi-course calendars respiratory discussion lung & bronchial tissue research interest copd / chronic airway research interest (preclinical framing) chronic bronchitis / smoker\u2013pollution narratives post-infection / post-viral / post-covid recovery narratives asthma adjunct talk (not a rescue agent) bronchogen is the synthetic tetrapeptide aedl, marketed as a lung bioregulator and studied mainly in preclinical respiratory research. one self-test reports improved peak-flow readings across two courses but did no cardio testing. home spirometry and an uncontrolled design limit the conclusion. bronchogen is a synthetic peptide studied in lung-related research. short 10\u201320 day charts do not establish an active window; reports include easier breathing, uncertain benefit, flushing and heart-rate changes. not a rescue inhaler, steroid substitute, antibiotic/antiviral, mucolytic, oxygen replacement, or proven copd/asthma disease-modifying drug. longevity & bioregulators peptide systemic systemic administration for lung-related goals; selective human lung delivery is not established. systemic whole-body circulating", "legal_class": null }, { "id": 109, "slug": "chonluten", "name": "Chonluten", "aliases": [ "lung bioregulator", "EDG peptide", "Glu-Asp-Gly", "Glutamyl-aspartyl-glycine", "H-Glu-Asp-Gly-OH", "T-34", "T-34 tripeptide", "T34", "bronchial bioregulator", "Honluten", "Khonluten", "Chonluten Cytogen", "Chonluten (Cytomax / bioregulator capsule discussions)", "Khavinson lung peptide", "bronchopulmonary bioregulator" ], "type": "Peptide", "category": "Longevity & bioregulators", "goals_use_cases": [ "respiratory discussion", "lung / bronchial support (discussed)", "COPD / chronic bronchitis adjunct talk", "asthma / bronchial hyperreactivity adjunct talk", "post-viral / post-COVID recovery narratives", "smoking / vaping residual irritation talk", "mucosal / epithelial support (discussed)", "inflammation modulation (preclinical framing)", "longevity / organ-bioregulator calendars", "exercise breathing comfort / aerobic-capacity lore (weak)", "immune modulation (monocyte/macrophage in-vitro framing)", "GI mucosal secondary talk (developer literature)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "chonluten", "EDG peptide", "Glu-Asp-Gly", "Glutamyl-aspartyl-glycine", "H-Glu-Asp-Gly-OH", "T-34", "respiratory discussion", "lung / bronchial support (discussed)", "copd / chronic bronchitis adjunct talk", "asthma / bronchial hyperreactivity adjunct talk", "post-viral / post-covid recovery narratives", "smoking / vaping residual irritation talk" ], "feel_search": [ "respiratory discussion", "lung / bronchial support (discussed)", "copd / chronic bronchitis adjunct talk", "asthma / bronchial hyperreactivity adjunct talk", "post-viral / post-covid recovery narratives", "smoking / vaping residual irritation talk" ], "summary": "Chonluten is the synthetic tripeptide EDG, marketed as a bronchopulmonary bioregulator for lung and breathing concerns.", "search_blob": "chonluten chonluten lung bioregulator edg peptide glu-asp-gly glutamyl-aspartyl-glycine h-glu-asp-gly-oh t-34 t-34 tripeptide t34 bronchial bioregulator honluten khonluten chonluten cytogen chonluten (cytomax / bioregulator capsule discussions) khavinson lung peptide bronchopulmonary bioregulator chonluten edg peptide glu-asp-gly glutamyl-aspartyl-glycine h-glu-asp-gly-oh t-34 respiratory discussion lung / bronchial support (discussed) copd / chronic bronchitis adjunct talk asthma / bronchial hyperreactivity adjunct talk post-viral / post-covid recovery narratives smoking / vaping residual irritation talk respiratory discussion lung / bronchial support (discussed) copd / chronic bronchitis adjunct talk asthma / bronchial hyperreactivity adjunct talk post-viral / post-covid recovery narratives smoking / vaping residual irritation talk mucosal / epithelial support (discussed) inflammation modulation (preclinical framing) longevity / organ-bioregulator calendars exercise breathing comfort / aerobic-capacity lore (weak) immune modulation (monocyte/macrophage in-vitro framing) gi mucosal secondary talk (developer literature) respiratory discussion lung / bronchial support (discussed) copd / chronic bronchitis adjunct talk asthma / bronchial hyperreactivity adjunct talk post-viral / post-covid recovery narratives smoking / vaping residual irritation talk chonluten is the synthetic tripeptide edg, marketed as a bronchopulmonary bioregulator for lung and breathing concerns. a four-week chonluten/bronchogen account describes easier deep breaths and less nighttime coughing, with occasional breathlessness still present. chonluten is the synthetic peptide edg, discussed for breathing comfort. accounts include easier breathing and less coughing in stacks, as well as no detectable change after 1\u20132 courses; these reports do not establish lung repair. longevity & bioregulators peptide systemic whole-body \u2014 people treat this as circulating, not a local pin. systemic whole-body circulating", "legal_class": null }, { "id": 110, "slug": "crystagen", "name": "Crystagen", "aliases": [ "immune bioregulator", "EAD peptide", "EDP peptide", "Glu-Asp-Pro", "EDP tripeptide", "Khavinson immune cytogen", "Crystagen\u00ae (commercial bioregulator branding)", "Kristagen", "T-38 (designation in some originator/vendor lists)", "AC-6 (coded Glu-Asp-Pro in some bioregulator catalogs)", "thymus/immune short peptide bioregulator", "EDG peptide (conflicting vendor sequence claim \u2014 see sequence uncertainty)", "EAD peptide (search misspelling / informal shorthand)", "Glu-Asp-Gly (alternate vendor sequence discussions; often mapped to Chonluten in originator tissue-pair schemes)" ], "type": "Peptide", "category": "Longevity & bioregulators", "goals_use_cases": [ "immune", "immune modulation / immunosenescence (discussed)", "thymus support / thymic epithelial framing (preclinical)", "B-cell and T-cell balance narratives", "longevity / multi-bioregulator calendars", "post-illness or high-load recovery continuity (community)", "seasonal resilience talk", "cellular aging / gene-expression research (originator model)", "post-stress or athletic immune-normalization talk (originator summaries)", "not acute antiviral replacement or infection treatment" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "crystagen", "EDP peptide", "Glu-Asp-Pro", "EDP tripeptide", "immune bioregulator", "Khavinson immune cytogen", "immune modulation / immunosenescence (discussed)", "thymus support / thymic epithelial framing (preclinical)", "b-cell and t-cell balance narratives", "longevity / multi-bioregulator calendars", "post-illness or high-load recovery continuity (community)", "seasonal resilience talk" ], "feel_search": [ "immune modulation / immunosenescence (discussed)", "thymus support / thymic epithelial framing (preclinical)", "b-cell and t-cell balance narratives", "longevity / multi-bioregulator calendars", "post-illness or high-load recovery continuity (community)", "seasonal resilience talk" ], "summary": "Crystagen is the synthetic tripeptide EDP, marketed for immune or thymus support; similarly named products need sequence checks.", "search_blob": "crystagen crystagen immune bioregulator ead peptide edp peptide glu-asp-pro edp tripeptide khavinson immune cytogen crystagen\u00ae (commercial bioregulator branding) kristagen t-38 (designation in some originator/vendor lists) ac-6 (coded glu-asp-pro in some bioregulator catalogs) thymus/immune short peptide bioregulator edg peptide (conflicting vendor sequence claim \u2014 see sequence uncertainty) ead peptide (search misspelling / informal shorthand) glu-asp-gly (alternate vendor sequence discussions; often mapped to chonluten in originator tissue-pair schemes) crystagen edp peptide glu-asp-pro edp tripeptide immune bioregulator khavinson immune cytogen immune modulation / immunosenescence (discussed) thymus support / thymic epithelial framing (preclinical) b-cell and t-cell balance narratives longevity / multi-bioregulator calendars post-illness or high-load recovery continuity (community) seasonal resilience talk immune immune modulation / immunosenescence (discussed) thymus support / thymic epithelial framing (preclinical) b-cell and t-cell balance narratives longevity / multi-bioregulator calendars post-illness or high-load recovery continuity (community) seasonal resilience talk cellular aging / gene-expression research (originator model) post-stress or athletic immune-normalization talk (originator summaries) not acute antiviral replacement or infection treatment immune modulation / immunosenescence (discussed) thymus support / thymic epithelial framing (preclinical) b-cell and t-cell balance narratives longevity / multi-bioregulator calendars post-illness or high-load recovery continuity (community) seasonal resilience talk crystagen is the synthetic tripeptide edp, marketed for immune or thymus support; similarly named products need sequence checks. an enthusiastic long-term peptide user gives no specific immune endpoint. a separate multi-peptide experiment found no significant lymphocyte change at its two-month retest. crystagen is usually identified as the synthetic tripeptide edp. broad positive endorsements coexist with a multi-peptide experiment showing no significant lymphocyte change; neither establishes an isolated crystagen benefit. longevity & bioregulators peptide systemic systemic immune/thymus bioregulator framing; not a local soft-tissue or injury-site injection. systemic whole-body circulating", "legal_class": null }, { "id": 111, "slug": "cortagen", "name": "Cortagen", "aliases": [ "AEDP peptide", "cortex bioregulator", "AEDP", "Ala-Glu-Asp-Pro", "H-Ala-Glu-Asp-Pro-OH", "AEDP tetrapeptide", "Cortagen peptide", "cortex tetrapeptide", "cerebral-cortex tetrapeptide", "Khavinson Cortagen", "Cortexin synthetic analog (AEDP)", "SCHEMBL5491754 (database synonym, vendor listings)" ], "type": "Peptide", "category": "Longevity & bioregulators", "goals_use_cases": [ "cognition", "stress", "cognition / focus baseline (community)", "brain fog / mental stamina (discussed)", "stress load composure (anecdotal)", "neuroprotection interest (preclinical + community)", "peripheral nerve recovery talk (entrapment, post-surgical; animal-driven)", "post-concussion / TBI-adjunct interest (community + extract-era halo)", "longevity / Khavinson bioregulator rotation", "aging-brain support narratives", "on-cycle cortical buffer talk (AAS or heavy stims \u2014 unproven)", "vs Cortexin / Pinealon / Epitalon search adjacency" ], "delivery_methods": [ "injection discussion", "oral" ], "discussion_popularity": "Emerging", "reach": "Mixed", "misspellings_search_terms": [ "cortagen", "AEDP", "Ala-Glu-Asp-Pro", "H-Ala-Glu-Asp-Pro-OH", "AEDP peptide", "AEDP tetrapeptide", "cognition / focus baseline (community)", "brain fog / mental stamina (discussed)", "stress load composure (anecdotal)", "neuroprotection interest (preclinical + community)", "peripheral nerve recovery talk (entrapment, post-surgical; animal-driven)", "post-concussion / tbi-adjunct interest (community + extract-era halo)" ], "feel_search": [ "cognition / focus baseline (community)", "brain fog / mental stamina (discussed)", "stress load composure (anecdotal)", "neuroprotection interest (preclinical + community)", "peripheral nerve recovery talk (entrapment, post-surgical; animal-driven)", "post-concussion / tbi-adjunct interest (community + extract-era halo)" ], "summary": "Cortagen is the synthetic tetrapeptide AEDP, developed from cortex-extract research and marketed as a nervous-system bioregulator.", "search_blob": "cortagen cortagen aedp peptide cortex bioregulator aedp ala-glu-asp-pro h-ala-glu-asp-pro-oh aedp tetrapeptide cortagen peptide cortex tetrapeptide cerebral-cortex tetrapeptide khavinson cortagen cortexin synthetic analog (aedp) schembl5491754 (database synonym, vendor listings) cortagen aedp ala-glu-asp-pro h-ala-glu-asp-pro-oh aedp peptide aedp tetrapeptide cognition / focus baseline (community) brain fog / mental stamina (discussed) stress load composure (anecdotal) neuroprotection interest (preclinical + community) peripheral nerve recovery talk (entrapment, post-surgical; animal-driven) post-concussion / tbi-adjunct interest (community + extract-era halo) cognition stress cognition / focus baseline (community) brain fog / mental stamina (discussed) stress load composure (anecdotal) neuroprotection interest (preclinical + community) peripheral nerve recovery talk (entrapment, post-surgical; animal-driven) post-concussion / tbi-adjunct interest (community + extract-era halo) longevity / khavinson bioregulator rotation aging-brain support narratives on-cycle cortical buffer talk (aas or heavy stims \u2014 unproven) vs cortexin / pinealon / epitalon search adjacency cognition / focus baseline (community) brain fog / mental stamina (discussed) stress load composure (anecdotal) neuroprotection interest (preclinical + community) peripheral nerve recovery talk (entrapment, post-surgical; animal-driven) post-concussion / tbi-adjunct interest (community + extract-era halo) cortagen is the synthetic tetrapeptide aedp, developed from cortex-extract research and marketed as a nervous-system bioregulator. one first-use account describes sleeping all night and half the day. the visible discussion does not supply a later cognitive-benefit result. cortagen is the synthetic aedp peptide discussed for cognition and nerve recovery. reports include clearer thinking, little symptom benefit, unchanged cognition and pronounced sleepiness. longevity & bioregulators peptide mixed mixed \u2014 cortex/cns- and nerve-framed synthetic aedp; community short courses are systemic, not local injury-site dosing or cortexin extract. mixed local systemic", "legal_class": null }, { "id": 112, "slug": "pnc-27", "name": "PNC-27", "aliases": [ "PNC27", "p53-HDM2 related peptide discussion", "PNC 27", "p53-HDM-2 membrane peptide (discussion label)", "chimeric p53-penetratin peptide", "p53 residues 12\u201326 + MRP / penetratin peptide", "OM-301 (Oncolyze lead candidate; previously discussed as PNC-27 lineage)", "HY-P3508 (catalog-style ID on some lab suppliers)" ], "type": "Peptide", "category": "Experimental oncology-adjacent peptides", "goals_use_cases": [ "experimental oncology discussion", "experimental oncology / selective cancer-cell kill discussion", "membrane HDM-2 / MDM2 targeting research", "AML and leukemia stem-cell preclinical interest", "solid-tumor line research (pancreas, breast, ovary, colon, cervix, lung, melanoma, etc.)", "chemo-resistant / cancer-stem-cell ex vivo discussion", "pore-forming (\u201cpoptosis\u201d / membranolysis) mechanism research", "comparison with shorter analog PNC-28 and inactive control PNC-29", "research-only investigational use \u2014 not approved cancer therapy" ], "delivery_methods": [ "research use discussion only" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "pnc-27", "pnc 27", "pnc27", "p53-HDM-2 membrane peptide (discussion label)", "chimeric p53-penetratin peptide", "p53 residues 12\u201326 + MRP / penetratin peptide", "experimental oncology / selective cancer-cell kill discussion", "membrane hdm-2 / mdm2 targeting research", "aml and leukemia stem-cell preclinical interest", "solid-tumor line research (pancreas, breast, ovary, colon, cervix, lung, melanoma, etc.)", "chemo-resistant / cancer-stem-cell ex vivo discussion", "pore-forming (\u201cpoptosis\u201d / membranolysis) mechanism research" ], "feel_search": [ "experimental oncology / selective cancer-cell kill discussion", "membrane hdm-2 / mdm2 targeting research", "aml and leukemia stem-cell preclinical interest", "solid-tumor line research (pancreas, breast, ovary, colon, cervix, lung, melanoma, etc.)", "chemo-resistant / cancer-stem-cell ex vivo discussion", "pore-forming (\u201cpoptosis\u201d / membranolysis) mechanism research" ], "summary": "PNC-27 is a synthetic peptide combining a p53-related segment with a cell-penetrating segment for experimental cancer research.", "search_blob": "pnc-27 pnc-27 pnc27 p53-hdm2 related peptide discussion pnc 27 p53-hdm-2 membrane peptide (discussion label) chimeric p53-penetratin peptide p53 residues 12\u201326 + mrp / penetratin peptide om-301 (oncolyze lead candidate; previously discussed as pnc-27 lineage) hy-p3508 (catalog-style id on some lab suppliers) pnc-27 pnc 27 pnc27 p53-hdm-2 membrane peptide (discussion label) chimeric p53-penetratin peptide p53 residues 12\u201326 + mrp / penetratin peptide experimental oncology / selective cancer-cell kill discussion membrane hdm-2 / mdm2 targeting research aml and leukemia stem-cell preclinical interest solid-tumor line research (pancreas, breast, ovary, colon, cervix, lung, melanoma, etc.) chemo-resistant / cancer-stem-cell ex vivo discussion pore-forming (\u201cpoptosis\u201d / membranolysis) mechanism research experimental oncology discussion experimental oncology / selective cancer-cell kill discussion membrane hdm-2 / mdm2 targeting research aml and leukemia stem-cell preclinical interest solid-tumor line research (pancreas, breast, ovary, colon, cervix, lung, melanoma, etc.) chemo-resistant / cancer-stem-cell ex vivo discussion pore-forming (\u201cpoptosis\u201d / membranolysis) mechanism research comparison with shorter analog pnc-28 and inactive control pnc-29 research-only investigational use \u2014 not approved cancer therapy experimental oncology / selective cancer-cell kill discussion membrane hdm-2 / mdm2 targeting research aml and leukemia stem-cell preclinical interest solid-tumor line research (pancreas, breast, ovary, colon, cervix, lung, melanoma, etc.) chemo-resistant / cancer-stem-cell ex vivo discussion pore-forming (\u201cpoptosis\u201d / membranolysis) mechanism research pnc-27 is a synthetic peptide combining a p53-related segment with a cell-penetrating segment for experimental cancer research. one self-experimenter first mentioned dizziness and fatigue, then said early changes may be unrelated and noticed little after about three weeks. pnc-27 combines p53-derived and membrane-penetrating peptide segments for experimental cancer research. personal accounts include uncertain sensations, no tumor improvement and adverse events; they do not establish human cancer treatment or prevention. experimental oncology-adjacent peptides peptide systemic whole-body exposure is discussed; intratumoral reports focus on local concentration. systemic whole-body circulating", "legal_class": null }, { "id": 113, "slug": "ghrh-1-44", "name": "GHRH (1-44)", "aliases": [ "somatorelin", "growth hormone releasing hormone", "Somatorelin", "Growth hormone\u2013releasing hormone (1-44)", "hGHRH(1-44)", "hGHRH(1-44)NH2", "GHRH-1,44-amide", "GRF (1-44)", "Growth hormone\u2013releasing factor (1-44)", "Somatocrinin (endogenous form discussions)", "GHRH 1-44 amide", "somatotropin releasing hormone (1-44)amide", "Full-length GHRH" ], "type": "Peptide", "category": "Growth hormone axis", "goals_use_cases": [ "muscle growth", "diagnostics adjacency", "anti-aging discussion", "recovery", "body composition (discussed)", "visceral fat (clinical signal)", "sleep (GH-axis adjacency)", "performance", "longevity (discussed)", "IGF-1 support (discussed)", "age-related GH decline discussion" ], "delivery_methods": [ "injection" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "ghrh-1-44", "ghrh 1 44", "ghrh144", "GHRH (1-44)", "ghrh-(1-44)", "Somatorelin", "muscle growth", "diagnostics adjacency", "anti-aging discussion", "recovery", "body composition (discussed)", "visceral fat (clinical signal)" ], "feel_search": [ "muscle growth", "diagnostics adjacency", "anti-aging discussion", "recovery", "body composition (discussed)", "visceral fat (clinical signal)" ], "summary": "GHRH(1-44), or somatorelin, is the full-length hormone that tells the pituitary to release growth hormone; it differs from sermorelin and CJC analogs.", "search_blob": "ghrh (1-44) ghrh-1-44 somatorelin growth hormone releasing hormone somatorelin growth hormone\u2013releasing hormone (1-44) hghrh(1-44) hghrh(1-44)nh2 ghrh-1,44-amide grf (1-44) growth hormone\u2013releasing factor (1-44) somatocrinin (endogenous form discussions) ghrh 1-44 amide somatotropin releasing hormone (1-44)amide full-length ghrh ghrh-1-44 ghrh 1 44 ghrh144 ghrh (1-44) ghrh-(1-44) somatorelin muscle growth diagnostics adjacency anti-aging discussion recovery body composition (discussed) visceral fat (clinical signal) muscle growth diagnostics adjacency anti-aging discussion recovery body composition (discussed) visceral fat (clinical signal) sleep (gh-axis adjacency) performance longevity (discussed) igf-1 support (discussed) age-related gh decline discussion muscle growth diagnostics adjacency anti-aging discussion recovery body composition (discussed) visceral fat (clinical signal) ghrh(1-44), or somatorelin, is the full-length hormone that tells the pituitary to release growth hormone; it differs from sermorelin and cjc analogs. ghrh (1-44), or somatorelin, signals pituitary growth-hormone release. few community logs isolate it from sermorelin, cjc or tesamorelin. growth hormone axis peptide systemic systemic \u2014 binds pituitary ghrh receptors and raises endogenous gh pulses (then igf-1); not a local repair or site-specific fat-dissolve peptide. systemic whole-body circulating", "legal_class": null }, { "id": 114, "slug": "tesamorelin-analogs-discussion", "name": "GHRH analogs (clinic-compounded class discussion)", "aliases": [ "compounded GHRH", "GHRH blends", "Tesamorelin class discussion", "GHRH analogs", "Egrifta (brand reference)", "tesamorelin research discussion", "tesamorelin vs sermorelin vs CJC", "GHRH peptide class", "growth hormone releasing hormone analogs", "clinic GHRH stack talk" ], "type": "Peptide", "category": "Growth hormone axis", "goals_use_cases": [ "fat loss", "recovery", "anti-aging discussion", "visceral fat reduction (discussed)", "trunk / midsection aesthetics", "body composition", "lean mass preservation (discussed)", "liver fat / metabolic talk", "sleep (sermorelin / CJC-ipa adjacency)", "IGF-1 support (discussed)", "performance continuity", "GH-axis alternative to exogenous HGH" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "tesamorelin-analogs-discussion", "tesamorelin analogs discussion", "tesamorelinanalogsdiscussion", "GHRH analogs (clinic-compounded class discussion)", "ghrh-analogs-(clinic-compounded-class-discussion)", "Tesamorelin class discussion", "fat loss", "visceral fat reduction (discussed)", "trunk / midsection aesthetics", "recovery", "anti-aging discussion", "body composition" ], "feel_search": [ "fat loss", "visceral fat reduction (discussed)", "trunk / midsection aesthetics", "recovery", "anti-aging discussion", "body composition" ], "summary": "GHRH analogues are peptides that stimulate pituitary growth-hormone release; this class includes distinct products, not one interchangeable blend.", "search_blob": "ghrh analogs (clinic-compounded class discussion) tesamorelin-analogs-discussion compounded ghrh ghrh blends tesamorelin class discussion ghrh analogs egrifta (brand reference) tesamorelin research discussion tesamorelin vs sermorelin vs cjc ghrh peptide class growth hormone releasing hormone analogs clinic ghrh stack talk tesamorelin-analogs-discussion tesamorelin analogs discussion tesamorelinanalogsdiscussion ghrh analogs (clinic-compounded class discussion) ghrh-analogs-(clinic-compounded-class-discussion) tesamorelin class discussion fat loss visceral fat reduction (discussed) trunk / midsection aesthetics recovery anti-aging discussion body composition fat loss recovery anti-aging discussion visceral fat reduction (discussed) trunk / midsection aesthetics body composition lean mass preservation (discussed) liver fat / metabolic talk sleep (sermorelin / cjc-ipa adjacency) igf-1 support (discussed) performance continuity gh-axis alternative to exogenous hgh fat loss visceral fat reduction (discussed) trunk / midsection aesthetics recovery anti-aging discussion body composition ghrh analogues are peptides that stimulate pituitary growth-hormone release; this class includes distinct products, not one interchangeable blend. tesamorelin users describe mixed waist changes and water retention; the inspected thread does not establish an effect for unnamed analogs. ghrh analogs are a class of peptides that stimulate pituitary growth-hormone release. reports include waist or sleep changes, little benefit, insomnia, swelling and joint aches; the products are not interchangeable. growth hormone axis peptide systemic systemic \u2014 pituitary ghrh-receptor stimulation \u2192 endogenous gh pulses \u2192 hepatic igf-1 and whole-body composition effects. systemic whole-body circulating", "legal_class": null }, { "id": 115, "slug": "selank-tp7-variants", "name": "Selank analogs / TP-7 variants", "aliases": [ "TP7 variants", "selank family", "TP-7", "Selank family", "Selank (TP-7)", "Selanc", "\u0421\u0435\u043b\u0430\u043d\u043a", "Thr-Lys-Pro-Arg-Pro-Gly-Pro family", "TKPRPGP family", "N-Acetyl Selank", "N-Acetyl Selank Amidate", "NA-Selank / NA-Selank Amidate", "Ac-Thr-Lys-Pro-Arg-Pro-Gly-Pro-NH2 (dual-capped form)", "tuftsin + Pro-Gly-Pro heptapeptide family" ], "type": "Peptide", "category": "Cognitive / nootropic peptides", "goals_use_cases": [ "anxiety discussion", "cognition", "anxiety discussion (GAD / generalized anxiety / baseline edge)", "calm focus without heavy sedation", "cognition under stress", "mood smoothing / emotional reactivity", "stress resilience / neurasthenia-style fatigue talk", "social / performance / exam anxiety talk", "nootropic stacks (esp. with Semax family)", "immune-adjacent discussion (tuftsin heritage, secondary)", "sleep balance (discussed; mixed)", "variant hunt: plain vs N-acetyl vs dual-capped amidate stability claims" ], "delivery_methods": [ "nasal" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "selank-tp7-variants", "selank tp7 variants", "selanktp7variants", "Selank analogs / TP-7 variants", "selank-analogs-/-tp-7-variants", "TP-7", "anxiety discussion (gad / generalized anxiety / baseline edge)", "calm focus without heavy sedation", "cognition under stress", "mood smoothing / emotional reactivity", "stress resilience / neurasthenia-style fatigue talk", "social / performance / exam anxiety talk" ], "feel_search": [ "anxiety discussion (gad / generalized anxiety / baseline edge)", "calm focus without heavy sedation", "cognition under stress", "mood smoothing / emotional reactivity", "stress resilience / neurasthenia-style fatigue talk", "social / performance / exam anxiety talk" ], "summary": "This family covers Selank/TP-7-related synthetic peptides discussed for anxiety; altered variants should not inherit the parent peptide's evidence.", "search_blob": "selank analogs / tp-7 variants selank-tp7-variants tp7 variants selank family tp-7 selank family selank (tp-7) selanc \u0441\u0435\u043b\u0430\u043d\u043a thr-lys-pro-arg-pro-gly-pro family tkprpgp family n-acetyl selank n-acetyl selank amidate na-selank / na-selank amidate ac-thr-lys-pro-arg-pro-gly-pro-nh2 (dual-capped form) tuftsin + pro-gly-pro heptapeptide family selank-tp7-variants selank tp7 variants selanktp7variants selank analogs / tp-7 variants selank-analogs-/-tp-7-variants tp-7 anxiety discussion (gad / generalized anxiety / baseline edge) calm focus without heavy sedation cognition under stress mood smoothing / emotional reactivity stress resilience / neurasthenia-style fatigue talk social / performance / exam anxiety talk anxiety discussion cognition anxiety discussion (gad / generalized anxiety / baseline edge) calm focus without heavy sedation cognition under stress mood smoothing / emotional reactivity stress resilience / neurasthenia-style fatigue talk social / performance / exam anxiety talk nootropic stacks (esp. with semax family) immune-adjacent discussion (tuftsin heritage, secondary) sleep balance (discussed; mixed) variant hunt: plain vs n-acetyl vs dual-capped amidate stability claims anxiety discussion (gad / generalized anxiety / baseline edge) calm focus without heavy sedation cognition under stress mood smoothing / emotional reactivity stress resilience / neurasthenia-style fatigue talk social / performance / exam anxiety talk this family covers selank/tp-7-related synthetic peptides discussed for anxiety; altered variants should not inherit the parent peptide's evidence. reports include subtle calm or no benefit, but one n-acetyl selank user described markedly increased anxiety; formulations and co-use differ. selank, or tp-7, and its n-acetyl or amidated variants are discussed for anxiety and calm focus. reports range from a quieter mind to no benefit, detachment or increased anxiety; the modified forms do not share an established effect or dose. cognitive / nootropic peptides peptide systemic systemic cns family \u2014 nasal delivery dominates for whole-brain anxiolytic/nootropic talk, not local tissue repair. systemic whole-body circulating", "legal_class": null }, { "id": 116, "slug": "semax-variants", "name": "Semax family variants", "aliases": [ "Semax analogues", "Met-Semax discussion", "Semax analogs", "N-Acetyl Semax family", "NA-Semax / NASA family", "N-Acetyl Semax Amidate family", "ACTH(4-10) Semax-related peptides", "MEHFPGP variants", "Adamax (Semax-family discussion)", "Semax Amidate", "Ac-MEHFPGP / Ac-MEHFPGP-NH2" ], "type": "Peptide", "category": "Cognitive / nootropic peptides", "goals_use_cases": [ "cognition", "focus", "attention", "working memory (discussed)", "memory / learning support (discussed)", "neuroprotection discussion", "mental performance under stress", "mental stamina / deep-work endurance", "nootropic stacking (especially with Selank-class)", "mood (secondary discussion)", "exam / sprint cognitive support", "ADHD-adjacent focus talk (community only; not an approved indication)", "comparing plain vs capped research-chem forms" ], "delivery_methods": [ "nasal" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "semax-variants", "semax variants", "semaxvariants", "Semax family variants", "semax-family-variants", "Semax analogues", "cognition", "focus", "attention", "working memory (discussed)", "memory / learning support (discussed)", "neuroprotection discussion" ], "feel_search": [ "cognition", "focus", "attention", "working memory (discussed)", "memory / learning support (discussed)", "neuroprotection discussion" ], "summary": "Semax variants are modified ACTH-fragment peptides, including end-capped and adamantane-related versions sold for cognitive interests.", "search_blob": "semax family variants semax-variants semax analogues met-semax discussion semax analogs n-acetyl semax family na-semax / nasa family n-acetyl semax amidate family acth(4-10) semax-related peptides mehfpgp variants adamax (semax-family discussion) semax amidate ac-mehfpgp / ac-mehfpgp-nh2 semax-variants semax variants semaxvariants semax family variants semax-family-variants semax analogues cognition focus attention working memory (discussed) memory / learning support (discussed) neuroprotection discussion cognition focus attention working memory (discussed) memory / learning support (discussed) neuroprotection discussion mental performance under stress mental stamina / deep-work endurance nootropic stacking (especially with selank-class) mood (secondary discussion) exam / sprint cognitive support adhd-adjacent focus talk (community only; not an approved indication) comparing plain vs capped research-chem forms cognition focus attention working memory (discussed) memory / learning support (discussed) neuroprotection discussion semax variants are modified acth-fragment peptides, including end-capped and adamantane-related versions sold for cognitive interests. one n-acetyl-semax-amidate user described subtle focus initially, then little repeat effect when using a larger supplement stack. semax variants are related peptides discussed for cognition. reports include clearer focus, no repeat benefit, brain fog and poor sleep; the forms are not interchangeable. cognitive / nootropic peptides peptide systemic brain-focused semax-family discussion, mainly intranasal; minority subq reports do not establish selective human tissue delivery. systemic whole-body circulating", "legal_class": null }, { "id": 117, "slug": "pt-141-nasal-research", "name": "PT-141 nasal research (bremelanotide routes)", "aliases": [ "PT-141 nasal research", "bremelanotide nasal", "PT-141 nasal spray", "intranasal PT-141", "intranasal bremelanotide", "PT141 nose spray", "PT-141 IN", "bremelanotide intranasal spray", "compounded PT-141 spray", "nasal Vyleesi (misnomer)" ], "type": "Peptide", "category": "Libido & melanocortin", "goals_use_cases": [ "libido", "libido / sexual desire (CNS melanocortin path, discussed)", "historical male ED research (intranasal PT-141 clinical program)", "PDE5 non-responder salvage talk (historical IN trials)", "needle-free delivery interest vs SC autoinjector or vial", "compounded clinic spray access (modern off-label discussion)", "CNS melanocortin (MC3/MC4) desire signaling research", "as-needed desire/arousal window before activity (discussed)", "route-debate: nasal absorption variability vs SC predictability", "stack with PDE5 for desire + erection (historical co-admin + community)" ], "delivery_methods": [ "nasal" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "pt-141-nasal-research", "pt 141 nasal research", "pt141nasalresearch", "PT-141 nasal research (bremelanotide routes)", "pt-141-nasal-research-(bremelanotide-routes)", "PT-141 nasal research", "libido / sexual desire (cns melanocortin path, discussed)", "historical male ed research (intranasal pt-141 clinical program)", "pde5 non-responder salvage talk (historical in trials)", "needle-free delivery interest vs sc autoinjector or vial", "compounded clinic spray access (modern off-label discussion)", "cns melanocortin (mc3/mc4) desire signaling research" ], "feel_search": [ "libido / sexual desire (cns melanocortin path, discussed)", "historical male ed research (intranasal pt-141 clinical program)", "pde5 non-responder salvage talk (historical in trials)", "needle-free delivery interest vs sc autoinjector or vial", "compounded clinic spray access (modern off-label discussion)", "cns melanocortin (mc3/mc4) desire signaling research" ], "summary": "PT-141 nasal research concerns intranasal bremelanotide, a melanocortin-receptor peptide; nasal products differ from the medical injection.", "search_blob": "pt-141 nasal research (bremelanotide routes) pt-141-nasal-research pt-141 nasal research bremelanotide nasal pt-141 nasal spray intranasal pt-141 intranasal bremelanotide pt141 nose spray pt-141 in bremelanotide intranasal spray compounded pt-141 spray nasal vyleesi (misnomer) pt-141-nasal-research pt 141 nasal research pt141nasalresearch pt-141 nasal research (bremelanotide routes) pt-141-nasal-research-(bremelanotide-routes) pt-141 nasal research libido / sexual desire (cns melanocortin path, discussed) historical male ed research (intranasal pt-141 clinical program) pde5 non-responder salvage talk (historical in trials) needle-free delivery interest vs sc autoinjector or vial compounded clinic spray access (modern off-label discussion) cns melanocortin (mc3/mc4) desire signaling research libido libido / sexual desire (cns melanocortin path, discussed) historical male ed research (intranasal pt-141 clinical program) pde5 non-responder salvage talk (historical in trials) needle-free delivery interest vs sc autoinjector or vial compounded clinic spray access (modern off-label discussion) cns melanocortin (mc3/mc4) desire signaling research as-needed desire/arousal window before activity (discussed) route-debate: nasal absorption variability vs sc predictability stack with pde5 for desire + erection (historical co-admin + community) libido / sexual desire (cns melanocortin path, discussed) historical male ed research (intranasal pt-141 clinical program) pde5 non-responder salvage talk (historical in trials) needle-free delivery interest vs sc autoinjector or vial compounded clinic spray access (modern off-label discussion) cns melanocortin (mc3/mc4) desire signaling research pt-141 nasal research concerns intranasal bremelanotide, a melanocortin-receptor peptide; nasal products differ from the medical injection. one nasal user described brief warmth, relaxation and sexual response; replies disputed the amount and reported no effect. pt-141 nasal research concerns bremelanotide delivered as a spray. reports include greater sensitivity or sexual response, no benefit, burning, flushing and nausea; onset and duration vary. libido & melanocortin peptide systemic systemic cns melanocortin (mc3r/mc4r) desire/arousal path \u2014 nasal is a delivery route debate, not a local genital drug. systemic whole-body circulating", "legal_class": null }, { "id": 118, "slug": "afamelanotide-community", "name": "Afamelanotide (community / implant access discussions)", "aliases": [ "Scenesse community talk", "implant MT-1 access discussion", "Afamelanotide implant", "Scenesse", "SCENESSE", "MT-1 implant discussion", "CUV1647", "NDP-MSH (implant context)", "Melanotan I (clinical form)", "afamelanotide 16 mg implant", "[Nle4,D-Phe7]-\u03b1-MSH implant" ], "type": "Peptide", "category": "Tanning & melanocortin", "goals_use_cases": [ "skin/hair", "photoprotection discussion", "tanning / pigmentation (expected implant effect)", "UV tolerance (EPP clinical context)", "access / specialty-drug logistics", "insurance / prior-auth discussion", "aesthetic skin-tone spillover talk (extrapolated, access-limited)", "vitiligo adjunct discussion (investigational implant + NB-UVB)", "other photodermatoses research interest (PMLE, solar urticaria)", "product-identity / counterfeit-vs-licensed implant debates" ], "delivery_methods": [ "implant" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "afamelanotide-community", "afamelanotide community", "afamelanotidecommunity", "Afamelanotide (community / implant access discussions)", "afamelanotide-(community-/-implant-access-discussions)", "Scenesse community talk", "skin/hair", "photoprotection discussion", "tanning / pigmentation (expected implant effect)", "uv tolerance (epp clinical context)", "access / specialty-drug logistics", "insurance / prior-auth discussion" ], "feel_search": [ "skin/hair", "photoprotection discussion", "tanning / pigmentation (expected implant effect)", "uv tolerance (epp clinical context)", "access / specialty-drug logistics", "insurance / prior-auth discussion" ], "summary": "Afamelanotide (Scenesse) is a controlled-release peptide implant used to improve light tolerance in adults with erythropoietic protoporphyria.", "search_blob": "afamelanotide (community / implant access discussions) afamelanotide-community scenesse community talk implant mt-1 access discussion afamelanotide implant scenesse scenesse mt-1 implant discussion cuv1647 ndp-msh (implant context) melanotan i (clinical form) afamelanotide 16 mg implant [nle4,d-phe7]-\u03b1-msh implant afamelanotide-community afamelanotide community afamelanotidecommunity afamelanotide (community / implant access discussions) afamelanotide-(community-/-implant-access-discussions) scenesse community talk skin/hair photoprotection discussion tanning / pigmentation (expected implant effect) uv tolerance (epp clinical context) access / specialty-drug logistics insurance / prior-auth discussion skin/hair photoprotection discussion tanning / pigmentation (expected implant effect) uv tolerance (epp clinical context) access / specialty-drug logistics insurance / prior-auth discussion aesthetic skin-tone spillover talk (extrapolated, access-limited) vitiligo adjunct discussion (investigational implant + nb-uvb) other photodermatoses research interest (pmle, solar urticaria) product-identity / counterfeit-vs-licensed implant debates skin/hair photoprotection discussion tanning / pigmentation (expected implant effect) uv tolerance (epp clinical context) access / specialty-drug logistics insurance / prior-auth discussion afamelanotide (scenesse) is a controlled-release peptide implant used to improve light tolerance in adults with erythropoietic protoporphyria. one epp patient describes a much easier two-hour hike nine days after an implant, but hot fingertips later that night. improved tolerance did not mean no symptoms. scenesse is a clinician-inserted afamelanotide implant for adults with epp, a painful light-sensitivity disorder. patients describe greater outdoor freedom alongside incomplete protection or mixed responses; research melanotan i vials are different products. tanning & melanocortin peptide systemic systemic pigmentation signal; licensed scenesse is a clinician-inserted 16 mg subq implant, not a daily self-injected vial or nasal spray. systemic whole-body circulating", "legal_class": null }, { "id": 119, "slug": "setmelanotide", "name": "Setmelanotide", "aliases": [ "Imcivree", "RM-493", "IMCIVREE", "RM493", "Setmelanotide acetate", "setmelanotide SC" ], "type": "Peptide", "category": "Metabolic / melanocortin", "goals_use_cases": [ "fat loss", "rare obesity pathway discussion", "rare genetic obesity (POMC / PCSK1 / LEPR pathway)", "Bardet\u2013Biedl syndrome obesity / hyperphagia", "acquired hypothalamic obesity (approved / late-stage discussion by region)", "hyperphagia control (pathway-specific)", "appetite regulation via MC4R", "energy expenditure / REE discussion (early human chamber work)", "fat-loss narrative outside genetics (speculative / off-label talk only)", "MC4R pathway research", "comparison point vs GLP-1s and gray-market melanocortins" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "setmelanotide", "Imcivree", "RM-493", "RM493", "Setmelanotide acetate", "setmelanotide SC", "rare genetic obesity (pomc / pcsk1 / lepr pathway)", "bardet\u2013biedl syndrome obesity / hyperphagia", "acquired hypothalamic obesity (approved / late-stage discussion by region)", "hyperphagia control (pathway-specific)", "appetite regulation via mc4r", "energy expenditure / ree discussion (early human chamber work)" ], "feel_search": [ "rare genetic obesity (pomc / pcsk1 / lepr pathway)", "bardet\u2013biedl syndrome obesity / hyperphagia", "acquired hypothalamic obesity (approved / late-stage discussion by region)", "hyperphagia control (pathway-specific)", "appetite regulation via mc4r", "energy expenditure / ree discussion (early human chamber work)" ], "summary": "Setmelanotide is an MC4-receptor agonist peptide used for specified rare and hypothalamic forms of obesity, rather than general obesity.", "search_blob": "setmelanotide setmelanotide imcivree rm-493 imcivree rm493 setmelanotide acetate setmelanotide sc setmelanotide imcivree rm-493 rm493 setmelanotide acetate setmelanotide sc rare genetic obesity (pomc / pcsk1 / lepr pathway) bardet\u2013biedl syndrome obesity / hyperphagia acquired hypothalamic obesity (approved / late-stage discussion by region) hyperphagia control (pathway-specific) appetite regulation via mc4r energy expenditure / ree discussion (early human chamber work) fat loss rare obesity pathway discussion rare genetic obesity (pomc / pcsk1 / lepr pathway) bardet\u2013biedl syndrome obesity / hyperphagia acquired hypothalamic obesity (approved / late-stage discussion by region) hyperphagia control (pathway-specific) appetite regulation via mc4r energy expenditure / ree discussion (early human chamber work) fat-loss narrative outside genetics (speculative / off-label talk only) mc4r pathway research comparison point vs glp-1s and gray-market melanocortins rare genetic obesity (pomc / pcsk1 / lepr pathway) bardet\u2013biedl syndrome obesity / hyperphagia acquired hypothalamic obesity (approved / late-stage discussion by region) hyperphagia control (pathway-specific) appetite regulation via mc4r energy expenditure / ree discussion (early human chamber work) setmelanotide is an mc4-receptor agonist peptide used for specified rare and hypothalamic forms of obesity, rather than general obesity. a caregiver described less persistent food-seeking, alongside early fatigue, headaches and darker skin. setmelanotide is a prescription mc4-receptor agonist for specific obesity conditions. accounts describe less persistent food-seeking alongside nausea, fatigue or pigmentation changes. body-comp claims outside confirmed pathway disease remain speculation; this profile is research/education only, not a use protocol. metabolic / melanocortin peptide systemic systemic mc4r agonist for specific rare obesity indications; hunger-circuit treatment, not local repair or general aesthetic cutting. systemic whole-body circulating", "legal_class": null }, { "id": 120, "slug": "maridebart-cafraglutide", "name": "Maridebart cafraglutide", "aliases": [ "MariTide", "AMG 133 discussion", "AMG 133", "AMG-133", "AMG133", "maridebart cafraglutide", "MariTide (Amgen)", "GIPR antagonist / GLP-1 agonist conjugate", "GIPR-Ab + dual GLP-1 peptide conjugate", "peptide\u2013antibody conjugate obesity candidate", "monthly MariTide (pipeline shorthand)" ], "type": "Peptide", "category": "Metabolic / GLP-1 class", "goals_use_cases": [ "fat loss", "appetite control", "fat loss / chronic weight management (investigational)", "appetite control / satiety (GLP-1 arm)", "weight management with less-frequent injections than weekly incretins", "glycemic control in obesity + type 2 diabetes context", "cardiometabolic risk markers (waist, BP, hs-CRP, select lipids)", "maintenance / durability after large weight loss (Part 2 + Phase 3 framing)", "obesity-related outcomes pipeline interest (ASCVD, HF, OSA \u2014 Phase 3 talk)", "GIP-block vs GIP-agonist mechanism debate (vs tirzepatide)" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "maridebart-cafraglutide", "maridebart cafraglutide", "maridebartcafraglutide", "MariTide", "AMG 133", "AMG-133", "fat loss / chronic weight management (investigational)", "appetite control / satiety (glp-1 arm)", "weight management with less-frequent injections than weekly incretins", "glycemic control in obesity + type 2 diabetes context", "cardiometabolic risk markers (waist, bp, hs-crp, select lipids)", "maintenance / durability after large weight loss (part 2 + phase 3 framing)" ], "feel_search": [ "fat loss / chronic weight management (investigational)", "appetite control / satiety (glp-1 arm)", "weight management with less-frequent injections than weekly incretins", "glycemic control in obesity + type 2 diabetes context", "cardiometabolic risk markers (waist, bp, hs-crp, select lipids)", "maintenance / durability after large weight loss (part 2 + phase 3 framing)" ], "summary": "Maridebart cafraglutide (MariTide) is an investigational antibody\u2013peptide obesity treatment that activates GLP-1 receptors and blocks GIP receptors.", "search_blob": "maridebart cafraglutide maridebart-cafraglutide maritide amg 133 discussion amg 133 amg-133 amg133 maridebart cafraglutide maritide (amgen) gipr antagonist / glp-1 agonist conjugate gipr-ab + dual glp-1 peptide conjugate peptide\u2013antibody conjugate obesity candidate monthly maritide (pipeline shorthand) maridebart-cafraglutide maridebart cafraglutide maridebartcafraglutide maritide amg 133 amg-133 fat loss / chronic weight management (investigational) appetite control / satiety (glp-1 arm) weight management with less-frequent injections than weekly incretins glycemic control in obesity + type 2 diabetes context cardiometabolic risk markers (waist, bp, hs-crp, select lipids) maintenance / durability after large weight loss (part 2 + phase 3 framing) fat loss appetite control fat loss / chronic weight management (investigational) appetite control / satiety (glp-1 arm) weight management with less-frequent injections than weekly incretins glycemic control in obesity + type 2 diabetes context cardiometabolic risk markers (waist, bp, hs-crp, select lipids) maintenance / durability after large weight loss (part 2 + phase 3 framing) obesity-related outcomes pipeline interest (ascvd, hf, osa \u2014 phase 3 talk) gip-block vs gip-agonist mechanism debate (vs tirzepatide) fat loss / chronic weight management (investigational) appetite control / satiety (glp-1 arm) weight management with less-frequent injections than weekly incretins glycemic control in obesity + type 2 diabetes context cardiometabolic risk markers (waist, bp, hs-crp, select lipids) maintenance / durability after large weight loss (part 2 + phase 3 framing) maridebart cafraglutide (maritide) is an investigational antibody\u2013peptide obesity treatment that activates glp-1 receptors and blocks gip receptors. reduced appetite or weight can come with nausea, vomiting or constipation. early gi effects matter even with a monthly schedule; one claimed trial participant described persistent constipation. maridebart cafraglutide is an investigational antibody-peptide conjugate studied for weight management. claimed participants describe quieter cravings and weight loss alongside constipation, vomiting, fatigue or little noticeable change; assignments remain unverified. metabolic / glp-1 class peptide systemic systemic \u2014 a subcutaneous peptide\u2013antibody conjugate studied for appetite, weight, glycemic and cardiometabolic effects. systemic whole-body circulating", "legal_class": null }, { "id": 121, "slug": "vk2735", "name": "VK2735", "aliases": [ "Viking GLP-1/GIP discussion", "Viking VK2735", "VK-2735", "VKTX dual agonist", "Viking GLP-1/GIP dual agonist", "VENTURE VK2735", "VANQUISH VK2735", "Oral VK2735 / VK2735 tablet" ], "type": "Peptide", "category": "Metabolic / GLP-1 class", "goals_use_cases": [ "fat loss", "metabolic health", "fat loss / obesity weight management (primary clinical program)", "appetite regulation / food-noise reduction (class dual-agonist talk)", "metabolic / cardiometabolic risk-factor improvement (trial context)", "obesity with type 2 diabetes (VANQUISH-2 Phase 3 arm)", "oral incretin access without a different molecule than the injectable", "weight maintenance after induction (monthly SC / low-dose oral research)", "needle-averse or needle-fatigue dual-agonist interest", "pipeline comparison vs tirzepatide / retatrutide / oral GLP-1s", "performance continuity after large weight change (discussion only)", "research-chemical curiosity after Phase 2 headlines (sparse verified logs)" ], "delivery_methods": [ "subcutaneous", "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "vk2735", "Viking VK2735", "VK-2735", "VKTX dual agonist", "Viking GLP-1/GIP dual agonist", "VENTURE VK2735", "fat loss / obesity weight management (primary clinical program)", "appetite regulation / food-noise reduction (class dual-agonist talk)", "metabolic / cardiometabolic risk-factor improvement (trial context)", "obesity with type 2 diabetes (vanquish-2 phase 3 arm)", "oral incretin access without a different molecule than the injectable", "weight maintenance after induction (monthly sc / low-dose oral research)" ], "feel_search": [ "fat loss / obesity weight management (primary clinical program)", "appetite regulation / food-noise reduction (class dual-agonist talk)", "metabolic / cardiometabolic risk-factor improvement (trial context)", "obesity with type 2 diabetes (vanquish-2 phase 3 arm)", "oral incretin access without a different molecule than the injectable", "weight maintenance after induction (monthly sc / low-dose oral research)" ], "summary": "VK2735 is an investigational GLP-1/GIP receptor agonist peptide developed in injectable and oral formulations for weight management.", "search_blob": "vk2735 vk2735 viking glp-1/gip discussion viking vk2735 vk-2735 vktx dual agonist viking glp-1/gip dual agonist venture vk2735 vanquish vk2735 oral vk2735 / vk2735 tablet vk2735 viking vk2735 vk-2735 vktx dual agonist viking glp-1/gip dual agonist venture vk2735 fat loss / obesity weight management (primary clinical program) appetite regulation / food-noise reduction (class dual-agonist talk) metabolic / cardiometabolic risk-factor improvement (trial context) obesity with type 2 diabetes (vanquish-2 phase 3 arm) oral incretin access without a different molecule than the injectable weight maintenance after induction (monthly sc / low-dose oral research) fat loss metabolic health fat loss / obesity weight management (primary clinical program) appetite regulation / food-noise reduction (class dual-agonist talk) metabolic / cardiometabolic risk-factor improvement (trial context) obesity with type 2 diabetes (vanquish-2 phase 3 arm) oral incretin access without a different molecule than the injectable weight maintenance after induction (monthly sc / low-dose oral research) needle-averse or needle-fatigue dual-agonist interest pipeline comparison vs tirzepatide / retatrutide / oral glp-1s performance continuity after large weight change (discussion only) research-chemical curiosity after phase 2 headlines (sparse verified logs) fat loss / obesity weight management (primary clinical program) appetite regulation / food-noise reduction (class dual-agonist talk) metabolic / cardiometabolic risk-factor improvement (trial context) obesity with type 2 diabetes (vanquish-2 phase 3 arm) oral incretin access without a different molecule than the injectable weight maintenance after induction (monthly sc / low-dose oral research) vk2735 is an investigational glp-1/gip receptor agonist peptide developed in injectable and oral formulations for weight management. trial participants reported nausea and vomiting, usually mild or moderate; oral and injectable formulations had different study settings. vk2735 is an experimental glp-1/gip peptide developed as injections and tablets for weight management. trial participants describe less food craving and weight loss alongside plateaus, fatigue and difficult side effects; blinded accounts cannot identify their assigned treatment. metabolic / glp-1 class peptide systemic systemic \u2014 dual glp-1/gip agonist developed as weekly subq and daily oral formulations for whole-body metabolic effects. systemic whole-body circulating", "legal_class": null }, { "id": 122, "slug": "eccn-agonist-class", "name": "Dual/triple agonist research class (non-reta)", "aliases": [ "multi-agonist peptides", "glucagon/GIP/GLP-1 class talk", "dual GLP-1/GIP agonists", "dual GLP-1/glucagon agonists", "triple agonist class (excluding retatrutide)", "incretin multi-agonists", "next-gen metabolic agonists", "dual/triple G agonists", "GIP/GLP-1 dual class", "GCG/GLP-1 dual class", "oxyntomodulin-analog duals", "multi-receptor incretin peptides" ], "type": "Peptide", "category": "Metabolic / GLP-1 class", "goals_use_cases": [ "fat loss", "metabolic health", "fat loss / chronic weight management", "appetite control / food-noise reduction", "glycemic control (T2D trial context)", "liver fat / MASLD discussion", "MASH / fibrosis research interest", "body composition (fat vs lean share discussion)", "obesity research (pipeline comparisons)", "cardiometabolic markers (waist, BP, lipids, liver enzymes)", "energy-expenditure narratives (glucagon arm)", "step-up after mono-GLP-1 plateau (community switch talk)", "visceral / organ fat reduction (imaging substudies)" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "eccn-agonist-class", "eccn agonist class", "eccnagonistclass", "Dual/triple agonist research class (non-reta)", "dual/triple-agonist-research-class-(non-reta)", "multi-agonist peptides", "fat loss / chronic weight management", "metabolic health", "appetite control / food-noise reduction", "glycemic control (t2d trial context)", "liver fat / masld discussion", "mash / fibrosis research interest" ], "feel_search": [ "fat loss / chronic weight management", "metabolic health", "appetite control / food-noise reduction", "glycemic control (t2d trial context)", "liver fat / masld discussion", "mash / fibrosis research interest" ], "summary": "This class groups dual and triple receptor peptides combining GLP-1 with GIP and/or glucagon activity for metabolic and weight-management research.", "search_blob": "dual/triple agonist research class (non-reta) eccn-agonist-class multi-agonist peptides glucagon/gip/glp-1 class talk dual glp-1/gip agonists dual glp-1/glucagon agonists triple agonist class (excluding retatrutide) incretin multi-agonists next-gen metabolic agonists dual/triple g agonists gip/glp-1 dual class gcg/glp-1 dual class oxyntomodulin-analog duals multi-receptor incretin peptides eccn-agonist-class eccn agonist class eccnagonistclass dual/triple agonist research class (non-reta) dual/triple-agonist-research-class-(non-reta) multi-agonist peptides fat loss / chronic weight management metabolic health appetite control / food-noise reduction glycemic control (t2d trial context) liver fat / masld discussion mash / fibrosis research interest fat loss metabolic health fat loss / chronic weight management appetite control / food-noise reduction glycemic control (t2d trial context) liver fat / masld discussion mash / fibrosis research interest body composition (fat vs lean share discussion) obesity research (pipeline comparisons) cardiometabolic markers (waist, bp, lipids, liver enzymes) energy-expenditure narratives (glucagon arm) step-up after mono-glp-1 plateau (community switch talk) visceral / organ fat reduction (imaging substudies) fat loss / chronic weight management metabolic health appetite control / food-noise reduction glycemic control (t2d trial context) liver fat / masld discussion mash / fibrosis research interest this class groups dual and triple receptor peptides combining glp-1 with gip and/or glucagon activity for metabolic and weight-management research. survodutide participants in one thread describe very different appetite and nausea patterns, including symptoms after increases. those reports are specific to that drug and trial. this class groups distinct metabolic peptides. appetite, weight and stomach-symptom reports vary by drug; liver-fat findings come from specific studies. metabolic / glp-1 class peptide systemic systemic multi-receptor metabolic peptides acting on appetite, glycemia, energy expenditure and hepatic fat; not local injury injects. systemic whole-body circulating", "legal_class": null }, { "id": 123, "slug": "5-amino-1mq-analogs", "name": "NNMT inhibitor class (beyond 5-Amino-1MQ)", "aliases": [ "NNMT inhibitors", "1MQ analogs", "5-Amino-1MQ analogs", "NNMTi class", "JBSNF-000088", "6-methoxynicotinamide", "JBSNF-000028", "JBSNF-000265", "MQ-scaffold NNMT inhibitors", "7-amino-1MQ", "2,3-diamino-1MQ", "1-methylquinolinium analogs", "nicotinamide N-methyltransferase inhibitors", "NAM-competitive NNMT inhibitors", "tricyclic NNMT inhibitors (Sanofi series)" ], "type": "Non-peptide", "category": "Metabolic research compounds", "goals_use_cases": [ "fat loss", "metabolic health", "body recomposition", "insulin sensitivity research (preclinical)", "NAD+ / methylation pathway discussion", "obesity research tools", "visceral adipose / white-fat NNMT narratives", "GLP-1 stack adjunct (community, mostly via parent compound)", "next-gen / alternate NNMTi curiosity after 5-Amino-1MQ hype", "muscle function / aged-muscle talk (parent scaffold; preclinical)", "diet-switch synergy narratives (preclinical NNMTi class)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "5-amino-1mq-analogs", "5 amino 1mq analogs", "5amino1mqanalogs", "NNMT inhibitor class (beyond 5-Amino-1MQ)", "nnmt-inhibitor-class-(beyond-5-amino-1mq)", "NNMT inhibitors", "fat loss", "metabolic health", "body recomposition", "insulin sensitivity research (preclinical)", "nad+ / methylation pathway discussion", "obesity research tools" ], "feel_search": [ "fat loss", "metabolic health", "body recomposition", "insulin sensitivity research (preclinical)", "nad+ / methylation pathway discussion", "obesity research tools" ], "summary": "NNMT inhibitors are a research class beyond 5-Amino-1MQ, studied for metabolic effects; different molecules are not interchangeable.", "search_blob": "nnmt inhibitor class (beyond 5-amino-1mq) 5-amino-1mq-analogs nnmt inhibitors 1mq analogs 5-amino-1mq analogs nnmti class jbsnf-000088 6-methoxynicotinamide jbsnf-000028 jbsnf-000265 mq-scaffold nnmt inhibitors 7-amino-1mq 2,3-diamino-1mq 1-methylquinolinium analogs nicotinamide n-methyltransferase inhibitors nam-competitive nnmt inhibitors tricyclic nnmt inhibitors (sanofi series) 5-amino-1mq-analogs 5 amino 1mq analogs 5amino1mqanalogs nnmt inhibitor class (beyond 5-amino-1mq) nnmt-inhibitor-class-(beyond-5-amino-1mq) nnmt inhibitors fat loss metabolic health body recomposition insulin sensitivity research (preclinical) nad+ / methylation pathway discussion obesity research tools fat loss metabolic health body recomposition insulin sensitivity research (preclinical) nad+ / methylation pathway discussion obesity research tools visceral adipose / white-fat nnmt narratives glp-1 stack adjunct (community, mostly via parent compound) next-gen / alternate nnmti curiosity after 5-amino-1mq hype muscle function / aged-muscle talk (parent scaffold; preclinical) diet-switch synergy narratives (preclinical nnmti class) fat loss metabolic health body recomposition insulin sensitivity research (preclinical) nad+ / methylation pathway discussion obesity research tools nnmt inhibitors are a research class beyond 5-amino-1mq, studied for metabolic effects; different molecules are not interchangeable. the available user log concerns parent 5-amino-1mq. it does not establish the feel, onset or duration of the other nnmt inhibitors. nnmt inhibitors beyond 5-amino-1mq are a research class of small molecules studied for metabolic effects. human accounts here concern the parent compound and do not establish an alternate inhibitor's benefits, onset or adverse-effect profile. metabolic research compounds non-peptide systemic systemic \u2014 whole-body nnmt block aimed at adipose/liver nad salvage and sam/1-mna flux; oral small molecules dominate both papers and community talk. systemic whole-body circulating", "legal_class": null }, { "id": 124, "slug": "slu-pp-class", "name": "ERR agonist class (SLU-PP family)", "aliases": [ "ERR agonists", "exercise mimetic discussion class", "SLU-PP-332", "SLU-PP-915", "SLU-PP class", "SLU PP class", "ERR pan-agonists", "pan-ERR agonists", "Saint Louis University PP series", "Burris lab ERR agonists" ], "type": "Non-peptide", "category": "Metabolic research compounds", "goals_use_cases": [ "endurance", "fat loss", "metabolic health", "endurance / aerobic capacity (preclinical + community)", "fat loss / body recomposition (discussed)", "metabolic health / energy expenditure", "mitochondrial / oxidative capacity (discussed)", "insulin sensitivity / glucose markers (preclinical)", "exercise-mimetic research framing", "performance continuity without more volume (discussed)", "oral vs injectable metabolic research-chem culture", "heart-failure / cardiac metabolic research (preclinical, disease models)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "slu-pp-class", "slu pp class", "sluppclass", "ERR agonist class (SLU-PP family)", "err-agonist-class-(slu-pp-family)", "SLU-PP-332", "endurance / aerobic capacity (preclinical + community)", "fat loss / body recomposition (discussed)", "metabolic health / energy expenditure", "mitochondrial / oxidative capacity (discussed)", "insulin sensitivity / glucose markers (preclinical)", "exercise-mimetic research framing" ], "feel_search": [ "endurance / aerobic capacity (preclinical + community)", "fat loss / body recomposition (discussed)", "metabolic health / energy expenditure", "mitochondrial / oxidative capacity (discussed)", "insulin sensitivity / glucose markers (preclinical)", "exercise-mimetic research framing" ], "summary": "The SLU-PP family contains experimental small-molecule estrogen-related-receptor agonists, discussed for metabolism and endurance.", "search_blob": "err agonist class (slu-pp family) slu-pp-class err agonists exercise mimetic discussion class slu-pp-332 slu-pp-915 slu-pp class slu pp class err pan-agonists pan-err agonists saint louis university pp series burris lab err agonists slu-pp-class slu pp class sluppclass err agonist class (slu-pp family) err-agonist-class-(slu-pp-family) slu-pp-332 endurance / aerobic capacity (preclinical + community) fat loss / body recomposition (discussed) metabolic health / energy expenditure mitochondrial / oxidative capacity (discussed) insulin sensitivity / glucose markers (preclinical) exercise-mimetic research framing endurance fat loss metabolic health endurance / aerobic capacity (preclinical + community) fat loss / body recomposition (discussed) metabolic health / energy expenditure mitochondrial / oxidative capacity (discussed) insulin sensitivity / glucose markers (preclinical) exercise-mimetic research framing performance continuity without more volume (discussed) oral vs injectable metabolic research-chem culture heart-failure / cardiac metabolic research (preclinical, disease models) endurance / aerobic capacity (preclinical + community) fat loss / body recomposition (discussed) metabolic health / energy expenditure mitochondrial / oxidative capacity (discussed) insulin sensitivity / glucose markers (preclinical) exercise-mimetic research framing the slu-pp family contains experimental small-molecule estrogen-related-receptor agonists, discussed for metabolism and endurance. slu-pp-915 posters describe better endurance alongside fatigue or slower recovery; those reports cannot describe every slu-pp compound. slu-pp-332 and slu-pp-915 are different experimental small molecules discussed for metabolism and endurance. reports include easier cardio, no benefit, fatigue and poor sleep; their compounds, routes and amounts cannot be treated as interchangeable. metabolic research compounds non-peptide systemic systemic \u2014 small-molecule pan-err agonists studied for body-wide aerobic gene programs, energy use and exercise adaptation. systemic whole-body circulating", "legal_class": null }, { "id": 125, "slug": "ss-20", "name": "SS-20", "aliases": [ "Szeto-Schiller peptides adjacency", "SBT-20", "SBT-020", "SBT20", "SBT 20", "Phe-D-Arg-Phe-Lys-NH2", "H-Phe-D-Arg-Phe-Lys-NH2", "Szeto-Schiller peptide SS-20", "Szeto-Schiller peptide 20", "SS20", "SS 20" ], "type": "Peptide", "category": "Mitochondrial & metabolic peptides", "goals_use_cases": [ "aging", "mitochondrial discussion", "longevity", "mitochondrial discussion (class / analog to SS-31)", "longevity / bioenergetics interest (minority, mostly by adjacency)", "cellular energy / ATP support (discussed, preclinical-heavy)", "neuroprotection research (MPTP / dopaminergic models)", "oxidative stress and mtROS reduction (model-dependent)", "ischemia-reperfusion / cardioprotection research", "chronic kidney / renal mitochondrial research", "Huntington\u2019s disease investigational program (SBT-020)", "performance continuity (weak minority talk, usually SS-31 bleed)", "cardiolipin / IMM structure talk without Dmt scavenging" ], "delivery_methods": [ "research injection discussion" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "ss-20", "ss 20", "ss20", "SBT-20", "SBT-020", "SBT20", "mitochondrial discussion (class / analog to ss-31)", "longevity / bioenergetics interest (minority, mostly by adjacency)", "cellular energy / atp support (discussed, preclinical-heavy)", "neuroprotection research (mptp / dopaminergic models)", "oxidative stress and mtros reduction (model-dependent)", "ischemia-reperfusion / cardioprotection research" ], "feel_search": [ "mitochondrial discussion (class / analog to ss-31)", "longevity / bioenergetics interest (minority, mostly by adjacency)", "cellular energy / atp support (discussed, preclinical-heavy)", "neuroprotection research (mptp / dopaminergic models)", "oxidative stress and mtros reduction (model-dependent)", "ischemia-reperfusion / cardioprotection research" ], "summary": "SS-20 is a synthetic four-amino-acid Szeto\u2013Schiller peptide studied for mitochondrial biology; it is distinct from SS-31.", "search_blob": "ss-20 ss-20 szeto-schiller peptides adjacency sbt-20 sbt-020 sbt20 sbt 20 phe-d-arg-phe-lys-nh2 h-phe-d-arg-phe-lys-nh2 szeto-schiller peptide ss-20 szeto-schiller peptide 20 ss20 ss 20 ss-20 ss 20 ss20 sbt-20 sbt-020 sbt20 mitochondrial discussion (class / analog to ss-31) longevity / bioenergetics interest (minority, mostly by adjacency) cellular energy / atp support (discussed, preclinical-heavy) neuroprotection research (mptp / dopaminergic models) oxidative stress and mtros reduction (model-dependent) ischemia-reperfusion / cardioprotection research aging mitochondrial discussion longevity mitochondrial discussion (class / analog to ss-31) longevity / bioenergetics interest (minority, mostly by adjacency) cellular energy / atp support (discussed, preclinical-heavy) neuroprotection research (mptp / dopaminergic models) oxidative stress and mtros reduction (model-dependent) ischemia-reperfusion / cardioprotection research chronic kidney / renal mitochondrial research huntington\u2019s disease investigational program (sbt-020) performance continuity (weak minority talk, usually ss-31 bleed) cardiolipin / imm structure talk without dmt scavenging mitochondrial discussion (class / analog to ss-31) longevity / bioenergetics interest (minority, mostly by adjacency) cellular energy / atp support (discussed, preclinical-heavy) neuroprotection research (mptp / dopaminergic models) oxidative stress and mtros reduction (model-dependent) ischemia-reperfusion / cardioprotection research ss-20 is a synthetic four-amino-acid szeto\u2013schiller peptide studied for mitochondrial biology; it is distinct from ss-31. the inspected forum discusses related ss peptides and laboratory claims, rather than a direct ss-20 user experience. ss-20 is a mitochondrial research peptide distinct from ss-31. direct user reports are sparse, and its small human study found no overall functional benefit. not ss-31/elamipretide/forzinity, not mots-c/humanin (mitochondrial-derived peptides), not an approved longevity or consumer drug, not a stimulant. mitochondrial & metabolic peptides peptide systemic systemic with preferential concentration at the inner mitochondrial membrane after parenteral exposure; far less community volume than ss-31/elamipretide. systemic whole-body circulating", "legal_class": null }, { "id": 126, "slug": "humanin-analogs", "name": "Humanin analogs (HNG etc.)", "aliases": [ "HNG", "S14G-humanin", "S14G-HN", "Humanin-G", "HN-S14G", "sHNG", "HNGF6A", "HNG-F6A", "colivelin", "AGA-(C8R)HNG17", "HN analogs", "synthetic humanin derivatives", "humanin analogues", "MAPRGFSCLLLLTGEIDLPVKRRA (HNG sequence)" ], "type": "Peptide", "category": "Mitochondrial & metabolic peptides", "goals_use_cases": [ "longevity", "neuroprotection discussion", "longevity / healthspan", "cognitive aging / AD research interest", "mitochondrial function / cytoprotection", "metabolic health", "insulin sensitivity (discussed)", "cardiovascular / ischemia research interest", "beta-cell survival / diabetes models", "healthy aging / healthspan", "anti-apoptotic cell-stress resilience", "chemotherapy-toxicity protection research (preclinical)", "stroke / MCAO model interest (preclinical)", "male germ-cell protection models (preclinical)" ], "delivery_methods": [ "research routes" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "humanin-analogs", "humanin analogs", "humaninanalogs", "Humanin analogs (HNG etc.)", "humanin-analogs-(hng-etc.)", "HNG", "longevity / healthspan", "neuroprotection discussion", "cognitive aging / ad research interest", "mitochondrial function / cytoprotection", "metabolic health", "insulin sensitivity (discussed)" ], "feel_search": [ "longevity / healthspan", "neuroprotection discussion", "cognitive aging / ad research interest", "mitochondrial function / cytoprotection", "metabolic health", "insulin sensitivity (discussed)" ], "summary": "Humanin analogs are modified versions such as HNG/S14G-humanin, studied mainly in cells and animals for stress protection and aging-related biology.", "search_blob": "humanin analogs (hng etc.) humanin-analogs hng s14g-humanin s14g-hn humanin-g hn-s14g shng hngf6a hng-f6a colivelin aga-(c8r)hng17 hn analogs synthetic humanin derivatives humanin analogues maprgfsclllltgeidlpvkrra (hng sequence) humanin-analogs humanin analogs humaninanalogs humanin analogs (hng etc.) humanin-analogs-(hng-etc.) hng longevity / healthspan neuroprotection discussion cognitive aging / ad research interest mitochondrial function / cytoprotection metabolic health insulin sensitivity (discussed) longevity neuroprotection discussion longevity / healthspan cognitive aging / ad research interest mitochondrial function / cytoprotection metabolic health insulin sensitivity (discussed) cardiovascular / ischemia research interest beta-cell survival / diabetes models healthy aging / healthspan anti-apoptotic cell-stress resilience chemotherapy-toxicity protection research (preclinical) stroke / mcao model interest (preclinical) male germ-cell protection models (preclinical) longevity / healthspan neuroprotection discussion cognitive aging / ad research interest mitochondrial function / cytoprotection metabolic health insulin sensitivity (discussed) humanin analogs are modified versions such as hng/s14g-humanin, studied mainly in cells and animals for stress protection and aging-related biology. humanin analogs are modified peptides studied mainly in cells and animals for cell survival. human reports describe possible sleep or calm changes, no perceptible benefit and adverse swelling, often without verified molecule identity. mitochondrial & metabolic peptides peptide systemic systemic \u2014 studied for circulating cell-survival and metabolic signals across several organs; selective human tissue delivery is not established. systemic whole-body circulating", "legal_class": null }, { "id": 127, "slug": "shlp-class", "name": "SHLPs (small humanin-like peptides)", "aliases": [ "SHLP2", "SHLP6", "mitochondrial-derived peptides", "SHLP1\u20136", "SHLP1", "SHLP3", "SHLP4", "SHLP5", "small humanin-like peptides", "small humanin-like peptide 2", "mitochondrial-derived peptides SHLP", "MT-RNR2 SHLPs", "16S rRNA SHLPs", "K4R-SHLP2", "K4R SHLP2", "m.2158T>C SHLP2 variant" ], "type": "Peptide", "category": "Mitochondrial & metabolic peptides", "goals_use_cases": [ "longevity", "metabolic health", "longevity / healthspan discussion", "metabolic health / insulin sensitivity research", "mitochondrial function / OCR\u2013ATP modulation", "neuroprotection discussion (SHLP2)", "cytoprotection research (SHLP2/3)", "Parkinson\u2019s disease research interest (SHLP2 / K4R)", "age-related macular degeneration (AMD) cell models (SHLP2)", "islet amyloid / T2D mechanism research (SHLP2 + HNG)", "obesity / energy homeostasis models (SHLP2)", "apoptosis / oncology research interest (SHLP6)", "healthy aging / circulating-MDP decline narrative", "MDP multi-agent stack footnotes (humanin + MOTS-c + SHLP2)" ], "delivery_methods": [ "research" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "shlp-class", "shlp class", "shlpclass", "SHLPs (small humanin-like peptides)", "shlps-(small-humanin-like-peptides)", "SHLP1\u20136", "longevity / healthspan discussion", "metabolic health / insulin sensitivity research", "mitochondrial function / ocr\u2013atp modulation", "neuroprotection discussion (shlp2)", "cytoprotection research (shlp2/3)", "parkinson\u2019s disease research interest (shlp2 / k4r)" ], "feel_search": [ "longevity / healthspan discussion", "metabolic health / insulin sensitivity research", "mitochondrial function / ocr\u2013atp modulation", "neuroprotection discussion (shlp2)", "cytoprotection research (shlp2/3)", "parkinson\u2019s disease research interest (shlp2 / k4r)" ], "summary": "SHLP1\u20136 are small humanin-like peptides encoded in mitochondrial DNA, studied for cellular stress, metabolism and aging-related biology.", "search_blob": "shlps (small humanin-like peptides) shlp-class shlp2 shlp6 mitochondrial-derived peptides shlp1\u20136 shlp1 shlp3 shlp4 shlp5 small humanin-like peptides small humanin-like peptide 2 mitochondrial-derived peptides shlp mt-rnr2 shlps 16s rrna shlps k4r-shlp2 k4r shlp2 m.2158t>c shlp2 variant shlp-class shlp class shlpclass shlps (small humanin-like peptides) shlps-(small-humanin-like-peptides) shlp1\u20136 longevity / healthspan discussion metabolic health / insulin sensitivity research mitochondrial function / ocr\u2013atp modulation neuroprotection discussion (shlp2) cytoprotection research (shlp2/3) parkinson\u2019s disease research interest (shlp2 / k4r) longevity metabolic health longevity / healthspan discussion metabolic health / insulin sensitivity research mitochondrial function / ocr\u2013atp modulation neuroprotection discussion (shlp2) cytoprotection research (shlp2/3) parkinson\u2019s disease research interest (shlp2 / k4r) age-related macular degeneration (amd) cell models (shlp2) islet amyloid / t2d mechanism research (shlp2 + hng) obesity / energy homeostasis models (shlp2) apoptosis / oncology research interest (shlp6) healthy aging / circulating-mdp decline narrative mdp multi-agent stack footnotes (humanin + mots-c + shlp2) longevity / healthspan discussion metabolic health / insulin sensitivity research mitochondrial function / ocr\u2013atp modulation neuroprotection discussion (shlp2) cytoprotection research (shlp2/3) parkinson\u2019s disease research interest (shlp2 / k4r) shlp1\u20136 are small humanin-like peptides encoded in mitochondrial dna, studied for cellular stress, metabolism and aging-related biology. shlps are six small humanin-like peptides discussed for metabolism and aging. their experimental effects differ; sparse experience notes describe subtle energy or recovery alongside no obvious change, without establishing a typical human response. mitochondrial & metabolic peptides peptide systemic systemic class \u2014 circulating mitochondrial-derived signals encoded in mtdna 16s rrna (mt-rnr2), same genomic neighborhood as humanin. systemic whole-body circulating", "legal_class": null }, { "id": 128, "slug": "apigenin", "name": "Apigenin", "aliases": [ "CD38 discussion flavonoid", "4',5,7-trihydroxyflavone", "Apigenin flavonoid", "Chamomile flavonoid (dietary context)", "5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one", "Huberman sleep-stack apigenin (community shorthand)", "Apigenine (common misspelling/EU labeling)", "C15H10O5 flavone" ], "type": "Non-peptide", "category": "Longevity & cellular energy", "goals_use_cases": [ "longevity", "sleep adjacency", "NAD discussion", "CD38 / NAD salvage interest", "anxiety / calm (discussed)", "inflammation (discussed)", "antioxidant / polyphenol stack interest", "healthy aging / healthspan", "senomorphic / SASP quieting interest (preclinical talk)", "GABA-A / wind-down support (community)", "NMN/NR stack companion", "Huberman-style nightly sleep cocktail", "mood / GAD-adjacent chamomile pathway (extract literature)", "metabolic / glucose-lipid animal-model interest", "muscle / physical-capacity adjacency (mouse N+A and standalone lore)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "apigenin", "4',5,7-trihydroxyflavone", "CD38 discussion flavonoid", "Apigenin flavonoid", "Chamomile flavonoid (dietary context)", "5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one", "longevity", "sleep adjacency", "nad discussion", "cd38 / nad salvage interest", "anxiety / calm (discussed)", "inflammation (discussed)" ], "feel_search": [ "longevity", "sleep adjacency", "nad discussion", "cd38 / nad salvage interest", "anxiety / calm (discussed)", "inflammation (discussed)" ], "summary": "Apigenin is a plant flavone found in chamomile and other foods, sold as a supplement for sleep and relaxation.", "search_blob": "apigenin apigenin cd38 discussion flavonoid 4',5,7-trihydroxyflavone apigenin flavonoid chamomile flavonoid (dietary context) 5,7-dihydroxy-2-(4-hydroxyphenyl)-4h-1-benzopyran-4-one huberman sleep-stack apigenin (community shorthand) apigenine (common misspelling/eu labeling) c15h10o5 flavone apigenin 4',5,7-trihydroxyflavone cd38 discussion flavonoid apigenin flavonoid chamomile flavonoid (dietary context) 5,7-dihydroxy-2-(4-hydroxyphenyl)-4h-1-benzopyran-4-one longevity sleep adjacency nad discussion cd38 / nad salvage interest anxiety / calm (discussed) inflammation (discussed) longevity sleep adjacency nad discussion cd38 / nad salvage interest anxiety / calm (discussed) inflammation (discussed) antioxidant / polyphenol stack interest healthy aging / healthspan senomorphic / sasp quieting interest (preclinical talk) gaba-a / wind-down support (community) nmn/nr stack companion huberman-style nightly sleep cocktail mood / gad-adjacent chamomile pathway (extract literature) metabolic / glucose-lipid animal-model interest muscle / physical-capacity adjacency (mouse n+a and standalone lore) longevity sleep adjacency nad discussion cd38 / nad salvage interest anxiety / calm (discussed) inflammation (discussed) apigenin is a plant flavone found in chamomile and other foods, sold as a supplement for sleep and relaxation. one commenter reports calmer mood; another sleeps more continuously with magnesium co-use. others report little effect, brief benefit that fades, irritability, night waking or next-day fog. apigenin is a plant flavone discussed for sleep and nad-related mechanisms. reports include calm, stimulation, morning fog and no benefit, often with other supplements. longevity & cellular energy non-peptide systemic systemic \u2014 oral plant flavone discussed in calm, sleep and nad/cd38 stacks; not a local injectate or topical research peptide. systemic whole-body circulating", "legal_class": null }, { "id": 129, "slug": "pqq", "name": "PQQ", "aliases": [ "Pyrroloquinoline quinone", "PQQ disodium salt", "Pyrroloquinoline quinone disodium", "PQQ\u00b7Na2", "Methoxatin (chemical synonym in literature)", "BioPQQ (Mitsubishi branded fermented form)", "mnemoPQQ (Ryusendo branded form in some Japanese trials)", "PureQQ (Nascent chemically synthesized form)", "MGCPQQ (EU novel-food branded form discussed)" ], "type": "Non-peptide", "category": "Longevity & cellular energy", "goals_use_cases": [ "mitochondrial discussion", "cognition", "energy", "mitochondrial discussion / biogenesis talk", "cognition / memory / attention (healthy adults)", "energy / subjective fatigue reduction", "longevity / healthy-aging stacks", "sleep quality (open-label discussion)", "mood / stress (discussed)", "antioxidant / redox-cycling discussion", "inflammation markers (CRP/IL-6 talk)", "LDL / lipid discussion (small trial)", "exercise + mito-marker stacks (not clear ergogen)", "performance support (discussed; weak single-agent proof)", "CoQ10 companion in mitochondrial formulas" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "pqq", "Pyrroloquinoline quinone", "PQQ disodium salt", "Pyrroloquinoline quinone disodium", "PQQ\u00b7Na2", "Methoxatin (chemical synonym in literature)", "mitochondrial discussion / biogenesis talk", "cognition / memory / attention (healthy adults)", "energy / subjective fatigue reduction", "longevity / healthy-aging stacks", "sleep quality (open-label discussion)", "mood / stress (discussed)" ], "feel_search": [ "mitochondrial discussion / biogenesis talk", "cognition / memory / attention (healthy adults)", "energy / subjective fatigue reduction", "longevity / healthy-aging stacks", "sleep quality (open-label discussion)", "mood / stress (discussed)" ], "summary": "PQQ is a redox-active small molecule, commonly sold as an oral disodium-salt supplement for mitochondrial and energy-related interests.", "search_blob": "pqq pqq pyrroloquinoline quinone pqq disodium salt pyrroloquinoline quinone disodium pqq\u00b7na2 methoxatin (chemical synonym in literature) biopqq (mitsubishi branded fermented form) mnemopqq (ryusendo branded form in some japanese trials) pureqq (nascent chemically synthesized form) mgcpqq (eu novel-food branded form discussed) pqq pyrroloquinoline quinone pqq disodium salt pyrroloquinoline quinone disodium pqq\u00b7na2 methoxatin (chemical synonym in literature) mitochondrial discussion / biogenesis talk cognition / memory / attention (healthy adults) energy / subjective fatigue reduction longevity / healthy-aging stacks sleep quality (open-label discussion) mood / stress (discussed) mitochondrial discussion cognition energy mitochondrial discussion / biogenesis talk cognition / memory / attention (healthy adults) energy / subjective fatigue reduction longevity / healthy-aging stacks sleep quality (open-label discussion) mood / stress (discussed) antioxidant / redox-cycling discussion inflammation markers (crp/il-6 talk) ldl / lipid discussion (small trial) exercise + mito-marker stacks (not clear ergogen) performance support (discussed; weak single-agent proof) coq10 companion in mitochondrial formulas mitochondrial discussion / biogenesis talk cognition / memory / attention (healthy adults) energy / subjective fatigue reduction longevity / healthy-aging stacks sleep quality (open-label discussion) mood / stress (discussed) pqq is a redox-active small molecule, commonly sold as an oral disodium-salt supplement for mitochondrial and energy-related interests. the thread includes feeling warmer, no change after 90 days, and different responses in people reporting mitochondrial problems. pqq is an oral redox-active supplement discussed for energy and cognition. reports include alertness, no benefit, stimulation, sleepiness, disrupted sleep and adverse mood changes, often with other supplements. longevity & cellular energy non-peptide systemic systemic \u2014 an oral redox-active supplement discussed for cellular energy and mitochondrial signaling. this does not establish selective tissue delivery, mitochondrial rebuilding or a uniform stimulating effect. systemic whole-body circulating", "legal_class": null }, { "id": 130, "slug": "coq10", "name": "CoQ10 / Ubiquinol", "aliases": [ "ubiquinone", "ubiquinol", "Coenzyme Q10", "ubidecarenone", "CoQ-10", "coenzyme Q-10", "CoQH2 / CoQ10H2 (reduced form nomenclature)", "Kaneka Ubiquinol (branded reduced form often cited)", "Bio-Quinone / Myoqinon (trial/soft-gel ubiquinone brands discussed)" ], "type": "Non-peptide", "category": "Longevity & cellular energy", "goals_use_cases": [ "mitochondrial discussion", "cardiovascular discussion", "energy", "cardiovascular / heart-failure adjunct discussion", "energy / fatigue (subjective)", "longevity / healthy aging", "statin-related muscle comfort (discussed; evidence mixed)", "antioxidant / membrane redox support (discussed)", "blood-pressure support (discussed)", "migraine prevention (nutraceutical stack talk)", "male fertility / sperm quality narratives", "exercise recovery / \u201cmito stack\u201d performance talk", "neurodegeneration high-dose research lore (Parkinson/Huntington trial culture)", "comparison of ubiquinone vs ubiquinol forms" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "coq10", "CoQ10 / Ubiquinol", "coq10-/-ubiquinol", "Coenzyme Q10", "ubiquinone", "ubiquinol", "mitochondrial discussion", "cardiovascular / heart-failure adjunct discussion", "energy / fatigue (subjective)", "longevity / healthy aging", "statin-related muscle comfort (discussed; evidence mixed)", "antioxidant / membrane redox support (discussed)" ], "feel_search": [ "mitochondrial discussion", "cardiovascular / heart-failure adjunct discussion", "energy / fatigue (subjective)", "longevity / healthy aging", "statin-related muscle comfort (discussed; evidence mixed)", "antioxidant / membrane redox support (discussed)" ], "summary": "CoQ10 is a normal cell-energy cofactor sold as ubiquinone or ubiquinol supplements, discussed for energy, migraine and cardiovascular interests.", "search_blob": "coq10 / ubiquinol coq10 ubiquinone ubiquinol coenzyme q10 ubidecarenone coq-10 coenzyme q-10 coqh2 / coq10h2 (reduced form nomenclature) kaneka ubiquinol (branded reduced form often cited) bio-quinone / myoqinon (trial/soft-gel ubiquinone brands discussed) coq10 coq10 / ubiquinol coq10-/-ubiquinol coenzyme q10 ubiquinone ubiquinol mitochondrial discussion cardiovascular / heart-failure adjunct discussion energy / fatigue (subjective) longevity / healthy aging statin-related muscle comfort (discussed; evidence mixed) antioxidant / membrane redox support (discussed) mitochondrial discussion cardiovascular discussion energy cardiovascular / heart-failure adjunct discussion energy / fatigue (subjective) longevity / healthy aging statin-related muscle comfort (discussed; evidence mixed) antioxidant / membrane redox support (discussed) blood-pressure support (discussed) migraine prevention (nutraceutical stack talk) male fertility / sperm quality narratives exercise recovery / \u201cmito stack\u201d performance talk neurodegeneration high-dose research lore (parkinson/huntington trial culture) comparison of ubiquinone vs ubiquinol forms mitochondrial discussion cardiovascular / heart-failure adjunct discussion energy / fatigue (subjective) longevity / healthy aging statin-related muscle comfort (discussed; evidence mixed) antioxidant / membrane redox support (discussed) coq10 is a normal cell-energy cofactor sold as ubiquinone or ubiquinol supplements, discussed for energy, migraine and cardiovascular interests. sleep reports point in opposite directions: one ubiquinol user sleeps better without extra daytime energy; another coq10 user feels energized but develops worse insomnia. coq10 is a cellular energy cofactor sold orally as ubiquinone or ubiquinol. reports include better energy or sleep, no noticeable change, and insomnia or lethargy; formulation and other supplements complicate comparisons. longevity & cellular energy non-peptide systemic systemic oral fat-soluble cofactor aimed at circulating and tissue coq pools; not a local injectable peptide or acute stimulant. systemic whole-body circulating", "legal_class": null }, { "id": 131, "slug": "alpha-lipoic-acid", "name": "Alpha-Lipoic Acid (ALA)", "aliases": [ "R-ALA", "thioctic acid", "ALA", "\u03b1-Lipoic acid", "alpha lipoic acid", "Thioctic acid", "R-lipoic acid", "R-(+)-lipoic acid", "S-lipoic acid", "R,S-lipoic acid (racemic)", "d,l-lipoic acid", "Na-RALA (sodium R-lipoate)", "sodium R-lipoate", "Dihydrolipoic acid (DHLA / reduced form)", "thioctic acid (EU/clinical synonym)" ], "type": "Non-peptide", "category": "Antioxidant & metabolic adjacents", "goals_use_cases": [ "metabolic health", "neuropathy discussion", "antioxidant discussion", "diabetic peripheral neuropathy symptom discussion", "burning / tingling / paresthesia threads (diabetic and idiopathic)", "metabolic health / insulin sensitivity talk", "glucose / HbA1c adjacency", "antioxidant / redox / oxidative-stress stacks", "mitochondrial cofactor / mito-support framing", "bodybuilding nutrient-partitioning / carb-meal timing (R-ALA / Na-RALA lore)", "weight management adjacency (modest meta signals)", "ALCAR + ALA neuropathy / mito duo", "liver / detox / heavy-metal chelation narratives (mostly preclinical/community)", "skin / cosmeceutical antioxidant adjacency (minority)", "cardiac autonomic neuropathy (CAN) discussion (narrow trial talk)", "MS / neuroinflammation research adjacency (high-dose oral pilots)", "chemotherapy-induced neuropathy adjacency (mixed/debated)" ], "delivery_methods": [ "oral", "IV" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "alpha-lipoic-acid", "alpha lipoic acid", "alphalipoicacid", "Alpha-Lipoic Acid (ALA)", "alpha-lipoic-acid-(ala)", "ALA", "diabetic peripheral neuropathy symptom discussion", "burning / tingling / paresthesia threads (diabetic and idiopathic)", "metabolic health / insulin sensitivity talk", "glucose / hba1c adjacency", "antioxidant / redox / oxidative-stress stacks", "mitochondrial cofactor / mito-support framing" ], "feel_search": [ "diabetic peripheral neuropathy symptom discussion", "burning / tingling / paresthesia threads (diabetic and idiopathic)", "metabolic health / insulin sensitivity talk", "glucose / hba1c adjacency", "antioxidant / redox / oxidative-stress stacks", "mitochondrial cofactor / mito-support framing" ], "summary": "ALA is a non-peptide supplement discussed for nerve symptoms and metabolic goals. Reports range from relief within hours or weeks to no benefit, stomach symptoms or unwanted\u2026", "search_blob": "alpha-lipoic acid (ala) alpha-lipoic-acid r-ala thioctic acid ala \u03b1-lipoic acid alpha lipoic acid thioctic acid r-lipoic acid r-(+)-lipoic acid s-lipoic acid r,s-lipoic acid (racemic) d,l-lipoic acid na-rala (sodium r-lipoate) sodium r-lipoate dihydrolipoic acid (dhla / reduced form) thioctic acid (eu/clinical synonym) alpha-lipoic-acid alpha lipoic acid alphalipoicacid alpha-lipoic acid (ala) alpha-lipoic-acid-(ala) ala diabetic peripheral neuropathy symptom discussion burning / tingling / paresthesia threads (diabetic and idiopathic) metabolic health / insulin sensitivity talk glucose / hba1c adjacency antioxidant / redox / oxidative-stress stacks mitochondrial cofactor / mito-support framing metabolic health neuropathy discussion antioxidant discussion diabetic peripheral neuropathy symptom discussion burning / tingling / paresthesia threads (diabetic and idiopathic) metabolic health / insulin sensitivity talk glucose / hba1c adjacency antioxidant / redox / oxidative-stress stacks mitochondrial cofactor / mito-support framing bodybuilding nutrient-partitioning / carb-meal timing (r-ala / na-rala lore) weight management adjacency (modest meta signals) alcar + ala neuropathy / mito duo liver / detox / heavy-metal chelation narratives (mostly preclinical/community) skin / cosmeceutical antioxidant adjacency (minority) cardiac autonomic neuropathy (can) discussion (narrow trial talk) ms / neuroinflammation research adjacency (high-dose oral pilots) chemotherapy-induced neuropathy adjacency (mixed/debated) diabetic peripheral neuropathy symptom discussion burning / tingling / paresthesia threads (diabetic and idiopathic) metabolic health / insulin sensitivity talk glucose / hba1c adjacency antioxidant / redox / oxidative-stress stacks mitochondrial cofactor / mito-support framing ala is a non-peptide supplement discussed for nerve symptoms and metabolic goals. reports range from relief within hours or weeks to no benefit, stomach symptoms or unwanted\u2026 neuropathy reports range from relief within hours to a subtle change noticed only after stopping. several accounts combine ala with benfotiamine, obscuring attribution. ala is a non-peptide supplement discussed for nerve symptoms and metabolic goals. reports range from relief within hours or weeks to no benefit, stomach symptoms or unwanted stimulation. antioxidant & metabolic adjacents non-peptide systemic systemic \u2014 oral (consumer/research) and clinical iv antioxidant and mitochondrial cofactor with whole-body metabolic and neuropathy talk. systemic whole-body circulating", "legal_class": null }, { "id": 132, "slug": "taurine", "name": "Taurine", "aliases": [ "L-taurine", "2-aminoethanesulfonic acid", "tauric acid (historical name in some older texts)", "2-aminoethane-1-sulfonic acid", "Tau (abbreviation in papers)" ], "type": "Non-peptide", "category": "Longevity & performance staples", "goals_use_cases": [ "longevity", "performance", "metabolic health", "longevity / healthspan (post-2023 animal papers)", "performance / exercise capacity", "pre-workout ergogenic interest", "metabolic health (glucose, lipids, inflammation markers)", "cardiovascular / blood-pressure discussion", "heart-failure research interest (clinical literature)", "recovery / DOMS talk", "muscle cramp stacks (with electrolytes)", "cellular stress / osmoregulation narratives", "sleep / calm (minority)", "vegan / low-meat dietary gap talk", "energy-drink ingredient literacy" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "taurine", "L-taurine", "2-aminoethanesulfonic acid", "tauric acid (historical name in some older texts)", "2-aminoethane-1-sulfonic acid", "Tau (abbreviation in papers)", "longevity / healthspan (post-2023 animal papers)", "performance / exercise capacity", "pre-workout ergogenic interest", "metabolic health (glucose, lipids, inflammation markers)", "cardiovascular / blood-pressure discussion", "heart-failure research interest (clinical literature)" ], "feel_search": [ "longevity / healthspan (post-2023 animal papers)", "performance / exercise capacity", "pre-workout ergogenic interest", "metabolic health (glucose, lipids, inflammation markers)", "cardiovascular / blood-pressure discussion", "heart-failure research interest (clinical literature)" ], "summary": "Taurine is a sulfur-containing amino sulfonic acid made by the body and found in animal foods, supplements and many energy drinks.", "search_blob": "taurine taurine l-taurine 2-aminoethanesulfonic acid tauric acid (historical name in some older texts) 2-aminoethane-1-sulfonic acid tau (abbreviation in papers) taurine l-taurine 2-aminoethanesulfonic acid tauric acid (historical name in some older texts) 2-aminoethane-1-sulfonic acid tau (abbreviation in papers) longevity / healthspan (post-2023 animal papers) performance / exercise capacity pre-workout ergogenic interest metabolic health (glucose, lipids, inflammation markers) cardiovascular / blood-pressure discussion heart-failure research interest (clinical literature) longevity performance metabolic health longevity / healthspan (post-2023 animal papers) performance / exercise capacity pre-workout ergogenic interest metabolic health (glucose, lipids, inflammation markers) cardiovascular / blood-pressure discussion heart-failure research interest (clinical literature) recovery / doms talk muscle cramp stacks (with electrolytes) cellular stress / osmoregulation narratives sleep / calm (minority) vegan / low-meat dietary gap talk energy-drink ingredient literacy longevity / healthspan (post-2023 animal papers) performance / exercise capacity pre-workout ergogenic interest metabolic health (glucose, lipids, inflammation markers) cardiovascular / blood-pressure discussion heart-failure research interest (clinical literature) taurine is a sulfur-containing amino sulfonic acid made by the body and found in animal foods, supplements and many energy drinks. accounts range from calm and less rumination to next-day drowsiness, headache or feeling wired and anxious. taurine is a sulfur-containing compound discussed for calm, training and longevity. reports include calm or easier recovery, no effect, next-day drowsiness, feeling wired and both relief and worsening of cramps. longevity & performance staples non-peptide systemic systemic \u2014 a free amino sulfonic acid discussed for muscle, heart, brain and bile-acid functions; not a site-specific injection. systemic whole-body circulating", "legal_class": null }, { "id": 133, "slug": "glycine", "name": "Glycine", "aliases": [ "glycinate adjacency", "collagen amino acid", "Gly", "L-glycine", "aminoacetic acid", "2-aminoacetic acid", "glycinate adjacency (Mg glycinate / bisglycinate salts \u2014 not gram-equivalent free glycine)", "GlyNAC (glycine + NAC stack name)", "free-form glycine powder", "glycine monohydrate (bulk powder form shorthand)" ], "type": "Non-peptide", "category": "Sleep & longevity staples", "goals_use_cases": [ "sleep", "longevity", "recovery", "sleep quality / onset / next-day refresh", "sleep restriction recovery / less daytime fatigue after short nights", "longevity / methionine-restriction-mimetic talk", "collagen / connective tissue support (discussed)", "joint, tendon, skin adjacency (discussed)", "glutathione / antioxidant support (GlyNAC and solo GSH-precursor talk)", "recovery / training-adjacent soft-tissue talk", "evening wind-down / mild calm (not knockout sedation)", "metabolic / insulin-sensitivity interest (mixed; population caveats)", "schizophrenia negative-symptom adjunct research context (high-dose clinical only)", "creatine / purine / one-carbon metabolism adjacency", "Huberman-adjacent intermittent sleep-stack add-on talk" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "glycine", "Gly", "L-glycine", "aminoacetic acid", "2-aminoacetic acid", "glycinate adjacency (Mg glycinate / bisglycinate salts \u2014 not gram-equivalent free glycine)", "sleep quality / onset / next-day refresh", "sleep restriction recovery / less daytime fatigue after short nights", "longevity / methionine-restriction-mimetic talk", "collagen / connective tissue support (discussed)", "joint, tendon, skin adjacency (discussed)", "glutathione / antioxidant support (glynac and solo gsh-precursor talk)" ], "feel_search": [ "sleep quality / onset / next-day refresh", "sleep restriction recovery / less daytime fatigue after short nights", "longevity / methionine-restriction-mimetic talk", "collagen / connective tissue support (discussed)", "joint, tendon, skin adjacency (discussed)", "glutathione / antioxidant support (glynac and solo gsh-precursor talk)" ], "summary": "Glycine is an amino acid taken as powder or capsules; biohackers mainly discuss sleep quality, next-day alertness and GlyNAC combinations.", "search_blob": "glycine glycine glycinate adjacency collagen amino acid gly l-glycine aminoacetic acid 2-aminoacetic acid glycinate adjacency (mg glycinate / bisglycinate salts \u2014 not gram-equivalent free glycine) glynac (glycine + nac stack name) free-form glycine powder glycine monohydrate (bulk powder form shorthand) glycine gly l-glycine aminoacetic acid 2-aminoacetic acid glycinate adjacency (mg glycinate / bisglycinate salts \u2014 not gram-equivalent free glycine) sleep quality / onset / next-day refresh sleep restriction recovery / less daytime fatigue after short nights longevity / methionine-restriction-mimetic talk collagen / connective tissue support (discussed) joint, tendon, skin adjacency (discussed) glutathione / antioxidant support (glynac and solo gsh-precursor talk) sleep longevity recovery sleep quality / onset / next-day refresh sleep restriction recovery / less daytime fatigue after short nights longevity / methionine-restriction-mimetic talk collagen / connective tissue support (discussed) joint, tendon, skin adjacency (discussed) glutathione / antioxidant support (glynac and solo gsh-precursor talk) recovery / training-adjacent soft-tissue talk evening wind-down / mild calm (not knockout sedation) metabolic / insulin-sensitivity interest (mixed; population caveats) schizophrenia negative-symptom adjunct research context (high-dose clinical only) creatine / purine / one-carbon metabolism adjacency huberman-adjacent intermittent sleep-stack add-on talk sleep quality / onset / next-day refresh sleep restriction recovery / less daytime fatigue after short nights longevity / methionine-restriction-mimetic talk collagen / connective tissue support (discussed) joint, tendon, skin adjacency (discussed) glutathione / antioxidant support (glynac and solo gsh-precursor talk) glycine is an amino acid taken as powder or capsules; biohackers mainly discuss sleep quality, next-day alertness and glynac combinations. glycine is an amino acid taken as oral powder or capsules. sleep reports include easier wind-down and clearer mornings, but also no improvement, repeated waking or unwanted next-day mellowness. sleep & longevity staples non-peptide systemic systemic \u2014 oral free amino acid; sleep thermoregulation, collagen substrate, and glutathione-precursor goals are framed whole-body, not site-injected. systemic whole-body circulating", "legal_class": null }, { "id": 134, "slug": "tongkat-ali", "name": "Tongkat Ali", "aliases": [ "Eurycoma longifolia", "LJ100", "Eurycoma longifolia Jack", "Physta", "Longjack", "Long Jack", "Pasak Bumi", "Malaysian ginseng (informal marketplace label)", "Tongkat", "TA (forum shorthand)" ], "type": "Non-peptide", "category": "Herbals in hormone discourse", "goals_use_cases": [ "libido", "hormone axis", "stress", "stress / cortisol balance (discussed)", "testosterone support (discussed)", "sexual function", "mood / vitality (discussed)", "male fertility / semen parameters (discussed)", "fatigue / AMS scores (discussed)", "performance continuity", "aging male wellness (discussed)", "free testosterone talk (community)", "women's libido/stress crossover (discussed)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "tongkat-ali", "tongkat ali", "tongkatali", "Eurycoma longifolia", "Eurycoma longifolia Jack", "LJ100", "libido", "hormone axis", "stress / cortisol balance (discussed)", "testosterone support (discussed)", "sexual function", "mood / vitality (discussed)" ], "feel_search": [ "libido", "hormone axis", "stress / cortisol balance (discussed)", "testosterone support (discussed)", "sexual function", "mood / vitality (discussed)" ], "summary": "Tongkat Ali is the root herb Eurycoma longifolia, commonly sold as standardized extracts for libido and hormone-related interests.", "search_blob": "tongkat ali tongkat-ali eurycoma longifolia lj100 eurycoma longifolia jack physta longjack long jack pasak bumi malaysian ginseng (informal marketplace label) tongkat ta (forum shorthand) tongkat-ali tongkat ali tongkatali eurycoma longifolia eurycoma longifolia jack lj100 libido hormone axis stress / cortisol balance (discussed) testosterone support (discussed) sexual function mood / vitality (discussed) libido hormone axis stress stress / cortisol balance (discussed) testosterone support (discussed) sexual function mood / vitality (discussed) male fertility / semen parameters (discussed) fatigue / ams scores (discussed) performance continuity aging male wellness (discussed) free testosterone talk (community) women's libido/stress crossover (discussed) libido hormone axis stress / cortisol balance (discussed) testosterone support (discussed) sexual function mood / vitality (discussed) tongkat ali is the root herb eurycoma longifolia, commonly sold as standardized extracts for libido and hormone-related interests. one long-term user described an energizing effect followed by marked brain fog; other supplements and wellbutrin complicated attribution. tongkat ali is an oral root extract discussed for libido and energy. reports include improvement, no change, stomach upset, insomnia and delayed brain fog. herbals in hormone discourse non-peptide systemic systemic oral root extract\u2014hpg axis, stress-hormone, and whole-body vitality pathways, not a single local target. systemic whole-body circulating", "legal_class": null }, { "id": 135, "slug": "fadogia-agrestis", "name": "Fadogia agrestis", "aliases": [ "Fadogia", "Black aphrodisiac", "Baakin gagai", "Fadogia agrestis stem extract", "Fadogia agrestis (Schweinf. Ex Hiern)", "Fadogia agrestis (Rubiaceae)", "Nigerian fadogia (marketplace shorthand)", "FA (forum shorthand)", "Fadogia + Tongkat stack (combo product context)" ], "type": "Non-peptide", "category": "Herbals in hormone discourse", "goals_use_cases": [ "libido", "hormone axis", "sexual function (discussed)", "free testosterone (discussed)", "total testosterone (discussed)", "luteinizing hormone (LH) support (discussed)", "performance continuity", "male vitality (discussed)", "morning wood / drive (community)", "natural T stack companion to tongkat (discussed)", "athletic recovery / training mood (discussed)", "anti-TRT bridge or TRT-avoidance self-experiment (discussed)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "fadogia-agrestis", "fadogia agrestis", "fadogiaagrestis", "Fadogia", "Black aphrodisiac", "Baakin gagai", "libido", "hormone axis", "sexual function (discussed)", "free testosterone (discussed)", "total testosterone (discussed)", "luteinizing hormone (lh) support (discussed)" ], "feel_search": [ "libido", "hormone axis", "sexual function (discussed)", "free testosterone (discussed)", "total testosterone (discussed)", "luteinizing hormone (lh) support (discussed)" ], "summary": "Fadogia agrestis is a shrub sold as an oral plant extract for libido and testosterone-related interest; human evidence remains limited.", "search_blob": "fadogia agrestis fadogia-agrestis fadogia black aphrodisiac baakin gagai fadogia agrestis stem extract fadogia agrestis (schweinf. ex hiern) fadogia agrestis (rubiaceae) nigerian fadogia (marketplace shorthand) fa (forum shorthand) fadogia + tongkat stack (combo product context) fadogia-agrestis fadogia agrestis fadogiaagrestis fadogia black aphrodisiac baakin gagai libido hormone axis sexual function (discussed) free testosterone (discussed) total testosterone (discussed) luteinizing hormone (lh) support (discussed) libido hormone axis sexual function (discussed) free testosterone (discussed) total testosterone (discussed) luteinizing hormone (lh) support (discussed) performance continuity male vitality (discussed) morning wood / drive (community) natural t stack companion to tongkat (discussed) athletic recovery / training mood (discussed) anti-trt bridge or trt-avoidance self-experiment (discussed) libido hormone axis sexual function (discussed) free testosterone (discussed) total testosterone (discussed) luteinizing hormone (lh) support (discussed) fadogia agrestis is a shrub sold as an oral plant extract for libido and testosterone-related interest; human evidence remains limited. a six-week user reports better libido and erections without a testosterone rise on their bloodwork. testicular fullness in other posts is not proof of higher testosterone. fadogia is an oral plant extract discussed for libido and testosterone. reports include stronger sexual interest, no benefit, worse libido, anxiety or testicular aching. subjective improvement can coexist with unchanged testosterone. not trt, not a serm/ai, not enclomiphene, not hcg, not a sarm; extract ratio, plant part, solvent, and assay quality vary widely by brand. herbals in hormone discourse non-peptide systemic systemic oral plant extract discussed for libido and hormone effects; human efficacy, pharmacokinetics, and product equivalence are not established. systemic whole-body circulating", "legal_class": null }, { "id": 136, "slug": "boron", "name": "Boron", "aliases": [ "boron glycinate", "boron citrate", "boron aspartate", "boron gluconate", "boron amino acid chelate", "boron picolinate / ascorbate (less common labels)", "triple boron (citrate + aspartate + glycinate blends)", "tri-boron / Tri-Boron Plus (marketplace multi-salt brands)", "calcium fructoborate (CFB / plant-complex form; e.g. FruiteX-B marketing lineage)", "sodium borate / sodium tetraborate", "boric acid (research chemistry / some labels; also topical/vaginal niche)", "borax (household sodium tetraborate \u2014 not equivalent to measured supplement use)", "elemental boron (label math basis)" ], "type": "Non-peptide", "category": "Minerals in hormone discourse", "goals_use_cases": [ "libido", "hormone axis", "joints discussion", "free testosterone (discussed)", "SHBG modulation (discussed)", "estradiol balance talk (sex- and duration-dependent)", "joints / osteoarthritis discussion", "bone mineral support / osteopenia stacks (discussed)", "inflammation markers (hs-CRP, TNF-\u03b1, IL-6 discussed)", "vitamin D status / metabolite half-life talk", "magnesium absorption / urinary Mg conservation (discussed)", "urinary calcium conservation (discussed)", "performance continuity / multi-mineral stacks", "peri-postmenopause mineral talk (mixed symptom data)", "cognitive / alertness lore from depletion designs (secondary)", "wound-healing topical boric-acid niche (separate from oral free-T stacks)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "boron", "boron glycinate", "boron citrate", "boron aspartate", "boron gluconate", "boron amino acid chelate", "hormone axis", "free testosterone (discussed)", "shbg modulation (discussed)", "estradiol balance talk (sex- and duration-dependent)", "joints / osteoarthritis discussion", "bone mineral support / osteopenia stacks (discussed)" ], "feel_search": [ "hormone axis", "free testosterone (discussed)", "shbg modulation (discussed)", "estradiol balance talk (sex- and duration-dependent)", "joints / osteoarthritis discussion", "bone mineral support / osteopenia stacks (discussed)" ], "summary": "Boron is a dietary trace element sold in several supplement salts; biohackers discuss it for bone health and hormone-related symptoms.", "search_blob": "boron boron boron glycinate boron citrate boron aspartate boron gluconate boron amino acid chelate boron picolinate / ascorbate (less common labels) triple boron (citrate + aspartate + glycinate blends) tri-boron / tri-boron plus (marketplace multi-salt brands) calcium fructoborate (cfb / plant-complex form; e.g. fruitex-b marketing lineage) sodium borate / sodium tetraborate boric acid (research chemistry / some labels; also topical/vaginal niche) borax (household sodium tetraborate \u2014 not equivalent to measured supplement use) elemental boron (label math basis) boron boron glycinate boron citrate boron aspartate boron gluconate boron amino acid chelate hormone axis free testosterone (discussed) shbg modulation (discussed) estradiol balance talk (sex- and duration-dependent) joints / osteoarthritis discussion bone mineral support / osteopenia stacks (discussed) libido hormone axis joints discussion free testosterone (discussed) shbg modulation (discussed) estradiol balance talk (sex- and duration-dependent) joints / osteoarthritis discussion bone mineral support / osteopenia stacks (discussed) inflammation markers (hs-crp, tnf-\u03b1, il-6 discussed) vitamin d status / metabolite half-life talk magnesium absorption / urinary mg conservation (discussed) urinary calcium conservation (discussed) performance continuity / multi-mineral stacks peri-postmenopause mineral talk (mixed symptom data) cognitive / alertness lore from depletion designs (secondary) wound-healing topical boric-acid niche (separate from oral free-t stacks) hormone axis free testosterone (discussed) shbg modulation (discussed) estradiol balance talk (sex- and duration-dependent) joints / osteoarthritis discussion bone mineral support / osteopenia stacks (discussed) boron is a dietary trace element sold in several supplement salts; biohackers discuss it for bone health and hormone-related symptoms. one user reports lower libido during use and a rebound after stopping, while taking several other supplements. other comments report only a brief initial lift. boron is a dietary trace element sold in oral supplements and discussed for libido, hormone markers and joints. reports include improvement, fading benefits, no change and unwanted effects; a laboratory change does not necessarily mean feeling better. minerals in hormone discourse non-peptide systemic systemic oral trace mineral \u2014 whole-body hormone, bone, joint, vitamin d, magnesium/calcium conservation, and inflammatory-marker talk. systemic whole-body circulating", "legal_class": null }, { "id": 137, "slug": "clomiphene", "name": "Clomiphene", "aliases": [ "Clomid", "clomifene", "Clomiphene citrate", "Clomid (brand)", "Clomifene (INN-style spelling)", "Serophene (historical brand discussion)", "CC / Clom (clinic and forum shorthand)", "Clomiphene citrate USP 50 mg tablets" ], "type": "Non-peptide", "category": "Hormone modulators", "goals_use_cases": [ "hormone axis", "fertility discussion", "PCT discussion", "libido", "secondary hypogonadism discussion", "ovulation induction (approved female use)", "TRT alternative (discussed)", "energy / vitality (discussed)", "male infertility / oligospermia discussion", "sperm-parameter preservation vs exogenous T", "post-AAS HPTA restart talk" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "clomiphene", "Clomiphene citrate", "Clomid (brand)", "Clomifene (INN-style spelling)", "Serophene (historical brand discussion)", "CC / Clom (clinic and forum shorthand)", "hormone axis", "fertility discussion", "pct discussion", "libido", "secondary hypogonadism discussion", "ovulation induction (approved female use)" ], "feel_search": [ "hormone axis", "fertility discussion", "pct discussion", "libido", "secondary hypogonadism discussion", "ovulation induction (approved female use)" ], "summary": "Clomiphene (Clomid) is an oral selective estrogen receptor modulator used for ovulation induction and discussed in male fertility and testosterone care.", "search_blob": "clomiphene clomiphene clomid clomifene clomiphene citrate clomid (brand) clomifene (inn-style spelling) serophene (historical brand discussion) cc / clom (clinic and forum shorthand) clomiphene citrate usp 50 mg tablets clomiphene clomiphene citrate clomid (brand) clomifene (inn-style spelling) serophene (historical brand discussion) cc / clom (clinic and forum shorthand) hormone axis fertility discussion pct discussion libido secondary hypogonadism discussion ovulation induction (approved female use) hormone axis fertility discussion pct discussion libido secondary hypogonadism discussion ovulation induction (approved female use) trt alternative (discussed) energy / vitality (discussed) male infertility / oligospermia discussion sperm-parameter preservation vs exogenous t post-aas hpta restart talk hormone axis fertility discussion pct discussion libido secondary hypogonadism discussion ovulation induction (approved female use) clomiphene (clomid) is an oral selective estrogen receptor modulator used for ovulation induction and discussed in male fertility and testosterone care. a male-fertility thread includes low drive, depressed mood or irritability during use. one continuing user reports no depression but less energy than on testosterone. clomiphene is an oral serm used for ovulation induction and discussed off-label in men. reports include improved sexual function, unchanged symptoms despite higher testosterone, and mood or visual problems. community, clinic, and trial ranges are descriptive \u2014 not dosing advice, not a prescription, not a claim of safety for unsupervised use. hormone modulators non-peptide systemic systemic oral serm \u2014 a mixture of enclomiphene and longer-persisting zuclomiphene changes hypothalamic/pituitary estrogen feedback. systemic whole-body circulating", "legal_class": null }, { "id": 138, "slug": "cabergoline", "name": "Cabergoline", "aliases": [ "Dostinex", "caber", "Dostinex (Pfizer brand)", "caber (forum shorthand)", "Cabaser (some Parkinson\u2019s-market branding)", "Cabgolin (Sun Pharma generic branding, discussed)", "Apo-Cabergoline / ACT Cabergoline (Canadian generics)", "Cabergoline tablets 0.5 mg (scored)" ], "type": "Non-peptide", "category": "Hormone modulators", "goals_use_cases": [ "libido", "prolactin discussion", "libido adjacency", "prolactin control / hyperprolactinemia discussion", "libido / sexual function when prolactin is high", "AAS 19-nor adjacency (nandrolone / trenbolone prolactin lore)", "galactorrhea / lactation-type sides discussion", "pituitary prolactinoma research context", "post-cycle / on-cycle hormone side-management talk", "endocrine research (D2 agonist class)", "vs bromocriptine / pramipexole comparison searches" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "cabergoline", "Dostinex (Pfizer brand)", "caber (forum shorthand)", "Cabaser (some Parkinson\u2019s-market branding)", "Cabgolin (Sun Pharma generic branding, discussed)", "Apo-Cabergoline / ACT Cabergoline (Canadian generics)", "prolactin control / hyperprolactinemia discussion", "libido / sexual function when prolactin is high", "aas 19-nor adjacency (nandrolone / trenbolone prolactin lore)", "galactorrhea / lactation-type sides discussion", "pituitary prolactinoma research context", "post-cycle / on-cycle hormone side-management talk" ], "feel_search": [ "prolactin control / hyperprolactinemia discussion", "libido / sexual function when prolactin is high", "aas 19-nor adjacency (nandrolone / trenbolone prolactin lore)", "galactorrhea / lactation-type sides discussion", "pituitary prolactinoma research context", "post-cycle / on-cycle hormone side-management talk" ], "summary": "Cabergoline (Dostinex) is a long-acting dopamine D2 agonist used to lower prolactin, including in prolactinoma care.", "search_blob": "cabergoline cabergoline dostinex caber dostinex (pfizer brand) caber (forum shorthand) cabaser (some parkinson\u2019s-market branding) cabgolin (sun pharma generic branding, discussed) apo-cabergoline / act cabergoline (canadian generics) cabergoline tablets 0.5 mg (scored) cabergoline dostinex (pfizer brand) caber (forum shorthand) cabaser (some parkinson\u2019s-market branding) cabgolin (sun pharma generic branding, discussed) apo-cabergoline / act cabergoline (canadian generics) prolactin control / hyperprolactinemia discussion libido / sexual function when prolactin is high aas 19-nor adjacency (nandrolone / trenbolone prolactin lore) galactorrhea / lactation-type sides discussion pituitary prolactinoma research context post-cycle / on-cycle hormone side-management talk libido prolactin discussion libido adjacency prolactin control / hyperprolactinemia discussion libido / sexual function when prolactin is high aas 19-nor adjacency (nandrolone / trenbolone prolactin lore) galactorrhea / lactation-type sides discussion pituitary prolactinoma research context post-cycle / on-cycle hormone side-management talk endocrine research (d2 agonist class) vs bromocriptine / pramipexole comparison searches prolactin control / hyperprolactinemia discussion libido / sexual function when prolactin is high aas 19-nor adjacency (nandrolone / trenbolone prolactin lore) galactorrhea / lactation-type sides discussion pituitary prolactinoma research context post-cycle / on-cycle hormone side-management talk cabergoline (dostinex) is a long-acting dopamine d2 agonist used to lower prolactin, including in prolactinoma care. one patient describes relief of prolactinoma symptoms alongside headache, fatigue, brain fog and mood changes in week three. illness and life stress complicate attribution. cabergoline is an oral medicine that lowers prolactin. reports include returning desire or alertness, no improvement, nausea, dizziness, fatigue and unwanted mood or behavioral changes. hormone modulators non-peptide systemic oral dopamine agonist that lowers prolactin, with effects beyond the pituitary including dizziness, sleepiness and impulse-control changes. systemic whole-body circulating", "legal_class": null }, { "id": 139, "slug": "bpc-oral-argyline-adjacent", "name": "Oral BPC-157 formulations (arginate/salt debates)", "aliases": [ "BPC arginate", "stable oral BPC", "BPC-157 arginate salt", "BPC arginine salt", "Arg-BPC", "Pentadeca arginate", "PDA (pentadeca arginate)", "Bepecin di-L-arginine salt", "stable gastric BPC-157 (oral framing)", "oral BPC-157", "BPC-157 capsules", "BPC Rapid / BPC Delayed (capsule branding talk)", "Argyline (common misspelling; not Argireline skincare)" ], "type": "Peptide", "category": "Healing & repair", "goals_use_cases": [ "gut health", "recovery", "GI lining support (discussed)", "NSAID-related gut irritation talk", "IBS / IBD forum talk (not approved therapy)", "leaky-gut forum framing", "recovery (route-debated)", "injury repair (oral vs inject debate)", "soft-tissue healing (route comparison)", "inflammation (discussed)", "needle-free peptide interest", "maintenance after injectable block (discussed)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Mixed", "misspellings_search_terms": [ "bpc-oral-argyline-adjacent", "bpc oral argyline adjacent", "bpcoralargylineadjacent", "Oral BPC-157 formulations (arginate/salt debates)", "oral-bpc-157-formulations-(arginate/salt-debates)", "BPC arginate", "gut health", "gi lining support (discussed)", "nsaid-related gut irritation talk", "ibs / ibd forum talk (not approved therapy)", "leaky-gut forum framing", "recovery (route-debated)" ], "feel_search": [ "gut health", "gi lining support (discussed)", "nsaid-related gut irritation talk", "ibs / ibd forum talk (not approved therapy)", "leaky-gut forum framing", "recovery (route-debated)" ], "summary": "Oral BPC-157 products contain the same research peptide in capsule or other oral forms; arginate and acetate describe different salts.", "search_blob": "oral bpc-157 formulations (arginate/salt debates) bpc-oral-argyline-adjacent bpc arginate stable oral bpc bpc-157 arginate salt bpc arginine salt arg-bpc pentadeca arginate pda (pentadeca arginate) bepecin di-l-arginine salt stable gastric bpc-157 (oral framing) oral bpc-157 bpc-157 capsules bpc rapid / bpc delayed (capsule branding talk) argyline (common misspelling; not argireline skincare) bpc-oral-argyline-adjacent bpc oral argyline adjacent bpcoralargylineadjacent oral bpc-157 formulations (arginate/salt debates) oral-bpc-157-formulations-(arginate/salt-debates) bpc arginate gut health gi lining support (discussed) nsaid-related gut irritation talk ibs / ibd forum talk (not approved therapy) leaky-gut forum framing recovery (route-debated) gut health recovery gi lining support (discussed) nsaid-related gut irritation talk ibs / ibd forum talk (not approved therapy) leaky-gut forum framing recovery (route-debated) injury repair (oral vs inject debate) soft-tissue healing (route comparison) inflammation (discussed) needle-free peptide interest maintenance after injectable block (discussed) gut health gi lining support (discussed) nsaid-related gut irritation talk ibs / ibd forum talk (not approved therapy) leaky-gut forum framing recovery (route-debated) oral bpc-157 products contain the same research peptide in capsule or other oral forms; arginate and acetate describe different salts. one oral arginate user describes better sleep and less pain, then adds injections at week three. that later comparison cannot establish oral-versus-injected equivalence. oral bpc-157 products contain different salts and release formulations of the same peptide, discussed for gut discomfort and injury recovery. reports include relief, no change and worsening digestion; acid stability does not establish human absorption. healing & repair peptide mixed mixed and contested. mixed local systemic", "legal_class": null }, { "id": 140, "slug": "ghk-without-copper", "name": "GHK (without copper)", "aliases": [ "GHK peptide free base discussion", "GHK free base", "Free GHK", "GHK peptide (no copper)", "glycyl-L-histidyl-L-lysine", "Gly-His-Lys", "GHK tripeptide free form", "tripeptide-1 (cosmetic INCI free form)", "copper-free GHK", "GHK basic", "GHK alone" ], "type": "Peptide", "category": "Skin, hair & tissue remodeling", "goals_use_cases": [ "skin/hair", "recovery", "tissue remodeling discussion", "anti-aging discussion", "wound narratives", "copper-chelation / copper-avoidance interest", "cosmetic peptide comparison (free vs Cu complex)", "label / COA identity checks (wrong-product buys)", "stem-cell niche research talk (free vs Cu differentiation lore)", "research-only free-GHK animal cognition / gene work" ], "delivery_methods": [ "topical", "injection discussion" ], "discussion_popularity": "Emerging", "reach": "Mixed", "misspellings_search_terms": [ "ghk-without-copper", "ghk without copper", "ghkwithoutcopper", "GHK (without copper)", "ghk-(without-copper)", "GHK free base", "skin/hair", "recovery", "tissue remodeling discussion", "anti-aging discussion", "wound narratives", "copper-chelation / copper-avoidance interest" ], "feel_search": [ "skin/hair", "recovery", "tissue remodeling discussion", "anti-aging discussion", "wound narratives", "copper-chelation / copper-avoidance interest" ], "summary": "Copper-free GHK is the peptide part of GHK-Cu without copper already attached; free-GHK reports need to be kept separate from copper-peptide experiences.", "search_blob": "ghk (without copper) ghk-without-copper ghk peptide free base discussion ghk free base free ghk ghk peptide (no copper) glycyl-l-histidyl-l-lysine gly-his-lys ghk tripeptide free form tripeptide-1 (cosmetic inci free form) copper-free ghk ghk basic ghk alone ghk-without-copper ghk without copper ghkwithoutcopper ghk (without copper) ghk-(without-copper) ghk free base skin/hair recovery tissue remodeling discussion anti-aging discussion wound narratives copper-chelation / copper-avoidance interest skin/hair recovery tissue remodeling discussion anti-aging discussion wound narratives copper-chelation / copper-avoidance interest cosmetic peptide comparison (free vs cu complex) label / coa identity checks (wrong-product buys) stem-cell niche research talk (free vs cu differentiation lore) research-only free-ghk animal cognition / gene work skin/hair recovery tissue remodeling discussion anti-aging discussion wound narratives copper-chelation / copper-avoidance interest copper-free ghk is the peptide part of ghk-cu without copper already attached; free-ghk reports need to be kept separate from copper-peptide experiences. copper-free ghk is the glycine-histidine-lysine peptide supplied without copper already attached. reports include unspecified improvement, weak results and adverse symptoms, often with other products. skin, hair & tissue remodeling peptide mixed mixed \u2014 most free-ghk talk is topical, but sparse systemic injection reports and animal ip studies exist; do not substitute ghk-cu data. mixed local systemic", "legal_class": null }, { "id": 141, "slug": "ahk-cu", "name": "AHK-Cu", "aliases": [ "AHK copper peptide", "Ala-His-Lys copper", "AHK-Cu copper tripeptide", "L-alanyl-L-histidyl-L-lysine-Cu2+", "copper AHK", "copper tripeptide-3 (cosmetic INCI / supplier contexts)", "tripeptide-copper complex (AHK context)", "Ala-His-Lys-Cu" ], "type": "Peptide", "category": "Skin, hair & tissue remodeling", "goals_use_cases": [ "skin/hair", "hair density narratives", "scalp / follicle discussion", "aesthetic remodeling", "anti-aging discussion (by analogy to GHK-Cu)", "cosmetic copper-peptide interest", "DIY topical hair-serum culture", "GHK-Cu comparison / dual-copper stacks" ], "delivery_methods": [ "topical" ], "discussion_popularity": "Emerging", "reach": "Local", "misspellings_search_terms": [ "ahk-cu", "ahk cu", "ahkcu", "AHK copper peptide", "Ala-His-Lys copper", "AHK-Cu copper tripeptide", "scalp serum", "copper peptide hair", "tiktok inject", "dual copper", "ordinary serum", "blue tint", "vs ghk", "copper tripeptide-3" ], "feel_search": [ "scalp serum", "copper peptide hair", "tiktok inject", "dual copper", "ordinary serum", "blue tint", "vs ghk", "copper tripeptide-3" ], "summary": "AHK-Cu is a copper-binding tripeptide studied for hair biology and used in experimental topical hair products.", "search_blob": "ahk-cu ahk-cu ahk copper peptide ala-his-lys copper ahk-cu copper tripeptide l-alanyl-l-histidyl-l-lysine-cu2+ copper ahk copper tripeptide-3 (cosmetic inci / supplier contexts) tripeptide-copper complex (ahk context) ala-his-lys-cu ahk-cu ahk cu ahkcu ahk copper peptide ala-his-lys copper ahk-cu copper tripeptide scalp serum copper peptide hair tiktok inject dual copper ordinary serum blue tint vs ghk copper tripeptide-3 skin/hair hair density narratives scalp / follicle discussion aesthetic remodeling anti-aging discussion (by analogy to ghk-cu) cosmetic copper-peptide interest diy topical hair-serum culture ghk-cu comparison / dual-copper stacks scalp serum copper peptide hair tiktok inject dual copper ordinary serum blue tint vs ghk copper tripeptide-3 ahk-cu is a copper-binding tripeptide studied for hair biology and used in experimental topical hair products. one topical user reports baby hairs and reduced shedding after months, while also using minoxidil, alfatradiol and microneedling. ahk-cu's contribution is unclear. ahk-cu is a copper-binding peptide discussed for scalp hair. reports include thicker-feeling hair, possible growth, no change and irritation, often with other hair treatments. injection accounts remain separate and uncertain. the 2026 discussions compare topical use with injection. the foundational hair study used isolated follicles and cultured cells; it did not test injections in people. skin, hair & tissue remodeling peptide local mainly topical scalp use; sparse injection accounts describe a different, poorly characterized exposure. local site pin topical", "legal_class": null }, { "id": 142, "slug": "copper-tripeptide-variants", "name": "Copper tripeptide variants (cosmetic research)", "aliases": [ "copper peptides class", "Cu-GHK family products", "copper tripeptide-1 family", "GHK-Cu analogs / variants", "AHK-Cu (related copper tripeptide)", "copper tripeptide-3 (AHK-Cu cosmetic talk)", "cosmetic copper peptides", "carrier copper peptides", "GHK without copper (adjacent, not Cu-complex)" ], "type": "Peptide", "category": "Skin, hair & tissue remodeling", "goals_use_cases": [ "skin/hair", "anti-aging discussion", "collagen / firmness talk", "texture & tone narratives", "scalp / hair appearance", "cosmetic matrix remodeling", "post-procedure recovery talk", "wound / scar adjacency (literature more than DIY)", "Glow / KLOW stack copper leg (injectable adjacency)" ], "delivery_methods": [ "topical" ], "discussion_popularity": "Emerging", "reach": "Local", "misspellings_search_terms": [ "copper-tripeptide-variants", "copper tripeptide variants", "coppertripeptidevariants", "Copper tripeptide variants (cosmetic research)", "copper-tripeptide-variants-(cosmetic-research)", "copper peptides class", "skin/hair", "anti-aging discussion", "collagen / firmness talk", "texture & tone narratives", "scalp / hair appearance", "cosmetic matrix remodeling" ], "feel_search": [ "skin/hair", "anti-aging discussion", "collagen / firmness talk", "texture & tone narratives", "scalp / hair appearance", "cosmetic matrix remodeling" ], "summary": "Copper peptide products include different molecules such as GHK-Cu and AHK-Cu, used in skin and hair cosmetics and experimental preparations.", "search_blob": "copper tripeptide variants (cosmetic research) copper-tripeptide-variants copper peptides class cu-ghk family products copper tripeptide-1 family ghk-cu analogs / variants ahk-cu (related copper tripeptide) copper tripeptide-3 (ahk-cu cosmetic talk) cosmetic copper peptides carrier copper peptides ghk without copper (adjacent, not cu-complex) copper-tripeptide-variants copper tripeptide variants coppertripeptidevariants copper tripeptide variants (cosmetic research) copper-tripeptide-variants-(cosmetic-research) copper peptides class skin/hair anti-aging discussion collagen / firmness talk texture & tone narratives scalp / hair appearance cosmetic matrix remodeling skin/hair anti-aging discussion collagen / firmness talk texture & tone narratives scalp / hair appearance cosmetic matrix remodeling post-procedure recovery talk wound / scar adjacency (literature more than diy) glow / klow stack copper leg (injectable adjacency) skin/hair anti-aging discussion collagen / firmness talk texture & tone narratives scalp / hair appearance cosmetic matrix remodeling copper peptide products include different molecules such as ghk-cu and ahk-cu, used in skin and hair cosmetics and experimental preparations. a ghk-cu serum user reports new fine lines after about ten days and stops. that experience does not establish the same reaction for ahk-cu or injected products. copper tripeptides include ghk-cu and ahk-cu, different copper-binding peptides used in skin and scalp products. reports include smoother or plumper-looking skin, no visible change, irritation and worse-looking skin; whole formulas and routes differ. skin, hair & tissue remodeling peptide local mostly local topicals; systemic injection talk belongs chiefly to ghk-cu or glow/klow blends, not every copper-peptide variant. local site pin topical", "legal_class": null }, { "id": 143, "slug": "mots-c-analogs", "name": "MOTS-c analogs / MDP class talk", "aliases": [ "mitochondrial-derived peptide class", "MOTS-c analogs", "CB4211", "CB-4211", "CB 4211", "MDP class", "MDP peptides", "MOTS-c derivatives", "mitochondrial ORF peptide analogs", "mitochondria based therapeutics", "MBT peptides (CohBar)", "CB5138", "CB5064 analogs", "MBT5 analogs", "MOTS-c analogue" ], "type": "Peptide", "category": "Mitochondrial & metabolic peptides", "goals_use_cases": [ "metabolic health", "longevity", "insulin sensitivity (discussed)", "longevity / healthspan", "mitochondrial function", "NAFLD / NASH / fatty liver research interest", "obesity / weight research interest (analog path)", "exercise mimetic narratives", "healthy aging / healthspan", "body recomposition (discussed)", "glucose handling / metabolic flexibility", "fibrosis research interest (other CohBar MDP assets)", "vendor \u201cimproved MOTS-c\u201d label shopping" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "mots-c-analogs", "mots c analogs", "motscanalogs", "MOTS-c analogs / MDP class talk", "mots-c-analogs-/-mdp-class-talk", "MOTS-c analogs", "metabolic health", "insulin sensitivity (discussed)", "longevity / healthspan", "mitochondrial function", "nafld / nash / fatty liver research interest", "obesity / weight research interest (analog path)" ], "feel_search": [ "metabolic health", "insulin sensitivity (discussed)", "longevity / healthspan", "mitochondrial function", "nafld / nash / fatty liver research interest", "obesity / weight research interest (analog path)" ], "summary": "MOTS-c analogs are modified mitochondrial-peptide candidates, including CB4211; this is a family of products, not one interchangeable compound.", "search_blob": "mots-c analogs / mdp class talk mots-c-analogs mitochondrial-derived peptide class mots-c analogs cb4211 cb-4211 cb 4211 mdp class mdp peptides mots-c derivatives mitochondrial orf peptide analogs mitochondria based therapeutics mbt peptides (cohbar) cb5138 cb5064 analogs mbt5 analogs mots-c analogue mots-c-analogs mots c analogs motscanalogs mots-c analogs / mdp class talk mots-c-analogs-/-mdp-class-talk mots-c analogs metabolic health insulin sensitivity (discussed) longevity / healthspan mitochondrial function nafld / nash / fatty liver research interest obesity / weight research interest (analog path) metabolic health longevity insulin sensitivity (discussed) longevity / healthspan mitochondrial function nafld / nash / fatty liver research interest obesity / weight research interest (analog path) exercise mimetic narratives healthy aging / healthspan body recomposition (discussed) glucose handling / metabolic flexibility fibrosis research interest (other cohbar mdp assets) vendor \u201cimproved mots-c\u201d label shopping metabolic health insulin sensitivity (discussed) longevity / healthspan mitochondrial function nafld / nash / fatty liver research interest obesity / weight research interest (analog path) mots-c analogs are modified mitochondrial-peptide candidates, including cb4211; this is a family of products, not one interchangeable compound. analog-specific experience is sparse. most shared energy or fatigue stories concern parent mots-c; cb4211 injection-site reactions are a separate clinical finding. mots-c analogs are modified mitochondrial signaling peptides. most shared energy, endurance, fatigue and no-response accounts concern native mots-c, not authenticated analog exposure. mitochondrial & metabolic peptides peptide systemic systemic \u2014 whole-body energy, insulin, and mitochondrial signaling class. systemic whole-body circulating", "legal_class": null }, { "id": 144, "slug": "5-aminoimidazole-class", "name": "AICAR (AMPK discourse)", "aliases": [ "AICAR", "acadesine", "AICAr", "AICA-R", "AICA riboside", "AICA ribonucleoside", "5-aminoimidazole-4-carboxamide-1-\u03b2-D-ribofuranoside", "5-aminoimidazole-4-carboxamide riboside", "5-amino-4-imidazolecarboxamide ribonucleoside", "AICA ribonucleotide (endogenous phosphorylated form / nomenclature clash)", "ZMP (intracellular AICAR monophosphate / Z-nucleotide)", "Z-riboside", "CAS 2627-69-2", "exercise-in-a-pill AICAR (media nickname)" ], "type": "Non-peptide", "category": "Metabolic research compounds", "goals_use_cases": [ "endurance", "metabolic health", "performance", "endurance / running capacity (preclinical + community)", "exercise-mimetic / \u201cexercise-in-a-pill\u201d narrative", "fat oxidation / metabolic reprogramming (preclinical)", "AMPK pathway research tool", "insulin sensitivity / glucose uptake research (preclinical + limited human IV)", "mitochondrial / oxidative muscle gene programs (preclinical)", "performance continuity / steady-state cardio assist (community)", "body recomposition assist under diet (community, weak solo signal)", "cardiac ischemia / CABG historical drug development (acadesine)", "hematologic malignancy research history (CLL, MDS/AML IV trials)", "anti-doping / WADA metabolic-modulator literacy" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "5-aminoimidazole-class", "5 aminoimidazole class", "5aminoimidazoleclass", "AICAR (AMPK discourse)", "aicar-(ampk-discourse)", "AICAR", "endurance / running capacity (preclinical + community)", "exercise-mimetic / \u201cexercise-in-a-pill\u201d narrative", "fat oxidation / metabolic reprogramming (preclinical)", "ampk pathway research tool", "insulin sensitivity / glucose uptake research (preclinical + limited human iv)", "mitochondrial / oxidative muscle gene programs (preclinical)" ], "feel_search": [ "endurance / running capacity (preclinical + community)", "exercise-mimetic / \u201cexercise-in-a-pill\u201d narrative", "fat oxidation / metabolic reprogramming (preclinical)", "ampk pathway research tool", "insulin sensitivity / glucose uptake research (preclinical + limited human iv)", "mitochondrial / oxidative muscle gene programs (preclinical)" ], "summary": "AICAR, also called acadesine, is a non-peptide nucleoside studied for metabolic signaling and discussed as an endurance aid.", "search_blob": "aicar (ampk discourse) 5-aminoimidazole-class aicar acadesine aicar aica-r aica riboside aica ribonucleoside 5-aminoimidazole-4-carboxamide-1-\u03b2-d-ribofuranoside 5-aminoimidazole-4-carboxamide riboside 5-amino-4-imidazolecarboxamide ribonucleoside aica ribonucleotide (endogenous phosphorylated form / nomenclature clash) zmp (intracellular aicar monophosphate / z-nucleotide) z-riboside cas 2627-69-2 exercise-in-a-pill aicar (media nickname) 5-aminoimidazole-class 5 aminoimidazole class 5aminoimidazoleclass aicar (ampk discourse) aicar-(ampk-discourse) aicar endurance / running capacity (preclinical + community) exercise-mimetic / \u201cexercise-in-a-pill\u201d narrative fat oxidation / metabolic reprogramming (preclinical) ampk pathway research tool insulin sensitivity / glucose uptake research (preclinical + limited human iv) mitochondrial / oxidative muscle gene programs (preclinical) endurance metabolic health performance endurance / running capacity (preclinical + community) exercise-mimetic / \u201cexercise-in-a-pill\u201d narrative fat oxidation / metabolic reprogramming (preclinical) ampk pathway research tool insulin sensitivity / glucose uptake research (preclinical + limited human iv) mitochondrial / oxidative muscle gene programs (preclinical) performance continuity / steady-state cardio assist (community) body recomposition assist under diet (community, weak solo signal) cardiac ischemia / cabg historical drug development (acadesine) hematologic malignancy research history (cll, mds/aml iv trials) anti-doping / wada metabolic-modulator literacy endurance / running capacity (preclinical + community) exercise-mimetic / \u201cexercise-in-a-pill\u201d narrative fat oxidation / metabolic reprogramming (preclinical) ampk pathway research tool insulin sensitivity / glucose uptake research (preclinical + limited human iv) mitochondrial / oxidative muscle gene programs (preclinical) aicar, also called acadesine, is a non-peptide nucleoside studied for metabolic signaling and discussed as an endurance aid. the inspected stacked-use log reports little overall difference and credits the speedy, hot feeling to helios. it does not establish an aicar-only feel. aicar, or acadesine, is a nucleoside studied for metabolic signaling. some stacked accounts report easier cardio or steady energy; others report little change or feeling unwell. they do not isolate aicar's contribution. metabolic research compounds non-peptide systemic systemic \u2014 aicar/acadesine is a nucleoside converted inside cells to zmp; not a peptide, local endurance injection or class-wide exposure model. systemic whole-body circulating", "legal_class": null }, { "id": 145, "slug": "gw0742", "name": "GW0742", "aliases": [ "PPAR\u03b4 agonist research", "GW-0742", "GW 0742", "GW610742", "GW-610742", "Fitorine", "Lipoline (forum trade nicknames)", "Super Cardarine (community nickname)", "Advanced Cardio (vendor branding)" ], "type": "Non-peptide", "category": "Metabolic research compounds", "goals_use_cases": [ "endurance", "fat loss discussion", "endurance / cardio capacity discussion", "fat loss / recomp adjacency (community)", "metabolic / fuel-preference research", "lipid profile / reverse cholesterol transport (preclinical)", "insulin-sensitivity / HOMA-IR research (preclinical)", "inflammation models (preclinical)", "performance / non-androgenic cutting stacks", "Cardarine (GW501516) alternative or sequential trial" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "gw0742", "GW-0742", "GW 0742", "GW610742", "GW-610742", "Fitorine", "endurance / cardio capacity discussion", "fat loss / recomp adjacency (community)", "metabolic / fuel-preference research", "lipid profile / reverse cholesterol transport (preclinical)", "insulin-sensitivity / homa-ir research (preclinical)", "inflammation models (preclinical)" ], "feel_search": [ "endurance / cardio capacity discussion", "fat loss / recomp adjacency (community)", "metabolic / fuel-preference research", "lipid profile / reverse cholesterol transport (preclinical)", "insulin-sensitivity / homa-ir research (preclinical)", "inflammation models (preclinical)" ], "summary": "GW0742 is an experimental PPAR-delta/beta activator related to cardarine, discussed for endurance and fat metabolism.", "search_blob": "gw0742 gw0742 ppar\u03b4 agonist research gw-0742 gw 0742 gw610742 gw-610742 fitorine lipoline (forum trade nicknames) super cardarine (community nickname) advanced cardio (vendor branding) gw0742 gw-0742 gw 0742 gw610742 gw-610742 fitorine endurance / cardio capacity discussion fat loss / recomp adjacency (community) metabolic / fuel-preference research lipid profile / reverse cholesterol transport (preclinical) insulin-sensitivity / homa-ir research (preclinical) inflammation models (preclinical) endurance fat loss discussion endurance / cardio capacity discussion fat loss / recomp adjacency (community) metabolic / fuel-preference research lipid profile / reverse cholesterol transport (preclinical) insulin-sensitivity / homa-ir research (preclinical) inflammation models (preclinical) performance / non-androgenic cutting stacks cardarine (gw501516) alternative or sequential trial endurance / cardio capacity discussion fat loss / recomp adjacency (community) metabolic / fuel-preference research lipid profile / reverse cholesterol transport (preclinical) insulin-sensitivity / homa-ir research (preclinical) inflammation models (preclinical) gw0742 is an experimental ppar-delta/beta activator related to cardarine, discussed for endurance and fat metabolism. endurance reports are mixed, including no benefit. some describe headache, nausea, fatigue or racing/irregular heartbeat; later positive accounts often involve changed schedules or other compounds. gw0742 is an experimental ppar-delta/beta activator discussed for endurance and fuel metabolism. reports include easier cardio, no endurance improvement, fatigue and racing or irregular heartbeat; stronger-than-cardarine marketing does not establish better outcomes. metabolic research compounds non-peptide systemic systemic \u2014 a whole-body selective ppar\u03b4/\u03b2 agonist discussed as shifting muscle fuel use toward fatty-acid oxidation, not a local or injection-site agent. systemic whole-body circulating", "legal_class": null }, { "id": 147, "slug": "acp-105", "name": "ACP-105", "aliases": [ "ACP105", "ACP 105", "Acadia SARM ACP-105", "non-steroidal SARM ACP-105", "2-chloro-4-[(3-endo)-3-hydroxy-3-methyl-8-azabicyclo[3.2.1]oct-8-yl]-3-methylbenzonitrile", "CAS 1048998-11-3" ], "type": "Non-peptide", "category": "SARMs (adjacent discourse)", "goals_use_cases": [ "muscle growth", "performance", "lean mass (discussed)", "recomposition (discussed)", "cutting / dry look (discussed)", "bone support (preclinical interest)", "strength continuity (discussed)", "body composition", "milder oral SARM alternative (community framing)", "age-related cognitive decline research context (preclinical only)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "acp-105", "acp 105", "acp105", "Acadia SARM ACP-105", "non-steroidal SARM ACP-105", "2-chloro-4-[(3-endo)-3-hydroxy-3-methyl-8-azabicyclo[3.2.1]oct-8-yl]-3-methylbenzonitrile", "muscle growth", "performance", "lean mass (discussed)", "recomposition (discussed)", "cutting / dry look (discussed)", "bone support (preclinical interest)" ], "feel_search": [ "muscle growth", "performance", "lean mass (discussed)", "recomposition (discussed)", "cutting / dry look (discussed)", "bone support (preclinical interest)" ], "summary": "ACP-105 is an experimental oral SARM discussed for muscle retention, pumps and a drier appearance. Reports include stronger or weaker workouts, no benefit and sleep disruption.", "search_blob": "acp-105 acp-105 acp105 acp 105 acadia sarm acp-105 non-steroidal sarm acp-105 2-chloro-4-[(3-endo)-3-hydroxy-3-methyl-8-azabicyclo[3.2.1]oct-8-yl]-3-methylbenzonitrile cas 1048998-11-3 acp-105 acp 105 acp105 acadia sarm acp-105 non-steroidal sarm acp-105 2-chloro-4-[(3-endo)-3-hydroxy-3-methyl-8-azabicyclo[3.2.1]oct-8-yl]-3-methylbenzonitrile muscle growth performance lean mass (discussed) recomposition (discussed) cutting / dry look (discussed) bone support (preclinical interest) muscle growth performance lean mass (discussed) recomposition (discussed) cutting / dry look (discussed) bone support (preclinical interest) strength continuity (discussed) body composition milder oral sarm alternative (community framing) age-related cognitive decline research context (preclinical only) muscle growth performance lean mass (discussed) recomposition (discussed) cutting / dry look (discussed) bone support (preclinical interest) acp-105 is an experimental oral sarm discussed for muscle retention, pumps and a drier appearance. reports include stronger or weaker workouts, no benefit and sleep disruption. a detailed log describes early headache, restless sleep and energy, then gym pumps. illness and other medicines complicate its later adverse-event account. acp-105 is an experimental oral sarm discussed for muscle retention, pumps and a drier appearance. reports include stronger or weaker workouts, no benefit and sleep disruption. forum mg charts, 12\u201316 h half-life memes, and \u201cmilder than lgd\u201d lore are discussion data \u2014 not verified human pk or head-to-head trials. sarms (adjacent discourse) non-peptide systemic systemic oral sarm \u2014 muscle/bone selectivity comes from preclinical work, not local targeting or proof of a safe steroid replacement. systemic whole-body circulating", "legal_class": null }, { "id": 148, "slug": "ligandrol-recomp-stacks", "name": "Ligandrol recomp stacks (SARM multi-agent culture)", "aliases": [ "SARM stacks", "RAD+LGD culture threads", "LGD recomp stacks", "Ligandrol stack", "LGD-4033 stacks", "LGD + RAD stack", "LGD + ostarine stack", "LGD + Cardarine stack", "LGD + MK-677 stack", "SARM stack culture (multi-agent discussion unit)", "multi-SARM recomp cycle", "kitchen-sink SARM blend" ], "type": "Non-peptide", "category": "SARMs (adjacent discourse)", "goals_use_cases": [ "muscle growth", "performance", "fat loss", "body recomposition (simultaneous fat loss + muscle hold/gain, primary community framing)", "muscle growth / lean bulk with oral multi-agent stacks", "strength and progressive overload under deficit or near-maintenance", "cutting with muscle retention (community \u201chold size while cutting\u201d)", "performance / conditioning when Cardarine or similar is co-logged", "bulk-to-recomp and recomp-to-cut seasonal transitions", "\u201csteroid-like results without injectables\u201d marketing narrative (unproven safety equivalence)", "attribution of aesthetic look (fuller LGD vs drier RAD/ostarine typology)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "ligandrol-recomp-stacks", "ligandrol recomp stacks", "ligandrolrecompstacks", "Ligandrol recomp stacks (SARM multi-agent culture)", "ligandrol-recomp-stacks-(sarm-multi-agent-culture)", "SARM stacks", "body recomposition (simultaneous fat loss + muscle hold/gain, primary community framing)", "muscle growth / lean bulk with oral multi-agent stacks", "strength and progressive overload under deficit or near-maintenance", "cutting with muscle retention (community \u201chold size while cutting\u201d)", "performance / conditioning when cardarine or similar is co-logged", "bulk-to-recomp and recomp-to-cut seasonal transitions" ], "feel_search": [ "body recomposition (simultaneous fat loss + muscle hold/gain, primary community framing)", "muscle growth / lean bulk with oral multi-agent stacks", "strength and progressive overload under deficit or near-maintenance", "cutting with muscle retention (community \u201chold size while cutting\u201d)", "performance / conditioning when cardarine or similar is co-logged", "bulk-to-recomp and recomp-to-cut seasonal transitions" ], "summary": "Ligandrol recomp stacks are combinations built around LGD-4033, discussed for losing fat while retaining or gaining muscle; they are not one standardized product.", "search_blob": "ligandrol recomp stacks (sarm multi-agent culture) ligandrol-recomp-stacks sarm stacks rad+lgd culture threads lgd recomp stacks ligandrol stack lgd-4033 stacks lgd + rad stack lgd + ostarine stack lgd + cardarine stack lgd + mk-677 stack sarm stack culture (multi-agent discussion unit) multi-sarm recomp cycle kitchen-sink sarm blend ligandrol-recomp-stacks ligandrol recomp stacks ligandrolrecompstacks ligandrol recomp stacks (sarm multi-agent culture) ligandrol-recomp-stacks-(sarm-multi-agent-culture) sarm stacks body recomposition (simultaneous fat loss + muscle hold/gain, primary community framing) muscle growth / lean bulk with oral multi-agent stacks strength and progressive overload under deficit or near-maintenance cutting with muscle retention (community \u201chold size while cutting\u201d) performance / conditioning when cardarine or similar is co-logged bulk-to-recomp and recomp-to-cut seasonal transitions muscle growth performance fat loss body recomposition (simultaneous fat loss + muscle hold/gain, primary community framing) muscle growth / lean bulk with oral multi-agent stacks strength and progressive overload under deficit or near-maintenance cutting with muscle retention (community \u201chold size while cutting\u201d) performance / conditioning when cardarine or similar is co-logged bulk-to-recomp and recomp-to-cut seasonal transitions \u201csteroid-like results without injectables\u201d marketing narrative (unproven safety equivalence) attribution of aesthetic look (fuller lgd vs drier rad/ostarine typology) body recomposition (simultaneous fat loss + muscle hold/gain, primary community framing) muscle growth / lean bulk with oral multi-agent stacks strength and progressive overload under deficit or near-maintenance cutting with muscle retention (community \u201chold size while cutting\u201d) performance / conditioning when cardarine or similar is co-logged bulk-to-recomp and recomp-to-cut seasonal transitions ligandrol recomp stacks are combinations built around lgd-4033, discussed for losing fat while retaining or gaining muscle; they are not one standardized product. reports depend on the partners: one lgd/ostarine user described definition and mostly water-weight gain, while another testosterone/lgd/rad user reported severe erectile dysfunction. there is no single stack response. ligandrol recomp stacks are combinations built around lgd for muscle and fat-loss goals. reports include strength, fullness, less soreness, little added benefit, fatigue and sexual or mood problems. there is no single stack response. sarms (adjacent discourse) non-peptide systemic systemic oral multi-agent stacks \u2014 whole-body androgen-receptor (and often non-sarm adjunct) exposure. systemic whole-body circulating", "legal_class": null }, { "id": 149, "slug": "ta-65", "name": "TA-65", "aliases": [ "TA65", "cycloastragenol", "telomerase activation discussion", "TA-65MD", "TA-65 MD", "cycloastragenol (related active / class discussion)", "TAT2 (research synonym in older literature)", "Astragalus root extract (branded telomerase-activator product)", "telomerase activator 65", "T.A. Sciences TA-65", "CAG (cycloastragenol shorthand in literature)" ], "type": "Non-peptide", "category": "Longevity & cellular energy", "goals_use_cases": [ "longevity", "telomere discussion", "anti-aging discussion", "immune aging / immunosenescence talk", "cellular energy / vitality narratives", "healthspan biomarkers (discussed)", "metabolic syndrome marker interest", "post-MI immune / inflammation talk (clinical pilot)", "skin fitness narratives (oral minority; topical TA-65 for Skin product line)", "cardiovascular risk-marker interest (HDL / inflammation)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "ta-65", "ta 65", "ta65", "TA-65MD", "TA-65 MD", "cycloastragenol (related active / class discussion)", "longevity", "telomere discussion", "anti-aging discussion", "immune aging / immunosenescence talk", "cellular energy / vitality narratives", "healthspan biomarkers (discussed)" ], "feel_search": [ "longevity", "telomere discussion", "anti-aging discussion", "immune aging / immunosenescence talk", "cellular energy / vitality narratives", "healthspan biomarkers (discussed)" ], "summary": "TA-65 is a branded oral Astragalus-derived supplement marketed as a telomerase activator for longevity-related interests.", "search_blob": "ta-65 ta-65 ta65 cycloastragenol telomerase activation discussion ta-65md ta-65 md cycloastragenol (related active / class discussion) tat2 (research synonym in older literature) astragalus root extract (branded telomerase-activator product) telomerase activator 65 t.a. sciences ta-65 cag (cycloastragenol shorthand in literature) ta-65 ta 65 ta65 ta-65md ta-65 md cycloastragenol (related active / class discussion) longevity telomere discussion anti-aging discussion immune aging / immunosenescence talk cellular energy / vitality narratives healthspan biomarkers (discussed) longevity telomere discussion anti-aging discussion immune aging / immunosenescence talk cellular energy / vitality narratives healthspan biomarkers (discussed) metabolic syndrome marker interest post-mi immune / inflammation talk (clinical pilot) skin fitness narratives (oral minority; topical ta-65 for skin product line) cardiovascular risk-marker interest (hdl / inflammation) longevity telomere discussion anti-aging discussion immune aging / immunosenescence talk cellular energy / vitality narratives healthspan biomarkers (discussed) ta-65 is a branded oral astragalus-derived supplement marketed as a telomerase activator for longevity-related interests. one older forum user described strength benefits that later faded, while also using another product and dealing with anemia. ta-65 is a branded oral astragalus-derived supplement discussed for telomeres and aging. users report strength or dream changes, fading benefits or no noticeable change; these experiences do not establish longer life. longevity & cellular energy non-peptide systemic systemic oral telomerase-pathway supplement (branded cycloastragenol-class capsule); whole-body longevity and immune-aging talk. systemic whole-body circulating", "legal_class": null }, { "id": 150, "slug": "astaxanthin-biohack", "name": "Astaxanthin", "aliases": [ "astroxanthin misspelling common", "Haematococcus extract", "ASX", "AST", "AX", "Astaxanthine", "Astaxanthin (biohacking adjacency)", "Haematococcus pluvialis extract", "Haematococcus lacustris extract", "Natural astaxanthin (algae-derived)", "Synthetic astaxanthin", "Astaxanthin esters", "Astaxanthin mono-/diesters", "AstaREAL / BioAstin-style algal products (brand family talk)", "3S,3'S astaxanthin" ], "type": "Non-peptide", "category": "Antioxidant & performance adjacents", "goals_use_cases": [ "skin/hair", "recovery", "eye health discussion", "inflammation discussion", "skin/hair / photoaging adjacency", "recovery / DOMS discussion", "eye health / digital eye-strain discussion", "mild dry-eye discussion", "inflammation / oxidative-stress marker talk", "antioxidant support (discussed)", "UV / erythema resilience adjacency", "exercise endurance / cycling performance adjacency", "longevity / healthy aging (discussed)", "cognitive / psychomotor minority signal", "cardiometabolic marker adjacency (BP, lipids \u2014 sparse)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "astaxanthin-biohack", "astaxanthin biohack", "astaxanthinbiohack", "Astaxanthin", "ASX", "AST", "skin/hair / photoaging adjacency", "recovery / doms discussion", "eye health / digital eye-strain discussion", "mild dry-eye discussion", "inflammation / oxidative-stress marker talk", "antioxidant support (discussed)" ], "feel_search": [ "skin/hair / photoaging adjacency", "recovery / doms discussion", "eye health / digital eye-strain discussion", "mild dry-eye discussion", "inflammation / oxidative-stress marker talk", "antioxidant support (discussed)" ], "summary": "Astaxanthin is a red-orange carotenoid, usually sold in algae-derived capsules for skin, eye and antioxidant interests.", "search_blob": "astaxanthin astaxanthin-biohack astroxanthin misspelling common haematococcus extract asx ast ax astaxanthine astaxanthin (biohacking adjacency) haematococcus pluvialis extract haematococcus lacustris extract natural astaxanthin (algae-derived) synthetic astaxanthin astaxanthin esters astaxanthin mono-/diesters astareal / bioastin-style algal products (brand family talk) 3s,3's astaxanthin astaxanthin-biohack astaxanthin biohack astaxanthinbiohack astaxanthin asx ast skin/hair / photoaging adjacency recovery / doms discussion eye health / digital eye-strain discussion mild dry-eye discussion inflammation / oxidative-stress marker talk antioxidant support (discussed) skin/hair recovery eye health discussion inflammation discussion skin/hair / photoaging adjacency recovery / doms discussion eye health / digital eye-strain discussion mild dry-eye discussion inflammation / oxidative-stress marker talk antioxidant support (discussed) uv / erythema resilience adjacency exercise endurance / cycling performance adjacency longevity / healthy aging (discussed) cognitive / psychomotor minority signal cardiometabolic marker adjacency (bp, lipids \u2014 sparse) skin/hair / photoaging adjacency recovery / doms discussion eye health / digital eye-strain discussion mild dry-eye discussion inflammation / oxidative-stress marker talk antioxidant support (discussed) astaxanthin is a red-orange carotenoid, usually sold in algae-derived capsules for skin, eye and antioxidant interests. one gel-cap user reports early acne and workout changes, then worries about libido, while explicitly acknowledging placebo or nocebo. this is not proof of hormone suppression. astaxanthin is a red-orange carotenoid discussed for skin, eye comfort and recovery. reports range from perceived benefit to no change, sleep problems or digestive symptoms. antioxidant & performance adjacents non-peptide systemic systemic oral fat-soluble xanthophyll carotenoid (c40h52o4); lipoprotein-carried plasma exposure with tissue lag for skin/eyes/muscle. systemic whole-body circulating", "legal_class": null }, { "id": 151, "slug": "wolverine-stack", "name": "Wolverine stack", "aliases": [ "Wolverine blend", "BPC-157 + TB-500", "BPC TB stack", "wolverine peptide stack", "BPC/TB stack", "healing stack (BPC+TB)", "Wolverine peptide blend", "BPC-157/TB-500 combo" ], "type": "Peptide", "category": "Healing stacks (named blends)", "goals_use_cases": [ "recovery", "injury repair", "joints & tendons", "soft-tissue healing", "performance continuity", "inflammation discussion", "post-strain bounce-back", "ligament / tendon irritation talk", "mobility continuity under training load" ], "delivery_methods": [ "subcutaneous", "separate vials or pre-mixed blend" ], "discussion_popularity": "High", "reach": "Mixed", "misspellings_search_terms": [ "wolverine-stack", "wolverine stack", "wolverinestack", "Wolverine blend", "BPC-157 + TB-500", "BPC/TB stack", "injury", "tendon", "wolverine", "recovery", "pcac", "503a", "compounding", "fda approved", "wolverine nasal", "bpc tb nasal", "nasal", "site pin", "flu-ish" ], "feel_search": [ "injury", "tendon", "wolverine", "recovery", "nasal", "site pin", "flu-ish" ], "summary": "The Wolverine stack combines BPC-157 and TB-500, separately or in a blend, for injury and soft-tissue recovery interests.", "search_blob": "wolverine stack wolverine-stack wolverine blend bpc-157 + tb-500 bpc tb stack wolverine peptide stack bpc/tb stack healing stack (bpc+tb) wolverine peptide blend bpc-157/tb-500 combo wolverine-stack wolverine stack wolverinestack wolverine blend bpc-157 + tb-500 bpc/tb stack injury tendon wolverine recovery pcac 503a compounding fda approved wolverine nasal bpc tb nasal nasal site pin flu-ish recovery injury repair joints & tendons soft-tissue healing performance continuity inflammation discussion post-strain bounce-back ligament / tendon irritation talk mobility continuity under training load injury tendon wolverine recovery nasal site pin flu-ish the wolverine stack combines bpc-157 and tb-500, separately or in a blend, for injury and soft-tissue recovery interests. accounts include pain-free training, little change and worsened nerve-burning symptoms; neither ingredient's contribution is isolated. wolverine stack is a community name for a peptide pair discussed for recovery. accounts include easier training, little change and worsened nerve symptoms, with rest and rehabilitation complicating attribution. pre-mixed vials hide the two different unit cultures (mcg vs mg). read both amounts. july 2026 pcac votes were on each peptide separately \u2014 not on a wolverine drug. healing stacks (named blends) peptide mixed mixed \u2014 local bpc and whole-body tb is a forum model, not established selective targeting. mixed local systemic", "legal_class": null }, { "id": 152, "slug": "glow-stack", "name": "GLOW stack", "aliases": [ "Glow blend", "GLOW peptide", "GHK-Cu BPC-157 TB-500", "glow stack 70mg", "GHK-Cu + BPC-157 + TB-500", "GLOW 5:1:1", "50/10/10 blend", "GHK BPC TB blend", "Glow 70", "GLOW 50", "GLOW 70", "5:1:1 blend" ], "type": "Peptide", "category": "Healing stacks (named blends)", "goals_use_cases": [ "recovery", "skin/hair", "injury repair", "anti-aging discussion", "soft-tissue healing", "collagen discussion", "post-procedure aesthetic recovery", "wound/scar remodeling talk" ], "delivery_methods": [ "subcutaneous", "pre-mixed multi-peptide vial" ], "discussion_popularity": "High", "reach": "Mixed", "misspellings_search_terms": [ "glow-stack", "glow stack", "glowstack", "Glow blend", "GLOW peptide", "GHK-Cu + BPC-157 + TB-500", "skin", "glow", "sting", "recovery", "copper uglies", "glow 50", "glow 70", "glow drip" ], "feel_search": [ "skin", "glow", "sting", "recovery", "copper uglies", "glow 50", "glow 70", "glow drip" ], "summary": "GLOW combines GHK-Cu, BPC-157 and TB-500; people discuss the blend for skin appearance and injury recovery.", "search_blob": "glow stack glow-stack glow blend glow peptide ghk-cu bpc-157 tb-500 glow stack 70mg ghk-cu + bpc-157 + tb-500 glow 5:1:1 50/10/10 blend ghk bpc tb blend glow 70 glow 50 glow 70 5:1:1 blend glow-stack glow stack glowstack glow blend glow peptide ghk-cu + bpc-157 + tb-500 skin glow sting recovery copper uglies glow 50 glow 70 glow drip recovery skin/hair injury repair anti-aging discussion soft-tissue healing collagen discussion post-procedure aesthetic recovery wound/scar remodeling talk skin glow sting recovery copper uglies glow 50 glow 70 glow drip glow combines ghk-cu, bpc-157 and tb-500; people discuss the blend for skin appearance and injury recovery. users describe possible skin or recovery changes over weeks, but injection sting, nausea or dizziness can be more noticeable. ingredients, schedules and other treatments vary between blends. glow combines ghk-cu, bpc-157 and a tb-500-labeled ingredient in varying ratios. reports include skin or recovery improvements, no benefit, painful injections, rash, nausea and dizziness; the blend prevents clear attribution to one component. total blend milligrams differ from each ingredient's amount. injection pain varies between reports. healing stacks (named blends) peptide mixed mixed \u2014 bpc may be near the complaint; tb and ghk are treated as whole-body. mixed local systemic", "legal_class": null }, { "id": 153, "slug": "klow-stack", "name": "KLOW stack", "aliases": [ "Klow blend", "KLOW peptide", "GLOW + KPV", "BPC TB GHK KPV", "klow 80mg", "BPC-157 TB-500 GHK-Cu KPV", "50/10/10/10 blend", "Hyper Recovery Stack (clinic nickname)", "CLO stack (misheard)", "KLOW 80", "5:1:1:1 blend" ], "type": "Peptide", "category": "Healing stacks (named blends)", "goals_use_cases": [ "recovery", "gut health", "inflammation discussion", "skin/hair", "injury repair", "soft-tissue healing", "post-procedure calm-down", "anti-aging / collagen talk", "systemic \u201cheal everything\u201d convenience stack" ], "delivery_methods": [ "subcutaneous", "pre-mixed multi-peptide vial" ], "discussion_popularity": "High", "reach": "Mixed", "misspellings_search_terms": [ "klow-stack", "klow stack", "klowstack", "Klow blend", "KLOW peptide", "GLOW + KPV", "gut", "inflammation", "klow", "skin", "copper uglies", "klow 80", "5:1:1:1" ], "feel_search": [ "gut", "inflammation", "klow", "skin", "copper uglies", "klow 80", "5:1:1:1" ], "summary": "KLOW is a four-peptide blend of GHK-Cu, BPC-157, TB-500 and KPV, discussed for skin, recovery and gut symptoms.", "search_blob": "klow stack klow-stack klow blend klow peptide glow + kpv bpc tb ghk kpv klow 80mg bpc-157 tb-500 ghk-cu kpv 50/10/10/10 blend hyper recovery stack (clinic nickname) clo stack (misheard) klow 80 5:1:1:1 blend klow-stack klow stack klowstack klow blend klow peptide glow + kpv gut inflammation klow skin copper uglies klow 80 5:1:1:1 recovery gut health inflammation discussion skin/hair injury repair soft-tissue healing post-procedure calm-down anti-aging / collagen talk systemic \u201cheal everything\u201d convenience stack gut inflammation klow skin copper uglies klow 80 5:1:1:1 klow is a four-peptide blend of ghk-cu, bpc-157, tb-500 and kpv, discussed for skin, recovery and gut symptoms. the reviewed reports range from extreme fatigue after two weeks to firmer-looking skin around week four. some favorable reports also involved collagen, topical skincare or a modified blend. klow combines ghk-cu, bpc-157, tb-500 and kpv. reports range from perceived skin or recovery benefits to no change, fatigue and injection-site reactions. four named ingredients share one fixed ratio in a premix; the label does not verify their identity, amount or sterility. healing stacks (named blends) peptide mixed mixed \u2014 the blend is whole-body once injected; some still pin the bpc portion near a complaint. mixed local systemic", "legal_class": null }, { "id": 154, "slug": "slu-pp-915", "name": "SLU-PP-915", "aliases": [ "SLU PP 915", "SLUPP915", "915 ERR agonist", "oral ERR pan-agonist", "915", "SLU-PP 915", "SLU-PP915", "oral ERR pan-agonist (915)", "compound 10s (boronic acid pan-ERR)" ], "type": "Non-peptide", "category": "Metabolic research compounds", "goals_use_cases": [ "endurance discussion", "fat loss", "metabolic health", "exercise-mimetic research", "performance", "fat loss / body recomposition (discussed)", "performance / aerobic capacity (preclinical)", "mitochondrial / oxidative capacity (discussed)", "oral alternative to SLU-PP-332 (community)", "heart-failure / cardiac metabolic research (preclinical)" ], "delivery_methods": [ "oral", "research injection in animal work" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "slu-pp-915", "slu pp 915", "slupp915", "915", "SLU-PP 915", "SLU-PP915", "endurance", "cardio", "exercise mimetic", "zone 2", "pre-workout", "10mg", "COA", "fasted cardio" ], "feel_search": [ "endurance", "cardio", "915", "exercise mimetic", "zone 2", "pre-workout", "fasted cardio" ], "summary": "SLU-PP-915 is an experimental oral small molecule studied for endurance by activating estrogen-related receptors; it is chemically distinct from SLU-PP-332.", "search_blob": "slu-pp-915 slu-pp-915 slu pp 915 slupp915 915 err agonist oral err pan-agonist 915 slu-pp 915 slu-pp915 oral err pan-agonist (915) compound 10s (boronic acid pan-err) slu-pp-915 slu pp 915 slupp915 915 slu-pp 915 slu-pp915 endurance cardio exercise mimetic zone 2 pre-workout 10mg coa fasted cardio endurance discussion fat loss metabolic health exercise-mimetic research performance fat loss / body recomposition (discussed) performance / aerobic capacity (preclinical) mitochondrial / oxidative capacity (discussed) oral alternative to slu-pp-332 (community) heart-failure / cardiac metabolic research (preclinical) endurance cardio 915 exercise mimetic zone 2 pre-workout fasted cardio slu-pp-915 is an experimental oral small molecule studied for endurance by activating estrogen-related receptors; it is chemically distinct from slu-pp-332. reports include energy, little change, reflux and later exhaustion. some endurance/focus and slower-recovery reports involve uncertain slu identity and cannot be assigned to this compound. slu-pp-915 is an experimental oral compound discussed for endurance. zone-2 accounts include easier cardio, no change and later exhaustion; some apparent successes involve uncertain or mislabeled products. some people say 2 mg is already high; others want 20\u2013100 mg. 2026 x polls split 1 mg vs 10 mg vs 20 mg. no consensus. metabolic research compounds non-peptide systemic systemic \u2014 pan-err small molecule (err\u03b1/\u03b2/\u03b3) aimed at aerobic/exercise-mimetic gene programs in muscle, heart, and other high-energy tissues. systemic whole-body circulating", "legal_class": null }, { "id": 155, "slug": "hgh-somatropin", "name": "HGH (Somatropin)", "aliases": [ "Human Growth Hormone", "somatropin", "GH", "rhGH" ], "type": "Peptide", "category": "Growth hormone axis", "goals_use_cases": [ "muscle growth", "fat loss", "recovery", "longevity" ], "delivery_methods": [ "subcutaneous", "intramuscular" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "hgh-somatropin", "hgh somatropin", "hghsomatropin", "HGH (Somatropin)", "hgh-(somatropin)", "Human Growth Hormone", "hgh", "somatropin", "water retention", "carpal", "191aa", "kits", "IGF-1", "split dose", "empty stomach" ], "feel_search": [ "hgh", "somatropin", "water retention", "carpal", "191aa", "kits", "IGF-1", "split dose", "empty stomach" ], "summary": "Somatropin is recombinant human growth hormone\u2014the same molecule covered under HGH, discussed for replacement therapy, recovery and physique changes.", "search_blob": "hgh (somatropin) hgh-somatropin human growth hormone somatropin gh rhgh hgh-somatropin hgh somatropin hghsomatropin hgh (somatropin) hgh-(somatropin) human growth hormone hgh somatropin water retention carpal 191aa kits igf-1 split dose empty stomach muscle growth fat loss recovery longevity hgh somatropin water retention carpal 191aa kits igf-1 split dose empty stomach somatropin is recombinant human growth hormone\u2014the same molecule covered under hgh, discussed for replacement therapy, recovery and physique changes. some notice little immediately; others report puffiness, tight rings, hand tingling, fatigue or sleep changes. appearance and recovery claims are usually assessed over longer periods. somatropin is manufactured human growth hormone, also called hgh. people discuss sleep, recovery and physique changes; reports include little benefit, swelling, numb hands and fatigue. gray-market iu claims are unreliable. legal status is part of the card. growth hormone axis peptide systemic systemic gh replacement / abuse context. systemic whole-body circulating", "legal_class": null }, { "id": 156, "slug": "hgh-fragment-176-191", "name": "HGH Fragment 176-191", "aliases": [ "Frag 176-191", "HGH Frag", "fragment 176", "Fragment 176-191", "hGH Frag", "HGH Fragment 176-191", "frag-176-191", "hGH Fragment 176-191", "GH Frag 176-191", "hGH 176-191", "Growth hormone fragment 176-191", "C-terminal hGH fragment (community label)", "hGH frag 176\u2013191", "HGH Frag 176-191" ], "type": "Peptide", "category": "Metabolic / fat-loss peptides", "goals_use_cases": [ "fat loss", "performance", "recovery" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "hgh-fragment-176-191", "hgh fragment 176 191", "hghfragment176191", "HGH Fragment 176-191", "Frag 176-191", "HGH Frag", "frag 176 191", "frag176191", "fat loss", "fasted", "cut", "fragment" ], "feel_search": [ "fat loss", "fasted", "cut", "fragment" ], "summary": "HGH fragment 176\u2013191 is a short growth-hormone fragment marketed for fat loss; it is not full-length HGH or automatically interchangeable with AOD-9604.", "search_blob": "hgh fragment 176-191 hgh-fragment-176-191 frag 176-191 hgh frag fragment 176 fragment 176-191 hgh frag hgh fragment 176-191 frag-176-191 hgh fragment 176-191 gh frag 176-191 hgh 176-191 growth hormone fragment 176-191 c-terminal hgh fragment (community label) hgh frag 176\u2013191 hgh frag 176-191 hgh-fragment-176-191 hgh fragment 176 191 hghfragment176191 hgh fragment 176-191 frag 176-191 hgh frag frag 176 191 frag176191 fat loss fasted cut fragment fat loss performance recovery fat loss fasted cut fragment hgh fragment 176\u2013191 is a short growth-hormone fragment marketed for fat loss; it is not full-length hgh or automatically interchangeable with aod-9604. there is no clear immediate sensation in the reviewed report. its fat-loss claim involved fasting and cardio, so it does not show what the fragment contributed. hgh fragment 176-191 is modeled on the tail end of human growth hormone. fat-loss reports conflict and are often confounded by diet, training or other drugs. morning fasting and bedtime use recur in discussion, but food-window claims are unvalidated and aod-9604 is a distinct sequence. metabolic / fat-loss peptides peptide systemic systemic fat-loss fragment peptide lore. systemic whole-body circulating", "legal_class": null }, { "id": 157, "slug": "liraglutide", "name": "Liraglutide", "aliases": [ "Victoza", "Saxenda", "lira" ], "type": "Peptide", "category": "Metabolic / GLP-1 class", "goals_use_cases": [ "fat loss", "appetite suppression", "insulin sensitivity", "cardiovascular" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "liraglutide", "Victoza", "Saxenda", "lira", "liraglutide peptide", "liraglutide dosage", "fat loss", "appetite suppression", "insulin sensitivity", "cardiovascular" ], "feel_search": [ "fat loss", "appetite suppression", "insulin sensitivity", "cardiovascular" ], "summary": "Liraglutide is a once-daily injectable GLP-1 receptor agonist used in diabetes and weight management, sold under brands including Victoza and Saxenda.", "search_blob": "liraglutide liraglutide victoza saxenda lira liraglutide victoza saxenda lira liraglutide peptide liraglutide dosage fat loss appetite suppression insulin sensitivity cardiovascular fat loss appetite suppression insulin sensitivity cardiovascular fat loss appetite suppression insulin sensitivity cardiovascular liraglutide is a once-daily injectable glp-1 receptor agonist used in diabetes and weight management, sold under brands including victoza and saxenda. appetite can change early, but nausea and sleep disruption may dominate. in the reviewed timing thread, some preferred evenings while one switched to mornings because insomnia outweighed the nausea. liraglutide is a daily injectable medicine used in diabetes and weight management. some report earlier fullness or quieter appetite; others notice little benefit or experience nausea, fatigue and constipation. metabolic / glp-1 class peptide systemic systemic \u2014 whole-body glp-1 effects on appetite, gastric emptying, and glycemic control. systemic whole-body circulating", "legal_class": null }, { "id": 158, "slug": "mgf-peg-mgf", "name": "MGF / PEG-MGF", "aliases": [ "Mechano Growth Factor", "PEGylated MGF", "IGF-1Ec" ], "type": "Peptide", "category": "Growth factors / muscle", "goals_use_cases": [ "muscle growth", "recovery", "injury repair" ], "delivery_methods": [ "intramuscular", "subcutaneous" ], "discussion_popularity": "Medium", "reach": "Mixed", "misspellings_search_terms": [ "mgf-peg-mgf", "mgf peg mgf", "mgfpegmgf", "MGF / PEG-MGF", "mgf-/-peg-mgf", "Mechano Growth Factor", "muscle growth", "recovery", "injury repair" ], "feel_search": [ "muscle growth", "recovery", "injury repair" ], "summary": "MGF/PEG-MGF is an umbrella for synthetic IGF-1 E-domain peptides sold for local muscle recovery; PEG modification changes the product.", "search_blob": "mgf / peg-mgf mgf-peg-mgf mechano growth factor pegylated mgf igf-1ec mgf-peg-mgf mgf peg mgf mgfpegmgf mgf / peg-mgf mgf-/-peg-mgf mechano growth factor muscle growth recovery injury repair muscle growth recovery injury repair muscle growth recovery injury repair mgf/peg-mgf is an umbrella for synthetic igf-1 e-domain peptides sold for local muscle recovery; peg modification changes the product. reports range from immediate fullness to injection pain or no noticeable effect. older stacked logs cannot isolate mgf from peg-mgf or accompanying igf. mgf and peg-mgf are different synthetic peptides discussed for muscle recovery. reports include fullness, less soreness, painful injections and no benefit; they do not establish new muscle growth. growth factors / muscle peptide mixed mixed \u2014 local/systemic igf-splice variant research chem culture. mixed local systemic", "legal_class": null }, { "id": 159, "slug": "dasatinib-quercetin", "name": "Dasatinib + Quercetin", "aliases": [ "D+Q", "D plus Q senolytic", "Sprycel + quercetin" ], "type": "Non-peptide", "category": "Longevity & cellular energy", "goals_use_cases": [ "longevity", "recovery", "bone health", "cognition" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "dasatinib-quercetin", "dasatinib quercetin", "dasatinibquercetin", "Dasatinib + Quercetin", "dasatinib-+-quercetin", "D+Q", "longevity", "recovery", "bone health", "cognition" ], "feel_search": [ "longevity", "recovery", "bone health", "cognition" ], "summary": "D+Q combines the leukemia drug dasatinib with the flavonoid quercetin in experimental research targeting senescent cells.", "search_blob": "dasatinib + quercetin dasatinib-quercetin d+q d plus q senolytic sprycel + quercetin dasatinib-quercetin dasatinib quercetin dasatinibquercetin dasatinib + quercetin dasatinib-+-quercetin d+q longevity recovery bone health cognition longevity recovery bone health cognition longevity recovery bone health cognition d+q combines the leukemia drug dasatinib with the flavonoid quercetin in experimental research targeting senescent cells. one long-term user reports no noticeable effect; another credits a rapamycin/d+q stack with better joints and activity. neither observation isolates the combination\u2019s mechanism. d+q combines dasatinib and quercetin in experimental senolytic use. reports range from no change to stack-confounded improvement or several days of feeling unwell. longevity & cellular energy non-peptide systemic systemic intermittent senolytic drug+polyphenol combo. systemic whole-body circulating", "legal_class": null }, { "id": 160, "slug": "glynac", "name": "GlyNAC", "aliases": [ "Glycine + NAC", "glycine N-acetylcysteine" ], "type": "Non-peptide", "category": "Longevity & cellular energy", "goals_use_cases": [ "longevity", "energy", "recovery" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "glynac", "Glycine + NAC", "glycine N-acetylcysteine", "glynac peptide", "glynac dosage", "GlyNAC dose", "longevity", "energy", "recovery" ], "feel_search": [ "longevity", "energy", "recovery" ], "summary": "GlyNAC is the combination of glycine and N-acetylcysteine, discussed for glutathione support, aging-related health and recovery.", "search_blob": "glynac glynac glycine + nac glycine n-acetylcysteine glynac glycine + nac glycine n-acetylcysteine glynac peptide glynac dosage glynac dose longevity energy recovery longevity energy recovery longevity energy recovery glynac is the combination of glycine and n-acetylcysteine, discussed for glutathione support, aging-related health and recovery. responses range from gi discomfort or lightheadedness to better or worse sleep. the first-night reports conflict, so neither component nor an ideal time of day can be inferred from them. glynac combines oral glycine and nac. reports range from better energy or recovery to no noticeable change, dizziness, stomach trouble and either better or worse sleep. two common supplements co-taken. longevity & cellular energy non-peptide systemic systemic \u2014 oral glycine and nac supply precursors for glutathione (gsh), an antioxidant made by the body; this does not establish benefit in every tissue or person. systemic whole-body circulating", "legal_class": null }, { "id": 161, "slug": "akg", "name": "Alpha-Ketoglutarate (AKG)", "aliases": [ "Ca-AKG", "calcium alpha-ketoglutarate" ], "type": "Non-peptide", "category": "Longevity & cellular energy", "goals_use_cases": [ "longevity", "recovery", "bone health" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "akg", "Alpha-Ketoglutarate (AKG)", "alpha-ketoglutarate-(akg)", "Ca-AKG", "calcium alpha-ketoglutarate", "akg peptide", "longevity", "recovery", "bone health" ], "feel_search": [ "longevity", "recovery", "bone health" ], "summary": "Alpha-ketoglutarate (AKG) is a normal energy-metabolism compound sold in several supplement forms for longevity and exercise interest.", "search_blob": "alpha-ketoglutarate (akg) akg ca-akg calcium alpha-ketoglutarate akg alpha-ketoglutarate (akg) alpha-ketoglutarate-(akg) ca-akg calcium alpha-ketoglutarate akg peptide longevity recovery bone health longevity recovery bone health longevity recovery bone health alpha-ketoglutarate (akg) is a normal energy-metabolism compound sold in several supplement forms for longevity and exercise interest. reports range from subtle running benefits to no observable change over months or years. different akg salts and supplement stacks complicate comparisons. akg is a compound the body uses in energy metabolism, sold in several oral supplement forms. reports range from subtle exercise benefits to no change over months or years, with stomach or bladder irritation in some accounts. longevity & cellular energy non-peptide systemic systemic metabolic intermediate supplement. systemic whole-body circulating", "legal_class": null }, { "id": 162, "slug": "acarbose", "name": "Acarbose", "aliases": [ "Precose", "Glucobay" ], "type": "Non-peptide", "category": "Longevity & cellular energy", "goals_use_cases": [ "longevity", "insulin sensitivity" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Mixed", "misspellings_search_terms": [ "acarbose", "Precose", "Glucobay", "acarbose peptide", "acarbose dosage", "Acarbose dose", "longevity", "insulin sensitivity" ], "feel_search": [ "longevity", "insulin sensitivity" ], "summary": "Acarbose is a tablet that slows carbohydrate digestion to reduce after-meal glucose rises; biohackers also discuss it for longevity.", "search_blob": "acarbose acarbose precose glucobay acarbose precose glucobay acarbose peptide acarbose dosage acarbose dose longevity insulin sensitivity longevity insulin sensitivity longevity insulin sensitivity acarbose is a tablet that slows carbohydrate digestion to reduce after-meal glucose rises; biohackers also discuss it for longevity. gas and bloating may be more noticeable than glucose changes. in one log, some meals felt uneventful while a ramen-and-vegetable meal brought hours of gas. acarbose is an oral medicine that slows carbohydrate digestion and reduces after-meal glucose rises. gut discomfort can be more noticeable than benefit; mouse longevity findings do not establish human lifespan extension. longevity & cellular energy non-peptide mixed mixed \u2014 primarily gut-local enzyme block with systemic glucose effects. mixed local systemic", "legal_class": null }, { "id": 163, "slug": "selegiline", "name": "Selegiline (Deprenyl)", "aliases": [ "Deprenyl", "Eldepryl", "Emsam", "l-deprenyl" ], "type": "Non-peptide", "category": "Longevity & cellular energy", "goals_use_cases": [ "longevity", "mood", "cognition" ], "delivery_methods": [ "oral", "sublingual" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "selegiline", "Selegiline (Deprenyl)", "selegiline-(deprenyl)", "Deprenyl", "Eldepryl", "Emsam", "longevity", "mood", "cognition" ], "feel_search": [ "longevity", "mood", "cognition" ], "summary": "Selegiline, or deprenyl, is a monoamine oxidase inhibitor used in Parkinson's treatment and, as a patch, for depression. Nootropic and longevity discussion concerns separate goals.", "search_blob": "selegiline (deprenyl) selegiline deprenyl eldepryl emsam l-deprenyl selegiline selegiline (deprenyl) selegiline-(deprenyl) deprenyl eldepryl emsam longevity mood cognition longevity mood cognition longevity mood cognition selegiline, or deprenyl, is a monoamine oxidase inhibitor used in parkinson's treatment and, as a patch, for depression. nootropic and longevity discussion concerns separate goals. one commenter described a subtle mental lift that faded with repeated use; another described difficult symptoms after missed doses and stopping. selegiline is a prescription drug with swallowed, orally disintegrating and patch forms. reports include improved mood or motivation, little benefit, fading effects, headache and persistent insomnia. longevity & cellular energy non-peptide systemic systemic \u2014 irreversible monoamine oxidase inhibitor; preference for the b enzyme form depends on exposure and formulation. systemic whole-body circulating", "legal_class": null }, { "id": 164, "slug": "low-dose-naltrexone", "name": "Low-Dose Naltrexone", "aliases": [ "LDN", "naltrexone low dose" ], "type": "Non-peptide", "category": "Immune / antimicrobial", "goals_use_cases": [ "recovery", "immune", "mood", "gut health" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "low-dose-naltrexone", "low dose naltrexone", "lowdosenaltrexone", "Low-Dose Naltrexone", "LDN", "naltrexone low dose", "recovery", "immune", "mood", "gut health" ], "feel_search": [ "recovery", "immune", "mood", "gut health" ], "summary": "Low-dose naltrexone (LDN) is an opioid-receptor-blocking medicine used off label for conditions such as chronic pain; it is the same substance as the LDN entry.", "search_blob": "low-dose naltrexone low-dose-naltrexone ldn naltrexone low dose low-dose-naltrexone low dose naltrexone lowdosenaltrexone low-dose naltrexone ldn naltrexone low dose recovery immune mood gut health recovery immune mood gut health recovery immune mood gut health low-dose naltrexone (ldn) is an opioid-receptor-blocking medicine used off label for conditions such as chronic pain; it is the same substance as the ldn entry. early grogginess, gi discomfort and sleep changes vary widely. some report encouraging days, but a detailed longer diary ended with no net benefit after months. low-dose naltrexone is an oral compound people look up for recovery. discussed for immune modulation, pain, and autoimmune lore \u2014 distinct from full-dose addiction dosing. immune / antimicrobial non-peptide systemic systemic low-dose opioid antagonist immunomodulation lore. systemic whole-body circulating", "legal_class": null }, { "id": 165, "slug": "yk-11", "name": "YK-11", "aliases": [ "YK11", "myostatin SARM", "myostatin-related SARM discussion", "YK-11", "ykl-11", "YK 11", "Myostine (research-commerce / Health Canada nickname)", "Myobol (forum/vendor nickname)", "(17\u03b1,20E)-17,20-[(1-methoxyethylidene)bis(oxy)]-3-oxo-19-norpregna-4,20-diene-21-carboxylic acid methyl ester" ], "type": "Non-peptide", "category": "Performance / endurance", "goals_use_cases": [ "muscle growth", "performance" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "yk-11", "yk 11", "yk11", "myostatin SARM", "yk-11 peptide", "yk-11 dosage", "ykl 11", "ykl11", "YK-11", "YK11", "YK 11", "muscle growth", "performance" ], "feel_search": [ "muscle growth", "performance" ], "summary": "YK-11 is a steroidal SARM-like research compound discussed for muscle and myostatin-related effects.", "search_blob": "yk-11 yk-11 yk11 myostatin sarm myostatin-related sarm discussion yk-11 ykl-11 yk 11 myostine (research-commerce / health canada nickname) myobol (forum/vendor nickname) (17\u03b1,20e)-17,20-[(1-methoxyethylidene)bis(oxy)]-3-oxo-19-norpregna-4,20-diene-21-carboxylic acid methyl ester yk-11 yk 11 yk11 myostatin sarm yk-11 peptide yk-11 dosage ykl 11 ykl11 yk-11 yk11 yk 11 muscle growth performance muscle growth performance muscle growth performance yk-11 is a steroidal sarm-like research compound discussed for muscle and myostatin-related effects. one user reported size and strength gains alongside joint pain, acne, hair loss and lower libido; returning to training confounded the gains. yk-11 is a steroidal androgen-receptor research compound. reports range from appearance or strength changes to little benefit, joint pain and hormonal symptoms. human rcts are not the foundation \u2014 mostly community + limited preclinical framing. performance / endurance non-peptide systemic systemic myostatin-pathway research chem. systemic whole-body circulating", "legal_class": null }, { "id": 166, "slug": "s-4-andarine", "name": "S-4 (Andarine)", "aliases": [ "Andarine", "S4", "GTx-007" ], "type": "Non-peptide", "category": "Performance / endurance", "goals_use_cases": [ "fat loss", "muscle growth", "performance" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "s-4-andarine", "s 4 andarine", "s4andarine", "S-4 (Andarine)", "s-4-(andarine)", "Andarine", "fat loss", "muscle growth", "performance" ], "feel_search": [ "fat loss", "muscle growth", "performance" ], "summary": "Andarine (S-4) is a research SARM discussed for cutting and muscle retention, with distinctive visual-disturbance reports.", "search_blob": "s-4 (andarine) s-4-andarine andarine s4 gtx-007 s-4-andarine s 4 andarine s4andarine s-4 (andarine) s-4-(andarine) andarine fat loss muscle growth performance fat loss muscle growth performance fat loss muscle growth performance andarine (s-4) is a research sarm discussed for cutting and muscle retention, with distinctive visual-disturbance reports. one user described intermittent yellowish vision that persisted on missed-dose days; they were also taking sr9009. andarine is an oral research sarm. s-4 reports include strength or appearance changes, absent expected fat loss and sometimes serious visual disturbances. performance / endurance non-peptide systemic systemic sarm research chem. systemic whole-body circulating", "legal_class": null }, { "id": 167, "slug": "s-23", "name": "S-23", "aliases": [ "S23", "S 23", "S23 SARM", "S-23", "s23", "S-23 SARM", "Mastorin (informal / research-chem trade discussion)", "Ultrabolic (branded research-chem label discussed in forums)", "(S)-N-(4-cyano-3-trifluoromethylphenyl)-3-(3-fluoro-4-chlorophenoxy)-2-hydroxy-2-methylpropanamide" ], "type": "Non-peptide", "category": "Performance / endurance", "goals_use_cases": [ "muscle growth", "fat loss", "performance" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "s-23", "s 23", "s-23 peptide", "s-23 dosage", "S-23 dose", "S-23", "S-23 SARM", "S23 SARM", "S 23", "Mastorin (informal / research-chem trade discussion)", "muscle growth", "fat loss", "performance" ], "feel_search": [ "muscle growth", "fat loss", "performance" ], "summary": "S-23 is a nonsteroidal research SARM discussed for muscle and body recomposition, with substantial hormone-suppression concerns.", "search_blob": "s-23 s-23 s23 s 23 s23 sarm s-23 s23 s-23 sarm mastorin (informal / research-chem trade discussion) ultrabolic (branded research-chem label discussed in forums) (s)-n-(4-cyano-3-trifluoromethylphenyl)-3-(3-fluoro-4-chlorophenoxy)-2-hydroxy-2-methylpropanamide s-23 s 23 s-23 peptide s-23 dosage s-23 dose s-23 s-23 sarm s23 sarm s 23 mastorin (informal / research-chem trade discussion) muscle growth fat loss performance muscle growth fat loss performance muscle growth fat loss performance s-23 is a nonsteroidal research sarm discussed for muscle and body recomposition, with substantial hormone-suppression concerns. one stacked-cycle user described stronger training drive, aggression and libido, but an unpleasant period after stopping. s-23 is a hormone-active research sarm discussed for strength and a leaner appearance. reports also include hair shedding, poor sleep, anger, cramps and hormone-suppression concerns, often during combined drug use. performance / endurance non-peptide systemic systemic sarm research chem. systemic whole-body circulating", "legal_class": null }, { "id": 168, "slug": "aicar", "name": "AICAR", "aliases": [ "Acadesine", "5-aminoimidazole-4-carboxamide riboside" ], "type": "Non-peptide", "category": "Performance / endurance", "goals_use_cases": [ "performance", "fat loss", "insulin sensitivity" ], "delivery_methods": [ "subcutaneous", "intramuscular" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "aicar", "AICA ribonucleotide", "Acadesine", "5-aminoimidazole-4-carboxamide riboside", "aicar peptide", "aicar dosage", "performance", "fat loss", "insulin sensitivity" ], "feel_search": [ "performance", "fat loss", "insulin sensitivity" ], "summary": "AICAR (acadesine) is a non-peptide nucleoside studied for metabolic signaling and discussed as an endurance aid.", "search_blob": "aicar aicar acadesine 5-aminoimidazole-4-carboxamide riboside aicar aica ribonucleotide acadesine 5-aminoimidazole-4-carboxamide riboside aicar peptide aicar dosage performance fat loss insulin sensitivity performance fat loss insulin sensitivity performance fat loss insulin sensitivity aicar (acadesine) is a non-peptide nucleoside studied for metabolic signaling and discussed as an endurance aid. the inspected stacked-use log reports little overall difference and credits its speedy, hot feeling to helios. it does not isolate aicar's effects. aicar/acadesine is a non-peptide metabolic research compound. accounts include easier cardio, little change and poor tolerance, often with other drugs. low oral-solution exposure in one human study does not establish pill performance; unverified products and co-use complicate reported results. performance / endurance non-peptide systemic systemic ampk research tool. systemic whole-body circulating", "legal_class": null }, { "id": 169, "slug": "bimagrumab", "name": "Bimagrumab", "aliases": [ "BYM338", "bima" ], "type": "Non-peptide", "category": "Growth factors / muscle", "goals_use_cases": [ "muscle growth", "fat loss" ], "delivery_methods": [ "IV", "subcutaneous" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "bimagrumab", "BYM338", "bima", "bimagrumab peptide", "bimagrumab dosage", "Bimagrumab dose", "muscle growth", "fat loss" ], "feel_search": [ "muscle growth", "fat loss" ], "summary": "Bimagrumab is an investigational activin-receptor antibody studied for muscle mass and metabolic outcomes.", "search_blob": "bimagrumab bimagrumab bym338 bima bimagrumab bym338 bima bimagrumab peptide bimagrumab dosage bimagrumab dose muscle growth fat loss muscle growth fat loss muscle growth fat loss bimagrumab is an investigational activin-receptor antibody studied for muscle mass and metabolic outcomes. modern forum threads here ask about access and expectations. a separate historical trial participant described easier hand tasks, little walking improvement and diarrhea, without establishing a predictable treatment response. bimagrumab is an investigational antibody studied for body composition. modern forums mostly express expectations; a historical trial participant described easier hand tasks, little walking improvement and diarrhea. growth factors / muscle non-peptide systemic systemic antibody against activin receptor pathway. systemic whole-body circulating", "legal_class": null }, { "id": 170, "slug": "ace-031", "name": "ACE-031", "aliases": [ "ActRIIB-Fc", "ACE031", "Ramatercept (related)" ], "type": "Peptide", "category": "Growth factors / muscle", "goals_use_cases": [ "muscle growth", "performance", "bone health" ], "delivery_methods": [ "subcutaneous", "intramuscular" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "ace-031", "ace 031", "ace031", "ActRIIB-Fc", "Ramatercept (related)", "ace-031 peptide", "muscle growth", "performance", "bone health" ], "feel_search": [ "muscle growth", "performance", "bone health" ], "summary": "ACE-031 is a soluble activin-receptor decoy studied for muscle growth; its clinical development stopped after safety concerns.", "search_blob": "ace-031 ace-031 actriib-fc ace031 ramatercept (related) ace-031 ace 031 ace031 actriib-fc ramatercept (related) ace-031 peptide muscle growth performance bone health muscle growth performance bone health muscle growth performance bone health ace-031 is a soluble activin-receptor decoy studied for muscle growth; its clinical development stopped after safety concerns. an early forum account describes more sweating and a stronger pump without added strength. product identity and other compounds limit what that shows. ace-031 is an experimental activin-receptor decoy protein discussed for muscle growth. reports include pumps without added strength and gains during large stacks; clinical development ended after safety concerns. growth factors / muscle peptide systemic systemic activin-pathway biologic (discontinued development). systemic whole-body circulating", "legal_class": null }, { "id": 171, "slug": "b7-33", "name": "B7-33", "aliases": [ "B7-33 relaxin analog", "H2 relaxin derivative" ], "type": "Peptide", "category": "Healing & repair", "goals_use_cases": [ "anti fibrotic", "cardiovascular", "recovery" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "b7-33", "b7 33", "b733", "B7-33 relaxin analog", "H2 relaxin derivative", "b7-33 peptide", "anti fibrotic", "cardiovascular", "recovery" ], "feel_search": [ "anti fibrotic", "cardiovascular", "recovery" ], "summary": "B7-33 is a synthetic relaxin-family peptide studied for signals involved in tissue scarring; it is not an organ-specific peptide extract.", "search_blob": "b7-33 b7-33 b7-33 relaxin analog h2 relaxin derivative b7-33 b7 33 b733 b7-33 relaxin analog h2 relaxin derivative b7-33 peptide anti fibrotic cardiovascular recovery anti fibrotic cardiovascular recovery anti fibrotic cardiovascular recovery b7-33 is a synthetic relaxin-family peptide studied for signals involved in tissue scarring; it is not an organ-specific peptide extract. a user combining b7-33 with bpc/tb reports early body sensations and easier exercise. their explanation of clearing tissue is unverified. b7-33 is an experimental relaxin-family peptide discussed for scarring. one combined-use account reports easier exercise without establishing scar removal. healing & repair peptide systemic systemic research peptide \u2014 relaxin-family/rxfp1 signaling, not an organ bioregulator or a proven local scar treatment. systemic whole-body circulating", "legal_class": null }, { "id": 172, "slug": "thymulin", "name": "Thymulin", "aliases": [ "thymic factor", "FTS-Zn", "facteur thymique s\u00e9rique" ], "type": "Peptide", "category": "Immune / antimicrobial", "goals_use_cases": [ "immune", "recovery", "longevity" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "thymulin", "thymic factor", "FTS-Zn", "facteur thymique s\u00e9rique", "thymulin peptide", "thymulin dosage", "immune", "recovery", "longevity" ], "feel_search": [ "immune", "recovery", "longevity" ], "summary": "Thymulin is a nine-amino-acid thymus hormone that depends on zinc, discussed for immune regulation; it differs from the multi-peptide extract Thymalin.", "search_blob": "thymulin thymulin thymic factor fts-zn facteur thymique s\u00e9rique thymulin thymic factor fts-zn facteur thymique s\u00e9rique thymulin peptide thymulin dosage immune recovery longevity immune recovery longevity immune recovery longevity thymulin is a nine-amino-acid thymus hormone that depends on zinc, discussed for immune regulation; it differs from the multi-peptide extract thymalin. one multi-peptide user initially credited symptom relief, then reported gut problems and withdrew confidence that the peptides had helped. thymulin is a zinc-dependent thymus peptide. reports include sleep/energy changes, null outcomes and an immune-benefit claim later withdrawn after gut problems, with substantial product-identity uncertainty. immune / antimicrobial peptide systemic systemic thymic-hormone discussion around a defined zinc-dependent nonapeptide; product naming is unusually error-prone. systemic whole-body circulating", "legal_class": null }, { "id": 173, "slug": "endoluten", "name": "Endoluten", "aliases": [ "Endoluten pineal bioregulator", "pineal gland peptide complex" ], "type": "Peptide", "category": "Organ bioregulators", "goals_use_cases": [ "sleep", "longevity", "hormone support" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "endoluten", "Endoluten pineal bioregulator", "pineal gland peptide complex", "endoluten peptide", "endoluten dosage", "Endoluten dose", "sleep", "longevity", "hormone support" ], "feel_search": [ "sleep", "longevity", "hormone support" ], "summary": "Endoluten is an oral peptide complex from young-animal pineal tissue, marketed as a bioregulator for sleep and longevity.", "search_blob": "endoluten endoluten endoluten pineal bioregulator pineal gland peptide complex endoluten endoluten pineal bioregulator pineal gland peptide complex endoluten peptide endoluten dosage endoluten dose sleep longevity hormone support sleep longevity hormone support sleep longevity hormone support endoluten is an oral peptide complex from young-animal pineal tissue, marketed as a bioregulator for sleep and longevity. a ten-day diary describes sleepiness, calm and less mental chatter, but reduced sexual arousal and no lucid dream by day ten. endoluten is an oral animal-pineal peptide complex discussed for sleep and calm. reports include better sleep, no lucid-dream benefit and opposite changes in sexual interest; it is distinct from synthetic epithalon. organ bioregulators peptide systemic oral animal-pineal peptide complex marketed as a pineal bioregulator; systemic benefit, composition equivalence, and human efficacy remain uncertain. systemic whole-body circulating", "legal_class": null }, { "id": 174, "slug": "pancragen", "name": "Pancragen", "aliases": [ "Pancragen peptide", "pancreas bioregulator", "KEDW tetrapeptide" ], "type": "Peptide", "category": "Organ bioregulators", "goals_use_cases": [ "insulin sensitivity", "longevity", "energy", "hormone support" ], "delivery_methods": [ "subcutaneous", "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "pancragen", "Pancragen peptide", "pancreas bioregulator", "KEDW tetrapeptide", "pancragen dosage", "Pancragen dose", "insulin sensitivity", "longevity", "energy", "hormone support" ], "feel_search": [ "insulin sensitivity", "longevity", "energy", "hormone support" ], "summary": "Pancragen is a short synthetic peptide sold as a pancreas bioregulator for metabolic support; brand extracts may contain different material.", "search_blob": "pancragen pancragen pancragen peptide pancreas bioregulator kedw tetrapeptide pancragen pancragen peptide pancreas bioregulator kedw tetrapeptide pancragen dosage pancragen dose insulin sensitivity longevity energy hormone support insulin sensitivity longevity energy hormone support insulin sensitivity longevity energy hormone support pancragen is a short synthetic peptide sold as a pancreas bioregulator for metabolic support; brand extracts may contain different material. there is too little detailed reporting to describe a typical feel. one user perceived better glucose after a week but supplied no readings, route or later follow-up. pancragen is a synthetic peptide discussed for pancreatic support. one user perceived better glucose; another stopped after severe burning. neither account defines a typical response. organ bioregulators peptide systemic marketed for pancreatic support; oral and injectable preparations do not establish selective organ delivery or equivalent exposure. systemic whole-body circulating", "legal_class": null }, { "id": 175, "slug": "thyreogen", "name": "Thyreogen", "aliases": [ "Thyreogen peptide", "thyroid bioregulator" ], "type": "Peptide", "category": "Organ bioregulators", "goals_use_cases": [ "hormone support", "energy", "longevity" ], "delivery_methods": [ "oral", "subcutaneous" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "thyreogen", "Thyreogen peptide", "thyroid bioregulator", "thyreogen dosage", "Thyreogen dose", "thyreogen research", "hormone support", "energy", "longevity" ], "feel_search": [ "hormone support", "energy", "longevity" ], "summary": "Thyreogen (A-2) is a thyroid-tissue-derived mixture of peptide fractions marketed for thyroid support.", "search_blob": "thyreogen thyreogen thyreogen peptide thyroid bioregulator thyreogen thyreogen peptide thyroid bioregulator thyreogen dosage thyreogen dose thyreogen research hormone support energy longevity hormone support energy longevity hormone support energy longevity thyreogen (a-2) is a thyroid-tissue-derived mixture of peptide fractions marketed for thyroid support. one capsule user noticed no benefit; another described better energy while also using thyroid replacement and several other interventions. thyreogen is an oral thyroid-tissue peptide mixture. accounts include no felt benefit and perceived energy or weight improvement with other treatments; lower antibodies do not establish restored thyroid function. organ bioregulators peptide systemic oral thyroid-tissue peptide mixture marketed for thyroid support; organ-focused claims remain vendor-led. systemic whole-body circulating", "legal_class": null }, { "id": 176, "slug": "cortexin", "name": "Cortexin", "aliases": [ "Cortexin lyophilisate", "cattle-brain polypeptides" ], "type": "Peptide", "category": "Cognitive / nootropic peptides", "goals_use_cases": [ "cognition", "memory", "focus", "mood" ], "delivery_methods": [ "intramuscular" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "cortexin", "Cortexin lyophilisate", "cattle-brain polypeptides", "cortexin peptide", "cortexin dosage", "Cortexin dose", "cognition", "memory", "focus", "mood" ], "feel_search": [ "cognition", "memory", "focus", "mood" ], "summary": "Cortexin is an animal-brain-derived mixture of peptide fractions supplied for intramuscular injection, distinct from the single peptide Cortagen.", "search_blob": "cortexin cortexin cortexin lyophilisate cattle-brain polypeptides cortexin cortexin lyophilisate cattle-brain polypeptides cortexin peptide cortexin dosage cortexin dose cognition memory focus mood cognition memory focus mood cognition memory focus mood cortexin is an animal-brain-derived mixture of peptide fractions supplied for intramuscular injection, distinct from the single peptide cortagen. one user reports better everyday short-term memory after a course; another describes alertness and work recall building across repeated injections. cortexin is an animal-brain-derived peptide mixture supplied for intramuscular injection. reports range from better everyday recall or calmer focus to brain fog, overstimulation and emotional flatness; persistence is disputed. cognitive / nootropic peptides peptide systemic systemic im brain-cortex polypeptide mixture; organ-framed, but not a single peptide or an oral capsule product. systemic whole-body circulating", "legal_class": null }, { "id": 177, "slug": "adamax", "name": "Adamax", "aliases": [ "Adamax peptide", "Semax analog adamantane" ], "type": "Peptide", "category": "Cognitive / nootropic peptides", "goals_use_cases": [ "cognition", "focus", "energy" ], "delivery_methods": [ "nasal", "subcutaneous" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "adamax", "Adamax peptide", "Semax analog adamantane", "adamax dosage", "Adamax dose", "adamax research", "cognition", "focus", "energy" ], "feel_search": [ "cognition", "focus", "energy" ], "summary": "Adamax is an adamantane-modified Semax-family research peptide discussed as a nootropic for focus and memory.", "search_blob": "adamax adamax adamax peptide semax analog adamantane adamax adamax peptide semax analog adamantane adamax dosage adamax dose adamax research cognition focus energy cognition focus energy cognition focus energy adamax is an adamantane-modified semax-family research peptide discussed as a nootropic for focus and memory. a nasal-use account describes clarity within hours and better study recall after a week, alongside headaches and harder sleep. the author also used selank. adamax is a modified semax-family research peptide. reports include clearer thinking, little or no change, disturbed sleep and delayed fatigue. copied nasal and subq daily charts differ from individual weekly-use accounts; amounts across routes are not equivalent. cognitive / nootropic peptides peptide systemic systemic/cns-oriented nootropic peptide analog discussion. systemic whole-body circulating", "legal_class": null }, { "id": 178, "slug": "colivelin", "name": "Colivelin", "aliases": [ "CLN", "ADNF-derived peptide", "colivelin peptide" ], "type": "Peptide", "category": "Cognitive / nootropic peptides", "goals_use_cases": [ "cognition", "memory" ], "delivery_methods": [ "subcutaneous", "nasal" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "colivelin", "CLN", "ADNF-derived peptide", "colivelin peptide", "colivelin dosage", "Colivelin dose", "cognition", "memory" ], "feel_search": [ "cognition", "memory" ], "summary": "Colivelin is a synthetic hybrid of ADNF-9 and a Humanin derivative studied for neuroprotection in laboratory and animal experiments.", "search_blob": "colivelin colivelin cln adnf-derived peptide colivelin peptide colivelin cln adnf-derived peptide colivelin peptide colivelin dosage colivelin dose cognition memory cognition memory cognition memory colivelin is a synthetic hybrid of adnf-9 and a humanin derivative studied for neuroprotection in laboratory and animal experiments. the inspected vendor-associated post describes proposed neuroprotection. it provides no firsthand course, cognitive change or human onset timeline. colivelin is an engineered peptide studied in cells and animals for neuroprotection. focus and brain-fog claims express interest; the inspected material supplies no dependable completed human response. cognitive / nootropic peptides peptide systemic systemic preclinical peptide in central/peripheral injection models; capsule/pin and organ-targeting language is older lore, not established human delivery. systemic whole-body circulating", "legal_class": null }, { "id": 179, "slug": "klotho", "name": "Klotho", "aliases": [ "alpha-Klotho", "s-Klotho", "Klotho protein" ], "type": "Peptide", "category": "Longevity & cellular energy", "goals_use_cases": [ "longevity", "cognition", "cardiovascular" ], "delivery_methods": [ "subcutaneous", "IV" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "klotho", "alpha-Klotho", "s-Klotho", "Klotho protein", "klotho peptide", "klotho dosage", "longevity", "cognition", "cardiovascular" ], "feel_search": [ "longevity", "cognition", "cardiovascular" ], "summary": "Klotho is an aging-related protein, not a single short peptide; consumer products may use different constructs and are discussed for cognition and longevity.", "search_blob": "klotho klotho alpha-klotho s-klotho klotho protein klotho alpha-klotho s-klotho klotho protein klotho peptide klotho dosage longevity cognition cardiovascular longevity cognition cardiovascular longevity cognition cardiovascular klotho is an aging-related protein, not a single short peptide; consumer products may use different constructs and are discussed for cognition and longevity. one evolving account described an altered state, two poor nights of sleep and later perceived mood or cognition benefits. other treatment changes make a typical effect impossible to infer. klotho is a naturally occurring protein studied in aging biology; similarly named injectable products may contain different constructs. reports include perceived mood benefits, no effect, sensory overload and sleep changes that reverse over time. longevity & cellular energy peptide systemic systemic biology for native \u03b1-klotho; gray products may be antibodies, fragments or modified proteins, so identity and distribution cannot be assumed. systemic whole-body circulating", "legal_class": null }, { "id": 180, "slug": "17-alpha-estradiol", "name": "17\u03b1-Estradiol", "aliases": [ "17-alpha-estradiol", "17a-E2", "alfatradiol (related)" ], "type": "Non-peptide", "category": "Longevity & cellular energy", "goals_use_cases": [ "longevity", "hormone support", "insulin sensitivity", "cognition", "skin/hair" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Mixed", "misspellings_search_terms": [ "17-alpha-estradiol", "17 alpha estradiol", "17alphaestradiol", "17\u03b1-Estradiol", "17a-E2", "alfatradiol (related)", "longevity", "hormone support", "insulin sensitivity", "cognition", "skin/hair" ], "feel_search": [ "longevity", "hormone support", "insulin sensitivity", "cognition", "skin/hair" ], "summary": "17\u03b1-estradiol is a steroid isomer discussed for experimental longevity and topical hair use. Hair responses are mixed, and non-feminizing marketing does not establish freedom\u2026", "search_blob": "17\u03b1-estradiol 17-alpha-estradiol 17-alpha-estradiol 17a-e2 alfatradiol (related) 17-alpha-estradiol 17 alpha estradiol 17alphaestradiol 17\u03b1-estradiol 17a-e2 alfatradiol (related) longevity hormone support insulin sensitivity cognition skin/hair longevity hormone support insulin sensitivity cognition skin/hair longevity hormone support insulin sensitivity cognition skin/hair 17\u03b1-estradiol is a steroid isomer discussed for experimental longevity and topical hair use. hair responses are mixed, and non-feminizing marketing does not establish freedom\u2026 no dependable immediate benefit emerges from this thread. one oral log reports acne; a separate sublingual account describes irritation from its alcohol vehicle. 17\u03b1-estradiol is a steroid isomer discussed for experimental longevity and topical hair use. hair responses are mixed, and non-feminizing marketing does not establish freedom from hormone effects. 17\u03b1-estradiol is not 17\u03b2/hrt estradiol. \u201cnon-feminizing\u201d is not a guarantee of no endocrine effects; oral and topical preparations are different. longevity & cellular energy non-peptide mixed mixed \u2014 oral longevity experiments and topical hair (alfatradiol) discussion; not a joint-targeted injection. mixed local systemic", "legal_class": null }, { "id": 181, "slug": "l-carnitine", "name": "L-Carnitine (injectable)", "aliases": [ "L-carnitine 500mg/mL", "carnitine injection", "levocarnitine" ], "type": "Non-peptide", "category": "Mitochondrial & metabolic compounds", "goals_use_cases": [ "fat loss", "energy", "performance", "recovery" ], "delivery_methods": [ "intramuscular", "subcutaneous", "oral", "IV" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "l-carnitine", "l carnitine", "lcarnitine", "L-Carnitine (injectable)", "l-carnitine-(injectable)", "L-carnitine 500mg/mL", "fat loss", "energy", "performance", "recovery" ], "feel_search": [ "fat loss", "energy", "performance", "recovery" ], "summary": "L-carnitine helps transport fatty acids for energy use; oral and injectable forms are discussed for exercise and recovery, while ALCAR has a separate nootropic niche.", "search_blob": "l-carnitine (injectable) l-carnitine l-carnitine 500mg/ml carnitine injection levocarnitine l-carnitine l carnitine lcarnitine l-carnitine (injectable) l-carnitine-(injectable) l-carnitine 500mg/ml fat loss energy performance recovery fat loss energy performance recovery fat loss energy performance recovery l-carnitine helps transport fatty acids for energy use; oral and injectable forms are discussed for exercise and recovery, while alcar has a separate nootropic niche. some injectable users describe better pumps or endurance, while others report a fading early boost or no benefit. local soreness can persist; these experiences cannot be transferred directly to oral carnitine or alcar. injectable l-carnitine is discussed for training and fat loss. reports include better pumps or endurance, an early boost that fades, no benefit and persistent injection soreness; workout changes do not establish fat loss. mitochondrial & metabolic compounds non-peptide systemic systemic metabolic co-factor / supplement. systemic whole-body circulating", "legal_class": null }, { "id": 182, "slug": "triptorelin", "name": "Triptorelin", "aliases": [ "Trelstar", "Decapeptyl", "GnRH agonist trip" ], "type": "Peptide", "category": "Sexual / reproductive", "goals_use_cases": [ "hormone support", "fertility" ], "delivery_methods": [ "intramuscular", "subcutaneous" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "triptorelin", "Trelstar", "Decapeptyl", "GnRH agonist trip", "triptorelin peptide", "triptorelin dosage", "hormone support", "fertility" ], "feel_search": [ "hormone support", "fertility" ], "summary": "Triptorelin is a synthetic GnRH agonist used in medical injections; short-acting products and long-acting depots have different release profiles.", "search_blob": "triptorelin triptorelin trelstar decapeptyl gnrh agonist trip triptorelin trelstar decapeptyl gnrh agonist trip triptorelin peptide triptorelin dosage hormone support fertility hormone support fertility hormone support fertility triptorelin is a synthetic gnrh agonist used in medical injections; short-acting products and long-acting depots have different release profiles. one multi-drug user reported renewed libido while otherwise feeling much the same, and could not tell what triptorelin contributed. triptorelin is an injected gnrh agonist: initial hormone stimulation can become suppression with continued exposure. post-steroid accounts range from renewed libido to failed recovery or prolonged illness, often with other drugs. sexual / reproductive peptide systemic systemic injected gnrh agonist; parent clearance, depot release and endocrine effects have different clocks. systemic whole-body circulating", "legal_class": null }, { "id": 183, "slug": "hmg", "name": "HMG (Menotropin)", "aliases": [ "Human Menopausal Gonadotropin", "Menopur", "hMG 75IU" ], "type": "Peptide", "category": "Sexual / reproductive", "goals_use_cases": [ "fertility", "hormone support" ], "delivery_methods": [ "subcutaneous", "intramuscular" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "hmg", "HMG (Menotropin)", "hmg-(menotropin)", "Human Menopausal Gonadotropin", "Menopur", "hMG 75IU", "fertility", "hormone support" ], "feel_search": [ "fertility", "hormone support" ], "summary": "HMG (menotropins) is a urinary-derived fertility medicine supplying FSH and LH activity; male fertility discussions often combine it with hCG.", "search_blob": "hmg (menotropin) hmg human menopausal gonadotropin menopur hmg 75iu hmg hmg (menotropin) hmg-(menotropin) human menopausal gonadotropin menopur hmg 75iu fertility hormone support fertility hormone support fertility hormone support hmg (menotropins) is a urinary-derived fertility medicine supplying fsh and lh activity; male fertility discussions often combine it with hcg. injection redness, soreness or bruising may be more noticeable than any immediate benefit. fertility response is followed through tests and treatment outcomes over weeks to months. hmg (menotropins) is a fertility medicine supplying fsh and lh activity. reports describe mixed fertility outcomes and injection reactions, with other treatments complicating attribution. sexual / reproductive peptide systemic systemic fsh/lh activity for fertility care; labeled ovarian stimulation differs from off-label male hmg/hcg use. systemic whole-body circulating", "legal_class": null }, { "id": 184, "slug": "carbetocin", "name": "Carbetocin", "aliases": [ "Pabal", "Duratocin", "long-acting oxytocin analog" ], "type": "Peptide", "category": "Sleep / mood", "goals_use_cases": [ "mood", "anxiety", "libido", "postpartum uterine atony / bleeding prevention (medical)", "PWS anxiousness (investigational)", "PWS hyperphagia (investigational)" ], "delivery_methods": [ "nasal", "subcutaneous" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "carbetocin", "Pabal", "Duratocin", "long-acting oxytocin analog", "carbetocin peptide", "carbetocin dosage", "mood / emotional regulation (PWS caregiver reports)", "anxiety (PWS caregiver reports)", "food preoccupation (PWS caregiver reports)" ], "feel_search": [ "mood / emotional regulation (PWS caregiver reports)", "anxiety (PWS caregiver reports)", "food preoccupation (PWS caregiver reports)" ], "summary": "Carbetocin is a long-acting oxytocin analogue used medically after childbirth; an intranasal formulation was separately studied for Prader-Willi syndrome.", "search_blob": "carbetocin carbetocin pabal duratocin long-acting oxytocin analog carbetocin pabal duratocin long-acting oxytocin analog carbetocin peptide carbetocin dosage mood / emotional regulation (pws caregiver reports) anxiety (pws caregiver reports) food preoccupation (pws caregiver reports) mood anxiety libido postpartum uterine atony / bleeding prevention (medical) pws anxiousness (investigational) pws hyperphagia (investigational) mood / emotional regulation (pws caregiver reports) anxiety (pws caregiver reports) food preoccupation (pws caregiver reports) carbetocin is a long-acting oxytocin analogue used medically after childbirth; an intranasal formulation was separately studied for prader-willi syndrome. caregivers described less anxiety and better day-to-day behavior in some children, despite the intranasal trial missing its overall endpoints. carbetocin is a peptide medicine used to help prevent excessive bleeding after childbirth. separate nasal-spray research collected favorable caregiver impressions but did not show benefit over placebo. sleep / mood peptide systemic systemic \u2014 an oxytocin analogue used iv/im after childbirth; intranasal pws research is a separate route and indication. systemic whole-body circulating", "legal_class": null }, { "id": 185, "slug": "davunetide", "name": "Davunetide (NAP)", "aliases": [ "NAP", "NAPVSIPQ", "davunetide peptide" ], "type": "Peptide", "category": "Cognitive / nootropic peptides", "goals_use_cases": [ "cognition", "memory" ], "delivery_methods": [ "nasal" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "davunetide", "Davunetide (NAP)", "davunetide-(nap)", "NAP", "NAPVSIPQ", "davunetide peptide", "cognition", "memory" ], "feel_search": [ "cognition", "memory" ], "summary": "Davunetide (NAP) is an ADNP-derived eight-amino-acid research peptide developed for intranasal neuroprotection studies.", "search_blob": "davunetide (nap) davunetide nap napvsipq davunetide peptide davunetide davunetide (nap) davunetide-(nap) nap napvsipq davunetide peptide cognition memory cognition memory cognition memory davunetide (nap) is an adnp-derived eight-amino-acid research peptide developed for intranasal neuroprotection studies. the inspected post asks about davunetide, but the experience replies concern other nootropics. a detailed commenter explicitly says they have not tried it. davunetide, or nap, is an experimental eight-amino-acid peptide developed as a nasal treatment. memory and brain-fog interest exceeds the checked firsthand experience; its major mci and psp trial outcomes were negative. cognitive / nootropic peptides peptide systemic systemic cns-directed investigational nap octapeptide delivered by metered intranasal spray in human trials; not a khavinson bioregulator. systemic whole-body circulating", "legal_class": null }, { "id": 186, "slug": "fgl", "name": "FGL Peptide", "aliases": [ "FG Loop", "NCAM mimetic", "FGL peptide" ], "type": "Peptide", "category": "Cognitive / nootropic peptides", "goals_use_cases": [ "cognition", "memory" ], "delivery_methods": [ "subcutaneous", "nasal" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "fgl", "FGL Peptide", "fgl-peptide", "FG Loop", "NCAM mimetic", "fgl dosage", "cognition", "memory" ], "feel_search": [ "cognition", "memory" ], "summary": "FGL-family peptides mimic a fragment of neural cell adhesion molecule and are studied for memory-related signaling; FGLL is a specific research form.", "search_blob": "fgl peptide fgl fg loop ncam mimetic fgl peptide fgl fgl peptide fgl-peptide fg loop ncam mimetic fgl dosage cognition memory cognition memory cognition memory fgl-family peptides mimic a fragment of neural cell adhesion molecule and are studied for memory-related signaling; fgll is a specific research form. the article records an injected-fgl learning/mood account and a nasal recall claim, alongside mixed secondhand ha-fgl reports. the reddit fgl/dihexa question supplies no completed combination outcome. fgl-family peptides mimic part of a nerve-cell protein. sparse learning and mood claims coexist with adverse ha-fgl reports; forms and routes are not interchangeable. cognitive / nootropic peptides peptide systemic synthetic ncam-derived fg-loop mimetic studied intranasally in one small phase i trial; proposed cognitive effects remain mainly preclinical. systemic whole-body circulating", "legal_class": null }, { "id": 187, "slug": "orexin-a", "name": "Orexin A", "aliases": [ "Hypocretin-1", "OX-A", "orexin peptide" ], "type": "Peptide", "category": "Sleep / mood", "goals_use_cases": [ "energy", "focus", "sleep" ], "delivery_methods": [ "nasal" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "orexin-a", "orexin a", "orexina", "Hypocretin-1", "OX-A", "orexin peptide", "energy", "focus", "sleep" ], "feel_search": [ "energy", "focus", "sleep" ], "summary": "Orexin-A is a brain peptide involved in wakefulness and appetite; experimental nasal products are discussed for staying awake.", "search_blob": "orexin a orexin-a hypocretin-1 ox-a orexin peptide orexin-a orexin a orexina hypocretin-1 ox-a orexin peptide energy focus sleep energy focus sleep energy focus sleep orexin-a is a brain peptide involved in wakefulness and appetite; experimental nasal products are discussed for staying awake. orexin a is a brain signaling peptide discussed for wakefulness. one nasal user recalled about four hours awake; others felt little or nothing, and a separate account reported prolonged insomnia despite little acute sensation. sleep / mood peptide systemic wake/appetite neuropeptide; intranasal community use and systemic research do not establish selective brain delivery. systemic whole-body circulating", "legal_class": null }, { "id": 188, "slug": "thymopentin", "name": "Thymopentin", "aliases": [ "TP-5", "RKDVY", "thymopoietin pentapeptide" ], "type": "Peptide", "category": "Immune / antimicrobial", "goals_use_cases": [ "immune", "recovery" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "thymopentin", "TP-5", "RKDVY", "thymopoietin pentapeptide", "thymopentin peptide", "thymopentin dosage", "immune", "recovery" ], "feel_search": [ "immune", "recovery" ], "summary": "Thymopentin (TP-5) is a synthetic five-amino-acid fragment of thymopoietin studied for immune function.", "search_blob": "thymopentin thymopentin tp-5 rkdvy thymopoietin pentapeptide thymopentin tp-5 rkdvy thymopoietin pentapeptide thymopentin peptide thymopentin dosage immune recovery immune recovery immune recovery thymopentin (tp-5) is a synthetic five-amino-acid fragment of thymopoietin studied for immune function. the inspected purchaser thread has no personal result after use; its uti-prevention story is second-hand. thymopentin (tp-5) is a defined five-amino-acid peptide studied for immune function. the inspected community discussions offer questions and secondhand claims, without a dependable firsthand benefit timeline. immune / antimicrobial peptide systemic systemic immune-modulation research around a defined thymopoietin pentapeptide; plasma degradation is rapid ex vivo. systemic whole-body circulating", "legal_class": null }, { "id": 189, "slug": "ac-sdkp", "name": "Ac-SDKP", "aliases": [ "N-acetyl-Ser-Asp-Lys-Pro", "AcSDKP", "thymosin beta-4 metabolite" ], "type": "Peptide", "category": "Healing & repair", "goals_use_cases": [ "anti fibrotic", "cardiovascular", "recovery" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "ac-sdkp", "ac sdkp", "acsdkp", "N-acetyl-Ser-Asp-Lys-Pro", "thymosin beta-4 metabolite", "ac-sdkp peptide", "anti fibrotic", "cardiovascular", "recovery" ], "feel_search": [ "anti fibrotic", "cardiovascular", "recovery" ], "summary": "Ac-SDKP is a four-amino-acid fragment of thymosin-\u03b24 studied for reducing tissue scarring; it differs from the fragment sold as TB-500.", "search_blob": "ac-sdkp ac-sdkp n-acetyl-ser-asp-lys-pro acsdkp thymosin beta-4 metabolite ac-sdkp ac sdkp acsdkp n-acetyl-ser-asp-lys-pro thymosin beta-4 metabolite ac-sdkp peptide anti fibrotic cardiovascular recovery anti fibrotic cardiovascular recovery anti fibrotic cardiovascular recovery ac-sdkp is a four-amino-acid fragment of thymosin-\u03b24 studied for reducing tissue scarring; it differs from the fragment sold as tb-500. the inspected thread discusses which thymosin fragment is in a product. it does not establish a firsthand benefit or a reliable feel timeline. ac-sdkp is a naturally occurring four-amino-acid fragment discussed for tissue scarring. product lists and fragment debates do not establish a dependable standalone recovery benefit. healing & repair peptide systemic endogenous peptide studied for systemic anti-fibrotic effects; organ-focused discussion does not establish local targeting or oral delivery. systemic whole-body circulating", "legal_class": null }, { "id": 190, "slug": "apitegromab", "name": "Apitegromab", "aliases": [ "SRK-015", "apitegromab antibody" ], "type": "Non-peptide", "category": "Growth factors / muscle", "goals_use_cases": [ "muscle growth", "performance" ], "delivery_methods": [ "IV" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "apitegromab", "SRK-015", "apitegromab antibody", "apitegromab peptide", "apitegromab dosage", "Apitegromab dose", "muscle growth", "performance" ], "feel_search": [ "muscle growth", "performance" ], "summary": "Apitegromab is an antibody that blocks myostatin activation. Its U.S. prescription product is approved for a defined spinal muscular atrophy population; other research does not\u2026", "search_blob": "apitegromab apitegromab srk-015 apitegromab antibody apitegromab srk-015 apitegromab antibody apitegromab peptide apitegromab dosage apitegromab dose muscle growth performance muscle growth performance muscle growth performance apitegromab is an antibody that blocks myostatin activation. its u.s. prescription product is approved for a defined spinal muscular atrophy population; other research does not\u2026 patients discuss hoped-for small functional gains and the limits of longstanding disease. the inspected conversation is expectation, not a treatment diary. apitegromab is a prescription antibody for a defined spinal muscular atrophy population. public patient discussions here express hopes for useful movement gains, without a dependable firsthand infusion-to-effect timeline. growth factors / muscle non-peptide systemic systemic anti-myostatin antibody. systemic whole-body circulating", "legal_class": null }, { "id": 191, "slug": "gdf-11", "name": "GDF-11", "aliases": [ "GDF11", "growth differentiation factor 11" ], "type": "Peptide", "category": "Growth factors / muscle", "goals_use_cases": [ "longevity", "muscle growth", "cognition" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "gdf-11", "gdf 11", "gdf11", "growth differentiation factor 11", "gdf-11 peptide", "gdf-11 dosage", "longevity", "muscle growth", "cognition" ], "feel_search": [ "longevity", "muscle growth", "cognition" ], "summary": "GDF11 is a growth-factor protein discussed in longevity circles as a possible aging signal; it is different from short organ-targeted bioregulator peptides.", "search_blob": "gdf-11 gdf-11 gdf11 growth differentiation factor 11 gdf-11 gdf 11 gdf11 growth differentiation factor 11 gdf-11 peptide gdf-11 dosage longevity muscle growth cognition longevity muscle growth cognition longevity muscle growth cognition gdf11 is a growth-factor protein discussed in longevity circles as a possible aging signal; it is different from short organ-targeted bioregulator peptides. accounts range from no noticeable change to claimed endurance gains. one long-term tracker reported none of the promoted reaction-time or heart-rate-variability improvements. these uncontrolled reports do not establish an anti-aging benefit. gdf-11 is a signaling protein discussed for longevity, stamina and cognition. accounts include little change, claimed endurance gains, agitation and reflux; no typical human response or safe anti-aging dose is established. growth factors / muscle peptide systemic systemic \u2014 a circulating tgf-\u03b2-family growth factor; research and self-reports concern whole-body exposure, not an organ-specific capsule. systemic whole-body circulating", "legal_class": null }, { "id": 192, "slug": "bromantane", "name": "Bromantane", "aliases": [ "Ladasten", "NP-160", "bromantan" ], "type": "Non-peptide", "category": "Cognitive research compounds", "goals_use_cases": [ "energy", "performance", "focus", "mood" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "bromantane", "Ladasten", "NP-160", "bromantan", "bromantane peptide", "bromantane dosage", "energy", "performance", "focus", "mood" ], "feel_search": [ "energy", "performance", "focus", "mood" ], "summary": "Bromantane is an oral small-molecule pill, not a peptide, sold as Ladasten in Russia and discussed for fatigue, motivation and easier task initiation.", "search_blob": "bromantane bromantane ladasten np-160 bromantan bromantane ladasten np-160 bromantan bromantane peptide bromantane dosage energy performance focus mood energy performance focus mood energy performance focus mood bromantane is an oral small-molecule pill, not a peptide, sold as ladasten in russia and discussed for fatigue, motivation and easier task initiation. favorable accounts describe easier task initiation and less mental friction. others report no benefit, anxious stimulation or insomnia; oral and nasal experiences differ. bromantane (ladasten) is a small-molecule drug discussed for fatigue. reports range from easier task initiation to no benefit, sleepiness or insomnia; oral, sublingual and nasal accounts differ. cognitive research compounds non-peptide systemic taken by mouth for whole-body fatigue and motivation talk \u2014 not a peptide and not a typical stimulant. systemic whole-body circulating", "legal_class": null }, { "id": 193, "slug": "acetyl-tetrapeptide-3", "name": "Acetyl Tetrapeptide-3", "aliases": [ "Capixyl peptide", "acetyl tetrapeptide-3 hair" ], "type": "Peptide", "category": "Skin, hair & tissue remodeling", "goals_use_cases": [ "skin/hair", "recovery" ], "delivery_methods": [ "topical" ], "discussion_popularity": "Emerging", "reach": "Local", "misspellings_search_terms": [ "acetyl-tetrapeptide-3", "acetyl tetrapeptide 3", "acetyltetrapeptide3", "Acetyl Tetrapeptide-3", "Capixyl peptide", "acetyl tetrapeptide-3 hair", "skin/hair", "recovery" ], "feel_search": [ "skin/hair", "recovery" ], "summary": "Acetyl Tetrapeptide-3 is a cosmetic peptide used in scalp and lash products; Capixyl combines it with red-clover extract.", "search_blob": "acetyl tetrapeptide-3 acetyl-tetrapeptide-3 capixyl peptide acetyl tetrapeptide-3 hair acetyl-tetrapeptide-3 acetyl tetrapeptide 3 acetyltetrapeptide3 acetyl tetrapeptide-3 capixyl peptide acetyl tetrapeptide-3 hair skin/hair recovery skin/hair recovery skin/hair recovery acetyl tetrapeptide-3 is a cosmetic peptide used in scalp and lash products; capixyl combines it with red-clover extract. one multi-ingredient serum review reports brief early scalp tingling and less shedding by week three. it cannot attribute that change to this peptide alone. acetyl tetrapeptide-3 is a cosmetic peptide found in multi-ingredient hair serums. users report less shedding or fuller-looking hair, but also little growth, no benefit and scalp discomfort. skin, hair & tissue remodeling peptide local local \u2014 a scalp/skin serum, not a whole-body shot. local site pin topical", "legal_class": null }, { "id": 194, "slug": "pramlintide", "name": "Pramlintide", "aliases": [ "Symlin", "pramlintide acetate", "amylin analog pramlintide" ], "type": "Peptide", "category": "Metabolic / GLP-1 class", "goals_use_cases": [ "fat loss", "appetite suppression", "insulin sensitivity" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "pramlintide", "Symlin", "pramlintide acetate", "amylin analog pramlintide", "pramlintide peptide", "pramlintide dosage", "fat loss", "appetite suppression", "insulin sensitivity" ], "feel_search": [ "fat loss", "appetite suppression", "insulin sensitivity" ], "summary": "Pramlintide (Symlin) is an injectable amylin analogue used with insulin for mealtime glucose control and discussed for satiety.", "search_blob": "pramlintide pramlintide symlin pramlintide acetate amylin analog pramlintide pramlintide symlin pramlintide acetate amylin analog pramlintide pramlintide peptide pramlintide dosage fat loss appetite suppression insulin sensitivity fat loss appetite suppression insulin sensitivity fat loss appetite suppression insulin sensitivity pramlintide (symlin) is an injectable amylin analogue used with insulin for mealtime glucose control and discussed for satiety. one long-term user described light early nausea that later faded, but found injections before every meal burdensome. pramlintide (symlin) is an injectable amylin analogue used alongside mealtime insulin. users describe smaller meals and easier glucose control, but nausea, lows and extra meal-time work can outweigh those benefits. metabolic / glp-1 class peptide systemic systemic amylin-pathway peptide for meal-time metabolic control. systemic whole-body circulating", "legal_class": null }, { "id": 195, "slug": "teduglutide", "name": "Teduglutide", "aliases": [ "Gattex", "Revestive", "GLP-2 analog" ], "type": "Peptide", "category": "Gut & inflammation peptides", "goals_use_cases": [ "gut health", "recovery" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "teduglutide", "Gattex", "Revestive", "GLP-2 analog", "teduglutide peptide", "teduglutide dosage", "gut health", "recovery" ], "feel_search": [ "gut health", "recovery" ], "summary": "Teduglutide (Gattex/Revestive) is a GLP-2 analogue used for short-bowel syndrome to improve intestinal absorption.", "search_blob": "teduglutide teduglutide gattex revestive glp-2 analog teduglutide gattex revestive glp-2 analog teduglutide peptide teduglutide dosage gut health recovery gut health recovery gut health recovery teduglutide (gattex/revestive) is a glp-2 analogue used for short-bowel syndrome to improve intestinal absorption. one person after major bowel resection reported better symptom control alongside bloating and gas; longstanding no-burp symptoms complicate attribution. teduglutide is a glp-2 analogue used in short-bowel care. patient reports include less iv support and better symptom control alongside bloating, pain and other adverse experiences. gut & inflammation peptides peptide systemic systemic glp-2 analog for sbs. systemic whole-body circulating", "legal_class": null }, { "id": 196, "slug": "anamorelin", "name": "Anamorelin", "aliases": [ "ONO-7643", "Adlumiz", "anamorelin HCl" ], "type": "Peptide", "category": "Growth hormone axis", "goals_use_cases": [ "muscle growth", "appetite suppression", "performance", "appetite stimulation" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "anamorelin", "ONO-7643", "Adlumiz", "anamorelin HCl", "anamorelin peptide", "anamorelin dosage", "muscle growth", "appetite stimulation", "performance" ], "feel_search": [ "muscle growth", "appetite stimulation", "performance" ], "summary": "Anamorelin is an oral ghrelin-receptor drug developed to increase appetite and lean mass in cancer-related wasting.", "search_blob": "anamorelin anamorelin ono-7643 adlumiz anamorelin hcl anamorelin ono-7643 adlumiz anamorelin hcl anamorelin peptide anamorelin dosage muscle growth appetite stimulation performance muscle growth appetite suppression performance appetite stimulation muscle growth appetite stimulation performance anamorelin is an oral ghrelin-receptor drug developed to increase appetite and lean mass in cancer-related wasting. one early self-log reports no immediate effect, then nausea, fatigue and breathlessness around a gym session. other mixed-product accounts describe stronger hunger or better sleep, while some notice little; none isolates anamorelin's contribution. anamorelin is an oral ghrelin-receptor drug developed for cancer-related wasting. mixed-product users report stronger hunger or better sleep, while others report little change or nausea, fatigue and breathlessness. growth hormone axis peptide systemic systemic oral ghrelin mimetic. systemic whole-body circulating", "legal_class": null }, { "id": 197, "slug": "svetinorm", "name": "Svetinorm", "aliases": [ "Svetinorm peptide", "liver peptide complex" ], "type": "Peptide", "category": "Organ bioregulators", "goals_use_cases": [ "longevity", "recovery" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "svetinorm", "Svetinorm peptide", "liver peptide complex", "svetinorm dosage", "Svetinorm dose", "svetinorm research", "longevity", "recovery" ], "feel_search": [ "longevity", "recovery" ], "summary": "Svetinorm is a liver-targeted product in the Russian peptide-bioregulator tradition, marketed for liver support.", "search_blob": "svetinorm svetinorm svetinorm peptide liver peptide complex svetinorm svetinorm peptide liver peptide complex svetinorm dosage svetinorm dose svetinorm research longevity recovery longevity recovery longevity recovery svetinorm is a liver-targeted product in the russian peptide-bioregulator tradition, marketed for liver support. one multi-product user called svetinorm helpful, but the thread does not isolate its effects; another person only reported ordering it. svetinorm is an animal-liver peptide extract marketed for liver support. reports describe less abdominal discomfort or other supplements feeling noticeable again, but do not establish repaired liver function. organ bioregulators peptide systemic oral liver-tissue peptide supplement sold in bioregulator culture; organ targeting and human benefit remain unproven. systemic whole-body circulating", "legal_class": null }, { "id": 198, "slug": "sigumir", "name": "Sigumir", "aliases": [ "Sigumir peptide", "cartilage-bone bioregulator" ], "type": "Peptide", "category": "Organ bioregulators", "goals_use_cases": [ "joints & tendons", "bone health", "recovery" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "sigumir", "Sigumir peptide", "cartilage-bone bioregulator", "sigumir dosage", "Sigumir dose", "sigumir research", "joints & tendons", "bone health", "recovery" ], "feel_search": [ "joints & tendons", "bone health", "recovery" ], "summary": "Sigumir is a cartilage-derived mixture of small peptides from calves or pigs, marketed for joints; it differs from the single peptide Cartalax.", "search_blob": "sigumir sigumir sigumir peptide cartilage-bone bioregulator sigumir sigumir peptide cartilage-bone bioregulator sigumir dosage sigumir dose sigumir research joints & tendons bone health recovery joints & tendons bone health recovery joints & tendons bone health recovery sigumir is a cartilage-derived mixture of small peptides from calves or pigs, marketed for joints; it differs from the single peptide cartalax. one commenter said their knees felt more solid after a box; the original poster reported no improvement after a month and then pursued prp. these are separate histories, not one changing response. sigumir is an oral cartilage-tissue peptide mixture. reports include less pain or steadier knees and a separate month without improvement; none establishes cartilage regrowth. organ bioregulators peptide systemic cartilage/joint-framed oral extract; organ-targeting language does not establish selective human delivery. systemic whole-body circulating", "legal_class": null }, { "id": 199, "slug": "vladonix", "name": "Vladonix", "aliases": [ "Vladonix peptide", "thymus bioregulator complex" ], "type": "Peptide", "category": "Organ bioregulators", "goals_use_cases": [ "immune", "longevity" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "vladonix", "Vladonix peptide", "thymus bioregulator complex", "vladonix dosage", "Vladonix dose", "vladonix research", "immune", "longevity" ], "feel_search": [ "immune", "longevity" ], "summary": "Vladonix is a calf-thymus peptide mixture in the Russian bioregulator tradition, marketed for immune support. The organ-targeting claim does not establish selective delivery or\u2026", "search_blob": "vladonix vladonix vladonix peptide thymus bioregulator complex vladonix vladonix peptide thymus bioregulator complex vladonix dosage vladonix dose vladonix research immune longevity immune longevity immune longevity vladonix is a calf-thymus peptide mixture in the russian bioregulator tradition, marketed for immune support. the organ-targeting claim does not establish selective delivery or\u2026 one person reported better sleep, concentration, mood and digestion while trying many bioregulators together, without identifying vladonix's contribution. vladonix is an oral thymus-extract peptide mixture marketed for immune support. favorable mixed-product accounts describe better sleep, mood, digestion or comfort without isolating its contribution. organ bioregulators peptide systemic systemic oral thymus-extract product with organ-targeted marketing; not a local thymus treatment. systemic whole-body circulating", "legal_class": null }, { "id": 200, "slug": "bonomarlot", "name": "Bonomarlot", "aliases": [ "Bonomarlot peptide", "bone-marrow bioregulator" ], "type": "Peptide", "category": "Organ bioregulators", "goals_use_cases": [ "bone health", "immune", "longevity" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "bonomarlot", "Bonomarlot peptide", "bone-marrow bioregulator", "bonomarlot dosage", "Bonomarlot dose", "bonomarlot research", "bone health", "immune", "longevity" ], "feel_search": [ "bone health", "immune", "longevity" ], "summary": "Bonomarlot is a bone-marrow bioregulator product discussed for blood-cell and iron-related concerns; capsule reports are sparse.", "search_blob": "bonomarlot bonomarlot bonomarlot peptide bone-marrow bioregulator bonomarlot bonomarlot peptide bone-marrow bioregulator bonomarlot dosage bonomarlot dose bonomarlot research bone health immune longevity bone health immune longevity bone health immune longevity bonomarlot is a bone-marrow bioregulator product discussed for blood-cell and iron-related concerns; capsule reports are sparse. one long-term capsule user reports improved ferritin and hemoglobin after earlier iron treatments disappointed them. this is a lab self-report, not a known immediate feeling. bonomarlot is an animal-marrow peptide mixture marketed for blood support. one capsule user reported higher low iron-related markers; another reported less dizziness after several products were added together. organ bioregulators peptide systemic bone-marrow and blood-support discussion around an oral capsule; organ-focused claims are not a local marrow treatment. systemic whole-body circulating", "legal_class": null }, { "id": 201, "slug": "stamakort", "name": "Stamakort", "aliases": [ "Stamakort peptide", "stomach-mucosa bioregulator" ], "type": "Peptide", "category": "Organ bioregulators", "goals_use_cases": [ "gut health", "recovery" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "stamakort", "Stamakort peptide", "stomach-mucosa bioregulator", "stamakort dosage", "Stamakort dose", "stamakort research", "gut health", "recovery" ], "feel_search": [ "gut health", "recovery" ], "summary": "Stamakort is an oral peptide-mixture product marketed for stomach-lining support in the Russian bioregulator tradition; selective organ delivery is unestablished.", "search_blob": "stamakort stamakort stamakort peptide stomach-mucosa bioregulator stamakort stamakort peptide stomach-mucosa bioregulator stamakort dosage stamakort dose stamakort research gut health recovery gut health recovery gut health recovery stamakort is an oral peptide-mixture product marketed for stomach-lining support in the russian bioregulator tradition; selective organ delivery is unestablished. accounts include less pain with meals, an unclear effect in a symptom-free combined-use account and a separate stomach-upset discontinuation. the favorable author also changed diet and used other products. stamakort is an oral peptide-mixture product marketed for stomach-lining support. accounts include less pain, no identifiable effect and stomach upset; none establishes gut repair. organ bioregulators peptide systemic targeted in marketing to the stomach, but documented use is oral capsules; systemic absorption and organ-selective delivery are unestablished. systemic whole-body circulating", "legal_class": null }, { "id": 202, "slug": "ventfort", "name": "Ventfort", "aliases": [ "Ventfort peptide", "vessel bioregulator complex" ], "type": "Peptide", "category": "Organ bioregulators", "goals_use_cases": [ "cardiovascular", "longevity" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "ventfort", "Ventfort peptide", "vessel bioregulator complex", "ventfort dosage", "Ventfort dose", "ventfort research", "cardiovascular", "longevity" ], "feel_search": [ "cardiovascular", "longevity" ], "summary": "Ventfort (A-3) is a blood-vessel-tissue-derived mixture of peptide fractions marketed for vascular support.", "search_blob": "ventfort ventfort ventfort peptide vessel bioregulator complex ventfort ventfort peptide vessel bioregulator complex ventfort dosage ventfort dose ventfort research cardiovascular longevity cardiovascular longevity cardiovascular longevity ventfort (a-3) is a blood-vessel-tissue-derived mixture of peptide fractions marketed for vascular support. one person reported better sleep and wearable recovery scores while taking ventfort with chelohart and svetinorm, and acknowledged possible placebo. ventfort is a vessel-derived peptide mixture marketed for vascular support. mixed-product users report subtle changes or better wearable scores, while another reports no measurable benefit; vessel-repair claims remain unverified. organ bioregulators peptide systemic oral vessel-derived peptide mixture with vascular-target marketing; reviewed sources do not establish selective vessel delivery or an injectable route. systemic whole-body circulating", "legal_class": null }, { "id": 203, "slug": "gotratix", "name": "Gotratix", "aliases": [ "Gotratix peptide", "muscle bioregulator" ], "type": "Peptide", "category": "Organ bioregulators", "goals_use_cases": [ "muscle growth", "recovery" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "gotratix", "Gotratix peptide", "muscle bioregulator", "gotratix dosage", "Gotratix dose", "gotratix research", "muscle growth", "recovery" ], "feel_search": [ "muscle growth", "recovery" ], "summary": "Gotratix (A-18) is an animal muscle-derived peptide mixture sold in capsules, discussed for training recovery and muscle maintenance.", "search_blob": "gotratix gotratix gotratix peptide muscle bioregulator gotratix gotratix peptide muscle bioregulator gotratix dosage gotratix dose gotratix research muscle growth recovery muscle growth recovery muscle growth recovery gotratix (a-18) is an animal muscle-derived peptide mixture sold in capsules, discussed for training recovery and muscle maintenance. gotratix (a-18) is an animal-muscle peptide mixture sold in oral capsules. reports range from less soreness and better pumps during a stack to no training or recovery benefit during two months of solo use. organ bioregulators peptide systemic an oral animal-muscle peptide mixture marketed for skeletal muscle; no injectable gotratix or human distribution study was verified. systemic whole-body circulating", "legal_class": null }, { "id": 204, "slug": "libidon", "name": "Libidon", "aliases": [ "Libidon peptide", "prostate bioregulator complex" ], "type": "Peptide", "category": "Organ bioregulators", "goals_use_cases": [ "sexual health", "hormone support", "recovery" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "libidon", "Libidon peptide", "prostate bioregulator complex", "libidon dosage", "Libidon dose", "libidon research", "sexual health", "hormone support", "recovery" ], "feel_search": [ "sexual health", "hormone support", "recovery" ], "summary": "Libidon A-16 is an animal prostate-derived peptide mixture sold in capsules, discussed for urinary symptoms and prostate support.", "search_blob": "libidon libidon libidon peptide prostate bioregulator complex libidon libidon peptide prostate bioregulator complex libidon dosage libidon dose libidon research sexual health hormone support recovery sexual health hormone support recovery sexual health hormone support recovery libidon a-16 is an animal prostate-derived peptide mixture sold in capsules, discussed for urinary symptoms and prostate support. one oral user questioned early gi symptoms, then later reported urinary and erection improvement with tadalafil and other changes. separate reports describe gradual benefit or no improvement; these are not a typical sequence. libidon a-16 is an oral prostate-derived peptide mixture. reports include gradual urinary improvement, uncertain effects and no benefit; other treatment changes limit attribution. organ bioregulators peptide systemic systemic oral product with prostate-targeted marketing; human tissue distribution has not been established. systemic whole-body circulating", "legal_class": null }, { "id": 205, "slug": "ac-262", "name": "AC-262", "aliases": [ "AC262", "AC-262536" ], "type": "Non-peptide", "category": "Performance / endurance", "goals_use_cases": [ "muscle growth", "performance" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "ac-262", "ac 262", "ac262", "AC-262536", "ac-262 peptide", "ac-262 dosage", "muscle growth", "performance" ], "feel_search": [ "muscle growth", "performance" ], "summary": "AC-262 is an oral SARM. Reports range from an early mental lift to no worthwhile strength change; one 4-week Cardarine-stacked run described bloating and lackluster results.", "search_blob": "ac-262 ac-262 ac262 ac-262536 ac-262 ac 262 ac262 ac-262536 ac-262 peptide ac-262 dosage muscle growth performance muscle growth performance muscle growth performance ac-262 is an oral sarm. reports range from an early mental lift to no worthwhile strength change; one 4-week cardarine-stacked run described bloating and lackluster results. one testosterone user reports early energy and mood lift, then more fullness but little strength change. other accounts describe anxiety, sleep disruption, bloating or little extra progress. these uncontrolled reports do not isolate ac-262 or establish a typical response. ac-262 is an oral sarm. reports range from an early mental lift to no worthwhile strength change; one 4-week cardarine-stacked run described bloating and lackluster results. performance / endurance non-peptide systemic systemic sarm research chem. systemic whole-body circulating", "legal_class": null }, { "id": 206, "slug": "lgd-3303", "name": "LGD-3303", "aliases": [ "LGD3303", "LGD 3303" ], "type": "Non-peptide", "category": "Performance / endurance", "goals_use_cases": [ "muscle growth", "performance", "bone health" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "lgd-3303", "lgd 3303", "lgd3303", "lgd-3303 peptide", "lgd-3303 dosage", "LGD-3303 dose", "muscle growth", "performance", "bone health" ], "feel_search": [ "muscle growth", "performance", "bone health" ], "summary": "LGD-3303 is an experimental nonsteroidal androgen-receptor modulator, discussed for muscle and strength; it is a different molecule from LGD-4033.", "search_blob": "lgd-3303 lgd-3303 lgd3303 lgd 3303 lgd-3303 lgd 3303 lgd3303 lgd-3303 peptide lgd-3303 dosage lgd-3303 dose muscle growth performance bone health muscle growth performance bone health muscle growth performance bone health lgd-3303 is an experimental nonsteroidal androgen-receptor modulator, discussed for muscle and strength; it is a different molecule from lgd-4033. a week-four account described more definition, weight gain and better lifts, but the visible exchange did not settle whether the tablets were lgd-3303 or lgd-4033. it cannot establish a typical 3303 response. lgd-3303 is an experimental nonsteroidal sarm, distinct from lgd-4033. reports describe stronger lifts and a harder-looking physique alongside nonresponse, hair shedding, fatigue and hormonal suppression. do not mix up with lgd-4033 charts. performance / endurance non-peptide systemic systemic oral sarm research chemical; human pharmacokinetics and clinical efficacy are not established. systemic whole-body circulating", "legal_class": null }, { "id": 207, "slug": "meldonium", "name": "Meldonium", "aliases": [ "Mildronate", "MET-88", "meldonium dihydrate" ], "type": "Non-peptide", "category": "Performance / endurance", "goals_use_cases": [ "performance", "cardiovascular", "recovery" ], "delivery_methods": [ "oral", "IV" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "meldonium", "Mildronate", "MET-88", "meldonium dihydrate", "meldonium peptide", "meldonium dosage", "performance", "cardiovascular", "recovery" ], "feel_search": [ "performance", "cardiovascular", "recovery" ], "summary": "Meldonium (Mildronate) is a metabolic drug that affects fuel use, discussed for fatigue and endurance as well as regional cardiac uses.", "search_blob": "meldonium meldonium mildronate met-88 meldonium dihydrate meldonium mildronate met-88 meldonium dihydrate meldonium peptide meldonium dosage performance cardiovascular recovery performance cardiovascular recovery performance cardiovascular recovery meldonium (mildronate) is a metabolic drug that affects fuel use, discussed for fatigue and endurance as well as regional cardiac uses. some report easier physical activity, others only slight recovery or no energy gain. fatigue, disrupted sleep or a crash also appear; the small number of accounts does not establish a typical response. meldonium is a metabolic medicine discussed for fatigue and endurance. accounts include easier activity, little benefit, reduced power, disrupted sleep and crashes. performance / endurance non-peptide systemic systemic metabolic modulator reported orally; intravenous administration appears in medical and pharmacokinetic contexts. systemic whole-body circulating", "legal_class": null }, { "id": 208, "slug": "sotatercept", "name": "Sotatercept", "aliases": [ "Winrevair", "ACE-011 (related)", "sotatercept-csrk" ], "type": "Non-peptide", "category": "Growth factors / muscle", "goals_use_cases": [ "muscle growth", "cardiovascular" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "sotatercept", "Winrevair", "ACE-011 (related)", "sotatercept-csrk", "sotatercept peptide", "sotatercept dosage", "muscle growth", "cardiovascular" ], "feel_search": [ "muscle growth", "cardiovascular" ], "summary": "Sotatercept (Winrevair) is an activin-signaling inhibitor used for pulmonary arterial hypertension, a serious blood-vessel disease of the lungs.", "search_blob": "sotatercept sotatercept winrevair ace-011 (related) sotatercept-csrk sotatercept winrevair ace-011 (related) sotatercept-csrk sotatercept peptide sotatercept dosage muscle growth cardiovascular muscle growth cardiovascular muscle growth cardiovascular sotatercept (winrevair) is an activin-signaling inhibitor used for pulmonary arterial hypertension, a serious blood-vessel disease of the lungs. patients report easier breathing or no clear subjective improvement; some describe fatigue, headaches or diarrhea after treatment. sotatercept is a prescription fusion protein used for pulmonary arterial hypertension. patients report easier breathing, persistent fatigue, no felt improvement or adverse effects; individual experience varies. growth factors / muscle non-peptide systemic systemic actriia fusion biologic for pah. systemic whole-body circulating", "legal_class": null }, { "id": 209, "slug": "lac-phe", "name": "Lac-Phe", "aliases": [ "Lactoyl-Phenylalanine", "N-lactoyl-phenylalanine" ], "type": "Non-peptide", "category": "Performance / endurance", "goals_use_cases": [ "performance", "appetite suppression", "fat loss" ], "delivery_methods": [ "oral", "subcutaneous" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "lac-phe", "lac phe", "lacphe", "Lactoyl-Phenylalanine", "N-lactoyl-phenylalanine", "lac-phe peptide", "performance", "appetite suppression", "fat loss" ], "feel_search": [ "performance", "appetite suppression", "fat loss" ], "summary": "Lac-Phe is a metabolite formed from lactate and phenylalanine, studied as an exercise-linked signal that may influence appetite.", "search_blob": "lac-phe lac-phe lactoyl-phenylalanine n-lactoyl-phenylalanine lac-phe lac phe lacphe lactoyl-phenylalanine n-lactoyl-phenylalanine lac-phe peptide performance appetite suppression fat loss performance appetite suppression fat loss performance appetite suppression fat loss lac-phe is a metabolite formed from lactate and phenylalanine, studied as an exercise-linked signal that may influence appetite. lac-phe is a small metabolite made from lactate and phenylalanine that rises after exercise. the inspected discussions show appetite-control interest but no confirmed administration log establishing how taking it feels. performance / endurance non-peptide systemic endogenous circulating exercise metabolite; exogenous human use remains experimental, and no oral or subq consumer route was verified. systemic whole-body circulating", "legal_class": null }, { "id": 210, "slug": "pielotax", "name": "Pielotax", "aliases": [ "Pielotax peptide", "kidney bioregulator" ], "type": "Peptide", "category": "Organ bioregulators", "goals_use_cases": [ "recovery", "longevity" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "pielotax", "Pielotax peptide", "kidney bioregulator", "pielotax dosage", "Pielotax dose", "pielotax research", "recovery", "longevity" ], "feel_search": [ "recovery", "longevity" ], "summary": "Pielotax is a kidney-targeted product in the Russian peptide-bioregulator tradition; organ-support claims have limited independent human evidence.", "search_blob": "pielotax pielotax pielotax peptide kidney bioregulator pielotax pielotax peptide kidney bioregulator pielotax dosage pielotax dose pielotax research recovery longevity recovery longevity recovery longevity pielotax is a kidney-targeted product in the russian peptide-bioregulator tradition; organ-support claims have limited independent human evidence. a commercial diary described less dizziness with a kidney-product stack; changing product names and several other agents prevent isolating pielotax. pielotax is an oral kidney-bioregulator mixture. favorable accounts involve other products or different kidney tests, so they do not establish restored filtration. organ bioregulators peptide systemic marketed for kidney support; oral use does not establish selective kidney delivery or tissue repair. systemic whole-body circulating", "legal_class": null }, { "id": 211, "slug": "visoluten", "name": "Visoluten", "aliases": [ "Visoluten peptide", "retina bioregulator" ], "type": "Peptide", "category": "Organ bioregulators", "goals_use_cases": [ "cognition", "longevity" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "visoluten", "Visoluten peptide", "retina bioregulator", "visoluten dosage", "Visoluten dose", "visoluten research", "cognition", "longevity" ], "feel_search": [ "cognition", "longevity" ], "summary": "Visoluten is an eye-tissue peptide mixture marketed for vision support in the Russian bioregulator tradition. Its retinal-targeting claim does not demonstrate selective delivery\u2026", "search_blob": "visoluten visoluten visoluten peptide retina bioregulator visoluten visoluten peptide retina bioregulator visoluten dosage visoluten dose visoluten research cognition longevity cognition longevity cognition longevity visoluten is an eye-tissue peptide mixture marketed for vision support in the russian bioregulator tradition. its retinal-targeting claim does not demonstrate selective delivery\u2026 one reader described using weaker reading glasses, while other accounts report little benefit, fading comfort or worse floaters. self-reported glasses strength does not prove a retinal change. visoluten is an eye-tissue peptide mixture marketed for vision support. reports include easier reading or less dryness, alongside little benefit, fading changes and worsening floaters; none establishes retinal repair. organ bioregulators peptide systemic systemic oral or lingual product with retina- or vision-targeted marketing; not a local eye treatment. systemic whole-body circulating", "legal_class": null }, { "id": 212, "slug": "thymogen", "name": "Thymogen", "aliases": [ "Thymogen peptide", "Glu-Trp dipeptide", "EW dipeptide" ], "type": "Peptide", "category": "Organ bioregulators", "goals_use_cases": [ "immune", "recovery" ], "delivery_methods": [ "nasal", "subcutaneous", "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "thymogen", "Thymogen peptide", "Glu-Trp dipeptide", "EW dipeptide", "thymogen dosage", "Thymogen dose", "immune", "recovery" ], "feel_search": [ "immune", "recovery" ], "summary": "Thymogen, also called oglufanide, is the synthetic Glu-Trp dipeptide derived from thymus-extract research and discussed for immune effects.", "search_blob": "thymogen thymogen thymogen peptide glu-trp dipeptide ew dipeptide thymogen thymogen peptide glu-trp dipeptide ew dipeptide thymogen dosage thymogen dose immune recovery immune recovery immune recovery thymogen, also called oglufanide, is the synthetic glu-trp dipeptide derived from thymus-extract research and discussed for immune effects. one person reported less food-triggered discomfort alongside substantial water retention and constipation. thymogen is synthetic glu-trp, also called oglufanide, discussed for immune-related symptoms and recovery. reports include easier eating or more energy, nonresponse and unwanted effects; oral blends cannot establish thymogen-only outcomes. organ bioregulators peptide systemic systemic immune-modulation discussion around a defined glu-trp dipeptide; route and product form vary. systemic whole-body circulating", "legal_class": null }, { "id": 213, "slug": "tuftsin", "name": "Tuftsin", "aliases": [ "Thr-Lys-Pro-Arg", "tuftsin tetrapeptide" ], "type": "Peptide", "category": "Immune / antimicrobial", "goals_use_cases": [ "immune", "recovery" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "tuftsin", "Thr-Lys-Pro-Arg", "tuftsin tetrapeptide", "tuftsin peptide", "tuftsin dosage", "Tuftsin dose", "immune", "recovery" ], "feel_search": [ "immune", "recovery" ], "summary": "Tuftsin is a natural four-amino-acid fragment of the immune protein IgG, studied for immune cells that engulf germs; Selank is a modified analogue.", "search_blob": "tuftsin tuftsin thr-lys-pro-arg tuftsin tetrapeptide tuftsin thr-lys-pro-arg tuftsin tetrapeptide tuftsin peptide tuftsin dosage tuftsin dose immune recovery immune recovery immune recovery tuftsin is a natural four-amino-acid fragment of the immune protein igg, studied for immune cells that engulf germs; selank is a modified analogue. the inspected community post discusses selank, with no direct tuftsin experience to summarize. tuftsin is a natural four-amino-acid immune peptide. the reviewed community reports concern selank, a modified relative, and do not establish what native tuftsin feels like. immune / antimicrobial peptide systemic endogenous immune-signaling tetrapeptide studied systemically by iv; no organ-specific capsule exposure or consumer injection pattern was established. systemic whole-body circulating", "legal_class": null }, { "id": 214, "slug": "resveratrol", "name": "Resveratrol", "aliases": [ "trans-resveratrol", "red-wine polyphenol" ], "type": "Non-peptide", "category": "Longevity & cellular energy", "goals_use_cases": [ "longevity", "cardiovascular", "recovery", "insulin sensitivity", "cognition" ], "delivery_methods": [ "oral", "sublingual" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "resveratrol", "trans-resveratrol", "red-wine polyphenol", "resveratrol peptide", "resveratrol dosage", "Resveratrol dose", "longevity", "cardiovascular", "recovery", "insulin sensitivity", "cognition" ], "feel_search": [ "longevity", "cardiovascular", "recovery", "insulin sensitivity", "cognition" ], "summary": "Resveratrol is a grape-associated plant polyphenol sold as an oral supplement and discussed for longevity.", "search_blob": "resveratrol resveratrol trans-resveratrol red-wine polyphenol resveratrol trans-resveratrol red-wine polyphenol resveratrol peptide resveratrol dosage resveratrol dose longevity cardiovascular recovery insulin sensitivity cognition longevity cardiovascular recovery insulin sensitivity cognition longevity cardiovascular recovery insulin sensitivity cognition resveratrol is a grape-associated plant polyphenol sold as an oral supplement and discussed for longevity. some users describe subtle thinking, exercise or sleep changes, while others notice no benefit. one nmn/tmg/resveratrol user initially felt unwell and still reported no energy benefit after changes; the combination prevents isolating resveratrol. resveratrol is a plant polyphenol sold as a supplement and discussed for longevity. reports include subtle cognitive, exercise or sleep changes, but also no benefit, stomach discomfort and other adverse symptoms. longevity & cellular energy non-peptide systemic systemic oral polyphenol (bioavailability-limited). systemic whole-body circulating", "legal_class": null }, { "id": 215, "slug": "tadalafil", "name": "Tadalafil", "aliases": [ "Cialis", "Cialis Daily", "the weekend pill", "generic Cialis", "Adcirca (PAH brand, 20 mg tablet / 40 mg daily talk)", "Alyq (PAH generic brand talk)", "Tadalafil citrate (forum chemistry shorthand \u2014 commercial salt is not always specified)", "Daily Cialis / daily tad", "Tad / tada (forum shorthand)" ], "type": "Non-peptide", "category": "Sexual / reproductive", "goals_use_cases": [ "libido", "performance", "TRT-adjacent sexual function", "libido / erectile function (discussed)", "morning wood / spontaneous erection quality (community)", "BPH / urinary flow (labeled daily-use talk)", "gym pumps / vascularity (community)", "blood-pressure / endothelial talk (community)", "endurance / workout flush (community)", "Peyronie's / post-prostate recovery narratives", "performance continuity", "longevity / endothelial-health halo (biohacker rooms)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "tadalafil", "cialis", "cialas", "cialus", "tadalafill", "tadalafil 5mg", "daily cialis", "weekend pill", "adcirca", "generic cialis", "pumps", "back pain", "back pumps", "morning wood", "stuffy nose", "harder erections", "heartburn" ], "feel_search": [ "pumps", "back pain", "back pumps", "morning wood", "stuffy nose", "weekend pill", "harder erections", "heartburn" ], "summary": "Tadalafil is a long-acting oral PDE5 inhibitor used in medicines for erectile dysfunction, prostate symptoms and pulmonary hypertension.", "search_blob": "tadalafil tadalafil cialis cialis daily the weekend pill generic cialis adcirca (pah brand, 20 mg tablet / 40 mg daily talk) alyq (pah generic brand talk) tadalafil citrate (forum chemistry shorthand \u2014 commercial salt is not always specified) daily cialis / daily tad tad / tada (forum shorthand) tadalafil cialis cialas cialus tadalafill tadalafil 5mg daily cialis weekend pill adcirca generic cialis pumps back pain back pumps morning wood stuffy nose harder erections heartburn libido performance trt-adjacent sexual function libido / erectile function (discussed) morning wood / spontaneous erection quality (community) bph / urinary flow (labeled daily-use talk) gym pumps / vascularity (community) blood-pressure / endothelial talk (community) endurance / workout flush (community) peyronie's / post-prostate recovery narratives performance continuity longevity / endothelial-health halo (biohacker rooms) pumps back pain back pumps morning wood stuffy nose weekend pill harder erections heartburn tadalafil is a long-acting oral pde5 inhibitor used in medicines for erectile dysfunction, prostate symptoms and pulmonary hypertension. one user reported improved erections but worsening back pain that led them to stop; replies describe different tolerability. tadalafil is a long-acting oral pde5 inhibitor used for erectile dysfunction and other indication-specific medical purposes. people report steadier erections and gym pumps, but headaches, reflux, congestion or muscle pain can outweigh the benefit. it supports the erection response rather than supplying testosterone. pain and reflux sometimes persist or begin after months of use. sexual / reproductive non-peptide systemic systemic oral pde5 inhibitor \u2014 whole-body vasodilation with a sexual-function and prostate story in the same threads. systemic whole-body circulating", "legal_class": null }, { "id": 216, "slug": "minoxidil", "name": "Minoxidil", "aliases": [ "Rogaine", "Loniten", "LDOM", "oral minox", "Regaine (UK/EU brand talk)", "Loniten (oral hypertension brand)", "LDOM / low-dose oral minoxidil", "oral minox / OM", "topical minox", "minoxidil 5%", "minoxidil foam", "Kirkland minoxidil (generic foam/liquid talk)" ], "type": "Non-peptide", "category": "Skin, hair & tissue remodeling", "goals_use_cases": [ "skin/hair", "androgenetic alopecia", "androgenetic alopecia / temple and crown (discussed)", "beard fill-in (topical community)", "body-hair / hypertrichosis as a wanted or unwanted effect", "shedding control (after the dread-shed window)", "vasodilator / blood-pressure history (original drug job)", "eyebrow / lash crossover (minority topical)" ], "delivery_methods": [ "topical", "oral" ], "discussion_popularity": "High", "reach": "Mixed", "misspellings_search_terms": [ "minoxidil", "minoxodil", "minox", "rogaine", "regaine", "loniten", "oral minoxidil", "ldom", "minoxidil 5%", "dread shed", "oral vs topical", "switch shed", "puffy face", "palpitations", "beard minox", "body hair", "itchy scalp", "ankle swelling", "baby hairs", "cats minoxidil" ], "feel_search": [ "dread shed", "puffy face", "palpitations", "beard minox", "body hair", "itchy scalp", "ankle swelling", "baby hairs", "oral vs topical", "switch shed", "cats minoxidil" ], "summary": "Minoxidil is a vasodilator used topically or in low-dose oral prescriptions for hair growth; oral and topical effects differ.", "search_blob": "minoxidil minoxidil rogaine loniten ldom oral minox regaine (uk/eu brand talk) loniten (oral hypertension brand) ldom / low-dose oral minoxidil oral minox / om topical minox minoxidil 5% minoxidil foam kirkland minoxidil (generic foam/liquid talk) minoxidil minoxodil minox rogaine regaine loniten oral minoxidil ldom minoxidil 5% dread shed oral vs topical switch shed puffy face palpitations beard minox body hair itchy scalp ankle swelling baby hairs cats minoxidil skin/hair androgenetic alopecia androgenetic alopecia / temple and crown (discussed) beard fill-in (topical community) body-hair / hypertrichosis as a wanted or unwanted effect shedding control (after the dread-shed window) vasodilator / blood-pressure history (original drug job) eyebrow / lash crossover (minority topical) dread shed puffy face palpitations beard minox body hair itchy scalp ankle swelling baby hairs oral vs topical switch shed cats minoxidil minoxidil is a vasodilator used topically or in low-dose oral prescriptions for hair growth; oral and topical effects differ. topical users may notice scalp irritation; oral users may feel nothing or report puffiness or a faster pulse. an early shed can precede visible changes over months. minoxidil is a hair-growth medicine used on the scalp or discussed as oral tablets. reports include fuller hair, little change, prolonged shedding and unwanted body hair. oral reports at 1.25, 2.5 and 5 mg vary in benefit and unwanted effects; these are reported amounts, not a dose ladder. skin, hair & tissue remodeling non-peptide mixed topical products are applied to the scalp but can have systemic effects; oral tablets produce systemic exposure. mixed local systemic", "legal_class": null }, { "id": 217, "slug": "dutasteride", "name": "Dutasteride", "aliases": [ "Avodart", "dut", "dut 0.5", "dual 5-AR inhibitor", "Jalyn (dutasteride + tamsulosin combo talk)", "Avolve / Zyfotir (regional brand talk)" ], "type": "Non-peptide", "category": "Skin, hair & tissue remodeling", "goals_use_cases": [ "skin/hair", "androgenetic alopecia", "BPH", "androgenetic alopecia / DHT-blockade discussions", "BPH / urinary symptoms", "comparisons after finasteride", "shedding during treatment changes (reported)", "TRT-adjacent DHT discussion (contested)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "dutasteride", "dutasteride 0.5", "avodart", "avodart hair", "dutasterid", "dutas", "dual 5ar", "dut vs fin", "mesotherapy", "2x week dut", "3x week dut", "topical dut", "allopregnanolone", "skin/hair", "androgenetic alopecia / DHT blockade (off-label US)", "BPH / urinary (labeled 0.5 mg)", "finasteride non-responder step-up", "shedding control (after the switch shed)", "TRT-adjacent DHT talk (minority, contested)", "watery semen", "no libido", "switch shed", "brain fog", "nipple sensitivity", "morning wood gone", "2x week", "3x week" ], "feel_search": [ "watery semen", "no libido", "switch shed", "dut vs fin", "brain fog", "nipple sensitivity", "morning wood gone", "mesotherapy", "2x week", "3x week", "allopregnanolone", "topical dut" ], "summary": "Dutasteride (Avodart) blocks both main 5-alpha-reductase types, reducing DHT; it is used for prostate enlargement and discussed for hair loss.", "search_blob": "dutasteride dutasteride avodart dut dut 0.5 dual 5-ar inhibitor jalyn (dutasteride + tamsulosin combo talk) avolve / zyfotir (regional brand talk) dutasteride dutasteride 0.5 avodart avodart hair dutasterid dutas dual 5ar dut vs fin mesotherapy 2x week dut 3x week dut topical dut allopregnanolone skin/hair androgenetic alopecia / dht blockade (off-label us) bph / urinary (labeled 0.5 mg) finasteride non-responder step-up shedding control (after the switch shed) trt-adjacent dht talk (minority, contested) watery semen no libido switch shed brain fog nipple sensitivity morning wood gone 2x week 3x week skin/hair androgenetic alopecia bph androgenetic alopecia / dht-blockade discussions bph / urinary symptoms comparisons after finasteride shedding during treatment changes (reported) trt-adjacent dht discussion (contested) watery semen no libido switch shed dut vs fin brain fog nipple sensitivity morning wood gone mesotherapy 2x week 3x week allopregnanolone topical dut dutasteride (avodart) blocks both main 5-alpha-reductase types, reducing dht; it is used for prostate enlargement and discussed for hair loss. reports range from thicker hair to continued thinning and sexual or mood complaints. one finasteride switcher describes many months of shedding before possible new hairs, with minoxidil and microneedling complicating attribution. dutasteride reduces dht and is used for enlarged prostate and discussed for hair loss. reports range from thicker hair to continued thinning and sexual or mood complaints. its roughly five-week steady-state half-life describes blood elimination, not the timing of regrowth or recovery from adverse symptoms. skin, hair & tissue remodeling non-peptide systemic systemic oral dual 5-alpha-reductase inhibitor that reduces serum and scalp dht. systemic whole-body circulating", "legal_class": null }, { "id": 218, "slug": "anastrozole", "name": "Anastrozole", "aliases": [ "Arimidex", "Adex", "aromatase inhibitor", "AI / aromatase inhibitor (when they mean this one)", "anastrozole 1 mg", "Arimidex microdose" ], "type": "Non-peptide", "category": "Hormone modulators", "goals_use_cases": [ "hormone axis", "estradiol control", "estradiol control on TRT / AAS (discussed)", "nipple sensitivity / gyno scare (community)", "water retention / bloat (high-E2 talk)", "libido (both high-E2 and crashed-E2 stories)", "fertility / T:E2 ratio (clinic-adjacent)", "breast-cancer label (1 mg daily in women \u2014 not the TRT card)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "anastrozole", "anastrazole", "arimidex", "arimidex 0.25", "adex", "aromatase inhibitor", "crashed e2", "high e2 trt", "low shbg", "0.125 anastrozole", "as needed ai", "sensitive e2", "dry joints", "no libido", "nipple sensitivity", "water retention", "high e2", "mood crash", "no morning wood", "0.125" ], "feel_search": [ "crashed e2", "dry joints", "no libido", "nipple sensitivity", "water retention", "high e2", "mood crash", "no morning wood", "low shbg", "as needed ai", "sensitive e2", "0.125" ], "summary": "Anastrozole (Arimidex) is an oral aromatase inhibitor that reduces production of estradiol from androgens.", "search_blob": "anastrozole anastrozole arimidex adex aromatase inhibitor ai / aromatase inhibitor (when they mean this one) anastrozole 1 mg arimidex microdose anastrozole anastrazole arimidex arimidex 0.25 adex aromatase inhibitor crashed e2 high e2 trt low shbg 0.125 anastrozole as needed ai sensitive e2 dry joints no libido nipple sensitivity water retention high e2 mood crash no morning wood 0.125 hormone axis estradiol control estradiol control on trt / aas (discussed) nipple sensitivity / gyno scare (community) water retention / bloat (high-e2 talk) libido (both high-e2 and crashed-e2 stories) fertility / t:e2 ratio (clinic-adjacent) breast-cancer label (1 mg daily in women \u2014 not the trt card) crashed e2 dry joints no libido nipple sensitivity water retention high e2 mood crash no morning wood low shbg as needed ai sensitive e2 0.125 anastrozole (arimidex) is an oral aromatase inhibitor that reduces production of estradiol from androgens. a trt account describes brief initial symptom improvement followed by a delayed low-estrogen-like slump. symptoms alone did not reliably identify the hormone problem. anastrozole (arimidex) is an oral aromatase inhibitor that reduces estrogen production. trt accounts describe symptom relief, nonresponse and unwanted mood, joint or sexual effects; feelings alone cannot identify estradiol status. accounts describe adverse symptoms even after 0.25 mg. dry joints and low libido are reported, but those feelings alone do not establish that estradiol was driven too low. hormone modulators non-peptide systemic systemic oral non-steroidal aromatase inhibitor \u2014 whole-body estradiol production drops. systemic whole-body circulating", "legal_class": null }, { "id": 219, "slug": "melatonin", "name": "Melatonin", "aliases": [ "melatonin gummy", "microdose melatonin", "injectable melatonin", "N-acetyl-5-methoxytryptamine", "circadian hormone", "time-release melatonin / Circadin-class (2 mg PR talk)", "injectable melatonin (research-chem / marketplace vials)", "microdose melatonin (0.3 mg talk)" ], "type": "Non-peptide", "category": "Sleep / mood", "goals_use_cases": [ "sleep", "jet lag", "sleep onset / jet lag (discussed)", "vivid dreams / REM talk", "circadian shift (night-owl / shift-work)", "recovery / next-day grogginess (the downside people chase away)", "high-dose antioxidant / immune halo (community, thinner)", "stack with DSIP / apigenin / magnesium (Huberman-adjacent)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "melatonin", "melatonine", "melatonin 0.3", "melatonin 10mg", "melatonin gummy", "injectable melatonin", "huberman melatonin", "groggy", "vivid dreams", "hangover", "jet lag", "3am wake", "head movies", "can't fall asleep" ], "feel_search": [ "groggy", "vivid dreams", "hangover", "jet lag", "3am wake", "head movies", "can't fall asleep" ], "summary": "Melatonin is a hormone that signals biological night, sold in sleep supplements and used for body-clock timing rather than guaranteed sedation.", "search_blob": "melatonin melatonin melatonin gummy microdose melatonin injectable melatonin n-acetyl-5-methoxytryptamine circadian hormone time-release melatonin / circadin-class (2 mg pr talk) injectable melatonin (research-chem / marketplace vials) microdose melatonin (0.3 mg talk) melatonin melatonine melatonin 0.3 melatonin 10mg melatonin gummy injectable melatonin huberman melatonin groggy vivid dreams hangover jet lag 3am wake head movies can't fall asleep sleep jet lag sleep onset / jet lag (discussed) vivid dreams / rem talk circadian shift (night-owl / shift-work) recovery / next-day grogginess (the downside people chase away) high-dose antioxidant / immune halo (community, thinner) stack with dsip / apigenin / magnesium (huberman-adjacent) groggy vivid dreams hangover jet lag 3am wake head movies can't fall asleep melatonin is a hormone that signals biological night, sold in sleep supplements and used for body-clock timing rather than guaranteed sedation. it may help sleep without producing a strong sleepy feeling. in the reviewed thread, one person slept better with sleep-habit changes, while others reported next-day grogginess or early awakening. melatonin is a nighttime hormone used for sleep timing. accounts include better sleep without strong sleepiness, no benefit, early waking and next-day grogginess. the reviewed experience accounts mainly concern oral products; advertised 10 mg research vials do not establish a human injection dose. sleep / mood non-peptide systemic systemic \u2014 pineal hormone (an indoleamine, not a peptide). systemic whole-body circulating", "legal_class": null }, { "id": 220, "slug": "teriparatide", "name": "Teriparatide", "aliases": [ "Forteo", "PTH 1-34", "Forsteo (EU brand talk)", "recombinant PTH(1-34)", "generic teriparatide / Teva pen", "Bonsity (follow-on teriparatide talk)" ], "type": "Peptide", "category": "Growth factors", "goals_use_cases": [ "bone density", "osteoporosis", "follow-on treatment discussions", "bone density / osteoporosis", "fracture-risk discussions", "bone-building and follow-on treatment", "longevity claims (unverified)", "glucocorticoid-related osteoporosis discussions", "post-teriparatide comparisons: Prolia / Reclast / alendronate" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "teriparatide", "teraparatide", "forteo", "forsteo", "pth 1-34", "forteo pen", "bone peptide", "bone density / osteoporosis (labeled)", "fracture-risk talk (high-risk spine)", "anabolic bone build then antiresorptive lock-in", "longevity / Huberman 75+ bone-peptide teaser", "glucocorticoid or very-low-T-score rescue narratives", "post-Forteo \u201cwhat do I take next\u201d (Prolia / Reclast / alendronate)", "bone density", "longevity", "bone pain", "nausea after pin", "lightheaded", "fridge pen", "next dexa", "osteosarcoma" ], "feel_search": [ "bone pain", "nausea after pin", "lightheaded", "fridge pen", "next dexa", "osteosarcoma" ], "summary": "Teriparatide is PTH(1-34), a prescription bone-building medicine. Patients report improved scans, little change and varied symptoms; immediate sensations do not measure bone\u2026", "search_blob": "teriparatide teriparatide forteo pth 1-34 forsteo (eu brand talk) recombinant pth(1-34) generic teriparatide / teva pen bonsity (follow-on teriparatide talk) teriparatide teraparatide forteo forsteo pth 1-34 forteo pen bone peptide bone density / osteoporosis (labeled) fracture-risk talk (high-risk spine) anabolic bone build then antiresorptive lock-in longevity / huberman 75+ bone-peptide teaser glucocorticoid or very-low-t-score rescue narratives post-forteo \u201cwhat do i take next\u201d (prolia / reclast / alendronate) bone density longevity bone pain nausea after pin lightheaded fridge pen next dexa osteosarcoma bone density osteoporosis follow-on treatment discussions bone density / osteoporosis fracture-risk discussions bone-building and follow-on treatment longevity claims (unverified) glucocorticoid-related osteoporosis discussions post-teriparatide comparisons: prolia / reclast / alendronate bone pain nausea after pin lightheaded fridge pen next dexa osteosarcoma teriparatide is pth(1-34), a prescription bone-building medicine. patients report improved scans, little change and varied symptoms; immediate sensations do not measure bone\u2026 some osteoporosis patients report little discomfort; others describe early, persistent or returning nausea, headache, bruising or pain. bone-density results also vary and must be assessed separately from symptoms. teriparatide is pth(1-34), a prescription bone-building medicine. patients report improved scans, little change and varied symptoms; immediate sensations do not measure bone response. some patients notice little discomfort; others report early, persistent or returning nausea, pain or dizziness. symptoms and scan outcomes are separate. growth factors peptide systemic systemic daily pth(1-34) pulse aimed at bone formation. systemic whole-body circulating", "legal_class": null }, { "id": 221, "slug": "abaloparatide", "name": "Abaloparatide", "aliases": [ "Tymlos", "PTHrP analog", "BA058 (development code talk)", "abaloparatide 80 mcg" ], "type": "Peptide", "category": "Growth factors", "goals_use_cases": [ "bone density", "bone density / osteoporosis (labeled)", "spine T-score talk", "Forteo alternative (room-temp pen, side-effect shop)", "Huberman-class bone-peptide search", "post-course antiresorptive lock-in" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "abaloparatide", "aloparatide", "tymlos", "tylos", "pthrp", "tymlos 80", "injection sting", "dizzy after shot", "hair shedding", "room temperature pen", "tymlos vs forteo" ], "feel_search": [ "injection sting", "dizzy after shot", "hair shedding", "room temperature pen", "tymlos vs forteo" ], "summary": "Abaloparatide (Tymlos) is a daily injectable PTHrP analogue used for osteoporosis. Patients compare scan changes and treatment burden; a brief sensation after injection does not\u2026", "search_blob": "abaloparatide abaloparatide tymlos pthrp analog ba058 (development code talk) abaloparatide 80 mcg abaloparatide aloparatide tymlos tylos pthrp tymlos 80 injection sting dizzy after shot hair shedding room temperature pen tymlos vs forteo bone density bone density / osteoporosis (labeled) spine t-score talk forteo alternative (room-temp pen, side-effect shop) huberman-class bone-peptide search post-course antiresorptive lock-in injection sting dizzy after shot hair shedding room temperature pen tymlos vs forteo abaloparatide (tymlos) is a daily injectable pthrp analogue used for osteoporosis. patients compare scan changes and treatment burden; a brief sensation after injection does not\u2026 some patients describe a brief racing heart or headache after injections. bone-density improvement is a longer-term outcome rather than a same-day sensation. abaloparatide (tymlos) is a daily injectable pthrp analogue used for osteoporosis. patients compare scan changes and treatment burden; a brief sensation after injection does not show bone improvement. the opened pen's storage can make travel easier. reports range from no systemic symptoms to racing heart, headache, nausea or more persistent problems, without a reliable tolerability ranking against forteo. growth factors peptide systemic systemic daily pthrp-analog pulse for bone formation. systemic whole-body circulating", "legal_class": null }, { "id": 222, "slug": "follitropin-alfa", "name": "rFSH (Follitropin alfa)", "aliases": [ "Gonal-F", "recombinant FSH", "follitropin alfa", "Gonal-f RFF / Gonal-f pen", "Follistim / follitropin beta (sister product, not identical)", "Puregon (beta, regional)", "Foligraf (regional rFSH kit talk)" ], "type": "Peptide", "category": "Sexual / reproductive", "goals_use_cases": [ "fertility", "hormone support", "fertility / spermatogenesis on or after TRT", "testicular volume (with hCG)", "hypogonadotropic hypogonadism (labeled male use)", "IVF / ovulation induction (labeled female use \u2014 different IU world)", "Tatem-style \u201cFSH + hCG if you want kids on TRT\u201d" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "rfsh", "r-fsh", "gonal-f", "gonal f", "follitropin", "follitropin alfa", "follistim", "puregon", "gonal", "zero sperm", "azoospermia", "testicular volume", "want kids on trt" ], "feel_search": [ "zero sperm", "azoospermia", "testicular volume", "gonal", "want kids on trt" ], "summary": "Follitropin alfa is manufactured FSH, the fertility hormone in Gonal-F; men discuss it when sperm production remains low despite hCG.", "search_blob": "rfsh (follitropin alfa) follitropin-alfa gonal-f recombinant fsh follitropin alfa gonal-f rff / gonal-f pen follistim / follitropin beta (sister product, not identical) puregon (beta, regional) foligraf (regional rfsh kit talk) rfsh r-fsh gonal-f gonal f follitropin follitropin alfa follistim puregon gonal zero sperm azoospermia testicular volume want kids on trt fertility hormone support fertility / spermatogenesis on or after trt testicular volume (with hcg) hypogonadotropic hypogonadism (labeled male use) ivf / ovulation induction (labeled female use \u2014 different iu world) tatem-style \u201cfsh + hcg if you want kids on trt\u201d zero sperm azoospermia testicular volume gonal want kids on trt follitropin alfa is manufactured fsh, the fertility hormone in gonal-f; men discuss it when sperm production remains low despite hcg. no dependable immediate beneficial sensation is established in these accounts. injection soreness or bruising may be noticeable; male fertility response is followed with semen testing over months. follitropin alfa is recombinant fsh used in fertility treatment. male reports track sperm counts and movement over months, with partial improvement and unresolved outcomes. reports at 75\u2013150 iu use differing frequencies and co-treatments. semen results do not establish pregnancy, and hmg is a different product. sexual / reproductive peptide systemic systemic glycoprotein hormone (recombinant fsh). systemic whole-body circulating", "legal_class": null }, { "id": 223, "slug": "eloralintide", "name": "Eloralintide", "aliases": [ "LY3841136", "Elo", "Elo / Elora (forum shorthand)", "Lilly selective amylin", "SARA (selective amylin receptor agonist talk)" ], "type": "Peptide", "category": "Metabolic / GLP-1 class", "goals_use_cases": [ "fat loss", "appetite control", "fat loss / obesity research", "appetite and amylin signaling", "combinations with tirzepatide (research)", "cagrilintide / CagriSema comparison", "comparisons with retatrutide" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "eloralintide", "ly3841136", "elora", "elo peptide", "lilly amylin", "fat loss / obesity (Phase 2)", "appetite / amylin satiety (less GLP-nausea story)", "add-on to tirzepatide (Phase 1b combo talk)", "cagrilintide / CagriSema comparison", "gray-vial \u201cnext after reta\u201d shopping", "amylin nausea", "less vomit than glp", "elo vial", "cagrisema alternative" ], "feel_search": [ "amylin nausea", "less vomit than glp", "elo vial", "cagrisema alternative" ], "summary": "Eloralintide (LY3841136) is an investigational long-acting selective amylin agonist studied as a weekly injection for weight management.", "search_blob": "eloralintide eloralintide ly3841136 elo elo / elora (forum shorthand) lilly selective amylin sara (selective amylin receptor agonist talk) eloralintide ly3841136 elora elo peptide lilly amylin fat loss / obesity (phase 2) appetite / amylin satiety (less glp-nausea story) add-on to tirzepatide (phase 1b combo talk) cagrilintide / cagrisema comparison gray-vial \u201cnext after reta\u201d shopping amylin nausea less vomit than glp elo vial cagrisema alternative fat loss appetite control fat loss / obesity research appetite and amylin signaling combinations with tirzepatide (research) cagrilintide / cagrisema comparison comparisons with retatrutide amylin nausea less vomit than glp elo vial cagrisema alternative eloralintide (ly3841136) is an investigational long-acting selective amylin agonist studied as a weekly injection for weight management. a gray-market account describes delayed nausea; a separate blinded trial participant reports less food preoccupation. unknown products or treatment arms limit both accounts. eloralintide is an investigational amylin peptide studied for weight management. reports include less appetite or food preoccupation, but also delayed nausea, fatigue, uncomfortable fullness, plateaus and little change. week 1 experiences vary; the small, selected n=1 record does not establish how often nausea occurs or when a benefit should appear. metabolic / glp-1 class peptide systemic systemic once-weekly selective amylin receptor agonist. systemic whole-body circulating", "legal_class": null }, { "id": 224, "slug": "petrelintide", "name": "Petrelintide", "aliases": [ "ZP8396", "Zealand amylin", "Roche / Zealand amylin analog", "pertrelintide (common misspelling in press)" ], "type": "Peptide", "category": "Metabolic / GLP-1 class", "goals_use_cases": [ "fat loss", "fat loss / obesity (Phase 2)", "\u201cGLP nausea-lite\u201d amylin story", "future combo with enicepatide / CT-388 (Roche talk)", "cagrilintide / eloralintide comparison" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "petrelintide", "pertrelintide", "zp8396", "zealand amylin", "roche amylin", "placebo like gi", "amylin without vomit", "zupreme", "10 percent but stay on it" ], "feel_search": [ "placebo like gi", "amylin without vomit", "zupreme", "10 percent but stay on it" ], "summary": "Petrelintide (ZP8396) is an investigational long-acting amylin analogue studied for weight management.", "search_blob": "petrelintide petrelintide zp8396 zealand amylin roche / zealand amylin analog pertrelintide (common misspelling in press) petrelintide pertrelintide zp8396 zealand amylin roche amylin placebo like gi amylin without vomit zupreme 10 percent but stay on it fat loss fat loss / obesity (phase 2) \u201cglp nausea-lite\u201d amylin story future combo with enicepatide / ct-388 (roche talk) cagrilintide / eloralintide comparison placebo like gi amylin without vomit zupreme 10 percent but stay on it petrelintide (zp8396) is an investigational long-acting amylin analogue studied for weight management. the inspected discussion compares trial results and tolerability hopes; it does not provide a petrelintide user's felt timeline. petrelintide (zp8396) is an investigational long-acting amylin analogue for weight management. discussion weighs trial weight loss against tolerability; it does not establish a verified personal appetite timeline. the detailed weight-loss and adverse-effect diary in the amylin comparison thread concerns eloralintide, not petrelintide. metabolic / glp-1 class peptide systemic systemic once-weekly long-acting amylin analog (zealand, partnered with roche). systemic whole-body circulating", "legal_class": null }, { "id": 225, "slug": "enicepatide", "name": "Enicepatide", "aliases": [ "CT-388", "RO7795068", "CT388", "RG6640", "Roche / Carmot dual GLP-1/GIP" ], "type": "Peptide", "category": "Metabolic / GLP-1 class", "goals_use_cases": [ "fat loss", "fat loss / obesity (Phase 2 ~23%)", "tirzepatide-class dual agonist comparison", "planned combo with petrelintide", "T2D obesity (separate Phase 2)" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "enicepatide", "encipetide", "ct-388", "ct388", "ro7795068", "carmot dual", "another tirz", "roche dual", "food noise" ], "feel_search": [ "another tirz", "ct-388", "roche dual", "food noise" ], "summary": "Enicepatide (CT-388) is an investigational dual GLP-1/GIP peptide injection being studied for weight management.", "search_blob": "enicepatide enicepatide ct-388 ro7795068 ct388 rg6640 roche / carmot dual glp-1/gip enicepatide encipetide ct-388 ct388 ro7795068 carmot dual another tirz roche dual food noise fat loss fat loss / obesity (phase 2 ~23%) tirzepatide-class dual agonist comparison planned combo with petrelintide t2d obesity (separate phase 2) another tirz ct-388 roche dual food noise enicepatide (ct-388) is an investigational dual glp-1/gip peptide injection being studied for weight management. the inspected post is a request to meet trial participants. it contains no substantive use report, so it cannot supply a personal appetite or side-effect timeline. enicepatide is an investigational glp-1/gip peptide studied for weight management. the reviewed community posts discuss trials and future options, without establishing firsthand effects. the reviewed posts do not establish personal onset, duration, nonresponse or adverse-effect timelines. metabolic / glp-1 class peptide systemic systemic once-weekly biased dual glp-1/gip agonist (carmot \u2192 roche). systemic whole-body circulating", "legal_class": null }, { "id": 226, "slug": "aleniglipron", "name": "Aleniglipron", "aliases": [ "GSBR-1290", "Structure Therapeutics oral GLP-1", "aleniglipron pill" ], "type": "Non-peptide", "category": "Metabolic / GLP-1 class", "goals_use_cases": [ "fat loss", "appetite control", "oral GLP-1 research", "orforglipron comparison", "oral versus injected medicines", "clinical-development updates" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "aleniglipron", "gsbr-1290", "gsbr1290", "structure oral glp", "fat loss without a pin", "orforglipron comparison (the other oral small-molecule GLP-1)", "needle-averse GLP-1 access talk", "Phase 3 2H 2026 watch", "oral glp vomit", "pill not rybelsus", "orforglipron alternative" ], "feel_search": [ "oral glp vomit", "pill not rybelsus", "orforglipron alternative" ], "summary": "Aleniglipron (GSBR-1290) is an investigational non-peptide GLP-1 tablet being developed for weight management.", "search_blob": "aleniglipron aleniglipron gsbr-1290 structure therapeutics oral glp-1 aleniglipron pill aleniglipron gsbr-1290 gsbr1290 structure oral glp fat loss without a pin orforglipron comparison (the other oral small-molecule glp-1) needle-averse glp-1 access talk phase 3 2h 2026 watch oral glp vomit pill not rybelsus orforglipron alternative fat loss appetite control oral glp-1 research orforglipron comparison oral versus injected medicines clinical-development updates oral glp vomit pill not rybelsus orforglipron alternative aleniglipron (gsbr-1290) is an investigational non-peptide glp-1 tablet being developed for weight management. the inspected community thread discusses a future oral option, not firsthand use. appetite and nausea timelines should come from its trials, not other glp-1 drugs. aleniglipron is an investigational oral drug studied for weight management. appetite, stomach-emptying and glucose effects explain the interest; they do not supply a firsthand experience timeline. later 2.5 mg starting cohorts are a tolerability discussion, not a personal dose lesson; phase 3 is underway, not approval. metabolic / glp-1 class non-peptide systemic systemic once-daily oral small-molecule glp-1 agonist. systemic whole-body circulating", "legal_class": null }, { "id": 227, "slug": "ribupatide", "name": "Ribupatide", "aliases": [ "HRS-9531", "KAI-9531", "HRS9531", "Kailera / Hengrui dual GLP-1/GIP", "ribupatide oral", "ribupatide injection" ], "type": "Peptide", "category": "Metabolic / GLP-1 class", "goals_use_cases": [ "fat loss", "fat loss / obesity (China Phase 3 + global Phase 3)", "tirzepatide-class dual comparison", "oral dual-agonist curiosity", "gray \u201cChina tirz\u201d shopping (identity risk)" ], "delivery_methods": [ "subcutaneous", "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "ribupatide", "hrs-9531", "hrs9531", "kai-9531", "kailera", "hengrui dual", "china tirz", "oral dual" ], "feel_search": [ "china tirz", "hrs9531", "kailera", "oral dual" ], "summary": "Ribupatide (HRS-9531/KAI-9531) is an investigational dual-receptor agonist for weight management, developed in injectable and oral forms.", "search_blob": "ribupatide ribupatide hrs-9531 kai-9531 hrs9531 kailera / hengrui dual glp-1/gip ribupatide oral ribupatide injection ribupatide hrs-9531 hrs9531 kai-9531 kailera hengrui dual china tirz oral dual fat loss fat loss / obesity (china phase 3 + global phase 3) tirzepatide-class dual comparison oral dual-agonist curiosity gray \u201cchina tirz\u201d shopping (identity risk) china tirz hrs9531 kailera oral dual ribupatide (hrs-9531/kai-9531) is an investigational dual-receptor agonist for weight management, developed in injectable and oral forms. a trial participant later said they felt good, but their blinded assignment did not establish that they received ribupatide. ribupatide is an investigational dual glp-1/gip peptide developed as weekly injections and separate daily tablets. blinded accounts report weight or appetite changes and digestive symptoms, but do not confirm which treatment caused them. the trial percentages belong to different formulations, amounts and follow-up periods. a research-vial label does not identify the studied drug. metabolic / glp-1 class peptide systemic systemic dual glp-1/gip \u2014 weekly injection (kainetic / china phase 3) and a separate once-daily oral program. systemic whole-body circulating", "legal_class": null }, { "id": 228, "slug": "berobenatide", "name": "Berobenatide", "aliases": [ "MET-097i", "Pfizer monthly GLP-1", "PF-08653944", "PF\u20193944", "MET-097i (Metsera name before Pfizer)" ], "type": "Peptide", "category": "Metabolic / GLP-1 class", "goals_use_cases": [ "fat loss", "fat loss / obesity", "monthly instead of weekly GLP-1 talk", "Pfizer obesity comeback after danuglipron" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "berobenatide", "met-097i", "met097", "pfizer monthly glp", "pf3944", "monthly shot", "one injection a month", "vesper", "pfizer glp" ], "feel_search": [ "monthly shot", "one injection a month", "vesper", "pfizer glp" ], "summary": "Berobenatide (MET-097i) is an investigational long-acting GLP-1 peptide studied in weekly and monthly injection programs.", "search_blob": "berobenatide berobenatide met-097i pfizer monthly glp-1 pf-08653944 pf\u20193944 met-097i (metsera name before pfizer) berobenatide met-097i met097 pfizer monthly glp pf3944 monthly shot one injection a month vesper pfizer glp fat loss fat loss / obesity monthly instead of weekly glp-1 talk pfizer obesity comeback after danuglipron monthly shot one injection a month vesper pfizer glp berobenatide (met-097i) is an investigational long-acting glp-1 peptide studied in weekly and monthly injection programs. a relayed blinded-trial account describes less food noise, early fullness and occasional heartburn over five weeks. the participant did not know their treatment assignment. berobenatide is an investigational long-acting glp-1 peptide. reports discuss fewer injections, appetite changes and difficult food intake, but participant assignment and doses remain unverified. one diary describes a weekly-to-monthly trial transition, with differing reactions in replies. it does not establish a verified monthly effect curve. metabolic / glp-1 class peptide systemic systemic ultra-long glp-1 peptide \u2014 weekly titration then monthly maintenance in vesper. systemic whole-body circulating", "legal_class": null }, { "id": 229, "slug": "pyrilutamide", "name": "Pyrilutamide", "aliases": [ "KX-826", "KX826", "Kintor topical AR antagonist", "pyrilutamide 0.5%", "pyrilutamide 1%" ], "type": "Non-peptide", "category": "Skin, hair & tissue remodeling", "goals_use_cases": [ "skin/hair", "androgenetic alopecia / topical anti-androgen research", "side-effect comparisons with finasteride and dutasteride", "RU-58841 comparison", "shedding and itch reports", "combinations with minoxidil" ], "delivery_methods": [ "topical" ], "discussion_popularity": "Medium", "reach": "Local", "misspellings_search_terms": [ "pyrilutamide", "pyrilutimide", "kx-826", "kx826", "kintor", "kx 826", "androgenetic alopecia / topical anti-androgen", "fin/dut side-effect escape", "RU-58841 comparison", "shed control / itch (community)", "add-on to minoxidil", "scalp itch gone", "kx shed", "nipple sensitivity", "better than ru", "topical antiandrogen" ], "feel_search": [ "scalp itch gone", "kx shed", "nipple sensitivity", "better than ru", "topical antiandrogen" ], "summary": "Pyrilutamide (KX-826) is a topical androgen-receptor blocker studied for hair loss.", "search_blob": "pyrilutamide pyrilutamide kx-826 kx826 kintor topical ar antagonist pyrilutamide 0.5% pyrilutamide 1% pyrilutamide pyrilutimide kx-826 kx826 kintor kx 826 androgenetic alopecia / topical anti-androgen fin/dut side-effect escape ru-58841 comparison shed control / itch (community) add-on to minoxidil scalp itch gone kx shed nipple sensitivity better than ru topical antiandrogen skin/hair androgenetic alopecia / topical anti-androgen research side-effect comparisons with finasteride and dutasteride ru-58841 comparison shedding and itch reports combinations with minoxidil scalp itch gone kx shed nipple sensitivity better than ru topical antiandrogen pyrilutamide (kx-826) is a topical androgen-receptor blocker studied for hair loss. hair reports range from regrowth after shedding to no visible change; continued minoxidil and uncertain products complicate comparisons. pyrilutamide is a topical androgen-receptor blocker studied for pattern hair loss. an older 5-month account reported rapid itch relief and less shedding; other accounts report no visible improvement or unwanted symptoms. the company phase 3 announcement reports about ~10 additional hairs/cm\u00b2 over vehicle. community reports also include libido and nipple symptoms, without a reliable frequency estimate. skin, hair & tissue remodeling non-peptide local topical androgen-receptor blocker aimed at the follicle. local site pin topical", "legal_class": null }, { "id": 230, "slug": "finasteride", "name": "Finasteride", "aliases": [ "Propecia", "Proscar", "fin 1mg", "fin", "type-2 5-AR inhibitor", "topical finasteride", "finasteride 0.25%", "Hims / Keeps fin", "compounded topical fin", "PFS" ], "type": "Non-peptide", "category": "Skin, hair & tissue remodeling", "goals_use_cases": [ "skin/hair", "androgenetic alopecia / DHT blockade", "BPH / urinary (labeled 5 mg)", "shedding and hair maintenance", "dutasteride comparison", "topical vs oral 5-AR talk" ], "delivery_methods": [ "oral", "topical" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "finasteride", "propecia", "proscar", "finasterid", "finasteride 1mg", "topical fin", "fin sides", "pfs", "second shed", "topical fin sides", "hair shed", "watery semen", "libido crash", "dht", "hairline", "every other day fin" ], "feel_search": [ "hair shed", "pfs", "watery semen", "libido crash", "propecia", "dht", "hairline", "every other day fin", "second shed", "topical fin sides", "watery semen", "pfs" ], "summary": "Finasteride inhibits type-2 5-alpha-reductase to lower DHT; tablets are used for male-pattern hair loss and prostate enlargement.", "search_blob": "finasteride finasteride propecia proscar fin 1mg fin type-2 5-ar inhibitor topical finasteride finasteride 0.25% hims / keeps fin compounded topical fin pfs finasteride propecia proscar finasterid finasteride 1mg topical fin fin sides pfs second shed topical fin sides hair shed watery semen libido crash dht hairline every other day fin skin/hair androgenetic alopecia / dht blockade bph / urinary (labeled 5 mg) shedding and hair maintenance dutasteride comparison topical vs oral 5-ar talk hair shed pfs watery semen libido crash propecia dht hairline every other day fin second shed topical fin sides watery semen pfs finasteride inhibits type-2 5-alpha-reductase to lower dht; tablets are used for male-pattern hair loss and prostate enlargement. a 4.5-year user describes gradual stabilization over months and ongoing shedding waves despite maintained density. they report no sexual symptoms but mild breast enlargement. finasteride reduces dht formation. hair-loss reports include maintained density, delayed regrowth and no improvement, with differing sexual and mood experiences. shedding is not a guarantee of later regrowth. dutasteride is a different drug, and topical finasteride can still have systemic effects. skin, hair & tissue remodeling non-peptide systemic oral finasteride acts systemically; topical application does not guarantee scalp-only exposure. systemic whole-body circulating", "legal_class": null }, { "id": 231, "slug": "seltorexant", "name": "Seltorexant", "aliases": [ "JNJ-42847922", "MIN-202", "2-SORA", "selective OX2 antagonist", "seltorexant 20 mg" ], "type": "Non-peptide", "category": "Sleep / mood", "goals_use_cases": [ "sleep", "sleep onset / staying asleep", "depression-with-insomnia trial talk", "DSIP comparison", "orexin / DORA comparison", "wearable sleep-score n=1s" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "seltorexant", "seltorexent", "jnj-42847922", "min-202", "ox2 antagonist", "seltorexant 5mg", "seltorexant 20mg", "kimera seltorexant", "dayvigo vs seltorexant", "oura seltorexant", "2-sora", "wired but tired", "micro awakenings", "sleep efficiency", "groggy", "orexin", "better than dsip", "lights out", "kimera", "oura", "whoop", "dayvigo" ], "feel_search": [ "wired but tired", "micro awakenings", "sleep efficiency", "groggy", "orexin", "better than dsip", "lights out", "kimera", "oura", "whoop", "dayvigo", "2-sora" ], "summary": "Seltorexant (JNJ-42847922/MIN-202) is an investigational oral orexin-2 receptor blocker studied for sleep-related problems.", "search_blob": "seltorexant seltorexant jnj-42847922 min-202 2-sora selective ox2 antagonist seltorexant 20 mg seltorexant seltorexent jnj-42847922 min-202 ox2 antagonist seltorexant 5mg seltorexant 20mg kimera seltorexant dayvigo vs seltorexant oura seltorexant 2-sora wired but tired micro awakenings sleep efficiency groggy orexin better than dsip lights out kimera oura whoop dayvigo sleep sleep onset / staying asleep depression-with-insomnia trial talk dsip comparison orexin / dora comparison wearable sleep-score n=1s wired but tired micro awakenings sleep efficiency groggy orexin better than dsip lights out kimera oura whoop dayvigo 2-sora seltorexant (jnj-42847922/min-202) is an investigational oral orexin-2 receptor blocker studied for sleep-related problems. some users describe easier sleep onset, while others say it does little for restless sleep or early awakening. seltorexant is an oral compound people look up for sleep. actual forum reports range from strong sleep-onset benefit to little effect or weak sleep maintenance. not dsip. not ambien. short half-life. still not an approved insomnia pill in these threads. sleep / mood non-peptide systemic systemic oral selective ox2 (orexin-2) blocker. systemic whole-body circulating", "legal_class": null }, { "id": 232, "slug": "tudca", "name": "TUDCA", "aliases": [ "tauroursodeoxycholic acid", "tauroursodeoxycholate", "TUDCA 500", "bile acid supplement", "UDCA taurine conjugate" ], "type": "Non-peptide", "category": "Gut health & recovery", "goals_use_cases": [ "gut health", "liver-enzyme discussions", "bile flow / digestion", "digestion after gallbladder removal", "cell-stress mechanisms (research)", "SIBO / bloating reports", "combinations with NAC" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "tudca", "tudka", "tauroursodeoxycholic", "tudca 500", "tudca 1000", "bile acid", "liver support", "udca", "ursodiol", "gallstones", "glp liver", "liver enzymes / \u201con-cycle\u201d liver talk", "bile flow / fatty-meal digestion", "gallbladder-out digestion", "ER-stress / mitochondria halo", "SIBO / bloating experiments", "NAC stack companion", "bile diarrhea", "right upper pain", "liver enzymes", "on cycle liver", "bloating after fats", "gallbladder", "ox bile", "bile stasis" ], "feel_search": [ "bile diarrhea", "right upper pain", "liver enzymes", "on cycle liver", "bloating after fats", "gallbladder", "ox bile", "gallstones", "glp liver", "bile stasis" ], "summary": "TUDCA is tauroursodeoxycholic acid, an orally supplemented bile acid discussed for liver and digestive concerns.", "search_blob": "tudca tudca tauroursodeoxycholic acid tauroursodeoxycholate tudca 500 bile acid supplement udca taurine conjugate tudca tudka tauroursodeoxycholic tudca 500 tudca 1000 bile acid liver support udca ursodiol gallstones glp liver liver enzymes / \u201con-cycle\u201d liver talk bile flow / fatty-meal digestion gallbladder-out digestion er-stress / mitochondria halo sibo / bloating experiments nac stack companion bile diarrhea right upper pain liver enzymes on cycle liver bloating after fats gallbladder ox bile bile stasis gut health liver-enzyme discussions bile flow / digestion digestion after gallbladder removal cell-stress mechanisms (research) sibo / bloating reports combinations with nac bile diarrhea right upper pain liver enzymes on cycle liver bloating after fats gallbladder ox bile gallstones glp liver bile stasis tudca is tauroursodeoxycholic acid, an orally supplemented bile acid discussed for liver and digestive concerns. accounts include easier digestion or less gallbladder pain, alongside frequent bowel movements, disturbed sleep and other adverse experiences. tudca is an oral bile acid discussed for liver markers and digestion. reports include easier digestion, no tangible change, insomnia, low-blood-sugar episodes and severe reflux; these accounts do not establish liver protection. tudca differs from nac, ox bile and prescribed udca. diarrhea is an adverse experience, not evidence of detoxification or a confirmed diagnosis of excess bile. gut health & recovery non-peptide systemic systemic oral bile acid (taurine-conjugated udca). systemic whole-body circulating", "legal_class": null }, { "id": 233, "slug": "ptd-dbm", "name": "PTD-DBM", "aliases": [ "PTD DBM", "Wnt hair peptide", "PTD-DBM peptide", "protein transduction domain\u2013Dishevelled binding motif", "CXXC5-Dvl disrupting peptide" ], "type": "Peptide", "category": "Skin, hair & tissue remodeling", "goals_use_cases": [ "skin/hair", "androgenetic alopecia / Wnt activation", "microneedling add-on", "minoxidil stack", "wound-adjacent follicle neogenesis talk" ], "delivery_methods": [ "topical" ], "discussion_popularity": "Emerging", "reach": "Local", "misspellings_search_terms": [ "ptd-dbm", "ptd dbm", "ptddbm", "cxxc5 peptide", "wnt hair peptide", "ptd-dmb", "wnt", "cxxc5", "hair peptide", "scalp spray", "not minoxidil", "follicle" ], "feel_search": [ "wnt", "cxxc5", "hair peptide", "scalp spray", "not minoxidil", "follicle" ], "summary": "PTD-DBM is an experimental cell-penetrating peptide designed to interrupt CXXC5\u2013Dishevelled binding in hair-follicle research.", "search_blob": "ptd-dbm ptd-dbm ptd dbm wnt hair peptide ptd-dbm peptide protein transduction domain\u2013dishevelled binding motif cxxc5-dvl disrupting peptide ptd-dbm ptd dbm ptddbm cxxc5 peptide wnt hair peptide ptd-dmb wnt cxxc5 hair peptide scalp spray not minoxidil follicle skin/hair androgenetic alopecia / wnt activation microneedling add-on minoxidil stack wound-adjacent follicle neogenesis talk wnt cxxc5 hair peptide scalp spray not minoxidil follicle ptd-dbm is an experimental cell-penetrating peptide designed to interrupt cxxc5\u2013dishevelled binding in hair-follicle research. one serum user reported less shedding but stopped because of cost; amount and formulation were not supplied. ptd-dbm is an experimental peptide intended to interrupt cxxc5\u2013dishevelled binding in hair-follicle research. human accounts describe topical products with mixed results. reports include less shedding, claimed tiny hairs and no noticeable growth. concurrent hair treatments and uncertain products limit attribution. skin, hair & tissue remodeling peptide local discussed mainly as a scalp preparation; an injection account and oral-product questions involve different, unverified exposures. local site pin topical", "legal_class": null }, { "id": 234, "slug": "nattokinase", "name": "Nattokinase", "aliases": [ "NSK-SD", "NK", "nattokinase 2000 FU", "nattokinase 10800", "fermented soybean enzyme", "natto extract" ], "type": "Non-peptide", "category": "Longevity & cellular energy", "goals_use_cases": [ "longevity", "circulation / \u201cblood flow\u201d talk", "plaque / CIMT hype", "blood pressure experiments", "long-COVID stack", "varicose / \u201csticky blood\u201d lore" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "nattokinase", "nattokinaze", "nato kinase", "nsk-sd", "nattokinase 2000", "nattokinase 12000", "fibrinolytic units", "easy bruising", "nosebleed", "plaque", "sticky blood", "fibrinolytic", "low blood pressure", "natto" ], "feel_search": [ "easy bruising", "nosebleed", "plaque", "sticky blood", "fibrinolytic", "low blood pressure", "natto" ], "summary": "Nattokinase is an enzyme from fermented soy, sold for circulation and discussed in long-COVID groups; activity is measured in fibrinolytic units.", "search_blob": "nattokinase nattokinase nsk-sd nk nattokinase 2000 fu nattokinase 10800 fermented soybean enzyme natto extract nattokinase nattokinaze nato kinase nsk-sd nattokinase 2000 nattokinase 12000 fibrinolytic units easy bruising nosebleed plaque sticky blood fibrinolytic low blood pressure natto longevity circulation / \u201cblood flow\u201d talk plaque / cimt hype blood pressure experiments long-covid stack varicose / \u201csticky blood\u201d lore easy bruising nosebleed plaque sticky blood fibrinolytic low blood pressure natto nattokinase is an enzyme from fermented soy, sold for circulation and discussed in long-covid groups; activity is measured in fibrinolytic units. some long-covid users report less fatigue or easier daily activity; others feel little. a perceived symptom change does not show that clots or plaque have been removed. nattokinase is an oral enzyme supplement discussed for circulation and long-covid symptoms. reports include easier activity, no benefit, light-headedness or worsening; they do not establish clot removal. not a peptide. not a statin. the 36% plaque number is a contested chart review. longevity & cellular energy non-peptide systemic oral enzyme supplement discussed for circulatory effects; intact active-enzyme kinetics remain unresolved. systemic whole-body circulating", "legal_class": null }, { "id": 235, "slug": "ru-58841", "name": "RU-58841", "aliases": [ "RU58841", "PSK-3841", "PSK3841", "RU 58841", "topical RU", "5% RU" ], "type": "Non-peptide", "category": "Skin, hair & tissue remodeling", "goals_use_cases": [ "skin/hair", "androgenetic alopecia / topical androgen-receptor research", "comparisons with finasteride", "pyrilutamide comparison", "topical-formulation differences" ], "delivery_methods": [ "topical" ], "discussion_popularity": "Medium", "reach": "Local", "misspellings_search_terms": [ "ru-58841", "ru58841", "ru 58841", "psk-3841", "psk3841", "ru 5%", "topical ru", "ru58841 mix", "ru heart", "ru identity", "skin/hair", "androgenetic alopecia / local androgen-receptor block", "finasteride-avoid topical add-on", "pyrilutamide comparison", "DIY ethanol/PG mix", "scalp sting", "went systemic", "heart scare", "5% ru", "ethanol pg mix", "nuclear stack", "vs kx-826" ], "feel_search": [ "scalp sting", "went systemic", "heart scare", "5% ru", "ethanol pg mix", "nuclear stack", "vs kx-826", "ru heart", "ru identity", "went systemic" ], "summary": "RU-58841 is an experimental nonsteroidal androgen-receptor blocker discussed as a topical hair-loss product.", "search_blob": "ru-58841 ru-58841 ru58841 psk-3841 psk3841 ru 58841 topical ru 5% ru ru-58841 ru58841 ru 58841 psk-3841 psk3841 ru 5% topical ru ru58841 mix ru heart ru identity skin/hair androgenetic alopecia / local androgen-receptor block finasteride-avoid topical add-on pyrilutamide comparison diy ethanol/pg mix scalp sting went systemic heart scare 5% ru ethanol pg mix nuclear stack vs kx-826 skin/hair androgenetic alopecia / topical androgen-receptor research comparisons with finasteride pyrilutamide comparison topical-formulation differences scalp sting went systemic heart scare 5% ru ethanol pg mix nuclear stack vs kx-826 ru heart ru identity went systemic ru-58841 is an experimental nonsteroidal androgen-receptor blocker discussed as a topical hair-loss product. the inspected thread includes palpitations and a perceived facial change after use, with the author reporting different degrees of recovery. ru-58841 is an experimental topical androgen-receptor blocker discussed for hair loss. some report less shedding without a 5-ar inhibitor; others report no benefit or symptoms prompting cessation. reports include regrowth, no improvement and chest, mood or sexual symptoms. their frequency is unknown; scalp application does not exclude systemic exposure. skin, hair & tissue remodeling non-peptide local topical scalp application; the intended local target does not exclude systemic exposure. local site pin topical", "legal_class": null }, { "id": 236, "slug": "clascoterone", "name": "Clascoterone", "aliases": [ "Winlevi", "Breezula", "CB-03-01", "cortexolone 17\u03b1-propionate", "clascoterone 1%", "clascoterone 5%" ], "type": "Non-peptide", "category": "Skin, hair & tissue remodeling", "goals_use_cases": [ "skin/hair", "acne (labeled 1% cream)", "androgenetic alopecia / Breezula-class 5%", "topical AR block without swallowing 5-AR", "Winlevi vs RU vs pyrilutamide" ], "delivery_methods": [ "topical" ], "discussion_popularity": "Medium", "reach": "Local", "misspellings_search_terms": [ "clascoterone", "clasoterone", "winlevi", "breezula", "cb-03-01", "cb0301", "clascoterone 5%", "winlevi hair", "1% vs 5%", "scalp cream", "topical anti-androgen", "acne cream on hairline", "hpa axis" ], "feel_search": [ "winlevi hair", "breezula", "1% vs 5%", "scalp cream", "topical anti-androgen", "acne cream on hairline", "hpa axis" ], "summary": "Clascoterone is a topical androgen-receptor blocker: Winlevi is an acne cream, while higher-strength scalp formulations are studied for hair loss.", "search_blob": "clascoterone clascoterone winlevi breezula cb-03-01 cortexolone 17\u03b1-propionate clascoterone 1% clascoterone 5% clascoterone clasoterone winlevi breezula cb-03-01 cb0301 clascoterone 5% winlevi hair 1% vs 5% scalp cream topical anti-androgen acne cream on hairline hpa axis skin/hair acne (labeled 1% cream) androgenetic alopecia / breezula-class 5% topical ar block without swallowing 5-ar winlevi vs ru vs pyrilutamide winlevi hair breezula 1% vs 5% scalp cream topical anti-androgen acne cream on hairline hpa axis clascoterone is a topical androgen-receptor blocker: winlevi is an acne cream, while higher-strength scalp formulations are studied for hair loss. a user of a nonstandard concentrated scalp solution reports less shedding but disrupted sleep and low energy. they did not measure adrenal suppression. clascoterone blocks androgen receptors in skin. the 1% acne cream and higher-strength scalp solutions differ in formulation, evidence and reported outcomes. a fivefold concentration difference is not a fivefold dose or effectiveness difference. topical use does not guarantee skin-only effects. skin, hair & tissue remodeling non-peptide local topical androgen-receptor antagonist. local site pin topical", "legal_class": null }, { "id": 237, "slug": "j-147", "name": "J-147", "aliases": [ "J147", "J 147", "CAD-031 related curcumin analog talk", "Salk J147", "BioMind J-147" ], "type": "Non-peptide", "category": "Cognitive research compounds", "goals_use_cases": [ "cognition", "memory / \u201cAlzheimer\u2019s mouse drug\u201d halo", "mitochondrial / ATP synthase talk", "Dihexa stack (BioMind-class)", "longevity nootropic" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "j-147", "j147", "j 147", "jay 147", "salk j147", "biomind j147", "curcumin analog j147", "mouse alzheimer", "mitochondria", "biomind", "with dihexa", "nothing burger", "curcumin analog", "brain fog" ], "feel_search": [ "mouse alzheimer", "mitochondria", "biomind", "with dihexa", "nothing burger", "curcumin analog", "brain fog" ], "summary": "J-147 is an experimental curcumin-derived small molecule studied for Alzheimer\u2019s-related biology, with biohacker interest in cognition, mood and energy.", "search_blob": "j-147 j-147 j147 j 147 cad-031 related curcumin analog talk salk j147 biomind j-147 j-147 j147 j 147 jay 147 salk j147 biomind j147 curcumin analog j147 mouse alzheimer mitochondria biomind with dihexa nothing burger curcumin analog brain fog cognition memory / \u201calzheimer\u2019s mouse drug\u201d halo mitochondrial / atp synthase talk dihexa stack (biomind-class) longevity nootropic mouse alzheimer mitochondria biomind with dihexa nothing burger curcumin analog brain fog j-147 is an experimental curcumin-derived small molecule studied for alzheimer\u2019s-related biology, with biohacker interest in cognition, mood and energy. reports range from better mood or energy to sleepiness, fatigue, disrupted sleep or little change. some effects appear after days, but the sparse accounts do not establish a typical course. j-147 is an experimental small molecule discussed for memory, mood and brain aging. human reports include subtle benefit, little change, fatigue and disrupted sleep; animal findings do not establish human efficacy. vendor 10\u201320 mg/day claims and individual oral reports are separate from animal research and do not establish a validated human amount. cognitive research compounds non-peptide systemic systemic oral experimental small molecule (curcumin-derived neurotrophic). systemic whole-body circulating", "legal_class": null }, { "id": 238, "slug": "pea", "name": "PEA", "aliases": [ "palmitoylethanolamide", "Levagen+", "palmitoyl ethanolamide", "PeaPure", "micronized PEA", "ultra-micronized PEA", "um-PEA" ], "type": "Non-peptide", "category": "Immune & inflammation adjacents", "goals_use_cases": [ "recovery", "pain / \u201cnatural endocannabinoid\u201d talk", "inflammation / mast-cell lore", "sleep when pain is the problem", "nerve pain experiments", "not phenylethylamine" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "pea", "palmitoylethanolamide", "palmitoyl ethanolamide", "levagen", "peapure", "micronized pea", "um-pea", "not phenylethylamine", "background ache", "mast cell", "slow pain relief", "inflammation", "nerve pain" ], "feel_search": [ "background ache", "mast cell", "not phenylethylamine", "slow pain relief", "levagen", "inflammation", "nerve pain" ], "summary": "PEA here is palmitoylethanolamide, an oral fat-derived signaling molecule discussed for pain and inflammation. Reports include less pain, uncertain or absent benefit, fading\u2026", "search_blob": "pea pea palmitoylethanolamide levagen+ palmitoyl ethanolamide peapure micronized pea ultra-micronized pea um-pea pea palmitoylethanolamide palmitoyl ethanolamide levagen peapure micronized pea um-pea not phenylethylamine background ache mast cell slow pain relief inflammation nerve pain recovery pain / \u201cnatural endocannabinoid\u201d talk inflammation / mast-cell lore sleep when pain is the problem nerve pain experiments not phenylethylamine background ache mast cell not phenylethylamine slow pain relief levagen inflammation nerve pain pea here is palmitoylethanolamide, an oral fat-derived signaling molecule discussed for pain and inflammation. reports include less pain, uncertain or absent benefit, fading\u2026 one person reported more manageable pelvic/back pain after about a week, with later relief also involving physical therapy. other accounts describe no useful change, fading benefit or adverse symptoms. pea here is palmitoylethanolamide, an oral fat-derived signaling molecule discussed for pain and inflammation. reports include less pain, uncertain or absent benefit, fading improvement and adverse symptoms. people discuss weeks-long trials and occasional earlier relief; micronized, ultra-micronized and levagen+ products are not interchangeable. immune & inflammation adjacents non-peptide systemic systemic oral fatty-acid amide (endocannabinoid-like, ppar-\u03b1). systemic whole-body circulating", "legal_class": null }, { "id": 239, "slug": "telmisartan", "name": "Telmisartan", "aliases": [ "Micardis", "telmi", "ARB", "telmisartan 20", "telmisartan 40", "telmisartan 80" ], "type": "Non-peptide", "category": "Longevity & cellular energy", "goals_use_cases": [ "longevity", "blood pressure / endothelial talk", "longevity interest in an angiotensin-receptor blocker", "PPAR-gamma and metabolic discussion", "TRT + tadalafil BP stack", "losartan comparison" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "telmisartan", "telmisartin", "micardis", "telmi", "telmisartan 20", "telmisartan 40", "arb longevity", "dizzy on standing", "blood pressure", "ppar", "vs losartan", "with tadalafil", "longevity arb", "lightheaded gym" ], "feel_search": [ "dizzy on standing", "blood pressure", "ppar", "vs losartan", "with tadalafil", "longevity arb", "lightheaded gym" ], "summary": "Telmisartan is an oral angiotensin-receptor blocker (ARB), sold as Micardis and generics for blood-pressure treatment.", "search_blob": "telmisartan telmisartan micardis telmi arb telmisartan 20 telmisartan 40 telmisartan 80 telmisartan telmisartin micardis telmi telmisartan 20 telmisartan 40 arb longevity dizzy on standing blood pressure ppar vs losartan with tadalafil longevity arb lightheaded gym longevity blood pressure / endothelial talk longevity interest in an angiotensin-receptor blocker ppar-gamma and metabolic discussion trt + tadalafil bp stack losartan comparison dizzy on standing blood pressure ppar vs losartan with tadalafil longevity arb lightheaded gym telmisartan is an oral angiotensin-receptor blocker (arb), sold as micardis and generics for blood-pressure treatment. people report different responses to combinations with tadalafil: lower blood pressure in one account and hypotensive episodes in another. telmisartan is an oral angiotensin-receptor blocker for blood-pressure treatment. metabolic and longevity interest does not establish benefit for people whose pressure is already normal. reports include lower readings, no improvement and fatigue or dizziness, often with tadalafil or other active drugs. longevity & cellular energy non-peptide systemic systemic oral angiotensin-ii receptor blocker (arb). systemic whole-body circulating", "legal_class": null }, { "id": 241, "slug": "pdrn", "name": "PDRN", "aliases": [ "polydeoxyribonucleotide", "salmon DNA", "PDRN mesotherapy" ], "type": "Non-peptide", "category": "Skin, hair & tissue remodeling", "goals_use_cases": [ "skin/hair", "K-beauty \u201csalmon DNA\u201d facial", "under-eye / texture / glow", "scalp mesotherapy", "post-laser recovery talk" ], "delivery_methods": [ "intradermal" ], "discussion_popularity": "Medium", "reach": "Local", "misspellings_search_terms": [ "pdrn", "rejuran", "rejuran healer", "salmon dna", "polydeoxyribonucleotide", "polynucleotide", "pdrn hair", "salmon sperm facial", "Rejuran", "Rejuran Healer", "polynucleotide PN", "papules", "pillow face", "under eye", "scalp meso", "bruise grid", "pn vs pdrn", "not filler", "c-pdrn serum" ], "feel_search": [ "papules", "salmon dna", "pillow face", "under eye", "rejuran", "scalp meso", "bruise grid", "pn vs pdrn", "not filler", "c-pdrn serum" ], "summary": "PDRN is a DNA-fragment material discussed for skin repair. It differs from the longer polynucleotide material used in Rejuran injections.", "search_blob": "pdrn pdrn polydeoxyribonucleotide salmon dna pdrn mesotherapy pdrn rejuran rejuran healer salmon dna polydeoxyribonucleotide polynucleotide pdrn hair salmon sperm facial rejuran rejuran healer polynucleotide pn papules pillow face under eye scalp meso bruise grid pn vs pdrn not filler c-pdrn serum skin/hair k-beauty \u201csalmon dna\u201d facial under-eye / texture / glow scalp mesotherapy post-laser recovery talk papules salmon dna pillow face under eye rejuran scalp meso bruise grid pn vs pdrn not filler c-pdrn serum pdrn is a dna-fragment material discussed for skin repair. it differs from the longer polynucleotide material used in rejuran injections. one treatment account described calmer redness and better hydration, but less lasting tightening than rejuran; other procedures were also involved. pdrn is a dna-fragment material discussed for skin repair. reports mix distinct pdrn, pn and cosmetic products and include smoother texture, painful treatment, irritation or little lasting change. not a peptide. cosmetic skin-booster goals differ from volume filling; hair mesotherapy is additional, thinner-evidence discussion. skin, hair & tissue remodeling non-peptide local skin and scalp cosmetic discussion; topical products, pn injections and pharmaceutical pdrn have separate routes and evidence. local site pin topical", "legal_class": null }, { "id": 242, "slug": "agmatine", "name": "Agmatine", "aliases": [ "agmatine sulfate", "decarboxylated arginine", "AGM", "agmatine 1g", "GDA agmatine talk" ], "type": "Non-peptide", "category": "Cognitive research compounds", "goals_use_cases": [ "cognition", "performance", "gym pump / nitric-oxide adjacent", "nerve pain experiments", "stimulant-tolerance lore", "mood / NMDA talk" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "agmatine", "agmantine", "agmatine sulfate", "agmatin", "agmatine 500", "agmatine 1g", "decarboxylated arginine", "pump", "blunts stims", "flat mood", "nerve pain", "empty stomach", "not citrulline" ], "feel_search": [ "pump", "blunts stims", "flat mood", "nerve pain", "empty stomach", "not citrulline", "agmatine sulfate" ], "summary": "Agmatine is an arginine-derived compound sold as agmatine sulfate, discussed for anxiety, nerve pain and workout pumps.", "search_blob": "agmatine agmatine agmatine sulfate decarboxylated arginine agm agmatine 1g gda agmatine talk agmatine agmantine agmatine sulfate agmatin agmatine 500 agmatine 1g decarboxylated arginine pump blunts stims flat mood nerve pain empty stomach not citrulline cognition performance gym pump / nitric-oxide adjacent nerve pain experiments stimulant-tolerance lore mood / nmda talk pump blunts stims flat mood nerve pain empty stomach not citrulline agmatine sulfate agmatine is an arginine-derived compound sold as agmatine sulfate, discussed for anxiety, nerve pain and workout pumps. one anxiety account describes several hours of calm followed by returning anxiety; another says the effect is patchy. that does not establish a universal duration. agmatine is an oral arginine-derived compound discussed for workout pumps, anxiety, mood and nerve pain. reports include calm or renewed enjoyment, no benefit, and unwanted fog or emotional flattening. a weaker stimulant effect does not establish a tolerance reset. other accounts include stomach symptoms, palpitations or mental changes after stopping. cognitive research compounds non-peptide systemic systemic oral arginine metabolite (not a peptide). systemic whole-body circulating", "legal_class": null }, { "id": 243, "slug": "pentosan-pps", "name": "Pentosan PPS", "aliases": [ "pentosan polysulfate", "Elmiron", "pentosan polysulfate sodium", "PPS", "iPPS", "Adequan-adjacent pentosan talk" ], "type": "Non-peptide", "category": "Healing & repair", "goals_use_cases": [ "recovery", "interstitial cystitis (labeled oral)", "joint / cartilage regenerative-clinic talk", "proposed bladder GAG-layer protection", "maculopathy watch-for" ], "delivery_methods": [ "oral", "subcutaneous" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "pentosan", "pentosan pps", "pentosan polysulfate", "elmiron", "elmeron", "ipps", "pps injection", "pentosan maculopathy", "maculopathy", "night vision", "bladder pain", "knee injection", "not bpc", "reading trouble" ], "feel_search": [ "maculopathy", "night vision", "bladder pain", "knee injection", "elmiron", "not bpc", "reading trouble" ], "summary": "Pentosan polysulfate sodium is a modified carbohydrate, not a peptide. Oral bladder-pain treatment and joint injections involve different products and exposures.", "search_blob": "pentosan pps pentosan-pps pentosan polysulfate elmiron pentosan polysulfate sodium pps ipps adequan-adjacent pentosan talk pentosan pentosan pps pentosan polysulfate elmiron elmeron ipps pps injection pentosan maculopathy maculopathy night vision bladder pain knee injection not bpc reading trouble recovery interstitial cystitis (labeled oral) joint / cartilage regenerative-clinic talk proposed bladder gag-layer protection maculopathy watch-for maculopathy night vision bladder pain knee injection elmiron not bpc reading trouble pentosan polysulfate sodium is a modified carbohydrate, not a peptide. oral bladder-pain treatment and joint injections involve different products and exposures. oral bladder-pain reports describe slow, variable relief; one long-term user noticed less urgency and pain, while another was still waiting near six months. pentosan polysulfate sodium is a modified carbohydrate, not a peptide. oral bladder-pain treatment and joint injections involve different products and exposures. reports range from relief to no useful change. retinal damage can persist or progress after stopping, and injections do not remove that concern. healing & repair non-peptide systemic systemic heparinoid polysaccharide. systemic whole-body circulating", "legal_class": null }, { "id": 244, "slug": "berberine", "name": "Berberine", "aliases": [ "berberine HCl", "berberine 500", "Oregon grape alkaloid talk" ], "type": "Non-peptide", "category": "Metabolic & longevity adjacents", "goals_use_cases": [ "fat loss", "fat loss / glucose talk", "metformin comparison", "lipids / \u201cpoor man\u2019s GLP\u201d lore", "PCOS-adjacent community", "AMPK" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "berberine", "berberine hcl", "berberin", "dihydroberberine", "glucovantage", "berberine 500", "natural metformin", "hypoglycemia", "glucose crash", "GlucoVantage", "\u201cnatural metformin\u201d", "diarrhea", "cgm", "yellow stool", "ampk", "with meals", "stack with metformin" ], "feel_search": [ "diarrhea", "natural metformin", "cgm", "yellow stool", "ampk", "dihydroberberine", "with meals", "glucose crash", "hypoglycemia", "stack with metformin" ], "summary": "Berberine is a plant alkaloid sold as an oral supplement for glucose and lipid control, with frequent weight-loss discussion.", "search_blob": "berberine berberine berberine hcl berberine 500 oregon grape alkaloid talk berberine berberine hcl berberin dihydroberberine glucovantage berberine 500 natural metformin hypoglycemia glucose crash glucovantage \u201cnatural metformin\u201d diarrhea cgm yellow stool ampk with meals stack with metformin fat loss fat loss / glucose talk metformin comparison lipids / \u201cpoor man\u2019s glp\u201d lore pcos-adjacent community ampk diarrhea natural metformin cgm yellow stool ampk dihydroberberine with meals glucose crash hypoglycemia stack with metformin berberine is a plant alkaloid sold as an oral supplement for glucose and lipid control, with frequent weight-loss discussion. some users describe loose stools or stomach discomfort; others report none. weight-loss accounts in this thread include calorie restriction, exercise or combination products. berberine is an oral plant-derived supplement discussed for glucose, cholesterol and appetite. reports include quieter cravings, increased hunger, no benefit and gut symptoms, often with other changes. hcl, dhb and phytosome products are distinct. greater absorption does not establish better results or fewer gut effects. metabolic & longevity adjacents non-peptide systemic systemic oral plant alkaloid (berberine hcl). systemic whole-body circulating", "legal_class": null }, { "id": 245, "slug": "choline", "name": "Choline", "aliases": [ "Alpha-GPC", "citicoline", "CDP-choline", "choline bitartrate", "alpha GPC", "phosphatidylcholine", "Cognizin" ], "type": "Non-peptide", "category": "Cognitive research compounds", "goals_use_cases": [ "cognition", "racetam-related headache discussion", "focus / memory combinations", "exercise-performance research (Alpha-GPC)", "food versus supplement sources" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "choline", "alpha gpc", "alphagpc", "cdp choline", "citicoline", "choline bitartrate", "cognizin", "choline dump", "50% gpc", "cognition", "racetam \u201ccholine dump\u201d prevention", "focus / memory stack", "gym power (Alpha-GPC 600 mg talk)", "eggs vs a capsule", "racetam headache", "fishy sweat", "tmao", "focus", "bitartrate fishy" ], "feel_search": [ "racetam headache", "fishy sweat", "alpha gpc", "choline dump", "tmao", "focus", "citicoline", "cognizin", "50% gpc", "bitartrate fishy" ], "summary": "Choline is an essential nutrient; supplements such as alpha-GPC, citicoline and phosphatidylcholine supply it in different forms.", "search_blob": "choline choline alpha-gpc citicoline cdp-choline choline bitartrate alpha gpc phosphatidylcholine cognizin choline alpha gpc alphagpc cdp choline citicoline choline bitartrate cognizin choline dump 50% gpc cognition racetam \u201ccholine dump\u201d prevention focus / memory stack gym power (alpha-gpc 600 mg talk) eggs vs a capsule racetam headache fishy sweat tmao focus bitartrate fishy cognition racetam-related headache discussion focus / memory combinations exercise-performance research (alpha-gpc) food versus supplement sources racetam headache fishy sweat alpha gpc choline dump tmao focus citicoline cognizin 50% gpc bitartrate fishy choline is an essential nutrient; supplements such as alpha-gpc, citicoline and phosphatidylcholine supply it in different forms. one alpha-gpc account describes a headache followed by energy and clearer reading, but later attempts brought tiredness and depressive thoughts and the author stopped. eggs, vyvanse and other supplements complicate attribution. choline is an essential nutrient supplied by food and several supplement forms. reports range from clearer focus to no change, headache or low mood; the forms and their label quantities differ. a racetam-associated headache does not diagnose choline deficiency. adding a supplement can also coincide with headache or other symptoms, and form weights are not equivalent nutrient amounts. cognitive research compounds non-peptide systemic systemic choline \u2014 several oral forms that are not the same milligram. systemic whole-body circulating", "legal_class": null }, { "id": 246, "slug": "atx-304", "name": "ATX-304", "aliases": [ "O-304", "OS-01", "ATX304", "Amplifier Therapeutics ATX-304", "O304", "ATX 304", "Cambrian ATX-304" ], "type": "Non-peptide", "category": "Metabolic & longevity adjacents", "goals_use_cases": [ "fat loss", "metabolic health", "AMPK", "mitochondria", "GLP-1 stack talk", "endurance" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "atx-304", "atx304", "atx 304", "o-304", "o304", "os-01", "os01", "ampk activator", "mots-c replacement", "ampk", "mots-c", "oral", "uncoupling", "glp stack", "metformin pivot", "fatty liver", "4am crash", "rewire", "phase 1b" ], "feel_search": [ "ampk", "mots-c", "oral", "uncoupling", "glp stack", "metformin pivot", "fatty liver", "4am crash", "rewire", "phase 1b" ], "summary": "ATX-304 (O-304) is an investigational oral small molecule studied for metabolic effects and discussed for energy and fat loss.", "search_blob": "atx-304 atx-304 o-304 os-01 atx304 amplifier therapeutics atx-304 o304 atx 304 cambrian atx-304 atx-304 atx304 atx 304 o-304 o304 os-01 os01 ampk activator mots-c replacement ampk mots-c oral uncoupling glp stack metformin pivot fatty liver 4am crash rewire phase 1b fat loss metabolic health ampk mitochondria glp-1 stack talk endurance ampk mots-c oral uncoupling glp stack metformin pivot fatty liver 4am crash rewire phase 1b atx-304 (o-304) is an investigational oral small molecule studied for metabolic effects and discussed for energy and fat loss. one public account reports more sweating during cardio, with additional heat when combined with slu. exercise and co-use prevent an isolated atx effect claim. atx-304, also called o304, is an investigational oral small molecule studied for ampk-related metabolic effects. personal accounts include both improved energy and little benefit. research-product accounts describe heat, poorer recovery and mixed cardio results as well as weight-loss claims. co-use prevents clean attribution. metabolic & longevity adjacents non-peptide systemic systemic oral small molecule. systemic whole-body circulating", "legal_class": null }, { "id": 247, "slug": "pn-477", "name": "PN-477", "aliases": [ "PN477", "PN-477o", "PN-477sc", "Protagonist PN-477", "PN 477", "PTGX triple-G" ], "type": "Peptide", "category": "Metabolic / GLP-1 class", "goals_use_cases": [ "fat loss", "appetite control", "oral GLP talk", "metabolic health", "reta comparison" ], "delivery_methods": [ "oral", "subcutaneous" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "pn-477", "pn477", "pn 477", "pn-477o", "pn-477sc", "protagonist peptide", "ptgx", "reta competitor", "oral triple g", "protagonist", "pn477o", "amylin rumor", "pipeline" ], "feel_search": [ "reta competitor", "oral triple g", "protagonist", "pn477o", "amylin rumor", "pipeline" ], "summary": "PN-477 is an obesity-development candidate targeting GLP-1, GIP and glucagon receptors, with oral and injectable versions.", "search_blob": "pn-477 pn-477 pn477 pn-477o pn-477sc protagonist pn-477 pn 477 ptgx triple-g pn-477 pn477 pn 477 pn-477o pn-477sc protagonist peptide ptgx reta competitor oral triple g protagonist pn477o amylin rumor pipeline fat loss appetite control oral glp talk metabolic health reta comparison reta competitor oral triple g protagonist pn477o amylin rumor pipeline pn-477 is an obesity-development candidate targeting glp-1, gip and glucagon receptors, with oral and injectable versions. the inspected social post discusses a future oral or injected drug; it contains no first-person experience. pn-477 is an experimental obesity peptide targeting glp-1, gip and glucagon receptors. the inspected discussions report expectations rather than personal results. the sponsor describes three targets. the extra amylin claim in unlinked social commentary is unsubstantiated. metabolic / glp-1 class peptide systemic systemic multi-agonist peptide. systemic whole-body circulating", "legal_class": null }, { "id": 248, "slug": "tak-653", "name": "TAK-653", "aliases": [ "osavampator", "TAK653", "AMPA PAM TAK-653", "TAK 653" ], "type": "Non-peptide", "category": "Cognitive research compounds", "goals_use_cases": [ "cognition", "focus / working memory", "depression-pipeline talk", "nootropic stacks" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "tak-653", "tak653", "tak 653", "osavampator", "ampa pam", "tak 653 dose", "ampa", "digit span", "working memory", "vivid dreams", "cerebrolysin stack" ], "feel_search": [ "ampa", "digit span", "osavampator", "working memory", "vivid dreams", "cerebrolysin stack" ], "summary": "TAK-653, or osavampator, is an investigational oral AMPA-receptor positive modulator from a depression program, discussed for cognition.", "search_blob": "tak-653 tak-653 osavampator tak653 ampa pam tak-653 tak 653 tak-653 tak653 tak 653 osavampator ampa pam tak 653 dose ampa digit span working memory vivid dreams cerebrolysin stack cognition focus / working memory depression-pipeline talk nootropic stacks ampa digit span osavampator working memory vivid dreams cerebrolysin stack tak-653, or osavampator, is an investigational oral ampa-receptor positive modulator from a depression program, discussed for cognition. one user described good retention and focus with head pressure, mistakes, irritability and vivid dreams, then reported pressure resolving after lowering the amount. other accounts describe no benefit or emotional blunting; none establishes a universal response. tak-653 is an investigational oral ampa-receptor modulator discussed for cognition and mood. reports include easier recall or articulation, no benefit, poor sleep, irritability and emotional blunting. the recurring 2 mg forum example is not an established default. quieter thinking can coexist with less ambition or worse performance. cognitive research compounds non-peptide systemic systemic oral ampa receptor positive allosteric modulator. systemic whole-body circulating", "legal_class": null }, { "id": 249, "slug": "brp", "name": "BRP", "aliases": [ "BRINP2-related peptide", "BRINP2", "THRILRRLFNLC", "BRINP2 related peptide", "BRINP-2", "Stanford BRP", "natural Ozempic peptide" ], "type": "Peptide", "category": "Metabolic / GLP-1 class", "goals_use_cases": [ "fat loss", "appetite control", "metabolic health", "non-GLP hunger talk", "muscle-sparing cut talk" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "brp", "brinp2", "brinp-2", "brinp2 related peptide", "thrillrrlfnlc", "natural ozempic peptide", "stanford peptide brp", "natural ozempic", "appetite peptide", "no nausea glp", "stanford peptide", "12 amino acid" ], "feel_search": [ "natural ozempic", "brinp2", "appetite peptide", "no nausea glp", "stanford peptide", "12 amino acid" ], "summary": "BRP (BRINP2-related peptide) is a 12-amino-acid research peptide studied for reducing food intake in animals.", "search_blob": "brp brp brinp2-related peptide brinp2 thrilrrlfnlc brinp2 related peptide brinp-2 stanford brp natural ozempic peptide brp brinp2 brinp-2 brinp2 related peptide thrillrrlfnlc natural ozempic peptide stanford peptide brp natural ozempic appetite peptide no nausea glp stanford peptide 12 amino acid fat loss appetite control metabolic health non-glp hunger talk muscle-sparing cut talk natural ozempic brinp2 appetite peptide no nausea glp stanford peptide 12 amino acid brp (brinp2-related peptide) is a 12-amino-acid research peptide studied for reducing food intake in animals. the inspected discussion proposes a future two-week experiment and repeats animal findings. it reports no completed personal experience. brp is a 12-amino-acid research peptide studied for reducing animal food intake through signaling separate from glp-1 receptors. human discussion here consists of expectations and plans. the inspected record has no completed human dose or outcome report. animal amounts and amidation findings do not validate a research vial. metabolic / glp-1 class peptide systemic systemic 12-amino-acid peptide from brinp2. systemic whole-body circulating", "legal_class": null }, { "id": 250, "slug": "mtx-325", "name": "MTX-325", "aliases": [ "MTX325", "MTX115325", "USP30 inhibitor MTX-325", "MTX 325", "MTX-115325", "Mission MTX325" ], "type": "Non-peptide", "category": "Mitochondrial & metabolic compounds", "goals_use_cases": [ "longevity / cellular energy", "mitophagy / mitochondrial recycling", "Parkinson pipeline talk", "\u201cgiga urolithin\u201d talk", "brain mito quality" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "mtx-325", "mtx325", "mtx 325", "mtx115325", "usp30", "mission therapeutics", "giga urolithin", "mitophagy pill", "parkinson oral", "brain mitochondria" ], "feel_search": [ "giga urolithin", "usp30", "mitophagy pill", "parkinson oral", "mission therapeutics", "brain mitochondria" ], "summary": "MTX325 is an experimental oral USP30 inhibitor being studied for Parkinson's disease by promoting removal of damaged mitochondria.", "search_blob": "mtx-325 mtx-325 mtx325 mtx115325 usp30 inhibitor mtx-325 mtx 325 mtx-115325 mission mtx325 mtx-325 mtx325 mtx 325 mtx115325 usp30 mission therapeutics giga urolithin mitophagy pill parkinson oral brain mitochondria longevity / cellular energy mitophagy / mitochondrial recycling parkinson pipeline talk \u201cgiga urolithin\u201d talk brain mito quality giga urolithin usp30 mitophagy pill parkinson oral mission therapeutics brain mitochondria mtx325 is an experimental oral usp30 inhibitor being studied for parkinson's disease by promoting removal of damaged mitochondria. the reviewed sources do not provide a reliable human feel profile. brain penetration and safety testing do not establish better energy, focus or parkinson's symptoms. mtx-325 is an experimental oral usp30 inhibitor being developed for parkinson's disease. the inspected community material supplies no reliable felt-effect timeline. sponsor-reported brain exposure is not clinical benefit. trial capsule strengths are not a community dose history or a urolithin a equivalent. mitochondrial & metabolic compounds non-peptide systemic systemic oral small molecule. systemic whole-body circulating", "legal_class": null }, { "id": 251, "slug": "flgr-242", "name": "FLGR-242", "aliases": [ "FLGR242", "FGLR242", "SlimAssist", "FS I-I", "MicroFLGR", "FLGR 242", "FGLR-242", "Follistatin FLGR242", "BioLongevity FLGR242", "FSI-I", "FS-I/I", "BLL follistatin" ], "type": "Peptide", "category": "Growth factors / muscle", "goals_use_cases": [ "muscle growth", "myostatin inhibition", "GLP muscle-spare talk", "recomp", "vs Follistatin 344" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "flgr-242", "flgr242", "fglr242", "fglr-242", "recombinant follistatin", "biolongevity follistatin", "slimassist", "flgr 242 dose", "fs i-i", "fsi-i", "microflgr", "flgr forever", "flgr dexa", "albumin-bound follistatin", "myostatin", "glp muscle spare", "biolongevity", "19 day half life", "fst-344 vs flgr", "lose muscle when stop", "1.5 lb a week", "alex padron", "slimassist women" ], "feel_search": [ "recombinant follistatin", "myostatin", "glp muscle spare", "biolongevity", "19 day half life", "fst-344 vs flgr", "lose muscle when stop", "1.5 lb a week", "alex padron", "slimassist women" ], "summary": "FLGR-242 is a seller-named injectable modified-follistatin product marketed for muscle growth; its claimed long duration is not established human PK.", "search_blob": "flgr-242 flgr-242 flgr242 fglr242 slimassist fs i-i microflgr flgr 242 fglr-242 follistatin flgr242 biolongevity flgr242 fsi-i fs-i/i bll follistatin flgr-242 flgr242 fglr242 fglr-242 recombinant follistatin biolongevity follistatin slimassist flgr 242 dose fs i-i fsi-i microflgr flgr forever flgr dexa albumin-bound follistatin myostatin glp muscle spare biolongevity 19 day half life fst-344 vs flgr lose muscle when stop 1.5 lb a week alex padron slimassist women muscle growth myostatin inhibition glp muscle-spare talk recomp vs follistatin 344 recombinant follistatin myostatin glp muscle spare biolongevity 19 day half life fst-344 vs flgr lose muscle when stop 1.5 lb a week alex padron slimassist women flgr-242 is a seller-named injectable modified-follistatin product marketed for muscle growth; its claimed long duration is not established human pk. one slimassist user perceived rapid muscle change without verified body-composition measurements. other accounts describe gym progress, no noticeable benefit, or painful local reactions that prompted stopping. flgr-242 is a seller-named injectable modified-follistatin product marketed for muscle growth. promotional 7\u201310 lb lean-gain claims are n=1 accounts; other users report no noticeable benefit or painful local reactions. seller claims describe intervals of 1\u20132 weeks, distinct from 100 mcg daily fs-344 charts. neither schedule establishes flgr kinetics, safe use or lasting gains. growth factors / muscle peptide systemic purported systemic modified-follistatin construct; the seller's design claims are not independently verified. systemic whole-body circulating", "legal_class": null }, { "id": 253, "slug": "lithium-orotate", "name": "Lithium orotate", "aliases": [ "OTC lithium", "low-dose lithium", "Li-orotate", "lithium orotate 5 mg", "elemental lithium supplement" ], "type": "Non-peptide", "category": "Cognitive research compounds", "goals_use_cases": [ "mood", "longevity / Alzheimer\u2019s talk", "microdose lithium", "vs psychiatric lithium carbonate" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "lithium orotate", "lithium oratate", "li orotate", "otc lithium", "5 mg lithium", "yankner lithium", "orotate", "microdose lithium", "yankner", "mood mineral", "alzheimers lithium" ], "feel_search": [ "orotate", "microdose lithium", "yankner", "mood mineral", "5 mg lithium", "alzheimers lithium" ], "summary": "Lithium orotate is a lithium salt sold as an oral supplement for mood-related purposes; elemental lithium and total salt weight are different label numbers.", "search_blob": "lithium orotate lithium-orotate otc lithium low-dose lithium li-orotate lithium orotate 5 mg elemental lithium supplement lithium orotate lithium oratate li orotate otc lithium 5 mg lithium yankner lithium orotate microdose lithium yankner mood mineral alzheimers lithium mood longevity / alzheimer\u2019s talk microdose lithium vs psychiatric lithium carbonate orotate microdose lithium yankner mood mineral 5 mg lithium alzheimers lithium lithium orotate is a lithium salt sold as an oral supplement for mood-related purposes; elemental lithium and total salt weight are different label numbers. lithium orotate is an oral lithium salt sold as a supplement. mood accounts include subtle calm, no effect, agitation, emotional flattening and unwanted sleep or urinary changes. elemental lithium and total salt weight are different quantities. alzheimer\u2019s research headlines do not establish human supplement prevention or reversal. cognitive research compounds non-peptide systemic systemic oral lithium salt sold as a supplement. systemic whole-body circulating", "legal_class": null }, { "id": 254, "slug": "l-theanine", "name": "L-theanine", "aliases": [ "theanine", "Suntheanine", "L theanine", "N-ethyl-L-glutamine", "tea theanine" ], "type": "Non-peptide", "category": "Cognitive research compounds", "goals_use_cases": [ "cognition", "calm focus", "caffeine stack", "sleep onset", "anxiety-adjacent talk" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "l-theanine", "theanine", "l theanine", "suntheanine", "theanine coffee", "theanine sleep", "coffee stack", "calm caffeine", "alpha waves", "sleep amino", "tea" ], "feel_search": [ "coffee stack", "suntheanine", "calm caffeine", "alpha waves", "sleep amino", "tea" ], "summary": "L-theanine is an amino acid found in tea, used as a supplement for calmer focus with caffeine or for relaxation before sleep.", "search_blob": "l-theanine l-theanine theanine suntheanine l theanine n-ethyl-l-glutamine tea theanine l-theanine theanine l theanine suntheanine theanine coffee theanine sleep coffee stack calm caffeine alpha waves sleep amino tea cognition calm focus caffeine stack sleep onset anxiety-adjacent talk coffee stack suntheanine calm caffeine alpha waves sleep amino tea l-theanine is an amino acid found in tea, used as a supplement for calmer focus with caffeine or for relaxation before sleep. some reports describe subtle relief from jitters; others describe marked relaxation, unwanted sedation or no noticeable calm. reported duration ranges from a few hours to an all-day impression, with caffeine and other ingredients complicating attribution. l-theanine is a tea amino acid discussed for calmer attention or sleep. reports also include no benefit, sedation, emotional flattening and worse mornings. the 200 mg capsule also appears in night stacks next to magnesium. coffee-pairing notes discuss 100\u2013200 mg and bedtime notes 200\u2013400 mg; these reported amounts are not a dosing ceiling. cognitive research compounds non-peptide systemic systemic amino acid from tea. systemic whole-body circulating", "legal_class": null }, { "id": 255, "slug": "9-me-bc", "name": "9-Me-BC", "aliases": [ "9-methyl-\u03b2-carboline", "9-MBC", "9MeBC", "9-methyl-beta-carboline" ], "type": "Non-peptide", "category": "Cognitive research compounds", "goals_use_cases": [ "cognition", "dopamine-related claims (unverified)", "anhedonia after stimulant use (reported)", "motivation / social-effect reports", "Parkinson\u2019s-related discussion" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "9-me-bc", "9mebc", "9-mbc", "9 methyl beta carboline", "9-methyl-b-carboline", "9 me bc", "dopamine restoration talk", "post-stim anhedonia", "motivation / social", "Parkinson-adjacent lore", "dopamine restore", "photosensitivity", "anhedonia", "9mbc", "after adderall", "beta carboline" ], "feel_search": [ "dopamine restore", "photosensitivity", "anhedonia", "9mbc", "after adderall", "beta carboline" ], "summary": "9-Me-BC (9-methyl-\u03b2-carboline) is a research nootropic discussed for motivation and mood.", "search_blob": "9-me-bc 9-me-bc 9-methyl-\u03b2-carboline 9-mbc 9mebc 9-methyl-beta-carboline 9-me-bc 9mebc 9-mbc 9 methyl beta carboline 9-methyl-b-carboline 9 me bc dopamine restoration talk post-stim anhedonia motivation / social parkinson-adjacent lore dopamine restore photosensitivity anhedonia 9mbc after adderall beta carboline cognition dopamine-related claims (unverified) anhedonia after stimulant use (reported) motivation / social-effect reports parkinson\u2019s-related discussion dopamine restore photosensitivity anhedonia 9mbc after adderall beta carboline 9-me-bc (9-methyl-\u03b2-carboline) is a research nootropic discussed for motivation and mood. reports include renewed enjoyment, nonresponse, insomnia and severe mood or perception symptoms. a detailed log includes volatile mood with bromantane, caffeine and other co-use, which obscures attribution. 9-me-bc is an experimental beta-carboline discussed for motivation and enjoyment. reports include benefit, nonresponse and adverse mood or perception changes. 15 mg appears in cycle reports. photosensitivity is a concern; these reports do not establish human safety or a restoration protocol. cognitive research compounds non-peptide systemic systemic beta-carboline; oral and sublingual reports. systemic whole-body circulating", "legal_class": null }, { "id": 256, "slug": "empagliflozin", "name": "Empagliflozin", "aliases": [ "Jardiance", "SGLT2 inhibitor empagliflozin", "empa", "Jardiance 10 mg", "Jardiance 25 mg" ], "type": "Non-peptide", "category": "Metabolic & longevity adjacents", "goals_use_cases": [ "longevity / SGLT2 talk", "glucose", "heart / kidney labeled talk", "vs metformin" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "empagliflozin", "jardiance", "sglt2", "empagloflozin", "jardiance 10", "flozin", "yeast", "attia", "pee sugar" ], "feel_search": [ "jardiance", "sglt2", "flozin", "yeast", "attia", "pee sugar" ], "summary": "Empagliflozin (Jardiance) is an SGLT2-inhibitor tablet that increases glucose loss in urine, used in diabetes, heart-failure and kidney care.", "search_blob": "empagliflozin empagliflozin jardiance sglt2 inhibitor empagliflozin empa jardiance 10 mg jardiance 25 mg empagliflozin jardiance sglt2 empagloflozin jardiance 10 flozin yeast attia pee sugar longevity / sglt2 talk glucose heart / kidney labeled talk vs metformin jardiance sglt2 flozin yeast attia pee sugar empagliflozin (jardiance) is an sglt2-inhibitor tablet that increases glucose loss in urine, used in diabetes, heart-failure and kidney care. people discuss more urination and thirst, some with recurrent genital yeast symptoms, while others report good glucose control without problems. empagliflozin, sold as jardiance, is an oral prescription sglt2 inhibitor that lets more glucose leave in urine. medical heart/kidney indications are distinct from healthy-user longevity claims. people report better readings, no change, thirst, infections or fatigue. ketoacidosis can occur without very high glucose. metabolic & longevity adjacents non-peptide systemic systemic oral sglt2 inhibitor. systemic whole-body circulating", "legal_class": null }, { "id": 257, "slug": "vesilute", "name": "Vesilute", "aliases": [ "ED peptide", "Glu-Asp", "bladder cytogen", "Glu-Asp dipeptide", "H-Glu-Asp-OH", "ED dipeptide", "Vesilut", "Khavinson bladder peptide", "A-12 synthetic counterpart" ], "type": "Peptide", "category": "Organ bioregulators", "goals_use_cases": [ "bladder / urinary comfort (discussed)", "nocturia / overactive-bladder talk", "prostate-adjacent urinary flow talk", "BPH-adjacent community stacks", "longevity / organ-bioregulator calendars" ], "delivery_methods": [ "oral", "subcutaneous" ], "discussion_popularity": "Emerging", "reach": "Mixed", "misspellings_search_terms": [ "vesilute", "vesilut", "glu-asp", "ed peptide", "bladder bioregulator", "vesilute dosage", "vesilute vs vesugen", "vesilute vs visoluten", "bladder / urinary comfort (discussed)", "nocturia / overactive-bladder talk", "prostate-adjacent urinary flow talk", "bph-adjacent community stacks", "longevity / organ-bioregulator calendars" ], "feel_search": [ "bladder / urinary comfort (discussed)", "nocturia / overactive-bladder talk", "prostate-adjacent urinary flow talk", "bph-adjacent community stacks", "longevity / organ-bioregulator calendars" ], "summary": "Vesilute is the synthetic Glu-Asp dipeptide, marketed in the Russian bioregulator tradition for bladder and urogenital support.", "search_blob": "vesilute vesilute ed peptide glu-asp bladder cytogen glu-asp dipeptide h-glu-asp-oh ed dipeptide vesilut khavinson bladder peptide a-12 synthetic counterpart vesilute vesilut glu-asp ed peptide bladder bioregulator vesilute dosage vesilute vs vesugen vesilute vs visoluten bladder / urinary comfort (discussed) nocturia / overactive-bladder talk prostate-adjacent urinary flow talk bph-adjacent community stacks longevity / organ-bioregulator calendars bladder / urinary comfort (discussed) nocturia / overactive-bladder talk prostate-adjacent urinary flow talk bph-adjacent community stacks longevity / organ-bioregulator calendars bladder / urinary comfort (discussed) nocturia / overactive-bladder talk prostate-adjacent urinary flow talk bph-adjacent community stacks longevity / organ-bioregulator calendars vesilute is the synthetic glu-asp dipeptide, marketed in the russian bioregulator tradition for bladder and urogenital support. one prostamax/vesilute user described less pain and fewer nighttime bathroom trips, with better sleep; the two-product result cannot isolate vesilute. vesilute is synthetic glu-asp, discussed for urinary symptoms. sparse positive reports involve other products or prior pelvic-health treatment and do not establish a predictable onset. not oxybutynin, not tamsulosin, not a pelvic-floor program, not a uti antibiotic. organ bioregulators peptide mixed marketed for bladder support; reported products and routes vary, and positive accounts often omit the route. mixed local systemic", "legal_class": null }, { "id": 258, "slug": "chitomur", "name": "Chitomur", "aliases": [ "A-12", "bladder cytomax", "A-12 bladder bioregulator", "Khavinson bladder complex", "Chitomur peptide" ], "type": "Peptide", "category": "Organ bioregulators", "goals_use_cases": [ "bladder / urinary comfort (discussed)", "overactive-bladder talk", "nocturia talk", "BPH-adjacent community stacks", "longevity / organ-bioregulator calendars" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "chitomur", "chitomur peptide", "a-12 bioregulator", "a12 bladder", "chitomur dosage", "chitomur vs vesilute", "bladder / urinary comfort (discussed)", "overactive-bladder talk", "nocturia talk", "bph-adjacent community stacks", "longevity / organ-bioregulator calendars" ], "feel_search": [ "bladder / urinary comfort (discussed)", "overactive-bladder talk", "nocturia talk", "bph-adjacent community stacks", "longevity / organ-bioregulator calendars" ], "summary": "Chitomur is an animal-bladder peptide complex sold as a bioregulator for urinary symptoms, distinct from the single peptide Vesilute.", "search_blob": "chitomur chitomur a-12 bladder cytomax a-12 bladder bioregulator khavinson bladder complex chitomur peptide chitomur chitomur peptide a-12 bioregulator a12 bladder chitomur dosage chitomur vs vesilute bladder / urinary comfort (discussed) overactive-bladder talk nocturia talk bph-adjacent community stacks longevity / organ-bioregulator calendars bladder / urinary comfort (discussed) overactive-bladder talk nocturia talk bph-adjacent community stacks longevity / organ-bioregulator calendars bladder / urinary comfort (discussed) overactive-bladder talk nocturia talk bph-adjacent community stacks longevity / organ-bioregulator calendars chitomur is an animal-bladder peptide complex sold as a bioregulator for urinary symptoms, distinct from the single peptide vesilute. one tablet user reported improvement with continuing bladder tension; other users reported no benefit. a retailer-page reviewer described bladder pain during separate attempts, with pre-existing illness and earlier co-use complicating attribution. chitomur is an animal-bladder peptide mixture discussed for urinary symptoms. reports include improvement, nonresponse and pain; they do not demonstrate bladder repair. natural short-peptide complex from bladder tissue in the khavinson cytomax line, catalogued as a-12. not a single named amino-acid sequence like vesilute. organ bioregulators peptide systemic oral tissue-peptide complex marketed for bladder symptoms; selective bladder delivery is not established here. systemic whole-body circulating", "legal_class": null }, { "id": 259, "slug": "chelohart", "name": "Chelohart", "aliases": [ "A-14", "heart cytomax", "A-14 heart bioregulator", "Khavinson heart complex", "Chelohart peptide" ], "type": "Peptide", "category": "Organ bioregulators", "goals_use_cases": [ "cardiovascular / heart-tissue talk", "longevity / organ-bioregulator calendars", "PVC / palpitations curiosity (community)", "post-stress heart-support narratives" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "chelohart", "chelohart peptide", "a-14 bioregulator", "a14 heart", "chelohart dosage", "chelohart vs cardiogen", "cardiovascular / heart-tissue talk", "longevity / organ-bioregulator calendars", "pvc / palpitations curiosity (community)", "post-stress heart-support narratives" ], "feel_search": [ "cardiovascular / heart-tissue talk", "longevity / organ-bioregulator calendars", "pvc / palpitations curiosity (community)", "post-stress heart-support narratives" ], "summary": "Chelohart is an oral young-animal heart-tissue peptide mixture marketed as Cytomax A-14. Reports concern wearable changes and recovery claims alongside other treatments.", "search_blob": "chelohart chelohart a-14 heart cytomax a-14 heart bioregulator khavinson heart complex chelohart peptide chelohart chelohart peptide a-14 bioregulator a14 heart chelohart dosage chelohart vs cardiogen cardiovascular / heart-tissue talk longevity / organ-bioregulator calendars pvc / palpitations curiosity (community) post-stress heart-support narratives cardiovascular / heart-tissue talk longevity / organ-bioregulator calendars pvc / palpitations curiosity (community) post-stress heart-support narratives cardiovascular / heart-tissue talk longevity / organ-bioregulator calendars pvc / palpitations curiosity (community) post-stress heart-support narratives chelohart is an oral young-animal heart-tissue peptide mixture marketed as cytomax a-14. reports concern wearable changes and recovery claims alongside other treatments. one user reports better wearable heart-rate, hrv and sleep scores during a month combining chelohart, svetinorm and ventfort. the three-product stack prevents attribution. chelohart is an oral young-animal heart-tissue peptide mixture marketed as cytomax a-14. reports concern wearable changes and recovery claims alongside other treatments. a month-long chelohart, svetinorm and ventfort account cannot isolate chelohart. unquantified secondhand recovery stories do not establish repaired heart tissue. organ bioregulators peptide systemic an oral tissue-derived mixture marketed for heart support; targeted delivery to heart muscle is not established. systemic whole-body circulating", "legal_class": null }, { "id": 260, "slug": "glandokort", "name": "Glandokort", "aliases": [ "A-17", "adrenal cytomax", "A-17 adrenal bioregulator", "Khavinson adrenal complex", "Glandokort peptide" ], "type": "Peptide", "category": "Organ bioregulators", "goals_use_cases": [ "stress / adrenal-fatigue talk (community)", "energy / burnout narratives", "longevity / organ-bioregulator calendars", "hormone-axis neighbor stacks" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "glandokort", "glandokort peptide", "a-17 bioregulator", "a17 adrenal", "glandokort dosage", "adrenal cytomax", "stress / adrenal-fatigue talk (community)", "energy / burnout narratives", "longevity / organ-bioregulator calendars", "hormone-axis neighbor stacks" ], "feel_search": [ "stress / adrenal-fatigue talk (community)", "energy / burnout narratives", "longevity / organ-bioregulator calendars", "hormone-axis neighbor stacks" ], "summary": "Glandokort is an adrenal-tissue peptide extract sold in capsules; people look it up for stress and low-energy complaints.", "search_blob": "glandokort glandokort a-17 adrenal cytomax a-17 adrenal bioregulator khavinson adrenal complex glandokort peptide glandokort glandokort peptide a-17 bioregulator a17 adrenal glandokort dosage adrenal cytomax stress / adrenal-fatigue talk (community) energy / burnout narratives longevity / organ-bioregulator calendars hormone-axis neighbor stacks stress / adrenal-fatigue talk (community) energy / burnout narratives longevity / organ-bioregulator calendars hormone-axis neighbor stacks stress / adrenal-fatigue talk (community) energy / burnout narratives longevity / organ-bioregulator calendars hormone-axis neighbor stacks glandokort is an adrenal-tissue peptide extract sold in capsules; people look it up for stress and low-energy complaints. glandokort is an adrenal-tissue peptide mixture discussed for stress and low energy. reports include improvement, uncertain benefit, anxiety and disrupted sleep; they do not establish adrenal recovery. not pregnenolone, not hpa-axis bloodwork, not a license to stop prescribed steroids. organ bioregulators peptide systemic marketed for adrenal support; oral use does not demonstrate that the mixture reaches adrenal tissue intact. systemic whole-body circulating", "legal_class": null }, { "id": 261, "slug": "taxorest", "name": "Taxorest", "aliases": [ "A-19", "lung cytomax", "A-19 lung bioregulator", "bronchial cytomax", "Khavinson lung complex", "Taxorest peptide" ], "type": "Peptide", "category": "Organ bioregulators", "goals_use_cases": [ "respiratory / lung-support talk", "chronic bronchitis adjunct talk", "longevity / organ-bioregulator calendars", "breathing-comfort narratives" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "taxorest", "taxorest peptide", "a-19 bioregulator", "a19 lung", "taxorest dosage", "taxorest vs chonluten", "respiratory / lung-support talk", "chronic bronchitis adjunct talk", "longevity / organ-bioregulator calendars", "breathing-comfort narratives" ], "feel_search": [ "respiratory / lung-support talk", "chronic bronchitis adjunct talk", "longevity / organ-bioregulator calendars", "breathing-comfort narratives" ], "summary": "Taxorest (A-19) is a bronchial-mucosa-derived peptide mixture marketed for respiratory support, distinct from Chonluten and Bronchogen.", "search_blob": "taxorest taxorest a-19 lung cytomax a-19 lung bioregulator bronchial cytomax khavinson lung complex taxorest peptide taxorest taxorest peptide a-19 bioregulator a19 lung taxorest dosage taxorest vs chonluten respiratory / lung-support talk chronic bronchitis adjunct talk longevity / organ-bioregulator calendars breathing-comfort narratives respiratory / lung-support talk chronic bronchitis adjunct talk longevity / organ-bioregulator calendars breathing-comfort narratives respiratory / lung-support talk chronic bronchitis adjunct talk longevity / organ-bioregulator calendars breathing-comfort narratives taxorest (a-19) is a bronchial-mucosa-derived peptide mixture marketed for respiratory support, distinct from chonluten and bronchogen. accounts describe easier breathing, stairs or less cough during combined use. they also include product switching, smoking cessation, diet or other peptides, preventing taxorest-only attribution. taxorest is an animal bronchial-tissue peptide mixture discussed for breathing comfort. a 2-year, 3-times-per-year account reports improvement with other products, without isolating taxorest. not a rescue inhaler, steroid, oxygen, or antifibrotic. organ bioregulators peptide systemic systemic oral animal-lung tissue peptide extract sold as organ-targeted support; human efficacy and pharmacokinetics remain very thin. systemic whole-body circulating", "legal_class": null }, { "id": 262, "slug": "zhenoluten", "name": "Zhenoluten", "aliases": [ "A-15", "Jenoluten", "ovary cytomax", "A-15 ovary bioregulator", "Khavinson ovary complex", "Zhenoluten peptide" ], "type": "Peptide", "category": "Organ bioregulators", "goals_use_cases": [ "female reproductive / ovarian talk", "perimenopause / cycle-regularity narratives", "longevity / organ-bioregulator calendars" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "zhenoluten", "jenoluten", "zhenoluten peptide", "a-15 bioregulator", "a15 ovary", "zhenoluten dosage", "female reproductive / ovarian talk", "perimenopause / cycle-regularity narratives", "longevity / organ-bioregulator calendars" ], "feel_search": [ "female reproductive / ovarian talk", "perimenopause / cycle-regularity narratives", "longevity / organ-bioregulator calendars" ], "summary": "Zhenoluten, also spelled Jenoluten, is an ovarian-tissue-derived peptide mixture marketed for ovarian and menstrual-cycle support.", "search_blob": "zhenoluten zhenoluten a-15 jenoluten ovary cytomax a-15 ovary bioregulator khavinson ovary complex zhenoluten peptide zhenoluten jenoluten zhenoluten peptide a-15 bioregulator a15 ovary zhenoluten dosage female reproductive / ovarian talk perimenopause / cycle-regularity narratives longevity / organ-bioregulator calendars female reproductive / ovarian talk perimenopause / cycle-regularity narratives longevity / organ-bioregulator calendars female reproductive / ovarian talk perimenopause / cycle-regularity narratives longevity / organ-bioregulator calendars zhenoluten, also spelled jenoluten, is an ovarian-tissue-derived peptide mixture marketed for ovarian and menstrual-cycle support. one fertility-forum user reported stronger nails but uncertain, temporary changes in follicle counts while trying several treatments. zhenoluten, or jenoluten, is an oral ovarian-tissue peptide mixture marketed as cytomax a-15. it is discussed for cycle changes, perimenopause and fertility preparation. organ bioregulators peptide systemic an oral tissue-derived mixture marketed for ovarian support, without established selective delivery to the ovaries. systemic whole-body circulating", "legal_class": null }, { "id": 263, "slug": "bonothyrk", "name": "Bonothyrk", "aliases": [ "A-21", "Bonotirk", "parathyroid cytomax", "A-21 parathyroid bioregulator", "Khavinson parathyroid complex", "Bonothyrk peptide" ], "type": "Peptide", "category": "Organ bioregulators", "goals_use_cases": [ "bone / calcium-balance talk", "parathyroid-support narratives", "longevity / organ-bioregulator calendars" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "bonothyrk", "bonotirk", "bonothyrk peptide", "a-21 bioregulator", "a21 parathyroid", "bonothyrk dosage", "bone / calcium-balance talk", "parathyroid-support narratives", "longevity / organ-bioregulator calendars" ], "feel_search": [ "bone / calcium-balance talk", "parathyroid-support narratives", "longevity / organ-bioregulator calendars" ], "summary": "Bonothyrk (Bonotirk) is a parathyroid-derived peptide complex sold as a bioregulator, distinct from PTH hormone drugs or calcium supplements.", "search_blob": "bonothyrk bonothyrk a-21 bonotirk parathyroid cytomax a-21 parathyroid bioregulator khavinson parathyroid complex bonothyrk peptide bonothyrk bonotirk bonothyrk peptide a-21 bioregulator a21 parathyroid bonothyrk dosage bone / calcium-balance talk parathyroid-support narratives longevity / organ-bioregulator calendars bone / calcium-balance talk parathyroid-support narratives longevity / organ-bioregulator calendars bone / calcium-balance talk parathyroid-support narratives longevity / organ-bioregulator calendars bonothyrk (bonotirk) is a parathyroid-derived peptide complex sold as a bioregulator, distinct from pth hormone drugs or calcium supplements. the inspected material includes a promotional post, multi-bioregulator enthusiasm and a brief customer recommendation. none supplies an isolated bonothyrk symptom change, onset or follow-up result. bonothyrk is an a-21 parathyroid-tissue peptide mixture marketed for bone and calcium support. the inspected enthusiasm and suggestions supply no isolated product outcome. thyreogen is thyroid. bonothyrk is parathyroid. different glands, both \u201cthyr-\u201d in the catalog. organ bioregulators peptide systemic marketed for parathyroid support; a swallowed tissue complex does not establish selective gland delivery. systemic whole-body circulating", "legal_class": null }, { "id": 264, "slug": "amlexanox", "name": "Amlexanox", "aliases": [ "Aphthasol", "TBK1 IKK\u03b5 inhibitor", "CHX 3673", "amlexanox oral" ], "type": "Non-peptide", "category": "Metabolic & longevity adjacents", "goals_use_cases": [ "fat loss / recomp talk", "insulin-sensitivity talk", "NAFLD / liver-fat curiosity", "inflammation-metabolic research" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "amlexanox", "amlexanox dosage", "aphthasol oral", "tbk1 inhibitor", "amlexanox fat loss", "amlex", "fat loss / recomp talk", "insulin-sensitivity talk", "nafld / liver-fat curiosity", "inflammation-metabolic research" ], "feel_search": [ "fat loss / recomp talk", "insulin-sensitivity talk", "nafld / liver-fat curiosity", "inflammation-metabolic research" ], "summary": "Amlexanox is a small-molecule drug once used in canker-sore paste and now discussed for inflammation, metabolism and mast-cell symptoms.", "search_blob": "amlexanox amlexanox aphthasol tbk1 ikk\u03b5 inhibitor chx 3673 amlexanox oral amlexanox amlexanox dosage aphthasol oral tbk1 inhibitor amlexanox fat loss amlex fat loss / recomp talk insulin-sensitivity talk nafld / liver-fat curiosity inflammation-metabolic research fat loss / recomp talk insulin-sensitivity talk nafld / liver-fat curiosity inflammation-metabolic research fat loss / recomp talk insulin-sensitivity talk nafld / liver-fat curiosity inflammation-metabolic research amlexanox is a small-molecule drug once used in canker-sore paste and now discussed for inflammation, metabolism and mast-cell symptoms. reports include skin or food-tolerance improvement, nonresponse and unwanted activation or gut effects. one nonresponder later withdrew an initial sedation attribution because stopping and restarting did not change it. amlexanox is discussed for metabolic and mast-cell symptoms. older reports describe appearance changes at 3\u20135 weeks; others report no benefit or adverse effects, and the randomized study found no significant weight-loss difference. reports include skin improvement, nonresponse, gut symptoms, rash and activation. swallowed products are distinct from historic mouth-ulcer paste. metabolic & longevity adjacents non-peptide systemic swallowed products have systemic exposure; mouth-ulcer paste and different capsule release forms are not interchangeable. systemic whole-body circulating", "legal_class": null }, { "id": 265, "slug": "c60", "name": "C60", "aliases": [ "carbon 60", "fullerene", "buckminsterfullerene", "buckyballs", "C60-OO", "C60 olive oil" ], "type": "Non-peptide", "category": "Longevity & cellular energy", "goals_use_cases": [ "longevity / antioxidant talk", "C60-in-olive-oil biohack", "mitochondrial / energy narratives" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "c60", "c-60", "carbon 60", "fullerene", "buckyballs", "c60 olive oil", "c60 dosage", "buckminsterfullerene", "longevity / antioxidant talk", "mitochondrial / energy narratives", "c60-in-olive-oil biohack" ], "feel_search": [ "longevity / antioxidant talk", "mitochondrial / energy narratives", "c60-in-olive-oil biohack" ], "summary": "C60 is a 60-carbon fullerene molecule, commonly discussed in olive-oil preparations for experimental longevity use.", "search_blob": "c60 c60 carbon 60 fullerene buckminsterfullerene buckyballs c60-oo c60 olive oil c60 c-60 carbon 60 fullerene buckyballs c60 olive oil c60 dosage buckminsterfullerene longevity / antioxidant talk mitochondrial / energy narratives c60-in-olive-oil biohack longevity / antioxidant talk c60-in-olive-oil biohack mitochondrial / energy narratives longevity / antioxidant talk mitochondrial / energy narratives c60-in-olive-oil biohack c60 is a 60-carbon fullerene molecule, commonly discussed in olive-oil preparations for experimental longevity use. one long-term user reports no appreciable effect; another describes better cardio and minor changes while rejecting cure-all claims. these accounts do not measure lifespan. c60 is a carbon cage molecule discussed in experimental oral oils for longevity. human reports range from perceived stamina gains to no benefit and adverse symptoms. oral c60 oil and topical fullerene cosmetics are separate uses; neither animal lifespan findings nor subjective energy reports establish longer human life. longevity & cellular energy non-peptide systemic oral oil preparations are discussed for systemic effects; their human distribution is not established here. systemic whole-body circulating", "legal_class": null }, { "id": 266, "slug": "zinc-l-carnosine", "name": "Zinc L-carnosine", "aliases": [ "polaprezinc", "PepZin GI", "zinc carnosine", "ZnC", "zinc-carnosine" ], "type": "Non-peptide", "category": "Gut & inflammation peptides", "goals_use_cases": [ "gut lining / gastritis talk", "leaky-gut / permeability narratives", "ulcer-adjunct discussion" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Mixed", "misspellings_search_terms": [ "zinc l-carnosine", "zinc carnosine", "pepzin gi", "polaprezinc", "znc", "zinc-carnosine dosage", "gastritis flare", "pepzin", "empty stomach", "gut lining", "leaky gut", "zinc burn", "not bpc" ], "feel_search": [ "gastritis flare", "pepzin", "empty stomach", "gut lining", "leaky gut", "zinc burn", "not bpc" ], "summary": "Zinc L-carnosine, or polaprezinc, is a zinc\u2013carnosine complex used in gastric-mucosal treatment and sold in gut-health supplements.", "search_blob": "zinc l-carnosine zinc-l-carnosine polaprezinc pepzin gi zinc carnosine znc zinc-carnosine zinc l-carnosine zinc carnosine pepzin gi polaprezinc znc zinc-carnosine dosage gastritis flare pepzin empty stomach gut lining leaky gut zinc burn not bpc gut lining / gastritis talk leaky-gut / permeability narratives ulcer-adjunct discussion gastritis flare pepzin empty stomach gut lining leaky gut zinc burn not bpc zinc l-carnosine, or polaprezinc, is a zinc\u2013carnosine complex used in gastric-mucosal treatment and sold in gut-health supplements. one person described less stomach pain and reflux while continuing other treatment; another reported an immediate flare and stopped. zinc l-carnosine is an oral compound people look up for gut. some call it the thing that let them eat again; some flare. one account used 75 mg complex twice daily. doctor's best lists 75 mg complex per two capsules, including 16 mg elemental zinc; capsule count and zinc exposure must remain distinct. gut & inflammation peptides non-peptide mixed oral capsules and chewable products discussed for gut comfort, with elemental zinc contributing to total zinc exposure. mixed local systemic", "legal_class": null }, { "id": 267, "slug": "tributyrin", "name": "Tributyrin", "aliases": [ "glyceryl tributyrate", "CoreBiome", "butyrate triglyceride", "tributyrin butyrate" ], "type": "Non-peptide", "category": "Gut health & recovery", "goals_use_cases": [ "gut lining / butyrate talk", "SIBO / dysbiosis adjunct narratives", "gut-mood n=1 logs" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Mixed", "misspellings_search_terms": [ "tributyrin", "tributyrin dosage", "corebiome", "butyrate triglyceride", "glyceryl tributyrate", "tributyrin vs sodium butyrate", "gut lining / butyrate talk", "sibo / dysbiosis adjunct narratives", "gut-mood n=1 logs" ], "feel_search": [ "gut lining / butyrate talk", "sibo / dysbiosis adjunct narratives", "gut-mood n=1 logs" ], "summary": "Tributyrin joins three butyrate molecules to glycerol and is sold as an oral butyrate-delivering compound for gut-related interests.", "search_blob": "tributyrin tributyrin glyceryl tributyrate corebiome butyrate triglyceride tributyrin butyrate tributyrin tributyrin dosage corebiome butyrate triglyceride glyceryl tributyrate tributyrin vs sodium butyrate gut lining / butyrate talk sibo / dysbiosis adjunct narratives gut-mood n=1 logs gut lining / butyrate talk sibo / dysbiosis adjunct narratives gut-mood n=1 logs gut lining / butyrate talk sibo / dysbiosis adjunct narratives gut-mood n=1 logs tributyrin joins three butyrate molecules to glycerol and is sold as an oral butyrate-delivering compound for gut-related interests. accounts include easier bowel movements and less pain, partial relief or relapse, and adverse diarrhea or constipation. one brief clarity-and-mood lift was followed by anxiety, insomnia and diarrhea, leading the person to stop. tributyrin delivers butyrate during digestion and is discussed for gut symptoms. reports include improved bowel movements, partial relief, relapse, diarrhea and worse constipation. not a probiotic, not rifaximin, not a peptide. gut health & recovery non-peptide mixed oral butyrate-delivering compound; gut, mood and brain-fog reports have variable outcomes. mixed local systemic", "legal_class": null }, { "id": 268, "slug": "hyaluronic-acid", "name": "Hyaluronic acid", "aliases": [ "HA", "hyaluronan", "oral HA", "sodium hyaluronate", "hyaluronic acid pills" ], "type": "Non-peptide", "category": "Skin, hair & tissue remodeling", "goals_use_cases": [ "skin hydration / wrinkle talk", "joint comfort / OA-adjunct talk", "oral vs injection HA" ], "delivery_methods": [ "oral", "topical" ], "discussion_popularity": "Medium", "reach": "Mixed", "misspellings_search_terms": [ "hyaluronic acid", "hyaluronic acid dosage", "oral ha", "hyaluronan", "sodium hyaluronate", "ha pills", "hyaluronic acid joints", "120 mg", "knee shot", "serum dew", "not filler", "tret dryness", "blueprint", "mw fight" ], "feel_search": [ "oral ha", "120 mg", "knee shot", "serum dew", "not filler", "tret dryness", "blueprint", "mw fight" ], "summary": "Hyaluronic acid is a water-binding sugar polymer; oral supplements, skin serums and joint injections are different formulations used for hydration or joint symptoms.", "search_blob": "hyaluronic acid hyaluronic-acid ha hyaluronan oral ha sodium hyaluronate hyaluronic acid pills hyaluronic acid hyaluronic acid dosage oral ha hyaluronan sodium hyaluronate ha pills hyaluronic acid joints 120 mg knee shot serum dew not filler tret dryness blueprint mw fight skin hydration / wrinkle talk joint comfort / oa-adjunct talk oral vs injection ha oral ha 120 mg knee shot serum dew not filler tret dryness blueprint mw fight hyaluronic acid is a water-binding sugar polymer; oral supplements, skin serums and joint injections are different formulations used for hydration or joint symptoms. oral users report anything from improved skin hydration over weeks to no visible change after a year. that differs from the immediate surface feel of a serum. hyaluronic acid is a water-binding sugar polymer. oral users seek skin hydration or joint comfort, with reports ranging from improvement to no visible change after a year. capsules, surface serums, knee injections, skin boosters and fillers have different formulations, amounts and risks. skin, hair & tissue remodeling non-peptide mixed oral capsules, skin serums and injectable products have distinct routes; their results and amounts cannot be transferred between them. mixed local systemic", "legal_class": null }, { "id": 269, "slug": "myo-inositol-d-chiro-inositol", "name": "Myo-inositol / D-chiro-inositol", "aliases": [ "inositol", "myo-inositol", "D-chiro-inositol", "40:1 inositol", "MI/DCI", "inositol PCOS" ], "type": "Non-peptide", "category": "Metabolic & longevity adjacents", "goals_use_cases": [ "PCOS / cycle-regularity talk", "insulin-sensitivity talk", "sleep / Huberman-night add-on" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "inositol", "myo-inositol", "myoinositol", "d-chiro-inositol", "d chiro inositol", "40:1 inositol", "inositol pcos", "inositol dosage", "pcos / cycle-regularity talk", "insulin-sensitivity talk", "sleep / huberman-night add-on" ], "feel_search": [ "pcos / cycle-regularity talk", "insulin-sensitivity talk", "sleep / huberman-night add-on" ], "summary": "Myo-inositol and D-chiro-inositol are related nutrient compounds, often sold together in a 40:1 blend for PCOS and metabolic goals.", "search_blob": "myo-inositol / d-chiro-inositol myo-inositol-d-chiro-inositol inositol myo-inositol d-chiro-inositol 40:1 inositol mi/dci inositol pcos inositol myo-inositol myoinositol d-chiro-inositol d chiro inositol 40:1 inositol inositol pcos inositol dosage pcos / cycle-regularity talk insulin-sensitivity talk sleep / huberman-night add-on pcos / cycle-regularity talk insulin-sensitivity talk sleep / huberman-night add-on pcos / cycle-regularity talk insulin-sensitivity talk sleep / huberman-night add-on myo-inositol and d-chiro-inositol are related nutrient compounds, often sold together in a 40:1 blend for pcos and metabolic goals. reports describe changes in cravings, sleepiness or pms over weeks; some users report dizziness or stomach upset. menstrual-cycle changes are tracked over months. mi and dci are oral supplement ingredients discussed for pcos and sleep. reports include steadier cravings or later cycle changes, but also no benefit, sedation, anxiety and gastrointestinal effects. not metformin, not birth control, not a fertility drug label. metabolic & longevity adjacents non-peptide systemic oral powders and capsules, with distinct pcos and sleep-use histories and variable mi:dci composition. systemic whole-body circulating", "legal_class": null }, { "id": 270, "slug": "magnesium-l-threonate", "name": "Magnesium L-threonate", "aliases": [ "Magtein", "MgT", "magnesium threonate", "L-threonate magnesium" ], "type": "Non-peptide", "category": "Cognitive research compounds", "goals_use_cases": [ "sleep / Huberman-night stack", "cognition / memory talk", "vs magnesium glycinate" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "magnesium l-threonate", "magnesium threonate", "magtein", "mag l threonate", "magnesium threonate dosage", "huberman magnesium", "sleep / huberman-night stack", "cognition / memory talk", "vs magnesium glycinate" ], "feel_search": [ "sleep / huberman-night stack", "cognition / memory talk", "vs magnesium glycinate" ], "summary": "Magnesium L-threonate is a magnesium salt sold as Magtein, discussed for sleep and cognition; compound weight differs from elemental magnesium.", "search_blob": "magnesium l-threonate magnesium-l-threonate magtein mgt magnesium threonate l-threonate magnesium magnesium l-threonate magnesium threonate magtein mag l threonate magnesium threonate dosage huberman magnesium sleep / huberman-night stack cognition / memory talk vs magnesium glycinate sleep / huberman-night stack cognition / memory talk vs magnesium glycinate sleep / huberman-night stack cognition / memory talk vs magnesium glycinate magnesium l-threonate is a magnesium salt sold as magtein, discussed for sleep and cognition; compound weight differs from elemental magnesium. some feel sleepy, others notice little or gi discomfort. it is not reliably sedating: one long-time user described a few hours of mental energy and occasional overstimulation. magnesium l-threonate is an oral magnesium salt discussed for sleep and cognition. reports include clearer thinking, no benefit, disrupted sleep and next-day grogginess. discussion mixes 145 mg elemental magnesium, ambiguous 200\u2013400 mg threonate claims and the trial's 2 g whole-compound amount. they cannot be treated as equivalent. cognitive research compounds non-peptide systemic oral magnesium salt marketed for cognition and sleep; comparative benefit over glycinate is not established by the cited placebo trial. systemic whole-body circulating", "legal_class": null }, { "id": 271, "slug": "gt20029", "name": "GT20029", "aliases": [ "GT-20029", "Kintor GT20029", "topical AR PROTAC", "GT 20029", "androgen receptor degrader topical", "Kintor hair PROTAC" ], "type": "Non-peptide", "category": "Skin, hair & tissue remodeling", "goals_use_cases": [ "skin/hair", "androgenetic alopecia / topical AR degradation", "finasteride-avoid topical add-on", "pyrilutamide / RU-58841 comparison", "twice-weekly scalp routine talk" ], "delivery_methods": [ "topical" ], "discussion_popularity": "High", "reach": "Local", "misspellings_search_terms": [ "gt20029", "gt-20029", "gt 20029", "kintor protac", "ar degrader hair", "gt20029 topical", "hair", "scalp", "dht", "androgen receptor", "tressless", "new fin", "shedding" ], "feel_search": [ "hair", "scalp", "dht", "androgen receptor", "tressless", "new fin", "shedding" ], "summary": "GT20029 is an experimental topical androgen-receptor degrader being studied for pattern hair loss; it works differently from finasteride.", "search_blob": "gt20029 gt20029 gt-20029 kintor gt20029 topical ar protac gt 20029 androgen receptor degrader topical kintor hair protac gt20029 gt-20029 gt 20029 kintor protac ar degrader hair gt20029 topical hair scalp dht androgen receptor tressless new fin shedding skin/hair androgenetic alopecia / topical ar degradation finasteride-avoid topical add-on pyrilutamide / ru-58841 comparison twice-weekly scalp routine talk hair scalp dht androgen receptor tressless new fin shedding gt20029 is an experimental topical androgen-receptor degrader being studied for pattern hair loss; it works differently from finasteride. topical trial participants reported dryness, itching, rash, peeling or local discomfort. verified long-term consumer experience is sparse, so a typical diy response is unclear. gt20029 is an investigational topical androgen-receptor degrader discussed for hair preservation and regrowth. it works differently from dht-lowering drugs such as finasteride. a 12-week trial found signals in two arms, including 1% twice weekly. that does not establish a verified self-use response, half-life or long-term maintenance schedule. skin, hair & tissue remodeling non-peptide local a topical scalp formulation intended for local treatment; systemic effects are not ruled out. local site pin topical", "legal_class": null }, { "id": 272, "slug": "pp405", "name": "PP405", "aliases": [ "PP-405", "Pelage PP405", "PP 405", "MPC inhibitor hair gel" ], "type": "Non-peptide", "category": "Skin, hair & tissue remodeling", "goals_use_cases": [ "skin/hair", "androgenetic alopecia / dormant follicle talk", "minoxidil-alternative mechanism", "terminal hair from bald spots (discussed)", "gray-market identity fights" ], "delivery_methods": [ "topical" ], "discussion_popularity": "High", "reach": "Local", "misspellings_search_terms": [ "pp405", "pp-405", "suvomipic", "jxl069", "jxl-069", "pelage hair", "pp405 3hp", "dormant follicle gel", "Suvomipic", "JXL069", "JXL-069", "PP405-3HP", "hair", "bald", "dormant follicle", "tressless", "density" ], "feel_search": [ "hair", "bald", "dormant follicle", "tressless", "jxl069", "suvomipic", "density" ], "summary": "PP405 is an investigational topical small molecule that inhibits the mitochondrial pyruvate carrier, studied for hair regrowth.", "search_blob": "pp405 pp405 pp-405 pelage pp405 pp 405 mpc inhibitor hair gel pp405 pp-405 suvomipic jxl069 jxl-069 pelage hair pp405 3hp dormant follicle gel suvomipic jxl069 jxl-069 pp405-3hp hair bald dormant follicle tressless density skin/hair androgenetic alopecia / dormant follicle talk minoxidil-alternative mechanism terminal hair from bald spots (discussed) gray-market identity fights hair bald dormant follicle tressless jxl069 suvomipic density pp405 is an investigational topical small molecule that inhibits the mitochondrial pyruvate carrier, studied for hair regrowth. diy jxl069 reports range from early hair-quality changes to no meaningful regrowth; those products are not authenticated as pelage's pp405 gel. pp405 is pelage's investigational scalp gel targeting follicle-cell metabolism. outside jxl069/3hp accounts include improved hair appearance, no meaningful result and distressing shedding, without authenticated gel equivalence. the 31% headline is a responder proportion within a male subgroup, not a mean density gain. outside-product identities and formulations remain unverified. skin, hair & tissue remodeling non-peptide local local \u2014 a scalp gel. not a whole-body hormone. local site pin topical", "legal_class": null }, { "id": 273, "slug": "4-dma-78-dhf", "name": "4\u2032-DMA-7,8-DHF", "aliases": [ "4DMA", "Eutropoflavin", "4-DMA-7,8-DHF", "4-DMA", "4\u2032-dimethylamino-7,8-dihydroxyflavone", "4'-DMA-7,8-DHF", "7,8-DHF analog", "TrkB agonist flavone" ], "type": "Non-peptide", "category": "Cognitive research compounds", "goals_use_cases": [ "cognition", "mood / anhedonia talk", "BDNF / TrkB narratives", "sleep disruption (side)", "focus without stimulant feel (discussed)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "4dma", "4-dma", "4 dma", "eutropoflavin", "4-dma-7,8-dhf", "78dhf", "7,8 dhf analog", "trkb agonist", "mood", "focus", "brain fog", "sleep", "bdnf", "anhedonia", "social" ], "feel_search": [ "mood", "focus", "brain fog", "sleep", "bdnf", "anhedonia", "social" ], "summary": "4\u2032-DMA-7,8-DHF is a 7,8-DHF derivative sold as a research nootropic for mood and focus.", "search_blob": "4\u2032-dma-7,8-dhf 4-dma-78-dhf 4dma eutropoflavin 4-dma-7,8-dhf 4-dma 4\u2032-dimethylamino-7,8-dihydroxyflavone 4'-dma-7,8-dhf 7,8-dhf analog trkb agonist flavone 4dma 4-dma 4 dma eutropoflavin 4-dma-7,8-dhf 78dhf 7,8 dhf analog trkb agonist mood focus brain fog sleep bdnf anhedonia social cognition mood / anhedonia talk bdnf / trkb narratives sleep disruption (side) focus without stimulant feel (discussed) mood focus brain fog sleep bdnf anhedonia social 4\u2032-dma-7,8-dhf is a 7,8-dhf derivative sold as a research nootropic for mood and focus. reports include mood and attention benefits, nonresponse and unpleasant stimulation. one sublingual user's stronger later effect was followed by insomnia and next-day exhaustion; other users describe different timelines. 4\u2032-dma-7,8-dhf is a synthetic flavone discussed for mood and attention. reports include benefit, nonresponse, fog, unpleasant stimulation and prolonged sleep disruption. 8\u201310 mg morning appears in capsule notes. sleep disruption can extend late; people describe varied on/off patterns. cognitive research compounds non-peptide systemic systemic flavone discussed orally or sublingually; not a peptide injection. systemic whole-body circulating", "legal_class": null }, { "id": 274, "slug": "dim", "name": "DIM", "aliases": [ "Diindolylmethane", "3,3'-diindolylmethane", "BioResponse DIM", "3,3\u2019-Diindolylmethane", "I3C metabolite (discussed)", "cruciferous estrogen supplement" ], "type": "Non-peptide", "category": "Hormone modulators", "goals_use_cases": [ "estrogen metabolism talk", "TRT / high-E2 folklore", "hormonal acne", "hair / estrogen-dominance stacks", "PMS / women\u2019s hormone talk" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "dim", "diindolylmethane", "di-indolylmethane", "bioresponse dim", "i3c dim", "estrogen blocker dim", "estrogen", "e2", "acne", "trt", "pms", "water weight", "headache" ], "feel_search": [ "estrogen", "e2", "acne", "trt", "pms", "water weight", "headache" ], "summary": "DIM (3,3\u2032-diindolylmethane) is a crucifer-derived compound sold as a supplement and discussed for estrogen metabolism and acne.", "search_blob": "dim dim diindolylmethane 3,3'-diindolylmethane bioresponse dim 3,3\u2019-diindolylmethane i3c metabolite (discussed) cruciferous estrogen supplement dim diindolylmethane di-indolylmethane bioresponse dim i3c dim estrogen blocker dim estrogen e2 acne trt pms water weight headache estrogen metabolism talk trt / high-e2 folklore hormonal acne hair / estrogen-dominance stacks pms / women\u2019s hormone talk estrogen e2 acne trt pms water weight headache dim (3,3\u2032-diindolylmethane) is a crucifer-derived compound sold as a supplement and discussed for estrogen metabolism and acne. a pcos user describes fewer breakouts in week three and clearer skin by week four. that does not show that serum estradiol fell or that dim acts like an aromatase inhibitor. dim is an oral crucifer-derived supplement discussed for acne, pms and estrogen-related symptoms. it is not a predictable estrogen-lowering substitute for anastrozole. reports at 100\u2013200 mg with food include improvement, no benefit and unwanted symptoms. serum e2, urinary metabolites and subjective effects are separate endpoints. hormone modulators non-peptide systemic systemic oral \u2014 a capsule with food, not a scalp liquid or an ai pill. systemic whole-body circulating", "legal_class": null }, { "id": 275, "slug": "methylcobalamin", "name": "Methylcobalamin", "aliases": [ "Methyl B12", "MeCbl", "Vitamin B12 (methyl form)" ], "type": "Non-peptide", "category": "Longevity & cellular energy", "goals_use_cases": [ "energy / fatigue talk", "GLP-1 compounding add-on", "methylation / MTHFR folklore", "neuropathy talk", "vegan / metformin B12 gap" ], "delivery_methods": [ "oral", "intramuscular", "subcutaneous" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "methylcobalamin", "methyl cobalamin", "methyl b12", "b12", "b-12", "cyanocobalamin", "mecbl", "vitamin b12", "Vitamin B12", "B12", "cobalamin", "cyanocobalamin (often compounded instead)", "hydroxocobalamin (clinic cousin)", "adenosylcobalamin (discussed)", "energy", "fatigue", "methylation", "neuropathy", "glp", "pink urine" ], "feel_search": [ "energy", "fatigue", "b12", "methylation", "neuropathy", "glp", "pink urine" ], "summary": "Methylcobalamin is one form of vitamin B12, used to correct deficiency and discussed for energy; it is not a general stimulant or interchangeable with NAD+.", "search_blob": "methylcobalamin methylcobalamin methyl b12 mecbl vitamin b12 (methyl form) methylcobalamin methyl cobalamin methyl b12 b12 b-12 cyanocobalamin mecbl vitamin b12 vitamin b12 b12 cobalamin cyanocobalamin (often compounded instead) hydroxocobalamin (clinic cousin) adenosylcobalamin (discussed) energy fatigue methylation neuropathy glp pink urine energy / fatigue talk glp-1 compounding add-on methylation / mthfr folklore neuropathy talk vegan / metformin b12 gap energy fatigue b12 methylation neuropathy glp pink urine methylcobalamin is one form of vitamin b12, used to correct deficiency and discussed for energy; it is not a general stimulant or interchangeable with nad+. some notice little fatigue improvement; others report anxiety or mood changes after hours or weeks. a 'b12 buzz' does not establish deficiency or show that the product is helping. methylcobalamin is one form of b12. reports include better energy, persistent fatigue, anxiety and sleepiness; a buzz or nonresponse does not establish deficiency or explain the outcome. standalone tablets and injections, and b12 inside a combined glp product, are different records. a glp dose or draw volume alone does not reveal the methylcobalamin amount. longevity & cellular energy non-peptide systemic systemic vitamin, with distinct oral, sublingual and injectable formulations. systemic whole-body circulating", "legal_class": null }, { "id": 276, "slug": "ketoconazole", "name": "Ketoconazole", "aliases": [ "Nizoral", "keto shampoo", "ketoconazole 1%", "ketoconazole 2%", "Nizoral A-D", "topical keto" ], "type": "Non-peptide", "category": "Skin, hair & tissue remodeling", "goals_use_cases": [ "skin/hair", "dandruff / seborrheic dermatitis", "androgenetic alopecia add-on", "scalp oil / DHT folklore", "min/fin stack staple" ], "delivery_methods": [ "topical" ], "discussion_popularity": "High", "reach": "Local", "misspellings_search_terms": [ "ketoconazole", "nizoral", "keto shampoo", "ketokonazole", "nizorol", "2% keto", "dandruff", "itch", "hair", "oily scalp", "dry hair" ], "feel_search": [ "dandruff", "itch", "hair", "nizoral", "oily scalp", "dry hair" ], "summary": "Ketoconazole is an antifungal, usually discussed here as scalp shampoo for dandruff and itching or as a hair-loss adjunct; oral tablets are different.", "search_blob": "ketoconazole ketoconazole nizoral keto shampoo ketoconazole 1% ketoconazole 2% nizoral a-d topical keto ketoconazole nizoral keto shampoo ketokonazole nizorol 2% keto dandruff itch hair oily scalp dry hair skin/hair dandruff / seborrheic dermatitis androgenetic alopecia add-on scalp oil / dht folklore min/fin stack staple dandruff itch hair nizoral oily scalp dry hair ketoconazole is an antifungal, usually discussed here as scalp shampoo for dandruff and itching or as a hair-loss adjunct; oral tablets are different. some users describe reduced flakes or itch; others report no benefit, dryness or worsening irritation. one frequent-use account later had fewer flakes but continuing itch amid several treatment changes. ketoconazole is an antifungal discussed here mainly as scalp shampoo. reports include less flaking and itch, no benefit, and dry or irritated hair and scalp. the 1\u20132% shampoos in these accounts differ from oral tablets. concentration, contact time and wash frequency are separate exposure details, not a shared dosing instruction. skin, hair & tissue remodeling non-peptide local topical scalp shampoo in these accounts; oral tablets have different exposure and risks. local site pin topical", "legal_class": null }, { "id": 277, "slug": "spironolactone", "name": "Spironolactone", "aliases": [ "Spiro", "Aldactone", "spironolactone topical", "topical spiro", "Aldactone hair" ], "type": "Non-peptide", "category": "Skin, hair & tissue remodeling", "goals_use_cases": [ "skin/hair", "female-pattern hair / PCOS acne", "androgen-receptor block (discussed)", "topical anti-androgen DIY", "blood-pressure / potassium caution" ], "delivery_methods": [ "oral", "topical" ], "discussion_popularity": "High", "reach": "Mixed", "misspellings_search_terms": [ "spironolactone", "spiro", "aldactone", "spironolactone topical", "spirolactone", "aldactone hair", "acne", "hair", "pcos", "potassium", "peeing", "breast tenderness", "dizziness" ], "feel_search": [ "acne", "hair", "pcos", "potassium", "peeing", "breast tenderness", "dizziness" ], "summary": "Spironolactone is a prescription aldosterone blocker with antiandrogen activity, also discussed for acne and hair-related concerns.", "search_blob": "spironolactone spironolactone spiro aldactone spironolactone topical topical spiro aldactone hair spironolactone spiro aldactone spironolactone topical spirolactone aldactone hair acne hair pcos potassium peeing breast tenderness dizziness skin/hair female-pattern hair / pcos acne androgen-receptor block (discussed) topical anti-androgen diy blood-pressure / potassium caution acne hair pcos potassium peeing breast tenderness dizziness spironolactone is a prescription aldosterone blocker with antiandrogen activity, also discussed for acne and hair-related concerns. reports include less oily skin and calmer acne, but also dizziness, increased urination, spotting or genital discomfort. spironolactone is a prescription potassium-sparing diuretic with antiandrogen activity. people discuss oral tablets for acne and hair concerns, alongside separate topical scalp experiments. oral reports include 50\u2013100 mg/day, with both improvement and nonresponse. potassium, kidney function, blood pressure and hormonal effects are important cautions. skin, hair & tissue remodeling non-peptide mixed oral tablets act systemically. topical scalp creams and solutions are separate formulations with uncertain absorption. mixed local systemic", "legal_class": null }, { "id": 278, "slug": "tmg", "name": "TMG", "aliases": [ "Betaine", "Trimethylglycine", "betaine anhydrous", "Betaine anhydrous", "TMG betaine", "glycine betaine", "betaine TMG (not betaine HCl)" ], "type": "Non-peptide", "category": "Longevity & cellular energy", "goals_use_cases": [ "endurance", "methylation / homocysteine", "NMN / NR partner", "endurance / power (betaine sports studies)", "liver / fatty-liver adjacency", "GLP-1 / energy stack talk" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "tmg", "trimethylglycine", "betaine", "betaine anhydrous", "tmg betaine", "trimethyl glycine", "betaine hcl", "methylation", "homocysteine", "nmn", "fishy", "endurance", "pump" ], "feel_search": [ "methylation", "homocysteine", "nmn", "fishy", "endurance", "pump" ], "summary": "TMG is trimethylglycine, or betaine anhydrous, discussed for methylation and homocysteine; it differs from betaine HCl.", "search_blob": "tmg tmg betaine trimethylglycine betaine anhydrous betaine anhydrous tmg betaine glycine betaine betaine tmg (not betaine hcl) tmg trimethylglycine betaine betaine anhydrous tmg betaine trimethyl glycine betaine hcl methylation homocysteine nmn fishy endurance pump endurance methylation / homocysteine nmn / nr partner endurance / power (betaine sports studies) liver / fatty-liver adjacency glp-1 / energy stack talk methylation homocysteine nmn fishy endurance pump tmg is trimethylglycine, or betaine anhydrous, discussed for methylation and homocysteine; it differs from betaine hcl. one person describes clarity and motivation with morning use but difficulty sleeping later. other accounts include no benefit, sedation, anxiety or worse sleep; no reliable felt-duration window emerges. tmg is oral betaine anhydrous, discussed for methylation, homocysteine and performance. accounts include clarity, no benefit, sedation, anxiety and disrupted sleep. 500\u20131000 mg with the nad stack. 2\u20132.5 g is the older sports-betaine camp. not betaine hcl. longevity & cellular energy non-peptide systemic systemic oral \u2014 a powder or capsule. not a pin. systemic whole-body circulating", "legal_class": null }, { "id": 279, "slug": "luteolin", "name": "Luteolin", "aliases": [ "luteolin flavonoid", "CD38 luteolin", "Luteolin flavonoid", "3',4',5,7-tetrahydroxyflavone", "lutolin", "peanut-hull luteolin (discussed)" ], "type": "Non-peptide", "category": "Longevity & cellular energy", "goals_use_cases": [ "focus", "NAD sparing / CD38 talk", "apigenin stack", "mast-cell / histamine folklore", "inflammation discussion", "brain fog / neuroinflammation talk" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "luteolin", "lutolin", "luteolin cd38", "lutein luteolin", "luteolin apigenin", "nad", "cd38", "histamine", "brain fog", "mast cell", "sleepy" ], "feel_search": [ "nad", "cd38", "histamine", "brain fog", "mast cell", "sleepy" ], "summary": "Luteolin is a plant flavonoid sold as a supplement, discussed for histamine-related symptoms, inflammation and experimental NAD-support ideas.", "search_blob": "luteolin luteolin luteolin flavonoid cd38 luteolin luteolin flavonoid 3',4',5,7-tetrahydroxyflavone lutolin peanut-hull luteolin (discussed) luteolin lutolin luteolin cd38 lutein luteolin luteolin apigenin nad cd38 histamine brain fog mast cell sleepy focus nad sparing / cd38 talk apigenin stack mast-cell / histamine folklore inflammation discussion brain fog / neuroinflammation talk nad cd38 histamine brain fog mast cell sleepy luteolin is a plant flavonoid sold as a supplement, discussed for histamine-related symptoms, inflammation and experimental nad-support ideas. reports include clearer thinking or fewer allergy-like symptoms, no change, tiredness, restless sleep, headache and worse pain. products and co-ingredients differ; early improvement does not establish later tolerability. luteolin is a plant flavonoid discussed for mast-cell symptoms and brain fog. reports include relief, no change, tiredness, restless sleep and other adverse reactions. older notes list 100\u2013200 mg in stacks, but products and exposure differ. luteolin is distinct from lutein. longevity & cellular energy non-peptide systemic oral plant flavonoid; formulation and co-ingredients vary across reports. systemic whole-body circulating", "legal_class": null }, { "id": 280, "slug": "ecnoglutide", "name": "Ecnoglutide", "aliases": [ "XW003", "XW-003", "Sciwind ecnoglutide", "cAMP-biased GLP-1", "ecnoglutide injection" ], "type": "Peptide", "category": "Metabolic / GLP-1 class", "goals_use_cases": [ "fat loss", "appetite control", "type 2 diabetes (trial/label in China)", "GLP-1 pipeline talk", "biased-agonist folklore" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "ecnoglutide", "xw003", "xw-003", "sciwind", "ecnoglutide glp", "biased glp-1", "appetite", "nausea", "food noise", "glp", "china glp-1" ], "feel_search": [ "appetite", "nausea", "food noise", "glp", "china glp-1" ], "summary": "Ecnoglutide (XW003) is a GLP-1 peptide injection developed for type 2 diabetes and weight management.", "search_blob": "ecnoglutide ecnoglutide xw003 xw-003 sciwind ecnoglutide camp-biased glp-1 ecnoglutide injection ecnoglutide xw003 xw-003 sciwind ecnoglutide glp biased glp-1 appetite nausea food noise glp china glp-1 fat loss appetite control type 2 diabetes (trial/label in china) glp-1 pipeline talk biased-agonist folklore appetite nausea food noise glp china glp-1 ecnoglutide (xw003) is a glp-1 peptide injection developed for type 2 diabetes and weight management. the inspected community thread discusses trial news, competition and price. it supplies no firsthand ecnoglutide response or everyday timeline. ecnoglutide, or xw003, is a glp-1 peptide injection studied for type 2 diabetes and weight management. saved community discussion concerns trial news and expectations. the 2.4 mg weekly obesity arm is a study amount. no verified use diary in the inspected discussions establishes a typical appetite response or combination. metabolic / glp-1 class peptide systemic a weekly subcutaneous glp-1 formulation with systemic effects on appetite and glucose regulation. systemic whole-body circulating", "legal_class": null }, { "id": 281, "slug": "trevogrumab", "name": "Trevogrumab", "aliases": [ "REGN1033", "anti-GDF8 antibody", "anti-myostatin mAb COURAGE", "trevogrumab Regeneron" ], "type": "Non-peptide", "category": "Growth factors / muscle", "goals_use_cases": [ "GLP muscle-spare talk", "myostatin inhibition", "lean-mass preservation", "obesity combination trials" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "trevogrumab", "regn1033", "courage antibody", "anti gdf8", "courage trial", "glp muscle spare antibody", "anti myostatin", "regeneron gdf8" ], "feel_search": [ "courage trial", "glp muscle spare antibody", "anti myostatin", "regeneron gdf8" ], "summary": "Trevogrumab is an investigational antibody against myostatin, studied with weight-loss drugs to limit loss of lean mass.", "search_blob": "trevogrumab trevogrumab regn1033 anti-gdf8 antibody anti-myostatin mab courage trevogrumab regeneron trevogrumab regn1033 courage antibody anti gdf8 courage trial glp muscle spare antibody anti myostatin regeneron gdf8 glp muscle-spare talk myostatin inhibition lean-mass preservation obesity combination trials courage trial glp muscle spare antibody anti myostatin regeneron gdf8 trevogrumab is an investigational antibody against myostatin, studied with weight-loss drugs to limit loss of lean mass. the public combination-trial report describes tolerability and body-composition results, without establishing a distinctive everyday sensation. trevogrumab is an investigational myostatin antibody studied for lean-mass preservation during weight loss. one unverified bodybuilding account reports perceived gains alongside repeated severe pain. trial milligrams with semaglutide. not flgr. not a research-vial chart. growth factors / muscle non-peptide systemic systemic anti-myostatin antibody used in obesity combination trials. systemic whole-body circulating", "legal_class": null }, { "id": 282, "slug": "garetosmab", "name": "Garetosmab", "aliases": [ "Pasatru", "REGN2477", "anti-activin A antibody", "garetosmab-grts", "COURAGE triplet antibody" ], "type": "Non-peptide", "category": "Growth factors / muscle", "goals_use_cases": [ "activin A blockade", "GLP muscle-spare talk", "FOP / heterotopic bone talk", "COURAGE triplet" ], "delivery_methods": [ "IV" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "garetosmab", "pasatru", "regn2477", "anti activin a", "courage triplet", "activin antibody", "fop antibody" ], "feel_search": [ "pasatru", "courage triplet", "activin antibody", "fop antibody" ], "summary": "Garetosmab is an activin-A-blocking antibody; biohackers discuss its role in experimental combinations intended to preserve muscle during weight loss.", "search_blob": "garetosmab garetosmab pasatru regn2477 anti-activin a antibody garetosmab-grts courage triplet antibody garetosmab pasatru regn2477 anti activin a courage triplet activin antibody fop antibody activin a blockade glp muscle-spare talk fop / heterotopic bone talk courage triplet pasatru courage triplet activin antibody fop antibody garetosmab is an activin-a-blocking antibody; biohackers discuss its role in experimental combinations intended to preserve muscle during weight loss. there is no established everyday feel profile in the reviewed sources. trial body-composition changes are measurements, and adverse events or stopping treatment are separate outcomes. garetosmab blocks activin a. discussion centers on combination-trial findings; verified physique-use experiences were not established. comparisons with flgr concern different products. trial amounts and disease treatment do not establish a bodybuilding regimen. growth factors / muscle non-peptide systemic systemic anti-activin a antibody \u2014 courage triplet and a separate fop approval. systemic whole-body circulating", "legal_class": null }, { "id": 283, "slug": "rusfertide", "name": "Rusfertide", "aliases": [ "MIMRYLO", "PTG-300", "hepcidin mimetic", "rusfertide PV" ], "type": "Peptide", "category": "Hormone modulators", "goals_use_cases": [ "muscle", "polycythemia vera talk", "approved peptide medicine", "polycythemia vera / erythrocytosis talk", "hepcidin / iron regulation", "approved peptide medicine vs gray GLP" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "rusfertide", "mimrylo", "ptg-300", "hepcidin peptide", "hepcidin", "polycythemia peptide", "approved peptide" ], "feel_search": [ "mimrylo", "hepcidin", "polycythemia peptide", "approved peptide" ], "summary": "Rusfertide (PTG-300) mimics the iron-regulating hormone hepcidin; it is developed for polycythemia vera, a disorder with too many red blood cells.", "search_blob": "rusfertide rusfertide mimrylo ptg-300 hepcidin mimetic rusfertide pv rusfertide mimrylo ptg-300 hepcidin peptide hepcidin polycythemia peptide approved peptide muscle polycythemia vera talk approved peptide medicine polycythemia vera / erythrocytosis talk hepcidin / iron regulation approved peptide medicine vs gray glp mimrylo hepcidin polycythemia peptide approved peptide rusfertide (ptg-300) mimics the iron-regulating hormone hepcidin; it is developed for polycythemia vera, a disorder with too many red blood cells. the reviewed evidence describes blood-count control and reduced treatment burden in polycythemia vera, rather than a general energy or gym effect. rusfertide is an iron-regulating peptide discussed for polycythemia vera. patients seek fewer blood removals and better daily function; fatigue does not improve in every account. the saved mimrylo record concerns disease-specific medical care. it does not establish a weight-loss use or authenticate an unrelated product. hormone modulators peptide systemic a systemic iron-regulating peptide used in the polycythemia vera treatment context. systemic whole-body circulating", "legal_class": null }, { "id": 284, "slug": "ace-083", "name": "ACE-083", "aliases": [ "ACE083", "local follistatin ligand trap", "Acceleron ACE-083" ], "type": "Peptide", "category": "Growth factors / muscle", "goals_use_cases": [ "local muscle volume", "follistatin-class comparison", "myostatin / activin trap talk" ], "delivery_methods": [ "intramuscular" ], "discussion_popularity": "Emerging", "reach": "Local", "misspellings_search_terms": [ "ace-083", "ace083", "local follistatin trap", "ace 083", "local follistatin", "size without function", "fshd peptide" ], "feel_search": [ "ace 083", "local follistatin", "size without function", "fshd peptide" ], "summary": "ACE-083 is a modified follistatin protein studied by injection into selected muscles to increase local muscle volume.", "search_blob": "ace-083 ace-083 ace083 local follistatin ligand trap acceleron ace-083 ace-083 ace083 local follistatin trap ace 083 local follistatin size without function fshd peptide local muscle volume follistatin-class comparison myostatin / activin trap talk ace 083 local follistatin size without function fshd peptide ace-083 is a modified follistatin protein studied by injection into selected muscles to increase local muscle volume. unverified product accounts include an authenticity concern, overnight biceps soreness and a separate severe acute reaction. none supplies a measured muscle-growth result or dependable benefit timeline. ace-083 is an experimental follistatin-based protein studied for local muscle growth. disease-trial volume gains did not consistently improve function; outside-product reports lack measured growth outcomes. both disease programs were discontinued. online accounts include uncertain product identity, soreness and a severe reaction, without a validated bodybuilding regimen. growth factors / muscle peptide local follistatin-based protein designed for local activity in the injected muscle; outside products are not authenticated as the trial formulation. local site pin topical", "legal_class": null }, { "id": 285, "slug": "mid-35", "name": "MID-35", "aliases": [ "MID35", "myostatin inhibitory D-peptide-35", "MIPE-1686 successor", "retro-inverso myostatin peptide" ], "type": "Peptide", "category": "Growth factors / muscle", "goals_use_cases": [ "muscle", "local myostatin blockade", "comparison to FLGR-242", "research IM peptide" ], "delivery_methods": [ "intramuscular" ], "discussion_popularity": "Emerging", "reach": "Local", "misspellings_search_terms": [ "mid-35", "mid35", "mid 35 peptide", "d-peptide myostatin", "mid 35", "flgr vs mid", "local myostatin peptide" ], "feel_search": [ "mid 35", "d-peptide myostatin", "flgr vs mid", "local myostatin peptide" ], "summary": "MID-35 is an experimental 16-amino-acid D-peptide studied as a myostatin inhibitor for muscle growth in mice.", "search_blob": "mid-35 mid-35 mid35 myostatin inhibitory d-peptide-35 mipe-1686 successor retro-inverso myostatin peptide mid-35 mid35 mid 35 peptide d-peptide myostatin mid 35 flgr vs mid local myostatin peptide muscle local myostatin blockade comparison to flgr-242 research im peptide mid 35 d-peptide myostatin flgr vs mid local myostatin peptide mid-35 is an experimental 16-amino-acid d-peptide studied as a myostatin inhibitor for muscle growth in mice. no human experience report was found in the reviewed sources. mouse muscle measurements do not establish a human feeling, onset or duration. mid-35 is an experimental myostatin-inhibiting peptide studied in mouse muscle. the inspected sources establish no firsthand human benefit or typical feeling. mouse administration and related-product schedules do not establish a human amount, route or repeat calendar. growth factors / muscle peptide local local delivery in mouse muscle experiments; human distribution and effectiveness are not established here. local site pin topical", "legal_class": null }, { "id": 286, "slug": "ashwagandha", "name": "Ashwagandha", "aliases": [ "Withania somnifera", "KSM-66", "Sensoril", "Shoden", "Indian ginseng (marketplace label)", "winter cherry", "withanolides", "ashwaganda (common misspelling)" ], "type": "Non-peptide", "category": "Herbals in hormone discourse", "goals_use_cases": [ "sleep", "stress", "testosterone support (discussed)", "stress / cortisol (discussed)", "anxiety / calm (discussed)", "recovery", "libido (discussed)", "not a SARM" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "ashwaganda", "ashwaghanda", "ashwagandha ksm66", "withania", "sensoril ashwagandha", "ksm-66", "indian ginseng", "calm", "wired at night", "anhedonia", "flat affect", "cortisol", "natural test", "ksm-66 vs sensoril", "liver", "can't sleep", "not a sarm" ], "feel_search": [ "calm", "wired at night", "anhedonia", "flat affect", "cortisol", "natural test", "ksm-66 vs sensoril", "liver", "can't sleep", "not a sarm" ], "summary": "Ashwagandha is the herb Withania somnifera, sold as root or root-and-leaf extracts for stress, sleep and relaxation.", "search_blob": "ashwagandha ashwagandha withania somnifera ksm-66 sensoril shoden indian ginseng (marketplace label) winter cherry withanolides ashwaganda (common misspelling) ashwaganda ashwaghanda ashwagandha ksm66 withania sensoril ashwagandha ksm-66 indian ginseng calm wired at night anhedonia flat affect cortisol natural test ksm-66 vs sensoril liver can't sleep not a sarm sleep stress testosterone support (discussed) stress / cortisol (discussed) anxiety / calm (discussed) recovery libido (discussed) not a sarm calm wired at night anhedonia flat affect cortisol natural test ksm-66 vs sensoril liver can't sleep not a sarm ashwagandha is the herb withania somnifera, sold as root or root-and-leaf extracts for stress, sleep and relaxation. the inspected thread includes calmer mood and early energy alongside anger or depressed mood. extracts and co-use differ, so one response is not predictable. ashwagandha is the herb withania somnifera, discussed for stress and sleep. some describe less rumination; others notice no benefit or unwanted changes in mood and energy. root and root-and-leaf extracts differ. emotional blunting, liver-injury reports, thyroid concerns and medication interactions remain relevant. herbals in hormone discourse non-peptide systemic systemic oral root (or root-and-leaf) extract \u2014 sleep, stress, and natural-t talk, not a sarm. systemic whole-body circulating", "legal_class": null }, { "id": 287, "slug": "lions-mane", "name": "Lion's mane", "aliases": [ "Hericium erinaceus", "Yamabushitake", "mushroom coffee lion's mane", "Hericium", "lion's mane mushroom", "lions mane" ], "type": "Non-peptide", "category": "Cognitive research compounds", "goals_use_cases": [ "cognition", "NGF / nerve-growth talk", "focus / word-finding (discussed)", "mood (discussed)", "mushroom coffee stacks", "nerve repair lore (discussed)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "lions mane", "lion mane", "lionsmane", "hericium erinaceus", "yamabushitake", "hericenone", "erinacine", "mushroom coffee", "hericenones", "erinacines", "brain fog", "word finding", "ngf itch", "focus", "nerve growth", "fruiting body vs mycelium" ], "feel_search": [ "brain fog", "word finding", "ngf itch", "mushroom coffee", "focus", "nerve growth", "yamabushitake", "fruiting body vs mycelium" ], "summary": "Lion\u2019s mane is the mushroom Hericium erinaceus, sold as powders and extracts for cognition; fruiting-body and mycelium products are not equivalent.", "search_blob": "lion's mane lions-mane hericium erinaceus yamabushitake mushroom coffee lion's mane hericium lion's mane mushroom lions mane lions mane lion mane lionsmane hericium erinaceus yamabushitake hericenone erinacine mushroom coffee hericenones erinacines brain fog word finding ngf itch focus nerve growth fruiting body vs mycelium cognition ngf / nerve-growth talk focus / word-finding (discussed) mood (discussed) mushroom coffee stacks nerve repair lore (discussed) brain fog word finding ngf itch mushroom coffee focus nerve growth yamabushitake fruiting body vs mycelium lion\u2019s mane is the mushroom hericium erinaceus, sold as powders and extracts for cognition; fruiting-body and mycelium products are not equivalent. some report clearer recall or calm, while others remain unchanged or describe poorer recall, sleep disruption, lethargy or anxiety. gut symptoms and itching also appear, without a dependable frequency or sequence. lion's mane is an edible mushroom discussed for cognition. reports include clearer recall, no benefit, poorer recall, lethargy, anxiety and disrupted sleep across different products. mori's mci trial used about 3 g/day tablet mass containing 96% mushroom powder. coffee blends, extracts and enriched mycelia are different preparations. cognitive research compounds non-peptide systemic systemic oral mushroom \u2014 ngf/cognition talk and coffee packets, not a nasal peptide. systemic whole-body circulating", "legal_class": null }, { "id": 288, "slug": "omega-3", "name": "Omega-3 (EPA/DHA)", "aliases": [ "fish oil", "EPA/DHA", "icosapent ethyl talk", "EPA", "DHA", "icosapent ethyl", "Vascepa-class EPA", "krill oil (adjacent)", "algae oil", "omega 3", "n-3 PUFA" ], "type": "Non-peptide", "category": "Performance staples (biohacking overlap)", "goals_use_cases": [ "triglycerides", "recovery", "inflammation talk", "mood (discussed)", "heart-risk discussion", "omega-3 index", "rancid oil watch-for" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "omega3", "omega 3", "fishoil", "fish oil", "epa dha", "vascepa", "icosapent", "krill oil", "algae oil", "rancid fish oil", "fish burp", "rancid", "triglycerides", "omega-3 index", "atrial fibrillation", "epa vs dha", "ifos", "krill" ], "feel_search": [ "fish burp", "rancid", "triglycerides", "omega-3 index", "atrial fibrillation", "epa vs dha", "ifos", "vascepa", "krill" ], "summary": "Omega-3 products supply EPA and DHA from fish, algae or krill; people seek lipid, mood or joint benefits, but formulations differ.", "search_blob": "omega-3 (epa/dha) omega-3 fish oil epa/dha icosapent ethyl talk epa dha icosapent ethyl vascepa-class epa krill oil (adjacent) algae oil omega 3 n-3 pufa omega3 omega 3 fishoil fish oil epa dha vascepa icosapent krill oil algae oil rancid fish oil fish burp rancid triglycerides omega-3 index atrial fibrillation epa vs dha ifos krill triglycerides recovery inflammation talk mood (discussed) heart-risk discussion omega-3 index rancid oil watch-for fish burp rancid triglycerides omega-3 index atrial fibrillation epa vs dha ifos vascepa krill omega-3 products supply epa and dha from fish, algae or krill; people seek lipid, mood or joint benefits, but formulations differ. some people describe calmer mood or easier movement; others notice no benefit, gut discomfort, worse mood or disrupted sleep. no reliable immediate sensation or hours-per-capsule benefit window emerges. omega-3 products supply epa and dha fats. reports include mood or joint benefit, no change and gut or sleep problems; prescription cardiovascular evidence belongs to specific formulations and populations. component amounts matter: 4 g prescription icosapent ethyl is not interchangeable with a supplement labeled 180/120 for epa/dha. performance staples (biohacking overlap) non-peptide systemic oral epa/dha products with systemic exposure; lipid measurements, subjective effects and tolerability are different outcomes. systemic whole-body circulating", "legal_class": null }, { "id": 289, "slug": "hmb", "name": "HMB", "aliases": [ "beta-hydroxy-beta-methylbutyrate", "Ca-HMB", "HMB-FA", "\u03b2-hydroxy \u03b2-methylbutyrate", "BetaTOR-class free acid", "hydroxymethylbutyrate", "leucine metabolite HMB" ], "type": "Non-peptide", "category": "Performance staples (biohacking overlap)", "goals_use_cases": [ "muscle spare / anti-catabolic talk", "GLP-adjacent lean-mass talk", "recovery", "sarcopenia-adjacent", "not a myostatin antibody" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "hmb", "h.m.b", "beta hydroxy beta methylbutyrate", "hydroxymethylbutyrate", "ca-hmb", "hmb-fa", "leucine metabolite", "glp hmb", "muscle spare", "glp muscle", "anti catabolic", "creatine hmb", "not bimagrumab", "cut", "sarcopenia" ], "feel_search": [ "muscle spare", "glp muscle", "anti catabolic", "creatine hmb", "not bimagrumab", "cut", "sarcopenia", "hmb-fa" ], "summary": "HMB is a metabolite of the amino acid leucine, sold as calcium HMB or free-acid HMB for muscle maintenance and recovery.", "search_blob": "hmb hmb beta-hydroxy-beta-methylbutyrate ca-hmb hmb-fa \u03b2-hydroxy \u03b2-methylbutyrate betator-class free acid hydroxymethylbutyrate leucine metabolite hmb hmb h.m.b beta hydroxy beta methylbutyrate hydroxymethylbutyrate ca-hmb hmb-fa leucine metabolite glp hmb muscle spare glp muscle anti catabolic creatine hmb not bimagrumab cut sarcopenia muscle spare / anti-catabolic talk glp-adjacent lean-mass talk recovery sarcopenia-adjacent not a myostatin antibody muscle spare glp muscle anti catabolic creatine hmb not bimagrumab cut sarcopenia hmb-fa hmb is a metabolite of the amino acid leucine, sold as calcium hmb or free-acid hmb for muscle maintenance and recovery. some users describe less soreness or retained strength; others notice no difference after months. older accounts describe little acute buzz or pump, and stomach discomfort is reported. hmb is an oral leucine metabolite discussed for recovery and retaining strength during weight loss. some report less soreness; others notice no difference. calcium and free-acid products differ. the often-cited 3 g/day is a study amount, and concurrent creatine, protein and training complicate personal reports. performance staples (biohacking overlap) non-peptide systemic systemic oral leucine metabolite \u2014 muscle-spare talk on cuts and glp threads, not a myostatin antibody. systemic whole-body circulating", "legal_class": null }, { "id": 290, "slug": "testosterone", "name": "Testosterone", "aliases": [ "TRT", "test cypionate", "testosterone cypionate", "test enanthate", "testosterone enanthate", "testosterone gel", "AndroGel-class talk", "testosterone replacement", "test E", "test C" ], "type": "Non-peptide", "category": "Hormones in performance discourse", "goals_use_cases": [ "libido", "energy", "muscle", "recovery", "mood (discussed)", "TRT" ], "delivery_methods": [ "intramuscular", "subcutaneous", "topical" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "test cyp", "test e", "trt", "testosterone cyp", "androgel", "low t", "pin", "hematocrit", "libido", "cruise" ], "feel_search": [ "low t", "trt", "pin", "hematocrit", "libido", "cruise" ], "summary": "Testosterone is an androgen hormone used in replacement therapy and bodybuilding; cypionate and enanthate are commonly discussed ester forms.", "search_blob": "testosterone testosterone trt test cypionate testosterone cypionate test enanthate testosterone enanthate testosterone gel androgel-class talk testosterone replacement test e test c test cyp test e trt testosterone cyp androgel low t pin hematocrit libido cruise libido energy muscle recovery mood (discussed) trt low t trt pin hematocrit libido cruise testosterone is an androgen hormone used in replacement therapy and bodybuilding; cypionate and enanthate are commonly discussed ester forms. accounts include improved energy, motivation or sex drive, no improvement and worse libido. a substantial hair-thinning report involved higher exposures and other steroids. testosterone is an androgen hormone discussed for replacement, libido, energy and bodybuilding. reports include improvement, no change and worse symptoms; preparations and exposure differ. u.s. schedule iii. fertility suppression, blood pressure, hematocrit and mood or skin changes matter; a higher testosterone result does not guarantee symptom improvement. hormones in performance discourse non-peptide systemic testosterone discussions include replacement and higher-exposure bodybuilding, with different preparations, goals and product-identity uncertainty. [community] u.s. schedule iii iii systemic whole-body circulating", "legal_class": { "schedule": "III", "label": "U.S. Schedule III" } }, { "id": 295, "slug": "modafinil", "name": "Modafinil", "aliases": [ "Provigil", "moda", "smart drug modafinil", "wakefulness agent" ], "type": "Non-peptide", "category": "Wakefulness agents in productivity discourse", "goals_use_cases": [ "focus (discussed)", "wakefulness", "productivity (discussed)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "provigil", "nuvigil", "armodafinil", "modalert", "moda", "Nuvigil", "clean stim", "forgot to eat", "insomnia", "focus", "not adderall" ], "feel_search": [ "moda", "clean stim", "forgot to eat", "insomnia", "focus", "not adderall" ], "summary": "Modafinil is a prescription wakefulness medicine; people also discuss it for staying alert through work, study or shift schedules.", "search_blob": "modafinil modafinil provigil moda smart drug modafinil wakefulness agent provigil nuvigil armodafinil modalert moda nuvigil clean stim forgot to eat insomnia focus not adderall focus (discussed) wakefulness productivity (discussed) moda clean stim forgot to eat insomnia focus not adderall modafinil is a prescription wakefulness medicine; people also discuss it for staying alert through work, study or shift schedules. some describe steady alertness or easier sustained attention; others feel little. appetite loss and difficulty sleeping can outlast the useful work period. modafinil is an oral prescription wakefulness medicine. some report steadier attention; others remain exhausted, think less clearly or develop insomnia despite morning use. u.s. schedule iv; sharing a saved plan can reveal its entry. sleep disruption, serious rash and medicine interactions are separate concerns. wakefulness agents in productivity discourse non-peptide systemic oral modafinil amounts of 100\u2013200 mg appear in workday reports. related armodafinil has a different composition and exposure profile; the products are not interchangeable. [community] u.s. schedule iv iv systemic whole-body circulating", "legal_class": { "schedule": "IV", "label": "U.S. Schedule IV" } }, { "id": 296, "slug": "nicotine-pouches", "name": "Nicotine pouches", "aliases": [ "Zyn", "nicotine pouch", "oral nicotine", "nicotine gum (adjacent)", "On! pouches", "Velo pouches" ], "type": "Non-peptide", "category": "Stimulants in focus discourse", "goals_use_cases": [ "focus (discussed)", "appetite (discussed)", "alertness" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "zyn", "nicotine pouch", "velo", "on pouches", "nic pouches", "pouch", "buzz", "appetite", "addiction", "focus" ], "feel_search": [ "zyn", "pouch", "buzz", "appetite", "addiction", "focus" ], "summary": "Nicotine pouches release nicotine through the mouth; people use them for a short buzz or focus, and repeated use can lead to dependence.", "search_blob": "nicotine pouches nicotine-pouches zyn nicotine pouch oral nicotine nicotine gum (adjacent) on! pouches velo pouches zyn nicotine pouch velo on pouches nic pouches pouch buzz appetite addiction focus focus (discussed) appetite (discussed) alertness zyn pouch buzz appetite addiction focus nicotine pouches release nicotine through the mouth; people use them for a short buzz or focus, and repeated use can lead to dependence. people describe a brief buzz, focus or mental relief, but nausea and irritation can occur. with repeated use, the noticeable relief may coexist with cravings or irritability between pouches. nicotine pouches release nicotine through the mouth lining. reports include a brief buzz or concentration, no focus benefit, nausea and dependence. pouch strength, frequency and absorbed nicotine differ. staying at a lower strength does not prevent dependence; sharing a plan that lists use can reveal the habit. stimulants in focus discourse non-peptide systemic nicotine is absorbed through the mouth lining from a pouch between lip and gum; the effects are systemic. age-restricted / locally regulated listed systemic whole-body circulating", "legal_class": { "schedule": "listed", "label": "Age-restricted / locally regulated" } }, { "id": 298, "slug": "mesterolone", "name": "Mesterolone", "aliases": [ "Proviron", "Provironum", "Androviron", "1-methyl-DHT", "1\u03b1-methyl DHT", "oral DHT derivative" ], "type": "Non-peptide", "category": "Hormones in performance discourse", "goals_use_cases": [ "libido", "mood (discussed)", "SHBG (discussed)", "hardening (discussed)", "TRT adjunct (discussed)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "proviron", "provironum", "mesterolon", "masterolone", "1-methyl dht", "shbg", "dry", "libido", "hardening", "dht" ], "feel_search": [ "proviron", "shbg", "dry", "libido", "hardening", "dht" ], "summary": "Mesterolone (Proviron) is an oral DHT-derived androgen, discussed as a TRT or steroid-cycle add-on for libido, mood and a drier appearance.", "search_blob": "mesterolone mesterolone proviron provironum androviron 1-methyl-dht 1\u03b1-methyl dht oral dht derivative proviron provironum mesterolon masterolone 1-methyl dht shbg dry libido hardening dht libido mood (discussed) shbg (discussed) hardening (discussed) trt adjunct (discussed) proviron shbg dry libido hardening dht mesterolone (proviron) is an oral dht-derived androgen, discussed as a trt or steroid-cycle add-on for libido, mood and a drier appearance. mesterolone is an oral dht-derived androgen discussed for libido, mood and a drier appearance alongside testosterone. accounts include benefit, no change, fading benefit and feeling worse. schedule iii. hair, prostate, counterfeits, and sharing a plan that lists it are the watch-for. hormones in performance discourse non-peptide systemic mesterolone is an oral dht-derived androgen discussed alongside testosterone for libido, mood and appearance. [community] u.s. schedule iii iii systemic whole-body circulating", "legal_class": { "schedule": "III", "label": "U.S. Schedule III" } }, { "id": 300, "slug": "trenbolone", "name": "Trenbolone", "aliases": [ "tren", "tren ace", "trenbolone acetate", "tren enanthate", "tren e", "Parabolan-class talk" ], "type": "Non-peptide", "category": "Hormones in performance discourse", "goals_use_cases": [ "muscle growth", "hardening (discussed)", "fat loss (discussed)", "strength", "night sweats (watch-for)" ], "delivery_methods": [ "intramuscular", "subcutaneous" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "tren a", "tren e", "parabolan", "trenbolone ace", "tren", "night sweats", "tren cough", "insomnia", "blast" ], "feel_search": [ "tren", "night sweats", "tren cough", "insomnia", "blast" ], "summary": "Trenbolone is an anabolic-androgenic steroid discussed in bodybuilding, usually as acetate or enanthate esters.", "search_blob": "trenbolone trenbolone tren tren ace trenbolone acetate tren enanthate tren e parabolan-class talk tren a tren e parabolan trenbolone ace tren night sweats tren cough insomnia blast muscle growth hardening (discussed) fat loss (discussed) strength night sweats (watch-for) tren night sweats tren cough insomnia blast trenbolone is an anabolic-androgenic steroid discussed in bodybuilding, usually as acetate or enanthate esters. accounts describe strength and drive alongside sweating, disturbed sleep, anxiety and worse exercise tolerance; some reported few mental changes. trenbolone is an anabolic-androgenic steroid discussed for strength and physique changes. reports include little benefit as well as insomnia, sweating, mood changes and reduced exercise tolerance. schedule iii. favorable gym results can coexist with sleep, mood, cardiovascular or injection-related problems; hormone explanations in forums are not confirmed diagnoses. hormones in performance discourse non-peptide systemic injectable 19-nor androgen in enhanced-athlete talk \u2014 acetate and enanthate, not a sarm and not testosterone. u.s. schedule iii iii systemic whole-body circulating", "legal_class": { "schedule": "III", "label": "U.S. Schedule III" } }, { "id": 301, "slug": "nandrolone", "name": "Nandrolone", "aliases": [ "Deca", "Deca-Durabolin", "nandrolone decanoate", "NPP", "nandrolone phenylpropionate", "19-nor" ], "type": "Non-peptide", "category": "Hormones in performance discourse", "goals_use_cases": [ "joint comfort (discussed)", "muscle growth", "recovery", "strength" ], "delivery_methods": [ "intramuscular" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "deca durabolin", "nandrolone deca", "phenylpropionate", "deca", "npp", "joints", "deca dick", "19-nor" ], "feel_search": [ "deca", "npp", "joints", "deca dick", "19-nor" ], "summary": "Nandrolone is an anabolic steroid used as Deca or NPP injections; people discuss muscle gain and joint comfort, with different ester durations.", "search_blob": "nandrolone nandrolone deca deca-durabolin nandrolone decanoate npp nandrolone phenylpropionate 19-nor deca durabolin nandrolone deca phenylpropionate deca npp joints deca dick 19-nor joint comfort (discussed) muscle growth recovery strength deca npp joints deca dick 19-nor nandrolone is an anabolic steroid used as deca or npp injections; people discuss muscle gain and joint comfort, with different ester durations. users describe fuller muscles, strength or easier joints, but libido, mood and water retention vary. some report intrusive rumination or anxiety that makes the tradeoff unacceptable. nandrolone is an injectable anabolic steroid discussed for muscle, strength and joint comfort. reports also include no worthwhile benefit, sexual dysfunction and difficult mood changes. deca and npp have different release forms. symptoms do not establish high prolactin, and feeling well does not rule out adverse blood-pressure or cholesterol changes. hormones in performance discourse non-peptide systemic a systemic injectable anabolic steroid. decanoate (deca) and phenylpropionate (npp) are different ester formulations with different release timing; nandrolone is not testosterone. u.s. schedule iii iii systemic whole-body circulating", "legal_class": { "schedule": "III", "label": "U.S. Schedule III" } }, { "id": 302, "slug": "oxandrolone", "name": "Oxandrolone", "aliases": [ "Anavar", "Var", "oxandrolone 10 mg", "oxandrolone 25 mg" ], "type": "Non-peptide", "category": "Hormones in performance discourse", "goals_use_cases": [ "hardening (discussed)", "strength", "fat loss (discussed)", "women\u2019s oral AAS (discussed)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "anavar 10", "oxandrin", "anavar 25", "anavar", "var", "dry", "cut", "women" ], "feel_search": [ "anavar", "var", "dry", "cut", "women" ], "summary": "Oxandrolone (Anavar) is an oral anabolic steroid discussed for strength and a leaner appearance; it is not a SARM.", "search_blob": "oxandrolone oxandrolone anavar var oxandrolone 10 mg oxandrolone 25 mg anavar 10 oxandrin anavar 25 anavar var dry cut women hardening (discussed) strength fat loss (discussed) women\u2019s oral aas (discussed) anavar var dry cut women oxandrolone (anavar) is an oral anabolic steroid discussed for strength and a leaner appearance; it is not a sarm. users describe stronger lifts and pumps, sometimes with appetite loss or painful back pumps. feeling good can coexist with unfavorable lab changes; experiences vary. oxandrolone is an oral anabolic steroid discussed for strength and a leaner appearance. reports include useful workouts, little benefit and adverse effects; appearance changes do not prove fat loss. lipid and liver effects, hormone suppression and potentially persistent masculinizing changes matter even when workouts feel good. hormones in performance discourse non-peptide systemic oxandrolone, often called anavar, is an oral dht-related anabolic androgenic steroid discussed for strength and a leaner appearance. men's and women's reports have different amounts, co-use and adverse effects. u.s. schedule iii iii systemic whole-body circulating", "legal_class": { "schedule": "III", "label": "U.S. Schedule III" } }, { "id": 303, "slug": "stanozolol", "name": "Stanozolol", "aliases": [ "Winstrol", "Winny", "stanozolol oral", "stanozolol injectable", "Winstrol Depot-class talk" ], "type": "Non-peptide", "category": "Hormones in performance discourse", "goals_use_cases": [ "hardening (discussed)", "strength", "cut (discussed)", "vascularity (discussed)" ], "delivery_methods": [ "oral", "intramuscular" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "winstrol depot", "stanozolol winny", "winstrol", "winny", "dry joints", "vascular" ], "feel_search": [ "winstrol", "winny", "dry joints", "vascular" ], "summary": "Stanozolol, or Winstrol, is an anabolic steroid discussed for strength and a drier physique, sold in oral and injectable forms.", "search_blob": "stanozolol stanozolol winstrol winny stanozolol oral stanozolol injectable winstrol depot-class talk winstrol depot stanozolol winny winstrol winny dry joints vascular hardening (discussed) strength cut (discussed) vascularity (discussed) winstrol winny dry joints vascular stanozolol, or winstrol, is an anabolic steroid discussed for strength and a drier physique, sold in oral and injectable forms. users describe a drier, more vascular look and stronger gym drive, with sharply mixed reports of joint pain and irritability. stanozolol is an anabolic steroid discussed in oral and injectable forms for strength and a more defined appearance. reports range from striking cosmetic changes to little benefit and disruptive joint symptoms. schedule iii. joint pain, liver and lipid effects, hormonal changes and hair shedding matter even when gym results are favorable; injection does not establish liver safety. hormones in performance discourse non-peptide systemic a systemic dht-derived anabolic-androgenic steroid discussed in oral and injectable forms for strength and a more defined appearance. u.s. schedule iii iii systemic whole-body circulating", "legal_class": { "schedule": "III", "label": "U.S. Schedule III" } }, { "id": 304, "slug": "boldenone", "name": "Boldenone", "aliases": [ "Equipoise", "EQ", "boldenone undecylenate", "bold" ], "type": "Non-peptide", "category": "Hormones in performance discourse", "goals_use_cases": [ "appetite (discussed)", "endurance (discussed)", "muscle growth", "red blood cells (watch-for)" ], "delivery_methods": [ "intramuscular" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "boldenone eq", "equipoise 300", "equipoise", "eq", "appetite", "hematocrit" ], "feel_search": [ "equipoise", "eq", "appetite", "hematocrit" ], "summary": "Boldenone undecylenate (Equipoise/EQ) is a long-acting injectable anabolic steroid of veterinary origin, discussed for appetite and muscle gain.", "search_blob": "boldenone boldenone equipoise eq boldenone undecylenate bold boldenone eq equipoise 300 equipoise eq appetite hematocrit appetite (discussed) endurance (discussed) muscle growth red blood cells (watch-for) equipoise eq appetite hematocrit boldenone undecylenate (equipoise/eq) is a long-acting injectable anabolic steroid of veterinary origin, discussed for appetite and muscle gain. a forum user describes intense hunger alongside apathy, depressed mood and daytime sleepiness. testosterone co-use and self-interpreted estradiol changes complicate the account. boldenone is an injectable anabolic steroid discussed for appetite, muscle and endurance. reports include hunger and fullness, but also reduced appetite, little benefit and unwanted mood changes. the long-release undecylenate form differs from cypionate and acetate. blood counts, pressure, suppression and symptoms after stopping remain concerns. hormones in performance discourse non-peptide systemic a systemic injectable anabolic steroid, usually discussed as the long-release undecylenate ester, equipoise or eq. cypionate and acetate are separate ester forms. u.s. schedule iii iii systemic whole-body circulating", "legal_class": { "schedule": "III", "label": "U.S. Schedule III" } }, { "id": 305, "slug": "drostanolone", "name": "Drostanolone", "aliases": [ "Masteron", "Mast", "drostanolone enanthate", "drostanolone propionate", "Masteron prop" ], "type": "Non-peptide", "category": "Hormones in performance discourse", "goals_use_cases": [ "muscle", "hardening (discussed)", "dry look (discussed)", "DHT sides (watch-for)" ], "delivery_methods": [ "intramuscular" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "masteron enanthate", "masteron prop", "drostanolone mast", "masteron", "mast", "dry", "hard" ], "feel_search": [ "masteron", "mast", "dry", "hard" ], "summary": "Drostanolone (Masteron) is an injectable anabolic steroid sold in propionate or enanthate forms, discussed for strength and a harder physique.", "search_blob": "drostanolone drostanolone masteron mast drostanolone enanthate drostanolone propionate masteron prop masteron enanthate masteron prop drostanolone mast masteron mast dry hard muscle hardening (discussed) dry look (discussed) dht sides (watch-for) masteron mast dry hard drostanolone (masteron) is an injectable anabolic steroid sold in propionate or enanthate forms, discussed for strength and a harder physique. one user describes strength and mood benefits with a flatter look; a long-term user describes a leaner look but severe later hair loss. these are individual accounts. drostanolone is an injectable anabolic steroid discussed for a harder appearance, strength and libido. reports also include little visible change, a flatter look, lost libido and hair loss. u.s. schedule iii. hair, urinary symptoms, blood pressure, cholesterol and mood feature in reports; cosmetic benefit does not establish safety or estrogen control. hormones in performance discourse non-peptide systemic drostanolone, often called masteron, is an injectable dht-derived anabolic steroid discussed for strength, libido and a harder appearance. cosmetic goals do not make its effects local to fat or muscle. u.s. schedule iii iii systemic whole-body circulating", "legal_class": { "schedule": "III", "label": "U.S. Schedule III" } }, { "id": 306, "slug": "methenolone", "name": "Methenolone", "aliases": [ "Primobolan", "Primo", "Primobolan Depot", "methenolone enanthate", "methenolone acetate" ], "type": "Non-peptide", "category": "Hormones in performance discourse", "goals_use_cases": [ "muscle", "quality mass (discussed)", "hardening (discussed)", "expensive mild AAS (discussed)" ], "delivery_methods": [ "intramuscular", "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "primobolan depot", "methenolone primo", "primo", "primobolan", "quality", "fake primo" ], "feel_search": [ "primo", "primobolan", "quality", "fake primo" ], "summary": "Methenolone (Primobolan) is an anabolic steroid available as injectable enanthate or oral acetate, discussed for gradual physique and strength changes.", "search_blob": "methenolone methenolone primobolan primo primobolan depot methenolone enanthate methenolone acetate primobolan depot methenolone primo primo primobolan quality fake primo muscle quality mass (discussed) hardening (discussed) expensive mild aas (discussed) primo primobolan quality fake primo methenolone (primobolan) is an anabolic steroid available as injectable enanthate or oral acetate, discussed for gradual physique and strength changes. changes may be subtle: some describe a harder appearance or better training, while others are unsure. the mixed-cycle account also reports injection pain; sensations do not verify product identity. methenolone is an anabolic steroid discussed as injectable enanthate or oral acetate. some report gradual physique and training changes; others notice little added benefit during mixed cycles. schedule iii. reports include hair shedding, injection pain and hormone or cholesterol changes. neither the mild reputation nor price and bloodwork authenticate a product. hormones in performance discourse non-peptide systemic a systemic dht-derived anabolic-androgenic steroid discussed as injectable enanthate and oral acetate. reports concern physique and strength changes, with uncertain product identity. u.s. schedule iii iii systemic whole-body circulating", "legal_class": { "schedule": "III", "label": "U.S. Schedule III" } }, { "id": 307, "slug": "methandrostenolone", "name": "Methandrostenolone", "aliases": [ "Dianabol", "Dbol", "methandienone", "Dianabol 10 mg" ], "type": "Non-peptide", "category": "Hormones in performance discourse", "goals_use_cases": [ "rapid size (discussed)", "strength", "pumps (discussed)", "water (watch-for)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "dianabol 10", "methandienone", "dbol 30", "dbol", "dianabol", "pumps", "water weight" ], "feel_search": [ "dbol", "dianabol", "pumps", "water weight" ], "summary": "Methandrostenolone (Dianabol or Dbol) is an oral anabolic steroid, discussed for rapid strength, pumps and scale-weight gain that includes water.", "search_blob": "methandrostenolone methandrostenolone dianabol dbol methandienone dianabol 10 mg dianabol 10 methandienone dbol 30 dbol dianabol pumps water weight rapid size (discussed) strength pumps (discussed) water (watch-for) dbol dianabol pumps water weight methandrostenolone (dianabol or dbol) is an oral anabolic steroid, discussed for rapid strength, pumps and scale-weight gain that includes water. methandrostenolone, or dianabol, is an oral anabolic steroid discussed for strength and rapid fullness. accounts include both perceived training benefits and no effect, fatigue or appetite loss. weight gain can include water. liver injury, breast symptoms, blood pressure, cholesterol and hormonal effects remain concerns during and after use. hormones in performance discourse non-peptide systemic a systemic oral anabolic steroid, also called dianabol or dbol. rapid weight and appearance changes can include water as well as other tissue. u.s. schedule iii iii systemic whole-body circulating", "legal_class": { "schedule": "III", "label": "U.S. Schedule III" } }, { "id": 308, "slug": "oxymetholone", "name": "Oxymetholone", "aliases": [ "Anadrol", "Adrol", "Anadrol 50", "oxymetholone 50 mg" ], "type": "Non-peptide", "category": "Hormones in performance discourse", "goals_use_cases": [ "rapid size (discussed)", "appetite (discussed)", "strength", "water (watch-for)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "anadrol 50", "oxymetholone 50", "anadrol", "adrol", "appetite", "water" ], "feel_search": [ "anadrol", "adrol", "appetite", "water" ], "summary": "Oxymetholone (Anadrol) is an oral anabolic steroid discussed for rapid strength and size changes, with variable water and appetite effects.", "search_blob": "oxymetholone oxymetholone anadrol adrol anadrol 50 oxymetholone 50 mg anadrol 50 oxymetholone 50 anadrol adrol appetite water rapid size (discussed) appetite (discussed) strength water (watch-for) anadrol adrol appetite water oxymetholone (anadrol) is an oral anabolic steroid discussed for rapid strength and size changes, with variable water and appetite effects. some feel stronger and fuller quickly; others get headache, nausea, heartburn or poor appetite. a rapid scale change includes water and is not a direct measure of new muscle. oxymetholone is an oral anabolic steroid discussed for strength and fullness. appetite can increase, remain unchanged or fall; reflux and blood-pressure problems can accompany a favorable gym response. u.s. schedule iii. liver, lipid, blood-pressure and hormone effects matter; breast symptoms do not identify their hormone cause, and feeling well does not establish safety. hormones in performance discourse non-peptide systemic oxymetholone, often called anadrol, is an oral anabolic steroid discussed for strength, fullness and rapid scale changes. appetite may increase, remain unchanged or fall sharply. u.s. schedule iii iii systemic whole-body circulating", "legal_class": { "schedule": "III", "label": "U.S. Schedule III" } }, { "id": 309, "slug": "turinabol", "name": "Turinabol", "aliases": [ "Tbol", "chlorodehydromethyltestosterone", "4-chlorodehydromethyltestosterone", "Turinabol 10 mg" ], "type": "Non-peptide", "category": "Hormones in performance discourse", "goals_use_cases": [ "dryer oral size (discussed)", "strength", "slower than Dbol (discussed)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "tbol 10", "chlorodehydromethyltestosterone", "tbol", "turinabol", "dry dbol" ], "feel_search": [ "tbol", "turinabol", "dry dbol" ], "summary": "Turinabol, or Tbol, is chlorodehydromethyltestosterone, an oral anabolic steroid discussed for strength and muscle.", "search_blob": "turinabol turinabol tbol chlorodehydromethyltestosterone 4-chlorodehydromethyltestosterone turinabol 10 mg tbol 10 chlorodehydromethyltestosterone tbol turinabol dry dbol dryer oral size (discussed) strength slower than dbol (discussed) tbol turinabol dry dbol turinabol, or tbol, is chlorodehydromethyltestosterone, an oral anabolic steroid discussed for strength and muscle. some users describe stronger pumps and a drier look; others stopped because of headaches, and one reported lethargy at higher exposure. turinabol is an oral anabolic steroid discussed for strength, stamina and a more defined appearance. some report disappointing gains, painful pumps or headaches that lead them to stop. schedule iii. this 17-aa oral steroid retains liver and hormone risks; reported problems also include cholesterol changes, high blood pressure and severe headaches. hormones in performance discourse non-peptide systemic a systemic oral anabolic-androgenic steroid discussed for strength, training stamina and a more defined appearance. u.s. schedule iii iii systemic whole-body circulating", "legal_class": { "schedule": "III", "label": "U.S. Schedule III" } }, { "id": 310, "slug": "clenbuterol", "name": "Clenbuterol", "aliases": [ "Clen", "clenbuterol 40 mcg", "clen tabs" ], "type": "Non-peptide", "category": "Mitochondrial & metabolic compounds", "goals_use_cases": [ "fat loss (discussed)", "tremor (watch-for)", "heart rate (watch-for)", "cramps (watch-for)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "clenbuterol 40", "clen 40mcg", "clen", "shakes", "cramps", "heart rate", "cut" ], "feel_search": [ "clen", "shakes", "cramps", "heart rate", "cut" ], "summary": "Clenbuterol is a beta-2 agonist bronchodilator discussed off-label for fat loss; it is not an anabolic steroid.", "search_blob": "clenbuterol clenbuterol clen clenbuterol 40 mcg clen tabs clenbuterol 40 clen 40mcg clen shakes cramps heart rate cut fat loss (discussed) tremor (watch-for) heart rate (watch-for) cramps (watch-for) clen shakes cramps heart rate cut clenbuterol is a beta-2 agonist bronchodilator discussed off-label for fat loss; it is not an anabolic steroid. reports range from gym energy with little noticed trouble to shaking, a racing heart and insomnia lasting into the night. co-stimulants and product identity vary. clenbuterol is a beta-2 agonist bronchodilator discussed for fat-loss goals. reports include reduced appetite and perceived training benefits, but also severe shaking, insomnia and heart symptoms. sensation does not measure fat loss or product identity. the saved human study estimated about 35 hours of plasma half-life, separate from how long stimulation feels present. mitochondrial & metabolic compounds non-peptide systemic a systemic beta-2 agonist that relaxes airways, discussed orally in bodybuilding cuts. it is distinct from anabolic steroids and sarms. systemic whole-body circulating", "legal_class": null }, { "id": 311, "slug": "tamoxifen", "name": "Tamoxifen", "aliases": [ "Nolvadex", "Nolva", "tamoxifen citrate", "tamoxifen 20 mg" ], "type": "Non-peptide", "category": "Hormone modulators", "goals_use_cases": [ "PCT (discussed)", "gyno scare (discussed)", "SERM (not an AI)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "nolvadex 20", "tamoxifen pct", "nolvadex", "nolva", "pct", "gyno" ], "feel_search": [ "nolvadex", "nolva", "pct", "gyno" ], "summary": "Tamoxifen (Nolvadex) is an oral selective estrogen-receptor modulator, or SERM, also discussed for gynecomastia and post-cycle hormone concerns.", "search_blob": "tamoxifen tamoxifen nolvadex nolva tamoxifen citrate tamoxifen 20 mg nolvadex 20 tamoxifen pct nolvadex nolva pct gyno pct (discussed) gyno scare (discussed) serm (not an ai) nolvadex nolva pct gyno tamoxifen (nolvadex) is an oral selective estrogen-receptor modulator, or serm, also discussed for gynecomastia and post-cycle hormone concerns. one user described a smaller breast lump but severe low mood, fatigue and poor concentration after switching from raloxifene and stopping bupropion. the simultaneous changes prevent assigning the mood burden to tamoxifen alone. tamoxifen is an oral serm discussed for breast-lump symptoms and separately for post-cycle hormone recovery. reports include partial reduction, no change and difficult mood, fog or vision effects. tamoxifen differs from aromatase inhibitors and other serms. medical-label clot, eye, pregnancy and interaction warnings matter; oncology data do not establish a short-pct risk rate. hormone modulators non-peptide systemic tamoxifen, also called nolvadex, is an oral selective estrogen-receptor modulator (serm). breast-lump reports and attempts at post-cycle hormone recovery concern different outcomes; it is not an aromatase inhibitor. systemic whole-body circulating", "legal_class": null }, { "id": 312, "slug": "exemestane", "name": "Exemestane", "aliases": [ "Aromasin", "Asin", "exemestane 25 mg", "suicidal AI" ], "type": "Non-peptide", "category": "Hormone modulators", "goals_use_cases": [ "estradiol control on TRT / AAS (discussed)", "suicidal AI (discussed)", "less crash than Adex (argued)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "aromasin 25", "exemestane 12.5", "aromasin", "asin", "ai crash", "estradiol" ], "feel_search": [ "aromasin", "asin", "ai crash", "estradiol" ], "summary": "Exemestane (Aromasin) is an oral steroidal aromatase inhibitor that irreversibly reduces aromatase activity and lowers new estrogen production.", "search_blob": "exemestane exemestane aromasin asin exemestane 25 mg suicidal ai aromasin 25 exemestane 12.5 aromasin asin ai crash estradiol estradiol control on trt / aas (discussed) suicidal ai (discussed) less crash than adex (argued) aromasin asin ai crash estradiol exemestane (aromasin) is an oral steroidal aromatase inhibitor that irreversibly reduces aromatase activity and lowers new estrogen production. a trt-related account reports very low measured estradiol, stiff painful joints, sexual symptoms and slow improvement. other treatment changes make a recovery clock uncertain. exemestane is an oral aromatase inhibitor that reduces estrogen production. community reports concerning e2 range from less bloat or nipple sensitivity to little change, joint pain and sexual or sleep problems. steroidal describes its chemical class. exemestane differs from tamoxifen, and neither symptoms nor pill half-life establishes estradiol levels or a recovery timetable. hormone modulators non-peptide systemic an oral steroidal aromatase inhibitor that reduces estrogen production by irreversibly inactivating aromatase. community accounts concern hormone co-use and variable benefits and adverse effects. systemic whole-body circulating", "legal_class": null }, { "id": 313, "slug": "liothyronine", "name": "Liothyronine", "aliases": [ "T3", "Cytomel-class talk", "liothyronine 25 mcg", "triiodothyronine" ], "type": "Non-peptide", "category": "Mitochondrial & metabolic compounds", "goals_use_cases": [ "heart", "contest prep (discussed)", "metabolic rate (discussed)", "catabolism (watch-for)", "heart rate (watch-for)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "t3 25mcg", "liothyronine cytomel", "t3", "cytomel", "thyroid cut", "hot" ], "feel_search": [ "t3", "cytomel", "thyroid cut", "hot" ], "summary": "Liothyronine is synthetic T3 thyroid hormone, sold as Cytomel. People discuss it for thyroid replacement and, separately, bodybuilding cuts.", "search_blob": "liothyronine liothyronine t3 cytomel-class talk liothyronine 25 mcg triiodothyronine t3 25mcg liothyronine cytomel t3 cytomel thyroid cut hot heart contest prep (discussed) metabolic rate (discussed) catabolism (watch-for) heart rate (watch-for) t3 cytomel thyroid cut hot liothyronine is synthetic t3 thyroid hormone, sold as cytomel. people discuss it for thyroid replacement and, separately, bodybuilding cuts. some accounts describe more alertness or energy; others describe no benefit, an afternoon crash, anxiety or sleep disruption. liothyronine supplies t3 thyroid hormone. replacement accounts describe improved energy, no benefit, crashes or adverse symptoms; separate prep accounts concern weight loss. the saved label warns against weight-loss use. excess thyroid hormone can affect heart rhythm and bone; stopping reports do not establish a safe recovery calendar. mitochondrial & metabolic compounds non-peptide systemic oral t3 thyroid hormone discussed for thyroid replacement and, separately, bodybuilding cuts. systemic whole-body circulating", "legal_class": null }, { "id": 314, "slug": "dihydroboldenone", "name": "Dihydroboldenone", "aliases": [ "DHB", "1-testosterone", "1-test", "delta-1 DHT", "dihydroboldenone cypionate", "1-testosterone cypionate" ], "type": "Non-peptide", "category": "Hormones in performance discourse", "goals_use_cases": [ "hardening (discussed)", "strength", "EQ-adjacent (discussed)", "injection pain (watch-for)" ], "delivery_methods": [ "intramuscular" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "dihydroboldenone", "1 testosterone", "dhb cyp", "dhb", "1-test", "pip", "equipoise cousin" ], "feel_search": [ "dhb", "1-test", "pip", "equipoise cousin" ], "summary": "Dihydroboldenone (DHB/1-testosterone) is an anabolic steroid discussed as an injection for strength and physique goals; it is distinct from Equipoise.", "search_blob": "dihydroboldenone dihydroboldenone dhb 1-testosterone 1-test delta-1 dht dihydroboldenone cypionate 1-testosterone cypionate dihydroboldenone 1 testosterone dhb cyp dhb 1-test pip equipoise cousin hardening (discussed) strength eq-adjacent (discussed) injection pain (watch-for) dhb 1-test pip equipoise cousin dihydroboldenone (dhb/1-testosterone) is an anabolic steroid discussed as an injection for strength and physique goals; it is distinct from equipoise. stacked-use accounts describe fullness and strength alongside irritability or painful injections. users disagree about how much formulation and individual response explain the pain. dhb is an injectable anabolic steroid discussed for strength and a harder appearance. accounts include useful gains, little change, painful injections and flu-like fatigue, usually with other drugs. u.s. schedule iii as 1-testosterone. contents remain unverified in community accounts; injection pain and apparent benefit cannot authenticate a vial. hormones in performance discourse non-peptide systemic injectable 1-testosterone / dhb in aas talk \u2014 next to eq, not testosterone cypionate. u.s. schedule iii iii systemic whole-body circulating", "legal_class": { "schedule": "III", "label": "U.S. Schedule III" } }, { "id": 315, "slug": "trestolone", "name": "Trestolone", "aliases": [ "MENT", "trest", "trestolone acetate", "7\u03b1-methyl-19-nortestosterone", "MENT acetate" ], "type": "Non-peptide", "category": "Hormones in performance discourse", "goals_use_cases": [ "suppression (discussed)", "estrogen from 19-nor (discussed)", "strength", "libido (split)" ], "delivery_methods": [ "intramuscular" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "trestolone acetate", "ment acetate", "7a-methyl-19-nor", "ment", "trest", "suppressive", "19-nor" ], "feel_search": [ "ment", "trest", "suppressive", "19-nor" ], "summary": "Trestolone, or MENT, is 7\u03b1-methyl-19-nortestosterone, an injectable anabolic-androgenic steroid discussed for muscle and strength.", "search_blob": "trestolone trestolone ment trest trestolone acetate 7\u03b1-methyl-19-nortestosterone ment acetate trestolone acetate ment acetate 7a-methyl-19-nor ment trest suppressive 19-nor suppression (discussed) estrogen from 19-nor (discussed) strength libido (split) ment trest suppressive 19-nor trestolone, or ment, is 7\u03b1-methyl-19-nortestosterone, an injectable anabolic-androgenic steroid discussed for muscle and strength. reports range from little noticeable change to strong gym and libido effects, with nipple sensitivity, water retention or fatigue in some accounts. trestolone is an anabolic-androgenic steroid discussed for fullness, strength and libido. reports also include little benefit, poor sleep, breast symptoms and cardiovascular complaints. not a named csa schedule iii steroid on the 86-item list. boards still treat it as a steroid. analogue rules may apply; this card is not a legal opinion. hormones in performance discourse non-peptide systemic a systemic 19-nor anabolic-androgenic steroid, also called ment. it is distinct from testosterone, nandrolone and trenbolone. systemic whole-body circulating", "legal_class": null }, { "id": 316, "slug": "methasterone", "name": "Methasterone", "aliases": [ "SuperDrol", "Superdrol", "SD", "methyldrostanolone", "methasterone oral" ], "type": "Non-peptide", "category": "Hormones in performance discourse", "goals_use_cases": [ "rapid strength (discussed)", "dry oral (discussed)", "liver (watch-for)", "short run (discussed)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "superdrol 10", "methyldrostanolone", "methasterone", "superdrol", "sdrol", "back pumps", "liver oral" ], "feel_search": [ "superdrol", "sdrol", "back pumps", "liver oral" ], "summary": "Methasterone (Superdrol) is an oral anabolic steroid, discussed for rapid strength and a dense look alongside substantial fatigue and liver-risk concerns.", "search_blob": "methasterone methasterone superdrol superdrol sd methyldrostanolone methasterone oral superdrol 10 methyldrostanolone methasterone superdrol sdrol back pumps liver oral rapid strength (discussed) dry oral (discussed) liver (watch-for) short run (discussed) superdrol sdrol back pumps liver oral methasterone (superdrol) is an oral anabolic steroid, discussed for rapid strength and a dense look alongside substantial fatigue and liver-risk concerns. methasterone, or superdrol, is an oral anabolic steroid discussed for rapid strength and muscle fullness, with conflicting strength outcomes and substantial fatigue and liver concerns. the saved record lists u.s. schedule iii status. short courses do not establish safety, and liver injury has been reported after stopping. hormones in performance discourse non-peptide systemic oral dht-derived anabolic steroid, also called superdrol, discussed for rapid strength and muscle fullness alongside substantial adverse effects. u.s. schedule iii iii systemic whole-body circulating", "legal_class": { "schedule": "III", "label": "U.S. Schedule III" } }, { "id": 317, "slug": "letrozole", "name": "Letrozole", "aliases": [ "Femara", "letro", "letrozole 2.5 mg", "letrozole AI" ], "type": "Non-peptide", "category": "Hormone modulators", "goals_use_cases": [ "estradiol crash (watch-for)", "gyno last-resort (discussed)", "fertility/TTC adjacency", "strong AI (discussed)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "letrozole 2.5", "femara letro", "letro", "femara", "e2 crash", "ai" ], "feel_search": [ "letro", "femara", "e2 crash", "ai" ], "summary": "Letrozole is an aromatase inhibitor that lowers estrogen production; discussions span prescribed fertility care and off-label hormone management.", "search_blob": "letrozole letrozole femara letro letrozole 2.5 mg letrozole ai letrozole 2.5 femara letro letro femara e2 crash ai estradiol crash (watch-for) gyno last-resort (discussed) fertility/ttc adjacency strong ai (discussed) letro femara e2 crash ai letrozole is an aromatase inhibitor that lowers estrogen production; discussions span prescribed fertility care and off-label hormone management. some describe joint aches, fatigue, headaches or flatter mood; others report no noticeable symptoms. experiences differ across fertility care and hormone-use discussions. letrozole reduces estrogen production. breast-symptom and fertility reports describe different goals, with improvement, no noticeable symptoms or difficult joint, mood and sleep effects. fertility, oncology and male hormone-use contexts have different amounts and schedules. symptoms alone do not diagnose low estrogen or show treatment success. hormone modulators non-peptide systemic letrozole, also called femara, is an oral non-steroidal aromatase inhibitor that reduces estrogen production. fertility, oncology and male hormone-use accounts have different goals and schedules. systemic whole-body circulating", "legal_class": null }, { "id": 318, "slug": "raloxifene", "name": "Raloxifene", "aliases": [ "Evista", "ralox", "raloxifene 60 mg", "gyno SERM" ], "type": "Non-peptide", "category": "Hormone modulators", "goals_use_cases": [ "gyno (discussed)", "PCT SERM (discussed)", "vs Nolvadex (discussed)", "lipids (watch-for)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "raloxifene 60", "evista ralox", "ralox", "evista", "gyno serm", "pct" ], "feel_search": [ "ralox", "evista", "gyno serm", "pct" ], "summary": "Raloxifene (Evista) is an oral selective estrogen-receptor modulator, or SERM, discussed in bodybuilding forums for gynecomastia.", "search_blob": "raloxifene raloxifene evista ralox raloxifene 60 mg gyno serm raloxifene 60 evista ralox ralox evista gyno serm pct gyno (discussed) pct serm (discussed) vs nolvadex (discussed) lipids (watch-for) ralox evista gyno serm pct raloxifene (evista) is an oral selective estrogen-receptor modulator, or serm, discussed in bodybuilding forums for gynecomastia. one user reported no noticeable change or side effects after three months; their later switch to tamoxifen also changed another medication. raloxifene is an oral serm discussed for breast lumps, tenderness and puffiness. reports include subjective improvement, no change and worsening; a post-cycle comparison is not proof of hormone recovery. the saved 2026 discussion includes variable results and drug switches. medical-label clot warnings matter, and a response while taking raloxifene does not establish a lasting result after stopping. hormone modulators non-peptide systemic an oral selective estrogen-receptor modulator, or serm, discussed for breast lumps, tenderness and puffiness. it changes estrogen action at receptors rather than stopping production. systemic whole-body circulating", "legal_class": null }, { "id": 319, "slug": "levothyroxine", "name": "Levothyroxine", "aliases": [ "T4", "Synthroid-class talk", "levothyroxine 50 mcg", "L-thyroxine", "levothyroxine sodium" ], "type": "Non-peptide", "category": "Mitochondrial & metabolic compounds", "goals_use_cases": [ "thyroid replacement (discussed)", "contest T4+T3 (discussed)", "TSH (watch-for)", "slow vs T3 (discussed)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "levothyroxine 50", "synthroid t4", "l-thyroxine", "t4", "synthroid", "levothyroxine", "tsh" ], "feel_search": [ "t4", "synthroid", "levothyroxine", "tsh" ], "summary": "Levothyroxine is synthetic T4 used to replace missing thyroid hormone. The body converts T4 into T3; Synthroid is one brand.", "search_blob": "levothyroxine levothyroxine t4 synthroid-class talk levothyroxine 50 mcg l-thyroxine levothyroxine sodium levothyroxine 50 synthroid t4 l-thyroxine t4 synthroid levothyroxine tsh thyroid replacement (discussed) contest t4+t3 (discussed) tsh (watch-for) slow vs t3 (discussed) t4 synthroid levothyroxine tsh levothyroxine is synthetic t4 used to replace missing thyroid hormone. the body converts t4 into t3; synthroid is one brand. reports include steadier energy and improvement in low-thyroid symptoms, but also persistent fatigue or brain fog despite improved tests. levothyroxine supplies t4 thyroid hormone for replacement. accounts include improved energy over days to months and persistent symptoms despite improved tests. t4, t3 and desiccated thyroid contain different hormones. the saved synthroid label warns against obesity treatment and distinguishes full therapeutic effect from early sensations. mitochondrial & metabolic compounds non-peptide systemic oral synthetic t4 thyroid hormone, including the synthroid brand; distinct from t3 and mixed-hormone desiccated thyroid. systemic whole-body circulating", "legal_class": null }, { "id": 320, "slug": "desiccated-thyroid", "name": "Desiccated thyroid", "aliases": [ "NDT", "Armour Thyroid", "NP Thyroid", "Nature-Throid", "WP Thyroid", "DTE", "desiccated thyroid extract", "porcine thyroid" ], "type": "Non-peptide", "category": "Mitochondrial & metabolic compounds", "goals_use_cases": [ "hypothyroid replacement (discussed)", "Armour vs Synthroid (discussed)", "T4+T3 mix (discussed)", "grain dosing (discussed)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "np thyroid", "armour thyroid", "desiccated thyroid", "dte", "armour", "ndt", "desiccated", "nature-throid" ], "feel_search": [ "armour", "np thyroid", "ndt", "desiccated", "nature-throid" ], "summary": "Desiccated thyroid is dried pig thyroid in a tablet for an underactive thyroid. Armour and NP Thyroid supply both T4 and T3 hormones.", "search_blob": "desiccated thyroid desiccated-thyroid ndt armour thyroid np thyroid nature-throid wp thyroid dte desiccated thyroid extract porcine thyroid np thyroid armour thyroid desiccated thyroid dte armour ndt desiccated nature-throid hypothyroid replacement (discussed) armour vs synthroid (discussed) t4+t3 mix (discussed) grain dosing (discussed) armour np thyroid ndt desiccated nature-throid desiccated thyroid is dried pig thyroid in a tablet for an underactive thyroid. armour and np thyroid supply both t4 and t3 hormones. some switch reports describe better energy; others describe no improvement, palpitations, tremor or disrupted sleep. desiccated thyroid supplies t4 and t3 from dried pig thyroid. some switch reports describe better energy; others describe continued fatigue, palpitations or disrupted sleep. it is hormone replacement, not a general energy supplement. extract milligrams are not hormone micrograms. ongoing replacement, additional t3 and product switches have different contexts; dated access concerns do not establish current availability. mitochondrial & metabolic compounds non-peptide systemic porcine desiccated thyroid \u2014 armour / np thyroid / nature-throid. t4+t3 in one grain, not pure t4. systemic whole-body circulating", "legal_class": null }, { "id": 321, "slug": "abs-201", "name": "ABS-201", "aliases": [ "ABS201", "ABS 201", "prolactin receptor antagonist hair", "Absci ABS-201" ], "type": "Non-peptide", "category": "Skin, hair & tissue remodeling", "goals_use_cases": [ "androgenetic alopecia (discussed)", "prolactin-receptor hair (discussed)", "vs HMI-115 (discussed)" ], "delivery_methods": [ "intramuscular" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "abs201", "abs 201", "prolactin receptor antibody", "abs-201", "prolactin hair", "hmi-115" ], "feel_search": [ "abs-201", "prolactin hair", "hmi-115" ], "summary": "ABS-201 is an investigational prolactin-receptor antibody being developed for hair loss.", "search_blob": "abs-201 abs-201 abs201 abs 201 prolactin receptor antagonist hair absci abs-201 abs201 abs 201 prolactin receptor antibody abs-201 prolactin hair hmi-115 androgenetic alopecia (discussed) prolactin-receptor hair (discussed) vs hmi-115 (discussed) abs-201 prolactin hair hmi-115 abs-201 is an investigational prolactin-receptor antibody being developed for hair loss. the inspected discussion covers trial announcements and injection convenience. it provides no firsthand hair-regrowth or day-to-day feel report. abs-201 is an investigational prolactin-receptor antibody being studied for hair loss. the inspected accounts do not establish firsthand regrowth or a consumer regimen for abs-201. trial drug exposure, hoped-for regrowth and community experience are distinct. the saved accounts establish neither a consumer schedule nor scalp-only action. skin, hair & tissue remodeling non-peptide systemic an investigational prolactin-receptor antibody in the saved 2026 hair-loss discussion. the iv and subcutaneous trial routes involve systemic exposure; a hair target does not imply scalp-only action. systemic whole-body circulating", "legal_class": null }, { "id": 322, "slug": "hmi-115", "name": "HMI-115", "aliases": [ "HMI115", "HMI 115", "Hope Medicine HMI-115", "prolactin receptor antibody hair" ], "type": "Non-peptide", "category": "Skin, hair & tissue remodeling", "goals_use_cases": [ "androgenetic alopecia (discussed)", "endometriosis pipeline (adjacent)", "vs ABS-201 (discussed)" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "hmi115", "hmi 115", "hope medicine hair", "hmi-115", "prolactin antibody", "abs-201" ], "feel_search": [ "hmi-115", "prolactin antibody", "abs-201" ], "summary": "HMI-115 is an investigational antibody that blocks the prolactin receptor, being studied for pattern hair loss and endometriosis.", "search_blob": "hmi-115 hmi-115 hmi115 hmi 115 hope medicine hmi-115 prolactin receptor antibody hair hmi115 hmi 115 hope medicine hair hmi-115 prolactin antibody abs-201 androgenetic alopecia (discussed) endometriosis pipeline (adjacent) vs abs-201 (discussed) hmi-115 prolactin antibody abs-201 hmi-115 is an investigational antibody that blocks the prolactin receptor, being studied for pattern hair loss and endometriosis. the reviewed sources do not establish a typical subjective effect. hair counts and trial progress do not tell a user what an injection should feel like. hmi-115 is an experimental prolactin-receptor antibody discussed for pattern hair loss. small early study results and a participant's report do not establish predictable regrowth. the saved trials use subcutaneous injections. no routine consumer dose, measured human half-life or proven maintenance schedule is established by these accounts. skin, hair & tissue remodeling non-peptide systemic investigational prolactin-receptor antibody studied by subcutaneous injection for pattern hair loss, with a separate endometriosis development program. systemic whole-body circulating", "legal_class": null }, { "id": 323, "slug": "1-3-dmaa", "name": "1,3-DMAA", "aliases": [ "DMAA", "1,3-dimethylamylamine", "Methylhexanamine", "Methylhexaneamine", "Geranamine", "1,3-dimethylpentylamine", "2-amino-4-methylhexane", "4-methylhexan-2-amine" ], "type": "Non-peptide", "category": "Cognitive research compounds", "goals_use_cases": [ "pre-workout energy", "focus", "training drive", "perceived endurance", "stimulant crash" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "1 3 dmaa", "13 dmaa", "dmaa", "dimethylamylamine", "geranamine", "methylhexanamine", "methylhexaneamine", "tunnel focus", "locked in", "aggression", "crash", "jitters", "energy", "low appetite" ], "feel_search": [ "tunnel focus", "locked in", "aggression", "crash", "jitters", "energy", "low appetite" ], "summary": "People describe intense workout focus and drive, but also little benefit, physical discomfort and a crash.", "search_blob": "1,3-dmaa 1-3-dmaa dmaa 1,3-dimethylamylamine methylhexanamine methylhexaneamine geranamine 1,3-dimethylpentylamine 2-amino-4-methylhexane 4-methylhexan-2-amine 1 3 dmaa 13 dmaa dmaa dimethylamylamine geranamine methylhexanamine methylhexaneamine tunnel focus locked in aggression crash jitters energy low appetite pre-workout energy focus training drive perceived endurance stimulant crash tunnel focus locked in aggression crash jitters energy low appetite people describe intense workout focus and drive, but also little benefit, physical discomfort and a crash. people describe intense workout focus and drive, but also little benefit, physical discomfort and a crash. cognitive research compounds non-peptide systemic whole-body stimulation discussed around workouts. systemic whole-body circulating", "legal_class": null }, { "id": 324, "slug": "1-4-dmaa", "name": "1,4-DMAA", "aliases": [ "1,4-Dimethylamylamine", "1,4-Dimethylpentylamine", "5-methylhexan-2-amine" ], "type": "Non-peptide", "category": "Stimulants / performance", "goals_use_cases": [ "energy", "workout drive", "focus", "fatigue" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "1,4 DMAA", "1 4 DMAA", "14dmaa", "1-4-dmaa", "1,4-dimethylamylamine", "1,4-dimethylpentylamine", "5-methylhexan-2-amine", "energy", "fatigue", "workout drive", "jittery", "mood lift", "focus" ], "feel_search": [ "energy", "fatigue", "workout drive", "jittery", "mood lift", "focus" ], "summary": "People discuss workout energy and less fatigue, with reports ranging from strong stimulation to disappointing blends.\u2026", "search_blob": "1,4-dmaa 1-4-dmaa 1,4-dimethylamylamine 1,4-dimethylpentylamine 5-methylhexan-2-amine 1,4 dmaa 1 4 dmaa 14dmaa 1-4-dmaa 1,4-dimethylamylamine 1,4-dimethylpentylamine 5-methylhexan-2-amine energy fatigue workout drive jittery mood lift focus energy workout drive focus fatigue energy fatigue workout drive jittery mood lift focus people discuss workout energy and less fatigue, with reports ranging from strong stimulation to disappointing blends.\u2026 people discuss workout energy and less fatigue, with reports ranging from strong stimulation to disappointing blends. mixtures and uncertain product identity limit attribution; stronger stimulation can also impair concentration. stimulants / performance non-peptide systemic discussed for whole-body stimulation during training; mixtures do not isolate its effects. systemic whole-body circulating", "legal_class": null }, { "id": 325, "slug": "3-5-diiodo-l-thyronine", "name": "3,5-Diiodo-L-thyronine", "aliases": [ "3,5-T2", "3,5-diiodothyronine", "3,5-diiodo-L-thyronine (T2)" ], "type": "Non-peptide", "category": "Mitochondrial & metabolic compounds", "goals_use_cases": [ "fat loss (discussed)", "cutting (discussed)", "thyroid suppression (watch-for)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "3 5 T2", "3 5 diiodo l thyronine", "diiodothyronine", "T2 thyroid", "thyroid cutting", "no extra fat loss", "lethargy", "sweating", "thyroid suppression" ], "feel_search": [ "no extra fat loss", "lethargy", "sweating", "T2 thyroid", "thyroid suppression" ], "summary": "People discuss 3,5-T2 for cutting, with mixed results and disputed thyroid safety.", "search_blob": "3,5-diiodo-l-thyronine 3-5-diiodo-l-thyronine 3,5-t2 3,5-diiodothyronine 3,5-diiodo-l-thyronine (t2) 3 5 t2 3 5 diiodo l thyronine diiodothyronine t2 thyroid thyroid cutting no extra fat loss lethargy sweating thyroid suppression fat loss (discussed) cutting (discussed) thyroid suppression (watch-for) no extra fat loss lethargy sweating t2 thyroid thyroid suppression people discuss 3,5-t2 for cutting, with mixed results and disputed thyroid safety. people discuss 3,5-t2 for cutting, with mixed results and disputed thyroid safety. mitochondrial & metabolic compounds non-peptide systemic people discuss oral products for whole-body metabolic effects. systemic whole-body circulating", "legal_class": null }, { "id": 326, "slug": "acd856", "name": "ACD856", "aliases": [ "ACD-856", "ACD 856", "NeuroRestore ACD856" ], "type": "Non-peptide", "category": "Cognitive research compounds", "goals_use_cases": [ "cognition", "brain fog", "mood", "motivation", "neuroplasticity discussion" ], "delivery_methods": [ "oral", "sublingual (reported)" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "acd856", "acd-856", "acd 856", "NeuroRestore ACD856", "IGF-1R Modulator 1 supplier label", "brain fog", "emotional blunting", "mental fatigue", "mood", "motivation", "tiredness", "libido" ], "feel_search": [ "brain fog", "mood", "motivation", "tiredness", "emotional blunting", "libido" ], "summary": "People discuss less brain fog and steadier mood, with tiredness and nonresponse also reported.", "search_blob": "acd856 acd856 acd-856 acd 856 neurorestore acd856 acd856 acd-856 acd 856 neurorestore acd856 igf-1r modulator 1 supplier label brain fog emotional blunting mental fatigue mood motivation tiredness libido cognition brain fog mood motivation neuroplasticity discussion brain fog mood motivation tiredness emotional blunting libido people discuss less brain fog and steadier mood, with tiredness and nonresponse also reported. people discuss less brain fog and steadier mood, with tiredness and nonresponse also reported. cognitive research compounds non-peptide systemic discussed for whole-body exposure and brain effects; supplier formulations are not verified clinical equivalents. systemic whole-body circulating", "legal_class": null }, { "id": 327, "slug": "acetildenafil", "name": "Acetildenafil", "aliases": [ "Hongdenafil" ], "type": "Non-peptide", "category": "Sexual / reproductive", "goals_use_cases": [ "erectile function discussion", "sexual performance", "PDE5 analogue comparison" ], "delivery_methods": [ "oral", "nasal", "rectal (isolated report)" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "acetildenafil", "hongdenafil", "acetildenifil", "acetidenifil", "acetyldenafil", "erection quality", "harder erections", "flushing", "headache", "sinus pressure", "stim dick", "prolonged erection" ], "feel_search": [ "erection quality", "harder erections", "flushing", "headache", "sinus pressure", "stim dick", "prolonged erection" ], "summary": "People report firmer erections, but weak response and unwanted effects also appear.", "search_blob": "acetildenafil acetildenafil hongdenafil acetildenafil hongdenafil acetildenifil acetidenifil acetyldenafil erection quality harder erections flushing headache sinus pressure stim dick prolonged erection erectile function discussion sexual performance pde5 analogue comparison erection quality harder erections flushing headache sinus pressure stim dick prolonged erection people report firmer erections, but weak response and unwanted effects also appear. people report firmer erections, but weak response and unwanted effects also appear. sexual / reproductive non-peptide systemic discussed for erections, with effects and risks that can extend beyond sexual function. systemic whole-body circulating", "legal_class": null }, { "id": 328, "slug": "adrafinil", "name": "Adrafinil", "aliases": [ "Olmifon", "CRL-40028", "CRL 40028", "adrafinyl" ], "type": "Non-peptide", "category": "Wakefulness agents in productivity discourse", "goals_use_cases": [ "wakefulness", "focus (discussed)", "productivity (discussed)" ], "delivery_methods": [ "oral", "sublingual" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "adrafinyl", "adrafanil", "crl40028", "olmifon", "awake", "brain fog", "weak effects", "fatigue", "anxiety", "insomnia", "focus" ], "feel_search": [ "awake", "brain fog", "weak effects", "fatigue", "anxiety", "insomnia", "focus" ], "summary": "Adrafinil is discussed for staying awake and focused, with both useful and weak responses.", "search_blob": "adrafinil adrafinil olmifon crl-40028 crl 40028 adrafinyl adrafinyl adrafanil crl40028 olmifon awake brain fog weak effects fatigue anxiety insomnia focus wakefulness focus (discussed) productivity (discussed) awake brain fog weak effects fatigue anxiety insomnia focus adrafinil is discussed for staying awake and focused, with both useful and weak responses. adrafinil is discussed for staying awake and focused, with both useful and weak responses. anxiety, fatigue and sleep disruption can outweigh the benefit; serious skin reactions have been reported. wakefulness agents in productivity discourse non-peptide systemic a whole-body wakefulness compound discussed in oral reports. no named csa listing found in dated screen systemic whole-body circulating", "legal_class": { "schedule": "", "label": "No named CSA listing found in dated screen" } }, { "id": 329, "slug": "agomelatine", "name": "Agomelatine", "aliases": [ "Valdoxan", "Thymanax" ], "type": "Non-peptide", "category": "Sleep / mood", "goals_use_cases": [ "sleep", "mood", "motivation (reported)", "early waking (reported downside)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "agomelatin", "agomelatine", "valdoxan", "sleep", "low mood", "motivation", "early waking", "vivid dreams", "quiet mind", "dizziness" ], "feel_search": [ "low mood", "motivation", "early waking", "vivid dreams", "quiet mind", "dizziness" ], "summary": "**Valdoxan is a medicine containing agomelatine.** It is a non-peptide prescription antidepressant, supplied\u2026", "search_blob": "agomelatine agomelatine valdoxan thymanax agomelatin agomelatine valdoxan sleep low mood motivation early waking vivid dreams quiet mind dizziness sleep mood motivation (reported) early waking (reported downside) low mood motivation early waking vivid dreams quiet mind dizziness **valdoxan is a medicine containing agomelatine.** it is a non-peptide prescription antidepressant, supplied\u2026 sleep / mood non-peptide systemic an oral antidepressant discussed for sleep and mood. systemic whole-body circulating", "legal_class": null }, { "id": 330, "slug": "alt-711", "name": "ALT-711 (Alagebrium)", "aliases": [ "Alagebrium", "Alagebrium chloride", "ALT711", "ALT 711" ], "type": "Non-peptide", "category": "Longevity & bioregulators", "goals_use_cases": [ "glycation / AGE crosslink discussion", "arterial stiffness discussion", "skin elasticity discussion", "longevity" ], "delivery_methods": [ "oral", "topical" ], "discussion_popularity": "Emerging", "reach": "Mixed", "misspellings_search_terms": [ "ALT-711", "ALT711", "ALT 711", "alagebrium", "alagebrium chloride", "ALT-111", "crosslink breaker", "AGE breaker", "glucosepane", "skin elasticity", "arterial stiffness", "stiff arteries", "wrinkles", "glycation" ], "feel_search": [ "skin elasticity", "stiff arteries", "wrinkles", "glycation" ], "summary": "People discuss ALT-711 for glycation-related skin and vascular stiffness; individual benefit remains uncertain.", "search_blob": "alt-711 (alagebrium) alt-711 alagebrium alagebrium chloride alt711 alt 711 alt-711 alt711 alt 711 alagebrium alagebrium chloride alt-111 crosslink breaker age breaker glucosepane skin elasticity arterial stiffness stiff arteries wrinkles glycation glycation / age crosslink discussion arterial stiffness discussion skin elasticity discussion longevity skin elasticity stiff arteries wrinkles glycation people discuss alt-711 for glycation-related skin and vascular stiffness; individual benefit remains uncertain. people discuss alt-711 for glycation-related skin and vascular stiffness; individual benefit remains uncertain. longevity & bioregulators non-peptide mixed oral longevity discussion and topical skin experimentation involve different exposures. mixed local systemic", "legal_class": null }, { "id": 331, "slug": "aniracetam", "name": "Aniracetam", "aliases": [ "1-(4-methoxybenzoyl)-2-pyrrolidinone", "1-p-anisoyl-2-pyrrolidinone" ], "type": "Non-peptide", "category": "Cognitive research compounds", "goals_use_cases": [ "cognition", "focus", "mood", "social ease (reported)", "sensory changes (reported)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "aniracetam", "ani", "aniracitam", "racetam", "calmer focus", "visual perception", "irritability", "lethargy", "focus", "calm", "sensory changes", "tiredness" ], "feel_search": [ "focus", "calm", "irritability", "sensory changes", "visual perception", "tiredness", "lethargy" ], "summary": "People describe calmer focus or social ease, but also no effect, tiredness and irritability.", "search_blob": "aniracetam aniracetam 1-(4-methoxybenzoyl)-2-pyrrolidinone 1-p-anisoyl-2-pyrrolidinone aniracetam ani aniracitam racetam calmer focus visual perception irritability lethargy focus calm sensory changes tiredness cognition focus mood social ease (reported) sensory changes (reported) focus calm irritability sensory changes visual perception tiredness lethargy people describe calmer focus or social ease, but also no effect, tiredness and irritability. people describe calmer focus or social ease, but also no effect, tiredness and irritability. cognitive research compounds non-peptide systemic an oral racetam discussed for changes in focus, mood and perception. systemic whole-body circulating", "legal_class": null }, { "id": 332, "slug": "arimistane", "name": "Arimistane", "aliases": [ "Androsta-3,5-diene-7,17-dione", "Androst-3,5-diene-7,17-dione" ], "type": "Non-peptide", "category": "Hormone modulators", "goals_use_cases": [ "estrogen-control discussion", "PCT (discussed)", "dry appearance (discussed)", "lipid and hormone lab discussion" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "armistane", "arimistane pct", "androsta 3 5 diene 7 17 dione", "arimistane lipids", "arimistane vs arimidex", "dry look", "water weight", "breast tenderness", "achy joints", "irritability", "acne" ], "feel_search": [ "dry look", "water weight", "breast tenderness", "achy joints", "irritability", "acne" ], "summary": "Arimistane is discussed for a drier physique, estrogen-related symptoms and post-cycle therapy (PCT). Reports include\u2026", "search_blob": "arimistane arimistane androsta-3,5-diene-7,17-dione androst-3,5-diene-7,17-dione armistane arimistane pct androsta 3 5 diene 7 17 dione arimistane lipids arimistane vs arimidex dry look water weight breast tenderness achy joints irritability acne estrogen-control discussion pct (discussed) dry appearance (discussed) lipid and hormone lab discussion dry look water weight breast tenderness achy joints irritability acne arimistane is discussed for a drier physique, estrogen-related symptoms and post-cycle therapy (pct). reports include\u2026 arimistane is discussed for a drier physique, estrogen-related symptoms and post-cycle therapy (pct). reports include a flatter-looking stomach or less breast tenderness, no apparent estrogen change, and aching joints or irritability. those mixed experiences do not establish reliable estrogen control or recovery after hormone use. reported benefits, uncertain estrogen control and material cautions need to be read together. hormone modulators non-peptide systemic discussed as an oral compound with whole-body hormonal effects. systemic whole-body circulating", "legal_class": null }, { "id": 333, "slug": "bemethyl", "name": "Bemethyl", "aliases": [ "Bemitil", "Metaprot", "Bemetil", "Bemithyl", "Bemythyl", "Bemaktor", "Ethylthiobenzimidazole", "2-(ethylthio)benzimidazole" ], "type": "Non-peptide", "category": "Performance / endurance", "goals_use_cases": [ "fatigue", "endurance", "alertness", "mental energy", "performance" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "Bemitil", "Metaprot", "Bemetil", "Bemithyl", "Bemythyl", "Bemaktor", "Ethylthiobenzimidazole", "2-(ethylthio)benzimidazole", "bemethyl hbr", "bemethyl free base", "bimitil", "actoprotector", "brain fog", "insomnia", "heartburn", "fatigue", "stamina", "mental energy", "alertness", "sleep disruption" ], "feel_search": [ "fatigue", "stamina", "brain fog", "mental energy", "alertness", "sleep disruption", "heartburn" ], "summary": "People discuss less physical fatigue and more alertness, with insomnia and mixed responses.", "search_blob": "bemethyl bemethyl bemitil metaprot bemetil bemithyl bemythyl bemaktor ethylthiobenzimidazole 2-(ethylthio)benzimidazole bemitil metaprot bemetil bemithyl bemythyl bemaktor ethylthiobenzimidazole 2-(ethylthio)benzimidazole bemethyl hbr bemethyl free base bimitil actoprotector brain fog insomnia heartburn fatigue stamina mental energy alertness sleep disruption fatigue endurance alertness mental energy performance fatigue stamina brain fog mental energy alertness sleep disruption heartburn people discuss less physical fatigue and more alertness, with insomnia and mixed responses. people discuss less physical fatigue and more alertness, with insomnia and mixed responses. free-base bemethyl and metaprot/hbr reports are not interchangeable. performance / endurance non-peptide systemic whole-body fatigue and alertness talk, with sleep and digestive tradeoffs. systemic whole-body circulating", "legal_class": null }, { "id": 334, "slug": "bpap", "name": "BPAP", "aliases": [ "Benzofuranylpropylaminopentane", "(-)-BPAP", "R-(-)-BPAP", "FPFS-1169", "R-(-)-1-(benzofuran-2-yl)-2-propylaminopentane hydrochloride" ], "type": "Non-peptide", "category": "Cognitive research compounds", "goals_use_cases": [ "mood", "focus", "social enjoyment", "motivation" ], "delivery_methods": [ "oral", "sublingual" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "bpap", "benzofuranylpropylaminopentane", "FPFS-1169", "BPAP vs PPAP", "subtle mood", "social enjoyment", "no effect", "focus" ], "feel_search": [ "subtle mood", "social enjoyment", "focus", "no effect" ], "summary": "BPAP is discussed for subtle mood, social enjoyment and focus, with mixed or absent effects.", "search_blob": "bpap bpap benzofuranylpropylaminopentane (-)-bpap r-(-)-bpap fpfs-1169 r-(-)-1-(benzofuran-2-yl)-2-propylaminopentane hydrochloride bpap benzofuranylpropylaminopentane fpfs-1169 bpap vs ppap subtle mood social enjoyment no effect focus mood focus social enjoyment motivation subtle mood social enjoyment focus no effect bpap is discussed for subtle mood, social enjoyment and focus, with mixed or absent effects. bpap is discussed for subtle mood, social enjoyment and focus, with mixed or absent effects. cognitive research compounds non-peptide systemic discussed for mood and attention rather than a local body site. systemic whole-body circulating", "legal_class": null }, { "id": 335, "slug": "capromorelin", "name": "Capromorelin", "aliases": [ "CP-424391", "CP-424,391", "Capromorelin tartrate", "Entyce (veterinary formulation)", "Elura (veterinary formulation)" ], "type": "Non-peptide", "category": "Growth hormone axis", "goals_use_cases": [ "appetite (discussed)", "sleep (mixed reports)", "lean mass (research context)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "capromorelin", "capro", "cp 424391", "capromorelin tartrate", "Entyce", "Elura", "hunger", "appetite", "bloating", "insomnia", "tiredness", "sleep" ], "feel_search": [ "hunger", "appetite", "bloating", "insomnia", "tiredness", "sleep" ], "summary": "People discuss stronger appetite and mixed sleep effects.", "search_blob": "capromorelin capromorelin cp-424391 cp-424,391 capromorelin tartrate entyce (veterinary formulation) elura (veterinary formulation) capromorelin capro cp 424391 capromorelin tartrate entyce elura hunger appetite bloating insomnia tiredness sleep appetite (discussed) sleep (mixed reports) lean mass (research context) hunger appetite bloating insomnia tiredness sleep people discuss stronger appetite and mixed sleep effects. people discuss stronger appetite and mixed sleep effects. bloating, tiredness and suspected insomnia appear in human reports. growth hormone axis non-peptide systemic discussed for whole-body appetite and sleep effects. systemic whole-body circulating", "legal_class": null }, { "id": 336, "slug": "ce-123", "name": "CE-123", "aliases": [ "CE123", "CE 123", "S-CE-123", "(S)-CE-123" ], "type": "Non-peptide", "category": "Wakefulness agents in productivity discourse", "goals_use_cases": [ "wakefulness (discussed)", "focus (discussed)", "motivation (discussed)" ], "delivery_methods": [ "unspecified in inspected firsthand reports" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "ce123", "ce 123", "s ce 123", "S-CE-123", "(S)-CE-123", "modafinil analogue", "modafinil analog", "restless focus", "short focus boost", "wakefulness", "motivation", "focus", "task switching", "restless", "urine odor" ], "feel_search": [ "wakefulness", "motivation", "focus", "task switching", "restless", "urine odor" ], "summary": "CE-123 is an experimental modafinil relative discussed for wakefulness, motivation and focus. Reports range from a\u2026", "search_blob": "ce-123 ce-123 ce123 ce 123 s-ce-123 (s)-ce-123 ce123 ce 123 s ce 123 s-ce-123 (s)-ce-123 modafinil analogue modafinil analog restless focus short focus boost wakefulness motivation focus task switching restless urine odor wakefulness (discussed) focus (discussed) motivation (discussed) wakefulness motivation focus task switching restless urine odor ce-123 is an experimental modafinil relative discussed for wakefulness, motivation and focus. reports range from a\u2026 ce-123 is an experimental modafinil relative discussed for wakefulness, motivation and focus. reports range from a useful mental lift to ordinary modafinil-like effects or restless task-switching. feeling more activated does not necessarily mean getting useful work done. activation, uncertain product identity and conflicting felt duration limit the comparisons. wakefulness agents in productivity discourse non-peptide systemic discussed for whole-body alertness and attention, with route unstated in the inspected accounts. systemic whole-body circulating", "legal_class": null }, { "id": 337, "slug": "coluracetam", "name": "Coluracetam", "aliases": [ "MKC-231", "MKC 231", "BCI-540", "BCI 540", "Colouracetam" ], "type": "Non-peptide", "category": "Cognitive research compounds", "goals_use_cases": [ "mood", "cognition", "focus / attention", "sensory vividness (discussed)", "calm / anxiety discussion" ], "delivery_methods": [ "oral", "sublingual" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "coluracetam", "colouracetam", "coloracetam", "colu", "MKC-231", "MKC 231", "BCI-540", "BCI 540", "HD vision", "brain fog", "mood lift", "calm", "initiative", "anxiety", "drowsiness" ], "feel_search": [ "mood lift", "calm", "brain fog", "HD vision", "initiative", "anxiety", "drowsiness" ], "summary": "People describe mood lift, calm or sensory vividness; others report no change or cognitive dulling.", "search_blob": "coluracetam coluracetam mkc-231 mkc 231 bci-540 bci 540 colouracetam coluracetam colouracetam coloracetam colu mkc-231 mkc 231 bci-540 bci 540 hd vision brain fog mood lift calm initiative anxiety drowsiness mood cognition focus / attention sensory vividness (discussed) calm / anxiety discussion mood lift calm brain fog hd vision initiative anxiety drowsiness people describe mood lift, calm or sensory vividness; others report no change or cognitive dulling. people describe mood lift, calm or sensory vividness; others report no change or cognitive dulling. cognitive research compounds non-peptide systemic swallowed or held under the tongue in the main reports; effects are discussed as whole-body and cognitive. systemic whole-body circulating", "legal_class": null }, { "id": 338, "slug": "compound-7p", "name": "Compound 7P", "aliases": [ "Compound 7p", "Compound-7P", "CAS 1890208-58-8" ], "type": "Non-peptide", "category": "Cognitive research compounds", "goals_use_cases": [ "cognition discussion", "nerve regeneration research", "mental clarity (anecdotal)", "learning (claimed)" ], "delivery_methods": [ "oral", "sublingual" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "compound 7p", "compound-7p", "7p neuroregeneration", "1890208-58-8", "axon regeneration", "nerve repair", "sharp mind", "mental clarity", "no effect", "tiredness", "insomnia" ], "feel_search": [ "mental clarity", "sharp mind", "no effect", "tiredness", "insomnia" ], "summary": "Experimental Compound 7P draws nerve-repair and clearer-thinking interest, with sparse and mixed reports.", "search_blob": "compound 7p compound-7p compound 7p compound-7p cas 1890208-58-8 compound 7p compound-7p 7p neuroregeneration 1890208-58-8 axon regeneration nerve repair sharp mind mental clarity no effect tiredness insomnia cognition discussion nerve regeneration research mental clarity (anecdotal) learning (claimed) mental clarity sharp mind no effect tiredness insomnia experimental compound 7p draws nerve-repair and clearer-thinking interest, with sparse and mixed reports. experimental compound 7p draws nerve-repair and clearer-thinking interest, with sparse and mixed reports. no measured human half-life or dependable course emerges from these sources. cognitive research compounds non-peptide systemic oral and sublingual use is discussed for whole-person effects; human brain exposure is unresolved. systemic whole-body circulating", "legal_class": null }, { "id": 339, "slug": "dada", "name": "DADA", "aliases": [ "Diisopropylamine dichloroacetate", "Diisopropylammonium dichloroacetate" ], "type": "Non-peptide", "category": "Metabolic research compounds", "goals_use_cases": [ "endurance discussion", "energy discussion", "ME/CFS metabolic discussion" ], "delivery_methods": [ "oral", "injected", "subcutaneous" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "dada", "diisopropylamine dichloroacetate", "diisopropylammonium dichloroacetate", "dada peptide", "PDK4", "energy", "endurance", "fatigue", "weakness", "faintness", "skin pain", "urinary difficulty" ], "feel_search": [ "energy", "endurance", "fatigue", "weakness", "faintness", "skin pain", "urinary difficulty" ], "summary": "Endurance promotion and ME/CFS metabolic questions, with sparse independent benefit evidence and important adverse\u2026", "search_blob": "dada dada diisopropylamine dichloroacetate diisopropylammonium dichloroacetate dada diisopropylamine dichloroacetate diisopropylammonium dichloroacetate dada peptide pdk4 energy endurance fatigue weakness faintness skin pain urinary difficulty endurance discussion energy discussion me/cfs metabolic discussion energy endurance fatigue weakness faintness skin pain urinary difficulty endurance promotion and me/cfs metabolic questions, with sparse independent benefit evidence and important adverse\u2026 endurance promotion and me/cfs metabolic questions, with sparse independent benefit evidence and important adverse reports. metabolic research compounds non-peptide systemic discussed for whole-body energy and endurance rather than a local effect. systemic whole-body circulating", "legal_class": null }, { "id": 340, "slug": "emodin", "name": "Emodin", "aliases": [ "1,3,8-trihydroxy-6-methylanthraquinone" ], "type": "Non-peptide", "category": "Mitochondrial & metabolic compounds", "goals_use_cases": [ "sleep (discussed)", "relaxation (discussed)", "bowel effects", "stress (discussed)" ], "delivery_methods": [ "oral", "topical" ], "discussion_popularity": "Emerging", "reach": "Mixed", "misspellings_search_terms": [ "emodin", "Lapodin", "beta-lapachone blend", "cortisol blocker", "anthraquinone", "calm", "sleep", "bowel movements", "stomach discomfort", "rash", "worse sleep" ], "feel_search": [ "calm", "sleep", "bowel movements", "stomach discomfort", "rash", "worse sleep" ], "summary": "People discuss emodin-containing products for calmer feelings, sleep and bowel effects; experiences include no benefit\u2026", "search_blob": "emodin emodin 1,3,8-trihydroxy-6-methylanthraquinone emodin lapodin beta-lapachone blend cortisol blocker anthraquinone calm sleep bowel movements stomach discomfort rash worse sleep sleep (discussed) relaxation (discussed) bowel effects stress (discussed) calm sleep bowel movements stomach discomfort rash worse sleep people discuss emodin-containing products for calmer feelings, sleep and bowel effects; experiences include no benefit\u2026 people discuss emodin-containing products for calmer feelings, sleep and bowel effects; experiences include no benefit and unpleasant effects. mitochondrial & metabolic compounds non-peptide mixed people describe whole-body effects from oral products and topical blends. mixed local systemic", "legal_class": null }, { "id": 341, "slug": "emoxypine", "name": "Emoxypine succinate", "aliases": [ "Emoxypine", "Mexidol", "Methylethylpiridinol succinate" ], "type": "Non-peptide", "category": "Cognitive research compounds", "goals_use_cases": [ "anxiety discussion", "stress", "mood", "cognition", "brain fog" ], "delivery_methods": [ "oral", "sublingual" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "emoxypine", "emoxipine", "emoxepine", "emoxypine succinate", "mexidol", "methylethylpiridinol succinate", "physical tension", "stress spikes", "social anxiety", "brain fog" ], "feel_search": [], "summary": "**This article focuses on Emoxypine succinate.** It is a small molecule, not a peptide. FDA\u2019s identity\u2026", "search_blob": "emoxypine succinate emoxypine emoxypine mexidol methylethylpiridinol succinate emoxypine emoxipine emoxepine emoxypine succinate mexidol methylethylpiridinol succinate physical tension stress spikes social anxiety brain fog anxiety discussion stress mood cognition brain fog **this article focuses on emoxypine succinate.** it is a small molecule, not a peptide. fda\u2019s identity\u2026 cognitive research compounds non-peptide systemic people discuss it for calmer stress responses and less physical tension. systemic whole-body circulating", "legal_class": null }, { "id": 342, "slug": "fasoracetam", "name": "Fasoracetam", "aliases": [ "NS-105", "NS105", "AEVI-001", "AEVI001", "NFC-1 (clinical fasoracetam monohydrate)", "LAM-105 (development code)" ], "type": "Non-peptide", "category": "Cognitive research compounds", "goals_use_cases": [ "cognition", "focus", "social anxiety (discussed)", "mood", "phenibut tolerance (disputed)" ], "delivery_methods": [ "oral", "sublingual" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "fasoracetam", "faso", "fascoracetam", "fasoracteam", "ns 105", "nfc 1", "aevi 001", "lam 105", "calm focus", "brain fog", "GABA-B", "phenibut tolerance", "social anxiety", "sleep disruption", "racing thoughts", "no effect" ], "feel_search": [ "calm focus", "social anxiety", "brain fog", "sleep disruption", "racing thoughts", "no effect" ], "summary": "Fasoracetam is a synthetic nootropic discussed for calmer focus, social anxiety and changes in phenibut response.\u2026", "search_blob": "fasoracetam fasoracetam ns-105 ns105 aevi-001 aevi001 nfc-1 (clinical fasoracetam monohydrate) lam-105 (development code) fasoracetam faso fascoracetam fasoracteam ns 105 nfc 1 aevi 001 lam 105 calm focus brain fog gaba-b phenibut tolerance social anxiety sleep disruption racing thoughts no effect cognition focus social anxiety (discussed) mood phenibut tolerance (disputed) calm focus social anxiety brain fog sleep disruption racing thoughts no effect fasoracetam is a synthetic nootropic discussed for calmer focus, social anxiety and changes in phenibut response.\u2026 fasoracetam is a synthetic nootropic discussed for calmer focus, social anxiety and changes in phenibut response. reports range from useful calm to no effect, poor sleep or worse experiences, especially in complicated stacks and withdrawal histories. community accounts do not establish safety or effectiveness. cognitive research compounds non-peptide systemic people discuss whole-body effects on attention, mood and anxiety. systemic whole-body circulating", "legal_class": null }, { "id": 343, "slug": "fenbendazole", "name": "Fenbendazole", "aliases": [ "Fenben", "FBZ", "FZ", "Panacur C (veterinary brand)" ], "type": "Non-peptide", "category": "Metabolic & longevity adjacents", "goals_use_cases": [ "cancer self-experimentation (discussed)", "repurposed-drug claims", "liver-injury discussion" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "fenbendazole", "fenben", "FBZ", "FZ", "fendbendazole", "fenbendazol", "Panacur C", "dog dewormer cancer", "Joe Tippens", "cancer remission claims", "liver enzymes", "tumor shrinkage claims", "no active disease", "stomach upset", "jaundice", "dark urine" ], "feel_search": [ "tumor shrinkage claims", "no active disease", "stomach upset", "jaundice", "dark urine", "liver enzymes" ], "summary": "People discuss this animal dewormer for cancer self-experimentation; efficacy is unestablished.", "search_blob": "fenbendazole fenbendazole fenben fbz fz panacur c (veterinary brand) fenbendazole fenben fbz fz fendbendazole fenbendazol panacur c dog dewormer cancer joe tippens cancer remission claims liver enzymes tumor shrinkage claims no active disease stomach upset jaundice dark urine cancer self-experimentation (discussed) repurposed-drug claims liver-injury discussion tumor shrinkage claims no active disease stomach upset jaundice dark urine liver enzymes people discuss this animal dewormer for cancer self-experimentation; efficacy is unestablished. people discuss this animal dewormer for cancer self-experimentation; efficacy is unestablished. testimonials coexist with human liver-injury reports. metabolic & longevity adjacents non-peptide systemic people discuss oral use for whole-body cancer effects; this is an unproven claim. systemic whole-body circulating", "legal_class": null }, { "id": 344, "slug": "fladrafinil", "name": "Fladrafinil", "aliases": [ "CRL-40,941", "CRL-40941", "CRL 40941", "Fluorafinil", "Bisfluoroadrafinil", "bis(4-fluorophenyl)-Adrafinil" ], "type": "Non-peptide", "category": "Wakefulness agents in productivity discourse", "goals_use_cases": [ "wakefulness", "focus (discussed)", "productivity (discussed)" ], "delivery_methods": [ "oral", "nasal" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "fladrafanil", "fl-adrafinil", "crl 40 941", "crl40941", "staying awake", "focus", "stimulation", "tolerance", "no effect", "anxiety", "insomnia", "body odor" ], "feel_search": [ "staying awake", "focus", "stimulation", "tolerance", "no effect", "anxiety", "insomnia", "body odor" ], "summary": "Fladrafinil is a research compound people discuss for staying awake, feeling stimulated and getting through work. Some\u2026", "search_blob": "fladrafinil fladrafinil crl-40,941 crl-40941 crl 40941 fluorafinil bisfluoroadrafinil bis(4-fluorophenyl)-adrafinil fladrafanil fl-adrafinil crl 40 941 crl40941 staying awake focus stimulation tolerance no effect anxiety insomnia body odor wakefulness focus (discussed) productivity (discussed) staying awake focus stimulation tolerance no effect anxiety insomnia body odor fladrafinil is a research compound people discuss for staying awake, feeling stimulated and getting through work. some\u2026 fladrafinil is a research compound people discuss for staying awake, feeling stimulated and getting through work. some describe a noticeable lift; others get little benefit or an uncomfortable, lingering effect. it is distinct from flmodafinil, despite the similar name. reports include little benefit, anxiety, insomnia and rapid tolerance. wakefulness agents in productivity discourse non-peptide systemic discussed for alertness and focus, rather than a local treatment. systemic whole-body circulating", "legal_class": null }, { "id": 345, "slug": "flmodafinil", "name": "Flmodafinil", "aliases": [ "CRL-40,940", "CRL-40940", "Bisfluoromodafinil", "Lauflumide", "FL-modafinil" ], "type": "Non-peptide", "category": "Wakefulness agents in productivity discourse", "goals_use_cases": [ "wakefulness", "focus (discussed)", "productivity (discussed)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "flmodafonil", "flmoda", "fluoromodafinil", "NLS-4", "CRL 40940", "staying awake", "focus", "brain fog", "no effect", "tolerance", "insomnia", "crash" ], "feel_search": [ "staying awake", "focus", "brain fog", "no effect", "tolerance", "insomnia", "crash" ], "summary": "Flmodafinil is a fluorinated relative of modafinil discussed for staying awake and sustaining focus. Some people\u2026", "search_blob": "flmodafinil flmodafinil crl-40,940 crl-40940 bisfluoromodafinil lauflumide fl-modafinil flmodafonil flmoda fluoromodafinil nls-4 crl 40940 staying awake focus brain fog no effect tolerance insomnia crash wakefulness focus (discussed) productivity (discussed) staying awake focus brain fog no effect tolerance insomnia crash flmodafinil is a fluorinated relative of modafinil discussed for staying awake and sustaining focus. some people\u2026 flmodafinil is a fluorinated relative of modafinil discussed for staying awake and sustaining focus. some people describe easier work or study; others feel little, lose the initial effect, or struggle with sleep. the accounts do not establish safe or effective use. sleep disruption, uneven response and unverified product identity complicate the reports. wakefulness agents in productivity discourse non-peptide systemic people discuss whole-body wakefulness and mental focus. no confirmed scheduled identity in dated name screen systemic whole-body circulating", "legal_class": { "schedule": "", "label": "No confirmed scheduled identity in dated name screen" } }, { "id": 346, "slug": "gb-115", "name": "GB-115", "aliases": [ "GB115", "GB 115", "\u0413\u0411-115", "Ranquilon", "Rankvilon", "\u0420\u0430\u043d\u043a\u0432\u0438\u043b\u043e\u043d", "N-(6-phenylhexanoyl)glycyl-L-tryptophanamide" ], "type": "Peptide", "category": "Cognitive / nootropic peptides", "goals_use_cases": [ "anxiety discussion", "social anxiety discussion", "rumination", "mood", "stress" ], "delivery_methods": [ "nasal", "oral", "sublingual (reported)" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "gb115", "gb 115", "gb-115", "\u0433\u0431-115", "ranquilon", "rankvilon", "social anxiety", "rumination", "body tension", "calm without fog", "irritability", "no benefit" ], "feel_search": [ "social anxiety", "rumination", "body tension", "calm without fog", "irritability", "no benefit" ], "summary": "Some self-experimenters describe less anxiety and easier daily interactions.", "search_blob": "gb-115 gb-115 gb115 gb 115 \u0433\u0431-115 ranquilon rankvilon \u0440\u0430\u043d\u043a\u0432\u0438\u043b\u043e\u043d n-(6-phenylhexanoyl)glycyl-l-tryptophanamide gb115 gb 115 gb-115 \u0433\u0431-115 ranquilon rankvilon social anxiety rumination body tension calm without fog irritability no benefit anxiety discussion social anxiety discussion rumination mood stress social anxiety rumination body tension calm without fog irritability no benefit some self-experimenters describe less anxiety and easier daily interactions. some self-experimenters describe less anxiety and easier daily interactions. others report no relief or become irritable; several positive accounts include other compounds. cognitive / nootropic peptides peptide systemic discussed for whole-body tension and anxious thoughts. systemic whole-body circulating", "legal_class": null }, { "id": 347, "slug": "gc-1-sobetirome", "name": "GC-1 (Sobetirome)", "aliases": [ "Sobetirome", "GC-1", "GC1", "GC 1", "QRX-431", "QRX 431" ], "type": "Non-peptide", "category": "Mitochondrial & metabolic compounds", "goals_use_cases": [ "thyroid mimic (discussed)", "fat loss (discussed)", "metabolic rate (discussed)", "thyroid suppression (watch-for)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "sobetriome", "gc1 thyroid", "qrx431", "gc 1 sobetirome", "flat energy", "low drive", "low thyroid crash", "thyroid fog" ], "feel_search": [ "flat energy", "low drive", "low thyroid crash", "thyroid fog" ], "summary": "People discuss GC-1 for thyroid-like fat loss with fewer T3 tradeoffs; suppression and flat-energy claims complicate\u2026", "search_blob": "gc-1 (sobetirome) gc-1-sobetirome sobetirome gc-1 gc1 gc 1 qrx-431 qrx 431 sobetriome gc1 thyroid qrx431 gc 1 sobetirome flat energy low drive low thyroid crash thyroid fog thyroid mimic (discussed) fat loss (discussed) metabolic rate (discussed) thyroid suppression (watch-for) flat energy low drive low thyroid crash thyroid fog people discuss gc-1 for thyroid-like fat loss with fewer t3 tradeoffs; suppression and flat-energy claims complicate\u2026 people discuss gc-1 for thyroid-like fat loss with fewer t3 tradeoffs; suppression and flat-energy claims complicate that pitch. mitochondrial & metabolic compounds non-peptide systemic a thyroid mimic discussed for metabolic effects and thyroid feedback tradeoffs. systemic whole-body circulating", "legal_class": null }, { "id": 348, "slug": "hbt1", "name": "HBT1", "aliases": [ "HBT-1", "HBT 1" ], "type": "Non-peptide", "category": "Cognitive research compounds", "goals_use_cases": [ "cognition", "memory", "brain fog", "AMPA modulation" ], "delivery_methods": [ "nasal", "oral", "sublingual" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "hbt1", "hbt-1", "hbt 1", "AMPA potentiator", "brain fog", "memory", "visual clarity", "clearer thinking", "no effect" ], "feel_search": [ "brain fog", "clearer thinking", "visual clarity", "memory", "no effect" ], "summary": "People discuss memory and clearer perception, with conflicting individual reports.", "search_blob": "hbt1 hbt1 hbt-1 hbt 1 hbt1 hbt-1 hbt 1 ampa potentiator brain fog memory visual clarity clearer thinking no effect cognition memory brain fog ampa modulation brain fog clearer thinking visual clarity memory no effect people discuss memory and clearer perception, with conflicting individual reports. people discuss memory and clearer perception, with conflicting individual reports. reported routes and amounts do not establish an effective or safe regimen. cognitive research compounds non-peptide systemic discussed for brain-function effects; this label does not establish how it is absorbed. systemic whole-body circulating", "legal_class": null }, { "id": 349, "slug": "indolepropionamide", "name": "Indolepropionamide", "aliases": [ "Indole-3-propionamide", "IPAM (Indolepropionamide)" ], "type": "Non-peptide", "category": "Mitochondrial & metabolic compounds", "goals_use_cases": [ "energy (reported)", "endurance (reported)", "cognition discussion", "longevity discussion" ], "delivery_methods": [ "oral", "sublingual" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "indolepropionamide", "indole-3-propionamide", "indole propionamide", "IPAM", "energy", "endurance", "no cognitive effect" ], "feel_search": [], "summary": "IPAM means indole-3-propionamide here; distinguish it from Ipamorelin and indole-3-propionic acid.", "search_blob": "indolepropionamide indolepropionamide indole-3-propionamide ipam (indolepropionamide) indolepropionamide indole-3-propionamide indole propionamide ipam energy endurance no cognitive effect energy (reported) endurance (reported) cognition discussion longevity discussion ipam means indole-3-propionamide here; distinguish it from ipamorelin and indole-3-propionic acid. mitochondrial & metabolic compounds non-peptide systemic discussed for whole-body energy and endurance, with mixed subjective results. systemic whole-body circulating", "legal_class": null }, { "id": 350, "slug": "hydrafinil", "name": "Hydrafinil", "aliases": [ "Fluorenol", "9-Fluorenol", "Fluoren-9-ol", "9H-Fluoren-9-ol", "9-Hydroxyfluorene" ], "type": "Non-peptide", "category": "Wakefulness agents in productivity discourse", "goals_use_cases": [ "wakefulness", "focus (discussed)", "productivity (discussed)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "hydrafanil", "hidrafinil", "fluorenol", "9 fluorenol", "fluoren-9-ol", "grogginess", "wakefulness", "headache", "itching", "insomnia", "paranoia", "underwhelming" ], "feel_search": [ "grogginess", "wakefulness", "headache", "itching", "insomnia", "paranoia", "underwhelming" ], "summary": "Some people describe a short lift in alertness; others feel little or stop because of unwanted effects.", "search_blob": "hydrafinil hydrafinil fluorenol 9-fluorenol fluoren-9-ol 9h-fluoren-9-ol 9-hydroxyfluorene hydrafanil hidrafinil fluorenol 9 fluorenol fluoren-9-ol grogginess wakefulness headache itching insomnia paranoia underwhelming wakefulness focus (discussed) productivity (discussed) grogginess wakefulness headache itching insomnia paranoia underwhelming some people describe a short lift in alertness; others feel little or stop because of unwanted effects. some people describe a short lift in alertness; others feel little or stop because of unwanted effects. wakefulness agents in productivity discourse non-peptide systemic oral reports concern alertness rather than a local treatment site. systemic whole-body circulating", "legal_class": null }, { "id": 351, "slug": "isrib", "name": "ISRIB", "aliases": [ "trans-ISRIB", "ISRIB-A1", "Integrated stress response inhibitor" ], "type": "Non-peptide", "category": "Cognitive research compounds", "goals_use_cases": [ "cognition", "memory discussion", "brain fog", "stress-related cognitive symptoms", "longevity research discussion" ], "delivery_methods": [ "oral", "sublingual (reported)", "nasal" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "isrib", "trans isrib", "ISRIB A1", "integrated stress response inhibitor", "eIF2B", "brain fog", "mental friction", "ISRIB-A15 comparison", "mental clarity", "rumination", "procrastination", "fatigue", "sleepiness", "emotional blunting" ], "feel_search": [ "brain fog", "mental clarity", "rumination", "procrastination", "fatigue", "sleepiness", "emotional blunting" ], "summary": "People describe less mental friction or clearer thinking, but reports also include mild change, fatigue and no relief.", "search_blob": "isrib isrib trans-isrib isrib-a1 integrated stress response inhibitor isrib trans isrib isrib a1 integrated stress response inhibitor eif2b brain fog mental friction isrib-a15 comparison mental clarity rumination procrastination fatigue sleepiness emotional blunting cognition memory discussion brain fog stress-related cognitive symptoms longevity research discussion brain fog mental clarity rumination procrastination fatigue sleepiness emotional blunting people describe less mental friction or clearer thinking, but reports also include mild change, fatigue and no relief. people describe less mental friction or clearer thinking, but reports also include mild change, fatigue and no relief. cognitive research compounds non-peptide systemic people discuss brain-wide cognitive changes; human exposure from reported oral and other routes is uncertain. systemic whole-body circulating", "legal_class": null }, { "id": 352, "slug": "itpp", "name": "ITPP", "aliases": [ "Myo-inositol trispyrophosphate", "Inositol trispyrophosphate", "Myo-inositol trispyrophosphate hexasodium salt", "ITPP hexasodium salt" ], "type": "Non-peptide", "category": "Performance / endurance", "goals_use_cases": [ "endurance", "performance", "fatigue (discussed)", "exercise tolerance (discussed)" ], "delivery_methods": [ "oral", "sublingual", "intramuscular" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "ITTP", "inositol tripyrophosphate", "inositol trispirophosphate", "ITPP endurance", "oxygen delivery", "catching breath", "stamina", "endurance", "exercise fatigue", "brain fog", "headache", "breathing difficulty" ], "feel_search": [ "stamina", "endurance", "exercise fatigue", "brain fog", "headache", "breathing difficulty" ], "summary": "People discuss easier sustained exercise, but accounts also include nonresponse and adverse symptoms.", "search_blob": "itpp itpp myo-inositol trispyrophosphate inositol trispyrophosphate myo-inositol trispyrophosphate hexasodium salt itpp hexasodium salt ittp inositol tripyrophosphate inositol trispirophosphate itpp endurance oxygen delivery catching breath stamina endurance exercise fatigue brain fog headache breathing difficulty endurance performance fatigue (discussed) exercise tolerance (discussed) stamina endurance exercise fatigue brain fog headache breathing difficulty people discuss easier sustained exercise, but accounts also include nonresponse and adverse symptoms. people discuss easier sustained exercise, but accounts also include nonresponse and adverse symptoms. performance / endurance non-peptide systemic people describe whole-body stamina effects, with mixed results and unresolved product identity. systemic whole-body circulating", "legal_class": null }, { "id": 353, "slug": "l-tetrahydropalmatine", "name": "L-Tetrahydropalmatine", "aliases": [ "L-THP", "Levo-tetrahydropalmatine", "Levotetrahydropalmatine", "l-tetrahydropalmatine" ], "type": "Non-peptide", "category": "Sleep / mood", "goals_use_cases": [ "sleep", "sleep onset (discussed)", "sedation (reported)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "l thp", "l-thp", "l tetrahydropalmatine", "tetrahydropalmatine", "Rotunda", "rotundine", "Corydalis alkaloid", "sleep onset", "morning sedation", "grogginess", "emotional flatness", "panic-like reaction" ], "feel_search": [ "sleep onset", "morning sedation", "grogginess", "emotional flatness", "panic-like reaction" ], "summary": "People describe easier sleep or strong sedation, with nonresponse and unwanted effects too.", "search_blob": "l-tetrahydropalmatine l-tetrahydropalmatine l-thp levo-tetrahydropalmatine levotetrahydropalmatine l-tetrahydropalmatine l thp l-thp l tetrahydropalmatine tetrahydropalmatine rotunda rotundine corydalis alkaloid sleep onset morning sedation grogginess emotional flatness panic-like reaction sleep sleep onset (discussed) sedation (reported) sleep onset morning sedation grogginess emotional flatness panic-like reaction people describe easier sleep or strong sedation, with nonresponse and unwanted effects too. people describe easier sleep or strong sedation, with nonresponse and unwanted effects too. sleep / mood non-peptide systemic a plant-derived compound discussed for sleep and sedation. systemic whole-body circulating", "legal_class": null }, { "id": 354, "slug": "dehydroxyfluorafinil", "name": "Dehydroxyfluorafinil", "aliases": [ "Modafiendz", "Fiendz", "N-methyl-4,4-difluoromodafinil", "N-methylbisfluoromodafinil" ], "type": "Non-peptide", "category": "Wakefulness agents in productivity discourse", "goals_use_cases": [ "focus (discussed)", "wakefulness", "productivity (discussed)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "modafiendz", "modafienz", "fiendz", "dehydroxyfluorafinil", "n methyl bisfluoro modafinil", "alertness", "focus", "sleepiness", "palpitations", "unpleasant stimulation" ], "feel_search": [ "alertness", "focus", "sleepiness", "palpitations", "unpleasant stimulation" ], "summary": "Dehydroxyfluorafinil, often called Modafiendz, attracts interest as a modafinil-related wakefulness compound.", "search_blob": "dehydroxyfluorafinil dehydroxyfluorafinil modafiendz fiendz n-methyl-4,4-difluoromodafinil n-methylbisfluoromodafinil modafiendz modafienz fiendz dehydroxyfluorafinil n methyl bisfluoro modafinil alertness focus sleepiness palpitations unpleasant stimulation focus (discussed) wakefulness productivity (discussed) alertness focus sleepiness palpitations unpleasant stimulation dehydroxyfluorafinil, often called modafiendz, attracts interest as a modafinil-related wakefulness compound. dehydroxyfluorafinil, often called modafiendz, attracts interest as a modafinil-related wakefulness compound. reports include no benefit, unpleasant stimulation and palpitations. wakefulness agents in productivity discourse non-peptide systemic people discuss whole-body alertness, focus and unwanted stimulation. systemic whole-body circulating", "legal_class": null }, { "id": 355, "slug": "n-methyl-cyclazodone", "name": "N-methyl cyclazodone", "aliases": [ "N-methylcyclazodone", "N-methyl-cyclazodone", "NMC" ], "type": "Non-peptide", "category": "Cognitive research compounds", "goals_use_cases": [ "wakefulness", "energy", "focus", "motivation" ], "delivery_methods": [ "oral", "sublingual", "nasal" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "n methyl cyclazodone", "n-methylcyclazodone", "n methyl cyclozadone", "NMC", "long stimulation", "brain fog", "wakefulness", "headache", "focus", "anxiety" ], "feel_search": [ "wakefulness", "focus", "brain fog", "headache", "anxiety", "long stimulation" ], "summary": "N-methyl cyclazodone (NMC) is a research stimulant discussed for wakefulness, motivation and getting work done.\u2026", "search_blob": "n-methyl cyclazodone n-methyl-cyclazodone n-methylcyclazodone n-methyl-cyclazodone nmc n methyl cyclazodone n-methylcyclazodone n methyl cyclozadone nmc long stimulation brain fog wakefulness headache focus anxiety wakefulness energy focus motivation wakefulness focus brain fog headache anxiety long stimulation n-methyl cyclazodone (nmc) is a research stimulant discussed for wakefulness, motivation and getting work done.\u2026 n-methyl cyclazodone (nmc) is a research stimulant discussed for wakefulness, motivation and getting work done. reports include useful alertness, little benefit and stimulation that outlasts useful concentration. it is distinct from cyclazodone; their doses and timelines cannot be substituted. cognitive research compounds non-peptide systemic whole-body stimulation and wakefulness, with variable concentration and sleep effects. systemic whole-body circulating", "legal_class": null }, { "id": 356, "slug": "nefiracetam", "name": "Nefiracetam", "aliases": [ "DM-9384", "DM9384", "DZL-221", "DM 9384" ], "type": "Non-peptide", "category": "Cognitive research compounds", "goals_use_cases": [ "cognition", "mood", "brain fog", "apathy", "memory / recall", "apathy / motivation discussion" ], "delivery_methods": [ "oral", "sublingual" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "nefiracetam", "nefitacetam", "nefi", "DM-9384", "DM9384", "DZL-221", "brain fog", "apathy", "stable mood", "verbal fluency", "calm focus", "recall", "word finding", "sluggishness" ], "feel_search": [ "calm focus", "brain fog", "apathy", "recall", "word finding", "stable mood", "sluggishness" ], "summary": "People discuss Nefiracetam for steady mood, clearer thinking and recall; effects can be subtle or absent.", "search_blob": "nefiracetam nefiracetam dm-9384 dm9384 dzl-221 dm 9384 nefiracetam nefitacetam nefi dm-9384 dm9384 dzl-221 brain fog apathy stable mood verbal fluency calm focus recall word finding sluggishness cognition mood brain fog apathy memory / recall apathy / motivation discussion calm focus brain fog apathy recall word finding stable mood sluggishness people discuss nefiracetam for steady mood, clearer thinking and recall; effects can be subtle or absent. people discuss nefiracetam for steady mood, clearer thinking and recall; effects can be subtle or absent. nausea, headaches and low mood after stopping appear in reports; animal safety signals need context. cognitive research compounds non-peptide systemic a racetam discussed for mood, mental clarity and memory. systemic whole-body circulating", "legal_class": null }, { "id": 357, "slug": "nooglutyl", "name": "Nooglutyl", "aliases": [ "Nooglutil", "ONK-10", "N-(5-hydroxynicotinoyl)-L-glutamic acid", "N-(5-oxynicotinoyl)-L-glutamic acid" ], "type": "Non-peptide", "category": "Cognitive research compounds", "goals_use_cases": [ "cognition", "focus / attention", "memory / learning discussion", "study / work concentration" ], "delivery_methods": [ "sublingual" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "nooglutyl", "nooglutil", "noogutyl", "onk-10", "memory", "concentration", "mental clarity", "fatigue", "anxiety" ], "feel_search": [ "mental clarity", "concentration", "memory", "fatigue", "anxiety" ], "summary": "People describe brief concentration or memory benefits, with fatigue and sleep costs.", "search_blob": "nooglutyl nooglutyl nooglutil onk-10 n-(5-hydroxynicotinoyl)-l-glutamic acid n-(5-oxynicotinoyl)-l-glutamic acid nooglutyl nooglutil noogutyl onk-10 memory concentration mental clarity fatigue anxiety cognition focus / attention memory / learning discussion study / work concentration mental clarity concentration memory fatigue anxiety people describe brief concentration or memory benefits, with fatigue and sleep costs. people describe brief concentration or memory benefits, with fatigue and sleep costs. cognitive research compounds non-peptide systemic discussion concerns brain effects; the detailed powder review begins with sublingual use. systemic whole-body circulating", "legal_class": null }, { "id": 358, "slug": "nsi-189", "name": "NSI-189", "aliases": [ "NSI 189", "NSI189", "NSI-189 phosphate", "NSI-189 freebase", "ALTO-100", "ALTO 100", "Amdiglurax" ], "type": "Non-peptide", "category": "Cognitive research compounds", "goals_use_cases": [ "mood", "anhedonia discussion", "emotional responsiveness", "cognition", "memory" ], "delivery_methods": [ "oral", "sublingual" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "nsi189", "nsi 189", "nsi-189 phosphate", "nsi-189 free base", "alto100", "amdiglurax", "emotional numbness", "anhedonia", "brain fog", "emotional blunting", "music appreciation", "anxiety", "memory", "fatigue" ], "feel_search": [ "emotional numbness", "anhedonia", "brain fog", "emotional blunting", "music appreciation", "anxiety", "memory", "fatigue" ], "summary": "People discuss getting emotional responsiveness and interest back, with mixed cognitive and mood reports.", "search_blob": "nsi-189 nsi-189 nsi 189 nsi189 nsi-189 phosphate nsi-189 freebase alto-100 alto 100 amdiglurax nsi189 nsi 189 nsi-189 phosphate nsi-189 free base alto100 amdiglurax emotional numbness anhedonia brain fog emotional blunting music appreciation anxiety memory fatigue mood anhedonia discussion emotional responsiveness cognition memory emotional numbness anhedonia brain fog emotional blunting music appreciation anxiety memory fatigue people discuss getting emotional responsiveness and interest back, with mixed cognitive and mood reports. people discuss getting emotional responsiveness and interest back, with mixed cognitive and mood reports. cognitive research compounds non-peptide systemic whole-body exposure, discussed for emotional responsiveness and thinking. systemic whole-body circulating", "legal_class": null }, { "id": 359, "slug": "oxiracetam", "name": "Oxiracetam", "aliases": [ "ISF 2522", "ISF-2522" ], "type": "Non-peptide", "category": "Cognitive research compounds", "goals_use_cases": [ "cognition", "focus", "study / learning (discussed)", "morning grogginess (discussed)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "oxiracetam", "oxi", "oxiracitam", "ISF 2522", "brain fog", "study focus", "math", "grogginess", "racetam headache", "subtle focus", "mental clarity", "tired", "jittery", "music detail", "nonresponse" ], "feel_search": [ "subtle focus", "mental clarity", "tired", "jittery", "music detail", "nonresponse" ], "summary": "Oxiracetam is a racetam nootropic people discuss for studying, clearer thinking and mild stimulation. Some describe\u2026", "search_blob": "oxiracetam oxiracetam isf 2522 isf-2522 oxiracetam oxi oxiracitam isf 2522 brain fog study focus math grogginess racetam headache subtle focus mental clarity tired jittery music detail nonresponse cognition focus study / learning (discussed) morning grogginess (discussed) subtle focus mental clarity tired jittery music detail nonresponse oxiracetam is a racetam nootropic people discuss for studying, clearer thinking and mild stimulation. some describe\u2026 oxiracetam is a racetam nootropic people discuss for studying, clearer thinking and mild stimulation. some describe easier concentration or less morning grogginess; others notice little, become tired or feel overstimulated. the disagreement includes how much people take, whether choline helps, and whether an early benefit lasts. cognitive research compounds non-peptide systemic discussed for attention and alertness rather than a local application. systemic whole-body circulating", "legal_class": null }, { "id": 360, "slug": "phenibut", "name": "Phenibut", "aliases": [ "Fenibut", "Phenyl-GABA", "\u03b2-phenyl-\u03b3-aminobutyric acid", "4-Amino-3-phenylbutanoic acid", "Phenibut HCl", "Phenibut FAA", "Noofen", "Anvifen" ], "type": "Non-peptide", "category": "Cognitive research compounds", "goals_use_cases": [ "social anxiety discussion", "calm", "sociability", "mood", "sleep" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "phenibut", "fenibut", "phenyl gaba", "phenibut hcl", "phenibut faa", "noofen", "anvifen", "social anxiety", "rebound anxiety", "withdrawal", "afterglow", "tolerance", "dependence", "calm", "social confidence", "insomnia", "low mood", "sleepiness" ], "feel_search": [ "social anxiety", "calm", "social confidence", "rebound anxiety", "insomnia", "low mood", "afterglow", "sleepiness" ], "summary": "People describe easier conversation and less social anxiety; others feel little benefit or worse anxiety afterward.", "search_blob": "phenibut phenibut fenibut phenyl-gaba \u03b2-phenyl-\u03b3-aminobutyric acid 4-amino-3-phenylbutanoic acid phenibut hcl phenibut faa noofen anvifen phenibut fenibut phenyl gaba phenibut hcl phenibut faa noofen anvifen social anxiety rebound anxiety withdrawal afterglow tolerance dependence calm social confidence insomnia low mood sleepiness social anxiety discussion calm sociability mood sleep social anxiety calm social confidence rebound anxiety insomnia low mood afterglow sleepiness people describe easier conversation and less social anxiety; others feel little benefit or worse anxiety afterward. people describe easier conversation and less social anxiety; others feel little benefit or worse anxiety afterward. tolerance, dependence, withdrawal and dangerous sedation are material risks. cognitive research compounds non-peptide systemic whole-body psychoactive effects are discussed; social ease and sedation can overlap. systemic whole-body circulating", "legal_class": null }, { "id": 361, "slug": "phenylpiracetam-hydrazide", "name": "Phenylpiracetam hydrazide", "aliases": [ "PP hydrazide" ], "type": "Non-peptide", "category": "Cognitive research compounds", "goals_use_cases": [ "energy (discussed)", "mental clarity (discussed)", "focus (discussed)", "mood (discussed)" ], "delivery_methods": [ "oral", "nasal" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "phenylpiracetam hydrazide", "phenyl piracetam hydrazide", "PP hydrazide", "clear mind", "mental energy", "physical energy", "brain fog", "less speedy", "tolerance", "stomach discomfort" ], "feel_search": [ "clear mind", "mental energy", "physical energy", "brain fog", "less speedy", "tolerance", "stomach discomfort" ], "summary": "People describe energy or mental clarity, but others report fogginess, no effect or fading benefit.", "search_blob": "phenylpiracetam hydrazide phenylpiracetam-hydrazide pp hydrazide phenylpiracetam hydrazide phenyl piracetam hydrazide pp hydrazide clear mind mental energy physical energy brain fog less speedy tolerance stomach discomfort energy (discussed) mental clarity (discussed) focus (discussed) mood (discussed) clear mind mental energy physical energy brain fog less speedy tolerance stomach discomfort people describe energy or mental clarity, but others report fogginess, no effect or fading benefit. people describe energy or mental clarity, but others report fogginess, no effect or fading benefit. a separate compound from phenylpiracetam; comparative potency and human half-life remain unresolved. cognitive research compounds non-peptide systemic people discuss whole-body energy and mental clarity, not a local treatment. systemic whole-body circulating", "legal_class": null }, { "id": 362, "slug": "piracetam", "name": "Piracetam", "aliases": [ "Nootropil", "Nootropyl", "2-oxo-1-pyrrolidineacetamide" ], "type": "Non-peptide", "category": "Cognitive research compounds", "goals_use_cases": [ "memory / recall (discussed)", "focus / attention", "verbal fluency / word-finding", "mental clarity / brain fog", "social ease (reported)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "piracetam", "piracetem", "nootropil", "nootropyl", "racetam", "word finding", "brain fog", "verbal fluency", "memory", "focus", "social ease" ], "feel_search": [ "brain fog", "word finding", "memory", "focus", "social ease" ], "summary": "Piracetam is a racetam nootropic people discuss for easier recall, clearer thinking and smoother conversation. Some\u2026", "search_blob": "piracetam piracetam nootropil nootropyl 2-oxo-1-pyrrolidineacetamide piracetam piracetem nootropil nootropyl racetam word finding brain fog verbal fluency memory focus social ease memory / recall (discussed) focus / attention verbal fluency / word-finding mental clarity / brain fog social ease (reported) brain fog word finding memory focus social ease piracetam is a racetam nootropic people discuss for easier recall, clearer thinking and smoother conversation. some\u2026 piracetam is a racetam nootropic people discuss for easier recall, clearer thinking and smoother conversation. some describe a subtle useful change; others get headaches, irritability or no noticeable benefit. feeling sharper is not proof of improved learning or safety. reported benefits and adverse responses vary; co-use often clouds attribution. cognitive research compounds non-peptide systemic whole-body exposure; discussion centers on thinking and conversation. systemic whole-body circulating", "legal_class": null }, { "id": 363, "slug": "ppap", "name": "PPAP", "aliases": [ "Phenylpropylaminopentane", "PPAP HCl", "PPAP hydrochloride", "1-phenyl-2-propylaminopentane", "1-phenyl-N-propylpentan-2-amine" ], "type": "Non-peptide", "category": "Cognitive / nootropic peptides", "goals_use_cases": [ "energy", "motivation", "focus", "mood" ], "delivery_methods": [ "oral", "sublingual" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "ppap hcl", "phenylpropylaminopentane", "phenyl propyl amino pentane", "motivation", "mental energy", "no effect", "anxiety", "tolerance", "crash" ], "feel_search": [ "motivation", "mental energy", "no effect", "anxiety", "tolerance", "crash" ], "summary": "People describe wakefulness and engagement, but also no effect, anxiety and fading benefits.", "search_blob": "ppap ppap phenylpropylaminopentane ppap hcl ppap hydrochloride 1-phenyl-2-propylaminopentane 1-phenyl-n-propylpentan-2-amine ppap hcl phenylpropylaminopentane phenyl propyl amino pentane motivation mental energy no effect anxiety tolerance crash energy motivation focus mood motivation mental energy no effect anxiety tolerance crash people describe wakefulness and engagement, but also no effect, anxiety and fading benefits. people describe wakefulness and engagement, but also no effect, anxiety and fading benefits. cognitive / nootropic peptides non-peptide systemic people discuss whole-body wakefulness and mental effects. systemic whole-body circulating", "legal_class": null }, { "id": 364, "slug": "pramiracetam", "name": "Pramiracetam", "aliases": [ "Pramistar", "CI-879" ], "type": "Non-peptide", "category": "Cognitive research compounds", "goals_use_cases": [ "focus / attention", "study / productivity (discussed)", "memory / learning (discussed)", "verbal fluency (reported)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "pramiracetam", "pramiracitam", "pramistar", "CI 879", "racetam focus", "pramiracetam emotional numbness", "task focus", "brain fog", "word finding", "emotional dullness", "sleepiness", "no effect" ], "feel_search": [ "task focus", "brain fog", "word finding", "emotional dullness", "sleepiness", "no effect" ], "summary": "Some people describe calmer task focus or easier word-finding; others feel dull, sleepy or unchanged.", "search_blob": "pramiracetam pramiracetam pramistar ci-879 pramiracetam pramiracitam pramistar ci 879 racetam focus pramiracetam emotional numbness task focus brain fog word finding emotional dullness sleepiness no effect focus / attention study / productivity (discussed) memory / learning (discussed) verbal fluency (reported) task focus brain fog word finding emotional dullness sleepiness no effect some people describe calmer task focus or easier word-finding; others feel dull, sleepy or unchanged. some people describe calmer task focus or easier word-finding; others feel dull, sleepy or unchanged. caffeine and other co-use complicate the clearest productivity accounts. cognitive research compounds non-peptide systemic an oral compound with whole-body exposure; discussion centers on focus and memory. systemic whole-body circulating", "legal_class": null }, { "id": 365, "slug": "prl-8-53", "name": "PRL-8-53", "aliases": [ "PRL 8-53", "PRL853", "PRL 8 53", "3-(2-benzylmethylaminoethyl) benzoic acid methyl ester hydrochloride" ], "type": "Non-peptide", "category": "Cognitive research compounds", "goals_use_cases": [ "memory / learning (discussed)", "verbal recall", "study retention", "language learning" ], "delivery_methods": [ "oral", "sublingual" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "prl853", "prl 8 53", "prl 8-53", "prl-8-53", "word recall", "remember vocabulary", "study retention", "working memory", "brain fog" ], "feel_search": [ "word recall", "remember vocabulary", "study retention", "working memory", "brain fog" ], "summary": "People discuss PRL-8-53 for easier recall of vocabulary and study material.", "search_blob": "prl-8-53 prl-8-53 prl 8-53 prl853 prl 8 53 3-(2-benzylmethylaminoethyl) benzoic acid methyl ester hydrochloride prl853 prl 8 53 prl 8-53 prl-8-53 word recall remember vocabulary study retention working memory brain fog memory / learning (discussed) verbal recall study retention language learning word recall remember vocabulary study retention working memory brain fog people discuss prl-8-53 for easier recall of vocabulary and study material. people discuss prl-8-53 for easier recall of vocabulary and study material. reports include unchanged memory and adverse effects; stimulant co-use complicates prominent success stories. cognitive research compounds non-peptide systemic discussed for recall and learning through oral and sublingual use. systemic whole-body circulating", "legal_class": null }, { "id": 366, "slug": "rgpu-95", "name": "RGPU-95", "aliases": [ "p-Cl-Phenylpiracetam", "p-Chlorophenylpiracetam", "para-Chlorophenylpiracetam", "4-Chlorophenylpiracetam", "RGPU 95" ], "type": "Non-peptide", "category": "Cognitive research compounds", "goals_use_cases": [ "focus", "mood", "anxiety (discussed)", "energy (discussed)" ], "delivery_methods": [ "sublingual" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "RGPU95", "RPGU 95", "p-cl phenylpiracetam", "calmer focus", "anxiety relief", "flat mood", "emotional flattening", "low energy", "mental clarity" ], "feel_search": [ "calmer focus", "anxiety relief", "flat mood", "emotional flattening", "low energy", "mental clarity" ], "summary": "Some report calmer focus; others describe flat mood, less energy or little effect.", "search_blob": "rgpu-95 rgpu-95 p-cl-phenylpiracetam p-chlorophenylpiracetam para-chlorophenylpiracetam 4-chlorophenylpiracetam rgpu 95 rgpu95 rpgu 95 p-cl phenylpiracetam calmer focus anxiety relief flat mood emotional flattening low energy mental clarity focus mood anxiety (discussed) energy (discussed) calmer focus anxiety relief flat mood emotional flattening low energy mental clarity some report calmer focus; others describe flat mood, less energy or little effect. some report calmer focus; others describe flat mood, less energy or little effect. cognitive research compounds non-peptide systemic people discuss changes in calm, focus, mood and energy. systemic whole-body circulating", "legal_class": null }, { "id": 367, "slug": "roxadustat", "name": "Roxadustat", "aliases": [ "FG-4592", "FG4592", "FG 4592", "Evrenzo", "Roxa" ], "type": "Non-peptide", "category": "Performance / endurance", "goals_use_cases": [ "endurance (discussed)", "hematocrit (discussed)", "cognitive clarity (anecdotal)", "CKD anemia (medical context)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "roxadustat", "roxudustat", "FG-4592", "FG4592", "FG 4592", "Evrenzo", "Roxa", "hematocrit", "endurance", "clear headed", "cardio", "nonresponse" ], "feel_search": [ "endurance", "cardio", "clear headed", "nonresponse" ], "summary": "Roxadustat is an oral anemia drug discussed by biohackers for endurance and clearer thinking. The most useful training\u2026", "search_blob": "roxadustat roxadustat fg-4592 fg4592 fg 4592 evrenzo roxa roxadustat roxudustat fg-4592 fg4592 fg 4592 evrenzo roxa hematocrit endurance clear headed cardio nonresponse endurance (discussed) hematocrit (discussed) cognitive clarity (anecdotal) ckd anemia (medical context) endurance cardio clear headed nonresponse roxadustat is an oral anemia drug discussed by biohackers for endurance and clearer thinking. the most useful training\u2026 roxadustat is an oral anemia drug discussed by biohackers for endurance and clearer thinking. the most useful training log starts with no blood-count change after two weeks, then reports a later hematocrit rise; another person describes better cardio and clarity. these accounts do not establish a dependable performance or cognitive benefit. performance / endurance non-peptide systemic discussed for whole-body blood and performance effects. systemic whole-body circulating", "legal_class": null }, { "id": 368, "slug": "sana-mvd1", "name": "SANA (MVD1)", "aliases": [ "SANA", "MVD1", "SANA MVD1", "5-(2-nitroethenyl)salicylic acid", "2-Hydroxy-5-(2-nitroethenyl)benzoic acid" ], "type": "Non-peptide", "category": "Metabolic research compounds", "goals_use_cases": [ "fat loss discussion", "thermogenesis", "metabolic health discussion" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "sana", "mvd1", "sana mvd1", "salicylate nitroalkene", "warmth", "appetite preserved", "lethargy", "no noticeable effect" ], "feel_search": [ "warmth", "appetite preserved", "lethargy", "no noticeable effect" ], "summary": "SANA is discussed for weight loss while keeping an appetite; direct experience remains limited.", "search_blob": "sana (mvd1) sana-mvd1 sana mvd1 sana mvd1 5-(2-nitroethenyl)salicylic acid 2-hydroxy-5-(2-nitroethenyl)benzoic acid sana mvd1 sana mvd1 salicylate nitroalkene warmth appetite preserved lethargy no noticeable effect fat loss discussion thermogenesis metabolic health discussion warmth appetite preserved lethargy no noticeable effect sana is discussed for weight loss while keeping an appetite; direct experience remains limited. sana is discussed for weight loss while keeping an appetite; direct experience remains limited. the strongest personal weight claim includes bam15, and the early human study includes kidney injury. metabolic research compounds non-peptide systemic discussed for whole-body weight and energy use, not site-specific fat loss. systemic whole-body circulating", "legal_class": null }, { "id": 369, "slug": "sm04554", "name": "SM04554", "aliases": [ "SM-04554", "SM 04554", "Dalosirvat" ], "type": "Non-peptide", "category": "Skin, hair & tissue remodeling", "goals_use_cases": [ "androgenetic alopecia pipeline", "hair regrowth discussion", "Wnt pathway discussion" ], "delivery_methods": [ "topical" ], "discussion_popularity": "Emerging", "reach": "Local", "misspellings_search_terms": [ "sm04554", "sm-04554", "sm 04554", "dalosirvat", "samumed hair", "biosplice hair", "wnt hair", "thinning hair", "hair density", "permanent regrowth", "dormant follicles" ], "feel_search": [ "thinning hair", "hair density", "permanent regrowth", "dormant follicles" ], "summary": "An experimental scalp compound followed for hair regrowth, with hopes that outpaced verified participant outcomes.", "search_blob": "sm04554 sm04554 sm-04554 sm 04554 dalosirvat sm04554 sm-04554 sm 04554 dalosirvat samumed hair biosplice hair wnt hair thinning hair hair density permanent regrowth dormant follicles androgenetic alopecia pipeline hair regrowth discussion wnt pathway discussion thinning hair hair density permanent regrowth dormant follicles an experimental scalp compound followed for hair regrowth, with hopes that outpaced verified participant outcomes. an experimental scalp compound followed for hair regrowth, with hopes that outpaced verified participant outcomes. historical trial discussion does not establish a current consumer treatment. skin, hair & tissue remodeling non-peptide local studied as a solution applied to the scalp. local site pin topical", "legal_class": null }, { "id": 370, "slug": "sunifiram", "name": "Sunifiram", "aliases": [ "DM235", "DM-235", "DM 235" ], "type": "Non-peptide", "category": "Cognitive research compounds", "goals_use_cases": [ "cognition", "focus", "memory / learning discussion", "mood", "sensory vividness" ], "delivery_methods": [ "oral", "sublingual" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "sunifiram", "sunifram", "DM235", "DM-235", "DM 235", "brain fog", "focus", "recall", "music", "irritability", "headache", "sound sensitivity" ], "feel_search": [ "brain fog", "focus", "recall", "music", "irritability", "headache", "sound sensitivity" ], "summary": "People discuss recall, focus, mood and sensory vividness, with mixed results.", "search_blob": "sunifiram sunifiram dm235 dm-235 dm 235 sunifiram sunifram dm235 dm-235 dm 235 brain fog focus recall music irritability headache sound sensitivity cognition focus memory / learning discussion mood sensory vividness brain fog focus recall music irritability headache sound sensitivity people discuss recall, focus, mood and sensory vividness, with mixed results. people discuss recall, focus, mood and sensory vividness, with mixed results. early gains can give way to fog, sleep problems or irritation. cognitive research compounds non-peptide systemic people discuss swallowed and under-the-tongue use for cognitive effects. systemic whole-body circulating", "legal_class": null }, { "id": 371, "slug": "thozalinone", "name": "Thozalinone", "aliases": [ "Tozalinone", "CL-39808", "CL 39808", "Stimsen" ], "type": "Non-peptide", "category": "Wakefulness agents in productivity discourse", "goals_use_cases": [ "focus (discussed)", "wakefulness", "mood (discussed)" ], "delivery_methods": [ "oral", "nasal", "rectal" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "thozalinon", "thozaline", "tozalinone", "CL39808", "Stimsen", "thozalinone focus", "thozalinone no effect", "quiet energy", "weak stimulant", "no effect", "distracting euphoria", "insomnia" ], "feel_search": [ "quiet energy", "weak stimulant", "no effect", "distracting euphoria", "insomnia" ], "summary": "Some describe quiet focus or mood lift; others report little benefit or distracting euphoria.", "search_blob": "thozalinone thozalinone tozalinone cl-39808 cl 39808 stimsen thozalinon thozaline tozalinone cl39808 stimsen thozalinone focus thozalinone no effect quiet energy weak stimulant no effect distracting euphoria insomnia focus (discussed) wakefulness mood (discussed) quiet energy weak stimulant no effect distracting euphoria insomnia some describe quiet focus or mood lift; others report little benefit or distracting euphoria. some describe quiet focus or mood lift; others report little benefit or distracting euphoria. sleep effects can outlast the desired effect. wakefulness agents in productivity discourse non-peptide systemic people discuss whole-body alertness, mood and sleep effects. systemic whole-body circulating", "legal_class": null }, { "id": 372, "slug": "tropisetron", "name": "Tropisetron", "aliases": [ "Navoban", "Tropisetron hydrochloride", "Tropisetron HCl" ], "type": "Non-peptide", "category": "Cognitive research compounds", "goals_use_cases": [ "focus (discussed)", "cognition (discussed)", "calm (discussed)", "brain fog (discussed)" ], "delivery_methods": [ "oral", "IV" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "tropisetron", "tropisteron", "trop", "navoban", "tropisetron HCl", "alpha7", "5-HT3", "brain fog", "clearer thinking", "focus", "calm", "constipation", "headache" ], "feel_search": [ "brain fog", "clearer thinking", "focus", "calm", "constipation", "headache" ], "summary": "People discuss clearer thinking and calmer focus, with constipation and headaches as meaningful tradeoffs.", "search_blob": "tropisetron tropisetron navoban tropisetron hydrochloride tropisetron hcl tropisetron tropisteron trop navoban tropisetron hcl alpha7 5-ht3 brain fog clearer thinking focus calm constipation headache focus (discussed) cognition (discussed) calm (discussed) brain fog (discussed) brain fog clearer thinking focus calm constipation headache people discuss clearer thinking and calmer focus, with constipation and headaches as meaningful tradeoffs. people discuss clearer thinking and calmer focus, with constipation and headaches as meaningful tradeoffs. cognitive research compounds non-peptide systemic people discuss mental effects alongside changes in gut function. systemic whole-body circulating", "legal_class": null }, { "id": 373, "slug": "unifiram", "name": "Unifiram", "aliases": [ "DM-232", "DM232" ], "type": "Non-peptide", "category": "Cognitive research compounds", "goals_use_cases": [ "cognition", "focus", "mental clarity", "wakefulness", "mood" ], "delivery_methods": [ "oral", "sublingual", "nasal" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "unifiram", "unifram", "dm232", "dm-232", "uni nootropic", "mental clarity", "brain fog", "calm focus", "wakefulness", "racing thoughts", "sleep disruption" ], "feel_search": [ "mental clarity", "brain fog", "calm focus", "wakefulness", "racing thoughts", "sleep disruption" ], "summary": "People describe calm clarity and wakefulness, with inconsistent results and reports of fog or poor sleep.", "search_blob": "unifiram unifiram dm-232 dm232 unifiram unifram dm232 dm-232 uni nootropic mental clarity brain fog calm focus wakefulness racing thoughts sleep disruption cognition focus mental clarity wakefulness mood mental clarity brain fog calm focus wakefulness racing thoughts sleep disruption people describe calm clarity and wakefulness, with inconsistent results and reports of fog or poor sleep. people describe calm clarity and wakefulness, with inconsistent results and reports of fog or poor sleep. cognitive research compounds non-peptide systemic people discuss effects on alertness, mood and perception. systemic whole-body circulating", "legal_class": null }, { "id": 374, "slug": "mirabegron", "name": "Mirabegron (YM-178)", "aliases": [ "YM-178", "YM178", "YM 178", "Myrbetriq", "Betmiga", "Betanis" ], "type": "Non-peptide", "category": "Mitochondrial & metabolic compounds", "goals_use_cases": [ "fat loss (discussed)", "brown fat", "metabolic health", "bladder symptoms (clinical context)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "mirabegron", "mirabegon", "mirabregon", "ym178", "ym-178", "brown fat", "BAT", "nighttime urination", "sleep", "pumps", "palpitations", "dizziness", "no effect" ], "feel_search": [ "nighttime urination", "sleep", "pumps", "palpitations", "dizziness", "no effect" ], "summary": "Mirabegron and YM-178 name the same beta-3 agonist.", "search_blob": "mirabegron (ym-178) mirabegron ym-178 ym178 ym 178 myrbetriq betmiga betanis mirabegron mirabegon mirabregon ym178 ym-178 brown fat bat nighttime urination sleep pumps palpitations dizziness no effect fat loss (discussed) brown fat metabolic health bladder symptoms (clinical context) nighttime urination sleep pumps palpitations dizziness no effect mirabegron and ym-178 name the same beta-3 agonist. mitochondrial & metabolic compounds non-peptide systemic a whole-body drug discussed for brown fat and used clinically for bladder symptoms. systemic whole-body circulating", "legal_class": null }, { "id": 375, "slug": "sr9011", "name": "SR-9011", "aliases": [ "SR9011", "SR 9011" ], "type": "Non-peptide", "category": "Metabolic research compounds", "goals_use_cases": [ "endurance", "fat loss", "performance", "circadian rhythm discussion" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "sr9011", "sr-9011", "sr 9011", "REV-ERB agonist", "oral absorption", "sleep crash", "energy", "endurance", "sleepiness", "insomnia", "restless legs", "fatigue" ], "feel_search": [ "energy", "endurance", "sleepiness", "insomnia", "restless legs", "fatigue" ], "summary": "People discuss more training energy and fat loss, with mixed results and substantial sleep complaints.", "search_blob": "sr-9011 sr9011 sr9011 sr 9011 sr9011 sr-9011 sr 9011 rev-erb agonist oral absorption sleep crash energy endurance sleepiness insomnia restless legs fatigue endurance fat loss performance circadian rhythm discussion energy endurance sleepiness insomnia restless legs fatigue people discuss more training energy and fat loss, with mixed results and substantial sleep complaints. people discuss more training energy and fat loss, with mixed results and substantial sleep complaints. metabolic research compounds non-peptide systemic people discuss whole-body changes in energy, training and sleep. systemic whole-body circulating", "legal_class": null }, { "id": 376, "slug": "fluoxymesterone", "name": "Fluoxymesterone", "aliases": [ "Halotestin", "Halo", "Ora-Testryl", "Anadroid-F", "Stenox" ], "type": "Non-peptide", "category": "Hormones in performance discourse", "goals_use_cases": [ "strength", "competition drive (discussed)", "hardening (discussed)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "fluoxymesterone", "fluoximesterone", "halotestin", "halo steroid", "halotestine", "stenox", "strength", "aggression", "road rage", "hard look", "vascularity", "lethargy", "pre workout" ], "feel_search": [ "strength", "aggression", "road rage", "hard look", "vascularity", "lethargy", "pre workout" ], "summary": "People discuss strength and competitive drive, with sharply mixed responses.", "search_blob": "fluoxymesterone fluoxymesterone halotestin halo ora-testryl anadroid-f stenox fluoxymesterone fluoximesterone halotestin halo steroid halotestine stenox strength aggression road rage hard look vascularity lethargy pre workout strength competition drive (discussed) hardening (discussed) strength aggression road rage hard look vascularity lethargy pre workout people discuss strength and competitive drive, with sharply mixed responses. people discuss strength and competitive drive, with sharply mixed responses. aggression, blood pressure and liver risk can outweigh the gym effect. hormones in performance discourse non-peptide systemic an oral steroid with whole-body effects. u.s. schedule iii iii systemic whole-body circulating", "legal_class": { "schedule": "III", "label": "U.S. Schedule III" } }, { "id": 378, "slug": "hydrochlorothiazide", "name": "Hydrochlorothiazide", "aliases": [ "HCTZ", "hydrochlorothiazide (HCTZ)" ], "type": "Non-peptide", "category": "Diuretics & fluid balance", "goals_use_cases": [ "water retention discussion", "blood-pressure discussion", "bodybuilding diuretic cautions", "triamterene combination comparison" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "hctz", "hydrochlorothiazid", "hydroclorothiazide", "hydrochlorothiazide triamterene", "triamterene hctz", "triamterene", "dyazide", "maxzide", "dyazide combination", "water pill", "retained water", "electrolyte cramps", "puffy", "bloating", "water retention", "cramps", "dizziness", "flat muscles", "frequent urination", "potassium" ], "feel_search": [ "puffy", "bloating", "water retention", "cramps", "dizziness", "flat muscles", "frequent urination", "potassium" ], "summary": "People discuss HCTZ for retained water and blood pressure, with reports ranging from relief to cramps and dizziness.", "search_blob": "hydrochlorothiazide hydrochlorothiazide hctz hydrochlorothiazide (hctz) hctz hydrochlorothiazid hydroclorothiazide hydrochlorothiazide triamterene triamterene hctz triamterene dyazide maxzide dyazide combination water pill retained water electrolyte cramps puffy bloating water retention cramps dizziness flat muscles frequent urination potassium water retention discussion blood-pressure discussion bodybuilding diuretic cautions triamterene combination comparison puffy bloating water retention cramps dizziness flat muscles frequent urination potassium people discuss hctz for retained water and blood pressure, with reports ranging from relief to cramps and dizziness. people discuss hctz for retained water and blood pressure, with reports ranging from relief to cramps and dizziness. triamterene/hctz contains two drugs and can still cause dangerous electrolyte changes. diuretics & fluid balance non-peptide systemic an oral water pill affecting salt, water and electrolyte balance throughout the body. systemic whole-body circulating", "legal_class": null }, { "id": 379, "slug": "methionine", "name": "Methionine", "aliases": [ "L-methionine", "L Methionine" ], "type": "Non-peptide", "category": "Longevity & cellular energy", "goals_use_cases": [ "energy (reported)", "mood (reported)", "methylation discussion", "MIC / lipotropic ingredient context" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "methionine", "l methionine", "l-methionine", "methylation", "methionine vs SAMe", "MIC ingredient", "fatigue", "energy", "lethargy", "sleepiness", "anxiety", "no noticeable effect" ], "feel_search": [ "fatigue", "energy", "lethargy", "sleepiness", "anxiety", "no noticeable effect" ], "summary": "Methionine is an essential amino acid discussed for energy, mood and methylation, and as an ingredient in MIC blends.", "search_blob": "methionine methionine l-methionine l methionine methionine l methionine l-methionine methylation methionine vs same mic ingredient fatigue energy lethargy sleepiness anxiety no noticeable effect energy (reported) mood (reported) methylation discussion mic / lipotropic ingredient context fatigue energy lethargy sleepiness anxiety no noticeable effect methionine is an essential amino acid discussed for energy, mood and methylation, and as an ingredient in mic blends. methionine is an essential amino acid discussed for energy, mood and methylation, and as an ingredient in mic blends. longevity & cellular energy non-peptide systemic an amino acid discussed orally and as one ingredient of systemic mic blends. systemic whole-body circulating", "legal_class": null }, { "id": 380, "slug": "atp", "name": "ATP (adenosine triphosphate)", "aliases": [ "ATP", "Adenosine triphosphate", "Adenosine 5\u2032-triphosphate", "Adenosine 5-triphosphate", "ATP disodium", "PEAK ATP (branded oral disodium form)" ], "type": "Non-peptide", "category": "Performance staples (biohacking overlap)", "goals_use_cases": [ "performance", "workout capacity", "energy (reported)", "recovery after exertion (reported)" ], "delivery_methods": [ "oral", "sublingual (separate anecdotal context)" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "adenosine triphosphate", "peak atp", "oral atp", "atp supplement", "ATP crash", "workout energy", "fatigue", "post-workout crash", "stomach discomfort" ], "feel_search": [ "workout energy", "fatigue", "post-workout crash", "stomach discomfort" ], "summary": "People discuss a little more workout capacity or energy, with mixed results and some adverse experiences.", "search_blob": "atp (adenosine triphosphate) atp atp adenosine triphosphate adenosine 5\u2032-triphosphate adenosine 5-triphosphate atp disodium peak atp (branded oral disodium form) adenosine triphosphate peak atp oral atp atp supplement atp crash workout energy fatigue post-workout crash stomach discomfort performance workout capacity energy (reported) recovery after exertion (reported) workout energy fatigue post-workout crash stomach discomfort people discuss a little more workout capacity or energy, with mixed results and some adverse experiences. people discuss a little more workout capacity or energy, with mixed results and some adverse experiences. performance staples (biohacking overlap) non-peptide systemic people discuss workout capacity and general energy rather than a local treatment. systemic whole-body circulating", "legal_class": null }, { "id": 381, "slug": "dimethylglycine", "name": "Dimethylglycine", "aliases": [ "DMG", "N,N-Dimethylglycine", "N-Methylsarcosine", "2-(Dimethylamino)acetic acid" ], "type": "Non-peptide", "category": "Longevity & cellular energy", "goals_use_cases": [ "energy / fatigue discussion", "methylation", "mental clarity", "mood", "topical hair / shedding discussion" ], "delivery_methods": [ "oral", "sublingual", "topical" ], "discussion_popularity": "Emerging", "reach": "Mixed", "misspellings_search_terms": [ "dmg", "dimethyl glycine", "dimethylglycine", "N,N-dimethylglycine", "dimethylglycin", "methylation", "brain fog", "fatigue", "shampoo", "energy", "mental clarity", "subtle smile", "revved up", "hair shedding" ], "feel_search": [ "energy", "mental clarity", "brain fog", "subtle smile", "revved up", "hair shedding" ], "summary": "People discuss DMG for energy, clarity and subtle mood effects; experiences and products differ.", "search_blob": "dimethylglycine dimethylglycine dmg n,n-dimethylglycine n-methylsarcosine 2-(dimethylamino)acetic acid dmg dimethyl glycine dimethylglycine n,n-dimethylglycine dimethylglycin methylation brain fog fatigue shampoo energy mental clarity subtle smile revved up hair shedding energy / fatigue discussion methylation mental clarity mood topical hair / shedding discussion energy mental clarity brain fog subtle smile revved up hair shedding people discuss dmg for energy, clarity and subtle mood effects; experiences and products differ. people discuss dmg for energy, clarity and subtle mood effects; experiences and products differ. longevity & cellular energy non-peptide mixed supplement reports concern whole-body effects; shampoo discussion concerns the scalp. mixed local systemic", "legal_class": null }, { "id": 382, "slug": "sodium-bicarbonate", "name": "Sodium bicarbonate", "aliases": [ "Baking soda", "Bicarbonate of soda", "Sodium hydrogen carbonate", "NaHCO3", "Bicarb" ], "type": "Non-peptide", "category": "Performance staples (biohacking overlap)", "goals_use_cases": [ "performance", "high-intensity effort", "acid-buffering discussion", "running", "cycling" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "sodium bicarbonate", "baking soda", "bicarbonate of soda", "bicarb", "NaHCO3", "sodium hydrogen carbonate", "burning legs", "hard efforts feel easier", "stomach cramps", "diarrhea", "no noticeable benefit" ], "feel_search": [ "burning legs", "hard efforts feel easier", "stomach cramps", "diarrhea", "no noticeable benefit" ], "summary": "People discuss easier hard efforts, alongside no clear benefit and stomach trouble.", "search_blob": "sodium bicarbonate sodium-bicarbonate baking soda bicarbonate of soda sodium hydrogen carbonate nahco3 bicarb sodium bicarbonate baking soda bicarbonate of soda bicarb nahco3 sodium hydrogen carbonate burning legs hard efforts feel easier stomach cramps diarrhea no noticeable benefit performance high-intensity effort acid-buffering discussion running cycling burning legs hard efforts feel easier stomach cramps diarrhea no noticeable benefit people discuss easier hard efforts, alongside no clear benefit and stomach trouble. people discuss easier hard efforts, alongside no clear benefit and stomach trouble. performance staples (biohacking overlap) non-peptide systemic oral bicarbonate is discussed for whole-body acid buffering during demanding exercise. systemic whole-body circulating", "legal_class": null }, { "id": 383, "slug": "gaba", "name": "GABA", "aliases": [ "Gamma-aminobutyric acid", "Gamma aminobutyric acid", "4-Aminobutanoic acid", "4-Aminobutyric acid" ], "type": "Non-peptide", "category": "Sleep / mood", "goals_use_cases": [ "sleep", "evening calm", "anxiety-adjacent talk", "caffeine jitters" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "gaba", "gamma aminobutyric acid", "gamma-aminobutyric acid", "4 aminobutanoic acid", "PharmaGABA", "gaba sleep", "gaba groggy", "quieter thoughts", "groggy next day", "caffeine jitters", "flushing", "sleep through the night", "no sleep improvement" ], "feel_search": [ "quieter thoughts", "groggy next day", "caffeine jitters", "flushing", "sleep through the night", "no sleep improvement" ], "summary": "GABA is an amino acid supplement people discuss for quieter thoughts and easier sleep.", "search_blob": "gaba gaba gamma-aminobutyric acid gamma aminobutyric acid 4-aminobutanoic acid 4-aminobutyric acid gaba gamma aminobutyric acid gamma-aminobutyric acid 4 aminobutanoic acid pharmagaba gaba sleep gaba groggy quieter thoughts groggy next day caffeine jitters flushing sleep through the night no sleep improvement sleep evening calm anxiety-adjacent talk caffeine jitters quieter thoughts groggy next day caffeine jitters flushing sleep through the night no sleep improvement gaba is an amino acid supplement people discuss for quieter thoughts and easier sleep. gaba is an amino acid supplement people discuss for quieter thoughts and easier sleep. reports include calmer thoughts, no effect and unwanted next-day grogginess. sleep / mood non-peptide systemic oral supplement discussed for calm and sleep, with variable whole-body effects. systemic whole-body circulating", "legal_class": null }, { "id": 384, "slug": "histidine", "name": "Histidine (L-histidine)", "aliases": [ "L-histidine", "L histidine", "Histidine" ], "type": "Non-peptide", "category": "Skin, hair & tissue remodeling", "goals_use_cases": [ "skin dryness / flaking discussion", "eczema / skin-barrier discussion" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "histadine", "l-histadine", "histidine eczema", "dry flaky skin", "skin barrier", "filaggrin", "dry skin", "flaky skin", "itch", "redness", "stubborn patches" ], "feel_search": [ "dry skin", "flaky skin", "itch", "redness", "stubborn patches" ], "summary": "Some oral users report less dryness and itch; others notice no change or more irritation.", "search_blob": "histidine (l-histidine) histidine l-histidine l histidine histidine histadine l-histadine histidine eczema dry flaky skin skin barrier filaggrin dry skin flaky skin itch redness stubborn patches skin dryness / flaking discussion eczema / skin-barrier discussion dry skin flaky skin itch redness stubborn patches some oral users report less dryness and itch; others notice no change or more irritation. some oral users report less dryness and itch; others notice no change or more irritation. skin, hair & tissue remodeling non-peptide systemic swallowed histidine is discussed for skin changes during repeated use. systemic whole-body circulating", "legal_class": null }, { "id": 385, "slug": "n-acetyl-d-glucosamine", "name": "N-acetyl-D-glucosamine", "aliases": [ "NAG", "GlcNAc", "N-acetylglucosamine", "N-acetyl glucosamine", "N-acetyl-D-glucosamine", "Acetylglucosamine" ], "type": "Non-peptide", "category": "Immune & inflammation adjacents", "goals_use_cases": [ "anxiety discussion", "gut comfort", "gut lining discussion", "joint supplement comparison" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "nag", "n acetyl d glucosamine", "n acetyl glucosamine", "n-acetylglucosamine", "glcnac", "acetylglucosamine", "NAG vs NAC", "NAG vs glucosamine sulfate", "inner tension", "edgy", "calm", "anxiety", "gut comfort", "brain fog", "sedated", "stomach upset" ], "feel_search": [ "inner tension", "edgy", "calm", "anxiety", "gut comfort", "brain fog", "sedated", "stomach upset" ], "summary": "People discuss quieter anxiety and gut comfort, with nonresponse, sedation and stomach upset also reported.", "search_blob": "n-acetyl-d-glucosamine n-acetyl-d-glucosamine nag glcnac n-acetylglucosamine n-acetyl glucosamine n-acetyl-d-glucosamine acetylglucosamine nag n acetyl d glucosamine n acetyl glucosamine n-acetylglucosamine glcnac acetylglucosamine nag vs nac nag vs glucosamine sulfate inner tension edgy calm anxiety gut comfort brain fog sedated stomach upset anxiety discussion gut comfort gut lining discussion joint supplement comparison inner tension edgy calm anxiety gut comfort brain fog sedated stomach upset people discuss quieter anxiety and gut comfort, with nonresponse, sedation and stomach upset also reported. people discuss quieter anxiety and gut comfort, with nonresponse, sedation and stomach upset also reported. immune & inflammation adjacents non-peptide systemic oral nag is discussed for anxiety and gut comfort; a joint blend is a different product. systemic whole-body circulating", "legal_class": null }, { "id": 386, "slug": "chondroitin-sulfate", "name": "Chondroitin sulfate", "aliases": [ "Chondroitin", "Chondroitin sulphate", "Condrosulf" ], "type": "Non-peptide", "category": "Healing & repair", "goals_use_cases": [ "joint comfort", "joint stiffness", "osteoarthritis discussion", "oral joint supplements" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "chondroitin", "chondroitin sulphate", "chondroiten", "chondroitine", "condroitin", "condrosulf", "joint pain", "joint stiffness", "glucosamine chondroitin MSM", "easier movement", "aching joints", "hip sting", "loose stools", "bloating", "constipation", "no improvement" ], "feel_search": [ "easier movement", "aching joints", "joint pain", "hip sting", "loose stools", "bloating", "constipation", "no improvement" ], "summary": "People describe less joint aching, no improvement, or digestive trouble with joint blends.", "search_blob": "chondroitin sulfate chondroitin-sulfate chondroitin chondroitin sulphate condrosulf chondroitin chondroitin sulphate chondroiten chondroitine condroitin condrosulf joint pain joint stiffness glucosamine chondroitin msm easier movement aching joints hip sting loose stools bloating constipation no improvement joint comfort joint stiffness osteoarthritis discussion oral joint supplements easier movement aching joints joint pain hip sting loose stools bloating constipation no improvement people describe less joint aching, no improvement, or digestive trouble with joint blends. people describe less joint aching, no improvement, or digestive trouble with joint blends. named chondroitin products and glucosamine/msm combinations need separate interpretation. healing & repair non-peptide systemic swallowed joint products; feeling better at one joint does not establish local delivery. systemic whole-body circulating", "legal_class": null }, { "id": 387, "slug": "msm", "name": "MSM (methylsulfonylmethane)", "aliases": [ "MSM", "Methylsulfonylmethane", "Methyl sulfonyl methane", "Dimethyl sulfone" ], "type": "Non-peptide", "category": "Healing & repair", "goals_use_cases": [ "joint comfort", "skin/hair", "recovery", "mood discussion" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "MSM", "methylsulfonylmethane", "dimethyl sulfone", "joint pain", "skin glow", "insomnia", "brain fog", "low mood", "joint comfort" ], "feel_search": [ "joint comfort", "skin glow", "insomnia", "brain fog", "low mood" ], "summary": "Joint and skin reports range from relief to no change, with insomnia and low mood in some accounts.", "search_blob": "msm (methylsulfonylmethane) msm msm methylsulfonylmethane methyl sulfonyl methane dimethyl sulfone msm methylsulfonylmethane dimethyl sulfone joint pain skin glow insomnia brain fog low mood joint comfort joint comfort skin/hair recovery mood discussion joint comfort skin glow insomnia brain fog low mood joint and skin reports range from relief to no change, with insomnia and low mood in some accounts. joint and skin reports range from relief to no change, with insomnia and low mood in some accounts. healing & repair non-peptide systemic people discuss oral msm for joint comfort, skin and whole-body effects. systemic whole-body circulating", "legal_class": null }, { "id": 388, "slug": "arginine", "name": "Arginine", "aliases": [ "L-arginine", "L arginine" ], "type": "Non-peptide", "category": "Performance / endurance", "goals_use_cases": [ "performance", "workout pumps", "blood-flow discussion", "erection quality" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "arginin", "l argenine", "L-arginine HCl", "arginine hydrochloride", "AAKG", "arginine alpha-ketoglutarate", "pump", "visible veins", "blood flow", "energy lift", "cold sores", "stomach upset" ], "feel_search": [ "pump", "visible veins", "blood flow", "energy lift", "cold sores", "stomach upset" ], "summary": "Arginine, usually called L-arginine on supplements, is discussed for workout pumps, visible veins and erection quality.", "search_blob": "arginine arginine l-arginine l arginine arginin l argenine l-arginine hcl arginine hydrochloride aakg arginine alpha-ketoglutarate pump visible veins blood flow energy lift cold sores stomach upset performance workout pumps blood-flow discussion erection quality pump visible veins blood flow energy lift cold sores stomach upset arginine, usually called l-arginine on supplements, is discussed for workout pumps, visible veins and erection quality. arginine, usually called l-arginine on supplements, is discussed for workout pumps, visible veins and erection quality. reports include nonresponse, gut trouble and disputed mood effects. performance / endurance non-peptide systemic oral supplement reports concern whole-body effects. systemic whole-body circulating", "legal_class": null }, { "id": 389, "slug": "citrulline", "name": "Citrulline", "aliases": [ "L-citrulline", "L citrulline", "Citrulline malate (form comparison)", "L-citrulline DL-malate (form comparison)" ], "type": "Non-peptide", "category": "Performance staples (biohacking overlap)", "goals_use_cases": [ "workout pumps", "performance", "blood-flow discussion", "erection-quality discussion" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "citrulline", "l citrulline", "citruline", "citrulline malate", "LCit", "pump", "no pump", "blood flow", "fading", "stomach burning", "palpitations", "erection quality" ], "feel_search": [ "pump", "no pump", "fading", "stomach burning", "palpitations", "erection quality" ], "summary": "L-citrulline is an amino acid studied orally; malate preparations add a second component and need separate\u2026", "search_blob": "citrulline citrulline l-citrulline l citrulline citrulline malate (form comparison) l-citrulline dl-malate (form comparison) citrulline l citrulline citruline citrulline malate lcit pump no pump blood flow fading stomach burning palpitations erection quality workout pumps performance blood-flow discussion erection-quality discussion pump no pump fading stomach burning palpitations erection quality l-citrulline is an amino acid studied orally; malate preparations add a second component and need separate\u2026 performance staples (biohacking overlap) non-peptide systemic oral systemic blood-flow and workout discussion; supplier blends are separate. systemic whole-body circulating", "legal_class": null }, { "id": 390, "slug": "glutamine", "name": "Glutamine", "aliases": [ "L-glutamine", "L glutamine" ], "type": "Non-peptide", "category": "Gut health & recovery", "goals_use_cases": [ "gut health", "stool consistency", "digestive comfort", "exercise recovery" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "glutamine", "l glutamine", "l-glutamine", "glutamin", "gut health", "stool consistency", "bloating", "muscle soreness", "steadier stools", "digestive discomfort", "anxiety" ], "feel_search": [ "steadier stools", "bloating", "digestive discomfort", "muscle soreness", "anxiety" ], "summary": "Glutamine is an amino acid people discuss for steadier stools, less digestive discomfort and recovery after training.\u2026", "search_blob": "glutamine glutamine l-glutamine l glutamine glutamine l glutamine l-glutamine glutamin gut health stool consistency bloating muscle soreness steadier stools digestive discomfort anxiety gut health stool consistency digestive comfort exercise recovery steadier stools bloating digestive discomfort muscle soreness anxiety glutamine is an amino acid people discuss for steadier stools, less digestive discomfort and recovery after training.\u2026 glutamine is an amino acid people discuss for steadier stools, less digestive discomfort and recovery after training. the oral reports include striking improvement, no change and unwanted gut or mood effects; a better bowel pattern does not necessarily mean less bloating. oral glutamine accounts are distinct from l-theanine and multi-ingredient injectable blends. gut health & recovery non-peptide systemic oral amino acid with gut-focused and training-recovery discussion. systemic whole-body circulating", "legal_class": null }, { "id": 391, "slug": "lysine", "name": "Lysine", "aliases": [ "L-Lysine", "L-lysine hydrochloride", "L-lysine monohydrochloride", "Lysine HCl" ], "type": "Non-peptide", "category": "Immune & inflammation adjacents", "goals_use_cases": [ "cold sores (discussed)", "HSV recurrence (discussed)", "outbreak duration (discussed)" ], "delivery_methods": [ "oral", "topical" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "lysine", "l lysine", "l-lysine", "lysine hcl", "llysine", "cold sore", "cold sores", "fever blister", "first tingle", "herpes supplement", "fewer outbreaks", "stomach pain", "nausea", "diarrhea" ], "feel_search": [ "cold sores", "first tingle", "fewer outbreaks", "stomach pain", "nausea", "diarrhea" ], "summary": "People discuss fewer cold sores or quicker recovery; others report no benefit or stomach trouble.", "search_blob": "lysine lysine l-lysine l-lysine hydrochloride l-lysine monohydrochloride lysine hcl lysine l lysine l-lysine lysine hcl llysine cold sore cold sores fever blister first tingle herpes supplement fewer outbreaks stomach pain nausea diarrhea cold sores (discussed) hsv recurrence (discussed) outbreak duration (discussed) cold sores first tingle fewer outbreaks stomach pain nausea diarrhea people discuss fewer cold sores or quicker recovery; others report no benefit or stomach trouble. people discuss fewer cold sores or quicker recovery; others report no benefit or stomach trouble. immune & inflammation adjacents non-peptide systemic usually discussed as an oral supplement; lip balms are separate topical products. systemic whole-body circulating", "legal_class": null }, { "id": 392, "slug": "vitamin-b6", "name": "Vitamin B6", "aliases": [ "Vitamin B6", "B6", "Vitamin B-6", "pyridoxine", "pyridoxine hydrochloride", "pyridoxine HCl", "pyridoxal 5-phosphate", "pyridoxal-5\u2032-phosphate", "P5P", "P-5-P", "PLP" ], "type": "Non-peptide", "category": "Longevity & cellular energy", "goals_use_cases": [ "calm / anxiety discussion", "focus / mental sharpness", "sleep / mood", "pyridoxine versus P5P", "supplement-related nerve symptoms" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "Vitamin B6", "B6", "Vitamin B-6", "pyridoxine", "pyridoxine hydrochloride", "pyridoxine HCl", "pyridoxal 5-phosphate", "pyridoxal-5\u2032-phosphate", "P5P", "P-5-P", "PLP", "pyroxidine", "pyridoxin", "calm focus", "brain fog", "anhedonia", "tingling", "neuropathy" ], "feel_search": [], "summary": "One vitamin family, different forms. Pyridoxine hydrochloride (HCl) and pyridoxal 5\u2032-phosphate (P5P, P-5-P\u2026", "search_blob": "vitamin b6 vitamin-b6 vitamin b6 b6 vitamin b-6 pyridoxine pyridoxine hydrochloride pyridoxine hcl pyridoxal 5-phosphate pyridoxal-5\u2032-phosphate p5p p-5-p plp vitamin b6 b6 vitamin b-6 pyridoxine pyridoxine hydrochloride pyridoxine hcl pyridoxal 5-phosphate pyridoxal-5\u2032-phosphate p5p p-5-p plp pyroxidine pyridoxin calm focus brain fog anhedonia tingling neuropathy calm / anxiety discussion focus / mental sharpness sleep / mood pyridoxine versus p5p supplement-related nerve symptoms one vitamin family, different forms. pyridoxine hydrochloride (hcl) and pyridoxal 5\u2032-phosphate (p5p, p-5-p\u2026 longevity & cellular energy non-peptide systemic systemic \u2014 a vitamin discussed for calm, mood and sleep. systemic whole-body circulating", "legal_class": null }, { "id": 393, "slug": "dexpanthenol", "name": "Dexpanthenol", "aliases": [ "D-panthenol", "panthenol", "provitamin B5" ], "type": "Non-peptide", "category": "Skin, hair & tissue remodeling", "goals_use_cases": [ "skin barrier / dryness discussion", "topical tolerance", "retinoid-routine comfort" ], "delivery_methods": [ "topical" ], "discussion_popularity": "Emerging", "reach": "Local", "misspellings_search_terms": [ "dexpanthenol", "dex panthenol", "d-panthenol", "panthenol", "pro vitamin b5", "b5 skin barrier", "tight skin", "flaky skin", "barrier repair", "bepanthen", "bepanthen plus", "flaking", "burning", "skin barrier", "retinoid dryness" ], "feel_search": [ "tight skin", "flaking", "burning", "skin barrier", "retinoid dryness" ], "summary": "Dexpanthenol, also called D-panthenol, comes up in skincare discussions about tight, flaky or irritated skin. Some\u2026", "search_blob": "dexpanthenol dexpanthenol d-panthenol panthenol provitamin b5 dexpanthenol dex panthenol d-panthenol panthenol pro vitamin b5 b5 skin barrier tight skin flaky skin barrier repair bepanthen bepanthen plus flaking burning skin barrier retinoid dryness skin barrier / dryness discussion topical tolerance retinoid-routine comfort tight skin flaking burning skin barrier retinoid dryness dexpanthenol, also called d-panthenol, comes up in skincare discussions about tight, flaky or irritated skin. some\u2026 dexpanthenol, also called d-panthenol, comes up in skincare discussions about tight, flaky or irritated skin. some users credit panthenol-containing products with helping their skin feel comfortable again; others notice little visible change or report burning. most of the useful accounts concern topical products, often alongside several other ingredients. topical product reports do not establish injectable blend effects. skin, hair & tissue remodeling non-peptide local the supported discussion concerns products applied to the skin. local site pin topical", "legal_class": null }, { "id": 394, "slug": "yohimbine", "name": "Yohimbine", "aliases": [ "Yohimbine HCl", "Yohimbine hydrochloride" ], "type": "Non-peptide", "category": "Mitochondrial & metabolic compounds", "goals_use_cases": [ "fat loss (discussed)", "workout energy (reported)", "appetite (discussed)", "anxiety (watch-for)", "sleep disruption (watch-for)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "yohimbin", "yohimbine hcl", "yohimbine hydrochloride", "yohimbe comparison", "rauwolscine comparison", "alpha yohimbine comparison", "stubborn fat", "fasted cardio", "tired but wired", "Kimera LIPO-NEX ingredient", "workout drive", "focus", "anxiety", "shakes", "sweats", "nausea", "insomnia", "racing heart" ], "feel_search": [ "workout drive", "focus", "anxiety", "shakes", "sweats", "nausea", "insomnia", "racing heart" ], "summary": "Yohimbine is a non-peptide compound people discuss for stubborn fat, fasted cardio and a stronger workout drive. Some\u2026", "search_blob": "yohimbine yohimbine yohimbine hcl yohimbine hydrochloride yohimbin yohimbine hcl yohimbine hydrochloride yohimbe comparison rauwolscine comparison alpha yohimbine comparison stubborn fat fasted cardio tired but wired kimera lipo-nex ingredient workout drive focus anxiety shakes sweats nausea insomnia racing heart fat loss (discussed) workout energy (reported) appetite (discussed) anxiety (watch-for) sleep disruption (watch-for) workout drive focus anxiety shakes sweats nausea insomnia racing heart yohimbine is a non-peptide compound people discuss for stubborn fat, fasted cardio and a stronger workout drive. some\u2026 yohimbine is a non-peptide compound people discuss for stubborn fat, fasted cardio and a stronger workout drive. some describe focus and energy; others get anxiety, nausea, shaking or lost sleep. much of the discussion concerns oral yohimbine hcl, and feeling stimulated does not show how much fat was lost. hcl, bark extracts, rauwolscine and multi-ingredient solutions require separate interpretation. mitochondrial & metabolic compounds non-peptide systemic people describe whole-body stimulation, including effects on training, mood and sleep. systemic whole-body circulating", "legal_class": null }, { "id": 395, "slug": "n-acetyl-l-tyrosine", "name": "N-acetyl-L-tyrosine (NALT)", "aliases": [ "NALT", "N acetyl L tyrosine", "N-acetyltyrosine", "acetyl L-tyrosine" ], "type": "Non-peptide", "category": "Cognitive research compounds", "goals_use_cases": [ "focus", "motivation", "mental energy", "stress-response discussion" ], "delivery_methods": [ "oral", "sublingual (unmeasured report)" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "nalt", "n acetyl tyrosine", "n acetyl l tyrosine", "acetyl tyrosine", "N-acetyl-L-tyrosine", "N-acetyltyrosine", "brain fog", "focus", "motivation", "mental energy", "agitation", "sleepiness" ], "feel_search": [ "brain fog", "focus", "motivation", "mental energy", "agitation", "sleepiness" ], "summary": "People discuss N-acetyl-L-tyrosine, or NALT, for focus, motivation and feeling more able to handle demanding days.\u2026", "search_blob": "n-acetyl-l-tyrosine (nalt) n-acetyl-l-tyrosine nalt n acetyl l tyrosine n-acetyltyrosine acetyl l-tyrosine nalt n acetyl tyrosine n acetyl l tyrosine acetyl tyrosine n-acetyl-l-tyrosine n-acetyltyrosine brain fog focus motivation mental energy agitation sleepiness focus motivation mental energy stress-response discussion brain fog focus motivation mental energy agitation sleepiness people discuss n-acetyl-l-tyrosine, or nalt, for focus, motivation and feeling more able to handle demanding days.\u2026 people discuss n-acetyl-l-tyrosine, or nalt, for focus, motivation and feeling more able to handle demanding days. some prefer it to plain l-tyrosine; others report no useful change, agitation or sleepiness. these are individual experiences, not established benefits. cognitive research compounds non-peptide systemic people discuss oral nalt for mental drive and focus. systemic whole-body circulating", "legal_class": null }, { "id": 396, "slug": "norvaline", "name": "Norvaline", "aliases": [ "L-norvaline", "L-2-aminopentanoic acid", "L-2-aminovaleric acid" ], "type": "Non-peptide", "category": "Performance / endurance", "goals_use_cases": [ "workout pump", "blood-flow discussion", "cognition debate" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "norvaline", "l norvaline", "l-norvaline", "norvalin", "pump", "neurotoxicity", "brain cells", "arginase", "muscle fullness", "headache", "no benefit" ], "feel_search": [ "pump", "muscle fullness", "headache", "no benefit" ], "summary": "Usually L-norvaline in supplement discussions. This is a non-protein amino acid: it is not one of the\u2026", "search_blob": "norvaline norvaline l-norvaline l-2-aminopentanoic acid l-2-aminovaleric acid norvaline l norvaline l-norvaline norvalin pump neurotoxicity brain cells arginase muscle fullness headache no benefit workout pump blood-flow discussion cognition debate pump muscle fullness headache no benefit usually l-norvaline in supplement discussions. this is a non-protein amino acid: it is not one of the\u2026 performance / endurance non-peptide systemic discussed as an oral ingredient acting throughout the body. systemic whole-body circulating", "legal_class": null }, { "id": 397, "slug": "acetyl-l-carnitine", "name": "Acetyl-L-carnitine (ALCAR)", "aliases": [ "ALCAR", "acetyl-L-carnitine", "L-acetylcarnitine", "acetylcarnitine" ], "type": "Non-peptide", "category": "Mitochondrial & metabolic compounds", "goals_use_cases": [ "focus", "brain fog", "mental fatigue", "energy", "mood" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "alcar", "acetyl l carnitine", "acetyl-l-carnitine", "acetyl carnitine", "l acetylcarnitine", "brain fog", "wired but tired", "mental fatigue", "insomnia", "focus", "energy", "irritability", "emotional numbness" ], "feel_search": [ "brain fog", "focus", "mental fatigue", "energy", "insomnia", "irritability", "emotional numbness" ], "summary": "Acetyl-L-carnitine (ALCAR) is discussed as an oral supplement for clearer thinking, less mental fatigue and more\u2026", "search_blob": "acetyl-l-carnitine (alcar) acetyl-l-carnitine alcar acetyl-l-carnitine l-acetylcarnitine acetylcarnitine alcar acetyl l carnitine acetyl-l-carnitine acetyl carnitine l acetylcarnitine brain fog wired but tired mental fatigue insomnia focus energy irritability emotional numbness focus brain fog mental fatigue energy mood brain fog focus mental fatigue energy insomnia irritability emotional numbness acetyl-l-carnitine (alcar) is discussed as an oral supplement for clearer thinking, less mental fatigue and more\u2026 acetyl-l-carnitine (alcar) is discussed as an oral supplement for clearer thinking, less mental fatigue and more drive. some users describe a useful lift; others feel nothing or become anxious, emotionally flat or unable to sleep. a noticeable boost does not establish improved brain health or treatment of a mood disorder. mitochondrial & metabolic compounds non-peptide systemic oral alcar is discussed for whole-body energy and mental effects. systemic whole-body circulating", "legal_class": null }, { "id": 398, "slug": "l-carnosine", "name": "L-carnosine", "aliases": [ "Carnosine", "Beta-alanyl-L-histidine", "\u03b2-alanyl-L-histidine" ], "type": "Peptide", "category": "Antioxidant & metabolic adjacents", "goals_use_cases": [ "cognition discussion", "verbal fluency", "energy", "exercise stamina", "glycation / healthy-aging discussion" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "l carnosine", "l-carnosine", "carnosin", "carnosine", "beta alanyl histidine", "verbal fluency", "glycation", "AGEs", "afternoon slump", "word finding", "stamina", "tingling", "wakefulness", "no benefit" ], "feel_search": [ "word finding", "verbal fluency", "afternoon slump", "stamina", "tingling", "wakefulness", "no benefit" ], "summary": "**Two amino acids joined together.** Carnosine, also called L-carnosine or beta-alanyl-L-histidine, consists\u2026", "search_blob": "l-carnosine l-carnosine carnosine beta-alanyl-l-histidine \u03b2-alanyl-l-histidine l carnosine l-carnosine carnosin carnosine beta alanyl histidine verbal fluency glycation ages afternoon slump word finding stamina tingling wakefulness no benefit cognition discussion verbal fluency energy exercise stamina glycation / healthy-aging discussion word finding verbal fluency afternoon slump stamina tingling wakefulness no benefit **two amino acids joined together.** carnosine, also called l-carnosine or beta-alanyl-l-histidine, consists\u2026 antioxidant & metabolic adjacents peptide systemic people discuss oral l-carnosine for thinking, energy and training. systemic whole-body circulating", "legal_class": null }, { "id": 399, "slug": "nadh", "name": "NADH", "aliases": [ "Reduced nicotinamide adenine dinucleotide", "Nicotinamide adenine dinucleotide (reduced)", "DPNH", "ENADA NADH" ], "type": "Non-peptide", "category": "Longevity & cellular energy", "goals_use_cases": [ "energy / fatigue (reported)", "brain fog / alertness (reported)", "mitochondrial discussion" ], "delivery_methods": [ "oral", "sublingual tablets / lozenges" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "nadh", "nad h", "reduced nad", "enada nadh", "dpnh", "nicotinamide adenine dinucleotide reduced", "fatigue", "brain fog", "mental clarity", "wired", "insomnia", "headache", "no effect" ], "feel_search": [ "fatigue", "brain fog", "mental clarity", "wired", "insomnia", "headache", "no effect" ], "summary": "People report clearer thinking or less fatigue, but also no change, worse fatigue and feeling too wired.", "search_blob": "nadh nadh reduced nicotinamide adenine dinucleotide nicotinamide adenine dinucleotide (reduced) dpnh enada nadh nadh nad h reduced nad enada nadh dpnh nicotinamide adenine dinucleotide reduced fatigue brain fog mental clarity wired insomnia headache no effect energy / fatigue (reported) brain fog / alertness (reported) mitochondrial discussion fatigue brain fog mental clarity wired insomnia headache no effect people report clearer thinking or less fatigue, but also no change, worse fatigue and feeling too wired. people report clearer thinking or less fatigue, but also no change, worse fatigue and feeling too wired. longevity & cellular energy non-peptide systemic people discuss whole-body fatigue and mental clarity, mainly with oral or sublingual products. systemic whole-body circulating", "legal_class": null }, { "id": 400, "slug": "saffron", "name": "Saffron", "aliases": [ "Crocus sativus", "Saffron extract", "Affron", "Safr\u2019Inside", "SafrInside" ], "type": "Non-peptide", "category": "Sleep / mood", "goals_use_cases": [ "mood", "sleep", "stress", "emotional steadiness" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "safron", "saffran", "crocus", "crocus sativus", "affron", "safrinside", "safr inside", "kesar", "low mood", "brain fog", "calmer", "irritability", "emotional steadiness", "sleepy", "sluggish", "anxiety", "no effect" ], "feel_search": [ "low mood", "brain fog", "calmer", "irritability", "emotional steadiness", "sleepy", "sluggish", "anxiety", "no effect" ], "summary": "Saffron is a spice and oral extract people discuss for mood, emotional steadiness and sleep.", "search_blob": "saffron saffron crocus sativus saffron extract affron safr\u2019inside safrinside safron saffran crocus crocus sativus affron safrinside safr inside kesar low mood brain fog calmer irritability emotional steadiness sleepy sluggish anxiety no effect mood sleep stress emotional steadiness low mood brain fog calmer irritability emotional steadiness sleepy sluggish anxiety no effect saffron is a spice and oral extract people discuss for mood, emotional steadiness and sleep. saffron is a spice and oral extract people discuss for mood, emotional steadiness and sleep. reports include benefit, no effect, sleepiness and increased anxiety; extract identity matters. sleep / mood non-peptide systemic oral spice and extracts discussed for mood and sleep. systemic whole-body circulating", "legal_class": null } ], "filters": { "categories": [ "Antioxidant & detox discussion", "Antioxidant & metabolic adjacents", "Antioxidant & performance adjacents", "Cognitive / nootropic peptides", "Cognitive research compounds", "Diuretics & fluid balance", "Experimental oncology-adjacent peptides", "Growth factors", "Growth factors / muscle", "Growth hormone axis", "Gut & inflammation peptides", "Gut health & recovery", "Healing & repair", "Healing stacks (named blends)", "Herbals in hormone discourse", "Hormone modulators", "Hormones in performance discourse", "Immune & inflammation adjacents", "Immune & neuropeptides", "Immune / antimicrobial", "Immune peptides", "Libido & melanocortin", "Longevity & bioregulators", "Longevity & cellular energy", "Longevity & mTOR", "Longevity & performance staples", "Metabolic & longevity adjacents", "Metabolic / GLP-1 class", "Metabolic / fat-loss peptides", "Metabolic / melanocortin", "Metabolic hormones", "Metabolic research compounds", "Minerals in hormone discourse", "Mitochondrial & metabolic compounds", "Mitochondrial & metabolic peptides", "Neuropeptides", "Organ bioregulators", "Performance / endurance", "Performance staples (biohacking overlap)", "Reproductive & endocrine peptides", "SARMs (adjacent discourse)", "Senolytic & longevity compounds", "Senolytic research peptides", "Sexual / reproductive", "Skin, hair & tissue remodeling", "Sleep & longevity staples", "Sleep / mood", "Stimulants / performance", "Stimulants in focus discourse", "Tanning & melanocortin", "Wakefulness agents in productivity discourse" ], "goals_use_cases": [ "AMPA modulation", "AMPK", "AMPK / nutrient-sensing interest", "AMPK pathway research tool", "Armour vs Synthroid (discussed)", "BDNF / TrkB narratives", "BPH", "BPH / urinary symptoms", "BPH-adjacent community stacks", "C60-in-olive-oil biohack", "CKD anemia (medical context)", "COURAGE triplet", "CR-mimetic framing", "DHT sides (watch-for)", "DIY multi-peptide serum building", "DIY serum booster culture", "DIY topical hair-serum culture", "DSIP comparison", "Dihexa stack (BioMind-class)", "EQ-adjacent (discussed)", "GH pulse amplitude (acute)", "GI lining support (discussed)", "GLP muscle-spare talk", "GLP-1 combination interest (CagriSema)", "GLP-1 compounding add-on", "GLP-1 pipeline talk", "GLP-1 stack adjunct (community)", "GLP-1 stack talk", "GLP-adjacent lean-mass talk", "HIV lipodystrophy context", "HPG axis research", "HPTA support (discussed)", "HSV recurrence (discussed)", "Huberman-class bone-peptide search", "Huberman-style nightly sleep cocktail", "IGF-1 elevation (discussed)", "IGF-1 elevation support (discussed)", "IGF-1 support (discussed)", "IV med-spa wellness menus", "K-beauty \u201csalmon DNA\u201d facial", "Long COVID discussion", "MC4R pathway research", "ME/CFS discussion", "ME/CFS metabolic discussion", "NAD discussion", "NAFLD / liver-fat curiosity", "NGF / nerve-growth talk", "NMN / NR partner", "NMN/NR stack companion", "NNMT discussion", "NSAID-related gut complaint talk", "NSAID-related gut irritation talk", "PCOS / cycle-regularity talk", "PCOS / insulin-resistance narratives", "PCOS-adjacent community", "PCT (discussed)", "PCT / post-cycle talk", "PCT SERM (discussed)", "PCT discussion", "PDE5 analogue comparison", "PPAR-gamma and metabolic discussion", "PWS anxiousness (investigational)", "PWS hyperphagia (investigational)", "Parkinson pipeline talk", "Parkinson\u2019s-related discussion", "RU-58841 comparison", "SERM (not an AI)", "SHBG (discussed)", "SHBG modulation (discussed)", "SIBO / bloating reports", "T-cell balance (discussed)", "T4+T3 mix (discussed)", "TBI recovery discussion", "TREK-1 (KCNK2) mechanism curiosity", "TRT", "TRT / high-E2 folklore", "TRT adjunct (discussed)", "TRT adjunct axis talk", "TRT alternative (discussed)", "TRT fertility preservation", "TRT-adjacent DHT discussion (contested)", "TRT-adjacent sexual function", "TSH (watch-for)", "Tren cardio offset (discussed)", "Wnt pathway discussion", "access / specialty-drug logistics", "acid-buffering discussion", "acne (labeled 1% cream)", "activin A blockade", "aesthetic remodeling", "aesthetic skin tone", "age-related GH decline discussion", "age-related cognitive interest", "age-related hepatic decline (discussed)", "age-related low-T talk (community)", "age-related metabolic decline", "aging", "aging cardiovascular support narratives", "aging male wellness (discussed)", "aging-brain repair narrative", "aging-brain support narratives", "alertness", "androgen-receptor block (discussed)", "androgenetic alopecia", "androgenetic alopecia (discussed)", "androgenetic alopecia add-on", "androgenetic alopecia pipeline", "angiogenesis support narratives", "anhedonia discussion", "anti fibrotic", "anti-aging (discussed)", "anti-aging / collagen talk", "anti-aging / wellness-clinic discussion", "anti-aging discussion", "anti-apoptotic cell-stress resilience", "anti-biofilm (preclinical)", "anti-catabolism (discussed)", "anti-fibrotic interest (discussed)", "anti-inflammaging narratives", "anti-inflammatory NAD-metabolome framing", "antimicrobial discussion", "antioxidant / DNA-damage narratives", "antioxidant / redox-cycling discussion", "antioxidant discussion", "antioxidant support (discussed)", "anxiety", "anxiety (discussed)", "anxiety (watch-for)", "anxiety / calm (discussed)", "anxiety discussion", "anxiety-adjacent talk", "apathy", "apathy / motivation discussion", "apigenin stack", "appetite", "appetite (discussed)", "appetite / hard-gainer bulk", "appetite and amylin signaling", "appetite control", "appetite control (GLP-1 arm)", "appetite control / food-noise reduction", "appetite regulation via MC4R", "appetite stimulation", "appetite suppression", "appetite suppression (discussed)", "approved peptide medicine", "arterial stiffness discussion", "attention", "autoimmune discussion", "autophagy / CR-mimetic framing", "autophagy discussion", "beard fill-in (topical community)", "between-Botox maintenance talk", "biased-agonist folklore", "bile flow / digestion", "bladder symptoms (clinical context)", "blood flow", "blood pressure experiments", "blood-flow discussion", "blood-pressure / potassium caution", "blood-pressure discussion", "blood-pressure support (discussed)", "body composition", "body composition (discussed)", "body composition / recomp", "body recomposition", "body recomposition (discussed)", "bodybuilding diuretic cautions", "bone / calcium-balance talk", "bone density", "bone density / osteoporosis", "bone discussion", "bone health", "bone metabolism interest (preclinical)", "bone support (discussed)", "bone support (preclinical interest)", "bone-building and follow-on treatment", "bowel effects", "brain fog", "brain fog (anecdotal)", "brain fog (discussed)", "brain mito quality", "breathing-comfort narratives", "bronchiectasis mucus-clearance talk", "brown fat", "bulking (community framing)", "caffeine jitters", "caffeine stack", "cagrilintide / CagriSema comparison", "cagrilintide / eloralintide comparison", "calm", "calm (discussed)", "calm / anxiety discussion", "calm focus", "cancer self-experimentation (discussed)", "cancer-risk observational interest", "cardiac/organ repair narratives", "cardio capacity (discussed)", "cardiometabolic risk discussion", "cardiometabolic risk markers (discussed)", "cardiometabolic risk talk", "cardiovascular", "cardiovascular / heart-tissue talk", "cardiovascular aging interest", "cardiovascular discussion", "catabolism (watch-for)", "celiac adjacency discussion", "cell-stress mechanisms (research)", "cellular NAD+ support", "cellular energy narratives", "cellular senescence research", "chromatin / gene-expression narratives", "chronic bronchitis adjunct talk", "chronic fatigue discussion", "chronic infection discussion", "chronic infection support narratives", "chronic insomnia research history", "circadian / melatonin talk", "circadian / pineal interest", "circadian rhythm discussion", "clinical-development updates", "cognition", "cognition (discussed)", "cognition / memory & attention", "cognition / memory talk", "cognition debate", "cognition discussion", "cognition under stress", "cognitive clarity (anecdotal)", "cold sores (discussed)", "collagen / firmness talk", "collagen discussion", "combinations with NAC", "combinations with minoxidil", "combinations with tirzepatide (research)", "comparison to FLGR-242", "comparisons after finasteride", "comparisons with finasteride", "comparisons with retatrutide", "competition drive (discussed)", "connective-tissue training support", "contest T4+T3 (discussed)", "contest prep (discussed)", "convenience / fewer injections", "cosmetic copper-peptide interest", "cosmetic matrix remodeling", "cosmetic peptide routines", "cramps (watch-for)", "craving reduction (discussed)", "cut (discussed)", "cut-phase conditioning", "cutting (discussed)", "cutting / anti-catabolism (discussed)", "cutting phase adjunct (community)", "cycling", "cytoprotection research (SHLP2/3)", "dandruff / seborrheic dermatitis", "dementia research interest", "depression research discussion", "depression-pipeline talk", "depression-with-insomnia trial talk", "detox discussion", "detoxification capacity narratives", "diabetes-adjacent research interest", "diagnostics adjacency", "diet-switch synergy (animal framing)", "digestion after gallbladder removal", "digestive comfort", "digestive enzyme aging discussion", "dopamine-related claims (unverified)", "dry appearance (discussed)", "dry look (discussed)", "dry oral (discussed)", "dryer oral size (discussed)", "dutasteride comparison", "early waking (reported downside)", "eczema / skin-barrier discussion", "emotional responsiveness", "emotional steadiness", "endometriosis pipeline (adjacent)", "endurance", "endurance (discussed)", "endurance (reported)", "endurance discussion", "energy", "energy & recovery (community)", "energy (discussed)", "energy (reported)", "energy / burnout narratives", "energy / fatigue (reported)", "energy / fatigue (subjective)", "energy / fatigue discussion", "energy / fatigue talk", "energy / vitality (discussed)", "energy discussion", "energy expenditure (discussed)", "energy-drink ingredient literacy", "erectile function discussion", "erection quality", "erection-quality discussion", "erections", "estradiol control", "estradiol crash (watch-for)", "estrogen from 19-nor (discussed)", "estrogen metabolism talk", "estrogen-control discussion", "evening calm", "exercise mimetic narratives", "exercise recovery", "exercise stamina", "exercise tolerance (discussed)", "exercise-mimetic research", "exercise-mimetic research framing", "exercise-mimetic research talk", "exercise\u2013mito peptide discussion", "expensive mild AAS (discussed)", "experimental oncology discussion", "eye health discussion", "fat loss", "fat loss (discussed)", "fat loss / obesity", "fat loss adjacency", "fat loss discussion", "fatigue", "fatigue (discussed)", "fatty-acid oxidation (discussed)", "fatty-acid oxidation shift (discussed)", "fatty-liver / metabolic discussion", "fertility", "fertility discussion", "fertility/TTC adjacency", "fibromyalgia discussion", "finasteride-avoid topical add-on", "fine lines & wrinkles", "fine-line smoothing narratives", "flexibility", "focus", "focus (discussed)", "focus / attention", "focus / memory combinations", "focus / mental sharpness", "focus / word-finding (discussed)", "focus / working memory", "follistatin-class comparison", "follow-on treatment discussions", "food noise reduction", "food noise reduction (discussed)", "food versus supplement sources", "food-first polyamine intake optimization", "food-noise reduction (dual pathway)", "forehead & crow's feet appearance", "fracture-risk discussions", "frailty compression narratives (mouse)", "free testosterone (discussed)", "free testosterone talk (community)", "geroprotection (research framing)", "glabellar / frown-line appearance", "glucose", "glucose / HbA1c adjacency", "glucose / HbA1c control", "glucose / glycemic discussion", "glutathione / antioxidant support", "glycation / healthy-aging discussion", "grain dosing (discussed)", "gray-market identity fights", "gut comfort", "gut health", "gut health (discussed)", "gut lining discussion", "gut-mood n=1 logs", "gym pumps", "gyno (discussed)", "gyno last-resort (discussed)", "gyno scare (discussed)", "hair / estrogen-dominance stacks", "hair density narratives", "hair regrowth discussion", "hardening (discussed)", "healthspan biomarkers (discussed)", "healthy aging / healthspan", "healthy aging biomarker interest", "heart", "heart rate (watch-for)", "heart-risk discussion", "hematocrit (discussed)", "hematopoiesis support (discussed)", "hepcidin / iron regulation", "high-intensity effort", "hormonal acne", "hormone axis", "hormone support", "hormone-axis neighbor stacks", "host-defense peptide research", "hyperphagia control (pathway-specific)", "hypogonadism discussion", "hypogonadotropic hypogonadism induction", "hypothalamic amenorrhea research context", "hypothyroid replacement (discussed)", "immune", "immune / NK-cell adjacency", "immune aging discussion (minority)", "immune modulation", "immune modulation (discussed)", "immune modulation discussion", "infection recovery support (discussed)", "inflammation (discussed)", "inflammation / SASP-burden narratives", "inflammation / mast-cell lore", "inflammation balance (discussed)", "inflammation discussion", "inflammation markers (CRP/IL-6 talk)", "inflammation models (preclinical)", "inflammation moderation (discussed)", "inflammation modulation (double-edged)", "inflammation talk", "inflammation-metabolic research", "injection pain (watch-for)", "injury repair", "injury-adjacent downtime reduction talk", "injury-return training (discussed)", "injury-season recovery adjacency", "insulin sensitivity", "insulin sensitivity (discussed)", "insulin-sensitivity talk", "insurance / prior-auth discussion", "interstitial cystitis (labeled oral)", "jet lag", "joint comfort", "joint comfort (discussed)", "joint stiffness", "joint supplement comparison", "joints & tendons", "joints / osteoarthritis discussion", "joints discussion", "language learning", "leaky-gut / permeability narratives", "leaky-gut forum framing", "lean mass (discussed)", "lean mass (research context)", "lean mass preservation", "lean mass preservation (discussed)", "lean mass retention (discussed)", "lean recomp (discussed)", "lean-mass preservation", "learning (claimed)", "libido", "libido (discussed)", "libido (split)", "libido adjacency", "libido and intimacy", "lipid and blood-pressure markers", "lipid markers (preclinical discussion)", "lipid profile (discussed)", "lipids (watch-for)", "lipolysis support (discussed)", "liver (watch-for)", "liver / fatty-liver adjacency", "liver fat discussion", "liver support discussion", "liver-enzyme discussions", "liver-injury discussion", "local muscle volume", "local myostatin blockade", "localized growth discussion", "long-COVID stack", "longevity", "longevity (discussed)", "longevity (lifestyle adjacent)", "longevity / SGLT2 talk", "longevity / anti-aging narrative", "longevity / antioxidant talk", "longevity / bioregulator courses", "longevity / cellular energy", "longevity / chromatin-aging interest", "longevity / geroprotection narratives", "longevity / geroprotection talk", "longevity / geroprotector stacks", "longevity / geroscience baseline", "longevity / geroscience discussion", "longevity / healthspan", "longevity / healthspan (discussed)", "longevity / healthspan discussion", "longevity / healthy aging", "longevity / healthy-aging stacks", "longevity / multi-bioregulator calendars", "longevity / musculoskeletal aging", "longevity / organ-bioregulator calendars", "longevity claims (unverified)", "longevity clinic protocols", "longevity discussion", "longevity nootropic", "longevity research discussion", "longevity-adjacent IGF-pathway interest", "losartan comparison", "maculopathy watch-for", "male vitality (discussed)", "mast-cell / histamine folklore", "mast-cell / histamine talk", "memory", "memory & learning (discussed)", "memory (research discussion)", "memory / learning (discussed)", "memory / learning discussion", "memory / learning support (discussed)", "memory / recall", "memory / recall (discussed)", "memory discussion", "men's health discussion", "mental clarity", "mental clarity (anecdotal)", "mental clarity (discussed)", "mental energy", "mental fatigue", "mental health adjacency", "mental performance under stress", "metabolic / fuel-preference research", "metabolic / redox talk", "metabolic aging interest", "metabolic health", "metabolic health (discussed)", "metabolic health discussion", "metabolic markers (discussed)", "metabolic rate (discussed)", "metabolic research", "metabolic syndrome marker interest", "metformin comparison", "methylation", "methylation / MTHFR folklore", "methylation / homocysteine", "methylation discussion", "microdose lithium", "microneedling add-on", "mild dry-eye discussion", "min/fin stack staple", "minoxidil stack", "minoxidil-alternative mechanism", "mitochondria", "mitochondrial / energy narratives", "mitochondrial discussion", "mitochondrial function", "mitochondrial function / cytoprotection", "mitochondrial support (discussed)", "mitochondrial uncoupling research tool", "mitophagy / mitochondrial recycling", "mobility", "mobility & morning stiffness (community)", "mobility / flexibility", "mold illness discussion", "mood", "mood (discussed)", "mood (reported)", "mood (secondary discussion)", "mood / NMDA talk", "mood / affiliative affect", "mood / anhedonia talk", "mood / emotional baseline", "mood / motivation (anecdotal)", "mood / stress (discussed)", "mood / vitality (discussed)", "mood discussion", "mood steadiness", "morning grogginess (discussed)", "motivation", "motivation (discussed)", "motivation (reported)", "motivation / social-effect reports", "multiple sclerosis symptom discussion", "muscle", "muscle growth", "muscle growth / hypertrophy (discussed)", "muscle preservation", "muscle soft-tissue", "muscle strain recovery", "muscle-sparing cut talk", "mushroom coffee stacks", "myostatin discussion", "myostatin inhibition", "myostatin inhibition pathway interest", "nails", "nasal tanning spray interest", "needle-averse GLP-1 access interest", "needle-free peptide interest", "nerve pain experiments", "nerve regeneration research", "nerve repair lore (discussed)", "neurogenesis discussion", "neuroimmune regulation (discussed)", "neuropathy discussion", "neuropathy talk", "neuroplasticity discussion", "neuroprotection (discussed)", "neuroprotection (preclinical)", "neuroprotection discussion", "neuroprotection discussion (SHLP2)", "night sweats (watch-for)", "nocturia / overactive-bladder talk", "nocturia talk", "nocturnal GH pulse amplification", "non-GLP hunger talk", "non-injectable Botox-alternative talk", "non-producer food-bypass strategy", "nootropic stacks", "nutrient partitioning (discussed)", "nutrient partitioning discussion", "obesity combination trials", "obesity management research", "obesity research (pipeline comparisons)", "obesity research models", "obesity research tools", "omega-3 index", "oncology adjunct (discussed)", "oral GLP talk", "oral GLP-1 research", "oral dual-agonist curiosity", "oral joint supplements", "oral versus injected medicines", "oral vs injection HA", "orexin / DORA comparison", "orforglipron comparison", "osteoarthritis discussion", "osteoporosis", "outbreak duration (discussed)", "overactive-bladder talk", "pain discussion", "parathyroid-support narratives", "perceived endurance", "performance", "performance (resistance training)", "performance / exercise capacity", "performance / strength (discussed)", "performance / training continuity", "performance / training quality", "performance continuity", "performance continuity (cognitive)", "performance continuity (discussed)", "performance continuity while leaning", "phenibut tolerance (disputed)", "photoaging appearance", "photoprotection discussion", "pineal bioregulator interest", "pituitary GH stimulation (discussed)", "pituitary prolactinoma research context", "planned combo with petrelintide", "plaque / CIMT hype", "polycythemia vera talk", "post-AAS HPTA restart talk", "post-AAS recovery narratives", "post-course antiresorptive lock-in", "post-exposure recovery narratives", "post-illness convalescence (discussed)", "post-laser recovery talk", "post-overuse repair", "post-procedure aesthetic recovery", "post-procedure calm-down", "post-procedure recovery talk", "post-strain / overuse bounce-back", "post-strain bounce-back", "post-stress heart-support narratives", "post-stroke discussion", "post-surgical soft-tissue talk", "post-viral immune-support talk", "post-workout muscle repair talk", "pre-workout energy", "pre-workout ergogenic interest", "productivity (discussed)", "prolactin discussion", "prolactin-receptor hair (discussed)", "proposed bladder GAG-layer protection", "prostate support narratives", "prostate-adjacent urinary flow talk", "pulmonary fibrosis research interest", "pumps (discussed)", "pyridoxine versus P5P", "pyrilutamide / RU-58841 comparison", "pyrilutamide comparison", "quality mass (discussed)", "racetam-related headache discussion", "rancid oil watch-for", "rapid size (discussed)", "rapid strength (discussed)", "rare obesity pathway discussion", "recomp", "recomposition", "recomposition (discussed)", "recovery", "recovery (route-debated)", "recovery (secondary discussion)", "recovery / DOMS discussion", "recovery / DOMS talk", "recovery / burnout reset", "recovery / next-day readiness", "recovery / training continuity", "recovery / training continuity (discussed)", "recovery / training readiness", "recovery after exertion (reported)", "recovery after hard sessions", "recovery and exercise tolerance", "recovery continuity", "recovery continuity (discussed)", "recovery continuity alongside training", "red blood cells (watch-for)", "relaxation (discussed)", "renal fibrosis research interest", "repurposed-drug claims", "research IM peptide", "respiratory / lung-support talk", "respiratory / mucolytic discussion", "respiratory discussion", "reta comparison", "retinoid-routine comfort", "rumination", "running", "sarcoidosis-associated neuropathic pain", "sarcopenia-adjacent", "satiety / meal-size reduction", "scalp / follicle discussion", "scalp / hair appearance", "scalp mesotherapy", "scar / texture narratives", "scar/fibrosis talk", "seasonal resilience talk", "secondary hypogonadism discussion", "sedation (reported)", "senolytic discussion", "senolytic stack discussion", "sensory changes (reported)", "sensory vividness", "sensory vividness (discussed)", "sexual function", "sexual function (discussed)", "sexual health", "sexual performance", "shedding and hair maintenance", "shedding and itch reports", "short run (discussed)", "skin", "skin / recovery adjacency", "skin elasticity discussion", "skin/hair", "skin/hair (minority discussion)", "skin/hair / photoaging adjacency", "sleep", "sleep (GH-axis adjacency)", "sleep (discussed)", "sleep (mixed reports)", "sleep / Huberman-night add-on", "sleep / Huberman-night stack", "sleep / calm (minority)", "sleep / mood", "sleep adjacency", "sleep adjacency (discussed)", "sleep balance (discussed; mixed)", "sleep disruption (side)", "sleep disruption (watch-for)", "sleep onset", "sleep onset (discussed)", "sleep onset / latency", "sleep quality & REM narratives", "sleep quality (mixed reports)", "sleep quality (open-label discussion)", "sleep quality (secondary discussion)", "sleep quality / depth", "sleep quality discussion", "slow vs T3 (discussed)", "slower than Dbol (discussed)", "small fiber neuropathy (SFN)", "sociability", "social anxiety (discussed)", "social anxiety discussion", "social bonding discussion", "social ease (reported)", "social enjoyment", "soft-tissue", "soft-tissue healing", "soft-tissue healing (route comparison)", "spermatogenesis support", "spine T-score talk", "stimulant crash", "stimulant-tolerance lore", "stool consistency", "strength", "strength & power", "strength continuity (discussed)", "stress", "stress (discussed)", "stress / cortisol (discussed)", "stress load composure (anecdotal)", "stress-related cognitive symptoms", "stress-response discussion", "strong AI (discussed)", "study / deep-work performance", "study / learning (discussed)", "study / productivity (discussed)", "study / work concentration", "study retention", "suicidal AI (discussed)", "sunless / UV-assisted bronze", "supplement-related nerve symptoms", "suppression (discussed)", "sustained GH/IGF-1 elevation research", "synaptic plasticity (preclinical)", "synaptogenesis / spinogenesis narrative", "systemic repair narrative", "tanning / pigmentation", "telomerase (hTERT) activation talk", "telomere discussion", "testicular function / anti-atrophy", "testicular volume (with hCG)", "testosterone support (discussed)", "texture & density narratives", "texture & tone narratives", "thermogenesis", "thyroid mimic (discussed)", "thyroid replacement (discussed)", "thyroid suppression (watch-for)", "tight junction discussion", "tirzepatide-class dual comparison", "tissue remodeling discussion", "topical anti-androgen DIY", "topical tolerance", "topical-formulation differences", "total testosterone (discussed)", "training drive", "training recovery continuity", "tremor (watch-for)", "triamterene combination comparison", "triglycerides", "trunk / midsection aesthetics", "twice-weekly scalp routine talk", "ulcer-adjunct discussion", "urinary calcium conservation (discussed)", "urologic wellness interest (community)", "vaccine response interest", "vascular dementia discussion", "vascular discussion", "vascular encephalopathy support talk", "vascularity (discussed)", "verbal fluency", "verbal fluency (reported)", "verbal fluency (self-report theme)", "verbal fluency / word-finding", "verbal recall", "visceral fat (clinical signal)", "visceral fat discussion", "visceral fat reduction (discussed)", "vs ABS-201 (discussed)", "vs Follistatin 344", "vs HMI-115 (discussed)", "vs Nolvadex (discussed)", "vs magnesium glycinate", "vs metformin", "vs psychiatric lithium carbonate", "waist / midsection aesthetics", "waist / visceral-fat talk", "wakefulness", "wakefulness (discussed)", "water (watch-for)", "water retention discussion", "wearable sleep-score n=1s", "weight management / obesity", "weight management research", "weight management without injections", "wellness-clinic IV lounge culture", "working memory (discussed)", "workout capacity", "workout drive", "workout energy (reported)", "workout pump", "workout pumps", "wound narratives", "wound-adjacent follicle neogenesis talk", "wound/scar remodeling talk", "yearly bioregulator course calendars", "zinc ionophore narrative (community)", "\u201cGLP nausea-lite\u201d amylin story", "\u201cgiga urolithin\u201d talk" ], "delivery_methods": [ "IV", "gene therapy discussion", "implant", "implant (clinical)", "injected", "injection", "injection discussion", "intradermal", "intramuscular", "microneedling adjacency", "nasal", "nebulized (discussed)", "oral", "pre-mixed multi-peptide vial", "pulsatile pump (clinical discussion)", "rectal", "rectal (isolated report)", "research", "research injection discussion", "research injection in animal work", "research peptide injection discussion", "research routes", "research use discussion only", "separate vials or pre-mixed blend", "subcutaneous", "sublingual", "sublingual (marketed)", "sublingual (reported)", "sublingual (separate anecdotal context)", "sublingual (unmeasured report)", "sublingual tablets / lozenges", "topical", "transdermal (discussed)", "unspecified in inspected firsthand reports" ], "types": [ "Peptide", "Non-peptide" ], "reach": [ "Systemic", "Local", "Mixed" ], "popularity": [ "High", "Medium", "Emerging" ], "quick_goals": [ "fat loss", "muscle growth", "recovery", "sleep", "longevity", "cognition", "skin/hair", "libido", "gut health", "performance", "immune", "appetite control", "injury repair", "inflammation", "focus", "mood" ] } }