{ "generated": "2026-08-16", "count": 311, "voice": "biohacker-expanded", "ranking_note": "Discussion volume only \u2014 not medical importance or efficacy.", "compounds": [ { "id": 1, "slug": "bpc-157", "name": "BPC-157", "aliases": [ "Body Protection Compound-157", "BPC157", "PL 14736", "BPC 157", "PL14736", "PL-10 (oral Bepecin trial code discussions)", "Bepecin (research designation)", "Stable gastric pentadecapeptide BPC 157", "Pentadeca arginate / PDA (arginate salt marketing name)", "Arg-BPC / BPC-157 arginate (oral-stability form talk)" ], "type": "Peptide", "category": "Healing & repair", "goals_use_cases": [ "recovery", "injury repair", "gut health", "joints & tendons", "soft-tissue healing", "inflammation (discussed)", "muscle strain recovery", "post-overuse repair", "GI lining support (discussed)", "performance continuity", "post-surgical soft-tissue talk", "NSAID-related gut complaint talk" ], "delivery_methods": [ "subcutaneous", "oral" ], "discussion_popularity": "High", "reach": "Mixed", "misspellings_search_terms": [ "bpc-157", "bpc 157", "bpc157", "Body Protection Compound-157", "PL 14736", "PL14736", "tendon pain", "achilles", "tennis elbow", "gut", "healing", "injury", "recovery", "wolverine", "pcac", "503a", "compounding", "fda approved", "nasal bpc", "site injection", "belly vs site", "nasal", "anhedonia", "site pin" ], "feel_search": [ "tendon pain", "achilles", "tennis elbow", "gut", "healing", "injury", "recovery", "wolverine", "nasal", "anhedonia", "site pin" ], "summary": "BPC-157 is a synthetic 15-amino-acid peptide discussed for tendon and injury recovery, stiffness and gut symptoms. Users report multi-week drop in daily pain/irritation noise.", "search_blob": "bpc-157 bpc-157 body protection compound-157 bpc157 pl 14736 bpc 157 pl14736 pl-10 (oral bepecin trial code discussions) bepecin (research designation) stable gastric pentadecapeptide bpc 157 pentadeca arginate / pda (arginate salt marketing name) arg-bpc / bpc-157 arginate (oral-stability form talk) bpc-157 bpc 157 bpc157 body protection compound-157 pl 14736 pl14736 tendon pain achilles tennis elbow gut healing injury recovery wolverine pcac 503a compounding fda approved nasal bpc site injection belly vs site nasal anhedonia site pin recovery injury repair gut health joints & tendons soft-tissue healing inflammation (discussed) muscle strain recovery post-overuse repair gi lining support (discussed) performance continuity post-surgical soft-tissue talk nsaid-related gut complaint talk tendon pain achilles tennis elbow gut healing injury recovery wolverine nasal anhedonia site pin bpc-157 is a synthetic 15-amino-acid peptide discussed for tendon and injury recovery, stiffness and gut symptoms. users report multi-week drop in daily pain/irritation noise. reports mix less shoulder pain with nausea, palpitations, feeling detached or stomach discomfort. self-rated relief is not proof of tissue healing. bpc-157 is a synthetic 15-amino-acid peptide discussed for tendon and injury recovery, stiffness and gut symptoms. users report multi-week drop in daily pain/irritation noise. biggest stories are achilles, elbow, knee, and gut. july 2026 compounding-vote headlines are not \u201cfda approved.\u201d a lot of logs also run it next to tb-500 (wolverine), so credit gets messy. healing & repair peptide mixed mixed \u2014 near-injury pin for a limb, belly for whole-body/gut talk. people argue both. mixed local systemic", "legal_class": null }, { "id": 2, "slug": "semaglutide", "name": "Semaglutide", "aliases": [ "Ozempic", "Wegovy", "Rybelsus", "sema", "Sema", "Semaglutide acetate (research/compounded discussions)", "Semaglutide sodium (research/compounded salt form \u2014 FDA concern)", "NN9535 (developmental designation, historical)", "GLP-1 RA / weekly GLP-1" ], "type": "Peptide", "category": "Metabolic / GLP-1 class", "goals_use_cases": [ "fat loss", "appetite control", "metabolic health", "glucose", "food noise reduction", "glucose / glycemic discussion", "weight management / obesity", "type 2 diabetes (approved context)", "cardiometabolic risk talk", "body recomposition (confounded by lean loss)", "diabetes-adjacent research interest", "microdosing / low-dose aesthetic or maintenance talk" ], "delivery_methods": [ "subcutaneous", "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "semaglutide", "Ozempic", "Wegovy", "Rybelsus", "Sema", "Semaglutide acetate (research/compounded discussions)", "food noise", "appetite", "nausea", "full fast", "fat loss", "compounding", "research use only", "alcohol", "muscle loss", "ozempic", "wegovy", "ozempic face" ], "feel_search": [ "food noise", "appetite", "nausea", "ozempic", "wegovy", "full fast", "fat loss", "compounding", "research use only", "alcohol", "muscle loss", "ozempic face" ], "summary": "Semaglutide is a long-acting GLP-1 analogue used in diabetes and weight-related medicines; brands, indications and oral/injection forms differ.", "search_blob": "semaglutide semaglutide ozempic wegovy rybelsus sema sema semaglutide acetate (research/compounded discussions) semaglutide sodium (research/compounded salt form \u2014 fda concern) nn9535 (developmental designation, historical) glp-1 ra / weekly glp-1 semaglutide ozempic wegovy rybelsus sema semaglutide acetate (research/compounded discussions) food noise appetite nausea full fast fat loss compounding research use only alcohol muscle loss ozempic wegovy ozempic face fat loss appetite control metabolic health glucose food noise reduction glucose / glycemic discussion weight management / obesity type 2 diabetes (approved context) cardiometabolic risk talk body recomposition (confounded by lean loss) diabetes-adjacent research interest microdosing / low-dose aesthetic or maintenance talk food noise appetite nausea ozempic wegovy full fast fat loss compounding research use only alcohol muscle loss ozempic face semaglutide is a long-acting glp-1 analogue used in diabetes and weight-related medicines; brands, indications and oral/injection forms differ. users describe quieter appetite with occasional hungry days; one long-term user still craved more food before the next shot. semaglutide is a glp-1 medicine people discuss for quieter appetite and less food noise, not a stimulant-like fat-loss feeling. food interest may already drop. people copy a slow climb because the stomach sides hit when they jump. brand names people search: ozempic / wegovy. metabolic / glp-1 class peptide systemic whole-body \u2014 appetite and stomach-emptying, not a local fat pin. systemic whole-body circulating", "legal_class": null }, { "id": 3, "slug": "tirzepatide", "name": "Tirzepatide", "aliases": [ "Mounjaro", "Zepbound", "tirz", "TZP", "LY3298176", "dual GIP/GLP-1 agonist", "twincretin (informal)" ], "type": "Peptide", "category": "Metabolic / GLP-1 class", "goals_use_cases": [ "fat loss", "appetite control", "metabolic health", "glucose", "appetite control / food-noise reduction", "glucose / HbA1c (T2D labeled context)", "weight management / obesity", "type 2 diabetes (approved context)", "obstructive sleep apnea (Zepbound labeled discussion)", "body recomposition (discussed; muscle-preservation focus)", "cardiometabolic risk markers (discussed)", "waist / visceral-fat talk" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "tirzepatide", "Mounjaro", "Zepbound", "tirz", "TZP", "LY3298176", "food noise", "appetite", "nausea", "fat loss", "compounding", "research use only", "alcohol", "split dose", "B12", "mounjaro", "zepbound" ], "feel_search": [ "food noise", "appetite", "nausea", "mounjaro", "zepbound", "fat loss", "compounding", "research use only", "alcohol", "split dose", "B12" ], "summary": "Tirzepatide is an injectable peptide activating GIP and GLP-1 receptors, used in diabetes and weight-related medicines.", "search_blob": "tirzepatide tirzepatide mounjaro zepbound tirz tzp ly3298176 dual gip/glp-1 agonist twincretin (informal) tirzepatide mounjaro zepbound tirz tzp ly3298176 food noise appetite nausea fat loss compounding research use only alcohol split dose b12 mounjaro zepbound fat loss appetite control metabolic health glucose appetite control / food-noise reduction glucose / hba1c (t2d labeled context) weight management / obesity type 2 diabetes (approved context) obstructive sleep apnea (zepbound labeled discussion) body recomposition (discussed; muscle-preservation focus) cardiometabolic risk markers (discussed) waist / visceral-fat talk food noise appetite nausea mounjaro zepbound fat loss compounding research use only alcohol split dose b12 tirzepatide is an injectable peptide activating gip and glp-1 receptors, used in diabetes and weight-related medicines. some users describe quieter food thoughts and easier satiety; others still feel hungry despite finding overeating uncomfortable. tirzepatide is a weekly medicine people look up for appetite. strong early drop in hunger, portion size, snacking, and \u201cthinking about food\u201d. still a weekly shot climb. gi sides are the limiter. mounjaro / zepbound are the names people type. metabolic / glp-1 class peptide systemic systemic \u2014 dual gip/glp-1 receptor agonist; whole-body appetite, delayed gastric emptying, insulin/glucagon balance, and glucose effects. systemic whole-body circulating", "legal_class": null }, { "id": 4, "slug": "retatrutide", "name": "Retatrutide", "aliases": [ "LY3437943", "reta", "triple agonist", "Reta", "Triple agonist", "Triple-G agonist", "GLP-3 (informal community nickname)", "GIP/GLP-1/glucagon triple agonist", "Lilly triple agonist" ], "type": "Peptide", "category": "Metabolic / GLP-1 class", "goals_use_cases": [ "fat loss", "appetite control", "metabolic health", "appetite control / food-noise reduction", "body recomposition (discussed; large absolute loss includes some lean mass)", "glycemic control (T2D trial context)", "liver fat / MASLD reduction (trial substudy)", "cardiometabolic markers (BP, lipids, waist)", "obesity research (investigational, not FDA-approved as of last research)", "knee OA pain and OSA secondary outcomes (Phase 3 program talk)", "lean-user microdose recomp (community, unvalidated)" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "retatrutide", "LY3437943", "Reta", "Triple agonist", "Triple-G agonist", "GLP-3 (informal community nickname)", "food noise", "fat loss", "nausea", "compounding", "research use only", "ratatouille", "alcohol", "muscle loss", "reta", "triple agonist" ], "feel_search": [ "food noise", "reta", "triple agonist", "fat loss", "nausea", "compounding", "research use only", "ratatouille", "alcohol", "muscle loss" ], "summary": "Retatrutide (LY3437943) is an investigational injectable peptide that activates GIP, GLP-1 and glucagon receptors for weight-related treatment.", "search_blob": "retatrutide retatrutide ly3437943 reta triple agonist reta triple agonist triple-g agonist glp-3 (informal community nickname) gip/glp-1/glucagon triple agonist lilly triple agonist retatrutide ly3437943 reta triple agonist triple-g agonist glp-3 (informal community nickname) food noise fat loss nausea compounding research use only ratatouille alcohol muscle loss reta triple agonist fat loss appetite control metabolic health appetite control / food-noise reduction body recomposition (discussed; large absolute loss includes some lean mass) glycemic control (t2d trial context) liver fat / masld reduction (trial substudy) cardiometabolic markers (bp, lipids, waist) obesity research (investigational, not fda-approved as of last research) knee oa pain and osa secondary outcomes (phase 3 program talk) lean-user microdose recomp (community, unvalidated) food noise reta triple agonist fat loss nausea compounding research use only ratatouille alcohol muscle loss retatrutide (ly3437943) is an investigational injectable peptide that activates gip, glp-1 and glucagon receptors for weight-related treatment. one user described markedly quieter food thoughts but strong hunger as the next injection approached; replies reported different appetite patterns. retatrutide is a peptide for fat loss. first appetite drop, early fullness, mild nausea \u2014 or almost nothing until dose rises; injection-day fatigue sometimes noted. still weekly climb talk. numbers come from trial arms and copied vendor charts, not a shop label. metabolic / glp-1 class peptide systemic whole-body appetite, glucose and energy-expenditure effects; not a local tissue injection. systemic whole-body circulating", "legal_class": null }, { "id": 5, "slug": "tb-500", "name": "TB-500", "aliases": [ "Thymosin Beta-4 fragment", "TB500", "TB-500 acetate", "Ac-LKKTETQ (analytical ID of many TB-500 products)", "T\u03b24 fragment (community shorthand)", "LKKTETQ / T\u03b24 (17\u201323) actin-binding region", "TB-4 frag (often misused label)" ], "type": "Peptide", "category": "Healing & repair", "goals_use_cases": [ "recovery", "injury repair", "flexibility", "soft-tissue", "soft-tissue healing", "joints & tendons", "inflammation (discussed)", "mobility", "performance continuity", "muscle soft-tissue", "systemic repair narrative", "post-strain / overuse bounce-back", "scar-tissue / flexibility talk (often mixed with full T\u03b24 claims)" ], "delivery_methods": [ "subcutaneous", "intramuscular" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "tb-500", "tb 500", "tb500", "TB-500 acetate", "Thymosin Beta-4 fragment", "Ac-LKKTETQ (analytical ID of many TB-500 products)", "flexibility", "mobility", "strain", "recovery", "stiff", "wolverine", "pcac", "503a", "compounding", "fda approved", "nasal tb-500", "tb4 nasal" ], "feel_search": [ "flexibility", "mobility", "strain", "recovery", "stiff", "wolverine" ], "summary": "TB-500 is a research peptide sold as a thymosin beta-4 fragment for injury-recovery interests; the label is often confused with full-length T\u03b24.", "search_blob": "tb-500 tb-500 thymosin beta-4 fragment tb500 tb-500 acetate ac-lkktetq (analytical id of many tb-500 products) t\u03b24 fragment (community shorthand) lkktetq / t\u03b24 (17\u201323) actin-binding region tb-4 frag (often misused label) tb-500 tb 500 tb500 tb-500 acetate thymosin beta-4 fragment ac-lkktetq (analytical id of many tb-500 products) flexibility mobility strain recovery stiff wolverine pcac 503a compounding fda approved nasal tb-500 tb4 nasal recovery injury repair flexibility soft-tissue soft-tissue healing joints & tendons inflammation (discussed) mobility performance continuity muscle soft-tissue systemic repair narrative post-strain / overuse bounce-back scar-tissue / flexibility talk (often mixed with full t\u03b24 claims) flexibility mobility strain recovery stiff wolverine tb-500 is a research peptide sold as a thymosin beta-4 fragment for injury-recovery interests; the label is often confused with full-length t\u03b24. reports range from less stiffness to headache and fatigue; combination use, rehabilitation and supplements make attribution difficult. tb-500 is a peptide people look up for recovery. people report faster multi-week recovery from strains, tweaks, and training overuse. people talk flexibility and strains more than a single pinpoint injury. easy to mix up units with bpc. july 2026 compounding-vote headlines are not \u201cfda approved,\u201d and nasal tb is mostly called too big or the wrong molecule. healing & repair peptide systemic whole-body recovery talk \u2014 most logs treat the injection site as \u201canywhere subq.\u201d systemic whole-body circulating", "legal_class": null }, { "id": 6, "slug": "cjc-1295-ipamorelin", "name": "CJC-1295 / Ipamorelin (blend discussion)", "aliases": [ "CJC Ipamorelin", "CJC/IPA", "CJC-1295 no DAC + Ipamorelin", "CJC IPA blend", "Mod GRF 1-29 + Ipamorelin", "CJC-1295/Ipamorelin", "CJC + Ipa", "CJC1295 Ipamorelin stack", "GHRH + GHS blend (CJC/IPA)", "CJC no DAC / IPA", "Mod GRF + Ipamorelin", "CJC IPA 5/5", "CJC-1295 Ipam" ], "type": "Peptide", "category": "Growth hormone axis", "goals_use_cases": [ "muscle growth", "recovery", "sleep", "fat loss", "performance", "muscle growth / lean mass (discussed)", "recovery / training readiness", "sleep quality / depth", "fat loss / recomp assist (discussed)", "performance continuity", "body composition", "anti-aging / wellness clinic use (discussed)", "IGF-1 support / lab proxy (discussed)", "skin / collagen / fullness talk", "joint / soft-tissue comfort (discussed)", "lean-mass support during GLP-1 cuts (discussed)", "TRT-adjacent men\u2019s-health layering (discussed)" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "cjc-1295-ipamorelin", "cjc 1295 ipamorelin", "cjc1295ipamorelin", "CJC-1295 / Ipamorelin (blend discussion)", "cjc-1295-/-ipamorelin-(blend-discussion)", "CJC Ipamorelin", "sleep", "deep sleep", "recovery", "hunger", "vivid dreams", "empty stomach", "compounding", "IGF-1", "carpal", "DAC", "reconstitution", "split dose", "research use only" ], "feel_search": [ "sleep", "deep sleep", "recovery", "hunger", "vivid dreams", "empty stomach", "compounding", "IGF-1", "carpal", "DAC", "reconstitution", "split dose", "research use only" ], "summary": "CJC/IPA usually means short-acting Mod GRF 1-29, called CJC no DAC, combined with ipamorelin to stimulate growth-hormone release.", "search_blob": "cjc-1295 / ipamorelin (blend discussion) cjc-1295-ipamorelin cjc ipamorelin cjc/ipa cjc-1295 no dac + ipamorelin cjc ipa blend mod grf 1-29 + ipamorelin cjc-1295/ipamorelin cjc + ipa cjc1295 ipamorelin stack ghrh + ghs blend (cjc/ipa) cjc no dac / ipa mod grf + ipamorelin cjc ipa 5/5 cjc-1295 ipam cjc-1295-ipamorelin cjc 1295 ipamorelin cjc1295ipamorelin cjc-1295 / ipamorelin (blend discussion) cjc-1295-/-ipamorelin-(blend-discussion) cjc ipamorelin sleep deep sleep recovery hunger vivid dreams empty stomach compounding igf-1 carpal dac reconstitution split dose research use only muscle growth recovery sleep fat loss performance muscle growth / lean mass (discussed) recovery / training readiness sleep quality / depth fat loss / recomp assist (discussed) performance continuity body composition anti-aging / wellness clinic use (discussed) igf-1 support / lab proxy (discussed) skin / collagen / fullness talk joint / soft-tissue comfort (discussed) lean-mass support during glp-1 cuts (discussed) trt-adjacent men\u2019s-health layering (discussed) sleep deep sleep recovery hunger vivid dreams empty stomach compounding igf-1 carpal dac reconstitution split dose research use only cjc/ipa usually means short-acting mod grf 1-29, called cjc no dac, combined with ipamorelin to stimulate growth-hormone release. one user reports poor sleep after a missed dose; another reports good sleep even on off-days. vivid dreams occur in some accounts, so dependence is not established. cjc/ipa is a peptide blend people look up for sleep and recovery. bedtime drowsiness, warmer sleep, or vivid dreams are the usual first signals when dosed pre-bed fasted. almost always two short-acting shots (no-dac cjc + ipamorelin), often at night on an empty stomach. growth hormone axis peptide systemic systemic \u2014 a ghrh analog plus a ghrelin-receptor agonist, discussed for whole-body sleep, recovery and composition rather than local tissue repair. systemic whole-body circulating", "legal_class": null }, { "id": 7, "slug": "ipamorelin", "name": "Ipamorelin", "aliases": [ "IPA", "NNC 26-0161", "Ipam", "NNC26-0161", "NNC 260161", "Aib-His-D-2-Nal-D-Phe-Lys-NH2", "Ipamorelin acetate", "Ipamorelin acetate salt", "selective GHRP", "third-generation GHRP (community label)" ], "type": "Peptide", "category": "Growth hormone axis", "goals_use_cases": [ "muscle growth", "recovery", "sleep", "anti-aging discussion", "muscle growth / lean mass (discussed)", "recovery / training continuity", "sleep depth and fall-asleep ease", "anti-aging / wellness clinic discussion", "body recomposition", "performance / work capacity feel", "fat loss adjacency (via GH/IGF talk, not a fat burner)", "injury-season recovery adjacency", "IGF-1 support / axis engagement (discussed)", "lean recomp without GHRP-6-level hunger", "selective GHRP alternative to GHRP-2 / GHRP-6 / hexarelin", "dual-pulse stack with GHRH (CJC no-DAC / Mod GRF)" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "ipamorelin", "IPA", "Ipam", "NNC 26-0161", "NNC26-0161", "NNC 260161", "sleep", "recovery", "hunger", "gh pulse", "empty stomach", "compounding", "IGF-1", "carpal", "reconstitution", "split dose", "research use only" ], "feel_search": [ "sleep", "recovery", "hunger", "gh pulse", "empty stomach", "compounding", "IGF-1", "carpal", "reconstitution", "split dose", "research use only" ], "summary": "Ipamorelin is a synthetic peptide that stimulates growth-hormone release through the ghrelin receptor, discussed for sleep and recovery.", "search_blob": "ipamorelin ipamorelin ipa nnc 26-0161 ipam nnc26-0161 nnc 260161 aib-his-d-2-nal-d-phe-lys-nh2 ipamorelin acetate ipamorelin acetate salt selective ghrp third-generation ghrp (community label) ipamorelin ipa ipam nnc 26-0161 nnc26-0161 nnc 260161 sleep recovery hunger gh pulse empty stomach compounding igf-1 carpal reconstitution split dose research use only muscle growth recovery sleep anti-aging discussion muscle growth / lean mass (discussed) recovery / training continuity sleep depth and fall-asleep ease anti-aging / wellness clinic discussion body recomposition performance / work capacity feel fat loss adjacency (via gh/igf talk, not a fat burner) injury-season recovery adjacency igf-1 support / axis engagement (discussed) lean recomp without ghrp-6-level hunger selective ghrp alternative to ghrp-2 / ghrp-6 / hexarelin dual-pulse stack with ghrh (cjc no-dac / mod grf) sleep recovery hunger gh pulse empty stomach compounding igf-1 carpal reconstitution split dose research use only ipamorelin is a synthetic peptide that stimulates growth-hormone release through the ghrelin receptor, discussed for sleep and recovery. standalone accounts vary: one user noticed deeper sleep within days, another no change after two weeks, and another fatigue and increased appetite. a hormone-release effect need not produce a noticeable feeling. ipamorelin is a peptide people look up for sleep and recovery. \u201cclean\u201d ghrp pulse for sleep/recovery \u2014 usually stacked with a ghrh analog, not run alone forever. people like it because hunger and cortisol talk is quieter than older ghrps. night pin is the simple version. growth hormone axis peptide systemic systemic ghrelin-receptor agonist discussed for gh pulses, sleep and recovery; not a targeted joint treatment. systemic whole-body circulating", "legal_class": null }, { "id": 8, "slug": "cjc-1295", "name": "CJC-1295", "aliases": [ "CJC-1295 with DAC", "CJC-1295 no DAC", "Mod GRF adjacency", "CJC-1295 without DAC", "Mod GRF 1-29", "Modified GRF 1-29", "DAC:GRF", "DAC:GRF (ConjuChem)", "CJC1295", "CJC 1295", "CJC-1295 DAC", "tetrasubstituted GRF 1-29" ], "type": "Peptide", "category": "Growth hormone axis", "goals_use_cases": [ "muscle growth", "recovery", "fat loss", "sleep", "performance", "body recomposition", "anti-aging (discussed)", "IGF-1 support (discussed)", "lean mass preservation", "skin / recovery adjacency" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "cjc-1295", "cjc 1295", "cjc1295", "CJC-1295 with DAC", "CJC-1295 no DAC", "CJC-1295 without DAC", "sleep", "water retention", "recovery", "empty stomach", "compounding", "IGF-1", "carpal", "DAC", "no-DAC", "reconstitution", "split dose" ], "feel_search": [ "sleep", "water retention", "recovery", "empty stomach", "compounding", "IGF-1", "carpal", "DAC", "no-DAC", "reconstitution", "split dose" ], "summary": "CJC-1295 is a growth-hormone-releasing-hormone analogue; the name is also used for no-DAC Mod GRF 1-29, a different short-acting product.", "search_blob": "cjc-1295 cjc-1295 cjc-1295 with dac cjc-1295 no dac mod grf adjacency cjc-1295 without dac mod grf 1-29 modified grf 1-29 dac:grf dac:grf (conjuchem) cjc1295 cjc 1295 cjc-1295 dac tetrasubstituted grf 1-29 cjc-1295 cjc 1295 cjc1295 cjc-1295 with dac cjc-1295 no dac cjc-1295 without dac sleep water retention recovery empty stomach compounding igf-1 carpal dac no-dac reconstitution split dose muscle growth recovery fat loss sleep performance body recomposition anti-aging (discussed) igf-1 support (discussed) lean mass preservation skin / recovery adjacency sleep water retention recovery empty stomach compounding igf-1 carpal dac no-dac reconstitution split dose cjc-1295 is a growth-hormone-releasing-hormone analogue; the name is also used for no-dac mod grf 1-29, a different short-acting product. a user adding no-dac cjc to ipamorelin describes a head rush within minutes. that immediate feeling does not establish muscle growth or long-term benefit. cjc-1295 is a peptide people look up for muscle. vivid dreams: common early signal when dosing pre-bed; used as a crude \u201cit landed\u201d marker. sleep is the first story on the short version. the long version has more water / side lore. growth hormone axis peptide systemic systemic \u2014 raises circulating gh/igf-1 via pituitary ghrh-receptor stimulation; not a local inject-site healing peptide. systemic whole-body circulating", "legal_class": null }, { "id": 9, "slug": "mk-677", "name": "MK-677", "aliases": [ "Ibutamoren", "Ibutamoren mesylate", "Nutrobal", "MK-0677", "MK0677", "L-163,191", "LUM-201", "Oratrope (former tentative brand)", "MK677", "MK 677" ], "type": "Non-peptide", "category": "Growth hormone axis", "goals_use_cases": [ "muscle growth", "sleep", "appetite", "recovery", "bone discussion", "muscle growth / lean mass (discussed; water + FFM mix)", "sleep quality (slow-wave / REM \u2014 trial-anchored)", "appetite / hard-gainer bulk", "recovery / training continuity", "IGF-1 elevation (discussed / lab-tracked)", "anti-catabolism during deficit (Murphy nitrogen talk)", "body recomposition (discussed; confounded by calories + water)", "bone turnover / density discussion (older-adult / osteoporosis trials)", "oral GH-axis alternative to injectables", "skin / fullness look (anecdotal)", "performance continuity (non-tested athletes \u2014 WADA banned)", "pediatric GHD research (LUM-201 program \u2014 separate clinical path)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "mk-677", "mk 677", "mk677", "Ibutamoren", "Ibutamoren mesylate", "MK-0677", "hunger", "sleep", "water retention", "bloated", "IGF-1", "glucose", "compounding", "research chemical", "ibutamoren" ], "feel_search": [ "hunger", "sleep", "water retention", "bloated", "ibutamoren", "IGF-1", "glucose", "compounding", "research chemical" ], "summary": "MK-677 (ibutamoren) is an oral ghrelin-receptor agonist that stimulates growth hormone; people seek appetite, sleep and fullness effects.", "search_blob": "mk-677 mk-677 ibutamoren ibutamoren mesylate nutrobal mk-0677 mk0677 l-163,191 lum-201 oratrope (former tentative brand) mk677 mk 677 mk-677 mk 677 mk677 ibutamoren ibutamoren mesylate mk-0677 hunger sleep water retention bloated igf-1 glucose compounding research chemical ibutamoren muscle growth sleep appetite recovery bone discussion muscle growth / lean mass (discussed; water + ffm mix) sleep quality (slow-wave / rem \u2014 trial-anchored) appetite / hard-gainer bulk recovery / training continuity igf-1 elevation (discussed / lab-tracked) anti-catabolism during deficit (murphy nitrogen talk) body recomposition (discussed; confounded by calories + water) bone turnover / density discussion (older-adult / osteoporosis trials) oral gh-axis alternative to injectables skin / fullness look (anecdotal) performance continuity (non-tested athletes \u2014 wada banned) pediatric ghd research (lum-201 program \u2014 separate clinical path) hunger sleep water retention bloated ibutamoren igf-1 glucose compounding research chemical mk-677 (ibutamoren) is an oral ghrelin-receptor agonist that stimulates growth hormone; people seek appetite, sleep and fullness effects. hunger and sleep changes are often noticed early. some report deeper sleep; others describe grogginess, water retention or tingling, and the strength of the effect varies. mk-677 is an oral compound people take for hunger, sleep, and muscle. nights 1\u201314 are ravenous + deep sleep. the hunger can wreck a cut. water and morning glucose talk is loud. 25 mg is the study number people copy. growth hormone axis non-peptide systemic systemic \u2014 oral non-peptide ghrelin-receptor (ghs-r1a) agonist / gh secretagogue; whole-body gh pulses and circulating igf-1, not local site targeting. systemic whole-body circulating", "legal_class": null }, { "id": 10, "slug": "ghk-cu", "name": "GHK-Cu", "aliases": [ "Copper peptide", "GHK copper", "glycyl-L-histidyl-L-lysine copper", "GHK-Cu copper tripeptide", "copper tripeptide-1 (cosmetic INCI contexts)", "Gly-His-Lys-Cu", "copper tripeptide-1" ], "type": "Peptide", "category": "Skin, hair & tissue remodeling", "goals_use_cases": [ "skin/hair", "recovery", "anti-aging discussion", "wound narratives", "collagen / firmness talk", "aesthetic remodeling", "longevity discussion", "scar / texture narratives", "post-procedure recovery talk", "Glow / KLOW stack component" ], "delivery_methods": [ "topical", "subcutaneous", "microneedling adjacency" ], "discussion_popularity": "High", "reach": "Mixed", "misspellings_search_terms": [ "ghk-cu", "ghk cu", "ghkcu", "Copper peptide", "GHK copper", "glycyl-L-histidyl-L-lysine copper", "skin", "hair", "wrinkles", "sting", "glow", "pcac", "503a", "compounding", "copper uglies", "after shower", "injectable ghk", "blue sting" ], "feel_search": [ "skin", "hair", "wrinkles", "sting", "glow", "copper uglies", "blue sting", "after shower" ], "summary": "GHK-Cu is a copper-binding peptide used in skin products and discussed in injection logs for skin and hair changes.", "search_blob": "ghk-cu ghk-cu copper peptide ghk copper glycyl-l-histidyl-l-lysine copper ghk-cu copper tripeptide copper tripeptide-1 (cosmetic inci contexts) gly-his-lys-cu copper tripeptide-1 ghk-cu ghk cu ghkcu copper peptide ghk copper glycyl-l-histidyl-l-lysine copper skin hair wrinkles sting glow pcac 503a compounding copper uglies after shower injectable ghk blue sting skin/hair recovery anti-aging discussion wound narratives collagen / firmness talk aesthetic remodeling longevity discussion scar / texture narratives post-procedure recovery talk glow / klow stack component skin hair wrinkles sting glow copper uglies blue sting after shower ghk-cu is a copper-binding peptide used in skin products and discussed in injection logs for skin and hair changes. ghk-cu is a peptide people look up for skin. firmer, smoother skin and fine-line talk over multi-week consistent use; photo reassess common at 8\u201312 weeks. the pin often stings. skin talk is weeks, not overnight. shower then serum for topical; don\u2019t mix that up with the injectable, and don\u2019t file ghk under the july 2026 bpc/tb compounding vote. skin, hair & tissue remodeling peptide mixed mixed \u2014 topical stays on skin/scalp; injectable charts treat it as whole-body remodeling. mixed local systemic", "legal_class": null }, { "id": 11, "slug": "melanotan-ii", "name": "Melanotan II", "aliases": [ "MT2", "MT-II", "Melanotan 2", "Melanotan-II", "MT-2", "MT II", "Barbie drug", "tan jab", "Ac-Nle-c[Asp-His-D-Phe-Arg-Trp-Lys]-NH2", "Ac-Nle4-Asp5-His6-D-Phe7-Arg8-Trp9-Lys10-\u03b1-MSH4-10-NH2" ], "type": "Peptide", "category": "Tanning & melanocortin", "goals_use_cases": [ "skin/hair", "libido", "appetite (discussed)", "tanning / pigmentation", "sunless / UV-assisted bronze", "nasal tanning spray interest", "libido / sexual arousal (discussed)", "erectile response (historical clinical discussion)", "appetite suppression (discussed)", "aesthetic bodybuilding / gym culture tan", "competition prep / stage color (discussed)", "photoprotection narrative (discussed, not proven protection)", "pre-vacation / seasonal tan runs" ], "delivery_methods": [ "subcutaneous", "nasal" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "melanotan-ii", "melanotan ii", "melanotanii", "MT2", "MT-II", "Melanotan 2", "tan", "nausea", "libido", "freckles", "barbie", "loading", "pt-141" ], "feel_search": [ "tan", "nausea", "libido", "freckles", "barbie", "loading", "pt-141" ], "summary": "Melanotan II is an experimental cyclic alpha-MSH analog used in tanning culture, with pigmentation, appetite and sexual-effect discussion.", "search_blob": "melanotan ii melanotan-ii mt2 mt-ii melanotan 2 melanotan-ii mt-2 mt ii barbie drug tan jab ac-nle-c[asp-his-d-phe-arg-trp-lys]-nh2 ac-nle4-asp5-his6-d-phe7-arg8-trp9-lys10-\u03b1-msh4-10-nh2 melanotan-ii melanotan ii melanotanii mt2 mt-ii melanotan 2 tan nausea libido freckles barbie loading pt-141 skin/hair libido appetite (discussed) tanning / pigmentation sunless / uv-assisted bronze nasal tanning spray interest libido / sexual arousal (discussed) erectile response (historical clinical discussion) appetite suppression (discussed) aesthetic bodybuilding / gym culture tan competition prep / stage color (discussed) photoprotection narrative (discussed, not proven protection) pre-vacation / seasonal tan runs tan nausea libido freckles barbie loading pt-141 melanotan ii is an experimental cyclic alpha-msh analog used in tanning culture, with pigmentation, appetite and sexual-effect discussion. reports include flushing and prolonged spontaneous erections as well as gradual pigment changes. one three-week tanning account said it felt side-effect-free but also described new freckles and sunbed use. melanotan ii is a peptide for tanning. community claim is deeper color with less sunbed/outdoor time than uv alone; habits, baseline phototype, and product fill confound every log. freckles and moles often darken first. nausea is the limiter, not the tan. tanning & melanocortin peptide systemic systemic melanocortin agonist discussed for pigmentation, appetite and arousal; community products are unapproved injections or nasal sprays. systemic whole-body circulating", "legal_class": null }, { "id": 12, "slug": "pt-141", "name": "PT-141", "aliases": [ "Bremelanotide", "Vyleesi", "PT141", "PT 141", "Bremelanotide acetate", "BMT", "Bremelanotide injection" ], "type": "Peptide", "category": "Libido & melanocortin", "goals_use_cases": [ "libido", "sexual function", "libido / sexual desire (central)", "sexual function / arousal signaling", "HSDD \u2014 FDA-approved Vyleesi context (acquired, generalized; premenopausal women)", "desire / mental arousal (CNS melanocortin, not genital vasodilator)", "ED and PDE5 non-responders (historical IN trial + off-label clinic discussion)", "low desire in men (off-label clinic and forum talk \u2014 not FDA-indicated)", "psychogenic / performance-anxiety-adjacent desire talk", "PDE5 incomplete responders seeking \u2018want\u2019 + hardness (stack discussion)", "CNS sexual signaling research (MC4R/MC3R emphasis)", "as-needed PRN date-night pharmacology (not daily hormone replacement)" ], "delivery_methods": [ "subcutaneous", "nasal" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "pt-141", "pt 141", "pt141", "Bremelanotide", "Vyleesi", "Bremelanotide acetate", "libido", "desire", "nausea", "sex", "vyleesi", "zofran", "melanotan" ], "feel_search": [ "libido", "desire", "nausea", "vyleesi", "sex", "zofran", "melanotan" ], "summary": "PT-141, or bremelanotide, is a synthetic melanocortin-receptor peptide discussed for sexual desire; the medical product is an injection.", "search_blob": "pt-141 pt-141 bremelanotide vyleesi pt141 pt 141 bremelanotide acetate bmt bremelanotide injection pt-141 pt 141 pt141 bremelanotide vyleesi bremelanotide acetate libido desire nausea sex vyleesi zofran melanotan libido sexual function libido / sexual desire (central) sexual function / arousal signaling hsdd \u2014 fda-approved vyleesi context (acquired, generalized; premenopausal women) desire / mental arousal (cns melanocortin, not genital vasodilator) ed and pde5 non-responders (historical in trial + off-label clinic discussion) low desire in men (off-label clinic and forum talk \u2014 not fda-indicated) psychogenic / performance-anxiety-adjacent desire talk pde5 incomplete responders seeking \u2018want\u2019 + hardness (stack discussion) cns sexual signaling research (mc4r/mc3r emphasis) as-needed prn date-night pharmacology (not daily hormone replacement) libido desire nausea vyleesi sex zofran melanotan pt-141, or bremelanotide, is a synthetic melanocortin-receptor peptide discussed for sexual desire; the medical product is an injection. reports range from flushing without the desired effect to strong sexual response or severe nausea; one couple reported very different reactions. pt-141 is a peptide people look up for libido. many describe clear yes/no after a few spaced uses \u2014 stop if no meaningful benefit rather than endless dose chasing. nausea is the famous side. label is 1.75 mg; some people talk lower first. libido & melanocortin peptide systemic systemic cns melanocortin agonist; desire/arousal signaling is central, while pigmentation and blood-pressure effects are systemic. systemic whole-body circulating", "legal_class": null }, { "id": 13, "slug": "aod-9604", "name": "AOD-9604", "aliases": [ "AOD 9604", "hGH Fragment 176-191 related marketing", "lipolytic fragment peptide", "AOD9604", "Tyr-hGH177-191", "Tyr-hGH 177-191", "Anti-Obesity Drug 9604", "hexadecapeptide 177-191", "C-terminal hGH fragment analog", "sh-Oligopeptide-74 (INCI-style naming in some safety write-ups)" ], "type": "Peptide", "category": "Metabolic / fat-loss peptides", "goals_use_cases": [ "fat loss", "body recomposition", "lipolysis support (discussed)", "lipogenesis inhibition (preclinical claim)", "abdominal / stubborn fat reduction (discussed)", "GH-like fat metabolism without IGF-1 rise (claimed)", "metabolic research", "cutting phase adjunct (community)", "performance continuity while leaning", "joint / cartilage research interest (animal IA data)", "GLP-1 stack polish without more appetite suppression (community)", "appetite-neutral fat-path adjunct vs satiety drugs (community framing)" ], "delivery_methods": [ "subcutaneous", "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "aod-9604", "aod 9604", "aod9604", "Tyr-hGH177-191", "Tyr-hGH 177-191", "hGH Fragment 176-191 related marketing", "stubborn fat", "waist", "fasted", "cut", "disappointed", "gel" ], "feel_search": [ "stubborn fat", "waist", "fasted", "cut", "disappointed", "gel" ], "summary": "AOD-9604 is a modified growth-hormone fragment investigated for fat loss, distinct from full growth hormone.", "search_blob": "aod-9604 aod-9604 aod 9604 hgh fragment 176-191 related marketing lipolytic fragment peptide aod9604 tyr-hgh177-191 tyr-hgh 177-191 anti-obesity drug 9604 hexadecapeptide 177-191 c-terminal hgh fragment analog sh-oligopeptide-74 (inci-style naming in some safety write-ups) aod-9604 aod 9604 aod9604 tyr-hgh177-191 tyr-hgh 177-191 hgh fragment 176-191 related marketing stubborn fat waist fasted cut disappointed gel fat loss body recomposition lipolysis support (discussed) lipogenesis inhibition (preclinical claim) abdominal / stubborn fat reduction (discussed) gh-like fat metabolism without igf-1 rise (claimed) metabolic research cutting phase adjunct (community) performance continuity while leaning joint / cartilage research interest (animal ia data) glp-1 stack polish without more appetite suppression (community) appetite-neutral fat-path adjunct vs satiety drugs (community framing) stubborn fat waist fasted cut disappointed gel aod-9604 is a modified growth-hormone fragment investigated for fat loss, distinct from full growth hormone. reports conflict: one person saw no change after seven weeks alongside ozempic; others claim waist changes while also using glp-1 drugs, dieting or training. aod-9604 is a peptide people look up for fat loss. modest help only when diet and training already dialed; small, confounded logs dominate; not a \u201cdump\u201d peptide. people often pin it fasted in the morning. not a miracle waist shot. metabolic / fat-loss peptides peptide systemic systemic fat-loss fragment claims, usually subq in community reports; not proven spot reduction or equivalent to oral trial dosing. systemic whole-body circulating", "legal_class": null }, { "id": 15, "slug": "tesamorelin", "name": "Tesamorelin", "aliases": [ "Egrifta", "TH9507", "Egrifta SV", "Egrifta WR", "TH-9507", "Tesamorelin acetate", "GHRH analog (trans-3-hexenoyl)" ], "type": "Peptide", "category": "Growth hormone axis", "goals_use_cases": [ "fat loss", "visceral fat discussion", "muscle preservation", "body recomposition", "metabolic health (discussed)", "liver fat / NAFLD adjacency (HIV trial data)", "HIV lipodystrophy context", "IGF-1 support (discussed)", "waist / midsection aesthetics", "GH-axis alternative to exogenous HGH" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "tesamorelin", "Egrifta", "Egrifta SV", "Egrifta WR", "TH9507", "TH-9507", "belly fat", "visceral fat", "vat", "water retention", "itch", "hives", "pinchable", "compounding", "research use only" ], "feel_search": [ "belly fat", "visceral fat", "vat", "water retention", "itch", "hives", "pinchable", "compounding", "research use only" ], "summary": "Tesamorelin is a synthetic GHRH analogue that stimulates pituitary growth-hormone release, discussed for visceral-fat reduction.", "search_blob": "tesamorelin tesamorelin egrifta th9507 egrifta sv egrifta wr th-9507 tesamorelin acetate ghrh analog (trans-3-hexenoyl) tesamorelin egrifta egrifta sv egrifta wr th9507 th-9507 belly fat visceral fat vat water retention itch hives pinchable compounding research use only fat loss visceral fat discussion muscle preservation body recomposition metabolic health (discussed) liver fat / nafld adjacency (hiv trial data) hiv lipodystrophy context igf-1 support (discussed) waist / midsection aesthetics gh-axis alternative to exogenous hgh belly fat visceral fat vat water retention itch hives pinchable compounding research use only tesamorelin is a synthetic ghrh analogue that stimulates pituitary growth-hormone release, discussed for visceral-fat reduction. several commenters reported fragmented sleep; one also mentioned palpitations, despite expecting sleep to improve. tesamorelin is a peptide people look up for fat loss. scale may barely move while ct/mri vat improves. community accounts discuss 1\u20132 mg sc daily. the original trial product used 2 mg; current sv uses 1.4 mg and wr 1.28 mg. these formulations are not interchangeable. growth hormone axis peptide systemic whole-body gh-axis \u2014 not a local fat-dissolve pin. systemic whole-body circulating", "legal_class": null }, { "id": 16, "slug": "sermorelin", "name": "Sermorelin", "aliases": [ "GHRH 1-29", "GRF 1-29", "Sermorelin acetate", "GHRH (1-29)", "GHRH (1-29) NH2", "GRF 1\u201329", "GRF 1-29 NH2", "Geref (historical brand)", "Geref Diagnostic (historical brand)", "Sermorelin acetate injection" ], "type": "Peptide", "category": "Growth hormone axis", "goals_use_cases": [ "anti-aging discussion", "sleep", "recovery", "muscle growth", "body composition", "IGF-1 support (discussed)", "performance continuity", "longevity clinic protocols", "pituitary GH stimulation (discussed)", "lean recomp (discussed)", "skin thickness / wellness talk", "age-related GH decline discussion" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "sermorelin", "Sermorelin acetate", "GHRH 1-29", "GHRH (1-29)", "GHRH (1-29) NH2", "GRF 1-29", "sleep", "anti-aging", "recovery", "empty stomach", "compounding", "IGF-1", "carpal", "Geref", "split dose" ], "feel_search": [ "sleep", "anti-aging", "recovery", "empty stomach", "compounding", "IGF-1", "carpal", "Geref", "split dose" ], "summary": "Sermorelin is a synthetic 29-amino-acid fragment of growth-hormone-releasing hormone (GHRH), used to stimulate pituitary GH release.", "search_blob": "sermorelin sermorelin ghrh 1-29 grf 1-29 sermorelin acetate ghrh (1-29) ghrh (1-29) nh2 grf 1\u201329 grf 1-29 nh2 geref (historical brand) geref diagnostic (historical brand) sermorelin acetate injection sermorelin sermorelin acetate ghrh 1-29 ghrh (1-29) ghrh (1-29) nh2 grf 1-29 sleep anti-aging recovery empty stomach compounding igf-1 carpal geref split dose anti-aging discussion sleep recovery muscle growth body composition igf-1 support (discussed) performance continuity longevity clinic protocols pituitary gh stimulation (discussed) lean recomp (discussed) skin thickness / wellness talk age-related gh decline discussion sleep anti-aging recovery empty stomach compounding igf-1 carpal geref split dose sermorelin is a synthetic 29-amino-acid fragment of growth-hormone-releasing hormone (ghrh), used to stimulate pituitary gh release. one user described vivid dreams and better recovery; another said sleep worsened and improved during a break. sermorelin, whose historical geref also contained sermorelin acetate, is a peptide people look up for sleep. fed pins get the same \u201cwhy am i awake\u201d posts as other ghrh shots. clinic wellness favorite. quieter than mk-677 hunger talk. growth hormone axis peptide systemic systemic \u2014 short-acting ghrh(1-29) fragment that pulses pituitary gh release; downstream igf-1 and whole-body recovery/sleep/body-comp effects. systemic whole-body circulating", "legal_class": null }, { "id": 17, "slug": "igf-1-lr3", "name": "IGF-1 LR3", "aliases": [ "Long R3 IGF-1", "IGF1 LR3", "IGF-1", "Long Arg3 IGF-1", "Long-R3-IGF-I", "LONG\u00ae R\u00b3 IGF-I (cell-culture reagent class)", "IGF-1 Long R3", "LR3 IGF-1", "LR3-IGF-1", "Long arginine 3-IGF-1" ], "type": "Peptide", "category": "Growth factors", "goals_use_cases": [ "muscle growth", "performance", "recovery", "muscle growth / hypertrophy (discussed)", "recovery / training continuity (discussed)", "body recomposition (discussed)", "site-enhancement / regional fullness discussion", "anti-catabolism (discussed)", "nutrient partitioning (discussed)", "satellite-cell / hyperplasia talk (community + preclinical framing)", "GH-axis \u201cdirect receptor\u201d alternative to HGH or secretagogues", "cell-culture / research-reagent context (industrial LONG R3 IGF-I)" ], "delivery_methods": [ "intramuscular", "subcutaneous" ], "discussion_popularity": "High", "reach": "Mixed", "misspellings_search_terms": [ "igf-1-lr3", "igf 1 lr3", "igf1lr3", "IGF-1 LR3", "Long R3 IGF-1", "Long Arg3 IGF-1", "pumps", "hypoglycemia", "shaky", "size", "fullness", "with food", "compounding", "IGF-1", "acetic acid", "glucose" ], "feel_search": [ "pumps", "hypoglycemia", "shaky", "size", "fullness", "with food", "compounding", "IGF-1", "acetic acid", "glucose" ], "summary": "IGF-1 LR3 is a modified IGF-1 research peptide, discussed for muscle fullness and growth; it is distinct from HGH and from IGF-1 DES.", "search_blob": "igf-1 lr3 igf-1-lr3 long r3 igf-1 igf1 lr3 igf-1 long arg3 igf-1 long-r3-igf-i long\u00ae r\u00b3 igf-i (cell-culture reagent class) igf-1 long r3 lr3 igf-1 lr3-igf-1 long arginine 3-igf-1 igf-1-lr3 igf 1 lr3 igf1lr3 igf-1 lr3 long r3 igf-1 long arg3 igf-1 pumps hypoglycemia shaky size fullness with food compounding igf-1 acetic acid glucose muscle growth performance recovery muscle growth / hypertrophy (discussed) recovery / training continuity (discussed) body recomposition (discussed) site-enhancement / regional fullness discussion anti-catabolism (discussed) nutrient partitioning (discussed) satellite-cell / hyperplasia talk (community + preclinical framing) gh-axis \u201cdirect receptor\u201d alternative to hgh or secretagogues cell-culture / research-reagent context (industrial long r3 igf-i) pumps hypoglycemia shaky size fullness with food compounding igf-1 acetic acid glucose igf-1 lr3 is a modified igf-1 research peptide, discussed for muscle fullness and growth; it is distinct from hgh and from igf-1 des. one six-week report describes modest early pumps, later endurance and fullness, plus water retention, sore hands and tingling. diet, training and tesofensine were part of the same period. igf-1 lr3 is a peptide people look up for muscle. subjective size/fullness claims most often land here when they land; not a steroid-like overnight flip. not a beginner peptide in careful threads. food around the pin is part of the lore. growth factors peptide mixed mixed \u2014 subq is the systemic forum default; im site use is debated, and no human lr3 half-life establishes long or local exposure. mixed local systemic", "legal_class": null }, { "id": 18, "slug": "epitalon", "name": "Epitalon", "aliases": [ "Epithalon", "Epithalone", "AEDG peptide", "AEDG", "Ala-Glu-Asp-Gly", "AlaGluAspGly", "Epithalamin (related pineal extract; not identical)", "Epithalamine (spelling variant of the extract)", "Khavinson pineal tetrapeptide", "CAS 307297-39-8" ], "type": "Peptide", "category": "Longevity & bioregulators", "goals_use_cases": [ "longevity", "sleep", "anti-aging discussion", "telomere / cellular aging narratives", "telomerase (hTERT) activation talk", "circadian / melatonin talk", "pineal bioregulator interest", "recovery continuity (discussed)", "immune aging discussion (minority)", "geroprotection / mortality-cohort talk (historical Russian literature)", "antioxidant / DNA-damage narratives", "vs TA-65 oral telomerase-class comparison", "vs epithalamin extract identity / dosing debate", "yearly bioregulator course calendars" ], "delivery_methods": [ "subcutaneous", "nasal" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "epitalon", "Epithalon", "Epithalone", "AEDG", "AEDG peptide", "Ala-Glu-Asp-Gly", "sleep", "longevity", "telomere", "pineal", "pcac", "10 day" ], "feel_search": [ "sleep", "longevity", "telomere", "pineal", "pcac", "10 day" ], "summary": "Epitalon is a synthetic four-amino-acid peptide discussed for sleep and longevity. Often cited as the sleep/circadian rationale for synthetic courses.", "search_blob": "epitalon epitalon epithalon epithalone aedg peptide aedg ala-glu-asp-gly alagluaspgly epithalamin (related pineal extract; not identical) epithalamine (spelling variant of the extract) khavinson pineal tetrapeptide cas 307297-39-8 epitalon epithalon epithalone aedg aedg peptide ala-glu-asp-gly sleep longevity telomere pineal pcac 10 day longevity sleep anti-aging discussion telomere / cellular aging narratives telomerase (htert) activation talk circadian / melatonin talk pineal bioregulator interest recovery continuity (discussed) immune aging discussion (minority) geroprotection / mortality-cohort talk (historical russian literature) antioxidant / dna-damage narratives vs ta-65 oral telomerase-class comparison vs epithalamin extract identity / dosing debate yearly bioregulator course calendars sleep longevity telomere pineal pcac 10 day epitalon is a synthetic four-amino-acid peptide discussed for sleep and longevity. often cited as the sleep/circadian rationale for synthetic courses. one insomnia writer reports better sleep during and soon after a course, then later says the benefit stopped within weeks. a later mixed product is a separate experience. epitalon is a synthetic four-amino-acid peptide discussed for sleep and longevity. often cited as the sleep/circadian rationale for synthetic courses. two different worlds: short high-mg vial courses vs longer lower-mg charts. don\u2019t mix extract (epithalamin) with this. longevity & bioregulators peptide systemic systemic \u2014 pineal/telomere longevity peptide; not a local injury-site agent. systemic whole-body circulating", "legal_class": null }, { "id": 19, "slug": "semax", "name": "Semax", "aliases": [ "Met-Glu-His-Phe-Pro-Gly-Pro", "N-Acetyl Semax (related)", "MEHFPGP", "H-MEHFPGP-OH", "ACTH(4-7)-PGP", "(Pro8,Gly9,Pro10)ACTH-(4-10)", "ACTH(4-10) analog (heptapeptide shorthand)", "Semax 0.1%", "Semax 1%", "Semax-Hept (1% product talk)", "SEMAX\u00ae (Russian pharmacy brand discussions)", "\u0421\u0435\u043c\u0430\u043a\u0441", "N-Acetyl Semax (related analog \u2014 not identical)", "N-Acetyl Semax Amidate / NASA (related analog \u2014 not identical)", "CAS 80714-61-0 (primary registry discussions)", "MW ~813.93 g/mol (C37H51N9O10S)" ], "type": "Peptide", "category": "Cognitive / nootropic peptides", "goals_use_cases": [ "cognition", "focus", "neuroprotection discussion", "mood", "attention", "working memory (discussed)", "memory / learning support (discussed)", "mental performance under load or fatigue", "stroke / cerebrovascular recovery discussion (Russian clinical history)", "transient ischemic attack discussion (product history)", "optic-nerve / visual-pathway discussion (Russian clinical history)", "mood / stress resilience (mild; secondary to focus for many)", "ADHD-adjacent focus talk (community only; not an approved indication)", "exam / deep-work / high-cognitive-load sprints", "nootropic stacking (classically with Selank)", "peptic-ulcer adjunct discussion (Russian product history \u2014 not Western nootropic use)", "alcohol-delirium / post-toxic cognitive recovery discussion (Russian clinical series)" ], "delivery_methods": [ "nasal", "subcutaneous" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "semax", "Met-Glu-His-Phe-Pro-Gly-Pro", "MEHFPGP", "H-MEHFPGP-OH", "ACTH(4-7)-PGP", "(Pro8,Gly9,Pro10)ACTH-(4-10)", "focus", "brain fog", "exam", "attention", "nasal", "word finding", "anxiety", "insomnia", "hair loss", "hair shedding" ], "feel_search": [ "focus", "brain fog", "exam", "attention", "nasal", "word finding", "anxiety", "insomnia", "hair loss", "hair shedding" ], "summary": "Semax is a synthetic seven-amino-acid peptide derived from an ACTH fragment, discussed for focus and cognitive function.", "search_blob": "semax semax met-glu-his-phe-pro-gly-pro n-acetyl semax (related) mehfpgp h-mehfpgp-oh acth(4-7)-pgp (pro8,gly9,pro10)acth-(4-10) acth(4-10) analog (heptapeptide shorthand) semax 0.1% semax 1% semax-hept (1% product talk) semax\u00ae (russian pharmacy brand discussions) \u0441\u0435\u043c\u0430\u043a\u0441 n-acetyl semax (related analog \u2014 not identical) n-acetyl semax amidate / nasa (related analog \u2014 not identical) cas 80714-61-0 (primary registry discussions) mw ~813.93 g/mol (c37h51n9o10s) semax met-glu-his-phe-pro-gly-pro mehfpgp h-mehfpgp-oh acth(4-7)-pgp (pro8,gly9,pro10)acth-(4-10) focus brain fog exam attention nasal word finding anxiety insomnia hair loss hair shedding cognition focus neuroprotection discussion mood attention working memory (discussed) memory / learning support (discussed) mental performance under load or fatigue stroke / cerebrovascular recovery discussion (russian clinical history) transient ischemic attack discussion (product history) optic-nerve / visual-pathway discussion (russian clinical history) mood / stress resilience (mild; secondary to focus for many) adhd-adjacent focus talk (community only; not an approved indication) exam / deep-work / high-cognitive-load sprints nootropic stacking (classically with selank) peptic-ulcer adjunct discussion (russian product history \u2014 not western nootropic use) alcohol-delirium / post-toxic cognitive recovery discussion (russian clinical series) focus brain fog exam attention nasal word finding anxiety insomnia hair loss hair shedding semax is a synthetic seven-amino-acid peptide derived from an acth fragment, discussed for focus and cognitive function. one user described clearer perception and a calmer sense of well-being, with another drug also in use. semax is a peptide for focus. sharper task focus, less mental drift; often described as \u201ccleaner\u201d than heavy caffeine or adderall-class stims \u2014 more \u201con-task\u201d than forced drive. cleaner-than-caffeine talk. nose burn is the everyday complaint. cognitive / nootropic peptides peptide systemic brain-first \u2014 intranasal is the main clinical and community route. subcutaneous use is a separate minority practice; oral use is not mainstream. systemic whole-body circulating", "legal_class": null }, { "id": 20, "slug": "selank", "name": "Selank", "aliases": [ "TP-7", "Thr-Lys-Pro-Arg-Pro-Gly-Pro", "TKPRPGP", "Selanc", "\u0421\u0435\u043b\u0430\u043d\u043a", "Selank 0.15% (Russian nasal drops product form)", "tuftsin-derived heptapeptide (research framing)", "threonyl-lysyl-prolyl-arginyl-prolyl-glycyl-proline" ], "type": "Peptide", "category": "Cognitive / nootropic peptides", "goals_use_cases": [ "anxiety discussion", "mood", "cognition", "stress", "anxiety discussion (GAD / generalized anxiety talk)", "mood steadiness", "cognition under stress", "stress / neurasthenia-style fatigue talk", "focus under pressure without stimulant edge", "anxiolytic without benzo-style sedation (discussed)", "social / performance / exam anxiety talk", "immune-modulatory narrative (secondary; tuftsin lineage)", "nootropic stacking (esp. with Semax)", "\u201ccalm focus\u201d stack role vs pure stimulation" ], "delivery_methods": [ "nasal", "subcutaneous" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "selank", "TP-7", "Thr-Lys-Pro-Arg-Pro-Gly-Pro", "TKPRPGP", "Selanc", "\u0421\u0435\u043b\u0430\u043d\u043a", "anxiety", "calm", "stress", "rumination", "brain fog", "flat", "social anxiety", "word finding" ], "feel_search": [ "anxiety", "calm", "stress", "rumination", "brain fog", "flat", "social anxiety", "word finding" ], "summary": "Selank is a synthetic seven-amino-acid analogue of the immune peptide Tuftsin, discussed for anxiety and calm focus.", "search_blob": "selank selank tp-7 thr-lys-pro-arg-pro-gly-pro tkprpgp selanc \u0441\u0435\u043b\u0430\u043d\u043a selank 0.15% (russian nasal drops product form) tuftsin-derived heptapeptide (research framing) threonyl-lysyl-prolyl-arginyl-prolyl-glycyl-proline selank tp-7 thr-lys-pro-arg-pro-gly-pro tkprpgp selanc \u0441\u0435\u043b\u0430\u043d\u043a anxiety calm stress rumination brain fog flat social anxiety word finding anxiety discussion mood cognition stress anxiety discussion (gad / generalized anxiety talk) mood steadiness cognition under stress stress / neurasthenia-style fatigue talk focus under pressure without stimulant edge anxiolytic without benzo-style sedation (discussed) social / performance / exam anxiety talk immune-modulatory narrative (secondary; tuftsin lineage) nootropic stacking (esp. with semax) \u201ccalm focus\u201d stack role vs pure stimulation anxiety calm stress rumination brain fog flat social anxiety word finding selank is a synthetic seven-amino-acid analogue of the immune peptide tuftsin, discussed for anxiety and calm focus. one nasal user described calm, focus and well-being; they stopped repurchasing because of route and product-quality concerns. selank is a nasal peptide people look up for calm. clearer thinking once \u201cnoise\u201d falls \u2014 mixed attribution (true nootropic vs secondary to anxiolysis). often paired with semax. nose irritation is still the #1 complaint. cognitive / nootropic peptides peptide systemic systemic cns framing \u2014 canonical route is intranasal for brain/anxiety endpoints, not local tissue repair. systemic whole-body circulating", "legal_class": null }, { "id": 21, "slug": "thymosin-alpha-1", "name": "Thymosin Alpha-1", "aliases": [ "T\u03b11", "Zadaxin", "Thymalfasin", "Ta1", "TA1", "Thymosin \u03b11", "Thymosin alpha 1", "Thymosin-\u03b11", "T alpha 1", "thymosin a1" ], "type": "Peptide", "category": "Immune peptides", "goals_use_cases": [ "immune", "recovery", "longevity discussion", "immune modulation", "antiviral interest (historical / adjunct)", "oncology adjunct (discussed)", "vaccine response interest", "chronic infection support narratives", "inflammation balance (discussed)", "performance continuity (illness recovery)", "immunosenescence / aging immune talk", "critical illness / sepsis adjunct (trial context)", "long-COVID / post-viral forums (anecdotal)" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "thymosin-alpha-1", "thymosin alpha 1", "thymosinalpha1", "Thymosin Alpha-1", "T\u03b11", "Ta1", "immune", "sick", "cold", "recovery", "CD4", "WBC", "compounding", "10mg vial" ], "feel_search": [ "immune", "sick", "cold", "recovery", "CD4", "WBC", "compounding" ], "summary": "Thymosin alpha-1, or thymalfasin, is a synthetic 28-amino-acid thymic peptide used in immune-related clinical research and treatment.", "search_blob": "thymosin alpha-1 thymosin-alpha-1 t\u03b11 zadaxin thymalfasin ta1 ta1 thymosin \u03b11 thymosin alpha 1 thymosin-\u03b11 t alpha 1 thymosin a1 thymosin-alpha-1 thymosin alpha 1 thymosinalpha1 thymosin alpha-1 t\u03b11 ta1 immune sick cold recovery cd4 wbc compounding 10mg vial immune recovery longevity discussion immune modulation antiviral interest (historical / adjunct) oncology adjunct (discussed) vaccine response interest chronic infection support narratives inflammation balance (discussed) performance continuity (illness recovery) immunosenescence / aging immune talk critical illness / sepsis adjunct (trial context) long-covid / post-viral forums (anecdotal) immune sick cold recovery cd4 wbc compounding thymosin alpha-1, or thymalfasin, is a synthetic 28-amino-acid thymic peptide used in immune-related clinical research and treatment. reports range from clearer sinuses or allergy relief to dizziness, joint discomfort and heartburn; the cause of one adverse reaction remained uncertain. thymosin alpha-1 is a peptide people look up for immune support. other commenters reported no such effects, brief pain/numbness, clear sinuses or months-long allergy relief. usually twice a week, not a daily gh-style pin. 1.6 mg is milligrams \u2014 not a bpc mcg chart. ruo 10 mg vials are not one shot. immune peptides peptide systemic systemic \u2014 circulating immune-modulating thymic peptide (t-cell / innate\u2013adaptive host defense), not a local soft-tissue repair agent like tb-500 or bpc-157. systemic whole-body circulating", "legal_class": null }, { "id": 22, "slug": "ll-37", "name": "LL-37", "aliases": [ "Cathelicidin LL-37", "CAP-18 fragment", "Cathelicidin antimicrobial peptide", "hCAP-18 fragment", "CAP-18 C-terminal peptide", "hCAP18-derived peptide", "Ropocamptide (investigational topical designation / Promore Pharma)", "LL37", "LL 37", "Human cathelicidin", "FALL-39 (historical related designation talk)" ], "type": "Peptide", "category": "Immune peptides", "goals_use_cases": [ "immune", "antimicrobial discussion", "skin", "gut health (discussed)", "wound healing (topical trial context)", "anti-biofilm (preclinical)", "chronic infection discussion", "Lyme / mold / CIRS-adjacent forum talk", "sinus / stubborn infection narratives", "inflammation modulation (double-edged)", "post-viral immune-support talk", "host-defense peptide research" ], "delivery_methods": [ "subcutaneous", "topical" ], "discussion_popularity": "High", "reach": "Mixed", "misspellings_search_terms": [ "ll-37", "ll 37", "ll37", "Cathelicidin LL-37", "Cathelicidin antimicrobial peptide", "hCAP-18 fragment", "lyme", "mold", "immune", "itch", "skin", "sibo", "gut", "topical" ], "feel_search": [ "lyme", "mold", "immune", "itch", "skin", "sibo", "gut", "topical" ], "summary": "LL-37 is a human antimicrobial peptide involved in immune signaling, studied experimentally and discussed for difficult infections and wound healing.", "search_blob": "ll-37 ll-37 cathelicidin ll-37 cap-18 fragment cathelicidin antimicrobial peptide hcap-18 fragment cap-18 c-terminal peptide hcap18-derived peptide ropocamptide (investigational topical designation / promore pharma) ll37 ll 37 human cathelicidin fall-39 (historical related designation talk) ll-37 ll 37 ll37 cathelicidin ll-37 cathelicidin antimicrobial peptide hcap-18 fragment lyme mold immune itch skin sibo gut topical immune antimicrobial discussion skin gut health (discussed) wound healing (topical trial context) anti-biofilm (preclinical) chronic infection discussion lyme / mold / cirs-adjacent forum talk sinus / stubborn infection narratives inflammation modulation (double-edged) post-viral immune-support talk host-defense peptide research lyme mold immune itch skin sibo gut topical ll-37 is a human antimicrobial peptide involved in immune signaling, studied experimentally and discussed for difficult infections and wound healing. reports range from little change to local reactions, flu-like symptoms or perceived benefit without cure. co-treatments are common, and a 'herx' feeling does not prove infection is being cleared. ll-37 is a peptide people look up for immune support. reports remain mixed: one user lowered an unspecified amount after early symptoms, and another described benefit without cure. the pin can itch or wheal. careful posters run short blocks, not forever. immune peptides peptide mixed mixed \u2014 human trials used topical ulcer gel; community infection and immune use is usually subq, and those routes are not interchangeable. mixed local systemic", "legal_class": null }, { "id": 23, "slug": "kpv", "name": "KPV", "aliases": [ "Lys-Pro-Val", "alpha-MSH fragment KPV", "Lysine-Proline-Valine", "\u03b1-MSH(11-13)", "\u03b1-MSH 11-13", "MSH 11-13", "KPV tripeptide", "alpha-MSH C-terminal tripeptide", "Ac-KPV (acetylated forms discussed)" ], "type": "Peptide", "category": "Gut & inflammation peptides", "goals_use_cases": [ "gut health", "inflammation discussion", "skin", "inflammation (discussed)", "GI lining / barrier support (discussed)", "IBD-model research interest (colitis threads)", "skin / dermatitis / barrier irritation", "immune signaling / cytokine calm (discussed)", "histamine / MCAS-adjacent discussion (anecdotal)", "antimicrobial / \u201cbug load\u201d talk (lab angle)", "recovery continuity (as stack partner)", "oral peptide option when injectables are avoided" ], "delivery_methods": [ "oral", "subcutaneous", "topical" ], "discussion_popularity": "High", "reach": "Mixed", "misspellings_search_terms": [ "kpv", "Lys-Pro-Val", "Lysine-Proline-Valine", "alpha-MSH fragment KPV", "\u03b1-MSH(11-13)", "\u03b1-MSH 11-13", "gut", "inflammation", "colitis", "klow", "pcac", "503a", "compounding", "fda approved", "kpv nasal", "calprotectin", "herx", "flare", "nasal" ], "feel_search": [ "gut", "inflammation", "colitis", "klow", "herx", "flare", "nasal" ], "summary": "KPV is a three-amino-acid fragment of alpha-MSH, an experimental peptide discussed for gut discomfort and inflammatory skin symptoms.", "search_blob": "kpv kpv lys-pro-val alpha-msh fragment kpv lysine-proline-valine \u03b1-msh(11-13) \u03b1-msh 11-13 msh 11-13 kpv tripeptide alpha-msh c-terminal tripeptide ac-kpv (acetylated forms discussed) kpv lys-pro-val lysine-proline-valine alpha-msh fragment kpv \u03b1-msh(11-13) \u03b1-msh 11-13 gut inflammation colitis klow pcac 503a compounding fda approved kpv nasal calprotectin herx flare nasal gut health inflammation discussion skin inflammation (discussed) gi lining / barrier support (discussed) ibd-model research interest (colitis threads) skin / dermatitis / barrier irritation immune signaling / cytokine calm (discussed) histamine / mcas-adjacent discussion (anecdotal) antimicrobial / \u201cbug load\u201d talk (lab angle) recovery continuity (as stack partner) oral peptide option when injectables are avoided gut inflammation colitis klow herx flare nasal kpv is a three-amino-acid fragment of alpha-msh, an experimental peptide discussed for gut discomfort and inflammatory skin symptoms. gut reports conflict: some describe less gas or irritation, while others report bloating, diarrhea, dizziness or no benefit. feeling worse does not demonstrate a beneficial 'die-off' reaction. kpv is a peptide people look up for gut. people report calmer gi days, less post-meal irritation, fewer \u201cflare-like\u201d windows over multi-week runs. oral is the gut-first story; subq is the systemic story. don\u2019t treat those mcg as the same. july 2026 compounding-vote headlines are not \u201cfda approved ibd drug.\u201d gut & inflammation peptides peptide mixed mixed \u2014 oral for gut-first, subq for whole-body calm, topical for skin. pick a job. mixed local systemic", "legal_class": null }, { "id": 24, "slug": "mots-c", "name": "MOTS-c", "aliases": [ "Mitochondrial ORF of the Twelve S c", "MOTS c", "Mitochondrial open reading frame of the 12S rRNA-c", "MOTSc", "MOTS-C", "mitochondrial-derived peptide MOTS-c", "MRWQEMGYIFYPRKLR", "MT-RNR1-encoded peptide" ], "type": "Peptide", "category": "Mitochondrial & metabolic peptides", "goals_use_cases": [ "metabolic health", "performance", "longevity", "fat loss discussion", "insulin sensitivity (discussed)", "performance / exercise capacity", "exercise mimetic narratives", "longevity / healthspan", "mitochondrial function", "energy / fatigue discussion", "body recomposition (discussed)", "age-related metabolic decline", "glucose handling / metabolic flexibility", "NAFLD / fatty liver discussion (via CB4211 analog trial)", "bone metabolism interest (preclinical)" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "mots-c", "mots c", "motsc", "Mitochondrial ORF of the Twelve S c", "Mitochondrial open reading frame of the 12S rRNA-c", "mitochondrial-derived peptide MOTS-c", "energy", "endurance", "mito", "fat loss", "ATX-304", "ATX", "compounding", "AMPK", "WADA" ], "feel_search": [ "energy", "endurance", "mito", "fat loss", "ATX-304", "AMPK", "WADA" ], "summary": "MOTS-c is a 16-amino-acid mitochondrial peptide studied in metabolism and discussed as an experimental injectable for endurance or recovery.", "search_blob": "mots-c mots-c mitochondrial orf of the twelve s c mots c mitochondrial open reading frame of the 12s rrna-c motsc mots-c mitochondrial-derived peptide mots-c mrwqemgyifyprklr mt-rnr1-encoded peptide mots-c mots c motsc mitochondrial orf of the twelve s c mitochondrial open reading frame of the 12s rrna-c mitochondrial-derived peptide mots-c energy endurance mito fat loss atx-304 atx compounding ampk wada metabolic health performance longevity fat loss discussion insulin sensitivity (discussed) performance / exercise capacity exercise mimetic narratives longevity / healthspan mitochondrial function energy / fatigue discussion body recomposition (discussed) age-related metabolic decline glucose handling / metabolic flexibility nafld / fatty liver discussion (via cb4211 analog trial) bone metabolism interest (preclinical) energy endurance mito fat loss atx-304 ampk wada mots-c is a 16-amino-acid mitochondrial peptide studied in metabolism and discussed as an experimental injectable for endurance or recovery. some report better workouts or endurance; others describe no effect, fatigue, nausea or headaches. injection soreness can be prominent, and benefits may not persist after stopping. mots-c is a peptide people look up for fat loss and energy. users often describe steadier training energy and recovery over weeks rather than a stimulant \u201ckick.\u201d. people argue weekly boluses vs tiny daily pins. 2026 x also compares it to oral atx-304. don\u2019t copy the analog\u2019s 25 mg/day trial onto this. mitochondrial & metabolic peptides peptide systemic whole-body metabolic talk, with muscle as the organ people name. systemic whole-body circulating", "legal_class": null }, { "id": 25, "slug": "ss-31", "name": "SS-31", "aliases": [ "Elamipretide", "Bendavia", "MTP-131", "Elamipretide HCl", "MTP131", "Forzinity (FDA brand for Barth syndrome)", "Szeto-Schiller peptide 31", "Szeto-Schiller 31", "D-Arg-Dmt-Lys-Phe-NH2" ], "type": "Peptide", "category": "Mitochondrial & metabolic peptides", "goals_use_cases": [ "longevity", "performance", "mitochondrial discussion", "recovery", "longevity / healthy aging mitochondrial support", "performance and work capacity (discussed)", "mitochondrial disease discussion (Barth, PMM)", "recovery and exercise tolerance", "energy / fatigue reduction (discussed)", "cardiovascular research interest (HFrEF, ischemia)", "muscle function in mito-disease context", "cellular energy / ATP and ROS narratives", "anti-aging cardiolipin / ETC membrane support", "retinal / dry AMD pipeline interest (distinct indication)", "ME/CFS and chronic fatigue experiment talk (anecdotal)", "kidney / ischemia-reperfusion research interest (preclinical)" ], "delivery_methods": [ "subcutaneous", "IV" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "ss-31", "ss 31", "ss31", "Elamipretide", "Elamipretide HCl", "Bendavia", "energy", "fatigue", "mito", "crash", "elamipretide", "5-10 mg", "40 mg", "Forzinity", "high dose" ], "feel_search": [ "energy", "fatigue", "mito", "crash", "elamipretide", "5-10 mg", "40 mg", "Forzinity", "high dose" ], "summary": "SS-31, or elamipretide, is a synthetic four-amino-acid peptide associated with mitochondrial research and energy-related interests.", "search_blob": "ss-31 ss-31 elamipretide bendavia mtp-131 elamipretide hcl mtp131 forzinity (fda brand for barth syndrome) szeto-schiller peptide 31 szeto-schiller 31 d-arg-dmt-lys-phe-nh2 ss-31 ss 31 ss31 elamipretide elamipretide hcl bendavia energy fatigue mito crash elamipretide 5-10 mg 40 mg forzinity high dose longevity performance mitochondrial discussion recovery longevity / healthy aging mitochondrial support performance and work capacity (discussed) mitochondrial disease discussion (barth, pmm) recovery and exercise tolerance energy / fatigue reduction (discussed) cardiovascular research interest (hfref, ischemia) muscle function in mito-disease context cellular energy / atp and ros narratives anti-aging cardiolipin / etc membrane support retinal / dry amd pipeline interest (distinct indication) me/cfs and chronic fatigue experiment talk (anecdotal) kidney / ischemia-reperfusion research interest (preclinical) energy fatigue mito crash elamipretide 5-10 mg 40 mg forzinity high dose ss-31, or elamipretide, is a synthetic four-amino-acid peptide associated with mitochondrial research and energy-related interests. one person with me/cfs described heavier fatigue, nightmares and gi symptoms, later possible energy improvement and another crash. ss-31 is a peptide people look up for longevity. a minority claim next-day recovery or morning energy early \u2014 anecdote only. not a stimulant kick. site redness is the everyday complaint. 2026 also argues 1\u20132 mg vs a 10 mg+ \u201cstop baby-dosing\u201d camp. mitochondrial & metabolic peptides peptide systemic systemic \u2014 mitochondria-targeting tetrapeptide studied by subq and iv routes; forzinity is a narrow barth-syndrome prescription path. systemic whole-body circulating", "legal_class": null }, { "id": 26, "slug": "5-amino-1mq", "name": "5-Amino-1MQ", "aliases": [ "5-amino-1-methylquinolinium", "5A1MQ", "5-amino-1-methylquinolinium iodide", "5-amino-1-methylquinolinium monochloride", "5A-1MQ", "5A-M1Q", "5A-1MQ (monochloride salt)", "5-AMQ", "5-AMQ (PK literature)", "5-Amino-1-MQ", "5 amino 1MQ", "NNMT inhibitor 5-amino-1MQ", "NNMTi 5-amino-1MQ", "NNMTi 5A-1MQ" ], "type": "Non-peptide", "category": "Metabolic research compounds", "goals_use_cases": [ "fat loss", "metabolic health", "NNMT discussion", "body recomposition", "NNMT / NAD+ pathway discussion", "visceral / stubborn fat narratives", "GLP-1 stack adjunct (community)", "insulin sensitivity research (preclinical)", "energy expenditure without appetite cut (animal framing)", "muscle function / aged-muscle talk (preclinical)", "fatty-liver / steatosis interest (preclinical 28-day work)", "longevity / metabolic aging talk (emerging)", "diet-switch synergy (animal framing)", "MitoPrime / multi-agent mito blend talk" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "5-amino-1mq", "5 amino 1mq", "5amino1mq", "5-amino-1-methylquinolinium", "5-amino-1-methylquinolinium iodide", "5-amino-1-methylquinolinium monochloride", "stubborn fat", "recomp", "nnmt", "waist", "flush", "flushing", "50mg", "150mg" ], "feel_search": [ "stubborn fat", "recomp", "nnmt", "waist", "flush", "flushing", "50mg", "150mg" ], "summary": "5-Amino-1MQ is a small-molecule NNMT inhibitor studied for metabolism and discussed for fat loss; it is not a peptide.", "search_blob": "5-amino-1mq 5-amino-1mq 5-amino-1-methylquinolinium 5a1mq 5-amino-1-methylquinolinium iodide 5-amino-1-methylquinolinium monochloride 5a-1mq 5a-m1q 5a-1mq (monochloride salt) 5-amq 5-amq (pk literature) 5-amino-1-mq 5 amino 1mq nnmt inhibitor 5-amino-1mq nnmti 5-amino-1mq nnmti 5a-1mq 5-amino-1mq 5 amino 1mq 5amino1mq 5-amino-1-methylquinolinium 5-amino-1-methylquinolinium iodide 5-amino-1-methylquinolinium monochloride stubborn fat recomp nnmt waist flush flushing 50mg 150mg fat loss metabolic health nnmt discussion body recomposition nnmt / nad+ pathway discussion visceral / stubborn fat narratives glp-1 stack adjunct (community) insulin sensitivity research (preclinical) energy expenditure without appetite cut (animal framing) muscle function / aged-muscle talk (preclinical) fatty-liver / steatosis interest (preclinical 28-day work) longevity / metabolic aging talk (emerging) diet-switch synergy (animal framing) mitoprime / multi-agent mito blend talk stubborn fat recomp nnmt waist flush flushing 50mg 150mg 5-amino-1mq is a small-molecule nnmt inhibitor studied for metabolism and discussed for fat loss; it is not a peptide. a month-long oral log reports no stimulant rush, subtle waist changes after two to three weeks and muted emotions later. diet and training complicate attribution. 5-amino-1mq is an oral compound for fat loss. fat-cell-size / recomp narrative without the appetite crash of semaglutide-class drugs; heavily stacked late into glp-1 plateaus. dose charts are chaotic \u2014 50\u2013150 mg oral vs mcg inject are different worlds. warmth/flush is not a niacin flush. metabolic research compounds non-peptide systemic systemic \u2014 nnmt / nad+ and fat-metabolism discussion; adipose, muscle and liver exposure comes from animal work, not spot-fat targeting. systemic whole-body circulating", "legal_class": null }, { "id": 27, "slug": "slu-pp-332", "name": "SLU-PP-332", "aliases": [ "SLU PP 332", "ERR agonist discussion compound", "SLUPP332", "SLU-PP332", "SLU-PP 332", "ERR pan-agonist (SLU-PP-332)", "ERR agonist exercise-mimetic discussion compound", "Saint Louis University PP-332", "CAS 303760-60-3" ], "type": "Non-peptide", "category": "Metabolic research compounds", "goals_use_cases": [ "fat loss", "endurance discussion", "metabolic health", "exercise-mimetic research", "energy expenditure (discussed)", "mitochondrial / oxidative capacity (discussed)", "body recomposition (discussed)", "performance continuity (discussed)", "fatty-acid oxidation shift (discussed)", "glucose / insulin markers in mice (discussed)", "cardio stamina without more training (discussed)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "slu-pp-332", "slu pp 332", "slupp332", "SLU-PP332", "SLU-PP 332", "ERR pan-agonist (SLU-PP-332)", "endurance", "cardio", "exercise mimetic", "sweat", "915", "enteric", "oral bioavailability", "DMSO" ], "feel_search": [ "endurance", "cardio", "exercise mimetic", "sweat", "915", "enteric", "oral bioavailability", "DMSO" ], "summary": "SLU-PP-332 is an experimental small molecule that activates estrogen-related receptors, studied for metabolic and exercise-like effects.", "search_blob": "slu-pp-332 slu-pp-332 slu pp 332 err agonist discussion compound slupp332 slu-pp332 slu-pp 332 err pan-agonist (slu-pp-332) err agonist exercise-mimetic discussion compound saint louis university pp-332 cas 303760-60-3 slu-pp-332 slu pp 332 slupp332 slu-pp332 slu-pp 332 err pan-agonist (slu-pp-332) endurance cardio exercise mimetic sweat 915 enteric oral bioavailability dmso fat loss endurance discussion metabolic health exercise-mimetic research energy expenditure (discussed) mitochondrial / oxidative capacity (discussed) body recomposition (discussed) performance continuity (discussed) fatty-acid oxidation shift (discussed) glucose / insulin markers in mice (discussed) cardio stamina without more training (discussed) endurance cardio exercise mimetic sweat 915 enteric oral bioavailability dmso slu-pp-332 is an experimental small molecule that activates estrogen-related receptors, studied for metabolic and exercise-like effects. one user described no initial effect, then more energy with evening exhaustion and difficult sleep at a higher amount. slu-pp-332 is an oral compound people look up for fat loss. commonly null or subtle unless stacked or dosed higher; oral micro-capsules especially often \u201cnothing.\u201d tiny 250 mcg capsules get called placebo-tier. 2026 talk often says buy 915 if you want oral. metabolic research compounds non-peptide systemic systemic pan-err research aimed at fuel use and muscle oxidative programs; published efficacy is in mice, not local injection-site repair. systemic whole-body circulating", "legal_class": null }, { "id": 28, "slug": "nad-plus", "name": "NAD+", "aliases": [ "Nicotinamide adenine dinucleotide", "NAD plus", "NAD infusions", "NAD", "NAD IV", "NAD drip", "NAD+ therapy", "\u03b2-NAD", "beta-NAD", "Coenzyme 1 (historical label)", "NAD+ injection", "NAD SubQ", "Niagen IV (NR IV comparator brand talk)", "BR+NAD / Brain Restoration Plus NAD (addiction-clinic brand protocol)" ], "type": "Non-peptide", "category": "Longevity & cellular energy", "goals_use_cases": [ "longevity", "energy", "cognition", "recovery", "longevity / anti-aging narrative", "cellular energy / mitochondrial support", "cognition / brain fog / mental clarity", "recovery / burnout reset", "performance continuity / training deload adjacency", "jet lag / travel recovery (discussed)", "addiction-clinic historical / detox / craving support interest", "mood / motivation (anecdotal)", "metabolic / redox talk", "DNA-repair / sirtuin / PARP cofactor framing", "wellness-clinic IV lounge culture", "post-viral / chronic-fatigue clinic menus (marketing, sparse hard trials)", "comparison path vs daily oral NMN or NR" ], "delivery_methods": [ "IV", "subcutaneous", "nasal", "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "nad-plus", "nad plus", "nadplus", "NAD+", "Nicotinamide adenine dinucleotide", "NAD", "brain fog", "energy", "nad drip", "flush", "chest pressure", "crash", "wired", "nausea", "nasal spray", "endotoxin" ], "feel_search": [ "brain fog", "energy", "nad drip", "flush", "chest pressure", "crash", "wired", "nausea", "nasal spray", "endotoxin" ], "summary": "NAD+ is a cellular coenzyme sold as IV drips and injectables for energy or longevity; it differs from oral precursors such as NR and NMN.", "search_blob": "nad+ nad-plus nicotinamide adenine dinucleotide nad plus nad infusions nad nad iv nad drip nad+ therapy \u03b2-nad beta-nad coenzyme 1 (historical label) nad+ injection nad subq niagen iv (nr iv comparator brand talk) br+nad / brain restoration plus nad (addiction-clinic brand protocol) nad-plus nad plus nadplus nad+ nicotinamide adenine dinucleotide nad brain fog energy nad drip flush chest pressure crash wired nausea nasal spray endotoxin longevity energy cognition recovery longevity / anti-aging narrative cellular energy / mitochondrial support cognition / brain fog / mental clarity recovery / burnout reset performance continuity / training deload adjacency jet lag / travel recovery (discussed) addiction-clinic historical / detox / craving support interest mood / motivation (anecdotal) metabolic / redox talk dna-repair / sirtuin / parp cofactor framing wellness-clinic iv lounge culture post-viral / chronic-fatigue clinic menus (marketing, sparse hard trials) comparison path vs daily oral nmn or nr brain fog energy nad drip flush chest pressure crash wired nausea nasal spray endotoxin nad+ is a cellular coenzyme sold as iv drips and injectables for energy or longevity; it differs from oral precursors such as nr and nmn. infusions can feel uncomfortable, with nausea, pressure or anxiety affected by drip speed. later reports range from short-lived clarity to no worthwhile change after several sessions. nad+ is a compound for energy. common \u201crecharged,\u201d wired-clear, or less-drained claim after a single drip; confounded by saline volume, b-vitamins, rest day, caffeine, and placebo. fast drips feel awful (chest pressure, flush). oral nad+ is not treated as the same as iv. 2026 fight is nasal vs iv vs subq \u2014 sprays are not treated as the same as a drip. longevity & cellular energy non-peptide systemic systemic cofactor (redox, sirtuins, parps, mitochondria). systemic whole-body circulating", "legal_class": null }, { "id": 29, "slug": "nmn", "name": "NMN", "aliases": [ "Nicotinamide mononucleotide", "\u03b2-NMN", "beta-NMN", "\u03b2-Nicotinamide mononucleotide", "beta-Nicotinamide mononucleotide", "Nicotinamide mononucleotide (\u03b2 form)", "MIB-626 (pharma-grade / microcrystalline \u03b2-NMN in trials)", "NMN powder / NMN capsules (consumer forms)", "\u03b2-Nicotinamide mononucleotide monohydrate (label chemistry talk)" ], "type": "Non-peptide", "category": "Longevity & cellular energy", "goals_use_cases": [ "longevity", "energy", "metabolic health", "longevity / healthy aging", "cellular NAD+ support", "energy / daytime vitality (subjective)", "metabolic health / insulin sensitivity (discussed)", "physical performance / aerobic capacity (discussed)", "walking endurance / 6-minute walk narratives", "muscle function / older-adult gait and grip (discussed)", "sleep quality / drowsiness (afternoon-dosing trial talk)", "recovery continuity alongside training", "anti-aging media / Sinclair-adjacent hype", "cognitive energy narratives (minority / confounded)", "comparison alternative to NR, niacin, NAD+ IV", "gut NAD / microbiome Preiss\u2013Handler pathway interest (emerging trial talk)" ], "delivery_methods": [ "oral", "sublingual (marketed)" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "nmn", "Nicotinamide mononucleotide", "\u03b2-NMN", "beta-NMN", "\u03b2-Nicotinamide mononucleotide", "beta-Nicotinamide mononucleotide", "energy", "longevity", "brain fog", "nad", "homocysteine", "TMG", "FDA", "sublingual", "insomnia" ], "feel_search": [ "energy", "longevity", "brain fog", "nad", "homocysteine", "sublingual", "insomnia" ], "summary": "NMN is nicotinamide mononucleotide, an oral NAD+ precursor marketed for energy and healthy aging; higher blood NAD+ is not a felt benefit.", "search_blob": "nmn nmn nicotinamide mononucleotide \u03b2-nmn beta-nmn \u03b2-nicotinamide mononucleotide beta-nicotinamide mononucleotide nicotinamide mononucleotide (\u03b2 form) mib-626 (pharma-grade / microcrystalline \u03b2-nmn in trials) nmn powder / nmn capsules (consumer forms) \u03b2-nicotinamide mononucleotide monohydrate (label chemistry talk) nmn nicotinamide mononucleotide \u03b2-nmn beta-nmn \u03b2-nicotinamide mononucleotide beta-nicotinamide mononucleotide energy longevity brain fog nad homocysteine tmg fda sublingual insomnia longevity energy metabolic health longevity / healthy aging cellular nad+ support energy / daytime vitality (subjective) metabolic health / insulin sensitivity (discussed) physical performance / aerobic capacity (discussed) walking endurance / 6-minute walk narratives muscle function / older-adult gait and grip (discussed) sleep quality / drowsiness (afternoon-dosing trial talk) recovery continuity alongside training anti-aging media / sinclair-adjacent hype cognitive energy narratives (minority / confounded) comparison alternative to nr, niacin, nad+ iv gut nad / microbiome preiss\u2013handler pathway interest (emerging trial talk) energy longevity brain fog nad homocysteine sublingual insomnia nmn is nicotinamide mononucleotide, an oral nad+ precursor marketed for energy and healthy aging; higher blood nad+ is not a felt benefit. some describe subtle energy or stamina, while others feel little. gi upset, a wired feeling or earlier waking can occur; positive blood markers do not guarantee feeling better. nmn is an oral compound for longevity. common reassess window \u2014 clearer recovery/energy narrative vs \u201chype without signal\u201d; also when many decide cost is not worth it. most people feel nothing dramatic the first week. 250 mg is the patient start; ~500 mg is the 2026 bottle people finish; 1 g is the influencer copy. longevity & cellular energy non-peptide systemic systemic oral nad+ precursor; blood nad+ rises do not prove equal exposure or benefit in every tissue. systemic whole-body circulating", "legal_class": null }, { "id": 30, "slug": "rapamycin", "name": "Rapamycin", "aliases": [ "Sirolimus", "Rapamune", "Rapamune (brand)", "Rapamune / sirolimus generics", "AY-22989 (historical research designation)", "mTOR inhibitor (class discussion)", "Rapalog parent compound", "Rapa (forum shorthand)", "Sirolimus oral tablet / solution", "Compounded rapamycin (clinic/telehealth form)" ], "type": "Non-peptide", "category": "Longevity & mTOR", "goals_use_cases": [ "longevity", "immune modulation discussion", "anti-aging discussion", "longevity / healthspan", "immune modulation / immunosenescence discussion", "mTOR / cellular aging research", "autophagy / CR-mimetic framing", "healthspan biomarkers (DEXA, lipids, self-report)", "cancer-prevention narratives (research interest; not proven longevity indication)", "metabolic aging interest", "ovarian aging / reproductive aging interest (VIBRANT and related)", "sarcopenia / lean-mass talk (PEARL secondary signals in women)", "periodontal / oral-aging research interest", "companion-animal aging bridge (Dog Aging Project TRIAD)", "ME/CFS / fatigue exploratory talk (community, sparse)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "rapamycin", "Sirolimus", "Rapamune", "Rapamune (brand)", "Rapamune / sirolimus generics", "AY-22989 (historical research designation)", "longevity", "mouth sores", "ulcers", "weekly", "mtor", "grapefruit", "sirolimus", "lipids", "infection", "bloodwork" ], "feel_search": [ "longevity", "mouth sores", "ulcers", "weekly", "mtor", "grapefruit", "sirolimus", "lipids", "infection", "bloodwork" ], "summary": "Rapamycin is sirolimus, a prescription mTOR-inhibiting drug also discussed in longevity experiments.", "search_blob": "rapamycin rapamycin sirolimus rapamune rapamune (brand) rapamune / sirolimus generics ay-22989 (historical research designation) mtor inhibitor (class discussion) rapalog parent compound rapa (forum shorthand) sirolimus oral tablet / solution compounded rapamycin (clinic/telehealth form) rapamycin sirolimus rapamune rapamune (brand) rapamune / sirolimus generics ay-22989 (historical research designation) longevity mouth sores ulcers weekly mtor grapefruit sirolimus lipids infection bloodwork longevity immune modulation discussion anti-aging discussion longevity / healthspan immune modulation / immunosenescence discussion mtor / cellular aging research autophagy / cr-mimetic framing healthspan biomarkers (dexa, lipids, self-report) cancer-prevention narratives (research interest; not proven longevity indication) metabolic aging interest ovarian aging / reproductive aging interest (vibrant and related) sarcopenia / lean-mass talk (pearl secondary signals in women) periodontal / oral-aging research interest companion-animal aging bridge (dog aging project triad) me/cfs / fatigue exploratory talk (community, sparse) longevity mouth sores ulcers weekly mtor grapefruit sirolimus lipids infection bloodwork rapamycin is sirolimus, a prescription mtor-inhibiting drug also discussed in longevity experiments. forum users describe more energy, less aching, or a tired-but-euphoric feeling; several explicitly question how much is placebo. rapamycin is a drug for longevity. mid- or late-life rapamycin extends median and max lifespan; commonly cited ~10\u201325% median range depending on sex, strain, dose, and start age. longevity & mtor non-peptide systemic systemic \u2014 whole-body mtorc1 modulation via oral absorption; not a local/injury or peptide-style site-injection agent. systemic whole-body circulating", "legal_class": null }, { "id": 31, "slug": "ghrp-2", "name": "GHRP-2", "aliases": [ "Pralmorelin", "KP-102", "Pralmorelin hydrochloride", "KP-102LN", "GPA 748", "GPA-748", "WAY-GPA-748", "GHRP Kaken 100", "Growth hormone-releasing peptide-2", "GHRP2", "GHRP 2", "D-Ala-D-2Nal-Ala-Trp-D-Phe-Lys-NH2" ], "type": "Peptide", "category": "Growth hormone axis", "goals_use_cases": [ "muscle growth", "appetite", "recovery", "fat loss discussion", "appetite / hard-gainer bulk", "body composition", "performance", "sleep (discussed)", "anti-aging discussion", "IGF-1 elevation (discussed)", "GH deficiency diagnostic (Japan, clinical)", "lean recomp with controllable hunger vs GHRP-6" ], "delivery_methods": [ "subcutaneous", "nasal" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "ghrp-2", "ghrp 2", "ghrp2", "Pralmorelin", "Pralmorelin hydrochloride", "KP-102", "hunger", "sleep", "gh pulse", "empty stomach", "compounding", "IGF-1", "prolactin" ], "feel_search": [ "hunger", "sleep", "gh pulse", "empty stomach", "compounding", "IGF-1", "prolactin" ], "summary": "GHRP-2, or pralmorelin, is a growth-hormone-releasing peptide; bodybuilding users discuss it for appetite, recovery and growth-hormone pulses.", "search_blob": "ghrp-2 ghrp-2 pralmorelin kp-102 pralmorelin hydrochloride kp-102ln gpa 748 gpa-748 way-gpa-748 ghrp kaken 100 growth hormone-releasing peptide-2 ghrp2 ghrp 2 d-ala-d-2nal-ala-trp-d-phe-lys-nh2 ghrp-2 ghrp 2 ghrp2 pralmorelin pralmorelin hydrochloride kp-102 hunger sleep gh pulse empty stomach compounding igf-1 prolactin muscle growth appetite recovery fat loss discussion appetite / hard-gainer bulk body composition performance sleep (discussed) anti-aging discussion igf-1 elevation (discussed) gh deficiency diagnostic (japan, clinical) lean recomp with controllable hunger vs ghrp-6 hunger sleep gh pulse empty stomach compounding igf-1 prolactin ghrp-2, or pralmorelin, is a growth-hormone-releasing peptide; bodybuilding users discuss it for appetite, recovery and growth-hormone pulses. hunger, brief warmth or drowsiness are reported soon after use, with sleep changes in some logs. the appetite sensation is distinct from a measured growth-hormone response. ghrp-2 (pralmorelin) is a peptide people look up for appetite. hunger wave often peaks ~20\u201330 min post-shot; minority report flush, warmth, lightheaded rush, or mild drowsiness. usually stacked with a ghrh analog. empty stomach, 1\u20133 pins a day. growth hormone axis peptide systemic systemic \u2014 ghrelin-receptor agonist discussed for pituitary gh pulses, appetite, recovery and body composition; not local joint or muscle targeting. systemic whole-body circulating", "legal_class": null }, { "id": 32, "slug": "ghrp-6", "name": "GHRP-6", "aliases": [ "Growth hormone releasing peptide-6", "Growth hormone-releasing hexapeptide", "GH-releasing peptide-6", "GHRP 6", "GHRP6", "His-D-Trp-Ala-Trp-D-Phe-Lys-NH2", "HwAWfK-NH2", "SK&F 110679", "SKF-110679", "SKF 110679", "Hexapeptide-2", "U 75799E" ], "type": "Peptide", "category": "Growth hormone axis", "goals_use_cases": [ "muscle growth", "appetite", "recovery", "appetite / hard-gainer bulk", "body composition", "performance", "anti-catabolism (discussed)", "sleep adjacency (discussed)", "IGF-1 support (discussed)", "surplus adherence (hunger as lever)", "lean bulk when ravenous appetite is wanted on purpose" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "ghrp-6", "ghrp 6", "ghrp6", "Growth hormone releasing peptide-6", "Growth hormone-releasing hexapeptide", "GH-releasing peptide-6", "hunger", "ravenous", "gh pulse", "empty stomach", "compounding", "IGF-1", "cut" ], "feel_search": [ "hunger", "ravenous", "gh pulse", "empty stomach", "compounding", "IGF-1", "cut" ], "summary": "GHRP-6 is a growth-hormone-releasing peptide known in bodybuilding discussions for strong hunger; appetite can be the desired effect or the drawback.", "search_blob": "ghrp-6 ghrp-6 growth hormone releasing peptide-6 growth hormone-releasing hexapeptide gh-releasing peptide-6 ghrp 6 ghrp6 his-d-trp-ala-trp-d-phe-lys-nh2 hwawfk-nh2 sk&f 110679 skf-110679 skf 110679 hexapeptide-2 u 75799e ghrp-6 ghrp 6 ghrp6 growth hormone releasing peptide-6 growth hormone-releasing hexapeptide gh-releasing peptide-6 hunger ravenous gh pulse empty stomach compounding igf-1 cut muscle growth appetite recovery appetite / hard-gainer bulk body composition performance anti-catabolism (discussed) sleep adjacency (discussed) igf-1 support (discussed) surplus adherence (hunger as lever) lean bulk when ravenous appetite is wanted on purpose hunger ravenous gh pulse empty stomach compounding igf-1 cut ghrp-6 is a growth-hormone-releasing peptide known in bodybuilding discussions for strong hunger; appetite can be the desired effect or the drawback. a strong hunger wave is the most recognizable report, sometimes with warmth, head-rush or site sting. water retention, vivid dreams, nausea or fatigue also appear in longer or stacked logs. ghrp-6 is a peptide people look up for appetite. hunger wave frequently lasts ~30\u201360+ min; many plan a meal in the post-dose window rather than fighting it. bulk logs frame the hunger as a feature; cut logs often find it disruptive. 100 mcg is the saturation lore. growth hormone axis peptide systemic systemic \u2014 ghrelin-receptor peptide discussed for gh pulses, appetite, recovery and body composition; not local joint or muscle targeting. systemic whole-body circulating", "legal_class": null }, { "id": 33, "slug": "hexarelin", "name": "Hexarelin", "aliases": [ "Examorelin", "HEX", "EP-23905", "MF-6003", "His-D-2-methyl-Trp-Ala-Trp-D-Phe-Lys-NH2", "Hexareline (misspelling)" ], "type": "Peptide", "category": "Growth hormone axis", "goals_use_cases": [ "muscle growth", "recovery", "performance", "body composition / recomp", "GH pulse amplitude (acute)", "anti-aging discussion", "cardiac / cardioprotective research interest", "fat loss (discussed, usually secondary to GH/IGF talk)", "sleep quality (mixed reports)", "bone / collagen marker interest (sparse clinical signals)" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "hexarelin", "Examorelin", "HEX", "EP-23905", "MF-6003", "His-D-2-methyl-Trp-Ala-Trp-D-Phe-Lys-NH2", "cortisol", "prolactin", "gh pulse", "strong", "empty stomach", "compounding", "IGF-1", "desensitization" ], "feel_search": [ "cortisol", "prolactin", "gh pulse", "strong", "empty stomach", "compounding", "IGF-1", "desensitization" ], "summary": "Hexarelin (examorelin) is a synthetic growth-hormone-releasing peptide, discussed for recovery and physique changes.", "search_blob": "hexarelin hexarelin examorelin hex ep-23905 mf-6003 his-d-2-methyl-trp-ala-trp-d-phe-lys-nh2 hexareline (misspelling) hexarelin examorelin hex ep-23905 mf-6003 his-d-2-methyl-trp-ala-trp-d-phe-lys-nh2 cortisol prolactin gh pulse strong empty stomach compounding igf-1 desensitization muscle growth recovery performance body composition / recomp gh pulse amplitude (acute) anti-aging discussion cardiac / cardioprotective research interest fat loss (discussed, usually secondary to gh/igf talk) sleep quality (mixed reports) bone / collagen marker interest (sparse clinical signals) cortisol prolactin gh pulse strong empty stomach compounding igf-1 desensitization hexarelin (examorelin) is a synthetic growth-hormone-releasing peptide, discussed for recovery and physique changes. reports include brief warmth, heaviness or fatigue, mild hunger, sleep changes, or little immediate effect. recovery and tingling reports often come from multi-drug stacks. hexarelin is a peptide people look up for muscle and recovery. hunger rise often described as milder than ghrp-6; still present for some users. people treat 100 mcg as the middle. not the first ghrp in careful threads. growth hormone axis peptide systemic systemic \u2014 pituitary ghs-r1a (ghrelin receptor) agonist that triggers whole-body gh/igf-1 axis pulses plus modest acth/cortisol and prolactin spillover. systemic whole-body circulating", "legal_class": null }, { "id": 34, "slug": "mod-grf-1-29", "name": "Mod GRF 1-29", "aliases": [ "CJC-1295 without DAC", "Modified GRF 1-29", "CJC no DAC", "CJC-1295 no DAC", "Mod GRF", "Mod GRF (1-29)", "tetra-substituted GRF 1-29", "tetrasubstituted GRF (1-29)", "CJC-1295 (no DAC)", "CJC-1295 No-DAC", "modGRF" ], "type": "Peptide", "category": "Growth hormone axis", "goals_use_cases": [ "muscle growth", "sleep", "recovery", "fat loss", "performance", "body recomposition", "anti-aging (discussed)", "IGF-1 support (discussed)", "lean mass preservation", "skin / recovery adjacency", "nocturnal GH pulse amplification" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "mod-grf-1-29", "mod grf 1 29", "modgrf129", "Mod GRF 1-29", "CJC-1295 without DAC", "CJC-1295 no DAC", "sleep", "cjc no dac", "recovery" ], "feel_search": [ "sleep", "cjc no dac", "recovery" ], "summary": "Mod GRF 1-29 is a short-acting GHRH peptide analog, often sold as CJC-1295 without DAC and paired with ipamorelin for sleep or recovery.", "search_blob": "mod grf 1-29 mod-grf-1-29 cjc-1295 without dac modified grf 1-29 cjc no dac cjc-1295 no dac mod grf mod grf (1-29) tetra-substituted grf 1-29 tetrasubstituted grf (1-29) cjc-1295 (no dac) cjc-1295 no-dac modgrf mod-grf-1-29 mod grf 1 29 modgrf129 mod grf 1-29 cjc-1295 without dac cjc-1295 no dac sleep cjc no dac recovery muscle growth sleep recovery fat loss performance body recomposition anti-aging (discussed) igf-1 support (discussed) lean mass preservation skin / recovery adjacency nocturnal gh pulse amplification sleep cjc no dac recovery mod grf 1-29 is a short-acting ghrh peptide analog, often sold as cjc-1295 without dac and paired with ipamorelin for sleep or recovery. some describe a brief flush, better sleep or easier recovery; others notice nothing after weeks. most reports involve ipamorelin blends, so mod grf's contribution is unclear. mod grf 1-29 is a peptide people look up for muscle. easier next-day readiness and less soreness after several weeks \u2014 heavily confounded by sleep, training volume, and co-stacks. 100 mcg is saturation lore. don\u2019t use dac weekly charts here. growth hormone axis peptide systemic systemic \u2014 short-acting ghrh analog; whole-body gh pulses via pituitary ghrh receptors, not local tissue repair. systemic whole-body circulating", "legal_class": null }, { "id": 35, "slug": "peg-mgf", "name": "PEG-MGF", "aliases": [ "Pegylated Mechano Growth Factor", "PEG MGF", "PEGylated Mechano Growth Factor", "PEG-MGF peptide", "Pegylated MGF", "PEGylated MGF", "Peg-MGF", "PEGylated IGF-1Ec (community shorthand)", "PEG-IGF-1Ec (loose forum synonym \u2014 not always the same product)", "Mechano Growth Factor (pegylated form)" ], "type": "Peptide", "category": "Growth factors", "goals_use_cases": [ "muscle growth", "recovery", "performance", "muscle growth / hypertrophy (discussed)", "recovery / training continuity", "post-workout muscle repair talk", "satellite-cell activation / hyperplasia lore", "soft-tissue / muscle-strain recovery (discussed)", "injury-adjacent downtime reduction talk", "localized / site-focused repair discussion", "stack partner with IGF-1 LR3 (\u201ctwo-wave\u201d growth-factor lore)" ], "delivery_methods": [ "intramuscular", "subcutaneous" ], "discussion_popularity": "High", "reach": "Mixed", "misspellings_search_terms": [ "peg-mgf", "peg mgf", "pegmgf", "Pegylated Mechano Growth Factor", "PEG-MGF peptide", "Pegylated MGF", "soreness", "recovery", "pumps" ], "feel_search": [ "soreness", "recovery", "pumps" ], "summary": "PEG-MGF is a label for a modified MGF E-domain peptide discussed for muscle recovery; it is distinct from full-length PEG-IGF-1.", "search_blob": "peg-mgf peg-mgf pegylated mechano growth factor peg mgf pegylated mechano growth factor peg-mgf peptide pegylated mgf pegylated mgf peg-mgf pegylated igf-1ec (community shorthand) peg-igf-1ec (loose forum synonym \u2014 not always the same product) mechano growth factor (pegylated form) peg-mgf peg mgf pegmgf pegylated mechano growth factor peg-mgf peptide pegylated mgf soreness recovery pumps muscle growth recovery performance muscle growth / hypertrophy (discussed) recovery / training continuity post-workout muscle repair talk satellite-cell activation / hyperplasia lore soft-tissue / muscle-strain recovery (discussed) injury-adjacent downtime reduction talk localized / site-focused repair discussion stack partner with igf-1 lr3 (\u201ctwo-wave\u201d growth-factor lore) soreness recovery pumps peg-mgf is a label for a modified mgf e-domain peptide discussed for muscle recovery; it is distinct from full-length peg-igf-1. one account described modest recovery with subq use; another preferred use in the trained muscle. those reports disagree about route. peg-mgf is a peptide people look up for muscle. recovery continuity / less next-day noise is the earliest commonly claimed signal \u2014 still confounded. usually training days, 2\u20133\u00d7 a week. site reactions are common. growth factors peptide mixed mixed in discussion: subq use and local im placement both appear; human distribution and a multi-day half-life remain unverified. mixed local systemic", "legal_class": null }, { "id": 36, "slug": "hgh", "name": "Human Growth Hormone (somatropin)", "aliases": [ "HGH", "rhGH", "somatropin", "Genotropin-class discussion", "recombinant human growth hormone", "191aa GH", "191 AA HGH", "somatotrophin / somatotropin (legacy spellings)", "somatrem / met-HGH / 192aa (historical / gray-market contrast)", "Norditropin-class discussion", "Omnitrope-class discussion", "Humatrope-class discussion", "Nutropin-class discussion", "Serostim-class discussion (HIV wasting context)", "pharma GH / \u201cpharma grade\u201d talk" ], "type": "Peptide", "category": "Growth hormone axis", "goals_use_cases": [ "muscle growth", "fat loss", "recovery", "anti-aging discussion", "muscle growth / lean mass (discussed; fluid confound large)", "fat loss / lipolysis / body recomposition", "recovery / training continuity (discussed)", "anti-aging / wellness-clinic discussion", "skin / collagen / \u201cyouthful\u201d look (discussed)", "sleep quality (evening-dose talk; mixed)", "IGF-1 elevation support (discussed)", "performance / aesthetic physique (off-label community)", "clinical adult GH deficiency (GHD) replacement context", "HIV wasting / cachexia (approved somatropin indication context)", "joint / connective-tissue recovery lore (anecdotal; confounded)", "stack amplifier with AAS \u00b1 insulin \u00b1 IGF-1 (community)" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "hgh", "Human Growth Hormone (somatropin)", "human-growth-hormone-(somatropin)", "rhGH", "somatropin", "recombinant human growth hormone", "sleep", "water retention", "carpal", "fat loss", "empty stomach", "compounding", "IGF-1", "split dose", "import alert", "kits" ], "feel_search": [ "sleep", "water retention", "carpal", "fat loss", "hgh", "empty stomach", "compounding", "IGF-1", "split dose", "import alert", "kits" ], "summary": "HGH here means recombinant human growth hormone (somatropin), discussed for hormone replacement, physique changes and recovery.", "search_blob": "human growth hormone (somatropin) hgh hgh rhgh somatropin genotropin-class discussion recombinant human growth hormone 191aa gh 191 aa hgh somatotrophin / somatotropin (legacy spellings) somatrem / met-hgh / 192aa (historical / gray-market contrast) norditropin-class discussion omnitrope-class discussion humatrope-class discussion nutropin-class discussion serostim-class discussion (hiv wasting context) pharma gh / \u201cpharma grade\u201d talk hgh human growth hormone (somatropin) human-growth-hormone-(somatropin) rhgh somatropin recombinant human growth hormone sleep water retention carpal fat loss empty stomach compounding igf-1 split dose import alert kits muscle growth fat loss recovery anti-aging discussion muscle growth / lean mass (discussed; fluid confound large) fat loss / lipolysis / body recomposition recovery / training continuity (discussed) anti-aging / wellness-clinic discussion skin / collagen / \u201cyouthful\u201d look (discussed) sleep quality (evening-dose talk; mixed) igf-1 elevation support (discussed) performance / aesthetic physique (off-label community) clinical adult gh deficiency (ghd) replacement context hiv wasting / cachexia (approved somatropin indication context) joint / connective-tissue recovery lore (anecdotal; confounded) stack amplifier with aas \u00b1 insulin \u00b1 igf-1 (community) sleep water retention carpal fat loss hgh empty stomach compounding igf-1 split dose import alert kits hgh here means recombinant human growth hormone (somatropin), discussed for hormone replacement, physique changes and recovery. some hgh users describe pumps or gradual appearance changes; others mainly notice numb or painful hands. the reviewed fat-loss story also involved clenbuterol, yohimbine and fasted cardio. hgh (somatropin) is a peptide for muscle. multi-week logs claim easier session-to-session recovery and joint comfort \u2014 heavily confounded by sleep, diet, aas, and expectancy. iu labels on gray vials are shaky. ~3 iu \u2248 1 mg is the usual conversion people use. growth hormone axis peptide systemic systemic \u2014 binds gh receptors widely; hepatic igf-1 and whole-body metabolic/body-composition effects. systemic whole-body circulating", "legal_class": null }, { "id": 37, "slug": "cagrilintide", "name": "Cagrilintide", "aliases": [ "Cagri", "amylin analogue discussion", "Cagrilintide acetate (research/compounded discussions)", "Long-acting amylin analogue", "Amylin receptor agonist (class framing)", "DACRA (dual amylin and calcitonin receptor agonist framing)", "AM833 / AM-833 (developmental / research designation)", "NN9838 / NN 9838 (developmental designation)", "NNC0174-0833 / NNC-0174-0833 (Novo compound code)", "CagriSema component (fixed-dose combo with semaglutide)" ], "type": "Peptide", "category": "Metabolic / GLP-1 class", "goals_use_cases": [ "fat loss", "appetite control", "satiety / meal-size reduction", "weight management / obesity", "food noise reduction (discussed)", "metabolic health", "GLP-1 combination interest (CagriSema)", "amylin-pathway / second-axis satiety research", "body recomposition (confounded by lean-mass risk under low intake)", "type 2 diabetes weight + glycemic co-interest (combo programs)", "DIY multi-agonist stack talk (cagri + sema / tirz / reta)", "GLP-1 intolerance bridge talk (mono cagri framed as lower-vomiting option in meta-analyses)" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "cagrilintide", "Cagri", "Cagrilintide acetate (research/compounded discussions)", "Long-acting amylin analogue", "Amylin receptor agonist (class framing)", "DACRA (dual amylin and calcitonin receptor agonist framing)", "fullness", "appetite", "nausea", "amylin", "food noise", "alcohol", "plateau", "compounding", "research use only", "fatigue", "split dose" ], "feel_search": [ "fullness", "appetite", "nausea", "amylin", "food noise", "alcohol", "plateau", "compounding", "research use only", "fatigue", "split dose" ], "summary": "Cagrilintide is a long-acting amylin analogue investigated for appetite and weight management, distinct from GLP-1 drugs.", "search_blob": "cagrilintide cagrilintide cagri amylin analogue discussion cagrilintide acetate (research/compounded discussions) long-acting amylin analogue amylin receptor agonist (class framing) dacra (dual amylin and calcitonin receptor agonist framing) am833 / am-833 (developmental / research designation) nn9838 / nn 9838 (developmental designation) nnc0174-0833 / nnc-0174-0833 (novo compound code) cagrisema component (fixed-dose combo with semaglutide) cagrilintide cagri cagrilintide acetate (research/compounded discussions) long-acting amylin analogue amylin receptor agonist (class framing) dacra (dual amylin and calcitonin receptor agonist framing) fullness appetite nausea amylin food noise alcohol plateau compounding research use only fatigue split dose fat loss appetite control satiety / meal-size reduction weight management / obesity food noise reduction (discussed) metabolic health glp-1 combination interest (cagrisema) amylin-pathway / second-axis satiety research body recomposition (confounded by lean-mass risk under low intake) type 2 diabetes weight + glycemic co-interest (combo programs) diy multi-agonist stack talk (cagri + sema / tirz / reta) glp-1 intolerance bridge talk (mono cagri framed as lower-vomiting option in meta-analyses) fullness appetite nausea amylin food noise alcohol plateau compounding research use only fatigue split dose cagrilintide is a long-acting amylin analogue investigated for appetite and weight management, distinct from glp-1 drugs. first-dose accounts range from little trouble to several days of nausea or dry heaves. many writers also use tirzepatide, making the combination important. cagrilintide is a peptide people look up for fat loss and appetite. some report early \u2018full after a few bites\u2019 even at micro starts. gi sides like the glp class. 2.4 mg weekly is the number people quote. metabolic / glp-1 class peptide systemic systemic \u2014 a long-acting amylin analogue studied for satiety and weight management; not a local tissue-repair peptide. systemic whole-body circulating", "legal_class": null }, { "id": 38, "slug": "cagrisema", "name": "CagriSema", "aliases": [ "CagriSema", "cagrilintide/semaglutide combo", "CagriSema (cagrilintide + semaglutide)", "cagrilintide\u2013semaglutide", "Cagri Sema", "cagri-sema", "NN9838 + semaglutide coadministration (developmental discussion)", "amylin + GLP-1 fixed-dose combination (Novo)" ], "type": "Peptide", "category": "Metabolic / GLP-1 class", "goals_use_cases": [ "fat loss", "appetite control", "metabolic health", "fat loss / chronic weight management", "appetite control and meal-size reduction", "food-noise reduction (dual pathway)", "metabolic health / cardiometabolic markers", "type 2 diabetes\u2013adjacent glycemic discussion", "satiety dual-pathway (amylin/calcitonin + GLP-1)", "post-sema plateau add-on curiosity (community)", "body recomposition interest (confounded; lean mass still at risk with large deficits)", "obesity research (investigational fixed-dose combo)" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "cagrisema", "CagriSema (cagrilintide + semaglutide)", "cagrilintide/semaglutide combo", "cagrilintide\u2013semaglutide", "Cagri Sema", "cagri-sema", "food noise", "nausea", "fat loss", "sema", "dual chamber", "blended vial", "brain fog", "shot day", "food baby" ], "feel_search": [ "food noise", "nausea", "fat loss", "sema", "dual chamber", "blended vial", "brain fog", "shot day", "food baby" ], "summary": "CagriSema is an investigational fixed combination of cagrilintide and semaglutide, combining amylin and GLP-1 pathways for weight management.", "search_blob": "cagrisema cagrisema cagrisema cagrilintide/semaglutide combo cagrisema (cagrilintide + semaglutide) cagrilintide\u2013semaglutide cagri sema cagri-sema nn9838 + semaglutide coadministration (developmental discussion) amylin + glp-1 fixed-dose combination (novo) cagrisema cagrisema (cagrilintide + semaglutide) cagrilintide/semaglutide combo cagrilintide\u2013semaglutide cagri sema cagri-sema food noise nausea fat loss sema dual chamber blended vial brain fog shot day food baby fat loss appetite control metabolic health fat loss / chronic weight management appetite control and meal-size reduction food-noise reduction (dual pathway) metabolic health / cardiometabolic markers type 2 diabetes\u2013adjacent glycemic discussion satiety dual-pathway (amylin/calcitonin + glp-1) post-sema plateau add-on curiosity (community) body recomposition interest (confounded; lean mass still at risk with large deficits) obesity research (investigational fixed-dose combo) food noise nausea fat loss sema dual chamber blended vial brain fog shot day food baby cagrisema is an investigational fixed combination of cagrilintide and semaglutide, combining amylin and glp-1 pathways for weight management. a blinded participant reports fullness within hours, then burps, hiccups and reflux. they did not know whether they received the combination, semaglutide or placebo. cagrisema is a peptide people look up for fat loss. users describe earlier fullness and less grazing. a lot of people never hit the full dose because of stomach sides. that\u2019s in the trial story too. metabolic / glp-1 class peptide systemic systemic \u2014 investigational cagrilintide plus semaglutide, studied for appetite, weight and glycemic effects; trial pens differ from gray blends. systemic whole-body circulating", "legal_class": null }, { "id": 39, "slug": "dsip", "name": "DSIP", "aliases": [ "Delta Sleep-Inducing Peptide", "Delta-sleep-inducing peptide", "DSIP nonapeptide", "Emideltide (compounding / INN-style name)", "Deltaran (Russian DSIP-containing preparation; not identical pure research vial)", "Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu", "WAGGDASGE (sequence shorthand)" ], "type": "Peptide", "category": "Sleep / mood", "goals_use_cases": [ "sleep", "stress", "recovery", "deep / slow-wave (delta) sleep", "sleep onset / latency", "sleep efficiency / fewer night arousals", "stress / evening cortisol narratives", "recovery / next-day readiness", "jet lag / shift-work schedule disruption", "sleep architecture interest (wearables / EEG talk)", "vivid / lucid dream interest (side-effect or goal, split)", "chronic insomnia research history", "opiate / alcohol withdrawal historical research (not modern primary bro use)", "pain / stress-axis co-interest (secondary literature)", "narcolepsy / disturbed-sleep historical exploration (sparse)" ], "delivery_methods": [ "subcutaneous", "nasal" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "dsip", "Delta Sleep-Inducing Peptide", "Delta-sleep-inducing peptide", "DSIP nonapeptide", "Emideltide (compounding / INN-style name)", "Deltaran (Russian DSIP-containing preparation; not identical pure research vial)", "sleep", "deep sleep", "insomnia", "oura" ], "feel_search": [ "sleep", "deep sleep", "insomnia", "oura" ], "summary": "DSIP, or delta sleep-inducing peptide, is an experimental nine-amino-acid peptide discussed for sleep; the name does not guarantee sedation.", "search_blob": "dsip dsip delta sleep-inducing peptide delta-sleep-inducing peptide dsip nonapeptide emideltide (compounding / inn-style name) deltaran (russian dsip-containing preparation; not identical pure research vial) trp-ala-gly-gly-asp-ala-ser-gly-glu waggdasge (sequence shorthand) dsip delta sleep-inducing peptide delta-sleep-inducing peptide dsip nonapeptide emideltide (compounding / inn-style name) deltaran (russian dsip-containing preparation; not identical pure research vial) sleep deep sleep insomnia oura sleep stress recovery deep / slow-wave (delta) sleep sleep onset / latency sleep efficiency / fewer night arousals stress / evening cortisol narratives recovery / next-day readiness jet lag / shift-work schedule disruption sleep architecture interest (wearables / eeg talk) vivid / lucid dream interest (side-effect or goal, split) chronic insomnia research history opiate / alcohol withdrawal historical research (not modern primary bro use) pain / stress-axis co-interest (secondary literature) narcolepsy / disturbed-sleep historical exploration (sparse) sleep deep sleep insomnia oura dsip, or delta sleep-inducing peptide, is an experimental nine-amino-acid peptide discussed for sleep; the name does not guarantee sedation. one forum user describes dozing after about half an hour and waking refreshed; another community account reports no sleep benefit at all. dsip is a sleep-related peptide people discuss for deeper rest. \u201cinception,\u201d multi-layer, and occasional lucid dreams; some chase this, others find it sleep-fragmenting. old studies were iv. modern gray-market talk is a small subq mcg pin. don\u2019t treat those as the same. sleep / mood peptide systemic systemic \u2014 whole-system sleep/stress neuromodulation and neuroendocrine talk; not local tissue repair. systemic whole-body circulating", "legal_class": null }, { "id": 40, "slug": "kisspeptin-10", "name": "Kisspeptin-10", "aliases": [ "Kisspeptin", "Kp-10", "Metastin fragment discussion", "KP-10", "Kisspeptin 10", "Kisspeptin-10 amide", "Metastin (45-54)", "Metastin fragment (Kp-10)", "KISS-1 (112-121)", "Human metastin 45-54", "YNWNSFGLRF-NH2" ], "type": "Peptide", "category": "Reproductive & endocrine peptides", "goals_use_cases": [ "libido", "fertility discussion", "hormone axis", "LH / FSH stimulation research", "testosterone support (upstream, discussed)", "HPG axis research", "HSDD / low desire research context", "PCT / post-suppression recovery talk", "sexual desire (central pathways, discussed)", "TRT adjunct axis talk", "hypothalamic amenorrhea research context", "secondary hypogonadism discussion" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "kisspeptin-10", "kisspeptin 10", "kisspeptin10", "Kisspeptin", "Kp-10", "Kisspeptin-10 amide", "libido", "lh", "fertility", "hormone", "compounding", "estradiol", "hCG", "PCT" ], "feel_search": [ "libido", "lh", "fertility", "hormone", "compounding", "estradiol", "hCG", "PCT" ], "summary": "Kisspeptin-10 is a reproductive-signaling peptide that activates the GnRH hormone pathway, discussed for fertility, libido and sexual function.", "search_blob": "kisspeptin-10 kisspeptin-10 kisspeptin kp-10 metastin fragment discussion kp-10 kisspeptin 10 kisspeptin-10 amide metastin (45-54) metastin fragment (kp-10) kiss-1 (112-121) human metastin 45-54 ynwnsfglrf-nh2 kisspeptin-10 kisspeptin 10 kisspeptin10 kisspeptin kp-10 kisspeptin-10 amide libido lh fertility hormone compounding estradiol hcg pct libido fertility discussion hormone axis lh / fsh stimulation research testosterone support (upstream, discussed) hpg axis research hsdd / low desire research context pct / post-suppression recovery talk sexual desire (central pathways, discussed) trt adjunct axis talk hypothalamic amenorrhea research context secondary hypogonadism discussion libido lh fertility hormone compounding estradiol hcg pct kisspeptin-10 is a reproductive-signaling peptide that activates the gnrh hormone pathway, discussed for fertility, libido and sexual function. one pssd account described easier orgasm after about a week, with partial improvements over the following weeks. brain fog and motivation did not improve; the author explicitly did not describe a cure. kisspeptin-10 is a peptide people look up for libido. watch sleep, mood, libido, morning erections, and injection-site tolerance; early subjective change is inconsistent. don\u2019t copy kisspeptin-54 iv desire trials onto a kp-10 vial. reproductive & endocrine peptides peptide systemic systemic \u2014 upstream hpg signal (kisspeptin \u2192 kiss1r on gnrh neurons \u2192 gnrh \u2192 lh/fsh \u2192 gonadal sex steroids). systemic whole-body circulating", "legal_class": null }, { "id": 41, "slug": "gonadorelin", "name": "Gonadorelin", "aliases": [ "GnRH", "Lutrepulse-class discussion", "Gonadotropin-releasing hormone", "LHRH", "Luteinizing hormone-releasing hormone", "Gonadorelin acetate", "Gonadorelin hydrochloride", "Factrel (clinical brand discussion; US product historically discontinued for commercial reasons)", "Lutrepulse / Lutrelef-class discussion", "pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2", "Pyr-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2" ], "type": "Peptide", "category": "Reproductive & endocrine peptides", "goals_use_cases": [ "hormone axis", "fertility discussion", "libido", "TRT adjunct (discussed)", "HPTA support (discussed)", "pituitary stimulation (diagnostic framing)", "testicular maintenance / anti-atrophy (discussed)", "post-AAS recovery narratives", "PCT discussion", "hypogonadotropic hypogonadism research context", "hCG alternative (access/shortage/compounding-driven)", "functional hypothalamic amenorrhea / ovulation induction (clinical pump context)", "spermatogenesis induction (pulsatile pump / CHH literature)" ], "delivery_methods": [ "subcutaneous", "pulsatile pump (clinical discussion)" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "gonadorelin", "GnRH", "Gonadotropin-releasing hormone", "LHRH", "Luteinizing hormone-releasing hormone", "Gonadorelin acetate", "hormone axis", "fertility discussion", "libido", "trt adjunct (discussed)", "hpta support (discussed)", "pituitary stimulation (diagnostic framing)" ], "feel_search": [ "hormone axis", "fertility discussion", "libido", "trt adjunct (discussed)", "hpta support (discussed)", "pituitary stimulation (diagnostic framing)" ], "summary": "Gonadorelin is synthetic GnRH, a hormone signal to the pituitary; it is discussed for fertility and as a clinic-offered hCG alternative.", "search_blob": "gonadorelin gonadorelin gnrh lutrepulse-class discussion gonadotropin-releasing hormone lhrh luteinizing hormone-releasing hormone gonadorelin acetate gonadorelin hydrochloride factrel (clinical brand discussion; us product historically discontinued for commercial reasons) lutrepulse / lutrelef-class discussion pglu-his-trp-ser-tyr-gly-leu-arg-pro-gly-nh2 pyr-his-trp-ser-tyr-gly-leu-arg-pro-gly-nh2 gonadorelin gnrh gonadotropin-releasing hormone lhrh luteinizing hormone-releasing hormone gonadorelin acetate hormone axis fertility discussion libido trt adjunct (discussed) hpta support (discussed) pituitary stimulation (diagnostic framing) hormone axis fertility discussion libido trt adjunct (discussed) hpta support (discussed) pituitary stimulation (diagnostic framing) testicular maintenance / anti-atrophy (discussed) post-aas recovery narratives pct discussion hypogonadotropic hypogonadism research context hcg alternative (access/shortage/compounding-driven) functional hypothalamic amenorrhea / ovulation induction (clinical pump context) spermatogenesis induction (pulsatile pump / chh literature) hormone axis fertility discussion libido trt adjunct (discussed) hpta support (discussed) pituitary stimulation (diagnostic framing) gonadorelin is synthetic gnrh, a hormone signal to the pituitary; it is discussed for fertility and as a clinic-offered hcg alternative. gonadorelin is a peptide people look up for libido. some feel better desire/\u201cfullness\u201d when labs move; many report no subjective change despite dosing. reproductive & endocrine peptides peptide systemic systemic: synthetic native-sequence decapeptide gnrh hits pituitary gnrh receptors \u2192 lh + fsh \u2192 gonads. systemic whole-body circulating", "legal_class": null }, { "id": 42, "slug": "hcg", "name": "hCG", "aliases": [ "Human chorionic gonadotropin", "Pregnyl-class discussion", "HCG", "Pregnyl", "Novarel", "Profasi (historical urinary brand discussion)", "Ovidrel / choriogonadotropin alfa (recombinant)", "r-hCG", "u-hCG", "chorionic gonadotropin", "beta-hCG (assay/doping talk)", "Gonasi (regional brand talk)", "choriogonadotropin alfa" ], "type": "Peptide", "category": "Reproductive & endocrine peptides", "goals_use_cases": [ "hormone axis", "fertility discussion", "PCT discussion", "TRT fertility preservation", "testicular function / anti-atrophy", "libido", "hypogonadism discussion", "spermatogenesis support", "on-cycle testicular maintenance (AAS talk)", "female ART ovulation / oocyte-maturation trigger", "hypogonadotropic hypogonadism induction", "hCG monotherapy (selected secondary hypogonadism)", "cryptorchidism / puberty induction (historical clinical)", "weight-loss diet lore (FDA-warned; not a supported use)" ], "delivery_methods": [ "subcutaneous", "intramuscular" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "hcg", "Human chorionic gonadotropin", "Pregnyl", "Novarel", "Profasi (historical urinary brand discussion)", "Ovidrel / choriogonadotropin alfa (recombinant)", "hormone axis", "fertility discussion", "pct discussion", "trt fertility preservation", "testicular function / anti-atrophy", "libido" ], "feel_search": [ "hormone axis", "fertility discussion", "pct discussion", "trt fertility preservation", "testicular function / anti-atrophy", "libido" ], "summary": "hCG is a pregnancy hormone that mimics LH at the testes; it is discussed for fertility and maintaining testicular function during TRT.", "search_blob": "hcg hcg human chorionic gonadotropin pregnyl-class discussion hcg pregnyl novarel profasi (historical urinary brand discussion) ovidrel / choriogonadotropin alfa (recombinant) r-hcg u-hcg chorionic gonadotropin beta-hcg (assay/doping talk) gonasi (regional brand talk) choriogonadotropin alfa hcg human chorionic gonadotropin pregnyl novarel profasi (historical urinary brand discussion) ovidrel / choriogonadotropin alfa (recombinant) hormone axis fertility discussion pct discussion trt fertility preservation testicular function / anti-atrophy libido hormone axis fertility discussion pct discussion trt fertility preservation testicular function / anti-atrophy libido hypogonadism discussion spermatogenesis support on-cycle testicular maintenance (aas talk) female art ovulation / oocyte-maturation trigger hypogonadotropic hypogonadism induction hcg monotherapy (selected secondary hypogonadism) cryptorchidism / puberty induction (historical clinical) weight-loss diet lore (fda-warned; not a supported use) hormone axis fertility discussion pct discussion trt fertility preservation testicular function / anti-atrophy libido hcg is a pregnancy hormone that mimics lh at the testes; it is discussed for fertility and maintaining testicular function during trt. hcg is a peptide people look up for fertility. low-dose adjunct commonly linked to less atrophy / better fullness vs trt alone. reproductive & endocrine peptides peptide systemic systemic \u2014 lh/cg-receptor agonist on leydig cells (males) and theca/granulosa (females); raises gonadal steroids axis-wide, not a local cosmetic peptide. systemic whole-body circulating", "legal_class": null }, { "id": 43, "slug": "oxytocin", "name": "Oxytocin", "aliases": [ "OT", "love hormone (colloquial)", "OXT", "cuddle hormone (colloquial)", "Syntocinon (pharmaceutical brand contexts)", "Pitocin (pharmaceutical brand / labor-induction contexts)", "oxytocin acetate (research-vial labeling)", "intranasal oxytocin (INOXT / IN-OT research shorthand)" ], "type": "Peptide", "category": "Neuropeptides", "goals_use_cases": [ "social bonding discussion", "mood", "libido", "anxiety discussion", "mood / affiliative affect", "libido and intimacy", "anxiety / social-threat reactivity (discussed)", "pair bonding / relationship closeness (discussed)", "sexual function and orgasm quality (discussed)", "trust / social cognition research", "stress-hormone response in social contexts (research)", "chronic pain adjunct research (intranasal multi-day protocols)", "ASD social outcomes research (mixed / large null trial)", "PTSD / trauma-related social comfort (compounding clinic talk)" ], "delivery_methods": [ "nasal", "subcutaneous" ], "discussion_popularity": "Medium", "reach": "Mixed", "misspellings_search_terms": [ "oxytocin", "OT", "OXT", "love hormone (colloquial)", "cuddle hormone (colloquial)", "Syntocinon (pharmaceutical brand contexts)", "social bonding discussion", "mood / affiliative affect", "libido and intimacy", "anxiety / social-threat reactivity (discussed)", "pair bonding / relationship closeness (discussed)", "sexual function and orgasm quality (discussed)" ], "feel_search": [ "social bonding discussion", "mood / affiliative affect", "libido and intimacy", "anxiety / social-threat reactivity (discussed)", "pair bonding / relationship closeness (discussed)", "sexual function and orgasm quality (discussed)" ], "summary": "Oxytocin is a natural hormone and peptide; nasal products are discussed for closeness and social comfort, separate from its obstetric use.", "search_blob": "oxytocin oxytocin ot love hormone (colloquial) oxt cuddle hormone (colloquial) syntocinon (pharmaceutical brand contexts) pitocin (pharmaceutical brand / labor-induction contexts) oxytocin acetate (research-vial labeling) intranasal oxytocin (inoxt / in-ot research shorthand) oxytocin ot oxt love hormone (colloquial) cuddle hormone (colloquial) syntocinon (pharmaceutical brand contexts) social bonding discussion mood / affiliative affect libido and intimacy anxiety / social-threat reactivity (discussed) pair bonding / relationship closeness (discussed) sexual function and orgasm quality (discussed) social bonding discussion mood libido anxiety discussion mood / affiliative affect libido and intimacy anxiety / social-threat reactivity (discussed) pair bonding / relationship closeness (discussed) sexual function and orgasm quality (discussed) trust / social cognition research stress-hormone response in social contexts (research) chronic pain adjunct research (intranasal multi-day protocols) asd social outcomes research (mixed / large null trial) ptsd / trauma-related social comfort (compounding clinic talk) social bonding discussion mood / affiliative affect libido and intimacy anxiety / social-threat reactivity (discussed) pair bonding / relationship closeness (discussed) sexual function and orgasm quality (discussed) oxytocin is a natural hormone and peptide; nasal products are discussed for closeness and social comfort, separate from its obstetric use. oxytocin is a nasal peptide people look up for mood. subtle calm, openness, or slightly 'softer edges' \u2014 or nothing noticeable; hype-to-experience gap is a recurring forum theme. neuropeptides peptide mixed mixed \u2014 systemic hormone with context-dependent social effects. nasal social-use discussion is distinct from obstetric iv/im use. mixed local systemic", "legal_class": null }, { "id": 44, "slug": "dihexa", "name": "Dihexa", "aliases": [ "PNB-0408", "angiotensin IV analog discussion", "MM-201 (early lab designation in some histories)", "N-hexanoic-Tyr-Ile-(6)-aminohexanoic amide", "N-hexanoic-tyrosine-isoleucine-(6) aminohexanoic amide", "Dihexa peptide", "Dihexa oligopeptide", "Angiotensin IV analog (Dihexa)", "Nle1-Ang IV\u2013derived analog (Dihexa)", "HGF/c-Met potentiator (Dihexa discussions)", "ATH-1017 / fosgonimeton (related clinical candidate \u2014 not identical)" ], "type": "Non-peptide", "category": "Cognitive research compounds", "goals_use_cases": [ "cognition", "neuroplasticity discussion", "memory (research discussion)", "learning / study retention (anecdotal)", "focus / mental horsepower (discussed; not a stimulant frame)", "verbal fluency (self-report theme)", "brain fog / mental clarity (community)", "neurodegeneration research interest (Alzheimer-like models)", "synaptogenesis / spinogenesis narrative", "Parkinson\u2019s / motor-recovery research interest (preclinical grant-era talk)", "aged-cognition rescue narrative (rodent models)" ], "delivery_methods": [ "oral", "transdermal (discussed)" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "dihexa", "PNB-0408", "MM-201 (early lab designation in some histories)", "N-hexanoic-Tyr-Ile-(6)-aminohexanoic amide", "N-hexanoic-tyrosine-isoleucine-(6) aminohexanoic amide", "Dihexa peptide", "word finding", "brain fog", "DMSO", "dihexa acetate", "word-finding", "verbal fluency", "headache", "insomnia", "irritability" ], "feel_search": [ "word finding", "word-finding", "brain fog", "verbal fluency", "headache", "insomnia", "irritability" ], "summary": "Dihexa is a stabilized angiotensin-IV-derived research compound investigated for neuronal signaling and discussed as a nootropic.", "search_blob": "dihexa dihexa pnb-0408 angiotensin iv analog discussion mm-201 (early lab designation in some histories) n-hexanoic-tyr-ile-(6)-aminohexanoic amide n-hexanoic-tyrosine-isoleucine-(6) aminohexanoic amide dihexa peptide dihexa oligopeptide angiotensin iv analog (dihexa) nle1-ang iv\u2013derived analog (dihexa) hgf/c-met potentiator (dihexa discussions) ath-1017 / fosgonimeton (related clinical candidate \u2014 not identical) dihexa pnb-0408 mm-201 (early lab designation in some histories) n-hexanoic-tyr-ile-(6)-aminohexanoic amide n-hexanoic-tyrosine-isoleucine-(6) aminohexanoic amide dihexa peptide word finding brain fog dmso dihexa acetate word-finding verbal fluency headache insomnia irritability cognition neuroplasticity discussion memory (research discussion) learning / study retention (anecdotal) focus / mental horsepower (discussed; not a stimulant frame) verbal fluency (self-report theme) brain fog / mental clarity (community) neurodegeneration research interest (alzheimer-like models) synaptogenesis / spinogenesis narrative parkinson\u2019s / motor-recovery research interest (preclinical grant-era talk) aged-cognition rescue narrative (rodent models) word finding word-finding brain fog verbal fluency headache insomnia irritability dihexa is a stabilized angiotensin-iv-derived research compound investigated for neuronal signaling and discussed as a nootropic. one two-week user feels no obvious change but reports better chess results. occasional modafinil and eutropoflavin, practice effects and unstated route limit interpretation. dihexa is a peptide people look up for cognition. working memory under load, study retention, easier encoding over multi-week windows \u2014 gradual, not day-one stimulant lift. morning plus actual learning is the pairing. headache and \u201cprobably fake caps\u201d are loud. not a july 2026 pcac peptide. cognitive research compounds non-peptide systemic systemic brain-focused discussion\u2014oral or transdermal community products, not local muscle-site dosing; human exposure is unverified. systemic whole-body circulating", "legal_class": null }, { "id": 45, "slug": "n-acetyl-semax-amidate", "name": "N-Acetyl Semax Amidate", "aliases": [ "NASA", "NA-Semax Amidate", "Acetyl Semax Amidate", "NA Semax Amidate", "NA-Semax-Amidate", "N-Acetyl-Semax-Amidate", "N-Ac-Semax-NH2", "Ac-MEHFPGP-NH2 (sequence shorthand)", "Ac-Met-Glu-His-Phe-Pro-Gly-Pro-NH2", "N-Acetyl Semax (related single-cap analog \u2014 not identical)", "Semax Amidate (informal; incomplete name)" ], "type": "Peptide", "category": "Cognitive / nootropic peptides", "goals_use_cases": [ "cognition", "focus", "mood", "attention", "working memory (discussed)", "mental performance under stress", "mental stamina / deep-work endurance", "memory / learning support (discussed)", "neuroprotection discussion (inherited from parent Semax)", "nootropic stacking (especially with Selank-class)", "ADHD-adjacent focus talk (community only; not an approved indication)", "exam / sprint cognitive support" ], "delivery_methods": [ "nasal" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "n-acetyl-semax-amidate", "n acetyl semax amidate", "nacetylsemaxamidate", "N-Acetyl Semax Amidate", "NASA", "NA-Semax Amidate", "cognition", "focus", "attention", "working memory (discussed)", "mood", "mental performance under stress" ], "feel_search": [ "cognition", "focus", "attention", "working memory (discussed)", "mood", "mental performance under stress" ], "summary": "N-acetyl Semax amidate is a modified Semax peptide sold for focus and mental stamina; its claimed longer action is not well established.", "search_blob": "n-acetyl semax amidate n-acetyl-semax-amidate nasa na-semax amidate acetyl semax amidate na semax amidate na-semax-amidate n-acetyl-semax-amidate n-ac-semax-nh2 ac-mehfpgp-nh2 (sequence shorthand) ac-met-glu-his-phe-pro-gly-pro-nh2 n-acetyl semax (related single-cap analog \u2014 not identical) semax amidate (informal; incomplete name) n-acetyl-semax-amidate n acetyl semax amidate nacetylsemaxamidate n-acetyl semax amidate nasa na-semax amidate cognition focus attention working memory (discussed) mood mental performance under stress cognition focus mood attention working memory (discussed) mental performance under stress mental stamina / deep-work endurance memory / learning support (discussed) neuroprotection discussion (inherited from parent semax) nootropic stacking (especially with selank-class) adhd-adjacent focus talk (community only; not an approved indication) exam / sprint cognitive support cognition focus attention working memory (discussed) mood mental performance under stress n-acetyl semax amidate is a modified semax peptide sold for focus and mental stamina; its claimed longer action is not well established. reports range from alertness and easier attention to no effect, brain fog, anxiety or a later crash. other brain treatments, caffeine and p21 commonly cloud attribution. n-acetyl semax amidate is a peptide people look up for cognition. typical short \u201cexam or deep-work block\u201d checkpoint for real-task focus and mental stamina claims. cognitive / nootropic peptides peptide systemic brain-first research analog \u2014 intranasal discussion dominates; subq is a minority systemic route, and oral use is not established. systemic whole-body circulating", "legal_class": null }, { "id": 46, "slug": "n-acetyl-selank-amidate", "name": "N-Acetyl Selank Amidate", "aliases": [ "N-Acetyl Selank", "NA-Selank Amidate", "NA-Selank", "NA Selank Amidate", "Acetyl-Selank Amidate", "N-Acetyl-Selank-Amidate", "NA Selank", "Ac-Thr-Lys-Pro-Arg-Pro-Gly-Pro-NH2", "Ac-TKPRPGP-NH2 (sequence shorthand)", "N-Ac-Selank-NH2" ], "type": "Peptide", "category": "Cognitive / nootropic peptides", "goals_use_cases": [ "anxiety discussion", "mood", "cognition", "anxiety discussion (GAD / social / baseline edge)", "mood steadiness", "cognition under stress (secondary to anxiolysis)", "stress / high-demand work or exam windows", "calm focus without heavy sedation (discussed)", "anxiolytic without benzo-style fog/dependence narrative (borrowed from parent Selank)", "social / performance anxiety talk", "nootropic stacking (classic pair with NA-Semax Amidate)", "longer-lasting Selank analog search (stability marketing)", "\u201ccalm half\u201d of Semax/Selank dual stacks" ], "delivery_methods": [ "nasal" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "n-acetyl-selank-amidate", "n acetyl selank amidate", "nacetylselankamidate", "N-Acetyl Selank Amidate", "N-Acetyl Selank", "NA-Selank Amidate", "anxiety discussion (gad / social / baseline edge)", "mood steadiness", "cognition under stress (secondary to anxiolysis)", "stress / high-demand work or exam windows", "calm focus without heavy sedation (discussed)", "anxiolytic without benzo-style fog/dependence narrative (borrowed from parent selank)" ], "feel_search": [ "anxiety discussion (gad / social / baseline edge)", "mood steadiness", "cognition under stress (secondary to anxiolysis)", "stress / high-demand work or exam windows", "calm focus without heavy sedation (discussed)", "anxiolytic without benzo-style fog/dependence narrative (borrowed from parent selank)" ], "summary": "N-acetyl Selank amidate is a chemically modified Selank peptide sold for anxiety and calm focus; claims of longer action are uncertain.", "search_blob": "n-acetyl selank amidate n-acetyl-selank-amidate n-acetyl selank na-selank amidate na-selank na selank amidate acetyl-selank amidate n-acetyl-selank-amidate na selank ac-thr-lys-pro-arg-pro-gly-pro-nh2 ac-tkprpgp-nh2 (sequence shorthand) n-ac-selank-nh2 n-acetyl-selank-amidate n acetyl selank amidate nacetylselankamidate n-acetyl selank amidate n-acetyl selank na-selank amidate anxiety discussion (gad / social / baseline edge) mood steadiness cognition under stress (secondary to anxiolysis) stress / high-demand work or exam windows calm focus without heavy sedation (discussed) anxiolytic without benzo-style fog/dependence narrative (borrowed from parent selank) anxiety discussion mood cognition anxiety discussion (gad / social / baseline edge) mood steadiness cognition under stress (secondary to anxiolysis) stress / high-demand work or exam windows calm focus without heavy sedation (discussed) anxiolytic without benzo-style fog/dependence narrative (borrowed from parent selank) social / performance anxiety talk nootropic stacking (classic pair with na-semax amidate) longer-lasting selank analog search (stability marketing) \u201ccalm half\u201d of semax/selank dual stacks anxiety discussion (gad / social / baseline edge) mood steadiness cognition under stress (secondary to anxiolysis) stress / high-demand work or exam windows calm focus without heavy sedation (discussed) anxiolytic without benzo-style fog/dependence narrative (borrowed from parent selank) n-acetyl selank amidate is a chemically modified selank peptide sold for anxiety and calm focus; claims of longer action are uncertain. some describe calm or reduced rumination, while others notice little, head pressure or an odd detached feeling. product names often fail to confirm whether amidation is present. n-acetyl selank amidate is a peptide people look up for mood. multi-day stress steadiness and \u201cstill functional under load\u201d more than a single-dose buzz or euphoria. cognitive / nootropic peptides peptide systemic systemic cns framing \u2014 research-chem and community use is almost entirely intranasal for anxiolytic/nootropic goals, not local tissue repair. systemic whole-body circulating", "legal_class": null }, { "id": 47, "slug": "pinealon", "name": "Pinealon", "aliases": [ "EDR peptide", "pineal bioregulator", "EDR", "Glu-Asp-Arg", "Glu Asp Arg", "Pinealon peptide", "Khavinson EDR tripeptide", "Cortexin-associated EDR (research context)", "cytomed-class oral Pinealon (marketed bioregulator forms)" ], "type": "Peptide", "category": "Longevity & bioregulators", "goals_use_cases": [ "cognition", "sleep", "longevity", "cognition / memory & attention", "sleep quality & REM narratives", "circadian / pineal interest", "longevity / geroprotection talk", "neuroprotection (discussed)", "brain fog / mental performance (community)", "aging-brain support narratives", "post-stress or TBI-sequelae cognitive adjunct talk (historical clinical narratives)", "oxidative-stress / neuronal ROS reduction interest", "vs Epitalon dual-pineal stack searches" ], "delivery_methods": [ "subcutaneous", "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "pinealon", "EDR peptide", "EDR", "Glu-Asp-Arg", "Glu Asp Arg", "pineal bioregulator", "brain fog", "word finding", "verbal fluency", "emideltide (DSIP \u2014 not Pinealon)", "fog", "word-finding", "word recall", "rem sleep", "deep sleep", "slow wave", "garmin", "clarity", "morning crash", "groggy", "nothing" ], "feel_search": [ "brain fog", "fog", "word finding", "word-finding", "verbal fluency", "word recall", "rem sleep", "deep sleep", "slow wave", "garmin", "clarity", "morning crash", "groggy", "nothing" ], "summary": "Pinealon is the synthetic three-amino-acid peptide EDR, discussed as a brain-focused bioregulator for sleep and cognitive aging.", "search_blob": "pinealon pinealon edr peptide pineal bioregulator edr glu-asp-arg glu asp arg pinealon peptide khavinson edr tripeptide cortexin-associated edr (research context) cytomed-class oral pinealon (marketed bioregulator forms) pinealon edr peptide edr glu-asp-arg glu asp arg pineal bioregulator brain fog word finding verbal fluency emideltide (dsip \u2014 not pinealon) fog word-finding word recall rem sleep deep sleep slow wave garmin clarity morning crash groggy nothing cognition sleep longevity cognition / memory & attention sleep quality & rem narratives circadian / pineal interest longevity / geroprotection talk neuroprotection (discussed) brain fog / mental performance (community) aging-brain support narratives post-stress or tbi-sequelae cognitive adjunct talk (historical clinical narratives) oxidative-stress / neuronal ros reduction interest vs epitalon dual-pineal stack searches brain fog fog word finding word-finding verbal fluency word recall rem sleep deep sleep slow wave garmin clarity morning crash groggy nothing pinealon is the synthetic three-amino-acid peptide edr, discussed as a brain-focused bioregulator for sleep and cognitive aging. one intranasal user described daytime stimulation followed by sleepiness, while bedtime use brought vivid dreams; exercise and timing varied. pinealon is a peptide people look up for sleep. less \u201cheavy head,\u201d easier to stay on a thought \u2014 second-loudest story after sleep. people split hard: some wearables jump, a lot of people feel nothing. night is the usual sleep story. often stacked with epitalon, so credit gets messy. longevity & bioregulators peptide systemic systemic \u2014 cns/pineal-class bioregulator tripeptide discussed for brain, sleep, and gene-expression effects; not a local injury-site agent. systemic whole-body circulating", "legal_class": null }, { "id": 48, "slug": "thymosin-beta-4", "name": "Thymosin Beta-4", "aliases": [ "T\u03b24", "Timbetasin", "full-sequence TB4", "TB4", "TB-4", "Thymosin \u03b24", "Timbetasin (INN)", "full-length thymosin beta-4", "RGN-259 (0.1% ophthalmic research formulation)", "TMSB4X gene product (endogenous context)", "synthetic T\u03b24 (clinical IV / wound-gel programs)" ], "type": "Peptide", "category": "Healing & repair", "goals_use_cases": [ "recovery", "injury repair", "inflammation discussion", "soft-tissue healing", "wound healing (clinical + community)", "inflammation (discussed)", "joints & tendons", "mobility / flexibility", "muscle soft-tissue", "post-strain / overuse bounce-back", "dermal / ulcer repair (trial context)", "ocular surface research (dry eye, neurotrophic keratopathy)", "cardiac ischemia / cardioprotection research (preclinical + early clinical)", "skin/hair (minority discussion)", "performance continuity", "systemic repair narrative (full molecule vs fragment debate)" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Medium", "reach": "Mixed", "misspellings_search_terms": [ "thymosin-beta-4", "thymosin beta 4", "thymosinbeta4", "Thymosin Beta-4", "T\u03b24", "TB4", "recovery", "injury repair", "soft-tissue healing", "wound healing (clinical + community)", "inflammation (discussed)", "joints & tendons" ], "feel_search": [ "recovery", "injury repair", "soft-tissue healing", "wound healing (clinical + community)", "inflammation (discussed)", "joints & tendons" ], "summary": "Thymosin beta-4 is a natural 43-amino-acid peptide studied for tissue repair; the full-length peptide differs from shorter TB-500 fragments.", "search_blob": "thymosin beta-4 thymosin-beta-4 t\u03b24 timbetasin full-sequence tb4 tb4 tb-4 thymosin \u03b24 timbetasin (inn) full-length thymosin beta-4 rgn-259 (0.1% ophthalmic research formulation) tmsb4x gene product (endogenous context) synthetic t\u03b24 (clinical iv / wound-gel programs) thymosin-beta-4 thymosin beta 4 thymosinbeta4 thymosin beta-4 t\u03b24 tb4 recovery injury repair soft-tissue healing wound healing (clinical + community) inflammation (discussed) joints & tendons recovery injury repair inflammation discussion soft-tissue healing wound healing (clinical + community) inflammation (discussed) joints & tendons mobility / flexibility muscle soft-tissue post-strain / overuse bounce-back dermal / ulcer repair (trial context) ocular surface research (dry eye, neurotrophic keratopathy) cardiac ischemia / cardioprotection research (preclinical + early clinical) skin/hair (minority discussion) performance continuity systemic repair narrative (full molecule vs fragment debate) recovery injury repair soft-tissue healing wound healing (clinical + community) inflammation (discussed) joints & tendons thymosin beta-4 is a natural 43-amino-acid peptide studied for tissue repair; the full-length peptide differs from shorter tb-500 fragments. one combined bpc/tb4 user reported an improved elbow but still needed a shoulder cortisone injection; the product's identity was disputed. thymosin beta-4 is a peptide people look up for recovery. people report multi-week faster bounce-back from strains, overuse stiffness, and training niggles. healing & repair peptide mixed mixed \u2014 research-chem injectables are treated as systemic soft-tissue repair; clinical programs also use topical wound gels and ophthalmic drops. mixed local systemic", "legal_class": null }, { "id": 49, "slug": "follistatin-344", "name": "Follistatin 344", "aliases": [ "FST-344", "FS-344", "Follistatin", "gray FS-344", "FS344", "FST344", "Follistatin-344", "FST-344 (precursor \u2192 FS-315)", "FS344 / FS315 isoform family", "AAV1-FS344 (gene-therapy context)", "recombinant follistatin (research peptide)" ], "type": "Peptide", "category": "Growth factors", "goals_use_cases": [ "muscle growth", "myostatin discussion", "performance", "muscle growth / hypertrophy (discussed)", "myostatin inhibition pathway interest", "performance / strength (discussed)", "lean mass / body recomposition (discussed)", "recovery (secondary discussion)", "site / regional muscle emphasis (IM talk)", "gene therapy research interest (BMD / sIBM / longevity clinics)", "sarcopenia / age-related muscle loss framing (longevity discourse)", "vs other myostatin-class agents (ACE-031, YK-11, antibodies)" ], "delivery_methods": [ "gene therapy discussion", "research peptide injection discussion" ], "discussion_popularity": "Medium", "reach": "Mixed", "misspellings_search_terms": [ "follistatin-344", "follistatin 344", "follistatin344", "FST-344", "FS-344", "FS344", "fst 344 pip", "follistatin iron den", "flgr vs fst-344", "muscle growth / hypertrophy (discussed)", "myostatin inhibition pathway interest", "performance / strength (discussed)", "lean mass / body recomposition (discussed)", "recovery (secondary discussion)", "site / regional muscle emphasis (im talk)", "pip only", "iron den follistatin", "flgr mixup", "100 dollars a vial" ], "feel_search": [ "muscle growth / hypertrophy (discussed)", "myostatin inhibition pathway interest", "performance / strength (discussed)", "lean mass / body recomposition (discussed)", "recovery (secondary discussion)", "site / regional muscle emphasis (im talk)", "pip only", "iron den follistatin", "flgr mixup", "100 dollars a vial" ], "summary": "Follistatin-344 is a precursor protein discussed for muscle growth through myostatin binding; gene therapy and injectable-protein products are different interventions.", "search_blob": "follistatin 344 follistatin-344 fst-344 fs-344 follistatin gray fs-344 fs344 fst344 follistatin-344 fst-344 (precursor \u2192 fs-315) fs344 / fs315 isoform family aav1-fs344 (gene-therapy context) recombinant follistatin (research peptide) follistatin-344 follistatin 344 follistatin344 fst-344 fs-344 fs344 fst 344 pip follistatin iron den flgr vs fst-344 muscle growth / hypertrophy (discussed) myostatin inhibition pathway interest performance / strength (discussed) lean mass / body recomposition (discussed) recovery (secondary discussion) site / regional muscle emphasis (im talk) pip only iron den follistatin flgr mixup 100 dollars a vial muscle growth myostatin discussion performance muscle growth / hypertrophy (discussed) myostatin inhibition pathway interest performance / strength (discussed) lean mass / body recomposition (discussed) recovery (secondary discussion) site / regional muscle emphasis (im talk) gene therapy research interest (bmd / sibm / longevity clinics) sarcopenia / age-related muscle loss framing (longevity discourse) vs other myostatin-class agents (ace-031, yk-11, antibodies) muscle growth / hypertrophy (discussed) myostatin inhibition pathway interest performance / strength (discussed) lean mass / body recomposition (discussed) recovery (secondary discussion) site / regional muscle emphasis (im talk) pip only iron den follistatin flgr mixup 100 dollars a vial follistatin-344 is a precursor protein discussed for muscle growth through myostatin binding; gene therapy and injectable-protein products are different interventions. a forum user claims retained strength gains, while others question product identity and evidence. these brief accounts do not establish muscle growth from a verified protein product. follistatin 344 is a peptide people look up for muscle. some users report overload capacity, pump, and trained-muscle soreness. do not copy flgr milligrams or jay\u2019s 20-day 100 mcg quarterly chart onto a 1 mg research vial. aav gene delivery is a different product class. growth factors peptide mixed mixed and contested. mixed local systemic", "legal_class": null }, { "id": 50, "slug": "mgf", "name": "MGF (Mechano Growth Factor)", "aliases": [ "IGF-1 Ec", "non-PEGylated MGF", "Mechano Growth Factor", "Mechano-Growth Factor", "IGF-1Ec", "IGF-IEc", "IGF-1 Eb (rodent nomenclature confusion)", "MGF-E", "MGF E-peptide", "MGF-Ct24E", "MGF-24aa-E", "native MGF", "unmodified MGF", "IGF-1Ec E-domain peptide" ], "type": "Peptide", "category": "Growth factors", "goals_use_cases": [ "muscle growth", "recovery", "muscle growth / hypertrophy (discussed)", "recovery / post-workout repair talk", "satellite-cell activation / progenitor-pool lore", "localized / site-specific muscle repair discussion", "hypertrophy adjunct on progressive-overload blocks", "injury-adjacent soft-tissue / muscle-strain downtime talk", "performance / training continuity", "age-related anabolic-resistance / sarcopenia discussion (research framing)", "stack partner with IGF-1 LR3 (\u201cproliferation then differentiation\u201d lore)" ], "delivery_methods": [ "intramuscular" ], "discussion_popularity": "Medium", "reach": "Local", "misspellings_search_terms": [ "mgf", "MGF (Mechano Growth Factor)", "mgf-(mechano-growth-factor)", "Mechano Growth Factor", "Mechano-Growth Factor", "IGF-1 Ec", "muscle growth / hypertrophy (discussed)", "recovery / post-workout repair talk", "satellite-cell activation / progenitor-pool lore", "localized / site-specific muscle repair discussion", "hypertrophy adjunct on progressive-overload blocks", "injury-adjacent soft-tissue / muscle-strain downtime talk" ], "feel_search": [ "muscle growth / hypertrophy (discussed)", "recovery / post-workout repair talk", "satellite-cell activation / progenitor-pool lore", "localized / site-specific muscle repair discussion", "hypertrophy adjunct on progressive-overload blocks", "injury-adjacent soft-tissue / muscle-strain downtime talk" ], "summary": "MGF covers IGF-1Ec research and synthetic E-domain peptides sold for muscle recovery; a vial is not the same thing as the body's IGF-1Ec.", "search_blob": "mgf (mechano growth factor) mgf igf-1 ec non-pegylated mgf mechano growth factor mechano-growth factor igf-1ec igf-iec igf-1 eb (rodent nomenclature confusion) mgf-e mgf e-peptide mgf-ct24e mgf-24aa-e native mgf unmodified mgf igf-1ec e-domain peptide mgf mgf (mechano growth factor) mgf-(mechano-growth-factor) mechano growth factor mechano-growth factor igf-1 ec muscle growth / hypertrophy (discussed) recovery / post-workout repair talk satellite-cell activation / progenitor-pool lore localized / site-specific muscle repair discussion hypertrophy adjunct on progressive-overload blocks injury-adjacent soft-tissue / muscle-strain downtime talk muscle growth recovery muscle growth / hypertrophy (discussed) recovery / post-workout repair talk satellite-cell activation / progenitor-pool lore localized / site-specific muscle repair discussion hypertrophy adjunct on progressive-overload blocks injury-adjacent soft-tissue / muscle-strain downtime talk performance / training continuity age-related anabolic-resistance / sarcopenia discussion (research framing) stack partner with igf-1 lr3 (\u201cproliferation then differentiation\u201d lore) muscle growth / hypertrophy (discussed) recovery / post-workout repair talk satellite-cell activation / progenitor-pool lore localized / site-specific muscle repair discussion hypertrophy adjunct on progressive-overload blocks injury-adjacent soft-tissue / muscle-strain downtime talk mgf covers igf-1ec research and synthetic e-domain peptides sold for muscle recovery; a vial is not the same thing as the body's igf-1ec. people report anything from less local soreness to no benefit. injection-site sting or fullness can be noticeable; longer-term muscle gains are hard to separate from training. mgf (mechano growth factor) is a peptide people look up for muscle. gradual fullness or measurements over multi-week progressive-overload blocks; single-agent credit is unreliable. growth factors peptide local local \u2014 people pin it in or near just-trained muscle. local site pin topical", "legal_class": null }, { "id": 51, "slug": "ara-290", "name": "ARA-290", "aliases": [ "Cibinetide", "pyroglutamate helix B surface peptide", "pHBSP", "PHBSP", "Pyroglutamate HBSP", "ARA 290", "ARA290", "Helix B surface peptide", "pGlu-Glu-Gln-Leu-Glu-Arg-Ala-Leu-Asn-Ser-Ser" ], "type": "Peptide", "category": "Healing & repair", "goals_use_cases": [ "neuropathy discussion", "inflammation discussion", "recovery", "small fiber neuropathy (SFN)", "sarcoidosis-associated neuropathic pain", "diabetic peripheral neuropathy discussion", "neuropathic pain (burning, tingling, allodynia)", "corneal / small-nerve fiber repair narrative", "inflammation / tissue-protection discussion", "metabolic adjacency (HbA1c / lipids in T2D trial)", "recovery and nerve-support stacks (community)", "disease-modification hope vs symptom-only relief debate" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "ara-290", "ara 290", "ara290", "Cibinetide", "pHBSP", "pyroglutamate helix B surface peptide", "small fiber neuropathy (sfn)", "sarcoidosis-associated neuropathic pain", "diabetic peripheral neuropathy discussion", "neuropathic pain (burning, tingling, allodynia)", "corneal / small-nerve fiber repair narrative", "inflammation / tissue-protection discussion" ], "feel_search": [ "small fiber neuropathy (sfn)", "sarcoidosis-associated neuropathic pain", "diabetic peripheral neuropathy discussion", "neuropathic pain (burning, tingling, allodynia)", "corneal / small-nerve fiber repair narrative", "inflammation / tissue-protection discussion" ], "summary": "ARA-290 (cibinetide) is an erythropoietin-derived research peptide studied for small-fiber nerve pain without the intended blood-building action.", "search_blob": "ara-290 ara-290 cibinetide pyroglutamate helix b surface peptide phbsp phbsp pyroglutamate hbsp ara 290 ara290 helix b surface peptide pglu-glu-gln-leu-glu-arg-ala-leu-asn-ser-ser ara-290 ara 290 ara290 cibinetide phbsp pyroglutamate helix b surface peptide small fiber neuropathy (sfn) sarcoidosis-associated neuropathic pain diabetic peripheral neuropathy discussion neuropathic pain (burning, tingling, allodynia) corneal / small-nerve fiber repair narrative inflammation / tissue-protection discussion neuropathy discussion inflammation discussion recovery small fiber neuropathy (sfn) sarcoidosis-associated neuropathic pain diabetic peripheral neuropathy discussion neuropathic pain (burning, tingling, allodynia) corneal / small-nerve fiber repair narrative inflammation / tissue-protection discussion metabolic adjacency (hba1c / lipids in t2d trial) recovery and nerve-support stacks (community) disease-modification hope vs symptom-only relief debate small fiber neuropathy (sfn) sarcoidosis-associated neuropathic pain diabetic peripheral neuropathy discussion neuropathic pain (burning, tingling, allodynia) corneal / small-nerve fiber repair narrative inflammation / tissue-protection discussion ara-290 (cibinetide) is an erythropoietin-derived research peptide studied for small-fiber nerve pain without the intended blood-building action. one neuropathy writer reports relief around day 12, but later says it stopped helping after about seven months. that follow-up tempers the early positive log. ara-290 is a peptide people look up for inflammation. occasional credit for better sleep or more usable days from lower night pain \u2014 not framed as sedation. healing & repair peptide systemic systemic \u2014 sc or iv for innate-repair / neuropathic and inflammatory pathways; not a local joint depot or topical. systemic whole-body circulating", "legal_class": null }, { "id": 52, "slug": "vip", "name": "VIP", "aliases": [ "Vasoactive Intestinal Peptide", "Vasoactive Intestinal Polypeptide", "Aviptadil (pharmaceutical synthetic VIP)", "VIP nasal spray", "Intranasal VIP", "VIP-CIRS / Shoemaker VIP", "Invicorp component (aviptadil + phentolamine ED product \u2014 different use/route)" ], "type": "Peptide", "category": "Immune & neuropeptides", "goals_use_cases": [ "immune", "mold illness discussion", "inflammation discussion", "immune modulation (discussed)", "mold illness / biotoxin discussion", "CIRS / water-damaged building (WDB) protocol step (discussed)", "inflammation / innate immune calm (discussed)", "neuroimmune regulation (discussed)", "grey-matter / NeuroQuant recovery narratives (CIRS literature)", "pulmonary vascular / exercise PASP discussion", "low endogenous VIP / MSH biomarker framing", "post-exposure recovery narratives", "sleep / circadian adjacency in CIRS clusters", "pulmonary hypertension and ARDS research (Aviptadil \u2014 separate from CIRS nasal culture)", "erectile-dysfunction pharmaceutical adjacency (Invicorp aviptadil dose \u2014 not CIRS stack)" ], "delivery_methods": [ "nasal", "subcutaneous" ], "discussion_popularity": "Medium", "reach": "Mixed", "misspellings_search_terms": [ "vip", "Vasoactive Intestinal Peptide", "Vasoactive Intestinal Polypeptide", "Aviptadil (pharmaceutical synthetic VIP)", "VIP nasal spray", "Intranasal VIP", "immune modulation (discussed)", "mold illness / biotoxin discussion", "cirs / water-damaged building (wdb) protocol step (discussed)", "inflammation / innate immune calm (discussed)", "neuroimmune regulation (discussed)", "grey-matter / neuroquant recovery narratives (cirs literature)" ], "feel_search": [ "immune modulation (discussed)", "mold illness / biotoxin discussion", "cirs / water-damaged building (wdb) protocol step (discussed)", "inflammation / innate immune calm (discussed)", "neuroimmune regulation (discussed)", "grey-matter / neuroquant recovery narratives (cirs literature)" ], "summary": "VIP is vasoactive intestinal peptide, a natural 28-amino-acid signaling peptide; synthetic aviptadil is discussed in CIRS and other clinical contexts.", "search_blob": "vip vip vasoactive intestinal peptide vasoactive intestinal polypeptide aviptadil (pharmaceutical synthetic vip) vip nasal spray intranasal vip vip-cirs / shoemaker vip invicorp component (aviptadil + phentolamine ed product \u2014 different use/route) vip vasoactive intestinal peptide vasoactive intestinal polypeptide aviptadil (pharmaceutical synthetic vip) vip nasal spray intranasal vip immune modulation (discussed) mold illness / biotoxin discussion cirs / water-damaged building (wdb) protocol step (discussed) inflammation / innate immune calm (discussed) neuroimmune regulation (discussed) grey-matter / neuroquant recovery narratives (cirs literature) immune mold illness discussion inflammation discussion immune modulation (discussed) mold illness / biotoxin discussion cirs / water-damaged building (wdb) protocol step (discussed) inflammation / innate immune calm (discussed) neuroimmune regulation (discussed) grey-matter / neuroquant recovery narratives (cirs literature) pulmonary vascular / exercise pasp discussion low endogenous vip / msh biomarker framing post-exposure recovery narratives sleep / circadian adjacency in cirs clusters pulmonary hypertension and ards research (aviptadil \u2014 separate from cirs nasal culture) erectile-dysfunction pharmaceutical adjacency (invicorp aviptadil dose \u2014 not cirs stack) immune modulation (discussed) mold illness / biotoxin discussion cirs / water-damaged building (wdb) protocol step (discussed) inflammation / innate immune calm (discussed) neuroimmune regulation (discussed) grey-matter / neuroquant recovery narratives (cirs literature) vip is vasoactive intestinal peptide, a natural 28-amino-acid signaling peptide; synthetic aviptadil is discussed in cirs and other clinical contexts. some nasal-spray users describe better concentration; others initially report more anxiety, bloating, pain or feeling generally unwell. vip is a peptide people look up for immune support. symptoms reduced toward control levels with reported quality-of-life gains in all trial patients. immune & neuropeptides peptide mixed mixed \u2014 nasal cirs use, systemic subq discussion, and inhaled or iv pharmaceutical research are distinct contexts. mixed local systemic", "legal_class": null }, { "id": 53, "slug": "larazotide", "name": "Larazotide", "aliases": [ "AT-1001", "Larazotide acetate", "AT1001", "AT 1001", "INN-202", "GGVLVQPG", "H-Gly-Gly-Val-Leu-Val-Gln-Pro-Gly-OH", "zonulin antagonist (discussion shorthand)", "tight-junction regulator peptide (discussion)" ], "type": "Peptide", "category": "Gut & inflammation peptides", "goals_use_cases": [ "recovery", "gut health", "tight junction discussion", "celiac adjacency discussion", "gut health / barrier integrity (discussed)", "tight junction / zonulin-pathway discussion", "celiac disease symptom adjacency (trial + community)", "intestinal permeability / \u201cleaky gut\u201d talk", "nonresponsive celiac on gluten-free diet (trial design)", "GI symptom support (bloating, pain, cramping domains \u2014 discussed)", "gluten-challenge protection talk (trial context)", "autoimmune adjacency (speculative community)", "post-viral / MIS-C / long-COVID gut-leak hypotheses (early clinical interest)", "stack partner with BPC-157 / KPV for multi-mechanism gut protocols" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Mixed", "misspellings_search_terms": [ "larazotide", "Larazotide acetate", "AT-1001", "AT1001", "AT 1001", "INN-202", "leaky gut", "tight junction", "bloating", "gluten", "gut trifecta", "before meals", "not a pin", "zonulin" ], "feel_search": [ "leaky gut", "tight junction", "bloating", "gluten", "gut trifecta", "before meals", "not a pin", "zonulin" ], "summary": "Larazotide acetate is an experimental oral peptide intended to regulate the gut barrier, studied in celiac disease and discussed for persistent gut symptoms.", "search_blob": "larazotide larazotide at-1001 larazotide acetate at1001 at 1001 inn-202 ggvlvqpg h-gly-gly-val-leu-val-gln-pro-gly-oh zonulin antagonist (discussion shorthand) tight-junction regulator peptide (discussion) larazotide larazotide acetate at-1001 at1001 at 1001 inn-202 leaky gut tight junction bloating gluten gut trifecta before meals not a pin zonulin recovery gut health tight junction discussion celiac adjacency discussion gut health / barrier integrity (discussed) tight junction / zonulin-pathway discussion celiac disease symptom adjacency (trial + community) intestinal permeability / \u201cleaky gut\u201d talk nonresponsive celiac on gluten-free diet (trial design) gi symptom support (bloating, pain, cramping domains \u2014 discussed) gluten-challenge protection talk (trial context) autoimmune adjacency (speculative community) post-viral / mis-c / long-covid gut-leak hypotheses (early clinical interest) stack partner with bpc-157 / kpv for multi-mechanism gut protocols leaky gut tight junction bloating gluten gut trifecta before meals not a pin zonulin larazotide acetate is an experimental oral peptide intended to regulate the gut barrier, studied in celiac disease and discussed for persistent gut symptoms. usually there is no stimulant-like sensation. some report less bloating or discomfort, while others notice little; one positive account later became hard to interpret after illness and treatment changes. larazotide is an oral peptide people look up for gut comfort. people report quieter bloating or less post-exposure anxiety. 0.5 mg three times a day before meals is the trial winner. higher was not better. not a pin. not an approved celiac drug. gut & inflammation peptides peptide mixed gut-local oral \u2014 people swallow it before meals for the lining, not a scalp or joint pin. vendor shot charts exist and are not the trial path. mixed local systemic", "legal_class": null }, { "id": 54, "slug": "humanin", "name": "Humanin", "aliases": [ "HN", "mitochondrial-derived peptide humanin", "MDP humanin", "MT-RNR2 peptide", "MTRNR2-encoded peptide", "HNG (S14G-humanin analog)", "S14G-HN", "S14G-humanin", "Humanin-G", "HNGF6A", "Colivelin (related potent derivative)", "MAPRGFSCLLLLTSEIDLPVKRRA" ], "type": "Peptide", "category": "Mitochondrial & metabolic peptides", "goals_use_cases": [ "longevity", "neuroprotection discussion", "metabolic health", "longevity / healthspan", "Alzheimer\u2019s / cognitive aging research interest", "insulin sensitivity (discussed)", "mitochondrial function / cytoprotection", "cardiovascular / ischemia research interest", "beta-cell survival / diabetes models", "anti-apoptotic cell-stress resilience", "healthy aging biomarker interest", "exercise\u2013mito peptide discussion" ], "delivery_methods": [ "subcutaneous", "nasal" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "humanin", "HN", "mitochondrial-derived peptide humanin", "MDP humanin", "MT-RNR2 peptide", "MTRNR2-encoded peptide", "longevity / healthspan", "neuroprotection discussion", "alzheimer\u2019s / cognitive aging research interest", "metabolic health", "insulin sensitivity (discussed)", "mitochondrial function / cytoprotection" ], "feel_search": [ "longevity / healthspan", "neuroprotection discussion", "alzheimer\u2019s / cognitive aging research interest", "metabolic health", "insulin sensitivity (discussed)", "mitochondrial function / cytoprotection" ], "summary": "Humanin is a mitochondrial-derived peptide studied for cellular stress protection; biohacker discussion focuses on aging, cognition and metabolic health.", "search_blob": "humanin humanin hn mitochondrial-derived peptide humanin mdp humanin mt-rnr2 peptide mtrnr2-encoded peptide hng (s14g-humanin analog) s14g-hn s14g-humanin humanin-g hngf6a colivelin (related potent derivative) maprgfsclllltseidlpvkrra humanin hn mitochondrial-derived peptide humanin mdp humanin mt-rnr2 peptide mtrnr2-encoded peptide longevity / healthspan neuroprotection discussion alzheimer\u2019s / cognitive aging research interest metabolic health insulin sensitivity (discussed) mitochondrial function / cytoprotection longevity neuroprotection discussion metabolic health longevity / healthspan alzheimer\u2019s / cognitive aging research interest insulin sensitivity (discussed) mitochondrial function / cytoprotection cardiovascular / ischemia research interest beta-cell survival / diabetes models anti-apoptotic cell-stress resilience healthy aging biomarker interest exercise\u2013mito peptide discussion longevity / healthspan neuroprotection discussion alzheimer\u2019s / cognitive aging research interest metabolic health insulin sensitivity (discussed) mitochondrial function / cytoprotection humanin is a mitochondrial-derived peptide studied for cellular stress protection; biohacker discussion focuses on aging, cognition and metabolic health. humanin is a peptide people look up for longevity. possible sleep or anxiety changes and null effects, not a consistent energy or clarity pattern. mitochondrial & metabolic peptides peptide systemic systemic \u2014 circulating mitochondrial-derived signal with multi-organ research interest (brain, heart, pancreas/islets, endothelium, skeletal muscle, retina). systemic whole-body circulating", "legal_class": null }, { "id": 55, "slug": "foxo4-dri", "name": "FOXO4-DRI", "aliases": [ "FOXO4 D-Retro-Inverso", "proxofim (colloquial discussion)", "FOXO4 DRI", "FOX04-DRI", "FOXO4DRI", "Proxofim (vendor/colloquial discussion)", "FOXO4 interference peptide (DRI)", "FOXO4 D-retro-inverso peptide", "FOXO4-p53 interference peptide" ], "type": "Peptide", "category": "Senolytic research peptides", "goals_use_cases": [ "longevity", "senolytic discussion", "longevity / healthspan (discussed)", "senolytic / \u201czombie cell\u201d clearance discussion", "cellular senescence research", "inflammation / SASP reduction narratives", "chemotherapy-recovery models (preclinical)", "age-related testosterone / Leydig cell discussion (preclinical)", "cartilage / chondrocyte senescence research (in vitro human cells)", "endothelial / vascular aging research interest", "tissue homeostasis and fitness restoration (aged-mouse framing)", "hair/fur density lore from mouse coat recovery", "complement to small-molecule senolytics (D+Q, fisetin) in stack talk" ], "delivery_methods": [ "research injection discussion" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "foxo4-dri", "foxo4 dri", "foxo4dri", "FOXO4 D-Retro-Inverso", "FOX04-DRI", "Proxofim (vendor/colloquial discussion)", "longevity / healthspan (discussed)", "senolytic / \u201czombie cell\u201d clearance discussion", "cellular senescence research", "inflammation / sasp reduction narratives", "chemotherapy-recovery models (preclinical)", "age-related testosterone / leydig cell discussion (preclinical)" ], "feel_search": [ "longevity / healthspan (discussed)", "senolytic / \u201czombie cell\u201d clearance discussion", "cellular senescence research", "inflammation / sasp reduction narratives", "chemotherapy-recovery models (preclinical)", "age-related testosterone / leydig cell discussion (preclinical)" ], "summary": "FOXO4-DRI is an experimental peptide designed to kill senescent cells; longevity users discuss short self-experiments, with uncertain human benefit.", "search_blob": "foxo4-dri foxo4-dri foxo4 d-retro-inverso proxofim (colloquial discussion) foxo4 dri fox04-dri foxo4dri proxofim (vendor/colloquial discussion) foxo4 interference peptide (dri) foxo4 d-retro-inverso peptide foxo4-p53 interference peptide foxo4-dri foxo4 dri foxo4dri foxo4 d-retro-inverso fox04-dri proxofim (vendor/colloquial discussion) longevity / healthspan (discussed) senolytic / \u201czombie cell\u201d clearance discussion cellular senescence research inflammation / sasp reduction narratives chemotherapy-recovery models (preclinical) age-related testosterone / leydig cell discussion (preclinical) longevity senolytic discussion longevity / healthspan (discussed) senolytic / \u201czombie cell\u201d clearance discussion cellular senescence research inflammation / sasp reduction narratives chemotherapy-recovery models (preclinical) age-related testosterone / leydig cell discussion (preclinical) cartilage / chondrocyte senescence research (in vitro human cells) endothelial / vascular aging research interest tissue homeostasis and fitness restoration (aged-mouse framing) hair/fur density lore from mouse coat recovery complement to small-molecule senolytics (d+q, fisetin) in stack talk longevity / healthspan (discussed) senolytic / \u201czombie cell\u201d clearance discussion cellular senescence research inflammation / sasp reduction narratives chemotherapy-recovery models (preclinical) age-related testosterone / leydig cell discussion (preclinical) foxo4-dri is an experimental peptide designed to kill senescent cells; longevity users discuss short self-experiments, with uncertain human benefit. foxo4-dri is a peptide people look up for longevity. many short runs report nothing noticeable; product identity/purity is a huge confounder on expensive d-synthesis material. \u201cproxofim\u201d appears on some research-vendor listings for the same senolytic peptide concept \u2014 not a distinct clinical brand. senolytic research peptides peptide systemic systemic \u2014 designed to disrupt foxo4\u2013p53 survival signaling in senescent cells body-wide after parenteral exposure, not a local injury-site or cosmetic peptide. systemic whole-body circulating", "legal_class": null }, { "id": 56, "slug": "p21", "name": "P21", "aliases": [ "P021", "peptide 021 discussion", "Peptide 021", "Peptide 21", "P21 peptide", "P021 peptide", "CNTF-derived peptide P21", "CNTF small-molecule peptide mimetic P021", "Ac-DGGLAG-NH2 (adamantylated form)", "Ac-DGGL A G-NH2", "GLXC-21260 (catalog-style ID in some listings)", "CAS 1246751-68-7 (common registry listing)" ], "type": "Peptide", "category": "Cognitive / nootropic peptides", "goals_use_cases": [ "cognition", "neurogenesis discussion", "memory / learning (discussed)", "synaptic plasticity (preclinical)", "neuroprotection (preclinical)", "age-related cognitive interest", "Alzheimer\u2019s model research interest", "tau / amyloid pathology interest (animal AD models)", "Down syndrome model research interest (preclinical)", "brain fog / clarity without stimulant frame (community)", "structural rebuild vs acute focus (community typology)" ], "delivery_methods": [ "nasal", "subcutaneous" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "p21", "P021", "Peptide 021", "Peptide 21", "P21 peptide", "P021 peptide", "cognition", "neurogenesis discussion", "memory / learning (discussed)", "synaptic plasticity (preclinical)", "neuroprotection (preclinical)", "age-related cognitive interest" ], "feel_search": [ "cognition", "neurogenesis discussion", "memory / learning (discussed)", "synaptic plasticity (preclinical)", "neuroprotection (preclinical)", "age-related cognitive interest" ], "summary": "P21/P021 is an experimental CNTF-derived peptide mimetic discussed for memory and mental clarity; it is not the cell-cycle protein p21.", "search_blob": "p21 p21 p021 peptide 021 discussion peptide 021 peptide 21 p21 peptide p021 peptide cntf-derived peptide p21 cntf small-molecule peptide mimetic p021 ac-dgglag-nh2 (adamantylated form) ac-dggl a g-nh2 glxc-21260 (catalog-style id in some listings) cas 1246751-68-7 (common registry listing) p21 p021 peptide 021 peptide 21 p21 peptide p021 peptide cognition neurogenesis discussion memory / learning (discussed) synaptic plasticity (preclinical) neuroprotection (preclinical) age-related cognitive interest cognition neurogenesis discussion memory / learning (discussed) synaptic plasticity (preclinical) neuroprotection (preclinical) age-related cognitive interest alzheimer\u2019s model research interest tau / amyloid pathology interest (animal ad models) down syndrome model research interest (preclinical) brain fog / clarity without stimulant frame (community) structural rebuild vs acute focus (community typology) cognition neurogenesis discussion memory / learning (discussed) synaptic plasticity (preclinical) neuroprotection (preclinical) age-related cognitive interest p21/p021 is an experimental cntf-derived peptide mimetic discussed for memory and mental clarity; it is not the cell-cycle protein p21. some nasal users describe clearer thinking or calmer mood over weeks, while others notice little or fading benefit. an acute injection account described panic, so routes should not be pooled. p21 is a peptide, not the p21 cell-cycle protein, people look up for memory. subset report clearer thinking without jitter/crash; others report null or only dream/mood changes. marketed as a \u201cstructural\u201d neurogenic nootropic from rodent dentate-gyrus, bdnf and synaptic-marker work; this does not establish human neurogenesis or exclude day-one effects. cognitive / nootropic peptides peptide systemic brain-focused research peptide \u2014 nasal, subq and oral reports do not establish targeted human brain delivery. systemic whole-body circulating", "legal_class": null }, { "id": 57, "slug": "cerebrolysin", "name": "Cerebrolysin", "aliases": [ "neuropeptide mixture", "FPF 1070", "FPF-1070", "FPF1070", "Cerebrolysin concentrate", "neuropeptide mixture (porcine)", "brain protein hydrolysate (Cerebrolysin)", "porcine brain-derived peptide preparation", "EVER Pharma Cerebrolysin", "Cerebrolysin\u00ae", "cerebroprotein hydrolysate (related class \u2014 not identical to branded Cerebrolysin)", "Renacenz (related cerebroprotein product discussions)" ], "type": "Peptide", "category": "Cognitive / nootropic peptides", "goals_use_cases": [ "cognition", "recovery", "neuroprotection discussion", "post-stroke discussion", "TBI recovery discussion", "dementia research interest", "vascular dementia discussion", "Alzheimer\u2019s / AD-type dementia discussion", "memory & learning (discussed)", "neuroplasticity discussion", "brain fog (anecdotal)", "mental clarity / deep work (community)", "performance continuity (cognitive)", "post-concussion / mild TBI community interest", "aging-brain repair narrative" ], "delivery_methods": [ "intramuscular", "IV" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "cerebrolysin", "FPF 1070", "FPF-1070", "FPF1070", "Cerebrolysin concentrate", "neuropeptide mixture (porcine)", "cognition", "neuroprotection discussion", "recovery", "post-stroke discussion", "tbi recovery discussion", "dementia research interest" ], "feel_search": [ "cognition", "neuroprotection discussion", "recovery", "post-stroke discussion", "tbi recovery discussion", "dementia research interest" ], "summary": "Cerebrolysin is an injectable mixture of peptides and amino acids used in some countries for neurological care and discussed by biohackers for cognition.", "search_blob": "cerebrolysin cerebrolysin neuropeptide mixture fpf 1070 fpf-1070 fpf1070 cerebrolysin concentrate neuropeptide mixture (porcine) brain protein hydrolysate (cerebrolysin) porcine brain-derived peptide preparation ever pharma cerebrolysin cerebrolysin\u00ae cerebroprotein hydrolysate (related class \u2014 not identical to branded cerebrolysin) renacenz (related cerebroprotein product discussions) cerebrolysin fpf 1070 fpf-1070 fpf1070 cerebrolysin concentrate neuropeptide mixture (porcine) cognition neuroprotection discussion recovery post-stroke discussion tbi recovery discussion dementia research interest cognition recovery neuroprotection discussion post-stroke discussion tbi recovery discussion dementia research interest vascular dementia discussion alzheimer\u2019s / ad-type dementia discussion memory & learning (discussed) neuroplasticity discussion brain fog (anecdotal) mental clarity / deep work (community) performance continuity (cognitive) post-concussion / mild tbi community interest aging-brain repair narrative cognition neuroprotection discussion recovery post-stroke discussion tbi recovery discussion dementia research interest cerebrolysin is an injectable mixture of peptides and amino acids used in some countries for neurological care and discussed by biohackers for cognition. a 20-day course log describes early well-being and vivid dreams, followed by fading euphoria and increasing brain fog. exercise and other supplements also changed. cerebrolysin is an injected peptide people look up for cognition. subtle clarity for some, nothing for others; tolerance check for agitation/heat/sleep. cognitive / nootropic peptides peptide systemic an im/iv porcine-brain peptide mixture with systemic exposure; not one receptor-specific peptide. systemic whole-body circulating", "legal_class": null }, { "id": 58, "slug": "noopept", "name": "Noopept", "aliases": [ "GVS-111", "omberacetam", "DVD-111", "SGS-111", "Omberacetam (INN)", "N-phenylacetyl-L-prolylglycine ethyl ester", "N-phenylacetylprolylglycine ethyl ester", "Benzylcarbonyl-Pro-Gly-OEt", "Noopept\u00ae", "\u041d\u043e\u043e\u043f\u0435\u043f\u0442" ], "type": "Non-peptide", "category": "Cognitive research compounds", "goals_use_cases": [ "cognition", "focus", "mood", "focus / attention", "memory / learning support (discussed)", "verbal fluency / word-finding (community)", "mental clarity / brain fog (discussed)", "mood / mild anxiolytic component (trial + community)", "study / deep-work performance", "neuroprotection discussion", "post-traumatic / vascular MCI discussion (Russian clinical history)", "vs-piracetam low-mg racetam-class alternative" ], "delivery_methods": [ "oral", "sublingual" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "noopept", "GVS-111", "DVD-111", "SGS-111", "omberacetam", "Omberacetam (INN)", "cognition", "focus / attention", "memory / learning support (discussed)", "verbal fluency / word-finding (community)", "mental clarity / brain fog (discussed)", "mood / mild anxiolytic component (trial + community)" ], "feel_search": [ "cognition", "focus / attention", "memory / learning support (discussed)", "verbal fluency / word-finding (community)", "mental clarity / brain fog (discussed)", "mood / mild anxiolytic component (trial + community)" ], "summary": "Noopept (omberacetam) is a synthetic peptide-derived nootropic, usually discussed for memory and focus at low oral milligram amounts.", "search_blob": "noopept noopept gvs-111 omberacetam dvd-111 sgs-111 omberacetam (inn) n-phenylacetyl-l-prolylglycine ethyl ester n-phenylacetylprolylglycine ethyl ester benzylcarbonyl-pro-gly-oet noopept\u00ae \u043d\u043e\u043e\u043f\u0435\u043f\u0442 noopept gvs-111 dvd-111 sgs-111 omberacetam omberacetam (inn) cognition focus / attention memory / learning support (discussed) verbal fluency / word-finding (community) mental clarity / brain fog (discussed) mood / mild anxiolytic component (trial + community) cognition focus mood focus / attention memory / learning support (discussed) verbal fluency / word-finding (community) mental clarity / brain fog (discussed) mood / mild anxiolytic component (trial + community) study / deep-work performance neuroprotection discussion post-traumatic / vascular mci discussion (russian clinical history) vs-piracetam low-mg racetam-class alternative cognition focus / attention memory / learning support (discussed) verbal fluency / word-finding (community) mental clarity / brain fog (discussed) mood / mild anxiolytic component (trial + community) noopept (omberacetam) is a synthetic peptide-derived nootropic, usually discussed for memory and focus at low oral milligram amounts. some describe clearer thinking, sensory vividness or easier focus; others notice nothing or discomfort. route, caffeine, other nootropics and sleep make comparisons difficult. noopept is an oral compound people look up for cognition. cleaner task stickiness without classic stim jitter for many logs; still confounded by caffeine and sleep. \u201c~1000\u00d7 more potent than piracetam\u201d is a dose-scale slogan (tens of mg vs grams) \u2014 not a proven 1000\u00d7 efficacy multiplier in humans. cognitive research compounds non-peptide systemic cns-oriented small molecule used mainly by oral or sublingual routes; intranasal use is a minority experiment. systemic whole-body circulating", "legal_class": null }, { "id": 59, "slug": "methylene-blue", "name": "Methylene Blue", "aliases": [ "MB", "methylthioninium chloride", "USP methylene blue discussion", "methylthioninium", "USP methylene blue", "pharmaceutical-grade methylene blue", "ProvayBlue (clinical IV brand context)", "Proveblue (clinical brand context)", "methylene blue USP", "MB drops / oral solution (community form)", "LMTM / LMTX / TRx0237 / hydromethylthionine (related tau-aggregation derivative \u2014 not the same consumer MB)", "Rember (older methylthioninium chloride AD program context)" ], "type": "Non-peptide", "category": "Mitochondrial & metabolic compounds", "goals_use_cases": [ "focus", "cognition", "mitochondrial discussion", "mood", "cognition / focus / mental clarity (discussed)", "memory retrieval and short-term memory (small human imaging work)", "mitochondrial electron-transport / cellular energy discussion", "mood / residual bipolar depression adjunct research (historical)", "longevity / healthy-aging mito tonic talk", "neuroprotection and neurodegenerative model interest", "energy / mental fatigue / brain-fog narratives", "red-light / photobiomodulation stack culture", "clinical methemoglobinemia (FDA-approved IV indication)", "ICU / perioperative vasoplegia and surgical dye contexts (hospital only)", "PTSD extinction / exposure-therapy adjunct research interest (historical trials)" ], "delivery_methods": [ "oral", "IV" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "methylene-blue", "methylene blue", "methyleneblue", "MB", "methylthioninium chloride", "methylthioninium", "brain fog", "focus", "blue urine", "mito", "G6PD", "SSRI", "USP", "aquarium" ], "feel_search": [ "brain fog", "focus", "blue urine", "mito", "methylene blue", "G6PD", "SSRI", "aquarium" ], "summary": "Methylene blue is a dye and medicine, also used experimentally in low oral amounts for focus and energy.", "search_blob": "methylene blue methylene-blue mb methylthioninium chloride usp methylene blue discussion methylthioninium usp methylene blue pharmaceutical-grade methylene blue provayblue (clinical iv brand context) proveblue (clinical brand context) methylene blue usp mb drops / oral solution (community form) lmtm / lmtx / trx0237 / hydromethylthionine (related tau-aggregation derivative \u2014 not the same consumer mb) rember (older methylthioninium chloride ad program context) methylene-blue methylene blue methyleneblue mb methylthioninium chloride methylthioninium brain fog focus blue urine mito g6pd ssri usp aquarium focus cognition mitochondrial discussion mood cognition / focus / mental clarity (discussed) memory retrieval and short-term memory (small human imaging work) mitochondrial electron-transport / cellular energy discussion mood / residual bipolar depression adjunct research (historical) longevity / healthy-aging mito tonic talk neuroprotection and neurodegenerative model interest energy / mental fatigue / brain-fog narratives red-light / photobiomodulation stack culture clinical methemoglobinemia (fda-approved iv indication) icu / perioperative vasoplegia and surgical dye contexts (hospital only) ptsd extinction / exposure-therapy adjunct research interest (historical trials) brain fog focus blue urine mito methylene blue g6pd ssri aquarium methylene blue is a dye and medicine, also used experimentally in low oral amounts for focus and energy. methylene blue is an oral compound people look up for focus and mental energy. people post about sharper focus, less fog, and more daytime energy. people pair a low oral amount with red light, coq10, or an nad precursor when they want mental energy and a cleaner focus. mitochondrial & metabolic compounds non-peptide systemic systemic dye with oral and intravenous exposure; clinical methemoglobinemia use and community nootropic use are different evidence contexts. systemic whole-body circulating", "legal_class": null }, { "id": 60, "slug": "metformin", "name": "Metformin", "aliases": [ "Glucophage", "metformin HCl", "Glucophage XR", "metformin hydrochloride", "Fortamet", "Glumetza", "Riomet", "metformin IR", "metformin XR / ER / SR", "metformin DR (delayed-release research formulations)", "dimethylbiguanide (class/historical)", "biguanide (class)" ], "type": "Non-peptide", "category": "Metabolic & longevity adjacents", "goals_use_cases": [ "metabolic health", "longevity", "glucose", "fat loss adjacency", "longevity / geroscience baseline", "glucose / HbA1c control", "insulin sensitivity", "type 2 diabetes (clinical context)", "prediabetes / diabetes-delay discussion (DPP)", "PCOS / insulin-resistance narratives", "fat-loss / recomp adjacency (mild)", "AMPK / nutrient-sensing interest", "bodybuilding cut / insulin-partitioning talk", "CR-mimetic framing", "cancer-risk observational interest" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "metformin", "Glucophage", "Glucophage XR", "metformin HCl", "metformin hydrochloride", "Fortamet", "TAME", "longevity metformin", "glucophage xr", "metabolic health", "longevity / geroscience baseline", "glucose / hba1c control", "insulin sensitivity", "type 2 diabetes (clinical context)", "prediabetes / diabetes-delay discussion (dpp)" ], "feel_search": [ "metabolic health", "longevity / geroscience baseline", "glucose / hba1c control", "insulin sensitivity", "type 2 diabetes (clinical context)", "prediabetes / diabetes-delay discussion (dpp)" ], "summary": "Metformin is an oral biguanide medicine for glucose control, also discussed in PCOS and longevity; immediate-release and extended-release forms can feel different.", "search_blob": "metformin metformin glucophage metformin hcl glucophage xr metformin hydrochloride fortamet glumetza riomet metformin ir metformin xr / er / sr metformin dr (delayed-release research formulations) dimethylbiguanide (class/historical) biguanide (class) metformin glucophage glucophage xr metformin hcl metformin hydrochloride fortamet tame longevity metformin glucophage xr metabolic health longevity / geroscience baseline glucose / hba1c control insulin sensitivity type 2 diabetes (clinical context) prediabetes / diabetes-delay discussion (dpp) metabolic health longevity glucose fat loss adjacency longevity / geroscience baseline glucose / hba1c control insulin sensitivity type 2 diabetes (clinical context) prediabetes / diabetes-delay discussion (dpp) pcos / insulin-resistance narratives fat-loss / recomp adjacency (mild) ampk / nutrient-sensing interest bodybuilding cut / insulin-partitioning talk cr-mimetic framing cancer-risk observational interest metabolic health longevity / geroscience baseline glucose / hba1c control insulin sensitivity type 2 diabetes (clinical context) prediabetes / diabetes-delay discussion (dpp) metformin is an oral biguanide medicine for glucose control, also discussed in pcos and longevity; immediate-release and extended-release forms can feel different. early experiences can involve diarrhea or nausea, but some feel mainly fatigue and others little discomfort. users in the reviewed thread often preferred extended release, though it did not eliminate early side effects for everyone. metformin is an oral medicine people look up for longevity. mild loss or weight-neutral; far weaker than glp-1 / dual agonists for body-weight. metabolic & longevity adjacents non-peptide systemic systemic \u2014 oral biguanide with whole-body glucose and nutrient-sensing effects (liver glucose output, insulin sensitivity, gut/incretin pathways). systemic whole-body circulating", "legal_class": null }, { "id": 61, "slug": "enclomiphene", "name": "Enclomiphene", "aliases": [ "Androxal-class discussion", "trans-clomiphene", "Enclomiphene citrate", "Enclomifene (INN-style spelling)", "Androxal (Repros development designation; not marketed)", "EnCyzix (EU development designation; not authorized)", "Enclomiphene HCl (compounded salt discussion)", "EC / enclo (forum shorthand)" ], "type": "Non-peptide", "category": "Hormone modulators", "goals_use_cases": [ "hormone axis", "libido", "fertility discussion", "muscle preservation", "secondary hypogonadism discussion", "PCT / post-cycle talk", "TRT alternative (discussed)", "energy / vitality (discussed)", "post-TRT restart / HPTA recovery talk", "sperm-parameter preservation vs exogenous T" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "enclomiphene", "Enclomiphene citrate", "Enclomifene (INN-style spelling)", "trans-clomiphene", "Androxal (Repros development designation; not marketed)", "EnCyzix (EU development designation; not authorized)", "low t", "libido", "pct", "clomid" ], "feel_search": [ "low t", "libido", "pct", "clomid" ], "summary": "Enclomiphene is the trans isomer of clomiphene, an oral selective estrogen receptor modulator discussed for raising the body\u2019s own testosterone.", "search_blob": "enclomiphene enclomiphene androxal-class discussion trans-clomiphene enclomiphene citrate enclomifene (inn-style spelling) androxal (repros development designation; not marketed) encyzix (eu development designation; not authorized) enclomiphene hcl (compounded salt discussion) ec / enclo (forum shorthand) enclomiphene enclomiphene citrate enclomifene (inn-style spelling) trans-clomiphene androxal (repros development designation; not marketed) encyzix (eu development designation; not authorized) low t libido pct clomid hormone axis libido fertility discussion muscle preservation secondary hypogonadism discussion pct / post-cycle talk trt alternative (discussed) energy / vitality (discussed) post-trt restart / hpta recovery talk sperm-parameter preservation vs exogenous t low t libido pct clomid enclomiphene is the trans isomer of clomiphene, an oral selective estrogen receptor modulator discussed for raising the body\u2019s own testosterone. one early user reports gym recovery and fullness, but libido remains mixed. they also take tongkat ali and lack a recent untreated hormone baseline. enclomiphene is an oral medicine people look up for energy in men with secondary hypogonadism. framed as preserving spermatogenesis while restoring t. 12.5 mg daily is the clinic start people copy. vision / mood sides still get mentioned. hormone modulators non-peptide systemic systemic \u2014 oral serm (pure trans isomer of clomiphene); blocks central estrogen feedback so lh/fsh and endogenous testicular testosterone rise axis-wide. systemic whole-body circulating", "legal_class": null }, { "id": 62, "slug": "rad-140", "name": "RAD-140", "aliases": [ "Testolone", "RAD140", "RAD 140", "Vosilasarm (INN / development naming)", "EP0062 (reformulated clinical code)", "Testalone (common misspelling in literature and forums)", "Radius RAD140 (developer-adjacent search string)" ], "type": "Non-peptide", "category": "SARMs (adjacent discourse)", "goals_use_cases": [ "muscle growth", "performance", "fat loss adjacency", "strength", "body recomposition", "lean mass retention (discussed)", "bulking (community framing)", "cutting with muscle hold (discussed)", "dry / dense look vs wetter orals (forum typology)", "neuroprotection research interest (animal / in-vitro, not gym use)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "rad-140", "rad 140", "rad140", "Testolone", "Vosilasarm (INN / development naming)", "EP0062 (reformulated clinical code)", "strength", "recomp", "suppression", "sarm", "testolone" ], "feel_search": [ "strength", "recomp", "suppression", "sarm", "testolone" ], "summary": "RAD-140 (Testolone/vosilasarm) is an investigational oral nonsteroidal SARM acting on androgen receptors, discussed for muscle and strength.", "search_blob": "rad-140 rad-140 testolone rad140 rad 140 vosilasarm (inn / development naming) ep0062 (reformulated clinical code) testalone (common misspelling in literature and forums) radius rad140 (developer-adjacent search string) rad-140 rad 140 rad140 testolone vosilasarm (inn / development naming) ep0062 (reformulated clinical code) strength recomp suppression sarm testolone muscle growth performance fat loss adjacency strength body recomposition lean mass retention (discussed) bulking (community framing) cutting with muscle hold (discussed) dry / dense look vs wetter orals (forum typology) neuroprotection research interest (animal / in-vitro, not gym use) strength recomp suppression sarm testolone rad-140 (testolone/vosilasarm) is an investigational oral nonsteroidal sarm acting on androgen receptors, discussed for muscle and strength. one cut-phase user reported strength gains with more aggression and restless sleep, followed by lower drive and slower recovery after stopping. rad-140 is an oral compound people look up for muscle. fat loss with muscle hold on a deficit is frequently logged; calories and cardio usually co-credited. not a legal supplement. bloodwork talk is part of taking this seriously. sarms (adjacent discourse) non-peptide systemic systemic oral sarm \u2014 whole-body exposure with muscle/bone-biased ar agonism talk; not a local inject and not a peptide. systemic whole-body circulating", "legal_class": null }, { "id": 63, "slug": "lgd-4033", "name": "LGD-4033", "aliases": [ "Ligandrol", "VK5211 discussion", "LGD", "VK5211", "VK-5211", "LGD4033", "LGD 4033", "Anabolicum", "LGD4033 (Ligandrol)" ], "type": "Non-peptide", "category": "SARMs (adjacent discourse)", "goals_use_cases": [ "muscle", "muscle growth", "performance", "lean mass / muscle growth (primary community use)", "strength and compound-lift progression (discussed)", "performance / training quality", "body recomposition (muscle-hold + fat-loss phases, discussed)", "bulking phases (community \u201charder oral SARM\u201d framing)", "recovery continuity during hard training blocks (discussed)", "clinical-adjacent muscle-wasting / hip-fracture recovery research (VK5211; not physique approval)", "bone / osteosarcopenia research interest (developmental history)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "lgd-4033", "lgd 4033", "lgd4033", "Ligandrol", "VK5211", "VK-5211", "lean mass / muscle growth (primary community use)", "strength and compound-lift progression (discussed)", "performance / training quality", "body recomposition (muscle-hold + fat-loss phases, discussed)", "bulking phases (community \u201charder oral sarm\u201d framing)", "recovery continuity during hard training blocks (discussed)" ], "feel_search": [ "lean mass / muscle growth (primary community use)", "strength and compound-lift progression (discussed)", "performance / training quality", "body recomposition (muscle-hold + fat-loss phases, discussed)", "bulking phases (community \u201charder oral sarm\u201d framing)", "recovery continuity during hard training blocks (discussed)" ], "summary": "LGD-4033 (Ligandrol/VK5211) is an experimental oral SARM, discussed for muscle and strength; it is not the same drug as LGD-3303.", "search_blob": "lgd-4033 lgd-4033 ligandrol vk5211 discussion lgd vk5211 vk-5211 lgd4033 lgd 4033 anabolicum lgd4033 (ligandrol) lgd-4033 lgd 4033 lgd4033 ligandrol vk5211 vk-5211 lean mass / muscle growth (primary community use) strength and compound-lift progression (discussed) performance / training quality body recomposition (muscle-hold + fat-loss phases, discussed) bulking phases (community \u201charder oral sarm\u201d framing) recovery continuity during hard training blocks (discussed) muscle muscle growth performance lean mass / muscle growth (primary community use) strength and compound-lift progression (discussed) performance / training quality body recomposition (muscle-hold + fat-loss phases, discussed) bulking phases (community \u201charder oral sarm\u201d framing) recovery continuity during hard training blocks (discussed) clinical-adjacent muscle-wasting / hip-fracture recovery research (vk5211; not physique approval) bone / osteosarcopenia research interest (developmental history) lean mass / muscle growth (primary community use) strength and compound-lift progression (discussed) performance / training quality body recomposition (muscle-hold + fat-loss phases, discussed) bulking phases (community \u201charder oral sarm\u201d framing) recovery continuity during hard training blocks (discussed) lgd-4033 (ligandrol/vk5211) is an experimental oral sarm, discussed for muscle and strength; it is not the same drug as lgd-3303. one 11-day report described better lifts and recovery but also nausea, night sweats, flatter mood and worse aerobic capacity, leading the author to stop. a fuller look may partly reflect water. lgd-4033 is an oral sarm people look up for muscle and strength. often framed as drier or cleaner than \u201cwet\u201d oral aas. sarms (adjacent discourse) non-peptide systemic systemic oral sarm \u2014 whole-body androgen-receptor signaling with tissue-selective framing (muscle/bone favored over prostate in preclinical models). systemic whole-body circulating", "legal_class": null }, { "id": 64, "slug": "ostarine", "name": "Ostarine", "aliases": [ "MK-2866", "Enobosarm", "GTx-024", "S-22", "OTR-AC", "VERU-024", "MK2866", "Enobosarm (INN / clinical naming)" ], "type": "Non-peptide", "category": "SARMs (adjacent discourse)", "goals_use_cases": [ "muscle growth", "recomposition", "performance", "lean mass preservation (discussed)", "cutting / anti-catabolism (discussed)", "strength continuity (discussed)", "body composition", "injury-return training (discussed)", "GLP-1 lean-mass hold adjacency (trial + discussion)", "beginner SARM entry point (community framing)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "ostarine", "MK-2866", "Enobosarm", "GTx-024", "S-22", "OTR-AC", "recomp", "sarm", "suppression", "enobosarm" ], "feel_search": [ "recomp", "sarm", "suppression", "enobosarm" ], "summary": "Ostarine (enobosarm) is an experimental oral SARM discussed for retaining muscle during cuts and improving training recovery.", "search_blob": "ostarine ostarine mk-2866 enobosarm gtx-024 s-22 otr-ac veru-024 mk2866 enobosarm (inn / clinical naming) ostarine mk-2866 enobosarm gtx-024 s-22 otr-ac recomp sarm suppression enobosarm muscle growth recomposition performance lean mass preservation (discussed) cutting / anti-catabolism (discussed) strength continuity (discussed) body composition injury-return training (discussed) glp-1 lean-mass hold adjacency (trial + discussion) beginner sarm entry point (community framing) recomp sarm suppression enobosarm ostarine (enobosarm) is an experimental oral sarm discussed for retaining muscle during cuts and improving training recovery. some describe better strength retention or recovery, others little effect. fatigue, mood changes and other symptoms can appear during longer runs, especially in changing stacks. ostarine is an oral compound people look up for muscle. some report easier strength hold in a deficit or slightly better gym recovery; others still neutral. clinic studies used 1\u20133 mg. gym charts are often higher. sarms (adjacent discourse) non-peptide systemic systemic oral sarm: whole-body androgen-receptor effects, with muscle/bone selectivity claims\u2014not a locally targeted injection. systemic whole-body circulating", "legal_class": null }, { "id": 65, "slug": "cardarine", "name": "Cardarine", "aliases": [ "GW501516", "GW1516", "Endurobol", "GW-501516", "GW 501516", "GW-1516", "GW 1516", "GW-501,516", "GSK-516", "Cardarine (Endurobol)" ], "type": "Non-peptide", "category": "Metabolic research compounds", "goals_use_cases": [ "endurance", "fat loss", "performance", "lipid profile (discussed)", "metabolic research", "cardio capacity (discussed)", "body recomposition (discussed)", "fatty-acid oxidation (discussed)", "contest / race prep cardio assist (discussed)", "Tren cardio offset (discussed)", "HDL support talk in PED users (discussed)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "cardarine", "GW501516", "GW-501516", "GW 501516", "GW1516", "GW-1516", "endurance", "cardio", "zone 2", "cancer scare", "not a SARM", "lipids", "HDL", "pre cardio", "WADA", "third lung" ], "feel_search": [ "endurance", "cardio", "zone 2", "cancer scare", "not a SARM", "lipids", "HDL", "pre cardio", "WADA", "third lung" ], "summary": "Cardarine (GW501516) is a non-peptide PPAR\u03b4 agonist investigated for metabolism and discussed for endurance; it is not a SARM.", "search_blob": "cardarine cardarine gw501516 gw1516 endurobol gw-501516 gw 501516 gw-1516 gw 1516 gw-501,516 gsk-516 cardarine (endurobol) cardarine gw501516 gw-501516 gw 501516 gw1516 gw-1516 endurance cardio zone 2 cancer scare not a sarm lipids hdl pre cardio wada third lung endurance fat loss performance lipid profile (discussed) metabolic research cardio capacity (discussed) body recomposition (discussed) fatty-acid oxidation (discussed) contest / race prep cardio assist (discussed) tren cardio offset (discussed) hdl support talk in ped users (discussed) endurance cardio zone 2 cancer scare not a sarm lipids hdl pre cardio wada third lung cardarine (gw501516) is a non-peptide ppar\u03b4 agonist investigated for metabolism and discussed for endurance; it is not a sarm. a runner\u2019s log reports no clear endurance or heart-rate benefit after about two weeks, despite pushing training. minor fitness gains were attributed to the training plan. cardarine is an oral compound people look up for endurance. 2026 cut diaries still lead with easier incline walks and race-block cardio, then the cancer googling. not a sarm. the rodent cancer story is why careful threads stay wary. metabolic research compounds non-peptide systemic systemic \u2014 oral gw501516 is a ppar\u03b4 agonist, not a sarm; endurance and lipid discussion carries an unresolved rodent tumor warning. systemic whole-body circulating", "legal_class": null }, { "id": 66, "slug": "sr9009", "name": "SR9009", "aliases": [ "Stenabolic", "SR-9009", "SR 9009", "REV-ERB agonist SR9009", "Rev-ErbA agonist SR9009", "Scripps REV-ERB ligand SR9009" ], "type": "Non-peptide", "category": "Metabolic research compounds", "goals_use_cases": [ "endurance", "fat loss", "performance", "metabolic research", "mitochondrial support (discussed)", "body composition", "cardio capacity (discussed)", "lipid markers (preclinical discussion)", "exercise-mimetic research talk", "cut-phase conditioning" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "sr9009", "Stenabolic", "SR-9009", "SR 9009", "REV-ERB agonist SR9009", "Rev-ErbA agonist SR9009", "endurance", "fat loss", "performance", "metabolic research", "mitochondrial support (discussed)", "body composition" ], "feel_search": [ "endurance", "fat loss", "performance", "metabolic research", "mitochondrial support (discussed)", "body composition" ], "summary": "SR9009, nicknamed Stenabolic, is an experimental small-molecule REV-ERB receptor agonist discussed for metabolism and endurance.", "search_blob": "sr9009 sr9009 stenabolic sr-9009 sr 9009 rev-erb agonist sr9009 rev-erba agonist sr9009 scripps rev-erb ligand sr9009 sr9009 stenabolic sr-9009 sr 9009 rev-erb agonist sr9009 rev-erba agonist sr9009 endurance fat loss performance metabolic research mitochondrial support (discussed) body composition endurance fat loss performance metabolic research mitochondrial support (discussed) body composition cardio capacity (discussed) lipid markers (preclinical discussion) exercise-mimetic research talk cut-phase conditioning endurance fat loss performance metabolic research mitochondrial support (discussed) body composition sr9009, nicknamed stenabolic, is an experimental small-molecule rev-erb receptor agonist discussed for metabolism and endurance. the thread includes no effect, good sleep during a busy stacked regimen, and warmth with poorer sleep in another account. sr9009 is an oral compound people look up for endurance. some report \u201ccleaner\u201d drive or readiness without jitter; others report nothing or early lethargy \u2014 inconsistent. metabolic research compounds non-peptide systemic systemic \u2014 experimental rev-erb ligand studied in whole-body circadian, metabolic and skeletal-muscle programs; not a peptide. systemic whole-body circulating", "legal_class": null }, { "id": 68, "slug": "survodutide", "name": "Survodutide", "aliases": [ "BI 456906", "glucagon/GLP-1 dual agonist discussion", "BI456906", "BI-456906", "glucagon/GLP-1 dual agonist", "GCGR/GLP-1R dual agonist", "Zealand/Boehringer dual agonist" ], "type": "Peptide", "category": "Metabolic / GLP-1 class", "goals_use_cases": [ "fat loss", "metabolic health", "liver fat discussion", "liver fat / MASLD discussion", "MASH / fibrosis research interest", "appetite control", "body composition (fat vs lean discussion)", "obesity management research", "cardiometabolic risk discussion", "visceral fat reduction (trial imaging)", "type 2 diabetes weight/glucose research (SYNCHRONIZE-2 program)" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "survodutide", "BI 456906", "BI456906", "BI-456906", "glucagon/GLP-1 dual agonist", "GCGR/GLP-1R dual agonist", "fat loss", "metabolic health", "liver fat / masld discussion", "mash / fibrosis research interest", "appetite control", "body composition (fat vs lean discussion)" ], "feel_search": [ "fat loss", "metabolic health", "liver fat / masld discussion", "mash / fibrosis research interest", "appetite control", "body composition (fat vs lean discussion)" ], "summary": "Survodutide (BI 456906) is an investigational peptide activating GLP-1 and glucagon receptors, studied for obesity and liver disease.", "search_blob": "survodutide survodutide bi 456906 glucagon/glp-1 dual agonist discussion bi456906 bi-456906 glucagon/glp-1 dual agonist gcgr/glp-1r dual agonist zealand/boehringer dual agonist survodutide bi 456906 bi456906 bi-456906 glucagon/glp-1 dual agonist gcgr/glp-1r dual agonist fat loss metabolic health liver fat / masld discussion mash / fibrosis research interest appetite control body composition (fat vs lean discussion) fat loss metabolic health liver fat discussion liver fat / masld discussion mash / fibrosis research interest appetite control body composition (fat vs lean discussion) obesity management research cardiometabolic risk discussion visceral fat reduction (trial imaging) type 2 diabetes weight/glucose research (synchronize-2 program) fat loss metabolic health liver fat / masld discussion mash / fibrosis research interest appetite control body composition (fat vs lean discussion) survodutide (bi 456906) is an investigational peptide activating glp-1 and glucagon receptors, studied for obesity and liver disease. some users combining it with tirzepatide describe more energy and quieter appetite; a blinded trial user felt no difference after stopping. survodutide is a peptide people look up for fat loss. \u201cappetite quieting\u201d is the dominant dual-agonist discussion theme, but direct survodutide logs are sparse. far fewer personal research-chem logs than sema/tirz/reta; most \u201cdosing talk\u201d is trial titration charts, not thick forum n=1 libraries. metabolic / glp-1 class peptide systemic systemic \u2014 once-weekly glucagon/glp-1 dual agonist for whole-body appetite, weight, energy-expenditure, and hepatic fat effects. systemic whole-body circulating", "legal_class": null }, { "id": 69, "slug": "mazdutide", "name": "Mazdutide", "aliases": [ "IBI362", "LY3305677 discussion", "IBI-362", "LY3305677", "LY-3305677", "OXM3 (development / oxyntomodulin-analog discussions)", "Xinermei", "\u4fe1\u8bfa\u7f8e (China brand name)", "GLP-1/glucagon dual agonist", "GCG/GLP-1 dual agonist", "mazdutide peptide", "Mezdutide (common misspelling in dose lists)" ], "type": "Peptide", "category": "Metabolic / GLP-1 class", "goals_use_cases": [ "fat loss", "metabolic health", "fat loss / chronic weight management", "appetite control / food-noise reduction", "glycemic control in type 2 diabetes (China-approved indication + DREAMS program)", "liver fat / MAFLD reduction (trial + GLORY-3 vs sema design)", "waist circumference and cardiometabolic markers (BP, lipids, uric acid)", "obesity research (moderate-to-severe / high-dose 9 mg program)", "type 2 diabetes research (China NMPA approved; Western still investigational)", "energy-expenditure / \u201cglucagon arm burns\u201d framing (mechanistic + community lore)", "gray-market dual-agonist alternative when sema/tirz access is constrained (community talk \u2014 not endorsement)" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "mazdutide", "IBI362", "IBI-362", "LY3305677", "LY-3305677", "OXM3 (development / oxyntomodulin-analog discussions)", "fat loss / chronic weight management", "appetite control / food-noise reduction", "metabolic health", "glycemic control in type 2 diabetes (china-approved indication + dreams program)", "liver fat / mafld reduction (trial + glory-3 vs sema design)", "waist circumference and cardiometabolic markers (bp, lipids, uric acid)" ], "feel_search": [ "fat loss / chronic weight management", "appetite control / food-noise reduction", "metabolic health", "glycemic control in type 2 diabetes (china-approved indication + dreams program)", "liver fat / mafld reduction (trial + glory-3 vs sema design)", "waist circumference and cardiometabolic markers (bp, lipids, uric acid)" ], "summary": "Mazdutide is a dual GLP-1/glucagon receptor agonist peptide developed for weight and glucose management, distinct from tirzepatide\u2019s receptor combination.", "search_blob": "mazdutide mazdutide ibi362 ly3305677 discussion ibi-362 ly3305677 ly-3305677 oxm3 (development / oxyntomodulin-analog discussions) xinermei \u4fe1\u8bfa\u7f8e (china brand name) glp-1/glucagon dual agonist gcg/glp-1 dual agonist mazdutide peptide mezdutide (common misspelling in dose lists) mazdutide ibi362 ibi-362 ly3305677 ly-3305677 oxm3 (development / oxyntomodulin-analog discussions) fat loss / chronic weight management appetite control / food-noise reduction metabolic health glycemic control in type 2 diabetes (china-approved indication + dreams program) liver fat / mafld reduction (trial + glory-3 vs sema design) waist circumference and cardiometabolic markers (bp, lipids, uric acid) fat loss metabolic health fat loss / chronic weight management appetite control / food-noise reduction glycemic control in type 2 diabetes (china-approved indication + dreams program) liver fat / mafld reduction (trial + glory-3 vs sema design) waist circumference and cardiometabolic markers (bp, lipids, uric acid) obesity research (moderate-to-severe / high-dose 9 mg program) type 2 diabetes research (china nmpa approved; western still investigational) energy-expenditure / \u201cglucagon arm burns\u201d framing (mechanistic + community lore) gray-market dual-agonist alternative when sema/tirz access is constrained (community talk \u2014 not endorsement) fat loss / chronic weight management appetite control / food-noise reduction metabolic health glycemic control in type 2 diabetes (china-approved indication + dreams program) liver fat / mafld reduction (trial + glory-3 vs sema design) waist circumference and cardiometabolic markers (bp, lipids, uric acid) mazdutide is a dual glp-1/glucagon receptor agonist peptide developed for weight and glucose management, distinct from tirzepatide\u2019s receptor combination. mazdutide is a peptide people look up for fat loss and appetite. first appetite drop and early fullness common; nausea/loose stools often appear after the first 1\u20132 injections. metabolic / glp-1 class peptide systemic systemic \u2014 a once-weekly glp-1/glucagon dual agonist studied for appetite, weight, glucose and liver-metabolic effects. systemic whole-body circulating", "legal_class": null }, { "id": 70, "slug": "orforglipron", "name": "Orforglipron", "aliases": [ "LY3502970", "oral non-peptide GLP-1 agonist", "Foundayo (branded oral orforglipron \u2014 weight indication discussion)", "Oral non-peptide GLP-1 agonist", "Oral small-molecule GLP-1 RA", "Lilly oral GLP-1 (discussion shorthand)", "Orforglipron pill (forum shorthand)", "Orf / orfor (forum shorthand)" ], "type": "Non-peptide", "category": "Metabolic / GLP-1 class", "goals_use_cases": [ "fat loss", "appetite control", "glucose", "fat loss / obesity weight management", "appetite control / food-noise reduction", "glucose / glycemic discussion (T2D programs)", "weight management without injections", "metabolic / cardiometabolic health markers", "type 2 diabetes\u2013adjacent research and ACHIEVE program interest", "oral switch / maintenance after injectable incretins (ATTAIN-MAINTAIN)", "needle-averse GLP-1 access interest", "primary-care scalable oral GLP-1 talk" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "orforglipron", "LY3502970", "Foundayo (branded oral orforglipron \u2014 weight indication discussion)", "Oral non-peptide GLP-1 agonist", "Oral small-molecule GLP-1 RA", "Lilly oral GLP-1 (discussion shorthand)", "Foundayo", "oral GLP-1", "food noise", "nausea", "any time", "Rybelsus", "oral Wegovy", "switch", "hair loss", "foundayo", "rybelsus", "oral wegovy", "pill" ], "feel_search": [ "foundayo", "oral GLP-1", "food noise", "nausea", "any time", "rybelsus", "oral wegovy", "switch", "hair loss", "pill" ], "summary": "Orforglipron is a non-peptide GLP-1 pill used for weight management; people look it up for reduced appetite without injections.", "search_blob": "orforglipron orforglipron ly3502970 oral non-peptide glp-1 agonist foundayo (branded oral orforglipron \u2014 weight indication discussion) oral non-peptide glp-1 agonist oral small-molecule glp-1 ra lilly oral glp-1 (discussion shorthand) orforglipron pill (forum shorthand) orf / orfor (forum shorthand) orforglipron ly3502970 foundayo (branded oral orforglipron \u2014 weight indication discussion) oral non-peptide glp-1 agonist oral small-molecule glp-1 ra lilly oral glp-1 (discussion shorthand) foundayo oral glp-1 food noise nausea any time rybelsus oral wegovy switch hair loss foundayo rybelsus oral wegovy pill fat loss appetite control glucose fat loss / obesity weight management appetite control / food-noise reduction glucose / glycemic discussion (t2d programs) weight management without injections metabolic / cardiometabolic health markers type 2 diabetes\u2013adjacent research and achieve program interest oral switch / maintenance after injectable incretins (attain-maintain) needle-averse glp-1 access interest primary-care scalable oral glp-1 talk foundayo oral glp-1 food noise nausea any time rybelsus oral wegovy switch hair loss pill orforglipron is a non-peptide glp-1 pill used for weight management; people look it up for reduced appetite without injections. orforglipron is an oral compound people look up for fat loss. clearer appetite drop and earlier meal stop for responders. gi still hits on the monthly climb. mean loss trails high-dose tirz/reta, so people argue convenience vs ceiling. metabolic / glp-1 class non-peptide systemic systemic oral glp-1 small molecule, not a peptide; appetite, satiety, gastric-emptying and glucose effects extend beyond the gut. systemic whole-body circulating", "legal_class": null }, { "id": 71, "slug": "pemvidutide", "name": "Pemvidutide", "aliases": [ "ALT-801", "GLP-1/glucagon dual agonist discussion", "Pemvidutide (Altimmune)", "GLP-1/glucagon dual agonist", "GLP-1R/GCGR dual agonist", "Balanced 1:1 GLP-1/glucagon coagonist", "EuPort GLP-1/glucagon dual agonist" ], "type": "Peptide", "category": "Metabolic / GLP-1 class", "goals_use_cases": [ "fat loss", "liver fat discussion", "metabolic health", "fat loss / obesity research", "liver fat / MASLD reduction", "MASH resolution discussion (biopsy-driven IMPACT data)", "body composition / lean-mass preservation talk", "appetite control (GLP-1 arm)", "energy-expenditure / fat-oxidation talk (glucagon arm)", "lipid and blood-pressure markers", "metabolic health without strong diabetes-drug framing", "alcohol use disorder (RECLAIM Phase 2 discussion)", "alcohol-associated liver disease pipeline talk (RESTORE program)" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "pemvidutide", "ALT-801", "Pemvidutide (Altimmune)", "GLP-1/glucagon dual agonist", "GLP-1R/GCGR dual agonist", "Balanced 1:1 GLP-1/glucagon coagonist", "fat loss / obesity research", "liver fat / masld reduction", "mash resolution discussion (biopsy-driven impact data)", "body composition / lean-mass preservation talk", "appetite control (glp-1 arm)", "energy-expenditure / fat-oxidation talk (glucagon arm)" ], "feel_search": [ "fat loss / obesity research", "liver fat / masld reduction", "mash resolution discussion (biopsy-driven impact data)", "body composition / lean-mass preservation talk", "appetite control (glp-1 arm)", "energy-expenditure / fat-oxidation talk (glucagon arm)" ], "summary": "Pemvidutide (ALT-801) is an investigational peptide that activates GLP-1 and glucagon receptors, studied for obesity and liver disease.", "search_blob": "pemvidutide pemvidutide alt-801 glp-1/glucagon dual agonist discussion pemvidutide (altimmune) glp-1/glucagon dual agonist glp-1r/gcgr dual agonist balanced 1:1 glp-1/glucagon coagonist euport glp-1/glucagon dual agonist pemvidutide alt-801 pemvidutide (altimmune) glp-1/glucagon dual agonist glp-1r/gcgr dual agonist balanced 1:1 glp-1/glucagon coagonist fat loss / obesity research liver fat / masld reduction mash resolution discussion (biopsy-driven impact data) body composition / lean-mass preservation talk appetite control (glp-1 arm) energy-expenditure / fat-oxidation talk (glucagon arm) fat loss liver fat discussion metabolic health fat loss / obesity research liver fat / masld reduction mash resolution discussion (biopsy-driven impact data) body composition / lean-mass preservation talk appetite control (glp-1 arm) energy-expenditure / fat-oxidation talk (glucagon arm) lipid and blood-pressure markers metabolic health without strong diabetes-drug framing alcohol use disorder (reclaim phase 2 discussion) alcohol-associated liver disease pipeline talk (restore program) fat loss / obesity research liver fat / masld reduction mash resolution discussion (biopsy-driven impact data) body composition / lean-mass preservation talk appetite control (glp-1 arm) energy-expenditure / fat-oxidation talk (glucagon arm) pemvidutide (alt-801) is an investigational peptide that activates glp-1 and glucagon receptors, studied for obesity and liver disease. the inspected liver-health thread discusses trial hopes; its personal success story is about tirzepatide, not pemvidutide. pemvidutide is an investigational peptide people look up for fat loss and appetite. less hunger / easier deficit once on effective weekly dose. metabolic / glp-1 class peptide systemic systemic once-weekly dual glp-1/glucagon agonist \u2014 whole-body appetite, weight, cardiometabolic, and liver-fat effects rather than a local tissue inject. systemic whole-body circulating", "legal_class": null }, { "id": 72, "slug": "amycretin", "name": "Amycretin", "aliases": [ "Novo amycretin", "oral/sc amylin+GLP-1 discussion", "Zenagamtide (INN / public naming; same molecule)", "NNC0487-0111", "NN9487 / NN 9487 (development code)", "Unimolecular amylin + GLP-1 dual agonist", "GLP-1 / amylin / calcitonin receptor agonist (trial framing)", "Oral amycretin (SNAC tablet discussion)", "Subcutaneous amycretin (once-weekly)" ], "type": "Peptide", "category": "Metabolic / GLP-1 class", "goals_use_cases": [ "fat loss", "appetite control", "fat loss / chronic weight management", "appetite control and meal-size reduction", "satiety / dual-pathway food-noise cut", "metabolic health / cardiometabolic interest", "type 2 diabetes weight + glycemic co-interest", "glucose / HbA1c discussion (T2D programs)", "oral GLP-1-class interest (daily tablet path)", "once-weekly injectable dual-agonist interest", "body recomposition interest (confounded; lean mass still at risk with large deficits)", "post-mono-GLP-1 / pipeline comparison talk (vs CagriSema, tirz, reta)" ], "delivery_methods": [ "oral", "subcutaneous" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "amycretin", "Zenagamtide (INN / public naming; same molecule)", "NNC0487-0111", "NN9487 / NN 9487 (development code)", "Novo amycretin", "Unimolecular amylin + GLP-1 dual agonist", "fat loss / chronic weight management", "appetite control and meal-size reduction", "satiety / dual-pathway food-noise cut", "metabolic health / cardiometabolic interest", "type 2 diabetes weight + glycemic co-interest", "glucose / hba1c discussion (t2d programs)" ], "feel_search": [ "fat loss / chronic weight management", "appetite control and meal-size reduction", "satiety / dual-pathway food-noise cut", "metabolic health / cardiometabolic interest", "type 2 diabetes weight + glycemic co-interest", "glucose / hba1c discussion (t2d programs)" ], "summary": "Amycretin is an investigational peptide that activates both GLP-1 and amylin receptors, being studied as an injection and oral weight-management drug.", "search_blob": "amycretin amycretin novo amycretin oral/sc amylin+glp-1 discussion zenagamtide (inn / public naming; same molecule) nnc0487-0111 nn9487 / nn 9487 (development code) unimolecular amylin + glp-1 dual agonist glp-1 / amylin / calcitonin receptor agonist (trial framing) oral amycretin (snac tablet discussion) subcutaneous amycretin (once-weekly) amycretin zenagamtide (inn / public naming; same molecule) nnc0487-0111 nn9487 / nn 9487 (development code) novo amycretin unimolecular amylin + glp-1 dual agonist fat loss / chronic weight management appetite control and meal-size reduction satiety / dual-pathway food-noise cut metabolic health / cardiometabolic interest type 2 diabetes weight + glycemic co-interest glucose / hba1c discussion (t2d programs) fat loss appetite control fat loss / chronic weight management appetite control and meal-size reduction satiety / dual-pathway food-noise cut metabolic health / cardiometabolic interest type 2 diabetes weight + glycemic co-interest glucose / hba1c discussion (t2d programs) oral glp-1-class interest (daily tablet path) once-weekly injectable dual-agonist interest body recomposition interest (confounded; lean mass still at risk with large deficits) post-mono-glp-1 / pipeline comparison talk (vs cagrisema, tirz, reta) fat loss / chronic weight management appetite control and meal-size reduction satiety / dual-pathway food-noise cut metabolic health / cardiometabolic interest type 2 diabetes weight + glycemic co-interest glucose / hba1c discussion (t2d programs) amycretin is an investigational peptide that activates both glp-1 and amylin receptors, being studied as an injection and oral weight-management drug. a self-described trial participant reports much quieter food noise and lower appetite over nine months, with persistent constipation. participation is unverified. amycretin is a peptide people look up for fat loss and appetite. strong appetite suppression. metabolic / glp-1 class peptide systemic systemic glp-1/amylin dual-agonist peptide for appetite and metabolic research; weekly subq and daily oral trial formulations. systemic whole-body circulating", "legal_class": null }, { "id": 73, "slug": "snap-8", "name": "SNAP-8", "aliases": [ "Acetyl Octapeptide-3", "SNAP8", "Snap-8", "SNAP-8\u2122 peptide solution C (Lipotec / Lubrizol trade form)", "SNAP-8 Amide (trade-form discussions)", "Acetyl Glutamyl Heptapeptide-1 / -3 (INCI/cross-name discussions \u2014 naming inconsistent across vendors)", "Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH\u2082" ], "type": "Peptide", "category": "Skin, hair & tissue remodeling", "goals_use_cases": [ "skin/hair", "anti-aging discussion", "expression lines / dynamic wrinkles", "forehead & crow's feet appearance", "glabellar / frown-line appearance", "cosmetic peptide routines", "non-injectable Botox-alternative talk", "fine-line smoothing narratives", "DIY multi-peptide serum building", "between-Botox maintenance talk", "minority gray-market meso / intradermal discussion" ], "delivery_methods": [ "topical" ], "discussion_popularity": "Medium", "reach": "Local", "misspellings_search_terms": [ "snap-8", "snap 8", "snap8", "Acetyl Octapeptide-3", "SNAP-8\u2122 peptide solution C (Lipotec / Lubrizol trade form)", "SNAP-8 Amide (trade-form discussions)", "skin/hair", "anti-aging discussion", "expression lines / dynamic wrinkles", "forehead & crow's feet appearance", "glabellar / frown-line appearance", "cosmetic peptide routines" ], "feel_search": [ "skin/hair", "anti-aging discussion", "expression lines / dynamic wrinkles", "forehead & crow's feet appearance", "glabellar / frown-line appearance", "cosmetic peptide routines" ], "summary": "SNAP-8 is acetyl octapeptide-3, an eight-amino-acid cosmetic peptide related to Argireline and marketed for expression lines.", "search_blob": "snap-8 snap-8 acetyl octapeptide-3 snap8 snap-8 snap-8\u2122 peptide solution c (lipotec / lubrizol trade form) snap-8 amide (trade-form discussions) acetyl glutamyl heptapeptide-1 / -3 (inci/cross-name discussions \u2014 naming inconsistent across vendors) ac-glu-glu-met-gln-arg-arg-ala-asp-nh\u2082 snap-8 snap 8 snap8 acetyl octapeptide-3 snap-8\u2122 peptide solution c (lipotec / lubrizol trade form) snap-8 amide (trade-form discussions) skin/hair anti-aging discussion expression lines / dynamic wrinkles forehead & crow's feet appearance glabellar / frown-line appearance cosmetic peptide routines skin/hair anti-aging discussion expression lines / dynamic wrinkles forehead & crow's feet appearance glabellar / frown-line appearance cosmetic peptide routines non-injectable botox-alternative talk fine-line smoothing narratives diy multi-peptide serum building between-botox maintenance talk minority gray-market meso / intradermal discussion skin/hair anti-aging discussion expression lines / dynamic wrinkles forehead & crow's feet appearance glabellar / frown-line appearance cosmetic peptide routines snap-8 is acetyl octapeptide-3, an eight-amino-acid cosmetic peptide related to argireline and marketed for expression lines. one user reported smoother forehead lines from a snap-8, matrixyl and argireline blend; another used a different peptide combination. snap-8 is a peptide people look up for skin. people report softens look of forehead, glabella/frown lines, and crow\u2019s feet with consistent twice-daily topical use. skin, hair & tissue remodeling peptide local local \u2014 a face serum, not a whole-body shot. local site pin topical", "legal_class": null }, { "id": 74, "slug": "argireline", "name": "Argireline", "aliases": [ "Acetyl Hexapeptide-8", "Argireline peptide", "Acetyl Hexapeptide-8 Amide", "Acetyl Hexapeptide-3 (legacy INCI / older literature naming \u2014 often treated as the same hexapeptide franchise)", "AH-8", "AHP-3 / acetylhexapeptide-3 (paper shorthand)", "Argireline\u2122 (Lipotec / Lubrizol trade name)", "Argireline\u00ae Amplified (next-gen franchise peptide \u2014 different sequence evolution, not classic AH-8)", "Argireline\u00ae YOUth (oil-soluble / LipoClear delivery line extension)", "Ac-EEMQRR-NH2", "Ac-Glu-Glu-Met-Gln-Arg-Arg-NH2", "Argireline Solution 10% (mass-market finished-product shorthand, e.g. The Ordinary)", "CAS 616204-22-9 (commonly listed for acetyl hexapeptide-8)" ], "type": "Peptide", "category": "Skin, hair & tissue remodeling", "goals_use_cases": [ "skin/hair", "anti-aging discussion", "expression-line / dynamic wrinkle reduction talk", "periorbital wrinkles (crow\u2019s feet)", "forehead lines and glabellar \u201c11s\u201d", "smile / nasolabial dynamic-line softing (secondary talk)", "cosmetic peptide routines", "non-injectable \u201cBotox alternative\u201d / \u201cBotox in a bottle\u201d marketing talk", "fine-line appearance and makeup-crease softing", "needle-averse maintenance between neuromodulator appointments (discussed, confounded)", "adjunct after botulinum toxin to \u201cextend\u201d freeze (pilot/medical-adjunct talk)", "DIY multi-peptide serum building", "minority gray-market meso / intradermal facial injection discussion" ], "delivery_methods": [ "topical" ], "discussion_popularity": "Medium", "reach": "Local", "misspellings_search_terms": [ "argireline", "Acetyl Hexapeptide-8", "Acetyl Hexapeptide-8 Amide", "Acetyl Hexapeptide-3 (legacy INCI / older literature naming \u2014 often treated as the same hexapeptide franchise)", "AH-8", "AHP-3 / acetylhexapeptide-3 (paper shorthand)", "skin/hair", "anti-aging discussion", "expression-line / dynamic wrinkle reduction talk", "periorbital wrinkles (crow\u2019s feet)", "forehead lines and glabellar \u201c11s\u201d", "smile / nasolabial dynamic-line softing (secondary talk)" ], "feel_search": [ "skin/hair", "anti-aging discussion", "expression-line / dynamic wrinkle reduction talk", "periorbital wrinkles (crow\u2019s feet)", "forehead lines and glabellar \u201c11s\u201d", "smile / nasolabial dynamic-line softing (secondary talk)" ], "summary": "Argireline is acetyl hexapeptide-8, a topical cosmetic peptide used in products aimed at softening expression lines.", "search_blob": "argireline argireline acetyl hexapeptide-8 argireline peptide acetyl hexapeptide-8 amide acetyl hexapeptide-3 (legacy inci / older literature naming \u2014 often treated as the same hexapeptide franchise) ah-8 ahp-3 / acetylhexapeptide-3 (paper shorthand) argireline\u2122 (lipotec / lubrizol trade name) argireline\u00ae amplified (next-gen franchise peptide \u2014 different sequence evolution, not classic ah-8) argireline\u00ae youth (oil-soluble / lipoclear delivery line extension) ac-eemqrr-nh2 ac-glu-glu-met-gln-arg-arg-nh2 argireline solution 10% (mass-market finished-product shorthand, e.g. the ordinary) cas 616204-22-9 (commonly listed for acetyl hexapeptide-8) argireline acetyl hexapeptide-8 acetyl hexapeptide-8 amide acetyl hexapeptide-3 (legacy inci / older literature naming \u2014 often treated as the same hexapeptide franchise) ah-8 ahp-3 / acetylhexapeptide-3 (paper shorthand) skin/hair anti-aging discussion expression-line / dynamic wrinkle reduction talk periorbital wrinkles (crow\u2019s feet) forehead lines and glabellar \u201c11s\u201d smile / nasolabial dynamic-line softing (secondary talk) skin/hair anti-aging discussion expression-line / dynamic wrinkle reduction talk periorbital wrinkles (crow\u2019s feet) forehead lines and glabellar \u201c11s\u201d smile / nasolabial dynamic-line softing (secondary talk) cosmetic peptide routines non-injectable \u201cbotox alternative\u201d / \u201cbotox in a bottle\u201d marketing talk fine-line appearance and makeup-crease softing needle-averse maintenance between neuromodulator appointments (discussed, confounded) adjunct after botulinum toxin to \u201cextend\u201d freeze (pilot/medical-adjunct talk) diy multi-peptide serum building minority gray-market meso / intradermal facial injection discussion skin/hair anti-aging discussion expression-line / dynamic wrinkle reduction talk periorbital wrinkles (crow\u2019s feet) forehead lines and glabellar \u201c11s\u201d smile / nasolabial dynamic-line softing (secondary talk) argireline is acetyl hexapeptide-8, a topical cosmetic peptide used in products aimed at softening expression lines. some users describe temporary smoothing or tightness, often with matrixyl. they explicitly say the effect does not match botox. argireline is a peptide people look up for skin. users often report less concealer-creasing and softer morning forehead lines more than a \u201cfrozen\u201d face. skin, hair & tissue remodeling peptide local local \u2014 a face serum, not a whole-body shot. local site pin topical", "legal_class": null }, { "id": 75, "slug": "matrixyl", "name": "Matrixyl (palmitoyl pentapeptide-4)", "aliases": [ "Palmitoyl pentapeptide-4", "Matrixyl 3000 adjacency", "Palmitoyl pentapeptide-3 (pre-2006 INCI)", "Pal-KTTKS", "Pal-Lys-Thr-Thr-Lys-Ser", "Matrixyl", "Matrixyl\u2122 (Sederma / Croda trade name \u2014 classic)", "Matrixyl 3000 (related brand line; different peptides)", "Matrixyl Synthe'6 / Synthe\u20196 (related brand line; palmitoyl tripeptide-38)", "Matrixyl Morphomics (related brand line; palmitoyl tripeptide-56 acetate)", "PPP-4", "Collagen pentapeptide (community shorthand)" ], "type": "Peptide", "category": "Skin, hair & tissue remodeling", "goals_use_cases": [ "skin/hair", "anti-aging discussion", "fine lines & wrinkles", "collagen / firmness talk", "texture & density narratives", "cosmetic matrix remodeling", "photoaging appearance", "periocular / crow's feet talk", "tech-neck / barcode lip-line cosmetic talk", "gentler alternative-to-retinoid narratives", "DIY serum booster culture" ], "delivery_methods": [ "topical" ], "discussion_popularity": "Medium", "reach": "Local", "misspellings_search_terms": [ "matrixyl", "Matrixyl (palmitoyl pentapeptide-4)", "matrixyl-(palmitoyl-pentapeptide-4)", "Palmitoyl pentapeptide-4", "Palmitoyl pentapeptide-3 (pre-2006 INCI)", "Pal-KTTKS", "skin/hair", "anti-aging discussion", "fine lines & wrinkles", "collagen / firmness talk", "texture & density narratives", "cosmetic matrix remodeling" ], "feel_search": [ "skin/hair", "anti-aging discussion", "fine lines & wrinkles", "collagen / firmness talk", "texture & density narratives", "cosmetic matrix remodeling" ], "summary": "Original Matrixyl is palmitoyl pentapeptide-4, a cosmetic peptide used for fine lines; Matrixyl-branded blends and finished serums can contain different ingredients.", "search_blob": "matrixyl (palmitoyl pentapeptide-4) matrixyl palmitoyl pentapeptide-4 matrixyl 3000 adjacency palmitoyl pentapeptide-3 (pre-2006 inci) pal-kttks pal-lys-thr-thr-lys-ser matrixyl matrixyl\u2122 (sederma / croda trade name \u2014 classic) matrixyl 3000 (related brand line; different peptides) matrixyl synthe'6 / synthe\u20196 (related brand line; palmitoyl tripeptide-38) matrixyl morphomics (related brand line; palmitoyl tripeptide-56 acetate) ppp-4 collagen pentapeptide (community shorthand) matrixyl matrixyl (palmitoyl pentapeptide-4) matrixyl-(palmitoyl-pentapeptide-4) palmitoyl pentapeptide-4 palmitoyl pentapeptide-3 (pre-2006 inci) pal-kttks skin/hair anti-aging discussion fine lines & wrinkles collagen / firmness talk texture & density narratives cosmetic matrix remodeling skin/hair anti-aging discussion fine lines & wrinkles collagen / firmness talk texture & density narratives cosmetic matrix remodeling photoaging appearance periocular / crow's feet talk tech-neck / barcode lip-line cosmetic talk gentler alternative-to-retinoid narratives diy serum booster culture skin/hair anti-aging discussion fine lines & wrinkles collagen / firmness talk texture & density narratives cosmetic matrix remodeling original matrixyl is palmitoyl pentapeptide-4, a cosmetic peptide used for fine lines; matrixyl-branded blends and finished serums can contain different ingredients. a finished serum may feel hydrating or irritating: the reviewed user developed flaky, painful dryness within days and stopped. that does not identify which ingredient caused the reaction. matrixyl (palmitoyl pentapeptide-4) is a peptide people look up for skin. improved skin roughness, wrinkle volume, and wrinkle depth vs vehicle. skin, hair & tissue remodeling peptide local local \u2014 a face/skin serum, not a whole-body shot. local site pin topical", "legal_class": null }, { "id": 76, "slug": "melanotan-i", "name": "Melanotan I", "aliases": [ "Afamelanotide", "Scenesse", "MT-1", "NDP-MSH", "MT1", "Melanotan-1", "Melanotan 1", "[Nle4,D-Phe7]-\u03b1-MSH", "CUV1647", "Melanotan-I" ], "type": "Peptide", "category": "Tanning & melanocortin", "goals_use_cases": [ "skin/hair", "photoprotection discussion", "tanning / pigmentation", "UV-assisted bronze with fewer central sides than MT-II", "aesthetic skin tone", "UV tolerance (clinical EPP context)", "vitiligo adjunct discussion (clinical implant + NB-UVB)", "fair-skin melanin-density research context" ], "delivery_methods": [ "implant (clinical)", "injection discussion" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "melanotan-i", "melanotan i", "melanotani", "Afamelanotide", "Scenesse", "MT-1", "skin/hair", "photoprotection discussion", "tanning / pigmentation", "uv-assisted bronze with fewer central sides than mt-ii", "aesthetic skin tone", "uv tolerance (clinical epp context)" ], "feel_search": [ "skin/hair", "photoprotection discussion", "tanning / pigmentation", "uv-assisted bronze with fewer central sides than mt-ii", "aesthetic skin tone", "uv tolerance (clinical epp context)" ], "summary": "Melanotan I (afamelanotide) is an alpha-MSH analog affecting pigmentation; the medical implant and gray-market tanning vials are different formulations.", "search_blob": "melanotan i melanotan-i afamelanotide scenesse mt-1 ndp-msh mt1 melanotan-1 melanotan 1 [nle4,d-phe7]-\u03b1-msh cuv1647 melanotan-i melanotan-i melanotan i melanotani afamelanotide scenesse mt-1 skin/hair photoprotection discussion tanning / pigmentation uv-assisted bronze with fewer central sides than mt-ii aesthetic skin tone uv tolerance (clinical epp context) skin/hair photoprotection discussion tanning / pigmentation uv-assisted bronze with fewer central sides than mt-ii aesthetic skin tone uv tolerance (clinical epp context) vitiligo adjunct discussion (clinical implant + nb-uvb) fair-skin melanin-density research context skin/hair photoprotection discussion tanning / pigmentation uv-assisted bronze with fewer central sides than mt-ii aesthetic skin tone uv tolerance (clinical epp context) melanotan i (afamelanotide) is an alpha-msh analog affecting pigmentation; the medical implant and gray-market tanning vials are different formulations. melanotan i is a peptide people look up for tanning. progressive uniform-ish bronze over weeks when paired with uv; freckles and moles often darken first and most. tanning & melanocortin peptide systemic systemic mc1r-preferring \u03b1-msh analog; the licensed product is an implant, while community reports describe unverified subq vials. systemic whole-body circulating", "legal_class": null }, { "id": 77, "slug": "tesofensine", "name": "Tesofensine", "aliases": [ "NS2330", "NS-2330", "NS 2330", "Tesofensine hydrochloride", "Tesofensine HCl", "Tesofensine citrate (research-salt discussions)", "phenyltropane triple reuptake inhibitor (class talk)" ], "type": "Non-peptide", "category": "Metabolic research compounds", "goals_use_cases": [ "fat loss", "appetite control", "appetite control / food-noise reduction", "weight management research", "metabolic research", "craving reduction (discussed)", "body composition / lean-preservation narratives", "oral non-GLP-1 fat-loss alternative (community)", "energy expenditure / resting EE talk (preclinical + early human)", "GLP-1 stack adjunct for residual hunger (community)", "focus / motivation side-effect framing (anecdote)", "hypothalamic obesity / Tesomet-adjacent discussion" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "tesofensine", "NS2330", "NS-2330", "NS 2330", "Tesofensine hydrochloride", "Tesofensine HCl", "dry mouth", "insomnia", "heart rate", "food noise", "morning", "0.5 mg", "BioFlow", "appetite", "focus" ], "feel_search": [ "dry mouth", "insomnia", "heart rate", "food noise", "morning", "0.5 mg", "BioFlow", "appetite", "focus" ], "summary": "Tesofensine is an oral compound, not a peptide, people look up for appetite. Appetite quiet and dry mouth show up fast; energy/HRV stories split (some Oura HRV up, some RHR +10).", "search_blob": "tesofensine tesofensine ns2330 ns-2330 ns 2330 tesofensine hydrochloride tesofensine hcl tesofensine citrate (research-salt discussions) phenyltropane triple reuptake inhibitor (class talk) tesofensine ns2330 ns-2330 ns 2330 tesofensine hydrochloride tesofensine hcl dry mouth insomnia heart rate food noise morning 0.5 mg bioflow appetite focus fat loss appetite control appetite control / food-noise reduction weight management research metabolic research craving reduction (discussed) body composition / lean-preservation narratives oral non-glp-1 fat-loss alternative (community) energy expenditure / resting ee talk (preclinical + early human) glp-1 stack adjunct for residual hunger (community) focus / motivation side-effect framing (anecdote) hypothalamic obesity / tesomet-adjacent discussion dry mouth insomnia heart rate food noise morning 0.5 mg bioflow appetite focus tesofensine is an oral compound, not a peptide, people look up for appetite. appetite quiet and dry mouth show up fast; energy/hrv stories split (some oura hrv up, some rhr +10). reports disagree on sleep: some describe prolonged wakefulness or repeated waking, while another says their sleep schedule improved. tesofensine is an oral compound, not a peptide, people look up for appetite. appetite quiet and dry mouth show up fast; energy/hrv stories split (some oura hrv up, some rhr +10). morning only. 0.5 mg is the number people compare. heart-rate climb is the watch-for. metabolic research compounds non-peptide systemic systemic \u2014 an oral monoamine reuptake inhibitor discussed for appetite, food reward and energy balance; not a local or site-specific injection. systemic whole-body circulating", "legal_class": null }, { "id": 78, "slug": "bam15", "name": "BAM15", "aliases": [ "mitochondrial uncoupler BAM15", "BAM-15", "BAM 15", "mitochondrial protonophore BAM15", "oxadiazolo-pyrazine uncoupler BAM15", "N5,N6-bis(2-fluorophenyl)[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine", "N5,N6-bis(2-fluorophenyl)-[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine", "CAS 210302-17-3", "\u201csafer DNP\u201d BAM15 (community nickname)" ], "type": "Non-peptide", "category": "Metabolic research compounds", "goals_use_cases": [ "fat loss", "metabolic health", "fat loss / energy-expenditure uncoupling", "body recomposition with lean-mass sparing (preclinical narrative)", "metabolic health / insulin sensitivity research (preclinical)", "fatty liver / hepatic steatosis narratives (preclinical)", "glucose tolerance / diabetes-adjacent models (animal)", "DNP-alternative discussion (\u201csafer uncoupler\u201d lore)", "sarcopenic obesity / aged-muscle protection (preclinical)", "anti-inflammatory / antioxidant liver talk (preclinical metabolomics)", "atherosclerosis / AMPK\u2013NLRP3 research adjacency (preclinical)", "GLP-1 add-on when appetite drugs stall (community theory)", "mitochondrial uncoupling research tool" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "bam15", "BAM-15", "BAM 15", "mitochondrial uncoupler BAM15", "mitochondrial protonophore BAM15", "oxadiazolo-pyrazine uncoupler BAM15", "safer DNP", "uncoupler", "heat", "night sweats", "SLU", "250mg", "inject", "thermogenic", "mitochondria" ], "feel_search": [ "safer DNP", "uncoupler", "heat", "night sweats", "SLU", "250mg", "inject", "thermogenic", "mitochondria" ], "summary": "BAM15 is a mitochondrial uncoupler discussed for fat loss, not a peptide or approved weight-loss medicine. No solid human RCT or approved label for weight loss as of research cut.", "search_blob": "bam15 bam15 mitochondrial uncoupler bam15 bam-15 bam 15 mitochondrial protonophore bam15 oxadiazolo-pyrazine uncoupler bam15 n5,n6-bis(2-fluorophenyl)[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine n5,n6-bis(2-fluorophenyl)-[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine cas 210302-17-3 \u201csafer dnp\u201d bam15 (community nickname) bam15 bam-15 bam 15 mitochondrial uncoupler bam15 mitochondrial protonophore bam15 oxadiazolo-pyrazine uncoupler bam15 safer dnp uncoupler heat night sweats slu 250mg inject thermogenic mitochondria fat loss metabolic health fat loss / energy-expenditure uncoupling body recomposition with lean-mass sparing (preclinical narrative) metabolic health / insulin sensitivity research (preclinical) fatty liver / hepatic steatosis narratives (preclinical) glucose tolerance / diabetes-adjacent models (animal) dnp-alternative discussion (\u201csafer uncoupler\u201d lore) sarcopenic obesity / aged-muscle protection (preclinical) anti-inflammatory / antioxidant liver talk (preclinical metabolomics) atherosclerosis / ampk\u2013nlrp3 research adjacency (preclinical) glp-1 add-on when appetite drugs stall (community theory) mitochondrial uncoupling research tool safer dnp uncoupler heat night sweats slu 250mg inject thermogenic mitochondria bam15 is a mitochondrial uncoupler discussed for fat loss, not a peptide or approved weight-loss medicine. no solid human rct or approved label for weight loss as of research cut. a combined bam15/sana log describes little at first, warmth near week one and later weight loss. hot weather and the second compound limit attribution. bam15 is a mitochondrial uncoupler discussed for fat loss, not a peptide or approved weight-loss medicine. no solid human rct or approved label for weight loss as of research cut. 2026 dose camps fight from a few mg to 250 mg caps and even gram-day posts. heat is an unreliable tell. metabolic research compounds non-peptide systemic systemic \u2014 an oral mitochondrial uncoupler in fat-loss discussion; mouse liver/adipose findings do not prove human safety or spot-fat effects. systemic whole-body circulating", "legal_class": null }, { "id": 79, "slug": "urolithin-a", "name": "Urolithin A", "aliases": [ "Mitopure-class discussion", "UA", "Uro-A", "UroA", "Mitopure", "Mitopure-class UA", "Timeline Mitopure", "3,8-Dihydroxy-urolithin", "3,8-dihydroxy-6H-dibenzo[b,d]pyran-6-one", "ellagitannin gut metabolite", "pomegranate postbiotic UA" ], "type": "Non-peptide", "category": "Longevity & cellular energy", "goals_use_cases": [ "longevity", "muscle", "mitochondrial discussion", "longevity / healthy aging", "mitophagy / mitochondrial recycling", "muscle strength (middle-age RCT talk)", "muscle endurance / fatigue resistance (older-adult RCT talk)", "endurance / aerobic capacity markers (VO2, 6-min walk)", "cellular energy without stimulant feel", "training recovery continuity", "inflammation biomarker discussion (CRP / cytokines)", "non-producer food-bypass strategy", "joint / osteoarthritis interest (mostly preclinical)", "topical skin aging (separate cream trials)", "immune-aging / immunosenescence research interest", "sports-nutrition adjunct discussion (emerging)", "stack companion to NAD precursors and autophagy agents" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "urolithin-a", "urolithin a", "urolithina", "UA", "Uro-A", "UroA", "energy", "recovery", "HRV", "mitopure", "fake", "heavy legs" ], "feel_search": [ "energy", "recovery", "HRV", "mitopure", "fake", "heavy legs" ], "summary": "Urolithin A is a gut-microbe-derived metabolite of compounds in foods such as pomegranate and walnuts, also sold as an oral supplement.", "search_blob": "urolithin a urolithin-a mitopure-class discussion ua uro-a uroa mitopure mitopure-class ua timeline mitopure 3,8-dihydroxy-urolithin 3,8-dihydroxy-6h-dibenzo[b,d]pyran-6-one ellagitannin gut metabolite pomegranate postbiotic ua urolithin-a urolithin a urolithina ua uro-a uroa energy recovery hrv mitopure fake heavy legs longevity muscle mitochondrial discussion longevity / healthy aging mitophagy / mitochondrial recycling muscle strength (middle-age rct talk) muscle endurance / fatigue resistance (older-adult rct talk) endurance / aerobic capacity markers (vo2, 6-min walk) cellular energy without stimulant feel training recovery continuity inflammation biomarker discussion (crp / cytokines) non-producer food-bypass strategy joint / osteoarthritis interest (mostly preclinical) topical skin aging (separate cream trials) immune-aging / immunosenescence research interest sports-nutrition adjunct discussion (emerging) stack companion to nad precursors and autophagy agents energy recovery hrv mitopure fake heavy legs urolithin a is a gut-microbe-derived metabolite of compounds in foods such as pomegranate and walnuts, also sold as an oral supplement. some users describe greater workout capacity or clearer energy; others report marked fatigue, and daily-life benefits are inconsistent. urolithin a is an oral compound for muscle. vendor and community checkpoint for subjective energy; mitophagy molecular signatures already reported by ~1 month in clinical work. 500 mg is the cheap/default chart; 1,000 mg is the endurance/immune trial chart. fake amazon bottles were a 2025\u201326 scandal. longevity & cellular energy non-peptide systemic systemic oral postbiotic for whole-body mitophagy and muscle/mitochondrial endpoints \u2014 not a local inject and not a classical stimulant. systemic whole-body circulating", "legal_class": null }, { "id": 80, "slug": "spermidine", "name": "Spermidine", "aliases": [ "dietary spermidine", "polyamine longevity discussion", "spermidine trihydrochloride", "spermidine 3HCl / 3HCL", "hpSPD (high-purity spermidine)", "wheat-germ spermidine extract", "CelVio\u00ae / spermidineLIFE-type extract", "N-(3-aminopropyl)butane-1,4-diamine", "polyamine (putrescine \u2192 spermidine \u2192 spermine axis)" ], "type": "Non-peptide", "category": "Longevity & cellular energy", "goals_use_cases": [ "longevity", "autophagy discussion", "longevity / healthy aging", "autophagy / cellular cleanup narratives", "caloric-restriction / fasting mimetic talk", "cognition / memory in older adults (mixed trials)", "cardiometabolic / cardiac remodeling interest (preclinical + POLYCAD)", "immune aging / T-cell autophagy discussion", "hair anagen / follicle talk (sparse human supplement data)", "skin / \u201ccellular renewal\u201d marketing", "food-first polyamine intake optimization", "stack companion to NMN/NR, resveratrol, rapamycin, fisetin" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "spermidine", "dietary spermidine", "polyamine longevity discussion", "spermidine trihydrochloride", "spermidine 3HCl / 3HCL", "hpSPD (high-purity spermidine)", "longevity / healthy aging", "autophagy / cellular cleanup narratives", "caloric-restriction / fasting mimetic talk", "cognition / memory in older adults (mixed trials)", "cardiometabolic / cardiac remodeling interest (preclinical + polycad)", "immune aging / t-cell autophagy discussion" ], "feel_search": [ "longevity / healthy aging", "autophagy / cellular cleanup narratives", "caloric-restriction / fasting mimetic talk", "cognition / memory in older adults (mixed trials)", "cardiometabolic / cardiac remodeling interest (preclinical + polycad)", "immune aging / t-cell autophagy discussion" ], "summary": "Spermidine is a naturally occurring polyamine found in foods and sold as extracts or purified salts for longevity-related interests.", "search_blob": "spermidine spermidine dietary spermidine polyamine longevity discussion spermidine trihydrochloride spermidine 3hcl / 3hcl hpspd (high-purity spermidine) wheat-germ spermidine extract celvio\u00ae / spermidinelife-type extract n-(3-aminopropyl)butane-1,4-diamine polyamine (putrescine \u2192 spermidine \u2192 spermine axis) spermidine dietary spermidine polyamine longevity discussion spermidine trihydrochloride spermidine 3hcl / 3hcl hpspd (high-purity spermidine) longevity / healthy aging autophagy / cellular cleanup narratives caloric-restriction / fasting mimetic talk cognition / memory in older adults (mixed trials) cardiometabolic / cardiac remodeling interest (preclinical + polycad) immune aging / t-cell autophagy discussion longevity autophagy discussion longevity / healthy aging autophagy / cellular cleanup narratives caloric-restriction / fasting mimetic talk cognition / memory in older adults (mixed trials) cardiometabolic / cardiac remodeling interest (preclinical + polycad) immune aging / t-cell autophagy discussion hair anagen / follicle talk (sparse human supplement data) skin / \u201ccellular renewal\u201d marketing food-first polyamine intake optimization stack companion to nmn/nr, resveratrol, rapamycin, fisetin longevity / healthy aging autophagy / cellular cleanup narratives caloric-restriction / fasting mimetic talk cognition / memory in older adults (mixed trials) cardiometabolic / cardiac remodeling interest (preclinical + polycad) immune aging / t-cell autophagy discussion spermidine is a naturally occurring polyamine found in foods and sold as extracts or purified salts for longevity-related interests. one user noticed no benefit, while another described body heat and disturbed sleep with a different brand. spermidine is an oral compound people look up for longevity. improved mnemonic discrimination (mst) vs control in a small sample; often cited as the \u201cmemory works\u201d study. longevity & cellular energy non-peptide systemic systemic oral polyamine already present in tissues and diet; marketed as body-wide autophagy/aging support, not a single-organ drug or injectable peptide. systemic whole-body circulating", "legal_class": null }, { "id": 81, "slug": "fisetin", "name": "Fisetin", "aliases": [ "3,3',4',7-tetrahydroxyflavone", "3,3\u2032,4\u2032,7-Tetrahydroxyflavone", "Fisetin flavonoid", "Natural fisetin", "Senolytic fisetin (discussion label)", "Novusetin (branded ~95% fisetin extract, often Rhus-derived)", "Cognisetin (marketing / memory-branded fisetin label)", "FF-20 / hybrid-hydrogel fisetin (enhanced-bioavailability research form)" ], "type": "Non-peptide", "category": "Senolytic & longevity compounds", "goals_use_cases": [ "longevity", "senolytic discussion", "longevity / healthspan", "senolytic / zombie-cell clearance discussion", "healthy aging / frailty and physical function interest", "inflammation / SASP-burden narratives", "cellular senescence markers (research endpoints)", "cognitive aging / neuroprotection interest (mostly preclinical + minority user logs)", "antioxidant / polyphenol stack interest", "metabolic aging and diabetes-adjacent inflammation talk (preclinical + trial interest)", "allergy / mast-cell / nasal inflammation crossover (anecdotal + older mouse work)", "vs D+Q natural single-agent alternative" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "fisetin", "3,3',4',7-tetrahydroxyflavone", "3,3\u2032,4\u2032,7-Tetrahydroxyflavone", "Fisetin flavonoid", "Natural fisetin", "Senolytic fisetin (discussion label)", "longevity / healthspan", "senolytic / zombie-cell clearance discussion", "healthy aging / frailty and physical function interest", "inflammation / sasp-burden narratives", "cellular senescence markers (research endpoints)", "cognitive aging / neuroprotection interest (mostly preclinical + minority user logs)" ], "feel_search": [ "longevity / healthspan", "senolytic / zombie-cell clearance discussion", "healthy aging / frailty and physical function interest", "inflammation / sasp-burden narratives", "cellular senescence markers (research endpoints)", "cognitive aging / neuroprotection interest (mostly preclinical + minority user logs)" ], "summary": "Fisetin is a plant flavonol sold as a supplement and studied experimentally for effects on senescent cells and aging biology.", "search_blob": "fisetin fisetin 3,3',4',7-tetrahydroxyflavone 3,3\u2032,4\u2032,7-tetrahydroxyflavone fisetin flavonoid natural fisetin senolytic fisetin (discussion label) novusetin (branded ~95% fisetin extract, often rhus-derived) cognisetin (marketing / memory-branded fisetin label) ff-20 / hybrid-hydrogel fisetin (enhanced-bioavailability research form) fisetin 3,3',4',7-tetrahydroxyflavone 3,3\u2032,4\u2032,7-tetrahydroxyflavone fisetin flavonoid natural fisetin senolytic fisetin (discussion label) longevity / healthspan senolytic / zombie-cell clearance discussion healthy aging / frailty and physical function interest inflammation / sasp-burden narratives cellular senescence markers (research endpoints) cognitive aging / neuroprotection interest (mostly preclinical + minority user logs) longevity senolytic discussion longevity / healthspan senolytic / zombie-cell clearance discussion healthy aging / frailty and physical function interest inflammation / sasp-burden narratives cellular senescence markers (research endpoints) cognitive aging / neuroprotection interest (mostly preclinical + minority user logs) antioxidant / polyphenol stack interest metabolic aging and diabetes-adjacent inflammation talk (preclinical + trial interest) allergy / mast-cell / nasal inflammation crossover (anecdotal + older mouse work) vs d+q natural single-agent alternative longevity / healthspan senolytic / zombie-cell clearance discussion healthy aging / frailty and physical function interest inflammation / sasp-burden narratives cellular senescence markers (research endpoints) cognitive aging / neuroprotection interest (mostly preclinical + minority user logs) fisetin is a plant flavonol sold as a supplement and studied experimentally for effects on senescent cells and aging biology. one multi-ingredient senolytic account describes profound fatigue within eight hours lasting days, while acknowledging possible illness. that is not proof of cell clearance. fisetin is a compound. main \u201cdid anything change?\u201d window\u2014subtle joint, sinus, energy, or recovery shifts if claimed; also the window some describe mild fatigue or feverishness. senolytic & longevity compounds non-peptide systemic systemic oral flavonoid for whole-body senescent-cell, sasp, and aging-inflammation talk\u2014not a local injury inject, peptide, or tissue-targeted therapy. systemic whole-body circulating", "legal_class": null }, { "id": 82, "slug": "quercetin", "name": "Quercetin", "aliases": [ "quercetin phytosome discussion", "Quercetin dihydrate", "Quercetin aglycone", "Quercetin phytosome", "Quercetin Phytosome\u2122", "Quercefit", "QuerceFit\u00ae", "EMIQ", "Enzymatically modified isoquercitrin", "Isoquercetin", "3,3\u2032,4\u2032,5,7-pentahydroxyflavone", "SOPHORIN (historical plant-flavonoid context)", "D+Q (with dasatinib)" ], "type": "Non-peptide", "category": "Senolytic & longevity compounds", "goals_use_cases": [ "longevity", "immune", "senolytic stack discussion", "inflammation (discussed)", "allergy / seasonal comfort (discussed)", "mast-cell / histamine talk", "antioxidant support (discussed)", "metabolic markers (discussed)", "uric acid / gout-adjacent discussion", "recovery continuity", "upper-respiratory season stacks (community)", "zinc ionophore narrative (community)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "quercetin", "Quercetin dihydrate", "Quercetin aglycone", "Quercetin phytosome", "Quercetin Phytosome\u2122", "Quercefit", "longevity", "immune", "senolytic stack discussion", "inflammation (discussed)", "allergy / seasonal comfort (discussed)", "mast-cell / histamine talk" ], "feel_search": [ "longevity", "immune", "senolytic stack discussion", "inflammation (discussed)", "allergy / seasonal comfort (discussed)", "mast-cell / histamine talk" ], "summary": "Quercetin is a plant flavonol sold as an oral supplement and discussed for allergy, mast-cell and longevity-related interests.", "search_blob": "quercetin quercetin quercetin phytosome discussion quercetin dihydrate quercetin aglycone quercetin phytosome quercetin phytosome\u2122 quercefit quercefit\u00ae emiq enzymatically modified isoquercitrin isoquercetin 3,3\u2032,4\u2032,5,7-pentahydroxyflavone sophorin (historical plant-flavonoid context) d+q (with dasatinib) quercetin quercetin dihydrate quercetin aglycone quercetin phytosome quercetin phytosome\u2122 quercefit longevity immune senolytic stack discussion inflammation (discussed) allergy / seasonal comfort (discussed) mast-cell / histamine talk longevity immune senolytic stack discussion inflammation (discussed) allergy / seasonal comfort (discussed) mast-cell / histamine talk antioxidant support (discussed) metabolic markers (discussed) uric acid / gout-adjacent discussion recovery continuity upper-respiratory season stacks (community) zinc ionophore narrative (community) longevity immune senolytic stack discussion inflammation (discussed) allergy / seasonal comfort (discussed) mast-cell / histamine talk quercetin is a plant flavonol sold as an oral supplement and discussed for allergy, mast-cell and longevity-related interests. some posters describe feeling better, while others report headaches, gi upset or worse symptoms; the responses are sharply mixed. quercetin is an oral supplement people look up for longevity. easier training weeks, less \u201cinflamed\u201d feel on daily use \u2014 confounded and subjective. senolytic & longevity compounds non-peptide systemic systemic oral flavonol used in supplement and d+q discussions; food, aglycone, glycoside and enhanced-absorption forms are not equivalent. systemic whole-body circulating", "legal_class": null }, { "id": 83, "slug": "dasatinib", "name": "Dasatinib", "aliases": [ "Sprycel", "D+Q senolytic pair discussion", "BMS-354825", "Phyrago (dasatinib tablets brand discussed in PK notes)", "D+Q (with quercetin)", "DQ / D&Q senolytic pair", "Dasatinib + quercetin senolytic pair", "Intermittent dasatinib (senolytic pulse talk)" ], "type": "Non-peptide", "category": "Senolytic & longevity compounds", "goals_use_cases": [ "longevity", "senolytic discussion", "longevity / geroscience discussion", "senolytic / senescent-cell clearance discussion", "cellular senescence and SASP burden (research)", "frailty / physical function (discussed in IPF and aging pilots)", "age-related tissue burden (adipose, bone, disc \u2014 research)", "IPF / fibrotic disease research contexts", "diabetic kidney disease / CKD aging pilots", "postmenopausal bone metabolism (phase 2)", "cognitive aging / MCI\u2013AD early trials (SToMP-AD family)", "metabolic / obesity / fatty-liver aging interest (preclinical + listed trials)", "stem-cell transplant / premature-aging survivor research interest", "not primary: continuous CML/Ph+ ALL oncology use (labeled indication; different regimen)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "dasatinib", "Sprycel", "BMS-354825", "Phyrago (dasatinib tablets brand discussed in PK notes)", "D+Q (with quercetin)", "DQ / D&Q senolytic pair", "longevity / geroscience discussion", "senolytic / senescent-cell clearance discussion", "cellular senescence and sasp burden (research)", "frailty / physical function (discussed in ipf and aging pilots)", "age-related tissue burden (adipose, bone, disc \u2014 research)", "ipf / fibrotic disease research contexts" ], "feel_search": [ "longevity / geroscience discussion", "senolytic / senescent-cell clearance discussion", "cellular senescence and sasp burden (research)", "frailty / physical function (discussed in ipf and aging pilots)", "age-related tissue burden (adipose, bone, disc \u2014 research)", "ipf / fibrotic disease research contexts" ], "summary": "Dasatinib (Sprycel) is a prescription tyrosine-kinase inhibitor for certain leukemias, also studied with quercetin in experimental senolytic research.", "search_blob": "dasatinib dasatinib sprycel d+q senolytic pair discussion bms-354825 phyrago (dasatinib tablets brand discussed in pk notes) d+q (with quercetin) dq / d&q senolytic pair dasatinib + quercetin senolytic pair intermittent dasatinib (senolytic pulse talk) dasatinib sprycel bms-354825 phyrago (dasatinib tablets brand discussed in pk notes) d+q (with quercetin) dq / d&q senolytic pair longevity / geroscience discussion senolytic / senescent-cell clearance discussion cellular senescence and sasp burden (research) frailty / physical function (discussed in ipf and aging pilots) age-related tissue burden (adipose, bone, disc \u2014 research) ipf / fibrotic disease research contexts longevity senolytic discussion longevity / geroscience discussion senolytic / senescent-cell clearance discussion cellular senescence and sasp burden (research) frailty / physical function (discussed in ipf and aging pilots) age-related tissue burden (adipose, bone, disc \u2014 research) ipf / fibrotic disease research contexts diabetic kidney disease / ckd aging pilots postmenopausal bone metabolism (phase 2) cognitive aging / mci\u2013ad early trials (stomp-ad family) metabolic / obesity / fatty-liver aging interest (preclinical + listed trials) stem-cell transplant / premature-aging survivor research interest not primary: continuous cml/ph+ all oncology use (labeled indication; different regimen) longevity / geroscience discussion senolytic / senescent-cell clearance discussion cellular senescence and sasp burden (research) frailty / physical function (discussed in ipf and aging pilots) age-related tissue burden (adipose, bone, disc \u2014 research) ipf / fibrotic disease research contexts dasatinib (sprycel) is a prescription tyrosine-kinase inhibitor for certain leukemias, also studied with quercetin in experimental senolytic research. d+q users report both no noticeable change and improvements while also using rapamycin and other agents. those accounts cannot isolate dasatinib or prove senescent-cell clearance. dasatinib is an oral compound for longevity. no large rct proving healthy-adult healthspan or lifespan benefit; intermittent \u2260 proven risk-free. senolytic & longevity compounds non-peptide systemic systemic oral multi-kinase (bcr-abl / src-family) small molecule. systemic whole-body circulating", "legal_class": null }, { "id": 84, "slug": "ca-akg", "name": "Ca-AKG", "aliases": [ "Calcium alpha-ketoglutarate", "AKG", "Calcium \u03b1-ketoglutarate", "CaAKG", "Ca AKG", "Calcium aKG", "AKG (calcium salt form)", "dAKG (delayed-release CaAKG, product framing)", "LifeAKG\u2122 (Rejuvant / timed-release ingredient branding)", "Calcium alpha-ketoglutarate monohydrate", "AKG-Ca / Ca-aKG (literature variants)" ], "type": "Non-peptide", "category": "Longevity & cellular energy", "goals_use_cases": [ "longevity", "metabolic health", "longevity / healthspan", "biological age / DNA-methylation clock interest", "metabolic health / TCA-cycle support (discussed)", "cellular energy narratives", "inflammation / inflammaging talk (animal-driven)", "frailty compression narratives (mouse)", "bone / osteopenia context (older high-dose human work)", "muscle / sarcopenia interest (secondary endpoints, animal atrophy models)", "hemodialysis / nitrogen-balance historical clinical use", "multi-ingredient longevity formulas (e.g., NOVOS-style, Rejuvant-style)", "stack companion to NMN/NR and other aging compounds", "vs AAKG sport products \u2014 longevity users prefer calcium salt" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "ca-akg", "ca akg", "caakg", "Calcium alpha-ketoglutarate", "Calcium \u03b1-ketoglutarate", "Calcium aKG", "longevity / healthspan", "biological age / dna-methylation clock interest", "metabolic health / tca-cycle support (discussed)", "cellular energy narratives", "inflammation / inflammaging talk (animal-driven)", "frailty compression narratives (mouse)" ], "feel_search": [ "longevity / healthspan", "biological age / dna-methylation clock interest", "metabolic health / tca-cycle support (discussed)", "cellular energy narratives", "inflammation / inflammaging talk (animal-driven)", "frailty compression narratives (mouse)" ], "summary": "Calcium alpha-ketoglutarate (Ca-AKG) is a calcium salt of an energy-metabolism compound, sold for longevity and exercise interest.", "search_blob": "ca-akg ca-akg calcium alpha-ketoglutarate akg calcium \u03b1-ketoglutarate caakg ca akg calcium akg akg (calcium salt form) dakg (delayed-release caakg, product framing) lifeakg\u2122 (rejuvant / timed-release ingredient branding) calcium alpha-ketoglutarate monohydrate akg-ca / ca-akg (literature variants) ca-akg ca akg caakg calcium alpha-ketoglutarate calcium \u03b1-ketoglutarate calcium akg longevity / healthspan biological age / dna-methylation clock interest metabolic health / tca-cycle support (discussed) cellular energy narratives inflammation / inflammaging talk (animal-driven) frailty compression narratives (mouse) longevity metabolic health longevity / healthspan biological age / dna-methylation clock interest metabolic health / tca-cycle support (discussed) cellular energy narratives inflammation / inflammaging talk (animal-driven) frailty compression narratives (mouse) bone / osteopenia context (older high-dose human work) muscle / sarcopenia interest (secondary endpoints, animal atrophy models) hemodialysis / nitrogen-balance historical clinical use multi-ingredient longevity formulas (e.g., novos-style, rejuvant-style) stack companion to nmn/nr and other aging compounds vs aakg sport products \u2014 longevity users prefer calcium salt longevity / healthspan biological age / dna-methylation clock interest metabolic health / tca-cycle support (discussed) cellular energy narratives inflammation / inflammaging talk (animal-driven) frailty compression narratives (mouse) calcium alpha-ketoglutarate (ca-akg) is a calcium salt of an energy-metabolism compound, sold for longevity and exercise interest. a ca-akg user describes subtle running benefits across continued use, while other akg users report none. reports using other salts are not calcium-form evidence. calcium alpha-ketoglutarate is an oral compound people look up for longevity. little subjective \u201con\u201d signal is normal. longevity & cellular energy non-peptide systemic systemic \u2014 oral ca-akg is discussed for whole-body metabolic, inflammatory, epigenetic-clock, and longevity support, not local tissue targeting. systemic whole-body circulating", "legal_class": null }, { "id": 85, "slug": "glutathione", "name": "Glutathione", "aliases": [ "GSH", "L-glutathione", "liposomal glutathione", "reduced glutathione", "S-acetyl glutathione (SAG)", "\u03b3-L-glutamyl-L-cysteinylglycine", "Setria glutathione (branded oral form discussions)", "oxidized glutathione (GSSG)" ], "type": "Peptide", "category": "Antioxidant & detox discussion", "goals_use_cases": [ "skin/hair", "detox discussion", "immune", "recovery", "skin lightening / melasma / pigmentation (discussed)", "detox / liver support discussion", "immune / NK-cell adjacency", "oxidative stress / redox balance", "recovery / athletic \u201cglow\u201d talk", "longevity / master-antioxidant narratives", "Parkinson\u2019s IV and intranasal research adjacency", "fatty-liver / metabolic discussion", "IV med-spa wellness menus" ], "delivery_methods": [ "IV", "oral", "nebulized (discussed)", "sublingual" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "glutathione", "GSH", "L-glutathione", "reduced glutathione", "liposomal glutathione", "S-acetyl glutathione (SAG)", "skin lightening / melasma / pigmentation (discussed)", "detox / liver support discussion", "immune / nk-cell adjacency", "oxidative stress / redox balance", "recovery / athletic \u201cglow\u201d talk", "longevity / master-antioxidant narratives" ], "feel_search": [ "skin lightening / melasma / pigmentation (discussed)", "detox / liver support discussion", "immune / nk-cell adjacency", "oxidative stress / redox balance", "recovery / athletic \u201cglow\u201d talk", "longevity / master-antioxidant narratives" ], "summary": "Glutathione is a small antioxidant peptide; people discuss oral products and injections for skin changes, recovery and perceived energy.", "search_blob": "glutathione glutathione gsh l-glutathione liposomal glutathione reduced glutathione s-acetyl glutathione (sag) \u03b3-l-glutamyl-l-cysteinylglycine setria glutathione (branded oral form discussions) oxidized glutathione (gssg) glutathione gsh l-glutathione reduced glutathione liposomal glutathione s-acetyl glutathione (sag) skin lightening / melasma / pigmentation (discussed) detox / liver support discussion immune / nk-cell adjacency oxidative stress / redox balance recovery / athletic \u201cglow\u201d talk longevity / master-antioxidant narratives skin/hair detox discussion immune recovery skin lightening / melasma / pigmentation (discussed) detox / liver support discussion immune / nk-cell adjacency oxidative stress / redox balance recovery / athletic \u201cglow\u201d talk longevity / master-antioxidant narratives parkinson\u2019s iv and intranasal research adjacency fatty-liver / metabolic discussion iv med-spa wellness menus skin lightening / melasma / pigmentation (discussed) detox / liver support discussion immune / nk-cell adjacency oxidative stress / redox balance recovery / athletic \u201cglow\u201d talk longevity / master-antioxidant narratives glutathione is a small antioxidant peptide; people discuss oral products and injections for skin changes, recovery and perceived energy. oral users often notice little, or gi discomfort. iv reports include brief warmth, an unusual taste or flushing; energy and skin claims develop inconsistently and depend on the formulation. glutathione is an oral compound people look up for skin. melasma/lightening rcts and clinic talk track color/masi over ~4\u201312 weeks, not overnight. antioxidant & detox discussion peptide systemic mostly systemic\u2014oral, liposomal and iv use dominate antioxidant, liver and skin talk; topical, airway and intranasal contexts remain route-specific. systemic whole-body circulating", "legal_class": null }, { "id": 86, "slug": "nac", "name": "NAC", "aliases": [ "N-acetylcysteine", "N-acetyl-L-cysteine", "N-acetyl cysteine", "Acetylcysteine", "Acetadote (IV brand discussions)", "Mucomyst (historical mucolytic / oral antidote brand talk)", "NALC", "GlyNAC (glycine + NAC stack name)", "N-AcCys" ], "type": "Non-peptide", "category": "Antioxidant & detox discussion", "goals_use_cases": [ "skin", "respiratory discussion", "detox discussion", "mental health adjacency", "liver support discussion", "respiratory / mucolytic discussion", "COPD / chronic bronchitis exacerbation talk", "bronchiectasis mucus-clearance talk", "liver support / post-alcohol detox discussion", "acetaminophen-overdose antidote (clinical framing only)", "glutathione / antioxidant support", "OCD / compulsion adjunct discussion", "BFRB (trichotillomania, skin-picking/excoriation, nail-biting)", "addiction / craving recovery adjacency (cannabis, nicotine, cocaine, alcohol, gambling pilots)", "mental health adjacency (schizophrenia negative symptoms, bipolar, autism irritability adjunct talk)", "male fertility / sperm-quality discussion", "immune / infection recovery talk", "longevity / aging-redox narratives (GlyNAC)", "hangover-product adjacency (regulatory / marketing history)", "athletic recovery / training-adjacent antioxidant talk (mixed, dose-dependent)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "nac", "N-acetylcysteine", "N-acetyl-L-cysteine", "N-acetyl cysteine", "Acetylcysteine", "Acetadote (IV brand discussions)", "respiratory / mucolytic discussion", "copd / chronic bronchitis exacerbation talk", "bronchiectasis mucus-clearance talk", "liver support / post-alcohol detox discussion", "acetaminophen-overdose antidote (clinical framing only)", "glutathione / antioxidant support" ], "feel_search": [ "respiratory / mucolytic discussion", "copd / chronic bronchitis exacerbation talk", "bronchiectasis mucus-clearance talk", "liver support / post-alcohol detox discussion", "acetaminophen-overdose antidote (clinical framing only)", "glutathione / antioxidant support" ], "summary": "NAC is N-acetylcysteine, a cysteine derivative used medically for mucus and acetaminophen poisoning, and as a supplement for other goals.", "search_blob": "nac nac n-acetylcysteine n-acetyl-l-cysteine n-acetyl cysteine acetylcysteine acetadote (iv brand discussions) mucomyst (historical mucolytic / oral antidote brand talk) nalc glynac (glycine + nac stack name) n-accys nac n-acetylcysteine n-acetyl-l-cysteine n-acetyl cysteine acetylcysteine acetadote (iv brand discussions) respiratory / mucolytic discussion copd / chronic bronchitis exacerbation talk bronchiectasis mucus-clearance talk liver support / post-alcohol detox discussion acetaminophen-overdose antidote (clinical framing only) glutathione / antioxidant support skin respiratory discussion detox discussion mental health adjacency liver support discussion respiratory / mucolytic discussion copd / chronic bronchitis exacerbation talk bronchiectasis mucus-clearance talk liver support / post-alcohol detox discussion acetaminophen-overdose antidote (clinical framing only) glutathione / antioxidant support ocd / compulsion adjunct discussion bfrb (trichotillomania, skin-picking/excoriation, nail-biting) addiction / craving recovery adjacency (cannabis, nicotine, cocaine, alcohol, gambling pilots) mental health adjacency (schizophrenia negative symptoms, bipolar, autism irritability adjunct talk) male fertility / sperm-quality discussion immune / infection recovery talk longevity / aging-redox narratives (glynac) hangover-product adjacency (regulatory / marketing history) athletic recovery / training-adjacent antioxidant talk (mixed, dose-dependent) respiratory / mucolytic discussion copd / chronic bronchitis exacerbation talk bronchiectasis mucus-clearance talk liver support / post-alcohol detox discussion acetaminophen-overdose antidote (clinical framing only) glutathione / antioxidant support nac is n-acetylcysteine, a cysteine derivative used medically for mucus and acetaminophen poisoning, and as a supplement for other goals. some notice easier mucus clearance; mood and intrusive-thought reports vary from marked calm to nothing. sulfur taste, nausea or stomach discomfort can appear early. nac is an oral compound people look up for cough. easier productive cough and less \u201cstuck\u201d sputum. antioxidant & detox discussion non-peptide systemic systemic oral/iv cysteine donor; glutathione and system xc\u2212 talk. inhaled nac is more airway-local; topical use is local. systemic whole-body circulating", "legal_class": null }, { "id": 87, "slug": "ldn", "name": "Low-Dose Naltrexone (LDN)", "aliases": [ "LDN", "naltrexone low dose", "low dose naltrexone", "low-dose naltrexone", "ultra-low-dose naltrexone (ULDN)", "very low-dose naltrexone (VLDN)", "naltrexone (low-dose / compounding)", "4.5 mg naltrexone", "Bihari protocol naltrexone (historical LDN framing)" ], "type": "Non-peptide", "category": "Immune & inflammation adjacents", "goals_use_cases": [ "immune", "inflammation discussion", "pain discussion", "mood", "fibromyalgia discussion", "autoimmune discussion", "chronic fatigue discussion", "ME/CFS discussion", "Long COVID discussion", "sleep quality discussion", "gut inflammation / Crohn\u2019s discussion", "multiple sclerosis symptom discussion", "Hashimoto\u2019s / thyroid autoimmunity discussion", "CRPS / centralized pain discussion", "MCAS / allergy adjacency talk" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "ldn", "Low-Dose Naltrexone (LDN)", "low-dose-naltrexone-(ldn)", "naltrexone low dose", "low dose naltrexone", "low-dose naltrexone", "immune", "inflammation discussion", "pain discussion", "mood", "fibromyalgia discussion", "autoimmune discussion" ], "feel_search": [ "immune", "inflammation discussion", "pain discussion", "mood", "fibromyalgia discussion", "autoimmune discussion" ], "summary": "LDN means low-dose naltrexone, an opioid-receptor blocker used off label in much smaller amounts than standard addiction-treatment doses.", "search_blob": "low-dose naltrexone (ldn) ldn ldn naltrexone low dose low dose naltrexone low-dose naltrexone ultra-low-dose naltrexone (uldn) very low-dose naltrexone (vldn) naltrexone (low-dose / compounding) 4.5 mg naltrexone bihari protocol naltrexone (historical ldn framing) ldn low-dose naltrexone (ldn) low-dose-naltrexone-(ldn) naltrexone low dose low dose naltrexone low-dose naltrexone immune inflammation discussion pain discussion mood fibromyalgia discussion autoimmune discussion immune inflammation discussion pain discussion mood fibromyalgia discussion autoimmune discussion chronic fatigue discussion me/cfs discussion long covid discussion sleep quality discussion gut inflammation / crohn\u2019s discussion multiple sclerosis symptom discussion hashimoto\u2019s / thyroid autoimmunity discussion crps / centralized pain discussion mcas / allergy adjacency talk immune inflammation discussion pain discussion mood fibromyalgia discussion autoimmune discussion ldn means low-dose naltrexone, an opioid-receptor blocker used off label in much smaller amounts than standard addiction-treatment doses. early sleep effects vary from vivid dreams to insomnia, sometimes lasting beyond the first week. some report less aching later; others feel only side effects or stop because the tradeoff is poor. low-dose naltrexone (ldn) is an oral compound people look up for immune support. subtle ache or \u201cinflammation noise\u201d drop for some; others still only sides. immune & inflammation adjacents non-peptide systemic systemic oral immune / neuroimmune modulator\u2014not a local injection target. systemic whole-body circulating", "legal_class": null }, { "id": 88, "slug": "nr", "name": "NR (Nicotinamide Riboside)", "aliases": [ "Niagen-class discussion", "nicotinamide riboside", "Nicotinamide riboside", "Nicotinamide riboside chloride", "NR chloride", "NRCl", "Niagen", "Niagen NR", "Tru Niagen", "Vitamin B3 riboside form", "NRPT (NR + pterostilbene blend; Basis-class)", "Nicotinamide ribose (common misspelling)" ], "type": "Non-peptide", "category": "Longevity & cellular energy", "goals_use_cases": [ "longevity", "energy", "metabolic health", "longevity / healthy aging foundation", "cellular NAD+ support", "daytime energy / resilience (discussed)", "metabolic health (explored; mixed trials)", "mitochondrial / cellular energy narrative", "cognition / brain aging (exploratory)", "recovery after stress or training (discussed)", "Parkinson\u2019s / neuro research interest", "long-COVID / fatigue research interest", "anti-inflammatory NAD-metabolome framing" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "nr", "NR (Nicotinamide Riboside)", "nr-(nicotinamide-riboside)", "Nicotinamide riboside", "Nicotinamide riboside chloride", "NR chloride", "longevity / healthy aging foundation", "cellular nad+ support", "daytime energy / resilience (discussed)", "metabolic health (explored; mixed trials)", "mitochondrial / cellular energy narrative", "cognition / brain aging (exploratory)" ], "feel_search": [ "longevity / healthy aging foundation", "cellular nad+ support", "daytime energy / resilience (discussed)", "metabolic health (explored; mixed trials)", "mitochondrial / cellular energy narrative", "cognition / brain aging (exploratory)" ], "summary": "NR is nicotinamide riboside, a vitamin B3 form sold as an oral NAD+ precursor for energy and healthy aging.", "search_blob": "nr (nicotinamide riboside) nr niagen-class discussion nicotinamide riboside nicotinamide riboside nicotinamide riboside chloride nr chloride nrcl niagen niagen nr tru niagen vitamin b3 riboside form nrpt (nr + pterostilbene blend; basis-class) nicotinamide ribose (common misspelling) nr nr (nicotinamide riboside) nr-(nicotinamide-riboside) nicotinamide riboside nicotinamide riboside chloride nr chloride longevity / healthy aging foundation cellular nad+ support daytime energy / resilience (discussed) metabolic health (explored; mixed trials) mitochondrial / cellular energy narrative cognition / brain aging (exploratory) longevity energy metabolic health longevity / healthy aging foundation cellular nad+ support daytime energy / resilience (discussed) metabolic health (explored; mixed trials) mitochondrial / cellular energy narrative cognition / brain aging (exploratory) recovery after stress or training (discussed) parkinson\u2019s / neuro research interest long-covid / fatigue research interest anti-inflammatory nad-metabolome framing longevity / healthy aging foundation cellular nad+ support daytime energy / resilience (discussed) metabolic health (explored; mixed trials) mitochondrial / cellular energy narrative cognition / brain aging (exploratory) nr is nicotinamide riboside, a vitamin b3 form sold as an oral nad+ precursor for energy and healthy aging. many describe no acute effect; others report subtle energy or less fatigue, while some feel more tired or develop gi discomfort. blood nad+ changes are not a reliable feel gauge. nr (nicotinamide riboside) is an oral supplement people look up for longevity. subtle daytime energy, less afternoon crash, or \u2018background resilience\u2019. longevity & cellular energy non-peptide systemic systemic oral nad+ precursor. systemic whole-body circulating", "legal_class": null }, { "id": 89, "slug": "collagen-peptides", "name": "Collagen peptides", "aliases": [ "hydrolyzed collagen", "collagen hydrolysate", "Hydrolyzed collagen", "Collagen hydrolysate", "Hydrolysed collagen", "Bioactive collagen peptides", "BCP (bioactive collagen peptides)", "Collagen peptide powder", "Type I/II/III collagen peptides", "Marine collagen peptides", "Bovine collagen peptides", "VERISOL", "FORTIGEL", "TENDOFORTE", "FORTIBONE", "BODYBALANCE" ], "type": "Peptide", "category": "Skin, hair & tissue remodeling", "goals_use_cases": [ "skin/hair", "joints & tendons", "recovery", "nails", "bone support (discussed)", "muscle recovery / body composition (discussed)", "connective-tissue training support", "longevity (lifestyle adjacent)", "performance continuity", "gut comfort (mixed / emerging talk)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "collagen-peptides", "collagen peptides", "collagenpeptides", "Hydrolyzed collagen", "Collagen hydrolysate", "Hydrolysed collagen", "skin/hair", "joints & tendons", "recovery", "nails", "bone support (discussed)", "muscle recovery / body composition (discussed)" ], "feel_search": [ "skin/hair", "joints & tendons", "recovery", "nails", "bone support (discussed)", "muscle recovery / body composition (discussed)" ], "summary": "Collagen peptides are hydrolyzed animal collagen fragments sold as food supplements for skin, joints and connective tissue.", "search_blob": "collagen peptides collagen-peptides hydrolyzed collagen collagen hydrolysate hydrolyzed collagen collagen hydrolysate hydrolysed collagen bioactive collagen peptides bcp (bioactive collagen peptides) collagen peptide powder type i/ii/iii collagen peptides marine collagen peptides bovine collagen peptides verisol fortigel tendoforte fortibone bodybalance collagen-peptides collagen peptides collagenpeptides hydrolyzed collagen collagen hydrolysate hydrolysed collagen skin/hair joints & tendons recovery nails bone support (discussed) muscle recovery / body composition (discussed) skin/hair joints & tendons recovery nails bone support (discussed) muscle recovery / body composition (discussed) connective-tissue training support longevity (lifestyle adjacent) performance continuity gut comfort (mixed / emerging talk) skin/hair joints & tendons recovery nails bone support (discussed) muscle recovery / body composition (discussed) collagen peptides are hydrolyzed animal collagen fragments sold as food supplements for skin, joints and connective tissue. reports include no skin change after a month, stronger nails in another user, and bloating in a long-term user. appearance, joint symptoms and gut tolerance are different outcomes. collagen peptides is a peptide people look up for skin. multi-week oral peptide trials often list less dryness and better hydration scores, especially in middle-aged cohorts. skin, hair & tissue remodeling peptide systemic whole-body \u2014 people treat this as circulating, not a local pin. systemic whole-body circulating", "legal_class": null }, { "id": 90, "slug": "creatine", "name": "Creatine monohydrate", "aliases": [ "creatine", "Creapure-class discussion", "CrM", "creatine monohydrate", "Creapure (branded monohydrate / quality shorthand)", "micronized creatine monohydrate", "creatine HCl / hydrochloride", "Kre-Alkalyn / buffered creatine", "creatine ethyl ester (CEE; historical form)", "creatine nitrate", "creatine magnesium chelate", "phosphocreatine (PCr; stored form in muscle)", "Cr (abbreviation in papers/forums)" ], "type": "Non-peptide", "category": "Performance staples (biohacking overlap)", "goals_use_cases": [ "muscle growth", "performance", "cognition", "muscle growth / lean mass", "strength & power", "high-intensity work capacity / repeat sprints", "performance (resistance training)", "recovery after hard sessions", "body composition (lean mass narratives)", "cognition / mental energy under stress", "sleep-deprivation / hypoxia performance talk", "vegan / low-meat dietary creatine gap", "women's health / peri-postmenopause + RT", "older adults / sarcopenia-adjacent training support", "bone-geometry / bone-health interest (with lifting)", "longevity / healthy-aging staple talk", "depression / brain-bioenergetics research interest" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "creatine", "Creatine monohydrate", "creatine-monohydrate", "CrM", "Creapure (branded monohydrate / quality shorthand)", "micronized creatine monohydrate", "muscle growth / lean mass", "strength & power", "high-intensity work capacity / repeat sprints", "performance (resistance training)", "recovery after hard sessions", "body composition (lean mass narratives)" ], "feel_search": [ "muscle growth / lean mass", "strength & power", "high-intensity work capacity / repeat sprints", "performance (resistance training)", "recovery after hard sessions", "body composition (lean mass narratives)" ], "summary": "Creatine monohydrate is a well-studied oral supplement that increases muscle creatine stores used in rapid energy supply.", "search_blob": "creatine monohydrate creatine creatine creapure-class discussion crm creatine monohydrate creapure (branded monohydrate / quality shorthand) micronized creatine monohydrate creatine hcl / hydrochloride kre-alkalyn / buffered creatine creatine ethyl ester (cee; historical form) creatine nitrate creatine magnesium chelate phosphocreatine (pcr; stored form in muscle) cr (abbreviation in papers/forums) creatine creatine monohydrate creatine-monohydrate crm creapure (branded monohydrate / quality shorthand) micronized creatine monohydrate muscle growth / lean mass strength & power high-intensity work capacity / repeat sprints performance (resistance training) recovery after hard sessions body composition (lean mass narratives) muscle growth performance cognition muscle growth / lean mass strength & power high-intensity work capacity / repeat sprints performance (resistance training) recovery after hard sessions body composition (lean mass narratives) cognition / mental energy under stress sleep-deprivation / hypoxia performance talk vegan / low-meat dietary creatine gap women's health / peri-postmenopause + rt older adults / sarcopenia-adjacent training support bone-geometry / bone-health interest (with lifting) longevity / healthy-aging staple talk depression / brain-bioenergetics research interest muscle growth / lean mass strength & power high-intensity work capacity / repeat sprints performance (resistance training) recovery after hard sessions body composition (lean mass narratives) creatine monohydrate is a well-studied oral supplement that increases muscle creatine stores used in rapid energy supply. a five-week user reports better training and recovery alongside bloating and weight fluctuations. separate users notice little when stopping, or mainly a scale-weight change. creatine monohydrate is an oral compound people look up for muscle. better repeat-sprint ability, denser sets, and short-rest volume once muscle stores are full. performance staples (biohacking overlap) non-peptide systemic whole-body \u2014 you eat it, it loads muscle everywhere. not a local inject. systemic whole-body circulating", "legal_class": null }, { "id": 91, "slug": "pe-22-28", "name": "PE-22-28", "aliases": [ "Spadin-related peptide discussion", "PE2228", "Mini-Spadin", "PE 22-28", "PE-2228", "PE22-28", "Spadin-related peptide (residues 22\u201328)", "Spadin analog PE 22-28", "GVSWGLR peptide", "Gly-Val-Ser-Trp-Gly-Leu-Arg", "Sortilin propeptide fragment PE 22-28", "NTSR3/Sortilin-related TREK-1 ligand (spadin-lineage)" ], "type": "Peptide", "category": "Cognitive / nootropic peptides", "goals_use_cases": [ "mood", "cognition", "depression research discussion", "mood / emotional baseline", "depression research discussion (not an approved antidepressant)", "situational / grief-type mood support discussion (clinic lore)", "anxiety-adjacent stress resilience (discussed)", "cognition secondary to mood (brain fog / clarity)", "focus / mental clarity (anecdotal nootropic framing)", "neurogenesis / synaptogenesis interest (preclinical)", "post-stroke depression models (preclinical)", "stroke recovery / motor-cognitive endpoints (preclinical)", "TREK-1 (KCNK2) mechanism curiosity", "fast-onset alternative narrative vs multi-week SSRIs (community marketing)", "stack component with Selank / Semax / DSIP / Dihexa" ], "delivery_methods": [ "nasal" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "pe-22-28", "pe 22 28", "pe2228", "Mini-Spadin", "PE 22-28", "PE-2228", "mood / emotional baseline", "depression research discussion (not an approved antidepressant)", "situational / grief-type mood support discussion (clinic lore)", "anxiety-adjacent stress resilience (discussed)", "cognition secondary to mood (brain fog / clarity)", "focus / mental clarity (anecdotal nootropic framing)" ], "feel_search": [ "mood / emotional baseline", "depression research discussion (not an approved antidepressant)", "situational / grief-type mood support discussion (clinic lore)", "anxiety-adjacent stress resilience (discussed)", "cognition secondary to mood (brain fog / clarity)", "focus / mental clarity (anecdotal nootropic framing)" ], "summary": "PE-22-28, also called Mini-Spadin, is a synthetic seven-amino-acid research peptide discussed for mood.", "search_blob": "pe-22-28 pe-22-28 spadin-related peptide discussion pe2228 mini-spadin pe 22-28 pe-2228 pe22-28 spadin-related peptide (residues 22\u201328) spadin analog pe 22-28 gvswglr peptide gly-val-ser-trp-gly-leu-arg sortilin propeptide fragment pe 22-28 ntsr3/sortilin-related trek-1 ligand (spadin-lineage) pe-22-28 pe 22 28 pe2228 mini-spadin pe 22-28 pe-2228 mood / emotional baseline depression research discussion (not an approved antidepressant) situational / grief-type mood support discussion (clinic lore) anxiety-adjacent stress resilience (discussed) cognition secondary to mood (brain fog / clarity) focus / mental clarity (anecdotal nootropic framing) mood cognition depression research discussion mood / emotional baseline depression research discussion (not an approved antidepressant) situational / grief-type mood support discussion (clinic lore) anxiety-adjacent stress resilience (discussed) cognition secondary to mood (brain fog / clarity) focus / mental clarity (anecdotal nootropic framing) neurogenesis / synaptogenesis interest (preclinical) post-stroke depression models (preclinical) stroke recovery / motor-cognitive endpoints (preclinical) trek-1 (kcnk2) mechanism curiosity fast-onset alternative narrative vs multi-week ssris (community marketing) stack component with selank / semax / dsip / dihexa mood / emotional baseline depression research discussion (not an approved antidepressant) situational / grief-type mood support discussion (clinic lore) anxiety-adjacent stress resilience (discussed) cognition secondary to mood (brain fog / clarity) focus / mental clarity (anecdotal nootropic framing) pe-22-28, also called mini-spadin, is a synthetic seven-amino-acid research peptide discussed for mood. one user described easier task-starting and clearer thinking over days to weeks; another felt worse after almost three weeks. pe-22-28 is a peptide people look up for mood. lighter affect, less emotional flatness/anhedonia, \u201ceasier to get through the day,\u201d. pe-22-28 \u2260 spadin \u2260 full sortilin propeptide; mini-spadin is a brand/nickname, not a separate molecule. gray-market labels may underdose or mis-id. cognitive / nootropic peptides peptide systemic systemic cns focus \u2014 trek-1 potassium-channel block and mood/serotonergic excitability, not a local tissue-repair peptide. systemic whole-body circulating", "legal_class": null }, { "id": 92, "slug": "adipotide", "name": "Adipotide", "aliases": [ "FTPP", "proapoptotic peptide discussion", "Fat-Targeted Proapoptotic Peptide", "FTTP (common misspelling of FTPP)", "Prohibitin-TP01", "Prohibitin-targeting peptide 1", "TP01", "CKGGRAKDC-GG-D(KLAKLAK)2", "Arrowhead Adipotide / Ablaris adipotide (historical development)" ], "type": "Peptide", "category": "Metabolic / fat-loss peptides", "goals_use_cases": [ "fat loss", "fat loss / white adipose reduction (research framing)", "body composition / visceral + subcutaneous fat volume (primate imaging)", "obesity research models", "insulin resistance / metabolic marker research (animal)", "vascular-targeted adipose ablation concept", "prostate-cancer Phase 1 MTD context (historical, terminated)", "comparison talk vs GLP-1s, AOD-9604, Frag 176-191" ], "delivery_methods": [ "research injection discussion" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "adipotide", "FTPP", "Fat-Targeted Proapoptotic Peptide", "FTTP (common misspelling of FTPP)", "Prohibitin-TP01", "Prohibitin-targeting peptide 1", "fat loss / white adipose reduction (research framing)", "body composition / visceral + subcutaneous fat volume (primate imaging)", "obesity research models", "insulin resistance / metabolic marker research (animal)", "vascular-targeted adipose ablation concept", "prostate-cancer phase 1 mtd context (historical, terminated)" ], "feel_search": [ "fat loss / white adipose reduction (research framing)", "body composition / visceral + subcutaneous fat volume (primate imaging)", "obesity research models", "insulin resistance / metabolic marker research (animal)", "vascular-targeted adipose ablation concept", "prostate-cancer phase 1 mtd context (historical, terminated)" ], "summary": "Adipotide is an experimental peptide-based compound designed to target blood vessels feeding fat tissue.", "search_blob": "adipotide adipotide ftpp proapoptotic peptide discussion fat-targeted proapoptotic peptide fttp (common misspelling of ftpp) prohibitin-tp01 prohibitin-targeting peptide 1 tp01 ckggrakdc-gg-d(klaklak)2 arrowhead adipotide / ablaris adipotide (historical development) adipotide ftpp fat-targeted proapoptotic peptide fttp (common misspelling of ftpp) prohibitin-tp01 prohibitin-targeting peptide 1 fat loss / white adipose reduction (research framing) body composition / visceral + subcutaneous fat volume (primate imaging) obesity research models insulin resistance / metabolic marker research (animal) vascular-targeted adipose ablation concept prostate-cancer phase 1 mtd context (historical, terminated) fat loss fat loss / white adipose reduction (research framing) body composition / visceral + subcutaneous fat volume (primate imaging) obesity research models insulin resistance / metabolic marker research (animal) vascular-targeted adipose ablation concept prostate-cancer phase 1 mtd context (historical, terminated) comparison talk vs glp-1s, aod-9604, frag 176-191 fat loss / white adipose reduction (research framing) body composition / visceral + subcutaneous fat volume (primate imaging) obesity research models insulin resistance / metabolic marker research (animal) vascular-targeted adipose ablation concept prostate-cancer phase 1 mtd context (historical, terminated) adipotide is an experimental peptide-based compound designed to target blood vessels feeding fat tissue. the inspected log describes brief injection burning and persistent itching. early scale losses reversed with rehydration, while the author also took tirzepatide. adipotide is a peptide people look up for fat loss. imaging write-ups describe both visceral and subcutaneous abdominal white fat falling \u2014 not only scale weight. metabolic / fat-loss peptides peptide systemic whole-body \u2014 people treat this as circulating, not a local pin. systemic whole-body circulating", "legal_class": null }, { "id": 93, "slug": "insulin", "name": "Insulin", "aliases": [ "humalog-class discussion", "slin (slang)", "Insulin (research/bodybuilding discourse)", "exogenous insulin", "Humalog / insulin lispro (rapid analog discussions)", "Novolog / NovoRapid / insulin aspart (rapid analog discussions)", "Apidra / insulin glulisine (rapid analog discussions)", "Humulin R / Novolin R / regular insulin (short-acting)", "Lantus / insulin glargine (basal long-acting talk)", "Levemir / insulin detemir (basal talk)", "Tresiba / insulin degludec (ultra-long basal contrast)", "Humulin N / NPH (intermediate; less common in pulse \u201cslin\u201d charts)" ], "type": "Peptide", "category": "Metabolic hormones", "goals_use_cases": [ "muscle", "muscle growth", "nutrient partitioning discussion", "muscle growth / hypertrophy discourse (anti-catabolic + nutrient uptake framing)", "post-workout recovery and glycogen replenishment (discussed)", "training-day fullness / pumps (discussed)", "glycogen supercompensation lore around hard sessions", "anti-catabolic / reduced proteolysis talk in the fed post-shot window", "performance enhancement / IPED polypharmacy stacks", "body recomposition and high-carb bulk support (community)", "GH-induced glucose-intolerance \u201cmanagement\u201d lore (advanced stacks)", "clinical diabetes glucose control (approved medical context \u2014 not a physique template)" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "insulin", "Insulin (research/bodybuilding discourse)", "slin (slang)", "exogenous insulin", "Humalog / insulin lispro (rapid analog discussions)", "Novolog / NovoRapid / insulin aspart (rapid analog discussions)", "muscle growth / hypertrophy discourse (anti-catabolic + nutrient uptake framing)", "nutrient partitioning discussion", "post-workout recovery and glycogen replenishment (discussed)", "training-day fullness / pumps (discussed)", "glycogen supercompensation lore around hard sessions", "anti-catabolic / reduced proteolysis talk in the fed post-shot window" ], "feel_search": [ "muscle growth / hypertrophy discourse (anti-catabolic + nutrient uptake framing)", "nutrient partitioning discussion", "post-workout recovery and glycogen replenishment (discussed)", "training-day fullness / pumps (discussed)", "glycogen supercompensation lore around hard sessions", "anti-catabolic / reduced proteolysis talk in the fed post-shot window" ], "summary": "Insulin is a blood-glucose-regulating hormone; rapid and long-acting medicines differ, and bodybuilding use carries serious hypoglycemia risk.", "search_blob": "insulin insulin humalog-class discussion slin (slang) insulin (research/bodybuilding discourse) exogenous insulin humalog / insulin lispro (rapid analog discussions) novolog / novorapid / insulin aspart (rapid analog discussions) apidra / insulin glulisine (rapid analog discussions) humulin r / novolin r / regular insulin (short-acting) lantus / insulin glargine (basal long-acting talk) levemir / insulin detemir (basal talk) tresiba / insulin degludec (ultra-long basal contrast) humulin n / nph (intermediate; less common in pulse \u201cslin\u201d charts) insulin insulin (research/bodybuilding discourse) slin (slang) exogenous insulin humalog / insulin lispro (rapid analog discussions) novolog / novorapid / insulin aspart (rapid analog discussions) muscle growth / hypertrophy discourse (anti-catabolic + nutrient uptake framing) nutrient partitioning discussion post-workout recovery and glycogen replenishment (discussed) training-day fullness / pumps (discussed) glycogen supercompensation lore around hard sessions anti-catabolic / reduced proteolysis talk in the fed post-shot window muscle muscle growth nutrient partitioning discussion muscle growth / hypertrophy discourse (anti-catabolic + nutrient uptake framing) post-workout recovery and glycogen replenishment (discussed) training-day fullness / pumps (discussed) glycogen supercompensation lore around hard sessions anti-catabolic / reduced proteolysis talk in the fed post-shot window performance enhancement / iped polypharmacy stacks body recomposition and high-carb bulk support (community) gh-induced glucose-intolerance \u201cmanagement\u201d lore (advanced stacks) clinical diabetes glucose control (approved medical context \u2014 not a physique template) muscle growth / hypertrophy discourse (anti-catabolic + nutrient uptake framing) nutrient partitioning discussion post-workout recovery and glycogen replenishment (discussed) training-day fullness / pumps (discussed) glycogen supercompensation lore around hard sessions anti-catabolic / reduced proteolysis talk in the fed post-shot window insulin is a blood-glucose-regulating hormone; rapid and long-acting medicines differ, and bodybuilding use carries serious hypoglycemia risk. gym users describe strong pumps and fullness, but the reviewed account also reported weakness and shaking despite an unchanged meal routine. effects and timing depend on the insulin formulation. insulin is a blood-glucose-regulating peptide hormone used medically for diabetes. short-term \u201cfull and hard\u201d training-day aesthetics on bulk food \u2014 water/glycogen confound large. metabolic hormones peptide systemic systemic \u2014 whole-body glucose disposal, amino-acid handling, and anti-lipolytic storage physiology. systemic whole-body circulating", "legal_class": null }, { "id": 94, "slug": "tb-4-fragments-other", "name": "TB-4 Fragment variants (non-TB-500 marketing)", "aliases": [ "TB4 frag", "thymosin fragments", "TB-4 Frag", "TB4-FRAG", "TB-4 FRAG", "Ac-SDKP", "N-acetyl-Ser-Asp-Lys-Pro", "N-acetyl-seryl-aspartyl-lysyl-proline", "TB4 Frag 1-4", "Thymosin Beta-4 Fragment (1-4)", "T\u03b24 N-terminal fragment", "Goralatide", "thymosin beta-4 fragments (non-TB-500)", "AcSDKP" ], "type": "Peptide", "category": "Healing & repair", "goals_use_cases": [ "recovery", "injury repair", "anti-fibrotic interest (discussed)", "inflammation (discussed)", "cardiac/organ repair narratives", "soft-tissue healing", "scar/fibrosis talk", "renal fibrosis research interest", "pulmonary fibrosis research interest", "hematopoietic / marrow-protection lore (goralatide history)", "performance continuity", "angiogenesis support narratives", "label/identity troubleshooting (TB4 vs TB-500 vs Ac-SDKP)" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Medium", "reach": "Mixed", "misspellings_search_terms": [ "tb-4-fragments-other", "tb 4 fragments other", "tb4fragmentsother", "TB-4 Fragment variants (non-TB-500 marketing)", "tb-4-fragment-variants-(non-tb-500-marketing)", "TB4 frag", "recovery", "injury repair", "anti-fibrotic interest (discussed)", "inflammation (discussed)", "cardiac/organ repair narratives", "soft-tissue healing" ], "feel_search": [ "recovery", "injury repair", "anti-fibrotic interest (discussed)", "inflammation (discussed)", "cardiac/organ repair narratives", "soft-tissue healing" ], "summary": "TB4 fragments are short pieces of thymosin beta-4; Ac-SDKP, TB-500 and full-length T\u03b24 are distinct identities despite overlapping labels.", "search_blob": "tb-4 fragment variants (non-tb-500 marketing) tb-4-fragments-other tb4 frag thymosin fragments tb-4 frag tb4-frag tb-4 frag ac-sdkp n-acetyl-ser-asp-lys-pro n-acetyl-seryl-aspartyl-lysyl-proline tb4 frag 1-4 thymosin beta-4 fragment (1-4) t\u03b24 n-terminal fragment goralatide thymosin beta-4 fragments (non-tb-500) acsdkp tb-4-fragments-other tb 4 fragments other tb4fragmentsother tb-4 fragment variants (non-tb-500 marketing) tb-4-fragment-variants-(non-tb-500-marketing) tb4 frag recovery injury repair anti-fibrotic interest (discussed) inflammation (discussed) cardiac/organ repair narratives soft-tissue healing recovery injury repair anti-fibrotic interest (discussed) inflammation (discussed) cardiac/organ repair narratives soft-tissue healing scar/fibrosis talk renal fibrosis research interest pulmonary fibrosis research interest hematopoietic / marrow-protection lore (goralatide history) performance continuity angiogenesis support narratives label/identity troubleshooting (tb4 vs tb-500 vs ac-sdkp) recovery injury repair anti-fibrotic interest (discussed) inflammation (discussed) cardiac/organ repair narratives soft-tissue healing tb4 fragments are short pieces of thymosin beta-4; ac-sdkp, tb-500 and full-length t\u03b24 are distinct identities despite overlapping labels. an oral tb4-frag/bpc-157 user reported no change after two weeks; responses to the combination cannot identify a fragment's effect. tb-4 fragment variants (non-tb-500 marketing) is a peptide for recovery. residual comfort or fade with load return \u2014 classic confounded recovery pattern, not pure pk residual. not a steroid, not a gh secretagogue, not interchangeable with tb-500 mg charts, not an fda-approved injury drug, not proven continuous lifelong therapy. healing & repair peptide mixed systemic ac-sdkp/tb4-fragment discussion spans anti-fibrotic research and unverified oral/subq recovery products; product identity is often unclear. mixed local systemic", "legal_class": null }, { "id": 95, "slug": "cjc-1295-dac", "name": "CJC-1295 with DAC", "aliases": [ "CJC DAC", "Drug Affinity Complex CJC", "CJC-1295 DAC", "DAC:GRF", "DAC-GRF", "CJC-1295 (with DAC)", "long-acting CJC-1295", "CJC1295 DAC", "CJC-1295", "albumin-binding CJC-1295", "ConjuChem DAC:GRF" ], "type": "Peptide", "category": "Growth hormone axis", "goals_use_cases": [ "muscle growth", "fat loss", "recovery", "body recomposition", "sleep", "performance", "anti-aging (discussed)", "IGF-1 support (discussed)", "lean mass preservation", "convenience / fewer injections", "sustained GH/IGF-1 elevation research" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "cjc-1295-dac", "cjc 1295 dac", "cjc1295dac", "CJC-1295 with DAC", "cjc-1295-with-dac", "CJC-1295 DAC", "muscle growth", "fat loss", "recovery", "body recomposition", "sleep", "performance" ], "feel_search": [ "muscle growth", "fat loss", "recovery", "body recomposition", "sleep", "performance" ], "summary": "CJC-1295 with DAC is a long-acting growth-hormone-releasing-hormone analogue designed to bind albumin and prolong exposure.", "search_blob": "cjc-1295 with dac cjc-1295-dac cjc dac drug affinity complex cjc cjc-1295 dac dac:grf dac-grf cjc-1295 (with dac) long-acting cjc-1295 cjc1295 dac cjc-1295 albumin-binding cjc-1295 conjuchem dac:grf cjc-1295-dac cjc 1295 dac cjc1295dac cjc-1295 with dac cjc-1295-with-dac cjc-1295 dac muscle growth fat loss recovery body recomposition sleep performance muscle growth fat loss recovery body recomposition sleep performance anti-aging (discussed) igf-1 support (discussed) lean mass preservation convenience / fewer injections sustained gh/igf-1 elevation research muscle growth fat loss recovery body recomposition sleep performance cjc-1295 with dac is a long-acting growth-hormone-releasing-hormone analogue designed to bind albumin and prolong exposure. one user reports water retention and stiff hands after a few weeks, then asks about persistence after stopping. the post does not establish when symptoms resolved. cjc-1295 with dac is a peptide people look up for muscle. some report deeper sleep while igf-1 is elevated; many feel little daytime difference after the first flush window. growth hormone axis peptide systemic systemic \u2014 long-acting ghrh analog with a dac that binds albumin; multi-day gh stimulation and downstream igf-1 elevation, not local tissue repair. systemic whole-body circulating", "legal_class": null }, { "id": 96, "slug": "igf-1-des", "name": "IGF-1 DES", "aliases": [ "Des(1-3)IGF-1", "IGF1 DES", "DES(1-3) IGF-1", "des(1-3)IGF-I", "IGF-DES", "IGF DES 1,3", "IGF-1 DES 1-3", "des-IGF-1", "Des-IGF-1", "truncated IGF-1", "rHuDES(1-3)IGF-1" ], "type": "Peptide", "category": "Growth factors", "goals_use_cases": [ "muscle", "muscle growth", "localized growth discussion", "localized / site-specific muscle growth (primary discussion use)", "hypertrophy of lagging body parts (calves, arms, delts, chest talk)", "satellite-cell / hyperplasia lore (community + preclinical framing)", "post-workout anabolic signaling (discussed)", "recovery / training continuity in target muscle (discussed)", "soft-tissue / tendon-ligament repair discussion (often stacked)", "performance / bodybuilding specialization blocks", "body recomposition (discussed; confounded by stacks)", "contrast tool vs systemic IGF-1 LR3" ], "delivery_methods": [ "intramuscular" ], "discussion_popularity": "Medium", "reach": "Mixed", "misspellings_search_terms": [ "igf-1-des", "igf 1 des", "igf1des", "IGF-1 DES", "Des(1-3)IGF-1", "DES(1-3) IGF-1", "localized / site-specific muscle growth (primary discussion use)", "hypertrophy of lagging body parts (calves, arms, delts, chest talk)", "satellite-cell / hyperplasia lore (community + preclinical framing)", "post-workout anabolic signaling (discussed)", "recovery / training continuity in target muscle (discussed)", "soft-tissue / tendon-ligament repair discussion (often stacked)" ], "feel_search": [ "localized / site-specific muscle growth (primary discussion use)", "hypertrophy of lagging body parts (calves, arms, delts, chest talk)", "satellite-cell / hyperplasia lore (community + preclinical framing)", "post-workout anabolic signaling (discussed)", "recovery / training continuity in target muscle (discussed)", "soft-tissue / tendon-ligament repair discussion (often stacked)" ], "summary": "IGF-1 DES is a shortened IGF-1 research analog, discussed for muscle fullness and localized growth; the site-specific growth claim is not established in humans.", "search_blob": "igf-1 des igf-1-des des(1-3)igf-1 igf1 des des(1-3) igf-1 des(1-3)igf-i igf-des igf des 1,3 igf-1 des 1-3 des-igf-1 des-igf-1 truncated igf-1 rhudes(1-3)igf-1 igf-1-des igf 1 des igf1des igf-1 des des(1-3)igf-1 des(1-3) igf-1 localized / site-specific muscle growth (primary discussion use) hypertrophy of lagging body parts (calves, arms, delts, chest talk) satellite-cell / hyperplasia lore (community + preclinical framing) post-workout anabolic signaling (discussed) recovery / training continuity in target muscle (discussed) soft-tissue / tendon-ligament repair discussion (often stacked) muscle muscle growth localized growth discussion localized / site-specific muscle growth (primary discussion use) hypertrophy of lagging body parts (calves, arms, delts, chest talk) satellite-cell / hyperplasia lore (community + preclinical framing) post-workout anabolic signaling (discussed) recovery / training continuity in target muscle (discussed) soft-tissue / tendon-ligament repair discussion (often stacked) performance / bodybuilding specialization blocks body recomposition (discussed; confounded by stacks) contrast tool vs systemic igf-1 lr3 localized / site-specific muscle growth (primary discussion use) hypertrophy of lagging body parts (calves, arms, delts, chest talk) satellite-cell / hyperplasia lore (community + preclinical framing) post-workout anabolic signaling (discussed) recovery / training continuity in target muscle (discussed) soft-tissue / tendon-ligament repair discussion (often stacked) igf-1 des is a shortened igf-1 research analog, discussed for muscle fullness and localized growth; the site-specific growth claim is not established in humans. igf-1 des is a peptide people look up for muscle. some report easier next-session readiness or less localized doms in the target site. growth factors peptide mixed mixed \u2014 usually discussed as a muscle-site injection, but systemic spillover and human des pharmacokinetics remain unresolved. mixed local systemic", "legal_class": null }, { "id": 97, "slug": "peg-igf-1", "name": "PEG-IGF-1", "aliases": [ "Pegylated IGF-1", "PEG-IGF-I", "PEGylated IGF-I", "PEG IGF-1", "PEG-IGF1", "Pegylated recombinant human IGF-1", "PEGylated recombinant human insulin-like growth factor-I", "RO5046013 (Roche clinical-research designation)", "PEG-rhIGF-I", "Long-acting IGF-1 (loose forum shorthand \u2014 not LR3)" ], "type": "Peptide", "category": "Growth factors", "goals_use_cases": [ "muscle growth", "recovery", "muscle growth / hypertrophy (discussed; sparse true-product logs)", "recovery / training continuity (discussed)", "performance", "anti-catabolism (discussed)", "soft-tissue / muscle repair talk (preclinical IM hook)", "longer-acting systemic IGF-1 exposure vs free rhIGF-1 or daily LR3", "longevity-adjacent IGF-pathway interest", "body recomposition (discussed; heavily confounded)", "dystrophy / muscle-pathology research backdrop (animal/clinical R&D, not physique approval)" ], "delivery_methods": [ "subcutaneous", "intramuscular" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "peg-igf-1", "peg igf 1", "pegigf1", "Pegylated IGF-1", "PEG-IGF-I", "PEGylated IGF-I", "muscle growth / hypertrophy (discussed; sparse true-product logs)", "recovery / training continuity (discussed)", "performance", "anti-catabolism (discussed)", "soft-tissue / muscle repair talk (preclinical im hook)", "longer-acting systemic igf-1 exposure vs free rhigf-1 or daily lr3" ], "feel_search": [ "muscle growth / hypertrophy (discussed; sparse true-product logs)", "recovery / training continuity (discussed)", "performance", "anti-catabolism (discussed)", "soft-tissue / muscle repair talk (preclinical im hook)", "longer-acting systemic igf-1 exposure vs free rhigf-1 or daily lr3" ], "summary": "PEG-IGF-1 is insulin-like growth factor 1 modified with polyethylene glycol to extend exposure; research-vial labels may not match studied material.", "search_blob": "peg-igf-1 peg-igf-1 pegylated igf-1 peg-igf-i pegylated igf-i peg igf-1 peg-igf1 pegylated recombinant human igf-1 pegylated recombinant human insulin-like growth factor-i ro5046013 (roche clinical-research designation) peg-rhigf-i long-acting igf-1 (loose forum shorthand \u2014 not lr3) peg-igf-1 peg igf 1 pegigf1 pegylated igf-1 peg-igf-i pegylated igf-i muscle growth / hypertrophy (discussed; sparse true-product logs) recovery / training continuity (discussed) performance anti-catabolism (discussed) soft-tissue / muscle repair talk (preclinical im hook) longer-acting systemic igf-1 exposure vs free rhigf-1 or daily lr3 muscle growth recovery muscle growth / hypertrophy (discussed; sparse true-product logs) recovery / training continuity (discussed) performance anti-catabolism (discussed) soft-tissue / muscle repair talk (preclinical im hook) longer-acting systemic igf-1 exposure vs free rhigf-1 or daily lr3 longevity-adjacent igf-pathway interest body recomposition (discussed; heavily confounded) dystrophy / muscle-pathology research backdrop (animal/clinical r&d, not physique approval) muscle growth / hypertrophy (discussed; sparse true-product logs) recovery / training continuity (discussed) performance anti-catabolism (discussed) soft-tissue / muscle repair talk (preclinical im hook) longer-acting systemic igf-1 exposure vs free rhigf-1 or daily lr3 peg-igf-1 is insulin-like growth factor 1 modified with polyethylene glycol to extend exposure; research-vial labels may not match studied material. the located peg-igf account combines it with peg-mgf; separate lr3 pump and appetite reports do not isolate peg-igf. peg-igf-1 is a peptide people look up for muscle. soft recovery and \u201cbounce-back\u201d claims appear, but true peg-igf-1 solo logs are thinner than lr3 or peg-mgf threads. growth factors peptide systemic whole-body \u2014 people treat this as circulating, not a local pin. systemic whole-body circulating", "legal_class": null }, { "id": 98, "slug": "thymalin", "name": "Thymalin", "aliases": [ "thymic bioregulator", "KEW peptide complex discussion", "Thymic bioregulator", "Thymus polypeptide complex", "Thymalinum", "Thymalin (calf thymus extract)", "Thymus polypeptide fraction", "KEW peptide complex (discussion)", "Khavinson thymic complex", "CAS 79621-14-0 (complex preparation, discussion)" ], "type": "Peptide", "category": "Longevity & bioregulators", "goals_use_cases": [ "immune", "longevity", "immune aging / immunosenescence (discussed)", "infection recovery support (discussed)", "T-cell balance (discussed)", "hematopoiesis support (discussed)", "geroprotection (research framing)", "post-illness convalescence (discussed)", "COVID-era adjunct discussion (Russian reports)", "annual immune tune-up (longevity stacks)", "lymphopenia / lymphocyte recovery narratives", "vs Thymosin Alpha-1 comparison shopping" ], "delivery_methods": [ "injection", "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "thymalin", "Thymic bioregulator", "Thymus polypeptide complex", "Thymalinum", "Thymalin (calf thymus extract)", "Thymus polypeptide fraction", "immune", "longevity", "immune aging / immunosenescence (discussed)", "infection recovery support (discussed)", "t-cell balance (discussed)", "hematopoiesis support (discussed)" ], "feel_search": [ "immune", "longevity", "immune aging / immunosenescence (discussed)", "infection recovery support (discussed)", "t-cell balance (discussed)", "hematopoiesis support (discussed)" ], "summary": "Thymalin is a calf-thymus peptide extract containing multiple fractions, used in the Russian immune-bioregulator tradition.", "search_blob": "thymalin thymalin thymic bioregulator kew peptide complex discussion thymic bioregulator thymus polypeptide complex thymalinum thymalin (calf thymus extract) thymus polypeptide fraction kew peptide complex (discussion) khavinson thymic complex cas 79621-14-0 (complex preparation, discussion) thymalin thymic bioregulator thymus polypeptide complex thymalinum thymalin (calf thymus extract) thymus polypeptide fraction immune longevity immune aging / immunosenescence (discussed) infection recovery support (discussed) t-cell balance (discussed) hematopoiesis support (discussed) immune longevity immune aging / immunosenescence (discussed) infection recovery support (discussed) t-cell balance (discussed) hematopoiesis support (discussed) geroprotection (research framing) post-illness convalescence (discussed) covid-era adjunct discussion (russian reports) annual immune tune-up (longevity stacks) lymphopenia / lymphocyte recovery narratives vs thymosin alpha-1 comparison shopping immune longevity immune aging / immunosenescence (discussed) infection recovery support (discussed) t-cell balance (discussed) hematopoiesis support (discussed) thymalin is a calf-thymus peptide extract containing multiple fractions, used in the russian immune-bioregulator tradition. one user reported staying active with a shorter-feeling chest cold, while a separate commenter reported a migraine-like headache. thymalin is a peptide people look up for immune support. fewer colds or shorter uris claimed after seasonal courses; expect high lifestyle confounding. longevity & bioregulators peptide systemic systemic \u2014 multi-peptide thymic bioregulator framed for immune, blood-cell, and age-related immune regulation, not a local soft-tissue injury agent. systemic whole-body circulating", "legal_class": null }, { "id": 99, "slug": "vilon", "name": "Vilon", "aliases": [ "KE peptide", "thymus bioregulator Vilon", "Lys-Glu", "L-Lys-L-Glu", "lysylglutamic acid", "lysyl glutamate", "Vilon\u00ae (research / originator trade discussion)", "cytogen KE", "synthetic thymic dipeptide Lys-Glu" ], "type": "Peptide", "category": "Longevity & bioregulators", "goals_use_cases": [ "immune", "longevity", "immune modulation / immunosenescence (discussed)", "thymus / T-cell differentiation support (preclinical framing)", "longevity / geroprotection (rodent lineage)", "cellular aging and chromatin / gene-expression research", "anti-inflammaging narratives", "recovery continuity and infection-season resilience (community)", "coagulation / hemostasis marker research (small human cohort)", "multi-bioregulator longevity stacks (not solo hero compound)" ], "delivery_methods": [ "oral", "injection discussion" ], "discussion_popularity": "Medium", "reach": "Mixed", "misspellings_search_terms": [ "vilon", "KE peptide", "Lys-Glu", "L-Lys-L-Glu", "lysylglutamic acid", "lysyl glutamate", "immune modulation / immunosenescence (discussed)", "thymus / t-cell differentiation support (preclinical framing)", "longevity / geroprotection (rodent lineage)", "cellular aging and chromatin / gene-expression research", "anti-inflammaging narratives", "recovery continuity and infection-season resilience (community)" ], "feel_search": [ "immune modulation / immunosenescence (discussed)", "thymus / t-cell differentiation support (preclinical framing)", "longevity / geroprotection (rodent lineage)", "cellular aging and chromatin / gene-expression research", "anti-inflammaging narratives", "recovery continuity and infection-season resilience (community)" ], "summary": "Vilon is the synthetic Lys-Glu dipeptide from thymus-bioregulator research, discussed for immune and aging-related interests.", "search_blob": "vilon vilon ke peptide thymus bioregulator vilon lys-glu l-lys-l-glu lysylglutamic acid lysyl glutamate vilon\u00ae (research / originator trade discussion) cytogen ke synthetic thymic dipeptide lys-glu vilon ke peptide lys-glu l-lys-l-glu lysylglutamic acid lysyl glutamate immune modulation / immunosenescence (discussed) thymus / t-cell differentiation support (preclinical framing) longevity / geroprotection (rodent lineage) cellular aging and chromatin / gene-expression research anti-inflammaging narratives recovery continuity and infection-season resilience (community) immune longevity immune modulation / immunosenescence (discussed) thymus / t-cell differentiation support (preclinical framing) longevity / geroprotection (rodent lineage) cellular aging and chromatin / gene-expression research anti-inflammaging narratives recovery continuity and infection-season resilience (community) coagulation / hemostasis marker research (small human cohort) multi-bioregulator longevity stacks (not solo hero compound) immune modulation / immunosenescence (discussed) thymus / t-cell differentiation support (preclinical framing) longevity / geroprotection (rodent lineage) cellular aging and chromatin / gene-expression research anti-inflammaging narratives recovery continuity and infection-season resilience (community) vilon is the synthetic lys-glu dipeptide from thymus-bioregulator research, discussed for immune and aging-related interests. one vip/vilon user initially described much more energy and clearer thinking, then later said the benefit was not durable. vilon is a peptide people look up for immune support. some users claim delayed \u201cfewer colds\u201d or steadier energy; causality is weak without illness-exposure tracking. longevity & bioregulators peptide mixed mixed-systemic \u2014 short thymus-addressed dipeptide framed for whole-body immune, chromatin, and geroprotective effects, not local soft-tissue repair. mixed local systemic", "legal_class": null }, { "id": 100, "slug": "cartalax", "name": "Cartalax", "aliases": [ "cartilage bioregulator", "AED peptide discussion", "AED peptide", "Ala-Glu-Asp", "Alanyl-glutamyl-aspartic acid", "T-31", "AC-4", "AC4", "Cartalax Cytogen", "Khavinson cartilage peptide", "cartilage and bone tissue bioregulator" ], "type": "Peptide", "category": "Longevity & bioregulators", "goals_use_cases": [ "joints & tendons", "recovery", "cartilage / connective tissue (discussed)", "osteoarthritis / wear-and-tear narratives", "longevity / musculoskeletal aging", "mobility & morning stiffness (community)", "bone\u2013cartilage axis discussion (product literature)", "inflammation moderation (discussed)", "performance continuity under joint load", "post-injury or post-fracture rehab adjunct (discussed)", "spinal osteochondrosis / degenerative spine talk (Russian product literature)" ], "delivery_methods": [ "oral", "injection discussion" ], "discussion_popularity": "Medium", "reach": "Mixed", "misspellings_search_terms": [ "cartalax", "AED peptide", "Ala-Glu-Asp", "Alanyl-glutamyl-aspartic acid", "T-31", "AC-4", "joints & tendons", "recovery", "cartilage / connective tissue (discussed)", "osteoarthritis / wear-and-tear narratives", "longevity / musculoskeletal aging", "mobility & morning stiffness (community)" ], "feel_search": [ "joints & tendons", "recovery", "cartilage / connective tissue (discussed)", "osteoarthritis / wear-and-tear narratives", "longevity / musculoskeletal aging", "mobility & morning stiffness (community)" ], "summary": "Cartalax is the synthetic tripeptide AED, marketed as a cartilage and bone bioregulator for joint-related goals.", "search_blob": "cartalax cartalax cartilage bioregulator aed peptide discussion aed peptide ala-glu-asp alanyl-glutamyl-aspartic acid t-31 ac-4 ac4 cartalax cytogen khavinson cartilage peptide cartilage and bone tissue bioregulator cartalax aed peptide ala-glu-asp alanyl-glutamyl-aspartic acid t-31 ac-4 joints & tendons recovery cartilage / connective tissue (discussed) osteoarthritis / wear-and-tear narratives longevity / musculoskeletal aging mobility & morning stiffness (community) joints & tendons recovery cartilage / connective tissue (discussed) osteoarthritis / wear-and-tear narratives longevity / musculoskeletal aging mobility & morning stiffness (community) bone\u2013cartilage axis discussion (product literature) inflammation moderation (discussed) performance continuity under joint load post-injury or post-fracture rehab adjunct (discussed) spinal osteochondrosis / degenerative spine talk (russian product literature) joints & tendons recovery cartilage / connective tissue (discussed) osteoarthritis / wear-and-tear narratives longevity / musculoskeletal aging mobility & morning stiffness (community) cartalax is the synthetic tripeptide aed, marketed as a cartilage and bone bioregulator for joint-related goals. in the same thread, one person reports marked hip-arthritis relief while another reports none after two courses. neither account proves cartilage regrowth. cartalax is a peptide people look up for joints. mild stiffness ease, easier warm-up, or still nothing \u2014 checkpoint often at course end, not day 2. longevity & bioregulators peptide mixed discussed for cartilage and connective tissue, with oral or injectable exposure rather than proven local delivery. mixed local systemic", "legal_class": null }, { "id": 101, "slug": "vesugen", "name": "Vesugen", "aliases": [ "vascular bioregulator", "KED peptide", "KED", "Lys-Glu-Asp", "Lysyl-glutamyl-aspartic acid", "H-Lys-Glu-Asp-OH", "Vezugen (Russian transliteration)", "Vesogen (common misspelling)", "T-38 (research designation)", "Khavinson vascular tripeptide", "vascular cytogen (Khavinson class)" ], "type": "Peptide", "category": "Longevity & bioregulators", "goals_use_cases": [ "blood flow", "gym pumps", "erections", "vascular discussion", "longevity", "vascular health / endothelial support (discussed)", "longevity / geroprotection narratives", "circulation / microcirculation / blood-flow talk", "cardiovascular aging interest", "atherosclerosis / arterial-insufficiency research context", "vasculogenic erectile-function discussion", "cerebral perfusion / cognitive-support stacks (secondary)", "performance continuity via vascular comfort (anecdotal)", "cytogen \u2192 cytomax vascular sequencing (with Ventfort)" ], "delivery_methods": [ "oral", "injection discussion" ], "discussion_popularity": "Emerging", "reach": "Mixed", "misspellings_search_terms": [ "vesugen", "KED peptide", "KED", "Lys-Glu-Asp", "Lysyl-glutamyl-aspartic acid", "H-Lys-Glu-Asp-OH", "russian cialis", "vesugen peptide", "vascular health / endothelial support (discussed)", "longevity / geroprotection narratives", "circulation / microcirculation / blood-flow talk", "cardiovascular aging interest", "atherosclerosis / arterial-insufficiency research context", "vasculogenic erectile-function discussion", "blood flow", "gym pumps", "veins", "cardio", "erections", "brain fog", "cialis" ], "feel_search": [ "vascular health / endothelial support (discussed)", "longevity / geroprotection narratives", "circulation / microcirculation / blood-flow talk", "cardiovascular aging interest", "atherosclerosis / arterial-insufficiency research context", "vasculogenic erectile-function discussion", "blood flow", "gym pumps", "veins", "cardio", "erections", "brain fog", "cialis" ], "summary": "Vesugen is a short Russian vessel peptide. People look it up for pumps, circulation, cardio, and erections. Reports include stronger veins, no change, and feeling weak and foggy.", "search_blob": "vesugen vesugen vascular bioregulator ked peptide ked lys-glu-asp lysyl-glutamyl-aspartic acid h-lys-glu-asp-oh vezugen (russian transliteration) vesogen (common misspelling) t-38 (research designation) khavinson vascular tripeptide vascular cytogen (khavinson class) vesugen ked peptide ked lys-glu-asp lysyl-glutamyl-aspartic acid h-lys-glu-asp-oh russian cialis vesugen peptide vascular health / endothelial support (discussed) longevity / geroprotection narratives circulation / microcirculation / blood-flow talk cardiovascular aging interest atherosclerosis / arterial-insufficiency research context vasculogenic erectile-function discussion blood flow gym pumps veins cardio erections brain fog cialis blood flow gym pumps erections vascular discussion longevity vascular health / endothelial support (discussed) longevity / geroprotection narratives circulation / microcirculation / blood-flow talk cardiovascular aging interest atherosclerosis / arterial-insufficiency research context vasculogenic erectile-function discussion cerebral perfusion / cognitive-support stacks (secondary) performance continuity via vascular comfort (anecdotal) cytogen \u2192 cytomax vascular sequencing (with ventfort) vascular health / endothelial support (discussed) longevity / geroprotection narratives circulation / microcirculation / blood-flow talk cardiovascular aging interest atherosclerosis / arterial-insufficiency research context vasculogenic erectile-function discussion blood flow gym pumps veins cardio erections brain fog cialis vesugen is a short russian vessel peptide. people look it up for pumps, circulation, cardio, and erections. reports include stronger veins, no change, and feeling weak and foggy. vesugen is a short russian vessel peptide. people look it up for pumps, circulation, cardio, and erections. reports include stronger veins, no change, and feeling weak and foggy. longevity & bioregulators peptide mixed mixed \u2014 vascular-targeted framing, but oral, sublingual and subq use is systemic rather than a local vessel treatment. mixed local systemic", "legal_class": null }, { "id": 102, "slug": "cardiogen", "name": "Cardiogen", "aliases": [ "heart bioregulator", "Ala-Glu-Asp-Arg discussion", "AEDR", "Ala-Glu-Asp-Arg", "H-Ala-Glu-Asp-Arg-OH", "AEDR tetrapeptide", "cardiac bioregulator peptide", "Cardiogen peptide", "Khavinson AEDR", "Khavinson heart tetrapeptide", "cardiac Cytogen (synthetic class talk)", "T-30 (vendor shorthand, inconsistent)", "AED (vendor shorthand \u2014 sometimes confuses sequence count)", "PubChem CID 11583989 (listed on secondary research pages)" ], "type": "Peptide", "category": "Longevity & bioregulators", "goals_use_cases": [ "cardiovascular discussion", "longevity", "cardiovascular discussion / heart-tissue bioregulator framing", "longevity / healthspan multi-organ calendars", "heart tissue repair / remodeling interest (research context)", "cardiac scar / fibroblast-modulation narratives", "endurance / circulation / oxygen-use feel (community)", "post-stress or post-PED cardio recovery (community)", "fibroblast / inflammaging / SASP research interest", "aging cardiovascular support narratives", "post-MI / ischemic recovery talk (preclinical + marketing only)", "blood-pressure comfort narratives (anecdotal, not Rx substitute)", "vs Vesugen / Chelohart / Cardiolax identity searches", "PCT-adjacent heart support talk in hard-training circles" ], "delivery_methods": [ "oral", "injection discussion" ], "discussion_popularity": "Emerging", "reach": "Mixed", "misspellings_search_terms": [ "cardiogen", "AEDR", "Ala-Glu-Asp-Arg", "H-Ala-Glu-Asp-Arg-OH", "AEDR tetrapeptide", "heart bioregulator", "cardiovascular discussion / heart-tissue bioregulator framing", "longevity / healthspan multi-organ calendars", "heart tissue repair / remodeling interest (research context)", "cardiac scar / fibroblast-modulation narratives", "endurance / circulation / oxygen-use feel (community)", "post-stress or post-ped cardio recovery (community)" ], "feel_search": [ "cardiovascular discussion / heart-tissue bioregulator framing", "longevity / healthspan multi-organ calendars", "heart tissue repair / remodeling interest (research context)", "cardiac scar / fibroblast-modulation narratives", "endurance / circulation / oxygen-use feel (community)", "post-stress or post-ped cardio recovery (community)" ], "summary": "Cardiogen is the synthetic tetrapeptide AEDR, marketed as a heart bioregulator and studied in preclinical tissue research.", "search_blob": "cardiogen cardiogen heart bioregulator ala-glu-asp-arg discussion aedr ala-glu-asp-arg h-ala-glu-asp-arg-oh aedr tetrapeptide cardiac bioregulator peptide cardiogen peptide khavinson aedr khavinson heart tetrapeptide cardiac cytogen (synthetic class talk) t-30 (vendor shorthand, inconsistent) aed (vendor shorthand \u2014 sometimes confuses sequence count) pubchem cid 11583989 (listed on secondary research pages) cardiogen aedr ala-glu-asp-arg h-ala-glu-asp-arg-oh aedr tetrapeptide heart bioregulator cardiovascular discussion / heart-tissue bioregulator framing longevity / healthspan multi-organ calendars heart tissue repair / remodeling interest (research context) cardiac scar / fibroblast-modulation narratives endurance / circulation / oxygen-use feel (community) post-stress or post-ped cardio recovery (community) cardiovascular discussion longevity cardiovascular discussion / heart-tissue bioregulator framing longevity / healthspan multi-organ calendars heart tissue repair / remodeling interest (research context) cardiac scar / fibroblast-modulation narratives endurance / circulation / oxygen-use feel (community) post-stress or post-ped cardio recovery (community) fibroblast / inflammaging / sasp research interest aging cardiovascular support narratives post-mi / ischemic recovery talk (preclinical + marketing only) blood-pressure comfort narratives (anecdotal, not rx substitute) vs vesugen / chelohart / cardiolax identity searches pct-adjacent heart support talk in hard-training circles cardiovascular discussion / heart-tissue bioregulator framing longevity / healthspan multi-organ calendars heart tissue repair / remodeling interest (research context) cardiac scar / fibroblast-modulation narratives endurance / circulation / oxygen-use feel (community) post-stress or post-ped cardio recovery (community) cardiogen is the synthetic tetrapeptide aedr, marketed as a heart bioregulator and studied in preclinical tissue research. one user reports higher nighttime resting heart rate and an improvement after changing timing; another reports lower heart rate and blood pressure. cardiogen is a peptide people look up for longevity. active window in short-course models \u2014 subtle energy, breathing-ease, training-load continuity, or still nothing. longevity & bioregulators peptide mixed cardiac-tissue research and whole-body community use; tissue selectivity does not establish targeted delivery. mixed local systemic", "legal_class": null }, { "id": 103, "slug": "livagen", "name": "Livagen", "aliases": [ "liver bioregulator", "KEDA peptide discussion", "KEDA", "KEDA peptide", "Lys-Glu-Asp-Ala", "H-Lys-Glu-Asp-Ala-OH", "H-KEDA-OH", "Livagen peptide", "Khavinson liver tetrapeptide", "SCHEMBL5967826", "lysyl-glutamyl-aspartylalanine" ], "type": "Peptide", "category": "Longevity & bioregulators", "goals_use_cases": [ "liver support discussion", "longevity", "longevity / geroprotector stacks", "hepatoprotection (preclinical / discussed)", "immune aging / lymphocyte chromatin talk", "chromatin / gene-expression narratives", "digestive enzyme aging discussion", "antioxidant / hepatic stress models", "post-alcohol or bulk \u2018liver load\u2019 recovery talk", "enkephalinase / endogenous opioid enzyme talk", "multi-organ bioregulator kits (liver slot)", "vs Ovagen / Svetinorm dual-liver framing" ], "delivery_methods": [ "oral", "injection discussion" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "livagen", "KEDA", "KEDA peptide", "Lys-Glu-Asp-Ala", "H-Lys-Glu-Asp-Ala-OH", "H-KEDA-OH", "liver support discussion", "longevity / geroprotector stacks", "hepatoprotection (preclinical / discussed)", "immune aging / lymphocyte chromatin talk", "chromatin / gene-expression narratives", "digestive enzyme aging discussion" ], "feel_search": [ "liver support discussion", "longevity / geroprotector stacks", "hepatoprotection (preclinical / discussed)", "immune aging / lymphocyte chromatin talk", "chromatin / gene-expression narratives", "digestive enzyme aging discussion" ], "summary": "Livagen is the synthetic four-amino-acid peptide KEDA, studied in preclinical liver-cell work and discussed as a liver or aging bioregulator.", "search_blob": "livagen livagen liver bioregulator keda peptide discussion keda keda peptide lys-glu-asp-ala h-lys-glu-asp-ala-oh h-keda-oh livagen peptide khavinson liver tetrapeptide schembl5967826 lysyl-glutamyl-aspartylalanine livagen keda keda peptide lys-glu-asp-ala h-lys-glu-asp-ala-oh h-keda-oh liver support discussion longevity / geroprotector stacks hepatoprotection (preclinical / discussed) immune aging / lymphocyte chromatin talk chromatin / gene-expression narratives digestive enzyme aging discussion liver support discussion longevity longevity / geroprotector stacks hepatoprotection (preclinical / discussed) immune aging / lymphocyte chromatin talk chromatin / gene-expression narratives digestive enzyme aging discussion antioxidant / hepatic stress models post-alcohol or bulk \u2018liver load\u2019 recovery talk enkephalinase / endogenous opioid enzyme talk multi-organ bioregulator kits (liver slot) vs ovagen / svetinorm dual-liver framing liver support discussion longevity / geroprotector stacks hepatoprotection (preclinical / discussed) immune aging / lymphocyte chromatin talk chromatin / gene-expression narratives digestive enzyme aging discussion livagen is the synthetic four-amino-acid peptide keda, studied in preclinical liver-cell work and discussed as a liver or aging bioregulator. reports are sparse and conflicting: claimed liver or recovery benefits are often stacked, while one user described severe anxiety and heart symptoms. a reliable typical feel is not established. livagen is a peptide people look up for longevity. mild recovery/energy, \u2018liver feel\u2019 stories, or explicit null. longevity & bioregulators peptide systemic systemic \u2014 liver-directed marketing does not establish liver-selective delivery in humans. systemic whole-body circulating", "legal_class": null }, { "id": 104, "slug": "ovagen", "name": "Ovagen", "aliases": [ "liver/GI bioregulator discussions vary by source", "Ovagen bioregulator", "Glu-Asp-Leu", "EDL tripeptide", "EDL", "glutamyl-aspartyl-leucine", "Ovagen Cytogen", "liver/GI bioregulator (Khavinson class)", "Ovagen lingual", "AC-3 complex (vendor identity debates)", "C15H25N3O8 (~375.37\u2013375.4 g/mol free EDL form)", "SCHEMBL5329396 / CHEBI:137252 / PubChem CID 444128 (EDL listings vary by source)", "CAS 9046-70-2 (listed on some research-chem pages \u2014 verify; not a universal registry truth)" ], "type": "Peptide", "category": "Longevity & bioregulators", "goals_use_cases": [ "gut health", "liver support discussion", "gut health / GI mucosa support (discussed)", "longevity / organ bioregulator calendars", "detoxification capacity narratives", "metabolic / bile / fat-meal tolerance talk", "age-related hepatic decline (discussed)", "NAFLD / fatty-liver adjunct talk", "post-alcohol or medication hepatic-stress recovery (discussed)", "bodybuilding / oral-compound post-cycle liver talk", "post-hepatitis recovery adjunct (discussed; medical care primary)", "chemo / antibiotic / toxin mucosal-protection narratives (research framing)", "gut\u2013liver axis optimization talk", "inflammatory-bowel adjunct narratives (sparse evidence; medical care primary)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "ovagen", "Ovagen bioregulator", "Glu-Asp-Leu", "EDL tripeptide", "EDL", "glutamyl-aspartyl-leucine", "gut health / gi mucosa support (discussed)", "liver support discussion", "longevity / organ bioregulator calendars", "detoxification capacity narratives", "metabolic / bile / fat-meal tolerance talk", "age-related hepatic decline (discussed)" ], "feel_search": [ "gut health / gi mucosa support (discussed)", "liver support discussion", "longevity / organ bioregulator calendars", "detoxification capacity narratives", "metabolic / bile / fat-meal tolerance talk", "age-related hepatic decline (discussed)" ], "summary": "Ovagen is a synthetic three-amino-acid peptide sold as a liver bioregulator; it is distinct from mixed liver-extract capsules.", "search_blob": "ovagen ovagen liver/gi bioregulator discussions vary by source ovagen bioregulator glu-asp-leu edl tripeptide edl glutamyl-aspartyl-leucine ovagen cytogen liver/gi bioregulator (khavinson class) ovagen lingual ac-3 complex (vendor identity debates) c15h25n3o8 (~375.37\u2013375.4 g/mol free edl form) schembl5329396 / chebi:137252 / pubchem cid 444128 (edl listings vary by source) cas 9046-70-2 (listed on some research-chem pages \u2014 verify; not a universal registry truth) ovagen ovagen bioregulator glu-asp-leu edl tripeptide edl glutamyl-aspartyl-leucine gut health / gi mucosa support (discussed) liver support discussion longevity / organ bioregulator calendars detoxification capacity narratives metabolic / bile / fat-meal tolerance talk age-related hepatic decline (discussed) gut health liver support discussion gut health / gi mucosa support (discussed) longevity / organ bioregulator calendars detoxification capacity narratives metabolic / bile / fat-meal tolerance talk age-related hepatic decline (discussed) nafld / fatty-liver adjunct talk post-alcohol or medication hepatic-stress recovery (discussed) bodybuilding / oral-compound post-cycle liver talk post-hepatitis recovery adjunct (discussed; medical care primary) chemo / antibiotic / toxin mucosal-protection narratives (research framing) gut\u2013liver axis optimization talk inflammatory-bowel adjunct narratives (sparse evidence; medical care primary) gut health / gi mucosa support (discussed) liver support discussion longevity / organ bioregulator calendars detoxification capacity narratives metabolic / bile / fat-meal tolerance talk age-related hepatic decline (discussed) ovagen is a synthetic three-amino-acid peptide sold as a liver bioregulator; it is distinct from mixed liver-extract capsules. often little is noticed beyond possible gi discomfort or injection sting. claimed liver or digestion improvements are difficult to separate from other products and changing labs. ovagen is a peptide people look up for gut. subjective easier digestion, less post-meal heaviness, less bloating after short oral cycles \u2014 highly variable; many report null. longevity & bioregulators peptide systemic systemic oral/injected exposure is discussed; liver/gi targeting is a research or marketing claim, not proven selective delivery. systemic whole-body circulating", "legal_class": null }, { "id": 105, "slug": "prostamax", "name": "Prostamax", "aliases": [ "prostate bioregulator", "KEDP peptide", "KEDP", "Lys-Glu-Asp-Pro", "Lysyl-glutamyl-aspartyl-proline", "H-Lys-Glu-Asp-Pro-OH", "Prostamax peptide", "synthetic prostate tetrapeptide", "Khavinson prostate peptide" ], "type": "Peptide", "category": "Longevity & bioregulators", "goals_use_cases": [ "men's health discussion", "prostate support narratives", "urinary comfort / nocturia interest (community)", "chronic prostatitis research context (preclinical)", "BPH-adjacent talk (community; evidence mostly extract or animal)", "longevity / chromatin-aging interest", "inflammation and tissue-repair narratives", "urologic wellness interest (community)", "libido / sexual-function halo (often stacked or extract-confounded)" ], "delivery_methods": [ "oral", "injection discussion" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "prostamax", "KEDP", "KEDP peptide", "Lys-Glu-Asp-Pro", "Lysyl-glutamyl-aspartyl-proline", "H-Lys-Glu-Asp-Pro-OH", "men's health discussion", "prostate support narratives", "urinary comfort / nocturia interest (community)", "chronic prostatitis research context (preclinical)", "bph-adjacent talk (community; evidence mostly extract or animal)", "longevity / chromatin-aging interest" ], "feel_search": [ "men's health discussion", "prostate support narratives", "urinary comfort / nocturia interest (community)", "chronic prostatitis research context (preclinical)", "bph-adjacent talk (community; evidence mostly extract or animal)", "longevity / chromatin-aging interest" ], "summary": "Prostamax is the synthetic four-amino-acid peptide KEDP, a Russian bioregulator discussed for prostate-related symptoms.", "search_blob": "prostamax prostamax prostate bioregulator kedp peptide kedp lys-glu-asp-pro lysyl-glutamyl-aspartyl-proline h-lys-glu-asp-pro-oh prostamax peptide synthetic prostate tetrapeptide khavinson prostate peptide prostamax kedp kedp peptide lys-glu-asp-pro lysyl-glutamyl-aspartyl-proline h-lys-glu-asp-pro-oh men's health discussion prostate support narratives urinary comfort / nocturia interest (community) chronic prostatitis research context (preclinical) bph-adjacent talk (community; evidence mostly extract or animal) longevity / chromatin-aging interest men's health discussion prostate support narratives urinary comfort / nocturia interest (community) chronic prostatitis research context (preclinical) bph-adjacent talk (community; evidence mostly extract or animal) longevity / chromatin-aging interest inflammation and tissue-repair narratives urologic wellness interest (community) libido / sexual-function halo (often stacked or extract-confounded) men's health discussion prostate support narratives urinary comfort / nocturia interest (community) chronic prostatitis research context (preclinical) bph-adjacent talk (community; evidence mostly extract or animal) longevity / chromatin-aging interest prostamax is the synthetic four-amino-acid peptide kedp, a russian bioregulator discussed for prostate-related symptoms. one user described a steadier urine stream and fewer nighttime trips, while also taping their mouth and drinking less overnight. prostamax is a peptide people look up for prostate. easier stream, less night waking, or milder pelvic pressure. longevity & bioregulators peptide systemic systemic use is discussed for prostate goals; synthetic kedp, animal-prostate extracts and herbal products are not interchangeable. systemic whole-body circulating", "legal_class": null }, { "id": 106, "slug": "testagen", "name": "Testagen", "aliases": [ "testicular bioregulator", "KEDG peptide", "KEDG", "Lys-Glu-Asp-Gly", "H-Lys-Glu-Asp-Gly-OH", "H-KEDG-OH", "Testagen Cytogen", "Anterior Pituitary Peptide (APP) (vendor label discussions)", "Khavinson testis tetrapeptide", "testis peptide bioregulator" ], "type": "Peptide", "category": "Longevity & bioregulators", "goals_use_cases": [ "hormone axis", "men's health discussion", "hormone axis / HPG support narratives", "age-related low-T talk (community)", "libido (discussed)", "thyroid interest (TSH / T3 / T4 talk)", "testicular / reproductive support narratives", "chronic prostatitis adjunct talk (older writeups)", "longevity / bioregulator courses", "energy & recovery (community)", "fertility-preserving alternative-to-TRT searches", "PCT / post-cycle recovery talk (minority community)", "vs Testoluten / extract sequencing" ], "delivery_methods": [ "oral", "injection discussion" ], "discussion_popularity": "Emerging", "reach": "Mixed", "misspellings_search_terms": [ "testagen", "KEDG peptide", "KEDG", "Lys-Glu-Asp-Gly", "H-Lys-Glu-Asp-Gly-OH", "H-KEDG-OH", "hormone axis / hpg support narratives", "men's health discussion", "age-related low-t talk (community)", "libido (discussed)", "thyroid interest (tsh / t3 / t4 talk)", "testicular / reproductive support narratives" ], "feel_search": [ "hormone axis / hpg support narratives", "men's health discussion", "age-related low-t talk (community)", "libido (discussed)", "thyroid interest (tsh / t3 / t4 talk)", "testicular / reproductive support narratives" ], "summary": "Testagen is the synthetic four-amino-acid peptide KEDG, discussed as a bioregulator for endocrine and testosterone-related interests.", "search_blob": "testagen testagen testicular bioregulator kedg peptide kedg lys-glu-asp-gly h-lys-glu-asp-gly-oh h-kedg-oh testagen cytogen anterior pituitary peptide (app) (vendor label discussions) khavinson testis tetrapeptide testis peptide bioregulator testagen kedg peptide kedg lys-glu-asp-gly h-lys-glu-asp-gly-oh h-kedg-oh hormone axis / hpg support narratives men's health discussion age-related low-t talk (community) libido (discussed) thyroid interest (tsh / t3 / t4 talk) testicular / reproductive support narratives hormone axis men's health discussion hormone axis / hpg support narratives age-related low-t talk (community) libido (discussed) thyroid interest (tsh / t3 / t4 talk) testicular / reproductive support narratives chronic prostatitis adjunct talk (older writeups) longevity / bioregulator courses energy & recovery (community) fertility-preserving alternative-to-trt searches pct / post-cycle recovery talk (minority community) vs testoluten / extract sequencing hormone axis / hpg support narratives men's health discussion age-related low-t talk (community) libido (discussed) thyroid interest (tsh / t3 / t4 talk) testicular / reproductive support narratives testagen is the synthetic four-amino-acid peptide kedg, discussed as a bioregulator for endocrine and testosterone-related interests. one user reported more energy, libido and gym strength while measured testosterone stayed near their previous level and several peptides were co-used. testagen is a peptide people look up for libido. multi-week course logs of better sex drive or bedroom performance; heavily confounded by sleep, fat loss, stacks, and expectancy. longevity & bioregulators peptide mixed mixed \u2014 marketed for reproductive and hormone-related bioregulator effects, with oral or injectable exposure; not a local injury-site agent. mixed local systemic", "legal_class": null }, { "id": 107, "slug": "cerluten", "name": "Cerluten", "aliases": [ "brain bioregulator", "brain peptide complex", "Cerluten\u00ae", "A-5", "Cytomax A-5", "peptide complex A-5", "CNS peptide bioregulator", "nerve cell peptides (marketing)", "Nature\u2019s Marvels CNS / Central Nervous System Bioregulator (related product line)", "Lingual Cerluten (sublingual form discussed)" ], "type": "Peptide", "category": "Longevity & bioregulators", "goals_use_cases": [ "cognition", "longevity", "cognition / memory & attention", "mental capacity maintenance in aging", "neuroprotection (discussed)", "longevity / Khavinson cytomax courses", "post-stroke residual symptoms (historical clinical add-on)", "long-term TBI / craniocerebral injury sequelae (historical clinical add-on)", "vascular encephalopathy support talk", "stress resilience / emotional stability (discussed)", "sleep quality (secondary discussion)", "headache and mental fatigue burden (subjective clinical series)", "healthy aging brain support stacks" ], "delivery_methods": [ "oral", "injection discussion" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "cerluten", "Cerluten\u00ae", "A-5", "Cytomax A-5", "peptide complex A-5", "brain bioregulator", "cognition / memory & attention", "mental capacity maintenance in aging", "neuroprotection (discussed)", "longevity / khavinson cytomax courses", "post-stroke residual symptoms (historical clinical add-on)", "long-term tbi / craniocerebral injury sequelae (historical clinical add-on)" ], "feel_search": [ "cognition / memory & attention", "mental capacity maintenance in aging", "neuroprotection (discussed)", "longevity / khavinson cytomax courses", "post-stroke residual symptoms (historical clinical add-on)", "long-term tbi / craniocerebral injury sequelae (historical clinical add-on)" ], "summary": "Cerluten is an animal cerebral-cortex peptide complex sold mainly in capsules as a brain bioregulator.", "search_blob": "cerluten cerluten brain bioregulator brain peptide complex cerluten\u00ae a-5 cytomax a-5 peptide complex a-5 cns peptide bioregulator nerve cell peptides (marketing) nature\u2019s marvels cns / central nervous system bioregulator (related product line) lingual cerluten (sublingual form discussed) cerluten cerluten\u00ae a-5 cytomax a-5 peptide complex a-5 brain bioregulator cognition / memory & attention mental capacity maintenance in aging neuroprotection (discussed) longevity / khavinson cytomax courses post-stroke residual symptoms (historical clinical add-on) long-term tbi / craniocerebral injury sequelae (historical clinical add-on) cognition longevity cognition / memory & attention mental capacity maintenance in aging neuroprotection (discussed) longevity / khavinson cytomax courses post-stroke residual symptoms (historical clinical add-on) long-term tbi / craniocerebral injury sequelae (historical clinical add-on) vascular encephalopathy support talk stress resilience / emotional stability (discussed) sleep quality (secondary discussion) headache and mental fatigue burden (subjective clinical series) healthy aging brain support stacks cognition / memory & attention mental capacity maintenance in aging neuroprotection (discussed) longevity / khavinson cytomax courses post-stroke residual symptoms (historical clinical add-on) long-term tbi / craniocerebral injury sequelae (historical clinical add-on) cerluten is an animal cerebral-cortex peptide complex sold mainly in capsules as a brain bioregulator. the inspected cognition post lists claimed mechanisms. it does not describe a cerluten course, personal benefit or adverse-effect timeline. cerluten is an oral peptide people look up for cognition. subtle clarity / less fog talk if anything \u2014 not stimulation or same-day focus drugs. not a stimulant, not an fda-approved alzheimer\u2019s / stroke / tbi drug, not cortexin itself, not cerebrolysin, not pinealon, not cortagen, not epitalon. longevity & bioregulators peptide systemic whole-body \u2014 people treat this as circulating, not a local pin. systemic whole-body circulating", "legal_class": null }, { "id": 108, "slug": "bronchogen", "name": "Bronchogen", "aliases": [ "respiratory bioregulator", "AEDL peptide", "AEDL", "Ala-Glu-Asp-Leu", "H-Ala-Glu-Asp-Leu-OH / H-AEDL-OH", "ADEL / Ala-Asp-Glu-Leu (letter-order in some peer-reviewed titles)", "peptide AEDL", "bronchial bioregulator", "lung bioregulator (Khavinson tetrapeptide)", "Khavinson bronchial tetrapeptide", "Bronchogen (Cytomax / cytogen capsule discussions)", "bronchial mucosa tetrapeptide" ], "type": "Peptide", "category": "Longevity & bioregulators", "goals_use_cases": [ "respiratory discussion", "immune", "lung & bronchial tissue research interest", "COPD / chronic airway research interest (preclinical framing)", "chronic bronchitis / smoker\u2013pollution narratives", "post-infection / post-viral / post-COVID recovery narratives", "asthma adjunct talk (not a rescue agent)", "immune (local mucosal / sIgA discussion)", "anti-inflammatory discussion (airway / neutrophilic)", "longevity / tissue bioregulation / geroprotection talk", "epithelial repair & mucociliary support (preclinical framing)", "surfactant / alveolar support discussion (preclinical framing)", "pulmonary fibrosis model interest (sparse preclinical)", "performance continuity (breathing comfort talk)", "organ-bioregulator multi-course calendars" ], "delivery_methods": [ "oral", "injection discussion" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "bronchogen", "AEDL", "Ala-Glu-Asp-Leu", "H-Ala-Glu-Asp-Leu-OH / H-AEDL-OH", "ADEL / Ala-Asp-Glu-Leu (letter-order in some peer-reviewed titles)", "peptide AEDL", "respiratory discussion", "lung & bronchial tissue research interest", "copd / chronic airway research interest (preclinical framing)", "chronic bronchitis / smoker\u2013pollution narratives", "post-infection / post-viral / post-covid recovery narratives", "asthma adjunct talk (not a rescue agent)" ], "feel_search": [ "respiratory discussion", "lung & bronchial tissue research interest", "copd / chronic airway research interest (preclinical framing)", "chronic bronchitis / smoker\u2013pollution narratives", "post-infection / post-viral / post-covid recovery narratives", "asthma adjunct talk (not a rescue agent)" ], "summary": "Bronchogen is the synthetic tetrapeptide AEDL, marketed as a lung bioregulator and studied mainly in preclinical respiratory research.", "search_blob": "bronchogen bronchogen respiratory bioregulator aedl peptide aedl ala-glu-asp-leu h-ala-glu-asp-leu-oh / h-aedl-oh adel / ala-asp-glu-leu (letter-order in some peer-reviewed titles) peptide aedl bronchial bioregulator lung bioregulator (khavinson tetrapeptide) khavinson bronchial tetrapeptide bronchogen (cytomax / cytogen capsule discussions) bronchial mucosa tetrapeptide bronchogen aedl ala-glu-asp-leu h-ala-glu-asp-leu-oh / h-aedl-oh adel / ala-asp-glu-leu (letter-order in some peer-reviewed titles) peptide aedl respiratory discussion lung & bronchial tissue research interest copd / chronic airway research interest (preclinical framing) chronic bronchitis / smoker\u2013pollution narratives post-infection / post-viral / post-covid recovery narratives asthma adjunct talk (not a rescue agent) respiratory discussion immune lung & bronchial tissue research interest copd / chronic airway research interest (preclinical framing) chronic bronchitis / smoker\u2013pollution narratives post-infection / post-viral / post-covid recovery narratives asthma adjunct talk (not a rescue agent) immune (local mucosal / siga discussion) anti-inflammatory discussion (airway / neutrophilic) longevity / tissue bioregulation / geroprotection talk epithelial repair & mucociliary support (preclinical framing) surfactant / alveolar support discussion (preclinical framing) pulmonary fibrosis model interest (sparse preclinical) performance continuity (breathing comfort talk) organ-bioregulator multi-course calendars respiratory discussion lung & bronchial tissue research interest copd / chronic airway research interest (preclinical framing) chronic bronchitis / smoker\u2013pollution narratives post-infection / post-viral / post-covid recovery narratives asthma adjunct talk (not a rescue agent) bronchogen is the synthetic tetrapeptide aedl, marketed as a lung bioregulator and studied mainly in preclinical respiratory research. one self-test reports improved peak-flow readings across two courses but did no cardio testing. home spirometry and an uncontrolled design limit the conclusion. bronchogen is a peptide people look up for immune support. active window in short 10\u201320 day community models; still mostly subtle or null. not a rescue inhaler, steroid substitute, antibiotic/antiviral, mucolytic, oxygen replacement, or proven copd/asthma disease-modifying drug. longevity & bioregulators peptide systemic whole-body \u2014 people treat this as circulating, not a local pin. systemic whole-body circulating", "legal_class": null }, { "id": 109, "slug": "chonluten", "name": "Chonluten", "aliases": [ "lung bioregulator", "EDG peptide", "Glu-Asp-Gly", "Glutamyl-aspartyl-glycine", "H-Glu-Asp-Gly-OH", "T-34", "T-34 tripeptide", "T34", "bronchial bioregulator", "Honluten", "Khonluten", "Chonluten Cytogen", "Chonluten (Cytomax / bioregulator capsule discussions)", "Khavinson lung peptide", "bronchopulmonary bioregulator" ], "type": "Peptide", "category": "Longevity & bioregulators", "goals_use_cases": [ "respiratory discussion", "lung / bronchial support (discussed)", "COPD / chronic bronchitis adjunct talk", "asthma / bronchial hyperreactivity adjunct talk", "post-viral / post-COVID recovery narratives", "smoking / vaping residual irritation talk", "mucosal / epithelial support (discussed)", "inflammation modulation (preclinical framing)", "longevity / organ-bioregulator calendars", "exercise breathing comfort / aerobic-capacity lore (weak)", "immune modulation (monocyte/macrophage in-vitro framing)", "GI mucosal secondary talk (developer literature)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "chonluten", "EDG peptide", "Glu-Asp-Gly", "Glutamyl-aspartyl-glycine", "H-Glu-Asp-Gly-OH", "T-34", "respiratory discussion", "lung / bronchial support (discussed)", "copd / chronic bronchitis adjunct talk", "asthma / bronchial hyperreactivity adjunct talk", "post-viral / post-covid recovery narratives", "smoking / vaping residual irritation talk" ], "feel_search": [ "respiratory discussion", "lung / bronchial support (discussed)", "copd / chronic bronchitis adjunct talk", "asthma / bronchial hyperreactivity adjunct talk", "post-viral / post-covid recovery narratives", "smoking / vaping residual irritation talk" ], "summary": "Chonluten is the synthetic tripeptide EDG, marketed as a bronchopulmonary bioregulator for lung and breathing concerns.", "search_blob": "chonluten chonluten lung bioregulator edg peptide glu-asp-gly glutamyl-aspartyl-glycine h-glu-asp-gly-oh t-34 t-34 tripeptide t34 bronchial bioregulator honluten khonluten chonluten cytogen chonluten (cytomax / bioregulator capsule discussions) khavinson lung peptide bronchopulmonary bioregulator chonluten edg peptide glu-asp-gly glutamyl-aspartyl-glycine h-glu-asp-gly-oh t-34 respiratory discussion lung / bronchial support (discussed) copd / chronic bronchitis adjunct talk asthma / bronchial hyperreactivity adjunct talk post-viral / post-covid recovery narratives smoking / vaping residual irritation talk respiratory discussion lung / bronchial support (discussed) copd / chronic bronchitis adjunct talk asthma / bronchial hyperreactivity adjunct talk post-viral / post-covid recovery narratives smoking / vaping residual irritation talk mucosal / epithelial support (discussed) inflammation modulation (preclinical framing) longevity / organ-bioregulator calendars exercise breathing comfort / aerobic-capacity lore (weak) immune modulation (monocyte/macrophage in-vitro framing) gi mucosal secondary talk (developer literature) respiratory discussion lung / bronchial support (discussed) copd / chronic bronchitis adjunct talk asthma / bronchial hyperreactivity adjunct talk post-viral / post-covid recovery narratives smoking / vaping residual irritation talk chonluten is the synthetic tripeptide edg, marketed as a bronchopulmonary bioregulator for lung and breathing concerns. a four-week chonluten/bronchogen account describes easier deep breaths and less nighttime coughing, with occasional breathlessness still present. chonluten is a peptide people look up for recovery. many report no detectable change after 1\u20132 courses. longevity & bioregulators peptide systemic whole-body \u2014 people treat this as circulating, not a local pin. systemic whole-body circulating", "legal_class": null }, { "id": 110, "slug": "crystagen", "name": "Crystagen", "aliases": [ "immune bioregulator", "EAD peptide", "EDP peptide", "Glu-Asp-Pro", "EDP tripeptide", "Khavinson immune cytogen", "Crystagen\u00ae (commercial bioregulator branding)", "Kristagen", "T-38 (designation in some originator/vendor lists)", "AC-6 (coded Glu-Asp-Pro in some bioregulator catalogs)", "thymus/immune short peptide bioregulator", "EDG peptide (conflicting vendor sequence claim \u2014 see sequence uncertainty)", "EAD peptide (search misspelling / informal shorthand)", "Glu-Asp-Gly (alternate vendor sequence discussions; often mapped to Chonluten in originator tissue-pair schemes)" ], "type": "Peptide", "category": "Longevity & bioregulators", "goals_use_cases": [ "immune", "immune modulation / immunosenescence (discussed)", "thymus support / thymic epithelial framing (preclinical)", "B-cell and T-cell balance narratives", "longevity / multi-bioregulator calendars", "post-illness or high-load recovery continuity (community)", "seasonal resilience talk", "cellular aging / gene-expression research (originator model)", "post-stress or athletic immune-normalization talk (originator summaries)", "not acute antiviral replacement or infection treatment" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "crystagen", "EDP peptide", "Glu-Asp-Pro", "EDP tripeptide", "immune bioregulator", "Khavinson immune cytogen", "immune modulation / immunosenescence (discussed)", "thymus support / thymic epithelial framing (preclinical)", "b-cell and t-cell balance narratives", "longevity / multi-bioregulator calendars", "post-illness or high-load recovery continuity (community)", "seasonal resilience talk" ], "feel_search": [ "immune modulation / immunosenescence (discussed)", "thymus support / thymic epithelial framing (preclinical)", "b-cell and t-cell balance narratives", "longevity / multi-bioregulator calendars", "post-illness or high-load recovery continuity (community)", "seasonal resilience talk" ], "summary": "Crystagen is the synthetic tripeptide EDP, marketed for immune or thymus support; similarly named products need sequence checks.", "search_blob": "crystagen crystagen immune bioregulator ead peptide edp peptide glu-asp-pro edp tripeptide khavinson immune cytogen crystagen\u00ae (commercial bioregulator branding) kristagen t-38 (designation in some originator/vendor lists) ac-6 (coded glu-asp-pro in some bioregulator catalogs) thymus/immune short peptide bioregulator edg peptide (conflicting vendor sequence claim \u2014 see sequence uncertainty) ead peptide (search misspelling / informal shorthand) glu-asp-gly (alternate vendor sequence discussions; often mapped to chonluten in originator tissue-pair schemes) crystagen edp peptide glu-asp-pro edp tripeptide immune bioregulator khavinson immune cytogen immune modulation / immunosenescence (discussed) thymus support / thymic epithelial framing (preclinical) b-cell and t-cell balance narratives longevity / multi-bioregulator calendars post-illness or high-load recovery continuity (community) seasonal resilience talk immune immune modulation / immunosenescence (discussed) thymus support / thymic epithelial framing (preclinical) b-cell and t-cell balance narratives longevity / multi-bioregulator calendars post-illness or high-load recovery continuity (community) seasonal resilience talk cellular aging / gene-expression research (originator model) post-stress or athletic immune-normalization talk (originator summaries) not acute antiviral replacement or infection treatment immune modulation / immunosenescence (discussed) thymus support / thymic epithelial framing (preclinical) b-cell and t-cell balance narratives longevity / multi-bioregulator calendars post-illness or high-load recovery continuity (community) seasonal resilience talk crystagen is the synthetic tripeptide edp, marketed for immune or thymus support; similarly named products need sequence checks. an enthusiastic long-term peptide user gives no specific immune endpoint. a separate multi-peptide experiment found no significant lymphocyte change at its two-month retest. crystagen is a peptide people look up for immune support. some claim steadier baseline energy or fewer \u201con the edge of a cold\u201d days\u2014causality weak without exposure tracking. longevity & bioregulators peptide systemic systemic immune/thymus bioregulator framing; not a local soft-tissue or injury-site injection. systemic whole-body circulating", "legal_class": null }, { "id": 111, "slug": "cortagen", "name": "Cortagen", "aliases": [ "AEDP peptide", "cortex bioregulator", "AEDP", "Ala-Glu-Asp-Pro", "H-Ala-Glu-Asp-Pro-OH", "AEDP tetrapeptide", "Cortagen peptide", "cortex tetrapeptide", "cerebral-cortex tetrapeptide", "Khavinson Cortagen", "Cortexin synthetic analog (AEDP)", "SCHEMBL5491754 (database synonym, vendor listings)" ], "type": "Peptide", "category": "Longevity & bioregulators", "goals_use_cases": [ "cognition", "stress", "cognition / focus baseline (community)", "brain fog / mental stamina (discussed)", "stress load composure (anecdotal)", "neuroprotection interest (preclinical + community)", "peripheral nerve recovery talk (entrapment, post-surgical; animal-driven)", "post-concussion / TBI-adjunct interest (community + extract-era halo)", "longevity / Khavinson bioregulator rotation", "aging-brain support narratives", "on-cycle cortical buffer talk (AAS or heavy stims \u2014 unproven)", "vs Cortexin / Pinealon / Epitalon search adjacency" ], "delivery_methods": [ "injection discussion", "oral" ], "discussion_popularity": "Emerging", "reach": "Mixed", "misspellings_search_terms": [ "cortagen", "AEDP", "Ala-Glu-Asp-Pro", "H-Ala-Glu-Asp-Pro-OH", "AEDP peptide", "AEDP tetrapeptide", "cognition / focus baseline (community)", "brain fog / mental stamina (discussed)", "stress load composure (anecdotal)", "neuroprotection interest (preclinical + community)", "peripheral nerve recovery talk (entrapment, post-surgical; animal-driven)", "post-concussion / tbi-adjunct interest (community + extract-era halo)" ], "feel_search": [ "cognition / focus baseline (community)", "brain fog / mental stamina (discussed)", "stress load composure (anecdotal)", "neuroprotection interest (preclinical + community)", "peripheral nerve recovery talk (entrapment, post-surgical; animal-driven)", "post-concussion / tbi-adjunct interest (community + extract-era halo)" ], "summary": "Cortagen is the synthetic tetrapeptide AEDP, developed from cortex-extract research and marketed as a nervous-system bioregulator.", "search_blob": "cortagen cortagen aedp peptide cortex bioregulator aedp ala-glu-asp-pro h-ala-glu-asp-pro-oh aedp tetrapeptide cortagen peptide cortex tetrapeptide cerebral-cortex tetrapeptide khavinson cortagen cortexin synthetic analog (aedp) schembl5491754 (database synonym, vendor listings) cortagen aedp ala-glu-asp-pro h-ala-glu-asp-pro-oh aedp peptide aedp tetrapeptide cognition / focus baseline (community) brain fog / mental stamina (discussed) stress load composure (anecdotal) neuroprotection interest (preclinical + community) peripheral nerve recovery talk (entrapment, post-surgical; animal-driven) post-concussion / tbi-adjunct interest (community + extract-era halo) cognition stress cognition / focus baseline (community) brain fog / mental stamina (discussed) stress load composure (anecdotal) neuroprotection interest (preclinical + community) peripheral nerve recovery talk (entrapment, post-surgical; animal-driven) post-concussion / tbi-adjunct interest (community + extract-era halo) longevity / khavinson bioregulator rotation aging-brain support narratives on-cycle cortical buffer talk (aas or heavy stims \u2014 unproven) vs cortexin / pinealon / epitalon search adjacency cognition / focus baseline (community) brain fog / mental stamina (discussed) stress load composure (anecdotal) neuroprotection interest (preclinical + community) peripheral nerve recovery talk (entrapment, post-surgical; animal-driven) post-concussion / tbi-adjunct interest (community + extract-era halo) cortagen is the synthetic tetrapeptide aedp, developed from cortex-extract research and marketed as a nervous-system bioregulator. one first-use account describes sleeping all night and half the day. the visible discussion does not supply a later cognitive-benefit result. cortagen is a peptide for cognition. first subtle clarity, stress-load composure, or \u201cnothing yet\u201d notes; community cognitive talk often clusters mid-course rather than day one. longevity & bioregulators peptide mixed mixed \u2014 cortex/cns- and nerve-framed synthetic aedp; community short courses are systemic, not local injury-site dosing or cortexin extract. mixed local systemic", "legal_class": null }, { "id": 112, "slug": "pnc-27", "name": "PNC-27", "aliases": [ "PNC27", "p53-HDM2 related peptide discussion", "PNC 27", "p53-HDM-2 membrane peptide (discussion label)", "chimeric p53-penetratin peptide", "p53 residues 12\u201326 + MRP / penetratin peptide", "OM-301 (Oncolyze lead candidate; previously discussed as PNC-27 lineage)", "HY-P3508 (catalog-style ID on some lab suppliers)" ], "type": "Peptide", "category": "Experimental oncology-adjacent peptides", "goals_use_cases": [ "experimental oncology discussion", "experimental oncology / selective cancer-cell kill discussion", "membrane HDM-2 / MDM2 targeting research", "AML and leukemia stem-cell preclinical interest", "solid-tumor line research (pancreas, breast, ovary, colon, cervix, lung, melanoma, etc.)", "chemo-resistant / cancer-stem-cell ex vivo discussion", "pore-forming (\u201cpoptosis\u201d / membranolysis) mechanism research", "comparison with shorter analog PNC-28 and inactive control PNC-29", "research-only investigational use \u2014 not approved cancer therapy" ], "delivery_methods": [ "research use discussion only" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "pnc-27", "pnc 27", "pnc27", "p53-HDM-2 membrane peptide (discussion label)", "chimeric p53-penetratin peptide", "p53 residues 12\u201326 + MRP / penetratin peptide", "experimental oncology / selective cancer-cell kill discussion", "membrane hdm-2 / mdm2 targeting research", "aml and leukemia stem-cell preclinical interest", "solid-tumor line research (pancreas, breast, ovary, colon, cervix, lung, melanoma, etc.)", "chemo-resistant / cancer-stem-cell ex vivo discussion", "pore-forming (\u201cpoptosis\u201d / membranolysis) mechanism research" ], "feel_search": [ "experimental oncology / selective cancer-cell kill discussion", "membrane hdm-2 / mdm2 targeting research", "aml and leukemia stem-cell preclinical interest", "solid-tumor line research (pancreas, breast, ovary, colon, cervix, lung, melanoma, etc.)", "chemo-resistant / cancer-stem-cell ex vivo discussion", "pore-forming (\u201cpoptosis\u201d / membranolysis) mechanism research" ], "summary": "PNC-27 is a synthetic peptide combining a p53-related segment with a cell-penetrating segment for experimental cancer research.", "search_blob": "pnc-27 pnc-27 pnc27 p53-hdm2 related peptide discussion pnc 27 p53-hdm-2 membrane peptide (discussion label) chimeric p53-penetratin peptide p53 residues 12\u201326 + mrp / penetratin peptide om-301 (oncolyze lead candidate; previously discussed as pnc-27 lineage) hy-p3508 (catalog-style id on some lab suppliers) pnc-27 pnc 27 pnc27 p53-hdm-2 membrane peptide (discussion label) chimeric p53-penetratin peptide p53 residues 12\u201326 + mrp / penetratin peptide experimental oncology / selective cancer-cell kill discussion membrane hdm-2 / mdm2 targeting research aml and leukemia stem-cell preclinical interest solid-tumor line research (pancreas, breast, ovary, colon, cervix, lung, melanoma, etc.) chemo-resistant / cancer-stem-cell ex vivo discussion pore-forming (\u201cpoptosis\u201d / membranolysis) mechanism research experimental oncology discussion experimental oncology / selective cancer-cell kill discussion membrane hdm-2 / mdm2 targeting research aml and leukemia stem-cell preclinical interest solid-tumor line research (pancreas, breast, ovary, colon, cervix, lung, melanoma, etc.) chemo-resistant / cancer-stem-cell ex vivo discussion pore-forming (\u201cpoptosis\u201d / membranolysis) mechanism research comparison with shorter analog pnc-28 and inactive control pnc-29 research-only investigational use \u2014 not approved cancer therapy experimental oncology / selective cancer-cell kill discussion membrane hdm-2 / mdm2 targeting research aml and leukemia stem-cell preclinical interest solid-tumor line research (pancreas, breast, ovary, colon, cervix, lung, melanoma, etc.) chemo-resistant / cancer-stem-cell ex vivo discussion pore-forming (\u201cpoptosis\u201d / membranolysis) mechanism research pnc-27 is a synthetic peptide combining a p53-related segment with a cell-penetrating segment for experimental cancer research. one self-experimenter first mentioned dizziness and fatigue, then said early changes may be unrelated and noticed little after about three weeks. pnc-27 is a peptide people look up for experimental cancer research. social/patient-group posts asking \u201chas anyone tried it\u201d exist; controlled human outcome data do not. experimental oncology-adjacent peptides peptide systemic whole-body exposure is discussed; intratumoral reports focus on local concentration. systemic whole-body circulating", "legal_class": null }, { "id": 113, "slug": "ghrh-1-44", "name": "GHRH (1-44)", "aliases": [ "somatorelin", "growth hormone releasing hormone", "Somatorelin", "Growth hormone\u2013releasing hormone (1-44)", "hGHRH(1-44)", "hGHRH(1-44)NH2", "GHRH-1,44-amide", "GRF (1-44)", "Growth hormone\u2013releasing factor (1-44)", "Somatocrinin (endogenous form discussions)", "GHRH 1-44 amide", "somatotropin releasing hormone (1-44)amide", "Full-length GHRH" ], "type": "Peptide", "category": "Growth hormone axis", "goals_use_cases": [ "muscle growth", "diagnostics adjacency", "anti-aging discussion", "recovery", "body composition (discussed)", "visceral fat (clinical signal)", "sleep (GH-axis adjacency)", "performance", "longevity (discussed)", "IGF-1 support (discussed)", "age-related GH decline discussion" ], "delivery_methods": [ "injection" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "ghrh-1-44", "ghrh 1 44", "ghrh144", "GHRH (1-44)", "ghrh-(1-44)", "Somatorelin", "muscle growth", "diagnostics adjacency", "anti-aging discussion", "recovery", "body composition (discussed)", "visceral fat (clinical signal)" ], "feel_search": [ "muscle growth", "diagnostics adjacency", "anti-aging discussion", "recovery", "body composition (discussed)", "visceral fat (clinical signal)" ], "summary": "GHRH(1-44), or somatorelin, is the full-length hormone that tells the pituitary to release growth hormone; it differs from sermorelin and CJC analogs.", "search_blob": "ghrh (1-44) ghrh-1-44 somatorelin growth hormone releasing hormone somatorelin growth hormone\u2013releasing hormone (1-44) hghrh(1-44) hghrh(1-44)nh2 ghrh-1,44-amide grf (1-44) growth hormone\u2013releasing factor (1-44) somatocrinin (endogenous form discussions) ghrh 1-44 amide somatotropin releasing hormone (1-44)amide full-length ghrh ghrh-1-44 ghrh 1 44 ghrh144 ghrh (1-44) ghrh-(1-44) somatorelin muscle growth diagnostics adjacency anti-aging discussion recovery body composition (discussed) visceral fat (clinical signal) muscle growth diagnostics adjacency anti-aging discussion recovery body composition (discussed) visceral fat (clinical signal) sleep (gh-axis adjacency) performance longevity (discussed) igf-1 support (discussed) age-related gh decline discussion muscle growth diagnostics adjacency anti-aging discussion recovery body composition (discussed) visceral fat (clinical signal) ghrh(1-44), or somatorelin, is the full-length hormone that tells the pituitary to release growth hormone; it differs from sermorelin and cjc analogs. ghrh (1-44) is a peptide people look up for muscle. few logs isolate unmodified 1\u201344 from sermorelin / cjc / tesamorelin. growth hormone axis peptide systemic systemic \u2014 binds pituitary ghrh receptors and raises endogenous gh pulses (then igf-1); not a local repair or site-specific fat-dissolve peptide. systemic whole-body circulating", "legal_class": null }, { "id": 114, "slug": "tesamorelin-analogs-discussion", "name": "GHRH analogs (clinic-compounded class discussion)", "aliases": [ "compounded GHRH", "GHRH blends", "Tesamorelin class discussion", "GHRH analogs", "Egrifta (brand reference)", "tesamorelin research discussion", "tesamorelin vs sermorelin vs CJC", "GHRH peptide class", "growth hormone releasing hormone analogs", "clinic GHRH stack talk" ], "type": "Peptide", "category": "Growth hormone axis", "goals_use_cases": [ "fat loss", "recovery", "anti-aging discussion", "visceral fat reduction (discussed)", "trunk / midsection aesthetics", "body composition", "lean mass preservation (discussed)", "liver fat / metabolic talk", "sleep (sermorelin / CJC-ipa adjacency)", "IGF-1 support (discussed)", "performance continuity", "GH-axis alternative to exogenous HGH" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "tesamorelin-analogs-discussion", "tesamorelin analogs discussion", "tesamorelinanalogsdiscussion", "GHRH analogs (clinic-compounded class discussion)", "ghrh-analogs-(clinic-compounded-class-discussion)", "Tesamorelin class discussion", "fat loss", "visceral fat reduction (discussed)", "trunk / midsection aesthetics", "recovery", "anti-aging discussion", "body composition" ], "feel_search": [ "fat loss", "visceral fat reduction (discussed)", "trunk / midsection aesthetics", "recovery", "anti-aging discussion", "body composition" ], "summary": "GHRH analogues are peptides that stimulate pituitary growth-hormone release; this class includes distinct products, not one interchangeable blend.", "search_blob": "ghrh analogs (clinic-compounded class discussion) tesamorelin-analogs-discussion compounded ghrh ghrh blends tesamorelin class discussion ghrh analogs egrifta (brand reference) tesamorelin research discussion tesamorelin vs sermorelin vs cjc ghrh peptide class growth hormone releasing hormone analogs clinic ghrh stack talk tesamorelin-analogs-discussion tesamorelin analogs discussion tesamorelinanalogsdiscussion ghrh analogs (clinic-compounded class discussion) ghrh-analogs-(clinic-compounded-class-discussion) tesamorelin class discussion fat loss visceral fat reduction (discussed) trunk / midsection aesthetics recovery anti-aging discussion body composition fat loss recovery anti-aging discussion visceral fat reduction (discussed) trunk / midsection aesthetics body composition lean mass preservation (discussed) liver fat / metabolic talk sleep (sermorelin / cjc-ipa adjacency) igf-1 support (discussed) performance continuity gh-axis alternative to exogenous hgh fat loss visceral fat reduction (discussed) trunk / midsection aesthetics recovery anti-aging discussion body composition ghrh analogues are peptides that stimulate pituitary growth-hormone release; this class includes distinct products, not one interchangeable blend. tesamorelin users describe mixed waist changes and water retention; the inspected thread does not establish an effect for unnamed analogs. ghrh analogs (clinic-compounded class discussion) is a peptide people look up for fat loss. scale weight can look almost flat while ct/mri vat improves. growth hormone axis peptide systemic systemic \u2014 pituitary ghrh-receptor stimulation \u2192 endogenous gh pulses \u2192 hepatic igf-1 and whole-body composition effects. systemic whole-body circulating", "legal_class": null }, { "id": 115, "slug": "selank-tp7-variants", "name": "Selank analogs / TP-7 variants", "aliases": [ "TP7 variants", "selank family", "TP-7", "Selank family", "Selank (TP-7)", "Selanc", "\u0421\u0435\u043b\u0430\u043d\u043a", "Thr-Lys-Pro-Arg-Pro-Gly-Pro family", "TKPRPGP family", "N-Acetyl Selank", "N-Acetyl Selank Amidate", "NA-Selank / NA-Selank Amidate", "Ac-Thr-Lys-Pro-Arg-Pro-Gly-Pro-NH2 (dual-capped form)", "tuftsin + Pro-Gly-Pro heptapeptide family" ], "type": "Peptide", "category": "Cognitive / nootropic peptides", "goals_use_cases": [ "anxiety discussion", "cognition", "anxiety discussion (GAD / generalized anxiety / baseline edge)", "calm focus without heavy sedation", "cognition under stress", "mood smoothing / emotional reactivity", "stress resilience / neurasthenia-style fatigue talk", "social / performance / exam anxiety talk", "nootropic stacks (esp. with Semax family)", "immune-adjacent discussion (tuftsin heritage, secondary)", "sleep balance (discussed; mixed)", "variant hunt: plain vs N-acetyl vs dual-capped amidate stability claims" ], "delivery_methods": [ "nasal" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "selank-tp7-variants", "selank tp7 variants", "selanktp7variants", "Selank analogs / TP-7 variants", "selank-analogs-/-tp-7-variants", "TP-7", "anxiety discussion (gad / generalized anxiety / baseline edge)", "calm focus without heavy sedation", "cognition under stress", "mood smoothing / emotional reactivity", "stress resilience / neurasthenia-style fatigue talk", "social / performance / exam anxiety talk" ], "feel_search": [ "anxiety discussion (gad / generalized anxiety / baseline edge)", "calm focus without heavy sedation", "cognition under stress", "mood smoothing / emotional reactivity", "stress resilience / neurasthenia-style fatigue talk", "social / performance / exam anxiety talk" ], "summary": "This family covers Selank/TP-7-related synthetic peptides discussed for anxiety; altered variants should not inherit the parent peptide's evidence.", "search_blob": "selank analogs / tp-7 variants selank-tp7-variants tp7 variants selank family tp-7 selank family selank (tp-7) selanc \u0441\u0435\u043b\u0430\u043d\u043a thr-lys-pro-arg-pro-gly-pro family tkprpgp family n-acetyl selank n-acetyl selank amidate na-selank / na-selank amidate ac-thr-lys-pro-arg-pro-gly-pro-nh2 (dual-capped form) tuftsin + pro-gly-pro heptapeptide family selank-tp7-variants selank tp7 variants selanktp7variants selank analogs / tp-7 variants selank-analogs-/-tp-7-variants tp-7 anxiety discussion (gad / generalized anxiety / baseline edge) calm focus without heavy sedation cognition under stress mood smoothing / emotional reactivity stress resilience / neurasthenia-style fatigue talk social / performance / exam anxiety talk anxiety discussion cognition anxiety discussion (gad / generalized anxiety / baseline edge) calm focus without heavy sedation cognition under stress mood smoothing / emotional reactivity stress resilience / neurasthenia-style fatigue talk social / performance / exam anxiety talk nootropic stacks (esp. with semax family) immune-adjacent discussion (tuftsin heritage, secondary) sleep balance (discussed; mixed) variant hunt: plain vs n-acetyl vs dual-capped amidate stability claims anxiety discussion (gad / generalized anxiety / baseline edge) calm focus without heavy sedation cognition under stress mood smoothing / emotional reactivity stress resilience / neurasthenia-style fatigue talk social / performance / exam anxiety talk this family covers selank/tp-7-related synthetic peptides discussed for anxiety; altered variants should not inherit the parent peptide's evidence. reports include subtle calm or no benefit, but one n-acetyl selank user described markedly increased anxiety; formulations and co-use differ. selank analogs / tp-7 variants are a peptide family people look up for focus. steadier multi-day emotional reactivity and stress handling more than a single-dose buzz or euphoria. cognitive / nootropic peptides peptide systemic systemic cns family \u2014 nasal delivery dominates for whole-brain anxiolytic/nootropic talk, not local tissue repair. systemic whole-body circulating", "legal_class": null }, { "id": 116, "slug": "semax-variants", "name": "Semax family variants", "aliases": [ "Semax analogues", "Met-Semax discussion", "Semax analogs", "N-Acetyl Semax family", "NA-Semax / NASA family", "N-Acetyl Semax Amidate family", "ACTH(4-10) Semax-related peptides", "MEHFPGP variants", "Adamax (Semax-family discussion)", "Semax Amidate", "Ac-MEHFPGP / Ac-MEHFPGP-NH2" ], "type": "Peptide", "category": "Cognitive / nootropic peptides", "goals_use_cases": [ "cognition", "focus", "attention", "working memory (discussed)", "memory / learning support (discussed)", "neuroprotection discussion", "mental performance under stress", "mental stamina / deep-work endurance", "nootropic stacking (especially with Selank-class)", "mood (secondary discussion)", "exam / sprint cognitive support", "ADHD-adjacent focus talk (community only; not an approved indication)", "comparing plain vs capped research-chem forms" ], "delivery_methods": [ "nasal" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "semax-variants", "semax variants", "semaxvariants", "Semax family variants", "semax-family-variants", "Semax analogues", "cognition", "focus", "attention", "working memory (discussed)", "memory / learning support (discussed)", "neuroprotection discussion" ], "feel_search": [ "cognition", "focus", "attention", "working memory (discussed)", "memory / learning support (discussed)", "neuroprotection discussion" ], "summary": "Semax variants are modified ACTH-fragment peptides, including end-capped and adamantane-related versions sold for cognitive interests.", "search_blob": "semax family variants semax-variants semax analogues met-semax discussion semax analogs n-acetyl semax family na-semax / nasa family n-acetyl semax amidate family acth(4-10) semax-related peptides mehfpgp variants adamax (semax-family discussion) semax amidate ac-mehfpgp / ac-mehfpgp-nh2 semax-variants semax variants semaxvariants semax family variants semax-family-variants semax analogues cognition focus attention working memory (discussed) memory / learning support (discussed) neuroprotection discussion cognition focus attention working memory (discussed) memory / learning support (discussed) neuroprotection discussion mental performance under stress mental stamina / deep-work endurance nootropic stacking (especially with selank-class) mood (secondary discussion) exam / sprint cognitive support adhd-adjacent focus talk (community only; not an approved indication) comparing plain vs capped research-chem forms cognition focus attention working memory (discussed) memory / learning support (discussed) neuroprotection discussion semax variants are modified acth-fragment peptides, including end-capped and adamantane-related versions sold for cognitive interests. one n-acetyl-semax-amidate user described subtle focus initially, then little repeat effect when using a larger supplement stack. semax family variants is a peptide for cognition. cleaner task focus and less mental drift; often framed less jittery than caffeine megadoses or amphetamine-class stacks. cognitive / nootropic peptides peptide systemic brain-focused semax-family discussion, mainly intranasal; minority subq reports do not establish selective human tissue delivery. systemic whole-body circulating", "legal_class": null }, { "id": 117, "slug": "pt-141-nasal-research", "name": "PT-141 nasal research (bremelanotide routes)", "aliases": [ "PT-141 nasal research", "bremelanotide nasal", "PT-141 nasal spray", "intranasal PT-141", "intranasal bremelanotide", "PT141 nose spray", "PT-141 IN", "bremelanotide intranasal spray", "compounded PT-141 spray", "nasal Vyleesi (misnomer)" ], "type": "Peptide", "category": "Libido & melanocortin", "goals_use_cases": [ "libido", "libido / sexual desire (CNS melanocortin path, discussed)", "historical male ED research (intranasal PT-141 clinical program)", "PDE5 non-responder salvage talk (historical IN trials)", "needle-free delivery interest vs SC autoinjector or vial", "compounded clinic spray access (modern off-label discussion)", "CNS melanocortin (MC3/MC4) desire signaling research", "as-needed desire/arousal window before activity (discussed)", "route-debate: nasal absorption variability vs SC predictability", "stack with PDE5 for desire + erection (historical co-admin + community)" ], "delivery_methods": [ "nasal" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "pt-141-nasal-research", "pt 141 nasal research", "pt141nasalresearch", "PT-141 nasal research (bremelanotide routes)", "pt-141-nasal-research-(bremelanotide-routes)", "PT-141 nasal research", "libido / sexual desire (cns melanocortin path, discussed)", "historical male ed research (intranasal pt-141 clinical program)", "pde5 non-responder salvage talk (historical in trials)", "needle-free delivery interest vs sc autoinjector or vial", "compounded clinic spray access (modern off-label discussion)", "cns melanocortin (mc3/mc4) desire signaling research" ], "feel_search": [ "libido / sexual desire (cns melanocortin path, discussed)", "historical male ed research (intranasal pt-141 clinical program)", "pde5 non-responder salvage talk (historical in trials)", "needle-free delivery interest vs sc autoinjector or vial", "compounded clinic spray access (modern off-label discussion)", "cns melanocortin (mc3/mc4) desire signaling research" ], "summary": "PT-141 nasal research concerns intranasal bremelanotide, a melanocortin-receptor peptide; nasal products differ from the medical injection.", "search_blob": "pt-141 nasal research (bremelanotide routes) pt-141-nasal-research pt-141 nasal research bremelanotide nasal pt-141 nasal spray intranasal pt-141 intranasal bremelanotide pt141 nose spray pt-141 in bremelanotide intranasal spray compounded pt-141 spray nasal vyleesi (misnomer) pt-141-nasal-research pt 141 nasal research pt141nasalresearch pt-141 nasal research (bremelanotide routes) pt-141-nasal-research-(bremelanotide-routes) pt-141 nasal research libido / sexual desire (cns melanocortin path, discussed) historical male ed research (intranasal pt-141 clinical program) pde5 non-responder salvage talk (historical in trials) needle-free delivery interest vs sc autoinjector or vial compounded clinic spray access (modern off-label discussion) cns melanocortin (mc3/mc4) desire signaling research libido libido / sexual desire (cns melanocortin path, discussed) historical male ed research (intranasal pt-141 clinical program) pde5 non-responder salvage talk (historical in trials) needle-free delivery interest vs sc autoinjector or vial compounded clinic spray access (modern off-label discussion) cns melanocortin (mc3/mc4) desire signaling research as-needed desire/arousal window before activity (discussed) route-debate: nasal absorption variability vs sc predictability stack with pde5 for desire + erection (historical co-admin + community) libido / sexual desire (cns melanocortin path, discussed) historical male ed research (intranasal pt-141 clinical program) pde5 non-responder salvage talk (historical in trials) needle-free delivery interest vs sc autoinjector or vial compounded clinic spray access (modern off-label discussion) cns melanocortin (mc3/mc4) desire signaling research pt-141 nasal research concerns intranasal bremelanotide, a melanocortin-receptor peptide; nasal products differ from the medical injection. one nasal user described brief warmth, relaxation and sexual response; replies disputed the amount and reported no effect. pt-141 nasal research is a nasal peptide people look up for libido. earlier community notes describe several-hour same-day desire/arousal rather than a usual multi-day afterglow. libido & melanocortin peptide systemic systemic cns melanocortin (mc3r/mc4r) desire/arousal path \u2014 nasal is a delivery route debate, not a local genital drug. systemic whole-body circulating", "legal_class": null }, { "id": 118, "slug": "afamelanotide-community", "name": "Afamelanotide (community / implant access discussions)", "aliases": [ "Scenesse community talk", "implant MT-1 access discussion", "Afamelanotide implant", "Scenesse", "SCENESSE", "MT-1 implant discussion", "CUV1647", "NDP-MSH (implant context)", "Melanotan I (clinical form)", "afamelanotide 16 mg implant", "[Nle4,D-Phe7]-\u03b1-MSH implant" ], "type": "Peptide", "category": "Tanning & melanocortin", "goals_use_cases": [ "skin/hair", "photoprotection discussion", "tanning / pigmentation (expected implant effect)", "UV tolerance (EPP clinical context)", "access / specialty-drug logistics", "insurance / prior-auth discussion", "aesthetic skin-tone spillover talk (extrapolated, access-limited)", "vitiligo adjunct discussion (investigational implant + NB-UVB)", "other photodermatoses research interest (PMLE, solar urticaria)", "product-identity / counterfeit-vs-licensed implant debates" ], "delivery_methods": [ "implant" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "afamelanotide-community", "afamelanotide community", "afamelanotidecommunity", "Afamelanotide (community / implant access discussions)", "afamelanotide-(community-/-implant-access-discussions)", "Scenesse community talk", "skin/hair", "photoprotection discussion", "tanning / pigmentation (expected implant effect)", "uv tolerance (epp clinical context)", "access / specialty-drug logistics", "insurance / prior-auth discussion" ], "feel_search": [ "skin/hair", "photoprotection discussion", "tanning / pigmentation (expected implant effect)", "uv tolerance (epp clinical context)", "access / specialty-drug logistics", "insurance / prior-auth discussion" ], "summary": "Afamelanotide (Scenesse) is a controlled-release peptide implant used to improve light tolerance in adults with erythropoietic protoporphyria.", "search_blob": "afamelanotide (community / implant access discussions) afamelanotide-community scenesse community talk implant mt-1 access discussion afamelanotide implant scenesse scenesse mt-1 implant discussion cuv1647 ndp-msh (implant context) melanotan i (clinical form) afamelanotide 16 mg implant [nle4,d-phe7]-\u03b1-msh implant afamelanotide-community afamelanotide community afamelanotidecommunity afamelanotide (community / implant access discussions) afamelanotide-(community-/-implant-access-discussions) scenesse community talk skin/hair photoprotection discussion tanning / pigmentation (expected implant effect) uv tolerance (epp clinical context) access / specialty-drug logistics insurance / prior-auth discussion skin/hair photoprotection discussion tanning / pigmentation (expected implant effect) uv tolerance (epp clinical context) access / specialty-drug logistics insurance / prior-auth discussion aesthetic skin-tone spillover talk (extrapolated, access-limited) vitiligo adjunct discussion (investigational implant + nb-uvb) other photodermatoses research interest (pmle, solar urticaria) product-identity / counterfeit-vs-licensed implant debates skin/hair photoprotection discussion tanning / pigmentation (expected implant effect) uv tolerance (epp clinical context) access / specialty-drug logistics insurance / prior-auth discussion afamelanotide (scenesse) is a controlled-release peptide implant used to improve light tolerance in adults with erythropoietic protoporphyria. one epp patient describes a much easier two-hour hike nine days after an implant, but hot fingertips later that night. improved tolerance did not mean no symptoms. afamelanotide implant (scenesse) is a peptide people look up for daylight tolerance. base tan and freckle darkening become more obvious while epp light-protection habits continue. tanning & melanocortin peptide systemic systemic pigmentation signal; licensed scenesse is a clinician-inserted 16 mg subq implant, not a daily self-injected vial or nasal spray. systemic whole-body circulating", "legal_class": null }, { "id": 119, "slug": "setmelanotide", "name": "Setmelanotide", "aliases": [ "Imcivree", "RM-493", "IMCIVREE", "RM493", "Setmelanotide acetate", "setmelanotide SC" ], "type": "Peptide", "category": "Metabolic / melanocortin", "goals_use_cases": [ "fat loss", "rare obesity pathway discussion", "rare genetic obesity (POMC / PCSK1 / LEPR pathway)", "Bardet\u2013Biedl syndrome obesity / hyperphagia", "acquired hypothalamic obesity (approved / late-stage discussion by region)", "hyperphagia control (pathway-specific)", "appetite regulation via MC4R", "energy expenditure / REE discussion (early human chamber work)", "fat-loss narrative outside genetics (speculative / off-label talk only)", "MC4R pathway research", "comparison point vs GLP-1s and gray-market melanocortins" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "setmelanotide", "Imcivree", "RM-493", "RM493", "Setmelanotide acetate", "setmelanotide SC", "rare genetic obesity (pomc / pcsk1 / lepr pathway)", "bardet\u2013biedl syndrome obesity / hyperphagia", "acquired hypothalamic obesity (approved / late-stage discussion by region)", "hyperphagia control (pathway-specific)", "appetite regulation via mc4r", "energy expenditure / ree discussion (early human chamber work)" ], "feel_search": [ "rare genetic obesity (pomc / pcsk1 / lepr pathway)", "bardet\u2013biedl syndrome obesity / hyperphagia", "acquired hypothalamic obesity (approved / late-stage discussion by region)", "hyperphagia control (pathway-specific)", "appetite regulation via mc4r", "energy expenditure / ree discussion (early human chamber work)" ], "summary": "Setmelanotide is an MC4-receptor agonist peptide used for specified rare and hypothalamic forms of obesity, rather than general obesity.", "search_blob": "setmelanotide setmelanotide imcivree rm-493 imcivree rm493 setmelanotide acetate setmelanotide sc setmelanotide imcivree rm-493 rm493 setmelanotide acetate setmelanotide sc rare genetic obesity (pomc / pcsk1 / lepr pathway) bardet\u2013biedl syndrome obesity / hyperphagia acquired hypothalamic obesity (approved / late-stage discussion by region) hyperphagia control (pathway-specific) appetite regulation via mc4r energy expenditure / ree discussion (early human chamber work) fat loss rare obesity pathway discussion rare genetic obesity (pomc / pcsk1 / lepr pathway) bardet\u2013biedl syndrome obesity / hyperphagia acquired hypothalamic obesity (approved / late-stage discussion by region) hyperphagia control (pathway-specific) appetite regulation via mc4r energy expenditure / ree discussion (early human chamber work) fat-loss narrative outside genetics (speculative / off-label talk only) mc4r pathway research comparison point vs glp-1s and gray-market melanocortins rare genetic obesity (pomc / pcsk1 / lepr pathway) bardet\u2013biedl syndrome obesity / hyperphagia acquired hypothalamic obesity (approved / late-stage discussion by region) hyperphagia control (pathway-specific) appetite regulation via mc4r energy expenditure / ree discussion (early human chamber work) setmelanotide is an mc4-receptor agonist peptide used for specified rare and hypothalamic forms of obesity, rather than general obesity. a caregiver described less persistent food-seeking, alongside early fatigue, headaches and darker skin. setmelanotide is a peptide people look up for appetite. large relative drops in \u201cmost hunger\u201d / daily hunger scores. body-comp claims outside confirmed pathway disease remain speculation; this profile is research/education only, not a use protocol. metabolic / melanocortin peptide systemic systemic mc4r agonist for specific rare obesity indications; hunger-circuit treatment, not local repair or general aesthetic cutting. systemic whole-body circulating", "legal_class": null }, { "id": 120, "slug": "maridebart-cafraglutide", "name": "Maridebart cafraglutide", "aliases": [ "MariTide", "AMG 133 discussion", "AMG 133", "AMG-133", "AMG133", "maridebart cafraglutide", "MariTide (Amgen)", "GIPR antagonist / GLP-1 agonist conjugate", "GIPR-Ab + dual GLP-1 peptide conjugate", "peptide\u2013antibody conjugate obesity candidate", "monthly MariTide (pipeline shorthand)" ], "type": "Peptide", "category": "Metabolic / GLP-1 class", "goals_use_cases": [ "fat loss", "appetite control", "fat loss / chronic weight management (investigational)", "appetite control / satiety (GLP-1 arm)", "weight management with less-frequent injections than weekly incretins", "glycemic control in obesity + type 2 diabetes context", "cardiometabolic risk markers (waist, BP, hs-CRP, select lipids)", "maintenance / durability after large weight loss (Part 2 + Phase 3 framing)", "obesity-related outcomes pipeline interest (ASCVD, HF, OSA \u2014 Phase 3 talk)", "GIP-block vs GIP-agonist mechanism debate (vs tirzepatide)" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "maridebart-cafraglutide", "maridebart cafraglutide", "maridebartcafraglutide", "MariTide", "AMG 133", "AMG-133", "fat loss / chronic weight management (investigational)", "appetite control / satiety (glp-1 arm)", "weight management with less-frequent injections than weekly incretins", "glycemic control in obesity + type 2 diabetes context", "cardiometabolic risk markers (waist, bp, hs-crp, select lipids)", "maintenance / durability after large weight loss (part 2 + phase 3 framing)" ], "feel_search": [ "fat loss / chronic weight management (investigational)", "appetite control / satiety (glp-1 arm)", "weight management with less-frequent injections than weekly incretins", "glycemic control in obesity + type 2 diabetes context", "cardiometabolic risk markers (waist, bp, hs-crp, select lipids)", "maintenance / durability after large weight loss (part 2 + phase 3 framing)" ], "summary": "Maridebart cafraglutide (MariTide) is an investigational antibody\u2013peptide obesity treatment that activates GLP-1 receptors and blocks GIP receptors.", "search_blob": "maridebart cafraglutide maridebart-cafraglutide maritide amg 133 discussion amg 133 amg-133 amg133 maridebart cafraglutide maritide (amgen) gipr antagonist / glp-1 agonist conjugate gipr-ab + dual glp-1 peptide conjugate peptide\u2013antibody conjugate obesity candidate monthly maritide (pipeline shorthand) maridebart-cafraglutide maridebart cafraglutide maridebartcafraglutide maritide amg 133 amg-133 fat loss / chronic weight management (investigational) appetite control / satiety (glp-1 arm) weight management with less-frequent injections than weekly incretins glycemic control in obesity + type 2 diabetes context cardiometabolic risk markers (waist, bp, hs-crp, select lipids) maintenance / durability after large weight loss (part 2 + phase 3 framing) fat loss appetite control fat loss / chronic weight management (investigational) appetite control / satiety (glp-1 arm) weight management with less-frequent injections than weekly incretins glycemic control in obesity + type 2 diabetes context cardiometabolic risk markers (waist, bp, hs-crp, select lipids) maintenance / durability after large weight loss (part 2 + phase 3 framing) obesity-related outcomes pipeline interest (ascvd, hf, osa \u2014 phase 3 talk) gip-block vs gip-agonist mechanism debate (vs tirzepatide) fat loss / chronic weight management (investigational) appetite control / satiety (glp-1 arm) weight management with less-frequent injections than weekly incretins glycemic control in obesity + type 2 diabetes context cardiometabolic risk markers (waist, bp, hs-crp, select lipids) maintenance / durability after large weight loss (part 2 + phase 3 framing) maridebart cafraglutide (maritide) is an investigational antibody\u2013peptide obesity treatment that activates glp-1 receptors and blocks gip receptors. reduced appetite or weight can come with nausea, vomiting or constipation. early gi effects matter even with a monthly schedule; one claimed trial participant described persistent constipation. maridebart cafraglutide is an antibody people look up for fat loss. mechanism and frequency hype more than dense first-person logs. metabolic / glp-1 class peptide systemic systemic \u2014 a subcutaneous peptide\u2013antibody conjugate studied for appetite, weight, glycemic and cardiometabolic effects. systemic whole-body circulating", "legal_class": null }, { "id": 121, "slug": "vk2735", "name": "VK2735", "aliases": [ "Viking GLP-1/GIP discussion", "Viking VK2735", "VK-2735", "VKTX dual agonist", "Viking GLP-1/GIP dual agonist", "VENTURE VK2735", "VANQUISH VK2735", "Oral VK2735 / VK2735 tablet" ], "type": "Peptide", "category": "Metabolic / GLP-1 class", "goals_use_cases": [ "fat loss", "metabolic health", "fat loss / obesity weight management (primary clinical program)", "appetite regulation / food-noise reduction (class dual-agonist talk)", "metabolic / cardiometabolic risk-factor improvement (trial context)", "obesity with type 2 diabetes (VANQUISH-2 Phase 3 arm)", "oral incretin access without a different molecule than the injectable", "weight maintenance after induction (monthly SC / low-dose oral research)", "needle-averse or needle-fatigue dual-agonist interest", "pipeline comparison vs tirzepatide / retatrutide / oral GLP-1s", "performance continuity after large weight change (discussion only)", "research-chemical curiosity after Phase 2 headlines (sparse verified logs)" ], "delivery_methods": [ "subcutaneous", "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "vk2735", "Viking VK2735", "VK-2735", "VKTX dual agonist", "Viking GLP-1/GIP dual agonist", "VENTURE VK2735", "fat loss / obesity weight management (primary clinical program)", "appetite regulation / food-noise reduction (class dual-agonist talk)", "metabolic / cardiometabolic risk-factor improvement (trial context)", "obesity with type 2 diabetes (vanquish-2 phase 3 arm)", "oral incretin access without a different molecule than the injectable", "weight maintenance after induction (monthly sc / low-dose oral research)" ], "feel_search": [ "fat loss / obesity weight management (primary clinical program)", "appetite regulation / food-noise reduction (class dual-agonist talk)", "metabolic / cardiometabolic risk-factor improvement (trial context)", "obesity with type 2 diabetes (vanquish-2 phase 3 arm)", "oral incretin access without a different molecule than the injectable", "weight maintenance after induction (monthly sc / low-dose oral research)" ], "summary": "VK2735 is an investigational GLP-1/GIP receptor agonist peptide developed in injectable and oral formulations for weight management.", "search_blob": "vk2735 vk2735 viking glp-1/gip discussion viking vk2735 vk-2735 vktx dual agonist viking glp-1/gip dual agonist venture vk2735 vanquish vk2735 oral vk2735 / vk2735 tablet vk2735 viking vk2735 vk-2735 vktx dual agonist viking glp-1/gip dual agonist venture vk2735 fat loss / obesity weight management (primary clinical program) appetite regulation / food-noise reduction (class dual-agonist talk) metabolic / cardiometabolic risk-factor improvement (trial context) obesity with type 2 diabetes (vanquish-2 phase 3 arm) oral incretin access without a different molecule than the injectable weight maintenance after induction (monthly sc / low-dose oral research) fat loss metabolic health fat loss / obesity weight management (primary clinical program) appetite regulation / food-noise reduction (class dual-agonist talk) metabolic / cardiometabolic risk-factor improvement (trial context) obesity with type 2 diabetes (vanquish-2 phase 3 arm) oral incretin access without a different molecule than the injectable weight maintenance after induction (monthly sc / low-dose oral research) needle-averse or needle-fatigue dual-agonist interest pipeline comparison vs tirzepatide / retatrutide / oral glp-1s performance continuity after large weight change (discussion only) research-chemical curiosity after phase 2 headlines (sparse verified logs) fat loss / obesity weight management (primary clinical program) appetite regulation / food-noise reduction (class dual-agonist talk) metabolic / cardiometabolic risk-factor improvement (trial context) obesity with type 2 diabetes (vanquish-2 phase 3 arm) oral incretin access without a different molecule than the injectable weight maintenance after induction (monthly sc / low-dose oral research) vk2735 is an investigational glp-1/gip receptor agonist peptide developed in injectable and oral formulations for weight management. trial participants reported nausea and vomiting, usually mild or moderate; oral and injectable formulations had different study settings. vk2735 is a peptide people look up for fat loss. progressive scale change on weekly sc or daily oral; appetite drop typically precedes largest cumulative % loss. metabolic / glp-1 class peptide systemic systemic \u2014 dual glp-1/gip agonist developed as weekly subq and daily oral formulations for whole-body metabolic effects. systemic whole-body circulating", "legal_class": null }, { "id": 122, "slug": "eccn-agonist-class", "name": "Dual/triple agonist research class (non-reta)", "aliases": [ "multi-agonist peptides", "glucagon/GIP/GLP-1 class talk", "dual GLP-1/GIP agonists", "dual GLP-1/glucagon agonists", "triple agonist class (excluding retatrutide)", "incretin multi-agonists", "next-gen metabolic agonists", "dual/triple G agonists", "GIP/GLP-1 dual class", "GCG/GLP-1 dual class", "oxyntomodulin-analog duals", "multi-receptor incretin peptides" ], "type": "Peptide", "category": "Metabolic / GLP-1 class", "goals_use_cases": [ "fat loss", "metabolic health", "fat loss / chronic weight management", "appetite control / food-noise reduction", "glycemic control (T2D trial context)", "liver fat / MASLD discussion", "MASH / fibrosis research interest", "body composition (fat vs lean share discussion)", "obesity research (pipeline comparisons)", "cardiometabolic markers (waist, BP, lipids, liver enzymes)", "energy-expenditure narratives (glucagon arm)", "step-up after mono-GLP-1 plateau (community switch talk)", "visceral / organ fat reduction (imaging substudies)" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "eccn-agonist-class", "eccn agonist class", "eccnagonistclass", "Dual/triple agonist research class (non-reta)", "dual/triple-agonist-research-class-(non-reta)", "multi-agonist peptides", "fat loss / chronic weight management", "metabolic health", "appetite control / food-noise reduction", "glycemic control (t2d trial context)", "liver fat / masld discussion", "mash / fibrosis research interest" ], "feel_search": [ "fat loss / chronic weight management", "metabolic health", "appetite control / food-noise reduction", "glycemic control (t2d trial context)", "liver fat / masld discussion", "mash / fibrosis research interest" ], "summary": "This class groups dual and triple receptor peptides combining GLP-1 with GIP and/or glucagon activity for metabolic and weight-management research.", "search_blob": "dual/triple agonist research class (non-reta) eccn-agonist-class multi-agonist peptides glucagon/gip/glp-1 class talk dual glp-1/gip agonists dual glp-1/glucagon agonists triple agonist class (excluding retatrutide) incretin multi-agonists next-gen metabolic agonists dual/triple g agonists gip/glp-1 dual class gcg/glp-1 dual class oxyntomodulin-analog duals multi-receptor incretin peptides eccn-agonist-class eccn agonist class eccnagonistclass dual/triple agonist research class (non-reta) dual/triple-agonist-research-class-(non-reta) multi-agonist peptides fat loss / chronic weight management metabolic health appetite control / food-noise reduction glycemic control (t2d trial context) liver fat / masld discussion mash / fibrosis research interest fat loss metabolic health fat loss / chronic weight management appetite control / food-noise reduction glycemic control (t2d trial context) liver fat / masld discussion mash / fibrosis research interest body composition (fat vs lean share discussion) obesity research (pipeline comparisons) cardiometabolic markers (waist, bp, lipids, liver enzymes) energy-expenditure narratives (glucagon arm) step-up after mono-glp-1 plateau (community switch talk) visceral / organ fat reduction (imaging substudies) fat loss / chronic weight management metabolic health appetite control / food-noise reduction glycemic control (t2d trial context) liver fat / masld discussion mash / fibrosis research interest this class groups dual and triple receptor peptides combining glp-1 with gip and/or glucagon activity for metabolic and weight-management research. survodutide participants in one thread describe very different appetite and nausea patterns, including symptoms after increases. those reports are specific to that drug and trial. dual/triple agonist research class (non-reta) is a peptide people look up for fat loss. visceral and liver fat drops framed as organ-selective add-ons. metabolic / glp-1 class peptide systemic systemic multi-receptor metabolic peptides acting on appetite, glycemia, energy expenditure and hepatic fat; not local injury injects. systemic whole-body circulating", "legal_class": null }, { "id": 123, "slug": "5-amino-1mq-analogs", "name": "NNMT inhibitor class (beyond 5-Amino-1MQ)", "aliases": [ "NNMT inhibitors", "1MQ analogs", "5-Amino-1MQ analogs", "NNMTi class", "JBSNF-000088", "6-methoxynicotinamide", "JBSNF-000028", "JBSNF-000265", "MQ-scaffold NNMT inhibitors", "7-amino-1MQ", "2,3-diamino-1MQ", "1-methylquinolinium analogs", "nicotinamide N-methyltransferase inhibitors", "NAM-competitive NNMT inhibitors", "tricyclic NNMT inhibitors (Sanofi series)" ], "type": "Non-peptide", "category": "Metabolic research compounds", "goals_use_cases": [ "fat loss", "metabolic health", "body recomposition", "insulin sensitivity research (preclinical)", "NAD+ / methylation pathway discussion", "obesity research tools", "visceral adipose / white-fat NNMT narratives", "GLP-1 stack adjunct (community, mostly via parent compound)", "next-gen / alternate NNMTi curiosity after 5-Amino-1MQ hype", "muscle function / aged-muscle talk (parent scaffold; preclinical)", "diet-switch synergy narratives (preclinical NNMTi class)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "5-amino-1mq-analogs", "5 amino 1mq analogs", "5amino1mqanalogs", "NNMT inhibitor class (beyond 5-Amino-1MQ)", "nnmt-inhibitor-class-(beyond-5-amino-1mq)", "NNMT inhibitors", "fat loss", "metabolic health", "body recomposition", "insulin sensitivity research (preclinical)", "nad+ / methylation pathway discussion", "obesity research tools" ], "feel_search": [ "fat loss", "metabolic health", "body recomposition", "insulin sensitivity research (preclinical)", "nad+ / methylation pathway discussion", "obesity research tools" ], "summary": "NNMT inhibitors are a research class beyond 5-Amino-1MQ, studied for metabolic effects; different molecules are not interchangeable.", "search_blob": "nnmt inhibitor class (beyond 5-amino-1mq) 5-amino-1mq-analogs nnmt inhibitors 1mq analogs 5-amino-1mq analogs nnmti class jbsnf-000088 6-methoxynicotinamide jbsnf-000028 jbsnf-000265 mq-scaffold nnmt inhibitors 7-amino-1mq 2,3-diamino-1mq 1-methylquinolinium analogs nicotinamide n-methyltransferase inhibitors nam-competitive nnmt inhibitors tricyclic nnmt inhibitors (sanofi series) 5-amino-1mq-analogs 5 amino 1mq analogs 5amino1mqanalogs nnmt inhibitor class (beyond 5-amino-1mq) nnmt-inhibitor-class-(beyond-5-amino-1mq) nnmt inhibitors fat loss metabolic health body recomposition insulin sensitivity research (preclinical) nad+ / methylation pathway discussion obesity research tools fat loss metabolic health body recomposition insulin sensitivity research (preclinical) nad+ / methylation pathway discussion obesity research tools visceral adipose / white-fat nnmt narratives glp-1 stack adjunct (community, mostly via parent compound) next-gen / alternate nnmti curiosity after 5-amino-1mq hype muscle function / aged-muscle talk (parent scaffold; preclinical) diet-switch synergy narratives (preclinical nnmti class) fat loss metabolic health body recomposition insulin sensitivity research (preclinical) nad+ / methylation pathway discussion obesity research tools nnmt inhibitors are a research class beyond 5-amino-1mq, studied for metabolic effects; different molecules are not interchangeable. the available user log concerns parent 5-amino-1mq. it does not establish the feel, onset or duration of the other nnmt inhibitors. nnmt inhibitor class (beyond 5-amino-1mq) is an oral compound people look up for fat loss. insulin sensitization / glucose modulation reported. metabolic research compounds non-peptide systemic systemic \u2014 whole-body nnmt block aimed at adipose/liver nad salvage and sam/1-mna flux; oral small molecules dominate both papers and community talk. systemic whole-body circulating", "legal_class": null }, { "id": 124, "slug": "slu-pp-class", "name": "ERR agonist class (SLU-PP family)", "aliases": [ "ERR agonists", "exercise mimetic discussion class", "SLU-PP-332", "SLU-PP-915", "SLU-PP class", "SLU PP class", "ERR pan-agonists", "pan-ERR agonists", "Saint Louis University PP series", "Burris lab ERR agonists" ], "type": "Non-peptide", "category": "Metabolic research compounds", "goals_use_cases": [ "endurance", "fat loss", "metabolic health", "endurance / aerobic capacity (preclinical + community)", "fat loss / body recomposition (discussed)", "metabolic health / energy expenditure", "mitochondrial / oxidative capacity (discussed)", "insulin sensitivity / glucose markers (preclinical)", "exercise-mimetic research framing", "performance continuity without more volume (discussed)", "oral vs injectable metabolic research-chem culture", "heart-failure / cardiac metabolic research (preclinical, disease models)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "slu-pp-class", "slu pp class", "sluppclass", "ERR agonist class (SLU-PP family)", "err-agonist-class-(slu-pp-family)", "SLU-PP-332", "endurance / aerobic capacity (preclinical + community)", "fat loss / body recomposition (discussed)", "metabolic health / energy expenditure", "mitochondrial / oxidative capacity (discussed)", "insulin sensitivity / glucose markers (preclinical)", "exercise-mimetic research framing" ], "feel_search": [ "endurance / aerobic capacity (preclinical + community)", "fat loss / body recomposition (discussed)", "metabolic health / energy expenditure", "mitochondrial / oxidative capacity (discussed)", "insulin sensitivity / glucose markers (preclinical)", "exercise-mimetic research framing" ], "summary": "The SLU-PP family contains experimental small-molecule estrogen-related-receptor agonists, discussed for metabolism and endurance.", "search_blob": "err agonist class (slu-pp family) slu-pp-class err agonists exercise mimetic discussion class slu-pp-332 slu-pp-915 slu-pp class slu pp class err pan-agonists pan-err agonists saint louis university pp series burris lab err agonists slu-pp-class slu pp class sluppclass err agonist class (slu-pp family) err-agonist-class-(slu-pp-family) slu-pp-332 endurance / aerobic capacity (preclinical + community) fat loss / body recomposition (discussed) metabolic health / energy expenditure mitochondrial / oxidative capacity (discussed) insulin sensitivity / glucose markers (preclinical) exercise-mimetic research framing endurance fat loss metabolic health endurance / aerobic capacity (preclinical + community) fat loss / body recomposition (discussed) metabolic health / energy expenditure mitochondrial / oxidative capacity (discussed) insulin sensitivity / glucose markers (preclinical) exercise-mimetic research framing performance continuity without more volume (discussed) oral vs injectable metabolic research-chem culture heart-failure / cardiac metabolic research (preclinical, disease models) endurance / aerobic capacity (preclinical + community) fat loss / body recomposition (discussed) metabolic health / energy expenditure mitochondrial / oxidative capacity (discussed) insulin sensitivity / glucose markers (preclinical) exercise-mimetic research framing the slu-pp family contains experimental small-molecule estrogen-related-receptor agonists, discussed for metabolism and endurance. slu-pp-915 posters describe better endurance alongside fatigue or slower recovery; those reports cannot describe every slu-pp compound. err agonist class (slu-pp family) is an oral compound people look up for endurance. usual community checkpoint for \u201ccardio easier,\u201d sweat pattern, or scale/photos. metabolic research compounds non-peptide systemic systemic \u2014 small-molecule pan-err agonists studied for body-wide aerobic gene programs, energy use and exercise adaptation. systemic whole-body circulating", "legal_class": null }, { "id": 125, "slug": "ss-20", "name": "SS-20", "aliases": [ "Szeto-Schiller peptides adjacency", "SBT-20", "SBT-020", "SBT20", "SBT 20", "Phe-D-Arg-Phe-Lys-NH2", "H-Phe-D-Arg-Phe-Lys-NH2", "Szeto-Schiller peptide SS-20", "Szeto-Schiller peptide 20", "SS20", "SS 20" ], "type": "Peptide", "category": "Mitochondrial & metabolic peptides", "goals_use_cases": [ "aging", "mitochondrial discussion", "longevity", "mitochondrial discussion (class / analog to SS-31)", "longevity / bioenergetics interest (minority, mostly by adjacency)", "cellular energy / ATP support (discussed, preclinical-heavy)", "neuroprotection research (MPTP / dopaminergic models)", "oxidative stress and mtROS reduction (model-dependent)", "ischemia-reperfusion / cardioprotection research", "chronic kidney / renal mitochondrial research", "Huntington\u2019s disease investigational program (SBT-020)", "performance continuity (weak minority talk, usually SS-31 bleed)", "cardiolipin / IMM structure talk without Dmt scavenging" ], "delivery_methods": [ "research injection discussion" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "ss-20", "ss 20", "ss20", "SBT-20", "SBT-020", "SBT20", "mitochondrial discussion (class / analog to ss-31)", "longevity / bioenergetics interest (minority, mostly by adjacency)", "cellular energy / atp support (discussed, preclinical-heavy)", "neuroprotection research (mptp / dopaminergic models)", "oxidative stress and mtros reduction (model-dependent)", "ischemia-reperfusion / cardioprotection research" ], "feel_search": [ "mitochondrial discussion (class / analog to ss-31)", "longevity / bioenergetics interest (minority, mostly by adjacency)", "cellular energy / atp support (discussed, preclinical-heavy)", "neuroprotection research (mptp / dopaminergic models)", "oxidative stress and mtros reduction (model-dependent)", "ischemia-reperfusion / cardioprotection research" ], "summary": "SS-20 is a synthetic four-amino-acid Szeto\u2013Schiller peptide studied for mitochondrial biology; it is distinct from SS-31.", "search_blob": "ss-20 ss-20 szeto-schiller peptides adjacency sbt-20 sbt-020 sbt20 sbt 20 phe-d-arg-phe-lys-nh2 h-phe-d-arg-phe-lys-nh2 szeto-schiller peptide ss-20 szeto-schiller peptide 20 ss20 ss 20 ss-20 ss 20 ss20 sbt-20 sbt-020 sbt20 mitochondrial discussion (class / analog to ss-31) longevity / bioenergetics interest (minority, mostly by adjacency) cellular energy / atp support (discussed, preclinical-heavy) neuroprotection research (mptp / dopaminergic models) oxidative stress and mtros reduction (model-dependent) ischemia-reperfusion / cardioprotection research aging mitochondrial discussion longevity mitochondrial discussion (class / analog to ss-31) longevity / bioenergetics interest (minority, mostly by adjacency) cellular energy / atp support (discussed, preclinical-heavy) neuroprotection research (mptp / dopaminergic models) oxidative stress and mtros reduction (model-dependent) ischemia-reperfusion / cardioprotection research chronic kidney / renal mitochondrial research huntington\u2019s disease investigational program (sbt-020) performance continuity (weak minority talk, usually ss-31 bleed) cardiolipin / imm structure talk without dmt scavenging mitochondrial discussion (class / analog to ss-31) longevity / bioenergetics interest (minority, mostly by adjacency) cellular energy / atp support (discussed, preclinical-heavy) neuroprotection research (mptp / dopaminergic models) oxidative stress and mtros reduction (model-dependent) ischemia-reperfusion / cardioprotection research ss-20 is a synthetic four-amino-acid szeto\u2013schiller peptide studied for mitochondrial biology; it is distinct from ss-31. the inspected forum discusses related ss peptides and laboratory claims, rather than a direct ss-20 user experience. ss-20 is a peptide people look up for aging. no well-indexed week-by-week ss-20 self-experiment set comparable to ss-31, mots-c, or gh secretagogues. not ss-31/elamipretide/forzinity, not mots-c/humanin (mitochondrial-derived peptides), not an approved longevity or consumer drug, not a stimulant. mitochondrial & metabolic peptides peptide systemic systemic with preferential concentration at the inner mitochondrial membrane after parenteral exposure; far less community volume than ss-31/elamipretide. systemic whole-body circulating", "legal_class": null }, { "id": 126, "slug": "humanin-analogs", "name": "Humanin analogs (HNG etc.)", "aliases": [ "HNG", "S14G-humanin", "S14G-HN", "Humanin-G", "HN-S14G", "sHNG", "HNGF6A", "HNG-F6A", "colivelin", "AGA-(C8R)HNG17", "HN analogs", "synthetic humanin derivatives", "humanin analogues", "MAPRGFSCLLLLTGEIDLPVKRRA (HNG sequence)" ], "type": "Peptide", "category": "Mitochondrial & metabolic peptides", "goals_use_cases": [ "longevity", "neuroprotection discussion", "longevity / healthspan", "cognitive aging / AD research interest", "mitochondrial function / cytoprotection", "metabolic health", "insulin sensitivity (discussed)", "cardiovascular / ischemia research interest", "beta-cell survival / diabetes models", "healthy aging / healthspan", "anti-apoptotic cell-stress resilience", "chemotherapy-toxicity protection research (preclinical)", "stroke / MCAO model interest (preclinical)", "male germ-cell protection models (preclinical)" ], "delivery_methods": [ "research routes" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "humanin-analogs", "humanin analogs", "humaninanalogs", "Humanin analogs (HNG etc.)", "humanin-analogs-(hng-etc.)", "HNG", "longevity / healthspan", "neuroprotection discussion", "cognitive aging / ad research interest", "mitochondrial function / cytoprotection", "metabolic health", "insulin sensitivity (discussed)" ], "feel_search": [ "longevity / healthspan", "neuroprotection discussion", "cognitive aging / ad research interest", "mitochondrial function / cytoprotection", "metabolic health", "insulin sensitivity (discussed)" ], "summary": "Humanin analogs are modified versions such as HNG/S14G-humanin, studied mainly in cells and animals for stress protection and aging-related biology.", "search_blob": "humanin analogs (hng etc.) humanin-analogs hng s14g-humanin s14g-hn humanin-g hn-s14g shng hngf6a hng-f6a colivelin aga-(c8r)hng17 hn analogs synthetic humanin derivatives humanin analogues maprgfsclllltgeidlpvkrra (hng sequence) humanin-analogs humanin analogs humaninanalogs humanin analogs (hng etc.) humanin-analogs-(hng-etc.) hng longevity / healthspan neuroprotection discussion cognitive aging / ad research interest mitochondrial function / cytoprotection metabolic health insulin sensitivity (discussed) longevity neuroprotection discussion longevity / healthspan cognitive aging / ad research interest mitochondrial function / cytoprotection metabolic health insulin sensitivity (discussed) cardiovascular / ischemia research interest beta-cell survival / diabetes models healthy aging / healthspan anti-apoptotic cell-stress resilience chemotherapy-toxicity protection research (preclinical) stroke / mcao model interest (preclinical) male germ-cell protection models (preclinical) longevity / healthspan neuroprotection discussion cognitive aging / ad research interest mitochondrial function / cytoprotection metabolic health insulin sensitivity (discussed) humanin analogs are modified versions such as hng/s14g-humanin, studied mainly in cells and animals for stress protection and aging-related biology. humanin analogs (hng etc.) is a peptide people look up for longevity. clarity, sleep, energy, or resilience cannot be isolated to a humanin analog from these accounts. mitochondrial & metabolic peptides peptide systemic systemic \u2014 circulating cytoprotective/metabolic mdp-family signal with multi-organ research interest (brain, heart, islets, endothelium, testes, retina). systemic whole-body circulating", "legal_class": null }, { "id": 127, "slug": "shlp-class", "name": "SHLPs (small humanin-like peptides)", "aliases": [ "SHLP2", "SHLP6", "mitochondrial-derived peptides", "SHLP1\u20136", "SHLP1", "SHLP3", "SHLP4", "SHLP5", "small humanin-like peptides", "small humanin-like peptide 2", "mitochondrial-derived peptides SHLP", "MT-RNR2 SHLPs", "16S rRNA SHLPs", "K4R-SHLP2", "K4R SHLP2", "m.2158T>C SHLP2 variant" ], "type": "Peptide", "category": "Mitochondrial & metabolic peptides", "goals_use_cases": [ "longevity", "metabolic health", "longevity / healthspan discussion", "metabolic health / insulin sensitivity research", "mitochondrial function / OCR\u2013ATP modulation", "neuroprotection discussion (SHLP2)", "cytoprotection research (SHLP2/3)", "Parkinson\u2019s disease research interest (SHLP2 / K4R)", "age-related macular degeneration (AMD) cell models (SHLP2)", "islet amyloid / T2D mechanism research (SHLP2 + HNG)", "obesity / energy homeostasis models (SHLP2)", "apoptosis / oncology research interest (SHLP6)", "healthy aging / circulating-MDP decline narrative", "MDP multi-agent stack footnotes (humanin + MOTS-c + SHLP2)" ], "delivery_methods": [ "research" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "shlp-class", "shlp class", "shlpclass", "SHLPs (small humanin-like peptides)", "shlps-(small-humanin-like-peptides)", "SHLP1\u20136", "longevity / healthspan discussion", "metabolic health / insulin sensitivity research", "mitochondrial function / ocr\u2013atp modulation", "neuroprotection discussion (shlp2)", "cytoprotection research (shlp2/3)", "parkinson\u2019s disease research interest (shlp2 / k4r)" ], "feel_search": [ "longevity / healthspan discussion", "metabolic health / insulin sensitivity research", "mitochondrial function / ocr\u2013atp modulation", "neuroprotection discussion (shlp2)", "cytoprotection research (shlp2/3)", "parkinson\u2019s disease research interest (shlp2 / k4r)" ], "summary": "SHLP1\u20136 are small humanin-like peptides encoded in mitochondrial DNA, studied for cellular stress, metabolism and aging-related biology.", "search_blob": "shlps (small humanin-like peptides) shlp-class shlp2 shlp6 mitochondrial-derived peptides shlp1\u20136 shlp1 shlp3 shlp4 shlp5 small humanin-like peptides small humanin-like peptide 2 mitochondrial-derived peptides shlp mt-rnr2 shlps 16s rrna shlps k4r-shlp2 k4r shlp2 m.2158t>c shlp2 variant shlp-class shlp class shlpclass shlps (small humanin-like peptides) shlps-(small-humanin-like-peptides) shlp1\u20136 longevity / healthspan discussion metabolic health / insulin sensitivity research mitochondrial function / ocr\u2013atp modulation neuroprotection discussion (shlp2) cytoprotection research (shlp2/3) parkinson\u2019s disease research interest (shlp2 / k4r) longevity metabolic health longevity / healthspan discussion metabolic health / insulin sensitivity research mitochondrial function / ocr\u2013atp modulation neuroprotection discussion (shlp2) cytoprotection research (shlp2/3) parkinson\u2019s disease research interest (shlp2 / k4r) age-related macular degeneration (amd) cell models (shlp2) islet amyloid / t2d mechanism research (shlp2 + hng) obesity / energy homeostasis models (shlp2) apoptosis / oncology research interest (shlp6) healthy aging / circulating-mdp decline narrative mdp multi-agent stack footnotes (humanin + mots-c + shlp2) longevity / healthspan discussion metabolic health / insulin sensitivity research mitochondrial function / ocr\u2013atp modulation neuroprotection discussion (shlp2) cytoprotection research (shlp2/3) parkinson\u2019s disease research interest (shlp2 / k4r) shlp1\u20136 are small humanin-like peptides encoded in mitochondrial dna, studied for cellular stress, metabolism and aging-related biology. shlps (small humanin-like peptides) is a peptide people look up for longevity. more \u201ci\u2019m running the mdp suite\u201d habit than shlp-specific outcome series. mitochondrial & metabolic peptides peptide systemic systemic class \u2014 circulating mitochondrial-derived signals encoded in mtdna 16s rrna (mt-rnr2), same genomic neighborhood as humanin. systemic whole-body circulating", "legal_class": null }, { "id": 128, "slug": "apigenin", "name": "Apigenin", "aliases": [ "CD38 discussion flavonoid", "4',5,7-trihydroxyflavone", "Apigenin flavonoid", "Chamomile flavonoid (dietary context)", "5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one", "Huberman sleep-stack apigenin (community shorthand)", "Apigenine (common misspelling/EU labeling)", "C15H10O5 flavone" ], "type": "Non-peptide", "category": "Longevity & cellular energy", "goals_use_cases": [ "longevity", "sleep adjacency", "NAD discussion", "CD38 / NAD salvage interest", "anxiety / calm (discussed)", "inflammation (discussed)", "antioxidant / polyphenol stack interest", "healthy aging / healthspan", "senomorphic / SASP quieting interest (preclinical talk)", "GABA-A / wind-down support (community)", "NMN/NR stack companion", "Huberman-style nightly sleep cocktail", "mood / GAD-adjacent chamomile pathway (extract literature)", "metabolic / glucose-lipid animal-model interest", "muscle / physical-capacity adjacency (mouse N+A and standalone lore)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "apigenin", "4',5,7-trihydroxyflavone", "CD38 discussion flavonoid", "Apigenin flavonoid", "Chamomile flavonoid (dietary context)", "5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one", "longevity", "sleep adjacency", "nad discussion", "cd38 / nad salvage interest", "anxiety / calm (discussed)", "inflammation (discussed)" ], "feel_search": [ "longevity", "sleep adjacency", "nad discussion", "cd38 / nad salvage interest", "anxiety / calm (discussed)", "inflammation (discussed)" ], "summary": "Apigenin is a plant flavone found in chamomile and other foods, sold as a supplement for sleep and relaxation.", "search_blob": "apigenin apigenin cd38 discussion flavonoid 4',5,7-trihydroxyflavone apigenin flavonoid chamomile flavonoid (dietary context) 5,7-dihydroxy-2-(4-hydroxyphenyl)-4h-1-benzopyran-4-one huberman sleep-stack apigenin (community shorthand) apigenine (common misspelling/eu labeling) c15h10o5 flavone apigenin 4',5,7-trihydroxyflavone cd38 discussion flavonoid apigenin flavonoid chamomile flavonoid (dietary context) 5,7-dihydroxy-2-(4-hydroxyphenyl)-4h-1-benzopyran-4-one longevity sleep adjacency nad discussion cd38 / nad salvage interest anxiety / calm (discussed) inflammation (discussed) longevity sleep adjacency nad discussion cd38 / nad salvage interest anxiety / calm (discussed) inflammation (discussed) antioxidant / polyphenol stack interest healthy aging / healthspan senomorphic / sasp quieting interest (preclinical talk) gaba-a / wind-down support (community) nmn/nr stack companion huberman-style nightly sleep cocktail mood / gad-adjacent chamomile pathway (extract literature) metabolic / glucose-lipid animal-model interest muscle / physical-capacity adjacency (mouse n+a and standalone lore) longevity sleep adjacency nad discussion cd38 / nad salvage interest anxiety / calm (discussed) inflammation (discussed) apigenin is a plant flavone found in chamomile and other foods, sold as a supplement for sleep and relaxation. one commenter reports calmer mood; another sleeps more continuously with magnesium co-use. others report little effect, brief benefit that fades, irritability, night waking or next-day fog. apigenin is an oral compound people look up for sleep. users report easier evening downshift on capsules; often confounded by mag/theanine/chamomile ritual in the same stack. longevity & cellular energy non-peptide systemic systemic \u2014 oral plant flavone discussed in calm, sleep and nad/cd38 stacks; not a local injectate or topical research peptide. systemic whole-body circulating", "legal_class": null }, { "id": 129, "slug": "pqq", "name": "PQQ", "aliases": [ "Pyrroloquinoline quinone", "PQQ disodium salt", "Pyrroloquinoline quinone disodium", "PQQ\u00b7Na2", "Methoxatin (chemical synonym in literature)", "BioPQQ (Mitsubishi branded fermented form)", "mnemoPQQ (Ryusendo branded form in some Japanese trials)", "PureQQ (Nascent chemically synthesized form)", "MGCPQQ (EU novel-food branded form discussed)" ], "type": "Non-peptide", "category": "Longevity & cellular energy", "goals_use_cases": [ "mitochondrial discussion", "cognition", "energy", "mitochondrial discussion / biogenesis talk", "cognition / memory / attention (healthy adults)", "energy / subjective fatigue reduction", "longevity / healthy-aging stacks", "sleep quality (open-label discussion)", "mood / stress (discussed)", "antioxidant / redox-cycling discussion", "inflammation markers (CRP/IL-6 talk)", "LDL / lipid discussion (small trial)", "exercise + mito-marker stacks (not clear ergogen)", "performance support (discussed; weak single-agent proof)", "CoQ10 companion in mitochondrial formulas" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "pqq", "Pyrroloquinoline quinone", "PQQ disodium salt", "Pyrroloquinoline quinone disodium", "PQQ\u00b7Na2", "Methoxatin (chemical synonym in literature)", "mitochondrial discussion / biogenesis talk", "cognition / memory / attention (healthy adults)", "energy / subjective fatigue reduction", "longevity / healthy-aging stacks", "sleep quality (open-label discussion)", "mood / stress (discussed)" ], "feel_search": [ "mitochondrial discussion / biogenesis talk", "cognition / memory / attention (healthy adults)", "energy / subjective fatigue reduction", "longevity / healthy-aging stacks", "sleep quality (open-label discussion)", "mood / stress (discussed)" ], "summary": "PQQ is a redox-active small molecule, commonly sold as an oral disodium-salt supplement for mitochondrial and energy-related interests.", "search_blob": "pqq pqq pyrroloquinoline quinone pqq disodium salt pyrroloquinoline quinone disodium pqq\u00b7na2 methoxatin (chemical synonym in literature) biopqq (mitsubishi branded fermented form) mnemopqq (ryusendo branded form in some japanese trials) pureqq (nascent chemically synthesized form) mgcpqq (eu novel-food branded form discussed) pqq pyrroloquinoline quinone pqq disodium salt pyrroloquinoline quinone disodium pqq\u00b7na2 methoxatin (chemical synonym in literature) mitochondrial discussion / biogenesis talk cognition / memory / attention (healthy adults) energy / subjective fatigue reduction longevity / healthy-aging stacks sleep quality (open-label discussion) mood / stress (discussed) mitochondrial discussion cognition energy mitochondrial discussion / biogenesis talk cognition / memory / attention (healthy adults) energy / subjective fatigue reduction longevity / healthy-aging stacks sleep quality (open-label discussion) mood / stress (discussed) antioxidant / redox-cycling discussion inflammation markers (crp/il-6 talk) ldl / lipid discussion (small trial) exercise + mito-marker stacks (not clear ergogen) performance support (discussed; weak single-agent proof) coq10 companion in mitochondrial formulas mitochondrial discussion / biogenesis talk cognition / memory / attention (healthy adults) energy / subjective fatigue reduction longevity / healthy-aging stacks sleep quality (open-label discussion) mood / stress (discussed) pqq is a redox-active small molecule, commonly sold as an oral disodium-salt supplement for mitochondrial and energy-related interests. the thread includes feeling warmer, no change after 90 days, and different responses in people reporting mitochondrial problems. pqq is an oral supplement people look up for energy. modest gains in memory, attention, processing/executive speed domains in some trials. longevity & cellular energy non-peptide systemic systemic \u2014 oral water-soluble redox quinone framed for body-wide cellular energy and mitochondrial signaling, not local injectable repair or a stimulant. systemic whole-body circulating", "legal_class": null }, { "id": 130, "slug": "coq10", "name": "CoQ10 / Ubiquinol", "aliases": [ "ubiquinone", "ubiquinol", "Coenzyme Q10", "ubidecarenone", "CoQ-10", "coenzyme Q-10", "CoQH2 / CoQ10H2 (reduced form nomenclature)", "Kaneka Ubiquinol (branded reduced form often cited)", "Bio-Quinone / Myoqinon (trial/soft-gel ubiquinone brands discussed)" ], "type": "Non-peptide", "category": "Longevity & cellular energy", "goals_use_cases": [ "mitochondrial discussion", "cardiovascular discussion", "energy", "cardiovascular / heart-failure adjunct discussion", "energy / fatigue (subjective)", "longevity / healthy aging", "statin-related muscle comfort (discussed; evidence mixed)", "antioxidant / membrane redox support (discussed)", "blood-pressure support (discussed)", "migraine prevention (nutraceutical stack talk)", "male fertility / sperm quality narratives", "exercise recovery / \u201cmito stack\u201d performance talk", "neurodegeneration high-dose research lore (Parkinson/Huntington trial culture)", "comparison of ubiquinone vs ubiquinol forms" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "coq10", "CoQ10 / Ubiquinol", "coq10-/-ubiquinol", "Coenzyme Q10", "ubiquinone", "ubiquinol", "mitochondrial discussion", "cardiovascular / heart-failure adjunct discussion", "energy / fatigue (subjective)", "longevity / healthy aging", "statin-related muscle comfort (discussed; evidence mixed)", "antioxidant / membrane redox support (discussed)" ], "feel_search": [ "mitochondrial discussion", "cardiovascular / heart-failure adjunct discussion", "energy / fatigue (subjective)", "longevity / healthy aging", "statin-related muscle comfort (discussed; evidence mixed)", "antioxidant / membrane redox support (discussed)" ], "summary": "CoQ10 is a normal cell-energy cofactor sold as ubiquinone or ubiquinol supplements, discussed for energy, migraine and cardiovascular interests.", "search_blob": "coq10 / ubiquinol coq10 ubiquinone ubiquinol coenzyme q10 ubidecarenone coq-10 coenzyme q-10 coqh2 / coq10h2 (reduced form nomenclature) kaneka ubiquinol (branded reduced form often cited) bio-quinone / myoqinon (trial/soft-gel ubiquinone brands discussed) coq10 coq10 / ubiquinol coq10-/-ubiquinol coenzyme q10 ubiquinone ubiquinol mitochondrial discussion cardiovascular / heart-failure adjunct discussion energy / fatigue (subjective) longevity / healthy aging statin-related muscle comfort (discussed; evidence mixed) antioxidant / membrane redox support (discussed) mitochondrial discussion cardiovascular discussion energy cardiovascular / heart-failure adjunct discussion energy / fatigue (subjective) longevity / healthy aging statin-related muscle comfort (discussed; evidence mixed) antioxidant / membrane redox support (discussed) blood-pressure support (discussed) migraine prevention (nutraceutical stack talk) male fertility / sperm quality narratives exercise recovery / \u201cmito stack\u201d performance talk neurodegeneration high-dose research lore (parkinson/huntington trial culture) comparison of ubiquinone vs ubiquinol forms mitochondrial discussion cardiovascular / heart-failure adjunct discussion energy / fatigue (subjective) longevity / healthy aging statin-related muscle comfort (discussed; evidence mixed) antioxidant / membrane redox support (discussed) coq10 is a normal cell-energy cofactor sold as ubiquinone or ubiquinol supplements, discussed for energy, migraine and cardiovascular interests. sleep reports point in opposite directions: one ubiquinol user sleeps better without extra daytime energy; another coq10 user feels energized but develops worse insomnia. coq10 / ubiquinol is an oral compound for energy. recovery and \u201cmito stack\u201d anecdotes common; single-agent performance proof weaker than multi-nutrient or training-block confounds. longevity & cellular energy non-peptide systemic systemic oral fat-soluble cofactor aimed at circulating and tissue coq pools; not a local injectable peptide or acute stimulant. systemic whole-body circulating", "legal_class": null }, { "id": 131, "slug": "alpha-lipoic-acid", "name": "Alpha-Lipoic Acid (ALA)", "aliases": [ "R-ALA", "thioctic acid", "ALA", "\u03b1-Lipoic acid", "alpha lipoic acid", "Thioctic acid", "R-lipoic acid", "R-(+)-lipoic acid", "S-lipoic acid", "R,S-lipoic acid (racemic)", "d,l-lipoic acid", "Na-RALA (sodium R-lipoate)", "sodium R-lipoate", "Dihydrolipoic acid (DHLA / reduced form)", "thioctic acid (EU/clinical synonym)" ], "type": "Non-peptide", "category": "Antioxidant & metabolic adjacents", "goals_use_cases": [ "metabolic health", "neuropathy discussion", "antioxidant discussion", "diabetic peripheral neuropathy symptom discussion", "burning / tingling / paresthesia threads (diabetic and idiopathic)", "metabolic health / insulin sensitivity talk", "glucose / HbA1c adjacency", "antioxidant / redox / oxidative-stress stacks", "mitochondrial cofactor / mito-support framing", "bodybuilding nutrient-partitioning / carb-meal timing (R-ALA / Na-RALA lore)", "weight management adjacency (modest meta signals)", "ALCAR + ALA neuropathy / mito duo", "liver / detox / heavy-metal chelation narratives (mostly preclinical/community)", "skin / cosmeceutical antioxidant adjacency (minority)", "cardiac autonomic neuropathy (CAN) discussion (narrow trial talk)", "MS / neuroinflammation research adjacency (high-dose oral pilots)", "chemotherapy-induced neuropathy adjacency (mixed/debated)" ], "delivery_methods": [ "oral", "IV" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "alpha-lipoic-acid", "alpha lipoic acid", "alphalipoicacid", "Alpha-Lipoic Acid (ALA)", "alpha-lipoic-acid-(ala)", "ALA", "diabetic peripheral neuropathy symptom discussion", "burning / tingling / paresthesia threads (diabetic and idiopathic)", "metabolic health / insulin sensitivity talk", "glucose / hba1c adjacency", "antioxidant / redox / oxidative-stress stacks", "mitochondrial cofactor / mito-support framing" ], "feel_search": [ "diabetic peripheral neuropathy symptom discussion", "burning / tingling / paresthesia threads (diabetic and idiopathic)", "metabolic health / insulin sensitivity talk", "glucose / hba1c adjacency", "antioxidant / redox / oxidative-stress stacks", "mitochondrial cofactor / mito-support framing" ], "summary": "ALA is a non-peptide supplement discussed for burning or tingling nerve symptoms, metabolic health and antioxidant stacks. Threads report less burning after weeks.", "search_blob": "alpha-lipoic acid (ala) alpha-lipoic-acid r-ala thioctic acid ala \u03b1-lipoic acid alpha lipoic acid thioctic acid r-lipoic acid r-(+)-lipoic acid s-lipoic acid r,s-lipoic acid (racemic) d,l-lipoic acid na-rala (sodium r-lipoate) sodium r-lipoate dihydrolipoic acid (dhla / reduced form) thioctic acid (eu/clinical synonym) alpha-lipoic-acid alpha lipoic acid alphalipoicacid alpha-lipoic acid (ala) alpha-lipoic-acid-(ala) ala diabetic peripheral neuropathy symptom discussion burning / tingling / paresthesia threads (diabetic and idiopathic) metabolic health / insulin sensitivity talk glucose / hba1c adjacency antioxidant / redox / oxidative-stress stacks mitochondrial cofactor / mito-support framing metabolic health neuropathy discussion antioxidant discussion diabetic peripheral neuropathy symptom discussion burning / tingling / paresthesia threads (diabetic and idiopathic) metabolic health / insulin sensitivity talk glucose / hba1c adjacency antioxidant / redox / oxidative-stress stacks mitochondrial cofactor / mito-support framing bodybuilding nutrient-partitioning / carb-meal timing (r-ala / na-rala lore) weight management adjacency (modest meta signals) alcar + ala neuropathy / mito duo liver / detox / heavy-metal chelation narratives (mostly preclinical/community) skin / cosmeceutical antioxidant adjacency (minority) cardiac autonomic neuropathy (can) discussion (narrow trial talk) ms / neuroinflammation research adjacency (high-dose oral pilots) chemotherapy-induced neuropathy adjacency (mixed/debated) diabetic peripheral neuropathy symptom discussion burning / tingling / paresthesia threads (diabetic and idiopathic) metabolic health / insulin sensitivity talk glucose / hba1c adjacency antioxidant / redox / oxidative-stress stacks mitochondrial cofactor / mito-support framing ala is a non-peptide supplement discussed for burning or tingling nerve symptoms, metabolic health and antioxidant stacks. threads report less burning after weeks. neuropathy reports range from relief within hours to a subtle change noticed only after stopping. several accounts combine ala with benfotiamine, obscuring attribution. ala is a non-peptide supplement discussed for burning or tingling nerve symptoms, metabolic health and antioxidant stacks. threads report less burning after weeks. antioxidant & metabolic adjacents non-peptide systemic systemic \u2014 oral (consumer/research) and clinical iv antioxidant and mitochondrial cofactor with whole-body metabolic and neuropathy talk. systemic whole-body circulating", "legal_class": null }, { "id": 132, "slug": "taurine", "name": "Taurine", "aliases": [ "L-taurine", "2-aminoethanesulfonic acid", "tauric acid (historical name in some older texts)", "2-aminoethane-1-sulfonic acid", "Tau (abbreviation in papers)" ], "type": "Non-peptide", "category": "Longevity & performance staples", "goals_use_cases": [ "longevity", "performance", "metabolic health", "longevity / healthspan (post-2023 animal papers)", "performance / exercise capacity", "pre-workout ergogenic interest", "metabolic health (glucose, lipids, inflammation markers)", "cardiovascular / blood-pressure discussion", "heart-failure research interest (clinical literature)", "recovery / DOMS talk", "muscle cramp stacks (with electrolytes)", "cellular stress / osmoregulation narratives", "sleep / calm (minority)", "vegan / low-meat dietary gap talk", "energy-drink ingredient literacy" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "taurine", "L-taurine", "2-aminoethanesulfonic acid", "tauric acid (historical name in some older texts)", "2-aminoethane-1-sulfonic acid", "Tau (abbreviation in papers)", "longevity / healthspan (post-2023 animal papers)", "performance / exercise capacity", "pre-workout ergogenic interest", "metabolic health (glucose, lipids, inflammation markers)", "cardiovascular / blood-pressure discussion", "heart-failure research interest (clinical literature)" ], "feel_search": [ "longevity / healthspan (post-2023 animal papers)", "performance / exercise capacity", "pre-workout ergogenic interest", "metabolic health (glucose, lipids, inflammation markers)", "cardiovascular / blood-pressure discussion", "heart-failure research interest (clinical literature)" ], "summary": "Taurine is a sulfur-containing amino sulfonic acid made by the body and found in animal foods, supplements and many energy drinks.", "search_blob": "taurine taurine l-taurine 2-aminoethanesulfonic acid tauric acid (historical name in some older texts) 2-aminoethane-1-sulfonic acid tau (abbreviation in papers) taurine l-taurine 2-aminoethanesulfonic acid tauric acid (historical name in some older texts) 2-aminoethane-1-sulfonic acid tau (abbreviation in papers) longevity / healthspan (post-2023 animal papers) performance / exercise capacity pre-workout ergogenic interest metabolic health (glucose, lipids, inflammation markers) cardiovascular / blood-pressure discussion heart-failure research interest (clinical literature) longevity performance metabolic health longevity / healthspan (post-2023 animal papers) performance / exercise capacity pre-workout ergogenic interest metabolic health (glucose, lipids, inflammation markers) cardiovascular / blood-pressure discussion heart-failure research interest (clinical literature) recovery / doms talk muscle cramp stacks (with electrolytes) cellular stress / osmoregulation narratives sleep / calm (minority) vegan / low-meat dietary gap talk energy-drink ingredient literacy longevity / healthspan (post-2023 animal papers) performance / exercise capacity pre-workout ergogenic interest metabolic health (glucose, lipids, inflammation markers) cardiovascular / blood-pressure discussion heart-failure research interest (clinical literature) taurine is a sulfur-containing amino sulfonic acid made by the body and found in animal foods, supplements and many energy drinks. accounts range from calm and less rumination to next-day drowsiness, headache or feeling wired and anxious. taurine is an oral compound people look up for longevity. some claim fewer cramps, better dense sessions, or slightly better endurance feel; others null. longevity & performance staples non-peptide systemic systemic \u2014 a free amino sulfonic acid discussed for muscle, heart, brain and bile-acid functions; not a site-specific injection. systemic whole-body circulating", "legal_class": null }, { "id": 133, "slug": "glycine", "name": "Glycine", "aliases": [ "glycinate adjacency", "collagen amino acid", "Gly", "L-glycine", "aminoacetic acid", "2-aminoacetic acid", "glycinate adjacency (Mg glycinate / bisglycinate salts \u2014 not gram-equivalent free glycine)", "GlyNAC (glycine + NAC stack name)", "free-form glycine powder", "glycine monohydrate (bulk powder form shorthand)" ], "type": "Non-peptide", "category": "Sleep & longevity staples", "goals_use_cases": [ "sleep", "longevity", "recovery", "sleep quality / onset / next-day refresh", "sleep restriction recovery / less daytime fatigue after short nights", "longevity / methionine-restriction-mimetic talk", "collagen / connective tissue support (discussed)", "joint, tendon, skin adjacency (discussed)", "glutathione / antioxidant support (GlyNAC and solo GSH-precursor talk)", "recovery / training-adjacent soft-tissue talk", "evening wind-down / mild calm (not knockout sedation)", "metabolic / insulin-sensitivity interest (mixed; population caveats)", "schizophrenia negative-symptom adjunct research context (high-dose clinical only)", "creatine / purine / one-carbon metabolism adjacency", "Huberman-adjacent intermittent sleep-stack add-on talk" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "glycine", "Gly", "L-glycine", "aminoacetic acid", "2-aminoacetic acid", "glycinate adjacency (Mg glycinate / bisglycinate salts \u2014 not gram-equivalent free glycine)", "sleep quality / onset / next-day refresh", "sleep restriction recovery / less daytime fatigue after short nights", "longevity / methionine-restriction-mimetic talk", "collagen / connective tissue support (discussed)", "joint, tendon, skin adjacency (discussed)", "glutathione / antioxidant support (glynac and solo gsh-precursor talk)" ], "feel_search": [ "sleep quality / onset / next-day refresh", "sleep restriction recovery / less daytime fatigue after short nights", "longevity / methionine-restriction-mimetic talk", "collagen / connective tissue support (discussed)", "joint, tendon, skin adjacency (discussed)", "glutathione / antioxidant support (glynac and solo gsh-precursor talk)" ], "summary": "Glycine is an amino acid taken as powder or capsules; biohackers mainly discuss sleep quality, next-day alertness and GlyNAC combinations.", "search_blob": "glycine glycine glycinate adjacency collagen amino acid gly l-glycine aminoacetic acid 2-aminoacetic acid glycinate adjacency (mg glycinate / bisglycinate salts \u2014 not gram-equivalent free glycine) glynac (glycine + nac stack name) free-form glycine powder glycine monohydrate (bulk powder form shorthand) glycine gly l-glycine aminoacetic acid 2-aminoacetic acid glycinate adjacency (mg glycinate / bisglycinate salts \u2014 not gram-equivalent free glycine) sleep quality / onset / next-day refresh sleep restriction recovery / less daytime fatigue after short nights longevity / methionine-restriction-mimetic talk collagen / connective tissue support (discussed) joint, tendon, skin adjacency (discussed) glutathione / antioxidant support (glynac and solo gsh-precursor talk) sleep longevity recovery sleep quality / onset / next-day refresh sleep restriction recovery / less daytime fatigue after short nights longevity / methionine-restriction-mimetic talk collagen / connective tissue support (discussed) joint, tendon, skin adjacency (discussed) glutathione / antioxidant support (glynac and solo gsh-precursor talk) recovery / training-adjacent soft-tissue talk evening wind-down / mild calm (not knockout sedation) metabolic / insulin-sensitivity interest (mixed; population caveats) schizophrenia negative-symptom adjunct research context (high-dose clinical only) creatine / purine / one-carbon metabolism adjacency huberman-adjacent intermittent sleep-stack add-on talk sleep quality / onset / next-day refresh sleep restriction recovery / less daytime fatigue after short nights longevity / methionine-restriction-mimetic talk collagen / connective tissue support (discussed) joint, tendon, skin adjacency (discussed) glutathione / antioxidant support (glynac and solo gsh-precursor talk) glycine is an amino acid taken as powder or capsules; biohackers mainly discuss sleep quality, next-day alertness and glynac combinations. glycine is an oral compound people look up for sleep. mild calm, easier onset, warmer hands/feet or \u201ccooler core\u201d lore \u2014 or nothing noticeable. sleep & longevity staples non-peptide systemic systemic \u2014 oral free amino acid; sleep thermoregulation, collagen substrate, and glutathione-precursor goals are framed whole-body, not site-injected. systemic whole-body circulating", "legal_class": null }, { "id": 134, "slug": "tongkat-ali", "name": "Tongkat Ali", "aliases": [ "Eurycoma longifolia", "LJ100", "Eurycoma longifolia Jack", "Physta", "Longjack", "Long Jack", "Pasak Bumi", "Malaysian ginseng (informal marketplace label)", "Tongkat", "TA (forum shorthand)" ], "type": "Non-peptide", "category": "Herbals in hormone discourse", "goals_use_cases": [ "libido", "hormone axis", "stress", "stress / cortisol balance (discussed)", "testosterone support (discussed)", "sexual function", "mood / vitality (discussed)", "male fertility / semen parameters (discussed)", "fatigue / AMS scores (discussed)", "performance continuity", "aging male wellness (discussed)", "free testosterone talk (community)", "women's libido/stress crossover (discussed)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "tongkat-ali", "tongkat ali", "tongkatali", "Eurycoma longifolia", "Eurycoma longifolia Jack", "LJ100", "libido", "hormone axis", "stress / cortisol balance (discussed)", "testosterone support (discussed)", "sexual function", "mood / vitality (discussed)" ], "feel_search": [ "libido", "hormone axis", "stress / cortisol balance (discussed)", "testosterone support (discussed)", "sexual function", "mood / vitality (discussed)" ], "summary": "Tongkat Ali is the root herb Eurycoma longifolia, commonly sold as standardized extracts for libido and hormone-related interests.", "search_blob": "tongkat ali tongkat-ali eurycoma longifolia lj100 eurycoma longifolia jack physta longjack long jack pasak bumi malaysian ginseng (informal marketplace label) tongkat ta (forum shorthand) tongkat-ali tongkat ali tongkatali eurycoma longifolia eurycoma longifolia jack lj100 libido hormone axis stress / cortisol balance (discussed) testosterone support (discussed) sexual function mood / vitality (discussed) libido hormone axis stress stress / cortisol balance (discussed) testosterone support (discussed) sexual function mood / vitality (discussed) male fertility / semen parameters (discussed) fatigue / ams scores (discussed) performance continuity aging male wellness (discussed) free testosterone talk (community) women's libido/stress crossover (discussed) libido hormone axis stress / cortisol balance (discussed) testosterone support (discussed) sexual function mood / vitality (discussed) tongkat ali is the root herb eurycoma longifolia, commonly sold as standardized extracts for libido and hormone-related interests. one long-term user described an energizing effect followed by marked brain fog; other supplements and wellbutrin complicated attribution. tongkat ali is an oral supplement people look up for libido. common first real check-in for libido, mood, training motivation; talbott stress study window is 4 weeks. herbals in hormone discourse non-peptide systemic systemic oral root extract\u2014hpg axis, stress-hormone, and whole-body vitality pathways, not a single local target. systemic whole-body circulating", "legal_class": null }, { "id": 135, "slug": "fadogia-agrestis", "name": "Fadogia agrestis", "aliases": [ "Fadogia", "Black aphrodisiac", "Baakin gagai", "Fadogia agrestis stem extract", "Fadogia agrestis (Schweinf. Ex Hiern)", "Fadogia agrestis (Rubiaceae)", "Nigerian fadogia (marketplace shorthand)", "FA (forum shorthand)", "Fadogia + Tongkat stack (combo product context)" ], "type": "Non-peptide", "category": "Herbals in hormone discourse", "goals_use_cases": [ "libido", "hormone axis", "sexual function (discussed)", "free testosterone (discussed)", "total testosterone (discussed)", "luteinizing hormone (LH) support (discussed)", "performance continuity", "male vitality (discussed)", "morning wood / drive (community)", "natural T stack companion to tongkat (discussed)", "athletic recovery / training mood (discussed)", "anti-TRT bridge or TRT-avoidance self-experiment (discussed)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "fadogia-agrestis", "fadogia agrestis", "fadogiaagrestis", "Fadogia", "Black aphrodisiac", "Baakin gagai", "libido", "hormone axis", "sexual function (discussed)", "free testosterone (discussed)", "total testosterone (discussed)", "luteinizing hormone (lh) support (discussed)" ], "feel_search": [ "libido", "hormone axis", "sexual function (discussed)", "free testosterone (discussed)", "total testosterone (discussed)", "luteinizing hormone (lh) support (discussed)" ], "summary": "Fadogia agrestis is a shrub sold as an oral plant extract for libido and testosterone-related interest; human evidence remains limited.", "search_blob": "fadogia agrestis fadogia-agrestis fadogia black aphrodisiac baakin gagai fadogia agrestis stem extract fadogia agrestis (schweinf. ex hiern) fadogia agrestis (rubiaceae) nigerian fadogia (marketplace shorthand) fa (forum shorthand) fadogia + tongkat stack (combo product context) fadogia-agrestis fadogia agrestis fadogiaagrestis fadogia black aphrodisiac baakin gagai libido hormone axis sexual function (discussed) free testosterone (discussed) total testosterone (discussed) luteinizing hormone (lh) support (discussed) libido hormone axis sexual function (discussed) free testosterone (discussed) total testosterone (discussed) luteinizing hormone (lh) support (discussed) performance continuity male vitality (discussed) morning wood / drive (community) natural t stack companion to tongkat (discussed) athletic recovery / training mood (discussed) anti-trt bridge or trt-avoidance self-experiment (discussed) libido hormone axis sexual function (discussed) free testosterone (discussed) total testosterone (discussed) luteinizing hormone (lh) support (discussed) fadogia agrestis is a shrub sold as an oral plant extract for libido and testosterone-related interest; human evidence remains limited. a six-week user reports better libido and erections without a testosterone rise on their bloodwork. testicular fullness in other posts is not proof of higher testosterone. fadogia is an oral extract for libido. some link \u201caggressive\u201d gym mood, recovery feel, or recomp drive; hard to isolate from caffeine, sleep, calorie deficit, or placebo. not trt, not a serm/ai, not enclomiphene, not hcg, not a sarm; extract ratio, plant part, solvent, and assay quality vary widely by brand. herbals in hormone discourse non-peptide systemic systemic oral plant extract discussed for libido and hormone effects; human efficacy, pharmacokinetics, and product equivalence are not established. systemic whole-body circulating", "legal_class": null }, { "id": 136, "slug": "boron", "name": "Boron", "aliases": [ "boron glycinate", "boron citrate", "boron aspartate", "boron gluconate", "boron amino acid chelate", "boron picolinate / ascorbate (less common labels)", "triple boron (citrate + aspartate + glycinate blends)", "tri-boron / Tri-Boron Plus (marketplace multi-salt brands)", "calcium fructoborate (CFB / plant-complex form; e.g. FruiteX-B marketing lineage)", "sodium borate / sodium tetraborate", "boric acid (research chemistry / some labels; also topical/vaginal niche)", "borax (household sodium tetraborate \u2014 not equivalent to measured supplement use)", "elemental boron (label math basis)" ], "type": "Non-peptide", "category": "Minerals in hormone discourse", "goals_use_cases": [ "libido", "hormone axis", "joints discussion", "free testosterone (discussed)", "SHBG modulation (discussed)", "estradiol balance talk (sex- and duration-dependent)", "joints / osteoarthritis discussion", "bone mineral support / osteopenia stacks (discussed)", "inflammation markers (hs-CRP, TNF-\u03b1, IL-6 discussed)", "vitamin D status / metabolite half-life talk", "magnesium absorption / urinary Mg conservation (discussed)", "urinary calcium conservation (discussed)", "performance continuity / multi-mineral stacks", "peri-postmenopause mineral talk (mixed symptom data)", "cognitive / alertness lore from depletion designs (secondary)", "wound-healing topical boric-acid niche (separate from oral free-T stacks)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "boron", "boron glycinate", "boron citrate", "boron aspartate", "boron gluconate", "boron amino acid chelate", "hormone axis", "free testosterone (discussed)", "shbg modulation (discussed)", "estradiol balance talk (sex- and duration-dependent)", "joints / osteoarthritis discussion", "bone mineral support / osteopenia stacks (discussed)" ], "feel_search": [ "hormone axis", "free testosterone (discussed)", "shbg modulation (discussed)", "estradiol balance talk (sex- and duration-dependent)", "joints / osteoarthritis discussion", "bone mineral support / osteopenia stacks (discussed)" ], "summary": "Boron is a dietary trace element sold in several supplement salts; biohackers discuss it for bone health and hormone-related symptoms.", "search_blob": "boron boron boron glycinate boron citrate boron aspartate boron gluconate boron amino acid chelate boron picolinate / ascorbate (less common labels) triple boron (citrate + aspartate + glycinate blends) tri-boron / tri-boron plus (marketplace multi-salt brands) calcium fructoborate (cfb / plant-complex form; e.g. fruitex-b marketing lineage) sodium borate / sodium tetraborate boric acid (research chemistry / some labels; also topical/vaginal niche) borax (household sodium tetraborate \u2014 not equivalent to measured supplement use) elemental boron (label math basis) boron boron glycinate boron citrate boron aspartate boron gluconate boron amino acid chelate hormone axis free testosterone (discussed) shbg modulation (discussed) estradiol balance talk (sex- and duration-dependent) joints / osteoarthritis discussion bone mineral support / osteopenia stacks (discussed) libido hormone axis joints discussion free testosterone (discussed) shbg modulation (discussed) estradiol balance talk (sex- and duration-dependent) joints / osteoarthritis discussion bone mineral support / osteopenia stacks (discussed) inflammation markers (hs-crp, tnf-\u03b1, il-6 discussed) vitamin d status / metabolite half-life talk magnesium absorption / urinary mg conservation (discussed) urinary calcium conservation (discussed) performance continuity / multi-mineral stacks peri-postmenopause mineral talk (mixed symptom data) cognitive / alertness lore from depletion designs (secondary) wound-healing topical boric-acid niche (separate from oral free-t stacks) hormone axis free testosterone (discussed) shbg modulation (discussed) estradiol balance talk (sex- and duration-dependent) joints / osteoarthritis discussion bone mineral support / osteopenia stacks (discussed) boron is a dietary trace element sold in several supplement salts; biohackers discuss it for bone health and hormone-related symptoms. one user reports lower libido during use and a rebound after stopping, while taking several other supplements. other comments report only a brief initial lift. boron is an oral dietary trace element people look up for joints. cfb knee pilots sometimes claim earlier womac movement by day 7\u201314. minerals in hormone discourse non-peptide systemic systemic oral trace mineral \u2014 whole-body hormone, bone, joint, vitamin d, magnesium/calcium conservation, and inflammatory-marker talk. systemic whole-body circulating", "legal_class": null }, { "id": 137, "slug": "clomiphene", "name": "Clomiphene", "aliases": [ "Clomid", "clomifene", "Clomiphene citrate", "Clomid (brand)", "Clomifene (INN-style spelling)", "Serophene (historical brand discussion)", "CC / Clom (clinic and forum shorthand)", "Clomiphene citrate USP 50 mg tablets" ], "type": "Non-peptide", "category": "Hormone modulators", "goals_use_cases": [ "hormone axis", "fertility discussion", "PCT discussion", "libido", "secondary hypogonadism discussion", "ovulation induction (approved female use)", "TRT alternative (discussed)", "energy / vitality (discussed)", "male infertility / oligospermia discussion", "sperm-parameter preservation vs exogenous T", "post-AAS HPTA restart talk" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "clomiphene", "Clomiphene citrate", "Clomid (brand)", "Clomifene (INN-style spelling)", "Serophene (historical brand discussion)", "CC / Clom (clinic and forum shorthand)", "hormone axis", "fertility discussion", "pct discussion", "libido", "secondary hypogonadism discussion", "ovulation induction (approved female use)" ], "feel_search": [ "hormone axis", "fertility discussion", "pct discussion", "libido", "secondary hypogonadism discussion", "ovulation induction (approved female use)" ], "summary": "Clomiphene (Clomid) is an oral selective estrogen receptor modulator used for ovulation induction and discussed in male fertility and testosterone care.", "search_blob": "clomiphene clomiphene clomid clomifene clomiphene citrate clomid (brand) clomifene (inn-style spelling) serophene (historical brand discussion) cc / clom (clinic and forum shorthand) clomiphene citrate usp 50 mg tablets clomiphene clomiphene citrate clomid (brand) clomifene (inn-style spelling) serophene (historical brand discussion) cc / clom (clinic and forum shorthand) hormone axis fertility discussion pct discussion libido secondary hypogonadism discussion ovulation induction (approved female use) hormone axis fertility discussion pct discussion libido secondary hypogonadism discussion ovulation induction (approved female use) trt alternative (discussed) energy / vitality (discussed) male infertility / oligospermia discussion sperm-parameter preservation vs exogenous t post-aas hpta restart talk hormone axis fertility discussion pct discussion libido secondary hypogonadism discussion ovulation induction (approved female use) clomiphene (clomid) is an oral selective estrogen receptor modulator used for ovulation induction and discussed in male fertility and testosterone care. a male-fertility thread includes low drive, depressed mood or irritability during use. one continuing user reports no depression but less energy than on testosterone. clomiphene is an oral compound people look up for fertility. some note early energy or libido ticks; many feel nothing yet. community, clinic, and trial ranges are descriptive \u2014 not dosing advice, not a prescription, not a claim of safety for unsupervised use. hormone modulators non-peptide systemic systemic oral serm \u2014 a mixture of enclomiphene and longer-persisting zuclomiphene changes hypothalamic/pituitary estrogen feedback. systemic whole-body circulating", "legal_class": null }, { "id": 138, "slug": "cabergoline", "name": "Cabergoline", "aliases": [ "Dostinex", "caber", "Dostinex (Pfizer brand)", "caber (forum shorthand)", "Cabaser (some Parkinson\u2019s-market branding)", "Cabgolin (Sun Pharma generic branding, discussed)", "Apo-Cabergoline / ACT Cabergoline (Canadian generics)", "Cabergoline tablets 0.5 mg (scored)" ], "type": "Non-peptide", "category": "Hormone modulators", "goals_use_cases": [ "libido", "prolactin discussion", "libido adjacency", "prolactin control / hyperprolactinemia discussion", "libido / sexual function when prolactin is high", "AAS 19-nor adjacency (nandrolone / trenbolone prolactin lore)", "galactorrhea / lactation-type sides discussion", "pituitary prolactinoma research context", "post-cycle / on-cycle hormone side-management talk", "endocrine research (D2 agonist class)", "vs bromocriptine / pramipexole comparison searches" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "cabergoline", "Dostinex (Pfizer brand)", "caber (forum shorthand)", "Cabaser (some Parkinson\u2019s-market branding)", "Cabgolin (Sun Pharma generic branding, discussed)", "Apo-Cabergoline / ACT Cabergoline (Canadian generics)", "prolactin control / hyperprolactinemia discussion", "libido / sexual function when prolactin is high", "aas 19-nor adjacency (nandrolone / trenbolone prolactin lore)", "galactorrhea / lactation-type sides discussion", "pituitary prolactinoma research context", "post-cycle / on-cycle hormone side-management talk" ], "feel_search": [ "prolactin control / hyperprolactinemia discussion", "libido / sexual function when prolactin is high", "aas 19-nor adjacency (nandrolone / trenbolone prolactin lore)", "galactorrhea / lactation-type sides discussion", "pituitary prolactinoma research context", "post-cycle / on-cycle hormone side-management talk" ], "summary": "Cabergoline (Dostinex) is a long-acting dopamine D2 agonist used to lower prolactin, including in prolactinoma care.", "search_blob": "cabergoline cabergoline dostinex caber dostinex (pfizer brand) caber (forum shorthand) cabaser (some parkinson\u2019s-market branding) cabgolin (sun pharma generic branding, discussed) apo-cabergoline / act cabergoline (canadian generics) cabergoline tablets 0.5 mg (scored) cabergoline dostinex (pfizer brand) caber (forum shorthand) cabaser (some parkinson\u2019s-market branding) cabgolin (sun pharma generic branding, discussed) apo-cabergoline / act cabergoline (canadian generics) prolactin control / hyperprolactinemia discussion libido / sexual function when prolactin is high aas 19-nor adjacency (nandrolone / trenbolone prolactin lore) galactorrhea / lactation-type sides discussion pituitary prolactinoma research context post-cycle / on-cycle hormone side-management talk libido prolactin discussion libido adjacency prolactin control / hyperprolactinemia discussion libido / sexual function when prolactin is high aas 19-nor adjacency (nandrolone / trenbolone prolactin lore) galactorrhea / lactation-type sides discussion pituitary prolactinoma research context post-cycle / on-cycle hormone side-management talk endocrine research (d2 agonist class) vs bromocriptine / pramipexole comparison searches prolactin control / hyperprolactinemia discussion libido / sexual function when prolactin is high aas 19-nor adjacency (nandrolone / trenbolone prolactin lore) galactorrhea / lactation-type sides discussion pituitary prolactinoma research context post-cycle / on-cycle hormone side-management talk cabergoline (dostinex) is a long-acting dopamine d2 agonist used to lower prolactin, including in prolactinoma care. one patient describes relief of prolactinoma symptoms alongside headache, fatigue, brain fog and mood changes in week three. illness and life stress complicate attribution. people discuss prolactin, libido changes with cabergoline, an oral medicine. driving prolactin too low is a recurring \u201cflat libido\u201d complaint. hormone modulators non-peptide systemic oral dopamine agonist that lowers prolactin, with effects beyond the pituitary including dizziness, sleepiness and impulse-control changes. systemic whole-body circulating", "legal_class": null }, { "id": 139, "slug": "bpc-oral-argyline-adjacent", "name": "Oral BPC-157 formulations (arginate/salt debates)", "aliases": [ "BPC arginate", "stable oral BPC", "BPC-157 arginate salt", "BPC arginine salt", "Arg-BPC", "Pentadeca arginate", "PDA (pentadeca arginate)", "Bepecin di-L-arginine salt", "stable gastric BPC-157 (oral framing)", "oral BPC-157", "BPC-157 capsules", "BPC Rapid / BPC Delayed (capsule branding talk)", "Argyline (common misspelling; not Argireline skincare)" ], "type": "Peptide", "category": "Healing & repair", "goals_use_cases": [ "gut health", "recovery", "GI lining support (discussed)", "NSAID-related gut irritation talk", "IBS / IBD forum talk (not approved therapy)", "leaky-gut forum framing", "recovery (route-debated)", "injury repair (oral vs inject debate)", "soft-tissue healing (route comparison)", "inflammation (discussed)", "needle-free peptide interest", "maintenance after injectable block (discussed)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Mixed", "misspellings_search_terms": [ "bpc-oral-argyline-adjacent", "bpc oral argyline adjacent", "bpcoralargylineadjacent", "Oral BPC-157 formulations (arginate/salt debates)", "oral-bpc-157-formulations-(arginate/salt-debates)", "BPC arginate", "gut health", "gi lining support (discussed)", "nsaid-related gut irritation talk", "ibs / ibd forum talk (not approved therapy)", "leaky-gut forum framing", "recovery (route-debated)" ], "feel_search": [ "gut health", "gi lining support (discussed)", "nsaid-related gut irritation talk", "ibs / ibd forum talk (not approved therapy)", "leaky-gut forum framing", "recovery (route-debated)" ], "summary": "Oral BPC-157 products contain the same research peptide in capsule or other oral forms; arginate and acetate describe different salts.", "search_blob": "oral bpc-157 formulations (arginate/salt debates) bpc-oral-argyline-adjacent bpc arginate stable oral bpc bpc-157 arginate salt bpc arginine salt arg-bpc pentadeca arginate pda (pentadeca arginate) bepecin di-l-arginine salt stable gastric bpc-157 (oral framing) oral bpc-157 bpc-157 capsules bpc rapid / bpc delayed (capsule branding talk) argyline (common misspelling; not argireline skincare) bpc-oral-argyline-adjacent bpc oral argyline adjacent bpcoralargylineadjacent oral bpc-157 formulations (arginate/salt debates) oral-bpc-157-formulations-(arginate/salt-debates) bpc arginate gut health gi lining support (discussed) nsaid-related gut irritation talk ibs / ibd forum talk (not approved therapy) leaky-gut forum framing recovery (route-debated) gut health recovery gi lining support (discussed) nsaid-related gut irritation talk ibs / ibd forum talk (not approved therapy) leaky-gut forum framing recovery (route-debated) injury repair (oral vs inject debate) soft-tissue healing (route comparison) inflammation (discussed) needle-free peptide interest maintenance after injectable block (discussed) gut health gi lining support (discussed) nsaid-related gut irritation talk ibs / ibd forum talk (not approved therapy) leaky-gut forum framing recovery (route-debated) oral bpc-157 products contain the same research peptide in capsule or other oral forms; arginate and acetate describe different salts. one oral arginate user describes better sleep and less pain, then adds injections at week three. that later comparison cannot establish oral-versus-injected equivalence. oral bpc-157 formulations (arginate/salt debates) is a peptide for gut. common gi checkpoint \u2014 \u201cis breakfast less hostile?\u201d healing & repair peptide mixed mixed and contested. mixed local systemic", "legal_class": null }, { "id": 140, "slug": "ghk-without-copper", "name": "GHK (without copper)", "aliases": [ "GHK peptide free base discussion", "GHK free base", "Free GHK", "GHK peptide (no copper)", "glycyl-L-histidyl-L-lysine", "Gly-His-Lys", "GHK tripeptide free form", "tripeptide-1 (cosmetic INCI free form)", "copper-free GHK", "GHK basic", "GHK alone" ], "type": "Peptide", "category": "Skin, hair & tissue remodeling", "goals_use_cases": [ "skin/hair", "recovery", "tissue remodeling discussion", "anti-aging discussion", "wound narratives", "copper-chelation / copper-avoidance interest", "cosmetic peptide comparison (free vs Cu complex)", "label / COA identity checks (wrong-product buys)", "stem-cell niche research talk (free vs Cu differentiation lore)", "research-only free-GHK animal cognition / gene work" ], "delivery_methods": [ "topical", "injection discussion" ], "discussion_popularity": "Emerging", "reach": "Mixed", "misspellings_search_terms": [ "ghk-without-copper", "ghk without copper", "ghkwithoutcopper", "GHK (without copper)", "ghk-(without-copper)", "GHK free base", "skin/hair", "recovery", "tissue remodeling discussion", "anti-aging discussion", "wound narratives", "copper-chelation / copper-avoidance interest" ], "feel_search": [ "skin/hair", "recovery", "tissue remodeling discussion", "anti-aging discussion", "wound narratives", "copper-chelation / copper-avoidance interest" ], "summary": "Copper-free GHK is the peptide part of GHK-Cu without copper already attached; free-GHK reports need to be kept separate from copper-peptide experiences.", "search_blob": "ghk (without copper) ghk-without-copper ghk peptide free base discussion ghk free base free ghk ghk peptide (no copper) glycyl-l-histidyl-l-lysine gly-his-lys ghk tripeptide free form tripeptide-1 (cosmetic inci free form) copper-free ghk ghk basic ghk alone ghk-without-copper ghk without copper ghkwithoutcopper ghk (without copper) ghk-(without-copper) ghk free base skin/hair recovery tissue remodeling discussion anti-aging discussion wound narratives copper-chelation / copper-avoidance interest skin/hair recovery tissue remodeling discussion anti-aging discussion wound narratives copper-chelation / copper-avoidance interest cosmetic peptide comparison (free vs cu complex) label / coa identity checks (wrong-product buys) stem-cell niche research talk (free vs cu differentiation lore) research-only free-ghk animal cognition / gene work skin/hair recovery tissue remodeling discussion anti-aging discussion wound narratives copper-chelation / copper-avoidance interest copper-free ghk is the peptide part of ghk-cu without copper already attached; free-ghk reports need to be kept separate from copper-peptide experiences. ghk (without copper) is a peptide people look up for skin. free-only users more often report subtle or disappointing skin change. skin, hair & tissue remodeling peptide mixed mixed \u2014 most free-ghk talk is topical, but sparse systemic injection reports and animal ip studies exist; do not substitute ghk-cu data. mixed local systemic", "legal_class": null }, { "id": 141, "slug": "ahk-cu", "name": "AHK-Cu", "aliases": [ "AHK copper peptide", "Ala-His-Lys copper", "AHK-Cu copper tripeptide", "L-alanyl-L-histidyl-L-lysine-Cu2+", "copper AHK", "copper tripeptide-3 (cosmetic INCI / supplier contexts)", "tripeptide-copper complex (AHK context)", "Ala-His-Lys-Cu" ], "type": "Peptide", "category": "Skin, hair & tissue remodeling", "goals_use_cases": [ "skin/hair", "hair density narratives", "scalp / follicle discussion", "aesthetic remodeling", "anti-aging discussion (by analogy to GHK-Cu)", "cosmetic copper-peptide interest", "DIY topical hair-serum culture", "GHK-Cu comparison / dual-copper stacks" ], "delivery_methods": [ "topical" ], "discussion_popularity": "Emerging", "reach": "Local", "misspellings_search_terms": [ "ahk-cu", "ahk cu", "ahkcu", "AHK copper peptide", "Ala-His-Lys copper", "AHK-Cu copper tripeptide", "scalp serum", "copper peptide hair", "tiktok inject", "dual copper", "ordinary serum", "blue tint", "vs ghk", "copper tripeptide-3" ], "feel_search": [ "scalp serum", "copper peptide hair", "tiktok inject", "dual copper", "ordinary serum", "blue tint", "vs ghk", "copper tripeptide-3" ], "summary": "AHK-Cu is a copper-binding tripeptide studied for hair biology and used in experimental topical hair products.", "search_blob": "ahk-cu ahk-cu ahk copper peptide ala-his-lys copper ahk-cu copper tripeptide l-alanyl-l-histidyl-l-lysine-cu2+ copper ahk copper tripeptide-3 (cosmetic inci / supplier contexts) tripeptide-copper complex (ahk context) ala-his-lys-cu ahk-cu ahk cu ahkcu ahk copper peptide ala-his-lys copper ahk-cu copper tripeptide scalp serum copper peptide hair tiktok inject dual copper ordinary serum blue tint vs ghk copper tripeptide-3 skin/hair hair density narratives scalp / follicle discussion aesthetic remodeling anti-aging discussion (by analogy to ghk-cu) cosmetic copper-peptide interest diy topical hair-serum culture ghk-cu comparison / dual-copper stacks scalp serum copper peptide hair tiktok inject dual copper ordinary serum blue tint vs ghk copper tripeptide-3 ahk-cu is a copper-binding tripeptide studied for hair biology and used in experimental topical hair products. one topical user reports baby hairs and reduced shedding after months, while also using minoxidil, alfatradiol and microneedling. ahk-cu's contribution is unclear. ahk-cu is a peptide people look up for hair. occasional \u201cnew hairs\u201d or thicker feel claims appear in enthusiastic posts \u2014 still unblinded and often stacked; treat as anecdote. the 2026 loud fight is topical vs tiktok pin. the hair paper was dish follicles, not an injection study. skin, hair & tissue remodeling peptide local mainly topical scalp use; sparse injection accounts describe a different, poorly characterized exposure. local site pin topical", "legal_class": null }, { "id": 142, "slug": "copper-tripeptide-variants", "name": "Copper tripeptide variants (cosmetic research)", "aliases": [ "copper peptides class", "Cu-GHK family products", "copper tripeptide-1 family", "GHK-Cu analogs / variants", "AHK-Cu (related copper tripeptide)", "copper tripeptide-3 (AHK-Cu cosmetic talk)", "cosmetic copper peptides", "carrier copper peptides", "GHK without copper (adjacent, not Cu-complex)" ], "type": "Peptide", "category": "Skin, hair & tissue remodeling", "goals_use_cases": [ "skin/hair", "anti-aging discussion", "collagen / firmness talk", "texture & tone narratives", "scalp / hair appearance", "cosmetic matrix remodeling", "post-procedure recovery talk", "wound / scar adjacency (literature more than DIY)", "Glow / KLOW stack copper leg (injectable adjacency)" ], "delivery_methods": [ "topical" ], "discussion_popularity": "Emerging", "reach": "Local", "misspellings_search_terms": [ "copper-tripeptide-variants", "copper tripeptide variants", "coppertripeptidevariants", "Copper tripeptide variants (cosmetic research)", "copper-tripeptide-variants-(cosmetic-research)", "copper peptides class", "skin/hair", "anti-aging discussion", "collagen / firmness talk", "texture & tone narratives", "scalp / hair appearance", "cosmetic matrix remodeling" ], "feel_search": [ "skin/hair", "anti-aging discussion", "collagen / firmness talk", "texture & tone narratives", "scalp / hair appearance", "cosmetic matrix remodeling" ], "summary": "Copper peptide products include different molecules such as GHK-Cu and AHK-Cu, used in skin and hair cosmetics and experimental preparations.", "search_blob": "copper tripeptide variants (cosmetic research) copper-tripeptide-variants copper peptides class cu-ghk family products copper tripeptide-1 family ghk-cu analogs / variants ahk-cu (related copper tripeptide) copper tripeptide-3 (ahk-cu cosmetic talk) cosmetic copper peptides carrier copper peptides ghk without copper (adjacent, not cu-complex) copper-tripeptide-variants copper tripeptide variants coppertripeptidevariants copper tripeptide variants (cosmetic research) copper-tripeptide-variants-(cosmetic-research) copper peptides class skin/hair anti-aging discussion collagen / firmness talk texture & tone narratives scalp / hair appearance cosmetic matrix remodeling skin/hair anti-aging discussion collagen / firmness talk texture & tone narratives scalp / hair appearance cosmetic matrix remodeling post-procedure recovery talk wound / scar adjacency (literature more than diy) glow / klow stack copper leg (injectable adjacency) skin/hair anti-aging discussion collagen / firmness talk texture & tone narratives scalp / hair appearance cosmetic matrix remodeling copper peptide products include different molecules such as ghk-cu and ahk-cu, used in skin and hair cosmetics and experimental preparations. a ghk-cu serum user reports new fine lines after about ten days and stops. that experience does not establish the same reaction for ahk-cu or injected products. copper tripeptide variants (cosmetic research) are a peptide class people look up for skin. multi-week firmer look and fine-line talk; photo windows often 8\u201312 weeks. skin, hair & tissue remodeling peptide local mostly local topicals; systemic injection talk belongs chiefly to ghk-cu or glow/klow blends, not every copper-peptide variant. local site pin topical", "legal_class": null }, { "id": 143, "slug": "mots-c-analogs", "name": "MOTS-c analogs / MDP class talk", "aliases": [ "mitochondrial-derived peptide class", "MOTS-c analogs", "CB4211", "CB-4211", "CB 4211", "MDP class", "MDP peptides", "MOTS-c derivatives", "mitochondrial ORF peptide analogs", "mitochondria based therapeutics", "MBT peptides (CohBar)", "CB5138", "CB5064 analogs", "MBT5 analogs", "MOTS-c analogue" ], "type": "Peptide", "category": "Mitochondrial & metabolic peptides", "goals_use_cases": [ "metabolic health", "longevity", "insulin sensitivity (discussed)", "longevity / healthspan", "mitochondrial function", "NAFLD / NASH / fatty liver research interest", "obesity / weight research interest (analog path)", "exercise mimetic narratives", "healthy aging / healthspan", "body recomposition (discussed)", "glucose handling / metabolic flexibility", "fibrosis research interest (other CohBar MDP assets)", "vendor \u201cimproved MOTS-c\u201d label shopping" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "mots-c-analogs", "mots c analogs", "motscanalogs", "MOTS-c analogs / MDP class talk", "mots-c-analogs-/-mdp-class-talk", "MOTS-c analogs", "metabolic health", "insulin sensitivity (discussed)", "longevity / healthspan", "mitochondrial function", "nafld / nash / fatty liver research interest", "obesity / weight research interest (analog path)" ], "feel_search": [ "metabolic health", "insulin sensitivity (discussed)", "longevity / healthspan", "mitochondrial function", "nafld / nash / fatty liver research interest", "obesity / weight research interest (analog path)" ], "summary": "MOTS-c analogs are modified mitochondrial-peptide candidates, including CB4211; this is a family of products, not one interchangeable compound.", "search_blob": "mots-c analogs / mdp class talk mots-c-analogs mitochondrial-derived peptide class mots-c analogs cb4211 cb-4211 cb 4211 mdp class mdp peptides mots-c derivatives mitochondrial orf peptide analogs mitochondria based therapeutics mbt peptides (cohbar) cb5138 cb5064 analogs mbt5 analogs mots-c analogue mots-c-analogs mots c analogs motscanalogs mots-c analogs / mdp class talk mots-c-analogs-/-mdp-class-talk mots-c analogs metabolic health insulin sensitivity (discussed) longevity / healthspan mitochondrial function nafld / nash / fatty liver research interest obesity / weight research interest (analog path) metabolic health longevity insulin sensitivity (discussed) longevity / healthspan mitochondrial function nafld / nash / fatty liver research interest obesity / weight research interest (analog path) exercise mimetic narratives healthy aging / healthspan body recomposition (discussed) glucose handling / metabolic flexibility fibrosis research interest (other cohbar mdp assets) vendor \u201cimproved mots-c\u201d label shopping metabolic health insulin sensitivity (discussed) longevity / healthspan mitochondrial function nafld / nash / fatty liver research interest obesity / weight research interest (analog path) mots-c analogs are modified mitochondrial-peptide candidates, including cb4211; this is a family of products, not one interchangeable compound. analog-specific experience is sparse. most shared energy or fatigue stories concern parent mots-c; cb4211 injection-site reactions are a separate clinical finding. mots-c analogs is a peptide people look up for longevity. \u201cexercise in a vial\u201d is community shorthand for the class \u2014 not a proven training substitute. mitochondrial & metabolic peptides peptide systemic systemic \u2014 whole-body energy, insulin, and mitochondrial signaling class. systemic whole-body circulating", "legal_class": null }, { "id": 144, "slug": "5-aminoimidazole-class", "name": "AICAR (AMPK discourse)", "aliases": [ "AICAR", "acadesine", "AICAr", "AICA-R", "AICA riboside", "AICA ribonucleoside", "5-aminoimidazole-4-carboxamide-1-\u03b2-D-ribofuranoside", "5-aminoimidazole-4-carboxamide riboside", "5-amino-4-imidazolecarboxamide ribonucleoside", "AICA ribonucleotide (endogenous phosphorylated form / nomenclature clash)", "ZMP (intracellular AICAR monophosphate / Z-nucleotide)", "Z-riboside", "CAS 2627-69-2", "exercise-in-a-pill AICAR (media nickname)" ], "type": "Non-peptide", "category": "Metabolic research compounds", "goals_use_cases": [ "endurance", "metabolic health", "performance", "endurance / running capacity (preclinical + community)", "exercise-mimetic / \u201cexercise-in-a-pill\u201d narrative", "fat oxidation / metabolic reprogramming (preclinical)", "AMPK pathway research tool", "insulin sensitivity / glucose uptake research (preclinical + limited human IV)", "mitochondrial / oxidative muscle gene programs (preclinical)", "performance continuity / steady-state cardio assist (community)", "body recomposition assist under diet (community, weak solo signal)", "cardiac ischemia / CABG historical drug development (acadesine)", "hematologic malignancy research history (CLL, MDS/AML IV trials)", "anti-doping / WADA metabolic-modulator literacy" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "5-aminoimidazole-class", "5 aminoimidazole class", "5aminoimidazoleclass", "AICAR (AMPK discourse)", "aicar-(ampk-discourse)", "AICAR", "endurance / running capacity (preclinical + community)", "exercise-mimetic / \u201cexercise-in-a-pill\u201d narrative", "fat oxidation / metabolic reprogramming (preclinical)", "ampk pathway research tool", "insulin sensitivity / glucose uptake research (preclinical + limited human iv)", "mitochondrial / oxidative muscle gene programs (preclinical)" ], "feel_search": [ "endurance / running capacity (preclinical + community)", "exercise-mimetic / \u201cexercise-in-a-pill\u201d narrative", "fat oxidation / metabolic reprogramming (preclinical)", "ampk pathway research tool", "insulin sensitivity / glucose uptake research (preclinical + limited human iv)", "mitochondrial / oxidative muscle gene programs (preclinical)" ], "summary": "AICAR, also called acadesine, is a non-peptide nucleoside studied for metabolic signaling and discussed as an endurance aid.", "search_blob": "aicar (ampk discourse) 5-aminoimidazole-class aicar acadesine aicar aica-r aica riboside aica ribonucleoside 5-aminoimidazole-4-carboxamide-1-\u03b2-d-ribofuranoside 5-aminoimidazole-4-carboxamide riboside 5-amino-4-imidazolecarboxamide ribonucleoside aica ribonucleotide (endogenous phosphorylated form / nomenclature clash) zmp (intracellular aicar monophosphate / z-nucleotide) z-riboside cas 2627-69-2 exercise-in-a-pill aicar (media nickname) 5-aminoimidazole-class 5 aminoimidazole class 5aminoimidazoleclass aicar (ampk discourse) aicar-(ampk-discourse) aicar endurance / running capacity (preclinical + community) exercise-mimetic / \u201cexercise-in-a-pill\u201d narrative fat oxidation / metabolic reprogramming (preclinical) ampk pathway research tool insulin sensitivity / glucose uptake research (preclinical + limited human iv) mitochondrial / oxidative muscle gene programs (preclinical) endurance metabolic health performance endurance / running capacity (preclinical + community) exercise-mimetic / \u201cexercise-in-a-pill\u201d narrative fat oxidation / metabolic reprogramming (preclinical) ampk pathway research tool insulin sensitivity / glucose uptake research (preclinical + limited human iv) mitochondrial / oxidative muscle gene programs (preclinical) performance continuity / steady-state cardio assist (community) body recomposition assist under diet (community, weak solo signal) cardiac ischemia / cabg historical drug development (acadesine) hematologic malignancy research history (cll, mds/aml iv trials) anti-doping / wada metabolic-modulator literacy endurance / running capacity (preclinical + community) exercise-mimetic / \u201cexercise-in-a-pill\u201d narrative fat oxidation / metabolic reprogramming (preclinical) ampk pathway research tool insulin sensitivity / glucose uptake research (preclinical + limited human iv) mitochondrial / oxidative muscle gene programs (preclinical) aicar, also called acadesine, is a non-peptide nucleoside studied for metabolic signaling and discussed as an endurance aid. the inspected stacked-use log reports little overall difference and credits the speedy, hot feeling to helios. it does not establish an aicar-only feel. aicar is a compound people look up for endurance. weak as a solo agent in honest threads; any scale movement usually co-attributed to deficit, cardio volume, and gw/sarm stacks. metabolic research compounds non-peptide systemic systemic \u2014 aicar/acadesine is a nucleoside converted inside cells to zmp; not a peptide, local endurance injection or class-wide exposure model. systemic whole-body circulating", "legal_class": null }, { "id": 145, "slug": "gw0742", "name": "GW0742", "aliases": [ "PPAR\u03b4 agonist research", "GW-0742", "GW 0742", "GW610742", "GW-610742", "Fitorine", "Lipoline (forum trade nicknames)", "Super Cardarine (community nickname)", "Advanced Cardio (vendor branding)" ], "type": "Non-peptide", "category": "Metabolic research compounds", "goals_use_cases": [ "endurance", "fat loss discussion", "endurance / cardio capacity discussion", "fat loss / recomp adjacency (community)", "metabolic / fuel-preference research", "lipid profile / reverse cholesterol transport (preclinical)", "insulin-sensitivity / HOMA-IR research (preclinical)", "inflammation models (preclinical)", "performance / non-androgenic cutting stacks", "Cardarine (GW501516) alternative or sequential trial" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "gw0742", "GW-0742", "GW 0742", "GW610742", "GW-610742", "Fitorine", "endurance / cardio capacity discussion", "fat loss / recomp adjacency (community)", "metabolic / fuel-preference research", "lipid profile / reverse cholesterol transport (preclinical)", "insulin-sensitivity / homa-ir research (preclinical)", "inflammation models (preclinical)" ], "feel_search": [ "endurance / cardio capacity discussion", "fat loss / recomp adjacency (community)", "metabolic / fuel-preference research", "lipid profile / reverse cholesterol transport (preclinical)", "insulin-sensitivity / homa-ir research (preclinical)", "inflammation models (preclinical)" ], "summary": "GW0742 is an experimental PPAR-delta/beta activator related to cardarine, discussed for endurance and fat metabolism.", "search_blob": "gw0742 gw0742 ppar\u03b4 agonist research gw-0742 gw 0742 gw610742 gw-610742 fitorine lipoline (forum trade nicknames) super cardarine (community nickname) advanced cardio (vendor branding) gw0742 gw-0742 gw 0742 gw610742 gw-610742 fitorine endurance / cardio capacity discussion fat loss / recomp adjacency (community) metabolic / fuel-preference research lipid profile / reverse cholesterol transport (preclinical) insulin-sensitivity / homa-ir research (preclinical) inflammation models (preclinical) endurance fat loss discussion endurance / cardio capacity discussion fat loss / recomp adjacency (community) metabolic / fuel-preference research lipid profile / reverse cholesterol transport (preclinical) insulin-sensitivity / homa-ir research (preclinical) inflammation models (preclinical) performance / non-androgenic cutting stacks cardarine (gw501516) alternative or sequential trial endurance / cardio capacity discussion fat loss / recomp adjacency (community) metabolic / fuel-preference research lipid profile / reverse cholesterol transport (preclinical) insulin-sensitivity / homa-ir research (preclinical) inflammation models (preclinical) gw0742 is an experimental ppar-delta/beta activator related to cardarine, discussed for endurance and fat metabolism. endurance reports are mixed, including no benefit. some describe headache, nausea, fatigue or racing/irregular heartbeat; later positive accounts often involve changed schedules or other compounds. gw0742 is a compound people look up for endurance. longer sessions, easier steady-state cardio, less \u201cgas tank empty\u201d feel; public log volume is much smaller. metabolic research compounds non-peptide systemic systemic \u2014 a whole-body selective ppar\u03b4/\u03b2 agonist discussed as shifting muscle fuel use toward fatty-acid oxidation, not a local or injection-site agent. systemic whole-body circulating", "legal_class": null }, { "id": 147, "slug": "acp-105", "name": "ACP-105", "aliases": [ "ACP105", "ACP 105", "Acadia SARM ACP-105", "non-steroidal SARM ACP-105", "2-chloro-4-[(3-endo)-3-hydroxy-3-methyl-8-azabicyclo[3.2.1]oct-8-yl]-3-methylbenzonitrile", "CAS 1048998-11-3" ], "type": "Non-peptide", "category": "SARMs (adjacent discourse)", "goals_use_cases": [ "muscle growth", "performance", "lean mass (discussed)", "recomposition (discussed)", "cutting / dry look (discussed)", "bone support (preclinical interest)", "strength continuity (discussed)", "body composition", "milder oral SARM alternative (community framing)", "age-related cognitive decline research context (preclinical only)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "acp-105", "acp 105", "acp105", "Acadia SARM ACP-105", "non-steroidal SARM ACP-105", "2-chloro-4-[(3-endo)-3-hydroxy-3-methyl-8-azabicyclo[3.2.1]oct-8-yl]-3-methylbenzonitrile", "muscle growth", "performance", "lean mass (discussed)", "recomposition (discussed)", "cutting / dry look (discussed)", "bone support (preclinical interest)" ], "feel_search": [ "muscle growth", "performance", "lean mass (discussed)", "recomposition (discussed)", "cutting / dry look (discussed)", "bone support (preclinical interest)" ], "summary": "ACP-105 is an oral SARM discussed for lean recomp, pumps and a dry look. Modest lean/strength talk closer to ostarine.", "search_blob": "acp-105 acp-105 acp105 acp 105 acadia sarm acp-105 non-steroidal sarm acp-105 2-chloro-4-[(3-endo)-3-hydroxy-3-methyl-8-azabicyclo[3.2.1]oct-8-yl]-3-methylbenzonitrile cas 1048998-11-3 acp-105 acp 105 acp105 acadia sarm acp-105 non-steroidal sarm acp-105 2-chloro-4-[(3-endo)-3-hydroxy-3-methyl-8-azabicyclo[3.2.1]oct-8-yl]-3-methylbenzonitrile muscle growth performance lean mass (discussed) recomposition (discussed) cutting / dry look (discussed) bone support (preclinical interest) muscle growth performance lean mass (discussed) recomposition (discussed) cutting / dry look (discussed) bone support (preclinical interest) strength continuity (discussed) body composition milder oral sarm alternative (community framing) age-related cognitive decline research context (preclinical only) muscle growth performance lean mass (discussed) recomposition (discussed) cutting / dry look (discussed) bone support (preclinical interest) acp-105 is an oral sarm discussed for lean recomp, pumps and a dry look. modest lean/strength talk closer to ostarine. a detailed log describes early headache, restless sleep and energy, then gym pumps. illness and other medicines complicate its later adverse-event account. acp-105 is an oral sarm discussed for lean recomp, pumps and a dry look. modest lean/strength talk closer to ostarine. forum mg charts, 12\u201316 h half-life memes, and \u201cmilder than lgd\u201d lore are discussion data \u2014 not verified human pk or head-to-head trials. sarms (adjacent discourse) non-peptide systemic systemic oral sarm \u2014 muscle/bone selectivity comes from preclinical work, not local targeting or proof of a safe steroid replacement. systemic whole-body circulating", "legal_class": null }, { "id": 148, "slug": "ligandrol-recomp-stacks", "name": "Ligandrol recomp stacks (SARM multi-agent culture)", "aliases": [ "SARM stacks", "RAD+LGD culture threads", "LGD recomp stacks", "Ligandrol stack", "LGD-4033 stacks", "LGD + RAD stack", "LGD + ostarine stack", "LGD + Cardarine stack", "LGD + MK-677 stack", "SARM stack culture (multi-agent discussion unit)", "multi-SARM recomp cycle", "kitchen-sink SARM blend" ], "type": "Non-peptide", "category": "SARMs (adjacent discourse)", "goals_use_cases": [ "muscle growth", "performance", "fat loss", "body recomposition (simultaneous fat loss + muscle hold/gain, primary community framing)", "muscle growth / lean bulk with oral multi-agent stacks", "strength and progressive overload under deficit or near-maintenance", "cutting with muscle retention (community \u201chold size while cutting\u201d)", "performance / conditioning when Cardarine or similar is co-logged", "bulk-to-recomp and recomp-to-cut seasonal transitions", "\u201csteroid-like results without injectables\u201d marketing narrative (unproven safety equivalence)", "attribution of aesthetic look (fuller LGD vs drier RAD/ostarine typology)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "ligandrol-recomp-stacks", "ligandrol recomp stacks", "ligandrolrecompstacks", "Ligandrol recomp stacks (SARM multi-agent culture)", "ligandrol-recomp-stacks-(sarm-multi-agent-culture)", "SARM stacks", "body recomposition (simultaneous fat loss + muscle hold/gain, primary community framing)", "muscle growth / lean bulk with oral multi-agent stacks", "strength and progressive overload under deficit or near-maintenance", "cutting with muscle retention (community \u201chold size while cutting\u201d)", "performance / conditioning when cardarine or similar is co-logged", "bulk-to-recomp and recomp-to-cut seasonal transitions" ], "feel_search": [ "body recomposition (simultaneous fat loss + muscle hold/gain, primary community framing)", "muscle growth / lean bulk with oral multi-agent stacks", "strength and progressive overload under deficit or near-maintenance", "cutting with muscle retention (community \u201chold size while cutting\u201d)", "performance / conditioning when cardarine or similar is co-logged", "bulk-to-recomp and recomp-to-cut seasonal transitions" ], "summary": "Ligandrol recomp stacks are combinations built around LGD-4033, discussed for losing fat while retaining or gaining muscle; they are not one standardized product.", "search_blob": "ligandrol recomp stacks (sarm multi-agent culture) ligandrol-recomp-stacks sarm stacks rad+lgd culture threads lgd recomp stacks ligandrol stack lgd-4033 stacks lgd + rad stack lgd + ostarine stack lgd + cardarine stack lgd + mk-677 stack sarm stack culture (multi-agent discussion unit) multi-sarm recomp cycle kitchen-sink sarm blend ligandrol-recomp-stacks ligandrol recomp stacks ligandrolrecompstacks ligandrol recomp stacks (sarm multi-agent culture) ligandrol-recomp-stacks-(sarm-multi-agent-culture) sarm stacks body recomposition (simultaneous fat loss + muscle hold/gain, primary community framing) muscle growth / lean bulk with oral multi-agent stacks strength and progressive overload under deficit or near-maintenance cutting with muscle retention (community \u201chold size while cutting\u201d) performance / conditioning when cardarine or similar is co-logged bulk-to-recomp and recomp-to-cut seasonal transitions muscle growth performance fat loss body recomposition (simultaneous fat loss + muscle hold/gain, primary community framing) muscle growth / lean bulk with oral multi-agent stacks strength and progressive overload under deficit or near-maintenance cutting with muscle retention (community \u201chold size while cutting\u201d) performance / conditioning when cardarine or similar is co-logged bulk-to-recomp and recomp-to-cut seasonal transitions \u201csteroid-like results without injectables\u201d marketing narrative (unproven safety equivalence) attribution of aesthetic look (fuller lgd vs drier rad/ostarine typology) body recomposition (simultaneous fat loss + muscle hold/gain, primary community framing) muscle growth / lean bulk with oral multi-agent stacks strength and progressive overload under deficit or near-maintenance cutting with muscle retention (community \u201chold size while cutting\u201d) performance / conditioning when cardarine or similar is co-logged bulk-to-recomp and recomp-to-cut seasonal transitions ligandrol recomp stacks are combinations built around lgd-4033, discussed for losing fat while retaining or gaining muscle; they are not one standardized product. reports depend on the partners: one lgd/ostarine user described definition and mostly water-weight gain, while another testosterone/lgd/rad user reported severe erectile dysfunction. there is no single stack response. ligandrol recomp stacks (sarm multi-agent culture) is an oral compound people look up for fat loss. named multi-sarm recomp stacks have no quality rcts. sarms (adjacent discourse) non-peptide systemic systemic oral multi-agent stacks \u2014 whole-body androgen-receptor (and often non-sarm adjunct) exposure. systemic whole-body circulating", "legal_class": null }, { "id": 149, "slug": "ta-65", "name": "TA-65", "aliases": [ "TA65", "cycloastragenol", "telomerase activation discussion", "TA-65MD", "TA-65 MD", "cycloastragenol (related active / class discussion)", "TAT2 (research synonym in older literature)", "Astragalus root extract (branded telomerase-activator product)", "telomerase activator 65", "T.A. Sciences TA-65", "CAG (cycloastragenol shorthand in literature)" ], "type": "Non-peptide", "category": "Longevity & cellular energy", "goals_use_cases": [ "longevity", "telomere discussion", "anti-aging discussion", "immune aging / immunosenescence talk", "cellular energy / vitality narratives", "healthspan biomarkers (discussed)", "metabolic syndrome marker interest", "post-MI immune / inflammation talk (clinical pilot)", "skin fitness narratives (oral minority; topical TA-65 for Skin product line)", "cardiovascular risk-marker interest (HDL / inflammation)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "ta-65", "ta 65", "ta65", "TA-65MD", "TA-65 MD", "cycloastragenol (related active / class discussion)", "longevity", "telomere discussion", "anti-aging discussion", "immune aging / immunosenescence talk", "cellular energy / vitality narratives", "healthspan biomarkers (discussed)" ], "feel_search": [ "longevity", "telomere discussion", "anti-aging discussion", "immune aging / immunosenescence talk", "cellular energy / vitality narratives", "healthspan biomarkers (discussed)" ], "summary": "TA-65 is a branded oral Astragalus-derived supplement marketed as a telomerase activator for longevity-related interests.", "search_blob": "ta-65 ta-65 ta65 cycloastragenol telomerase activation discussion ta-65md ta-65 md cycloastragenol (related active / class discussion) tat2 (research synonym in older literature) astragalus root extract (branded telomerase-activator product) telomerase activator 65 t.a. sciences ta-65 cag (cycloastragenol shorthand in literature) ta-65 ta 65 ta65 ta-65md ta-65 md cycloastragenol (related active / class discussion) longevity telomere discussion anti-aging discussion immune aging / immunosenescence talk cellular energy / vitality narratives healthspan biomarkers (discussed) longevity telomere discussion anti-aging discussion immune aging / immunosenescence talk cellular energy / vitality narratives healthspan biomarkers (discussed) metabolic syndrome marker interest post-mi immune / inflammation talk (clinical pilot) skin fitness narratives (oral minority; topical ta-65 for skin product line) cardiovascular risk-marker interest (hdl / inflammation) longevity telomere discussion anti-aging discussion immune aging / immunosenescence talk cellular energy / vitality narratives healthspan biomarkers (discussed) ta-65 is a branded oral astragalus-derived supplement marketed as a telomerase activator for longevity-related interests. one older forum user described strength benefits that later faded, while also using another product and dealing with anemia. ta-65 is an oral compound people look up for longevity. energy/recovery anecdotes, if any, build slowly and are hard to isolate from concurrent nad, sleep, or training changes. longevity & cellular energy non-peptide systemic systemic oral telomerase-pathway supplement (branded cycloastragenol-class capsule); whole-body longevity and immune-aging talk. systemic whole-body circulating", "legal_class": null }, { "id": 150, "slug": "astaxanthin-biohack", "name": "Astaxanthin", "aliases": [ "astroxanthin misspelling common", "Haematococcus extract", "ASX", "AST", "AX", "Astaxanthine", "Astaxanthin (biohacking adjacency)", "Haematococcus pluvialis extract", "Haematococcus lacustris extract", "Natural astaxanthin (algae-derived)", "Synthetic astaxanthin", "Astaxanthin esters", "Astaxanthin mono-/diesters", "AstaREAL / BioAstin-style algal products (brand family talk)", "3S,3'S astaxanthin" ], "type": "Non-peptide", "category": "Antioxidant & performance adjacents", "goals_use_cases": [ "skin/hair", "recovery", "eye health discussion", "inflammation discussion", "skin/hair / photoaging adjacency", "recovery / DOMS discussion", "eye health / digital eye-strain discussion", "mild dry-eye discussion", "inflammation / oxidative-stress marker talk", "antioxidant support (discussed)", "UV / erythema resilience adjacency", "exercise endurance / cycling performance adjacency", "longevity / healthy aging (discussed)", "cognitive / psychomotor minority signal", "cardiometabolic marker adjacency (BP, lipids \u2014 sparse)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "astaxanthin-biohack", "astaxanthin biohack", "astaxanthinbiohack", "Astaxanthin", "ASX", "AST", "skin/hair / photoaging adjacency", "recovery / doms discussion", "eye health / digital eye-strain discussion", "mild dry-eye discussion", "inflammation / oxidative-stress marker talk", "antioxidant support (discussed)" ], "feel_search": [ "skin/hair / photoaging adjacency", "recovery / doms discussion", "eye health / digital eye-strain discussion", "mild dry-eye discussion", "inflammation / oxidative-stress marker talk", "antioxidant support (discussed)" ], "summary": "Astaxanthin is a red-orange carotenoid, usually sold in algae-derived capsules for skin, eye and antioxidant interests.", "search_blob": "astaxanthin astaxanthin-biohack astroxanthin misspelling common haematococcus extract asx ast ax astaxanthine astaxanthin (biohacking adjacency) haematococcus pluvialis extract haematococcus lacustris extract natural astaxanthin (algae-derived) synthetic astaxanthin astaxanthin esters astaxanthin mono-/diesters astareal / bioastin-style algal products (brand family talk) 3s,3's astaxanthin astaxanthin-biohack astaxanthin biohack astaxanthinbiohack astaxanthin asx ast skin/hair / photoaging adjacency recovery / doms discussion eye health / digital eye-strain discussion mild dry-eye discussion inflammation / oxidative-stress marker talk antioxidant support (discussed) skin/hair recovery eye health discussion inflammation discussion skin/hair / photoaging adjacency recovery / doms discussion eye health / digital eye-strain discussion mild dry-eye discussion inflammation / oxidative-stress marker talk antioxidant support (discussed) uv / erythema resilience adjacency exercise endurance / cycling performance adjacency longevity / healthy aging (discussed) cognitive / psychomotor minority signal cardiometabolic marker adjacency (bp, lipids \u2014 sparse) skin/hair / photoaging adjacency recovery / doms discussion eye health / digital eye-strain discussion mild dry-eye discussion inflammation / oxidative-stress marker talk antioxidant support (discussed) astaxanthin is a red-orange carotenoid, usually sold in algae-derived capsules for skin, eye and antioxidant interests. one gel-cap user reports early acne and workout changes, then worries about libido, while explicitly acknowledging placebo or nocebo. this is not proof of hormone suppression. astaxanthin is an oral compound people look up for skin. some clinical work notes improved mild\u2013moderate dry-eye symptom scores \u2014 does not replace ophthalmology care. antioxidant & performance adjacents non-peptide systemic systemic oral fat-soluble xanthophyll carotenoid (c40h52o4); lipoprotein-carried plasma exposure with tissue lag for skin/eyes/muscle. systemic whole-body circulating", "legal_class": null }, { "id": 151, "slug": "wolverine-stack", "name": "Wolverine stack", "aliases": [ "Wolverine blend", "BPC-157 + TB-500", "BPC TB stack", "wolverine peptide stack", "BPC/TB stack", "healing stack (BPC+TB)", "Wolverine peptide blend", "BPC-157/TB-500 combo" ], "type": "Peptide", "category": "Healing stacks (named blends)", "goals_use_cases": [ "recovery", "injury repair", "joints & tendons", "soft-tissue healing", "performance continuity", "inflammation discussion", "post-strain bounce-back", "ligament / tendon irritation talk", "mobility continuity under training load" ], "delivery_methods": [ "subcutaneous", "separate vials or pre-mixed blend" ], "discussion_popularity": "High", "reach": "Mixed", "misspellings_search_terms": [ "wolverine-stack", "wolverine stack", "wolverinestack", "Wolverine blend", "BPC-157 + TB-500", "BPC/TB stack", "injury", "tendon", "wolverine", "recovery", "pcac", "503a", "compounding", "fda approved", "wolverine nasal", "bpc tb nasal", "nasal", "site pin", "flu-ish" ], "feel_search": [ "injury", "tendon", "wolverine", "recovery", "nasal", "site pin", "flu-ish" ], "summary": "The Wolverine stack combines BPC-157 and TB-500, separately or in a blend, for injury and soft-tissue recovery interests.", "search_blob": "wolverine stack wolverine-stack wolverine blend bpc-157 + tb-500 bpc tb stack wolverine peptide stack bpc/tb stack healing stack (bpc+tb) wolverine peptide blend bpc-157/tb-500 combo wolverine-stack wolverine stack wolverinestack wolverine blend bpc-157 + tb-500 bpc/tb stack injury tendon wolverine recovery pcac 503a compounding fda approved wolverine nasal bpc tb nasal nasal site pin flu-ish recovery injury repair joints & tendons soft-tissue healing performance continuity inflammation discussion post-strain bounce-back ligament / tendon irritation talk mobility continuity under training load injury tendon wolverine recovery nasal site pin flu-ish the wolverine stack combines bpc-157 and tb-500, separately or in a blend, for injury and soft-tissue recovery interests. accounts include pain-free training, little change and worsened nerve-burning symptoms; neither ingredient's contribution is isolated. wolverine stack is a named blend for recovery. users report faster recovery from strains, tweaks, and training niggles vs rest alone \u2014 heavily confounded by deload and pt. pre-mixed vials hide the two different unit cultures (mcg vs mg). read both amounts. july 2026 pcac votes were on each peptide separately \u2014 not on a wolverine drug. healing stacks (named blends) peptide mixed mixed \u2014 bpc near the injury, tb as whole-body mobility. that\u2019s the forum split. mixed local systemic", "legal_class": null }, { "id": 152, "slug": "glow-stack", "name": "GLOW stack", "aliases": [ "Glow blend", "GLOW peptide", "GHK-Cu BPC-157 TB-500", "glow stack 70mg", "GHK-Cu + BPC-157 + TB-500", "GLOW 5:1:1", "50/10/10 blend", "GHK BPC TB blend", "Glow 70", "GLOW 50", "GLOW 70", "5:1:1 blend" ], "type": "Peptide", "category": "Healing stacks (named blends)", "goals_use_cases": [ "recovery", "skin/hair", "injury repair", "anti-aging discussion", "soft-tissue healing", "collagen discussion", "post-procedure aesthetic recovery", "wound/scar remodeling talk" ], "delivery_methods": [ "subcutaneous", "pre-mixed multi-peptide vial" ], "discussion_popularity": "High", "reach": "Mixed", "misspellings_search_terms": [ "glow-stack", "glow stack", "glowstack", "Glow blend", "GLOW peptide", "GHK-Cu + BPC-157 + TB-500", "skin", "glow", "sting", "recovery", "copper uglies", "glow 50", "glow 70", "glow drip" ], "feel_search": [ "skin", "glow", "sting", "recovery", "copper uglies", "glow 50", "glow 70", "glow drip" ], "summary": "GLOW combines GHK-Cu, BPC-157 and TB-500; people discuss the blend for skin appearance and injury recovery.", "search_blob": "glow stack glow-stack glow blend glow peptide ghk-cu bpc-157 tb-500 glow stack 70mg ghk-cu + bpc-157 + tb-500 glow 5:1:1 50/10/10 blend ghk bpc tb blend glow 70 glow 50 glow 70 5:1:1 blend glow-stack glow stack glowstack glow blend glow peptide ghk-cu + bpc-157 + tb-500 skin glow sting recovery copper uglies glow 50 glow 70 glow drip recovery skin/hair injury repair anti-aging discussion soft-tissue healing collagen discussion post-procedure aesthetic recovery wound/scar remodeling talk skin glow sting recovery copper uglies glow 50 glow 70 glow drip glow combines ghk-cu, bpc-157 and tb-500; people discuss the blend for skin appearance and injury recovery. users describe possible skin or recovery changes over weeks, but injection sting, nausea or dizziness can be more noticeable. ingredients, schedules and other treatments vary between blends. glow stack is a named blend for recovery. ghk-cu portion gets credit for tone, firmness, hydration feel, recovery look in photos \u2014 lighting and skincare confound heavily. the copper pin stings. talk in per-peptide mg, not one \u201ctotal mg.\u201d healing stacks (named blends) peptide mixed mixed \u2014 bpc may be near the complaint; tb and ghk are treated as whole-body. mixed local systemic", "legal_class": null }, { "id": 153, "slug": "klow-stack", "name": "KLOW stack", "aliases": [ "Klow blend", "KLOW peptide", "GLOW + KPV", "BPC TB GHK KPV", "klow 80mg", "BPC-157 TB-500 GHK-Cu KPV", "50/10/10/10 blend", "Hyper Recovery Stack (clinic nickname)", "CLO stack (misheard)", "KLOW 80", "5:1:1:1 blend" ], "type": "Peptide", "category": "Healing stacks (named blends)", "goals_use_cases": [ "recovery", "gut health", "inflammation discussion", "skin/hair", "injury repair", "soft-tissue healing", "post-procedure calm-down", "anti-aging / collagen talk", "systemic \u201cheal everything\u201d convenience stack" ], "delivery_methods": [ "subcutaneous", "pre-mixed multi-peptide vial" ], "discussion_popularity": "High", "reach": "Mixed", "misspellings_search_terms": [ "klow-stack", "klow stack", "klowstack", "Klow blend", "KLOW peptide", "GLOW + KPV", "gut", "inflammation", "klow", "skin", "copper uglies", "klow 80", "5:1:1:1" ], "feel_search": [ "gut", "inflammation", "klow", "skin", "copper uglies", "klow 80", "5:1:1:1" ], "summary": "KLOW is a four-peptide blend of GHK-Cu, BPC-157, TB-500 and KPV, discussed for skin, recovery and gut symptoms.", "search_blob": "klow stack klow-stack klow blend klow peptide glow + kpv bpc tb ghk kpv klow 80mg bpc-157 tb-500 ghk-cu kpv 50/10/10/10 blend hyper recovery stack (clinic nickname) clo stack (misheard) klow 80 5:1:1:1 blend klow-stack klow stack klowstack klow blend klow peptide glow + kpv gut inflammation klow skin copper uglies klow 80 5:1:1:1 recovery gut health inflammation discussion skin/hair injury repair soft-tissue healing post-procedure calm-down anti-aging / collagen talk systemic \u201cheal everything\u201d convenience stack gut inflammation klow skin copper uglies klow 80 5:1:1:1 klow is a four-peptide blend of ghk-cu, bpc-157, tb-500 and kpv, discussed for skin, recovery and gut symptoms. the reviewed reports range from extreme fatigue after two weeks to firmer-looking skin around week four. some favorable reports also involved collagen, topical skincare or a modified blend. klow stack is a named blend people look up for recovery. ghk-cu portion keeps the aesthetic pitch (tone, recovery look, ecm/collagen talk, some hair/scalp adjacency). four peptides in one pin. read each mg on the label. healing stacks (named blends) peptide mixed mixed \u2014 the blend is whole-body once injected; some still pin the bpc portion near a complaint. mixed local systemic", "legal_class": null }, { "id": 154, "slug": "slu-pp-915", "name": "SLU-PP-915", "aliases": [ "SLU PP 915", "SLUPP915", "915 ERR agonist", "oral ERR pan-agonist", "915", "SLU-PP 915", "SLU-PP915", "oral ERR pan-agonist (915)", "compound 10s (boronic acid pan-ERR)" ], "type": "Non-peptide", "category": "Metabolic research compounds", "goals_use_cases": [ "endurance discussion", "fat loss", "metabolic health", "exercise-mimetic research", "performance", "fat loss / body recomposition (discussed)", "performance / aerobic capacity (preclinical)", "mitochondrial / oxidative capacity (discussed)", "oral alternative to SLU-PP-332 (community)", "heart-failure / cardiac metabolic research (preclinical)" ], "delivery_methods": [ "oral", "research injection in animal work" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "slu-pp-915", "slu pp 915", "slupp915", "915", "SLU-PP 915", "SLU-PP915", "endurance", "cardio", "exercise mimetic", "zone 2", "pre-workout", "10mg", "COA", "fasted cardio" ], "feel_search": [ "endurance", "cardio", "915", "exercise mimetic", "zone 2", "pre-workout", "fasted cardio" ], "summary": "SLU-PP-915 is an experimental oral small molecule studied for endurance by activating estrogen-related receptors; it is chemically distinct from SLU-PP-332.", "search_blob": "slu-pp-915 slu-pp-915 slu pp 915 slupp915 915 err agonist oral err pan-agonist 915 slu-pp 915 slu-pp915 oral err pan-agonist (915) compound 10s (boronic acid pan-err) slu-pp-915 slu pp 915 slupp915 915 slu-pp 915 slu-pp915 endurance cardio exercise mimetic zone 2 pre-workout 10mg coa fasted cardio endurance discussion fat loss metabolic health exercise-mimetic research performance fat loss / body recomposition (discussed) performance / aerobic capacity (preclinical) mitochondrial / oxidative capacity (discussed) oral alternative to slu-pp-332 (community) heart-failure / cardiac metabolic research (preclinical) endurance cardio 915 exercise mimetic zone 2 pre-workout fasted cardio slu-pp-915 is an experimental oral small molecule studied for endurance by activating estrogen-related receptors; it is chemically distinct from slu-pp-332. some posters describe easier training and focus, but also daytime fatigue, slower recovery and tendon discomfort. slu-pp-915 is an oral compound people look up for endurance. zone-2 stamina and cut-phase oxidation chatter. some people say 2 mg is already high; others want 20\u2013100 mg. 2026 x polls split 1 mg vs 10 mg vs 20 mg. no consensus. metabolic research compounds non-peptide systemic systemic \u2014 pan-err small molecule (err\u03b1/\u03b2/\u03b3) aimed at aerobic/exercise-mimetic gene programs in muscle, heart, and other high-energy tissues. systemic whole-body circulating", "legal_class": null }, { "id": 155, "slug": "hgh-somatropin", "name": "HGH (Somatropin)", "aliases": [ "Human Growth Hormone", "somatropin", "GH", "rhGH" ], "type": "Peptide", "category": "Growth hormone axis", "goals_use_cases": [ "muscle growth", "fat loss", "recovery", "longevity" ], "delivery_methods": [ "subcutaneous", "intramuscular" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "hgh-somatropin", "hgh somatropin", "hghsomatropin", "HGH (Somatropin)", "hgh-(somatropin)", "Human Growth Hormone", "hgh", "somatropin", "water retention", "carpal", "191aa", "kits", "IGF-1", "split dose", "empty stomach" ], "feel_search": [ "hgh", "somatropin", "water retention", "carpal", "191aa", "kits", "IGF-1", "split dose", "empty stomach" ], "summary": "Somatropin is recombinant human growth hormone\u2014the same molecule covered under HGH, discussed for replacement therapy, recovery and physique changes.", "search_blob": "hgh (somatropin) hgh-somatropin human growth hormone somatropin gh rhgh hgh-somatropin hgh somatropin hghsomatropin hgh (somatropin) hgh-(somatropin) human growth hormone hgh somatropin water retention carpal 191aa kits igf-1 split dose empty stomach muscle growth fat loss recovery longevity hgh somatropin water retention carpal 191aa kits igf-1 split dose empty stomach somatropin is recombinant human growth hormone\u2014the same molecule covered under hgh, discussed for replacement therapy, recovery and physique changes. some notice little immediately; others report puffiness, tight rings, hand tingling, fatigue or sleep changes. appearance and recovery claims are usually assessed over longer periods. hgh (somatropin) is a peptide people look up for muscle. hgh (somatropin) is discussed for recomp, strength continuity, or soft-tissue recovery depending on class. gray-market iu claims are unreliable. legal status is part of the card. growth hormone axis peptide systemic systemic gh replacement / abuse context. systemic whole-body circulating", "legal_class": null }, { "id": 156, "slug": "hgh-fragment-176-191", "name": "HGH Fragment 176-191", "aliases": [ "Frag 176-191", "HGH Frag", "fragment 176", "Fragment 176-191", "hGH Frag", "HGH Fragment 176-191", "frag-176-191", "hGH Fragment 176-191", "GH Frag 176-191", "hGH 176-191", "Growth hormone fragment 176-191", "C-terminal hGH fragment (community label)", "hGH frag 176\u2013191", "HGH Frag 176-191" ], "type": "Peptide", "category": "Metabolic / fat-loss peptides", "goals_use_cases": [ "fat loss", "performance", "recovery" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "hgh-fragment-176-191", "hgh fragment 176 191", "hghfragment176191", "HGH Fragment 176-191", "Frag 176-191", "HGH Frag", "frag 176 191", "frag176191", "fat loss", "fasted", "cut", "fragment" ], "feel_search": [ "fat loss", "fasted", "cut", "fragment" ], "summary": "HGH fragment 176\u2013191 is a short growth-hormone fragment marketed for fat loss; it is not full-length HGH or automatically interchangeable with AOD-9604.", "search_blob": "hgh fragment 176-191 hgh-fragment-176-191 frag 176-191 hgh frag fragment 176 fragment 176-191 hgh frag hgh fragment 176-191 frag-176-191 hgh fragment 176-191 gh frag 176-191 hgh 176-191 growth hormone fragment 176-191 c-terminal hgh fragment (community label) hgh frag 176\u2013191 hgh frag 176-191 hgh-fragment-176-191 hgh fragment 176 191 hghfragment176191 hgh fragment 176-191 frag 176-191 hgh frag frag 176 191 frag176191 fat loss fasted cut fragment fat loss performance recovery fat loss fasted cut fragment hgh fragment 176\u2013191 is a short growth-hormone fragment marketed for fat loss; it is not full-length hgh or automatically interchangeable with aod-9604. there is no clear immediate sensation in the reviewed report. its fat-loss claim involved fasting and cardio, so it does not show what the fragment contributed. hgh fragment 176-191 is a peptide people look up for fat loss. community fat-loss talk; human evidence weaker than marketing. fasted am and/or pre-bed pins dominate. often lumped with aod-9604. metabolic / fat-loss peptides peptide systemic systemic fat-loss fragment peptide lore. systemic whole-body circulating", "legal_class": null }, { "id": 157, "slug": "liraglutide", "name": "Liraglutide", "aliases": [ "Victoza", "Saxenda", "lira" ], "type": "Peptide", "category": "Metabolic / GLP-1 class", "goals_use_cases": [ "fat loss", "appetite suppression", "insulin sensitivity", "cardiovascular" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "liraglutide", "Victoza", "Saxenda", "lira", "liraglutide peptide", "liraglutide dosage", "fat loss", "appetite suppression", "insulin sensitivity", "cardiovascular" ], "feel_search": [ "fat loss", "appetite suppression", "insulin sensitivity", "cardiovascular" ], "summary": "Liraglutide is a once-daily injectable GLP-1 receptor agonist used in diabetes and weight management, sold under brands including Victoza and Saxenda.", "search_blob": "liraglutide liraglutide victoza saxenda lira liraglutide victoza saxenda lira liraglutide peptide liraglutide dosage fat loss appetite suppression insulin sensitivity cardiovascular fat loss appetite suppression insulin sensitivity cardiovascular fat loss appetite suppression insulin sensitivity cardiovascular liraglutide is a once-daily injectable glp-1 receptor agonist used in diabetes and weight management, sold under brands including victoza and saxenda. appetite can change early, but nausea and sleep disruption may dominate. in the reviewed timing thread, some preferred evenings while one switched to mornings because insomnia outweighed the nausea. liraglutide is a daily medicine people look up for appetite. appetite quieting and gradual weight change commonly reported as dose escalates. metabolic / glp-1 class peptide systemic systemic \u2014 whole-body glp-1 effects on appetite, gastric emptying, and glycemic control. systemic whole-body circulating", "legal_class": null }, { "id": 158, "slug": "mgf-peg-mgf", "name": "MGF / PEG-MGF", "aliases": [ "Mechano Growth Factor", "PEGylated MGF", "IGF-1Ec" ], "type": "Peptide", "category": "Growth factors / muscle", "goals_use_cases": [ "muscle growth", "recovery", "injury repair" ], "delivery_methods": [ "intramuscular", "subcutaneous" ], "discussion_popularity": "Medium", "reach": "Mixed", "misspellings_search_terms": [ "mgf-peg-mgf", "mgf peg mgf", "mgfpegmgf", "MGF / PEG-MGF", "mgf-/-peg-mgf", "Mechano Growth Factor", "muscle growth", "recovery", "injury repair" ], "feel_search": [ "muscle growth", "recovery", "injury repair" ], "summary": "MGF/PEG-MGF is an umbrella for synthetic IGF-1 E-domain peptides sold for local muscle recovery; PEG modification changes the product.", "search_blob": "mgf / peg-mgf mgf-peg-mgf mechano growth factor pegylated mgf igf-1ec mgf-peg-mgf mgf peg mgf mgfpegmgf mgf / peg-mgf mgf-/-peg-mgf mechano growth factor muscle growth recovery injury repair muscle growth recovery injury repair muscle growth recovery injury repair mgf/peg-mgf is an umbrella for synthetic igf-1 e-domain peptides sold for local muscle recovery; peg modification changes the product. reports range from immediate fullness to injection pain or no noticeable effect. older stacked logs cannot isolate mgf from peg-mgf or accompanying igf. mgf / peg-mgf is a peptide people look up for muscle. mgf / peg-mgf is discussed for recomp, strength continuity, or soft-tissue recovery depending on class. growth factors / muscle peptide mixed mixed \u2014 local/systemic igf-splice variant research chem culture. mixed local systemic", "legal_class": null }, { "id": 159, "slug": "dasatinib-quercetin", "name": "Dasatinib + Quercetin", "aliases": [ "D+Q", "D plus Q senolytic", "Sprycel + quercetin" ], "type": "Non-peptide", "category": "Longevity & cellular energy", "goals_use_cases": [ "longevity", "recovery", "bone health", "cognition" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "dasatinib-quercetin", "dasatinib quercetin", "dasatinibquercetin", "Dasatinib + Quercetin", "dasatinib-+-quercetin", "D+Q", "longevity", "recovery", "bone health", "cognition" ], "feel_search": [ "longevity", "recovery", "bone health", "cognition" ], "summary": "D+Q combines the leukemia drug dasatinib with the flavonoid quercetin in experimental research targeting senescent cells.", "search_blob": "dasatinib + quercetin dasatinib-quercetin d+q d plus q senolytic sprycel + quercetin dasatinib-quercetin dasatinib quercetin dasatinibquercetin dasatinib + quercetin dasatinib-+-quercetin d+q longevity recovery bone health cognition longevity recovery bone health cognition longevity recovery bone health cognition d+q combines the leukemia drug dasatinib with the flavonoid quercetin in experimental research targeting senescent cells. one long-term user reports no noticeable effect; another credits a rapamycin/d+q stack with better joints and activity. neither observation isolates the combination\u2019s mechanism. dasatinib + quercetin is an oral compound people look up for longevity. intermittent dosing papers popular in longevity circles. longevity & cellular energy non-peptide systemic systemic intermittent senolytic drug+polyphenol combo. systemic whole-body circulating", "legal_class": null }, { "id": 160, "slug": "glynac", "name": "GlyNAC", "aliases": [ "Glycine + NAC", "glycine N-acetylcysteine" ], "type": "Non-peptide", "category": "Longevity & cellular energy", "goals_use_cases": [ "longevity", "energy", "recovery" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "glynac", "Glycine + NAC", "glycine N-acetylcysteine", "glynac peptide", "glynac dosage", "GlyNAC dose", "longevity", "energy", "recovery" ], "feel_search": [ "longevity", "energy", "recovery" ], "summary": "GlyNAC is the combination of glycine and N-acetylcysteine, discussed for glutathione support, aging-related health and recovery.", "search_blob": "glynac glynac glycine + nac glycine n-acetylcysteine glynac glycine + nac glycine n-acetylcysteine glynac peptide glynac dosage glynac dose longevity energy recovery longevity energy recovery longevity energy recovery glynac is the combination of glycine and n-acetylcysteine, discussed for glutathione support, aging-related health and recovery. responses range from gi discomfort or lightheadedness to better or worse sleep. the first-night reports conflict, so neither component nor an ideal time of day can be inferred from them. glynac is an oral compound people look up for longevity. glynac is discussed for aging markers, energy, or recovery more than acute gym pumps. two common supplements co-taken. longevity & cellular energy non-peptide systemic systemic oral gsh precursor combination. systemic whole-body circulating", "legal_class": null }, { "id": 161, "slug": "akg", "name": "Alpha-Ketoglutarate (AKG)", "aliases": [ "Ca-AKG", "calcium alpha-ketoglutarate" ], "type": "Non-peptide", "category": "Longevity & cellular energy", "goals_use_cases": [ "longevity", "recovery", "bone health" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "akg", "Alpha-Ketoglutarate (AKG)", "alpha-ketoglutarate-(akg)", "Ca-AKG", "calcium alpha-ketoglutarate", "akg peptide", "longevity", "recovery", "bone health" ], "feel_search": [ "longevity", "recovery", "bone health" ], "summary": "Alpha-ketoglutarate (AKG) is a normal energy-metabolism compound sold in several supplement forms for longevity and exercise interest.", "search_blob": "alpha-ketoglutarate (akg) akg ca-akg calcium alpha-ketoglutarate akg alpha-ketoglutarate (akg) alpha-ketoglutarate-(akg) ca-akg calcium alpha-ketoglutarate akg peptide longevity recovery bone health longevity recovery bone health longevity recovery bone health alpha-ketoglutarate (akg) is a normal energy-metabolism compound sold in several supplement forms for longevity and exercise interest. reports range from subtle running benefits to no observable change over months or years. different akg salts and supplement stacks complicate comparisons. akg is an oral compound people look up for energy. actual accounts range from subtle exercise benefits with continued stacked use to no observable effect over months or years. longevity & cellular energy non-peptide systemic systemic metabolic intermediate supplement. systemic whole-body circulating", "legal_class": null }, { "id": 162, "slug": "acarbose", "name": "Acarbose", "aliases": [ "Precose", "Glucobay" ], "type": "Non-peptide", "category": "Longevity & cellular energy", "goals_use_cases": [ "longevity", "insulin sensitivity" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Mixed", "misspellings_search_terms": [ "acarbose", "Precose", "Glucobay", "acarbose peptide", "acarbose dosage", "Acarbose dose", "longevity", "insulin sensitivity" ], "feel_search": [ "longevity", "insulin sensitivity" ], "summary": "Acarbose is a tablet that slows carbohydrate digestion to reduce after-meal glucose rises; biohackers also discuss it for longevity.", "search_blob": "acarbose acarbose precose glucobay acarbose precose glucobay acarbose peptide acarbose dosage acarbose dose longevity insulin sensitivity longevity insulin sensitivity longevity insulin sensitivity acarbose is a tablet that slows carbohydrate digestion to reduce after-meal glucose rises; biohackers also discuss it for longevity. gas and bloating may be more noticeable than glucose changes. in one log, some meals felt uneventful while a ramen-and-vegetable meal brought hours of gas. acarbose is an oral tablet people look up for glucose. blunts postprandial glucose spikes by delaying complex carb breakdown. longevity & cellular energy non-peptide mixed mixed \u2014 primarily gut-local enzyme block with systemic glucose effects. mixed local systemic", "legal_class": null }, { "id": 163, "slug": "selegiline", "name": "Selegiline (Deprenyl)", "aliases": [ "Deprenyl", "Eldepryl", "Emsam", "l-deprenyl" ], "type": "Non-peptide", "category": "Longevity & cellular energy", "goals_use_cases": [ "longevity", "mood", "cognition" ], "delivery_methods": [ "oral", "sublingual" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "selegiline", "Selegiline (Deprenyl)", "selegiline-(deprenyl)", "Deprenyl", "Eldepryl", "Emsam", "longevity", "mood", "cognition" ], "feel_search": [ "longevity", "mood", "cognition" ], "summary": "Selegiline, or deprenyl, is a monoamine oxidase inhibitor used in Parkinson's treatment and discussed in nootropic and longevity circles.", "search_blob": "selegiline (deprenyl) selegiline deprenyl eldepryl emsam l-deprenyl selegiline selegiline (deprenyl) selegiline-(deprenyl) deprenyl eldepryl emsam longevity mood cognition longevity mood cognition longevity mood cognition selegiline, or deprenyl, is a monoamine oxidase inhibitor used in parkinson's treatment and discussed in nootropic and longevity circles. one commenter described a subtle mental lift that faded with repeated use; another described difficult symptoms after missed doses and stopping. selegiline (deprenyl) is an oral compound people look up for longevity. mood/motivation anecdotes at various doses \u2014 medical interactions matter. longevity & cellular energy non-peptide systemic systemic mao-b inhibitor drug. systemic whole-body circulating", "legal_class": null }, { "id": 164, "slug": "low-dose-naltrexone", "name": "Low-Dose Naltrexone", "aliases": [ "LDN", "naltrexone low dose" ], "type": "Non-peptide", "category": "Immune / antimicrobial", "goals_use_cases": [ "recovery", "immune", "mood", "gut health" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "low-dose-naltrexone", "low dose naltrexone", "lowdosenaltrexone", "Low-Dose Naltrexone", "LDN", "naltrexone low dose", "recovery", "immune", "mood", "gut health" ], "feel_search": [ "recovery", "immune", "mood", "gut health" ], "summary": "Low-dose naltrexone (LDN) is an opioid-receptor-blocking medicine used off label for conditions such as chronic pain; it is the same substance as the LDN entry.", "search_blob": "low-dose naltrexone low-dose-naltrexone ldn naltrexone low dose low-dose-naltrexone low dose naltrexone lowdosenaltrexone low-dose naltrexone ldn naltrexone low dose recovery immune mood gut health recovery immune mood gut health recovery immune mood gut health low-dose naltrexone (ldn) is an opioid-receptor-blocking medicine used off label for conditions such as chronic pain; it is the same substance as the ldn entry. early grogginess, gi discomfort and sleep changes vary widely. some report encouraging days, but a detailed longer diary ended with no net benefit after months. low-dose naltrexone is an oral compound people look up for recovery. discussed for immune modulation, pain, and autoimmune lore \u2014 distinct from full-dose addiction dosing. immune / antimicrobial non-peptide systemic systemic low-dose opioid antagonist immunomodulation lore. systemic whole-body circulating", "legal_class": null }, { "id": 165, "slug": "yk-11", "name": "YK-11", "aliases": [ "YK11", "myostatin SARM", "myostatin-related SARM discussion", "YK-11", "ykl-11", "YK 11", "Myostine (research-commerce / Health Canada nickname)", "Myobol (forum/vendor nickname)", "(17\u03b1,20E)-17,20-[(1-methoxyethylidene)bis(oxy)]-3-oxo-19-norpregna-4,20-diene-21-carboxylic acid methyl ester" ], "type": "Non-peptide", "category": "Performance / endurance", "goals_use_cases": [ "muscle growth", "performance" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "yk-11", "yk 11", "yk11", "myostatin SARM", "yk-11 peptide", "yk-11 dosage", "ykl 11", "ykl11", "YK-11", "YK11", "YK 11", "muscle growth", "performance" ], "feel_search": [ "muscle growth", "performance" ], "summary": "YK-11 is a steroidal SARM-like research compound discussed for muscle and myostatin-related effects.", "search_blob": "yk-11 yk-11 yk11 myostatin sarm myostatin-related sarm discussion yk-11 ykl-11 yk 11 myostine (research-commerce / health canada nickname) myobol (forum/vendor nickname) (17\u03b1,20e)-17,20-[(1-methoxyethylidene)bis(oxy)]-3-oxo-19-norpregna-4,20-diene-21-carboxylic acid methyl ester yk-11 yk 11 yk11 myostatin sarm yk-11 peptide yk-11 dosage ykl 11 ykl11 yk-11 yk11 yk 11 muscle growth performance muscle growth performance muscle growth performance yk-11 is a steroidal sarm-like research compound discussed for muscle and myostatin-related effects. one user reported size and strength gains alongside joint pain, acne, hair loss and lower libido; returning to training confounded the gains. yk-11 is an oral compound people look up for muscle. anecdotes of lean mass and hardness; confounded by training/diet/other agents. human rcts are not the foundation \u2014 mostly community + limited preclinical framing. performance / endurance non-peptide systemic systemic myostatin-pathway research chem. systemic whole-body circulating", "legal_class": null }, { "id": 166, "slug": "s-4-andarine", "name": "S-4 (Andarine)", "aliases": [ "Andarine", "S4", "GTx-007" ], "type": "Non-peptide", "category": "Performance / endurance", "goals_use_cases": [ "fat loss", "muscle growth", "performance" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "s-4-andarine", "s 4 andarine", "s4andarine", "S-4 (Andarine)", "s-4-(andarine)", "Andarine", "fat loss", "muscle growth", "performance" ], "feel_search": [ "fat loss", "muscle growth", "performance" ], "summary": "Andarine (S-4) is a research SARM discussed for cutting and muscle retention, with distinctive visual-disturbance reports.", "search_blob": "s-4 (andarine) s-4-andarine andarine s4 gtx-007 s-4-andarine s 4 andarine s4andarine s-4 (andarine) s-4-(andarine) andarine fat loss muscle growth performance fat loss muscle growth performance fat loss muscle growth performance andarine (s-4) is a research sarm discussed for cutting and muscle retention, with distinctive visual-disturbance reports. one user described intermittent yellowish vision that persisted on missed-dose days; they were also taking sr9009. andarine is an oral sarm people look up for muscle. s-4 (andarine) is discussed for recomp, strength continuity, or soft-tissue recovery depending on class. performance / endurance non-peptide systemic systemic sarm research chem. systemic whole-body circulating", "legal_class": null }, { "id": 167, "slug": "s-23", "name": "S-23", "aliases": [ "S23", "S 23", "S23 SARM", "S-23", "s23", "S-23 SARM", "Mastorin (informal / research-chem trade discussion)", "Ultrabolic (branded research-chem label discussed in forums)", "(S)-N-(4-cyano-3-trifluoromethylphenyl)-3-(3-fluoro-4-chlorophenoxy)-2-hydroxy-2-methylpropanamide" ], "type": "Non-peptide", "category": "Performance / endurance", "goals_use_cases": [ "muscle growth", "fat loss", "performance" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "s-23", "s 23", "s-23 peptide", "s-23 dosage", "S-23 dose", "S-23", "S-23 SARM", "S23 SARM", "S 23", "Mastorin (informal / research-chem trade discussion)", "muscle growth", "fat loss", "performance" ], "feel_search": [ "muscle growth", "fat loss", "performance" ], "summary": "S-23 is a nonsteroidal research SARM discussed for muscle and body recomposition, with substantial hormone-suppression concerns.", "search_blob": "s-23 s-23 s23 s 23 s23 sarm s-23 s23 s-23 sarm mastorin (informal / research-chem trade discussion) ultrabolic (branded research-chem label discussed in forums) (s)-n-(4-cyano-3-trifluoromethylphenyl)-3-(3-fluoro-4-chlorophenoxy)-2-hydroxy-2-methylpropanamide s-23 s 23 s-23 peptide s-23 dosage s-23 dose s-23 s-23 sarm s23 sarm s 23 mastorin (informal / research-chem trade discussion) muscle growth fat loss performance muscle growth fat loss performance muscle growth fat loss performance s-23 is a nonsteroidal research sarm discussed for muscle and body recomposition, with substantial hormone-suppression concerns. one stacked-cycle user described stronger training drive, aggression and libido, but an unpleasant period after stopping. s-23 is an oral compound people look up for muscle. strength and lean look anecdotes; confounded. performance / endurance non-peptide systemic systemic sarm research chem. systemic whole-body circulating", "legal_class": null }, { "id": 168, "slug": "aicar", "name": "AICAR", "aliases": [ "AICA ribonucleotide", "Acadesine", "5-aminoimidazole-4-carboxamide riboside" ], "type": "Non-peptide", "category": "Performance / endurance", "goals_use_cases": [ "performance", "fat loss", "insulin sensitivity" ], "delivery_methods": [ "subcutaneous", "intramuscular" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "aicar", "AICA ribonucleotide", "Acadesine", "5-aminoimidazole-4-carboxamide riboside", "aicar peptide", "aicar dosage", "performance", "fat loss", "insulin sensitivity" ], "feel_search": [ "performance", "fat loss", "insulin sensitivity" ], "summary": "AICAR (acadesine) is a non-peptide nucleoside studied for metabolic signaling and discussed as an endurance aid.", "search_blob": "aicar aicar aica ribonucleotide acadesine 5-aminoimidazole-4-carboxamide riboside aicar aica ribonucleotide acadesine 5-aminoimidazole-4-carboxamide riboside aicar peptide aicar dosage performance fat loss insulin sensitivity performance fat loss insulin sensitivity performance fat loss insulin sensitivity aicar (acadesine) is a non-peptide nucleoside studied for metabolic signaling and discussed as an endurance aid. the inspected stacked-use log reports little overall difference and credits its speedy, hot feeling to helios. it does not isolate aicar's effects. aicar is a non-peptide compound people look up for fat loss. poor oral practicality and research-chem reality dominate honest discussion. poor oral practicality and research-chem reality dominate honest discussion. performance / endurance non-peptide systemic systemic ampk research tool. systemic whole-body circulating", "legal_class": null }, { "id": 169, "slug": "bimagrumab", "name": "Bimagrumab", "aliases": [ "BYM338", "bima" ], "type": "Peptide", "category": "Growth factors / muscle", "goals_use_cases": [ "muscle growth", "fat loss" ], "delivery_methods": [ "IV", "subcutaneous" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "bimagrumab", "BYM338", "bima", "bimagrumab peptide", "bimagrumab dosage", "Bimagrumab dose", "muscle growth", "fat loss" ], "feel_search": [ "muscle growth", "fat loss" ], "summary": "Bimagrumab is an investigational activin-receptor antibody studied for muscle mass and metabolic outcomes.", "search_blob": "bimagrumab bimagrumab bym338 bima bimagrumab bym338 bima bimagrumab peptide bimagrumab dosage bimagrumab dose muscle growth fat loss muscle growth fat loss muscle growth fat loss bimagrumab is an investigational activin-receptor antibody studied for muscle mass and metabolic outcomes. the inspected forum thread asks about access and trial experience. no commenter supplies a firsthand treatment response or day-to-day timeline. bimagrumab is an investigational antibody people look up for muscle. trials reported increases in lean mass. growth factors / muscle peptide systemic systemic antibody against activin receptor pathway. systemic whole-body circulating", "legal_class": null }, { "id": 170, "slug": "ace-031", "name": "ACE-031", "aliases": [ "ActRIIB-Fc", "ACE031", "Ramatercept (related)" ], "type": "Peptide", "category": "Growth factors / muscle", "goals_use_cases": [ "muscle growth", "performance", "bone health" ], "delivery_methods": [ "subcutaneous", "intramuscular" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "ace-031", "ace 031", "ace031", "ActRIIB-Fc", "Ramatercept (related)", "ace-031 peptide", "muscle growth", "performance", "bone health" ], "feel_search": [ "muscle growth", "performance", "bone health" ], "summary": "ACE-031 is a soluble activin-receptor decoy studied for muscle growth; its clinical development stopped after safety concerns.", "search_blob": "ace-031 ace-031 actriib-fc ace031 ramatercept (related) ace-031 ace 031 ace031 actriib-fc ramatercept (related) ace-031 peptide muscle growth performance bone health muscle growth performance bone health muscle growth performance bone health ace-031 is a soluble activin-receptor decoy studied for muscle growth; its clinical development stopped after safety concerns. an early forum account describes more sweating and a stronger pump without added strength. product identity and other compounds limit what that shows. ace-031 is a peptide people look up for muscle. stronger pumps and sweating without strength gains; another heavily stacked account claims strength/size change within a week. growth factors / muscle peptide systemic systemic activin-pathway biologic (discontinued development). systemic whole-body circulating", "legal_class": null }, { "id": 171, "slug": "b7-33", "name": "B7-33", "aliases": [ "B7-33 relaxin analog", "H2 relaxin derivative" ], "type": "Peptide", "category": "Healing & repair", "goals_use_cases": [ "anti fibrotic", "cardiovascular", "recovery" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "b7-33", "b7 33", "b733", "B7-33 relaxin analog", "H2 relaxin derivative", "b7-33 peptide", "anti fibrotic", "cardiovascular", "recovery" ], "feel_search": [ "anti fibrotic", "cardiovascular", "recovery" ], "summary": "B7-33 is a synthetic relaxin-family peptide studied for signals involved in tissue scarring; it is not an organ-specific peptide extract.", "search_blob": "b7-33 b7-33 b7-33 relaxin analog h2 relaxin derivative b7-33 b7 33 b733 b7-33 relaxin analog h2 relaxin derivative b7-33 peptide anti fibrotic cardiovascular recovery anti fibrotic cardiovascular recovery anti fibrotic cardiovascular recovery b7-33 is a synthetic relaxin-family peptide studied for signals involved in tissue scarring; it is not an organ-specific peptide extract. a user combining b7-33 with bpc/tb reports early body sensations and easier exercise. their explanation of clearing tissue is unverified. b7-33 is a peptide people look up for recovery. studied for rxfp1 signaling and antifibrotic effects in preclinical settings. healing & repair peptide systemic systemic research peptide \u2014 relaxin-family/rxfp1 signaling, not an organ bioregulator or a proven local scar treatment. systemic whole-body circulating", "legal_class": null }, { "id": 172, "slug": "thymulin", "name": "Thymulin", "aliases": [ "thymic factor", "FTS-Zn", "facteur thymique s\u00e9rique" ], "type": "Peptide", "category": "Immune / antimicrobial", "goals_use_cases": [ "immune", "recovery", "longevity" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "thymulin", "thymic factor", "FTS-Zn", "facteur thymique s\u00e9rique", "thymulin peptide", "thymulin dosage", "immune", "recovery", "longevity" ], "feel_search": [ "immune", "recovery", "longevity" ], "summary": "Thymulin is a nine-amino-acid thymus hormone that depends on zinc, discussed for immune regulation; it differs from the multi-peptide extract Thymalin.", "search_blob": "thymulin thymulin thymic factor fts-zn facteur thymique s\u00e9rique thymulin thymic factor fts-zn facteur thymique s\u00e9rique thymulin peptide thymulin dosage immune recovery longevity immune recovery longevity immune recovery longevity thymulin is a nine-amino-acid thymus hormone that depends on zinc, discussed for immune regulation; it differs from the multi-peptide extract thymalin. one multi-peptide user initially credited symptom relief, then reported gut problems and withdrew confidence that the peptides had helped. thymulin is a peptide people look up for immune support. frame benefits around thymic hormone axis function and \u201cnormalization\u201d language. immune / antimicrobial peptide systemic systemic thymic-hormone discussion around a defined zinc-dependent nonapeptide; product naming is unusually error-prone. systemic whole-body circulating", "legal_class": null }, { "id": 173, "slug": "endoluten", "name": "Endoluten", "aliases": [ "Endoluten pineal bioregulator", "pineal gland peptide complex" ], "type": "Peptide", "category": "Organ bioregulators", "goals_use_cases": [ "sleep", "longevity", "hormone support" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "endoluten", "Endoluten pineal bioregulator", "pineal gland peptide complex", "endoluten peptide", "endoluten dosage", "Endoluten dose", "sleep", "longevity", "hormone support" ], "feel_search": [ "sleep", "longevity", "hormone support" ], "summary": "Endoluten is an oral peptide complex from young-animal pineal tissue, marketed as a bioregulator for sleep and longevity.", "search_blob": "endoluten endoluten endoluten pineal bioregulator pineal gland peptide complex endoluten endoluten pineal bioregulator pineal gland peptide complex endoluten peptide endoluten dosage endoluten dose sleep longevity hormone support sleep longevity hormone support sleep longevity hormone support endoluten is an oral peptide complex from young-animal pineal tissue, marketed as a bioregulator for sleep and longevity. a ten-day diary describes sleepiness, calm and less mental chatter, but reduced sexual arousal and no lucid dream by day ten. endoluten is a peptide people look up for sleep. benefits, when claimed, are usually mild (comfort, \u201csupport,\u201d recovery feel) and hard to separate from sleep/diet. organ bioregulators peptide systemic oral animal-pineal peptide complex marketed as a pineal bioregulator; systemic benefit, composition equivalence, and human efficacy remain uncertain. systemic whole-body circulating", "legal_class": null }, { "id": 174, "slug": "pancragen", "name": "Pancragen", "aliases": [ "Pancragen peptide", "pancreas bioregulator", "KEDW tetrapeptide" ], "type": "Peptide", "category": "Organ bioregulators", "goals_use_cases": [ "insulin sensitivity", "longevity", "energy", "hormone support" ], "delivery_methods": [ "subcutaneous", "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "pancragen", "Pancragen peptide", "pancreas bioregulator", "KEDW tetrapeptide", "pancragen dosage", "Pancragen dose", "insulin sensitivity", "longevity", "energy", "hormone support" ], "feel_search": [ "insulin sensitivity", "longevity", "energy", "hormone support" ], "summary": "Pancragen is a short synthetic peptide sold as a pancreas bioregulator for metabolic support; brand extracts may contain different material.", "search_blob": "pancragen pancragen pancragen peptide pancreas bioregulator kedw tetrapeptide pancragen pancragen peptide pancreas bioregulator kedw tetrapeptide pancragen dosage pancragen dose insulin sensitivity longevity energy hormone support insulin sensitivity longevity energy hormone support insulin sensitivity longevity energy hormone support pancragen is a short synthetic peptide sold as a pancreas bioregulator for metabolic support; brand extracts may contain different material. there is too little detailed reporting to describe a typical feel. one user perceived better glucose after a week but supplied no readings, route or later follow-up. pancragen is a peptide people look up for longevity. site reactions (if injected) or gi/mood shifts (if oral) often dominate before benefits. organ bioregulators peptide systemic aimed at one organ in the writeups, but people still take it as a whole-body capsule or pin. systemic whole-body circulating", "legal_class": null }, { "id": 175, "slug": "thyreogen", "name": "Thyreogen", "aliases": [ "Thyreogen peptide", "thyroid bioregulator" ], "type": "Peptide", "category": "Organ bioregulators", "goals_use_cases": [ "hormone support", "energy", "longevity" ], "delivery_methods": [ "oral", "subcutaneous" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "thyreogen", "Thyreogen peptide", "thyroid bioregulator", "thyreogen dosage", "Thyreogen dose", "thyreogen research", "hormone support", "energy", "longevity" ], "feel_search": [ "hormone support", "energy", "longevity" ], "summary": "Thyreogen (A-2) is a thyroid-tissue-derived mixture of peptide fractions marketed for thyroid support.", "search_blob": "thyreogen thyreogen thyreogen peptide thyroid bioregulator thyreogen thyreogen peptide thyroid bioregulator thyreogen dosage thyreogen dose thyreogen research hormone support energy longevity hormone support energy longevity hormone support energy longevity thyreogen (a-2) is a thyroid-tissue-derived mixture of peptide fractions marketed for thyroid support. one capsule user noticed no benefit; another described better energy while also using thyroid replacement and several other interventions. thyreogen is an oral peptide people look up for thyroid. community and regional literature frame benefits around thyroid function and \u201cnormalization\u201d language. organ bioregulators peptide systemic oral thyroid-tissue peptide mixture marketed for thyroid support; organ-focused claims remain vendor-led. systemic whole-body circulating", "legal_class": null }, { "id": 176, "slug": "cortexin", "name": "Cortexin", "aliases": [ "Cortexin lyophilisate", "cattle-brain polypeptides" ], "type": "Peptide", "category": "Cognitive / nootropic peptides", "goals_use_cases": [ "cognition", "memory", "focus", "mood" ], "delivery_methods": [ "intramuscular" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "cortexin", "Cortexin lyophilisate", "cattle-brain polypeptides", "cortexin peptide", "cortexin dosage", "Cortexin dose", "cognition", "memory", "focus", "mood" ], "feel_search": [ "cognition", "memory", "focus", "mood" ], "summary": "Cortexin is an animal-brain-derived mixture of peptide fractions supplied for intramuscular injection, distinct from the single peptide Cortagen.", "search_blob": "cortexin cortexin cortexin lyophilisate cattle-brain polypeptides cortexin cortexin lyophilisate cattle-brain polypeptides cortexin peptide cortexin dosage cortexin dose cognition memory focus mood cognition memory focus mood cognition memory focus mood cortexin is an animal-brain-derived mixture of peptide fractions supplied for intramuscular injection, distinct from the single peptide cortagen. one user reports better everyday short-term memory after a course; another describes alertness and work recall building across repeated injections. cortexin is a peptide people look up for cognition. inspected users described changes across several injections, with wide disagreement about persistence. cognitive / nootropic peptides peptide systemic systemic im brain-cortex polypeptide mixture; organ-framed, but not a single peptide or an oral capsule product. systemic whole-body circulating", "legal_class": null }, { "id": 177, "slug": "adamax", "name": "Adamax", "aliases": [ "Adamax peptide", "Semax analog adamantane" ], "type": "Peptide", "category": "Cognitive / nootropic peptides", "goals_use_cases": [ "cognition", "focus", "energy" ], "delivery_methods": [ "nasal", "subcutaneous" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "adamax", "Adamax peptide", "Semax analog adamantane", "adamax dosage", "Adamax dose", "adamax research", "cognition", "focus", "energy" ], "feel_search": [ "cognition", "focus", "energy" ], "summary": "Adamax is an adamantane-modified Semax-family research peptide discussed as a nootropic for focus and memory.", "search_blob": "adamax adamax adamax peptide semax analog adamantane adamax adamax peptide semax analog adamantane adamax dosage adamax dose adamax research cognition focus energy cognition focus energy cognition focus energy adamax is an adamantane-modified semax-family research peptide discussed as a nootropic for focus and memory. a nasal-use account describes clarity within hours and better study recall after a week, alongside headaches and harder sleep. the author also used selank. adamax is a peptide people look up for focus. some describe a clean focus shift like semax-class sprays; others feel little acutely. community charts cluster around hundreds of mcg/day (nasal or sc), not multi-mg bodybuilding pins \u2014 see dose section. cognitive / nootropic peptides peptide systemic systemic/cns-oriented nootropic peptide analog discussion. systemic whole-body circulating", "legal_class": null }, { "id": 178, "slug": "colivelin", "name": "Colivelin", "aliases": [ "CLN", "ADNF-derived peptide", "colivelin peptide" ], "type": "Peptide", "category": "Cognitive / nootropic peptides", "goals_use_cases": [ "cognition", "memory" ], "delivery_methods": [ "subcutaneous", "nasal" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "colivelin", "CLN", "ADNF-derived peptide", "colivelin peptide", "colivelin dosage", "Colivelin dose", "cognition", "memory" ], "feel_search": [ "cognition", "memory" ], "summary": "Colivelin is a synthetic hybrid of ADNF-9 and a Humanin derivative studied for neuroprotection in laboratory and animal experiments.", "search_blob": "colivelin colivelin cln adnf-derived peptide colivelin peptide colivelin cln adnf-derived peptide colivelin peptide colivelin dosage colivelin dose cognition memory cognition memory cognition memory colivelin is a synthetic hybrid of adnf-9 and a humanin derivative studied for neuroprotection in laboratory and animal experiments. the inspected vendor-associated post describes proposed neuroprotection. it provides no firsthand course, cognitive change or human onset timeline. colivelin is a peptide people look up for focus. colivelin shows up in threads about attention, mental fatigue, or \u201cbrain fog\u201d days. cognitive / nootropic peptides peptide systemic systemic preclinical peptide in central/peripheral injection models; capsule/pin and organ-targeting language is older lore, not established human delivery. systemic whole-body circulating", "legal_class": null }, { "id": 179, "slug": "klotho", "name": "Klotho", "aliases": [ "alpha-Klotho", "s-Klotho", "Klotho protein" ], "type": "Peptide", "category": "Longevity & cellular energy", "goals_use_cases": [ "longevity", "cognition", "cardiovascular" ], "delivery_methods": [ "subcutaneous", "IV" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "klotho", "alpha-Klotho", "s-Klotho", "Klotho protein", "klotho peptide", "klotho dosage", "longevity", "cognition", "cardiovascular" ], "feel_search": [ "longevity", "cognition", "cardiovascular" ], "summary": "Klotho is an aging-related protein, not a single short peptide; consumer products may use different constructs and are discussed for cognition and longevity.", "search_blob": "klotho klotho alpha-klotho s-klotho klotho protein klotho alpha-klotho s-klotho klotho protein klotho peptide klotho dosage longevity cognition cardiovascular longevity cognition cardiovascular longevity cognition cardiovascular klotho is an aging-related protein, not a single short peptide; consumer products may use different constructs and are discussed for cognition and longevity. one evolving account described an altered state, two poor nights of sleep and later perceived mood or cognition benefits. other treatment changes make a typical effect impossible to infer. klotho is a peptide people look up for longevity. improved mood/cognition and eventually improved sleep. longevity & cellular energy peptide systemic systemic biology for native \u03b1-klotho; gray products may be antibodies, fragments or modified proteins, so identity and distribution cannot be assumed. systemic whole-body circulating", "legal_class": null }, { "id": 180, "slug": "17-alpha-estradiol", "name": "17\u03b1-Estradiol", "aliases": [ "17-alpha-estradiol", "17a-E2", "alfatradiol (related)" ], "type": "Non-peptide", "category": "Longevity & cellular energy", "goals_use_cases": [ "longevity", "hormone support", "insulin sensitivity", "cognition", "skin/hair" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Mixed", "misspellings_search_terms": [ "17-alpha-estradiol", "17 alpha estradiol", "17alphaestradiol", "17\u03b1-Estradiol", "17a-E2", "alfatradiol (related)", "longevity", "hormone support", "insulin sensitivity", "cognition", "skin/hair" ], "feel_search": [ "longevity", "hormone support", "insulin sensitivity", "cognition", "skin/hair" ], "summary": "17\u03b1-estradiol is a steroid isomer discussed for longevity and topical-hair use. \u201cNon-feminizing\u201d and \u201cnormalization\u201d are common framing, not established human longevity benefits.", "search_blob": "17\u03b1-estradiol 17-alpha-estradiol 17-alpha-estradiol 17a-e2 alfatradiol (related) 17-alpha-estradiol 17 alpha estradiol 17alphaestradiol 17\u03b1-estradiol 17a-e2 alfatradiol (related) longevity hormone support insulin sensitivity cognition skin/hair longevity hormone support insulin sensitivity cognition skin/hair longevity hormone support insulin sensitivity cognition skin/hair 17\u03b1-estradiol is a steroid isomer discussed for longevity and topical-hair use. \u201cnon-feminizing\u201d and \u201cnormalization\u201d are common framing, not established human longevity benefits. no dependable immediate benefit emerges from this thread. one oral log reports acne; a separate sublingual account describes irritation from its alcohol vehicle. 17\u03b1-estradiol is a steroid isomer discussed for longevity and topical-hair use. \u201cnon-feminizing\u201d and \u201cnormalization\u201d are common framing, not established human longevity benefits. 17\u03b1-estradiol is not 17\u03b2/hrt estradiol. \u201cnon-feminizing\u201d is not a guarantee of no endocrine effects; oral and topical preparations are different. longevity & cellular energy non-peptide mixed mixed \u2014 oral longevity experiments and topical hair (alfatradiol) discussion; not a joint-targeted injection. mixed local systemic", "legal_class": null }, { "id": 181, "slug": "l-carnitine", "name": "L-Carnitine (injectable)", "aliases": [ "L-carnitine 500mg/mL", "carnitine injection", "levocarnitine" ], "type": "Non-peptide", "category": "Mitochondrial & metabolic compounds", "goals_use_cases": [ "fat loss", "energy", "performance", "recovery" ], "delivery_methods": [ "intramuscular", "subcutaneous", "oral", "IV" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "l-carnitine", "l carnitine", "lcarnitine", "L-Carnitine (injectable)", "l-carnitine-(injectable)", "L-carnitine 500mg/mL", "fat loss", "energy", "performance", "recovery" ], "feel_search": [ "fat loss", "energy", "performance", "recovery" ], "summary": "L-carnitine helps transport fatty acids for energy use; oral and injectable forms are discussed for exercise and recovery, while ALCAR has a separate nootropic niche.", "search_blob": "l-carnitine (injectable) l-carnitine l-carnitine 500mg/ml carnitine injection levocarnitine l-carnitine l carnitine lcarnitine l-carnitine (injectable) l-carnitine-(injectable) l-carnitine 500mg/ml fat loss energy performance recovery fat loss energy performance recovery fat loss energy performance recovery l-carnitine helps transport fatty acids for energy use; oral and injectable forms are discussed for exercise and recovery, while alcar has a separate nootropic niche. some injectable users report better pumps or endurance over weeks, while soreness can last into the next day or longer. those accounts cannot be transferred directly to oral carnitine or alcar. l-carnitine (injectable) is a compound people look up for fat loss. older notes describe subtle changes over weeks rather than a stimulant-like effect. mitochondrial & metabolic compounds non-peptide systemic systemic metabolic co-factor / supplement. systemic whole-body circulating", "legal_class": null }, { "id": 182, "slug": "triptorelin", "name": "Triptorelin", "aliases": [ "Trelstar", "Decapeptyl", "GnRH agonist trip" ], "type": "Peptide", "category": "Sexual / reproductive", "goals_use_cases": [ "hormone support", "fertility" ], "delivery_methods": [ "intramuscular", "subcutaneous" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "triptorelin", "Trelstar", "Decapeptyl", "GnRH agonist trip", "triptorelin peptide", "triptorelin dosage", "hormone support", "fertility" ], "feel_search": [ "hormone support", "fertility" ], "summary": "Triptorelin is a synthetic GnRH agonist used in medical injections; short-acting products and long-acting depots have different release profiles.", "search_blob": "triptorelin triptorelin trelstar decapeptyl gnrh agonist trip triptorelin trelstar decapeptyl gnrh agonist trip triptorelin peptide triptorelin dosage hormone support fertility hormone support fertility hormone support fertility triptorelin is a synthetic gnrh agonist used in medical injections; short-acting products and long-acting depots have different release profiles. one multi-drug user reported renewed libido while otherwise feeling much the same, and could not tell what triptorelin contributed. triptorelin is a peptide people look up for fertility. triptorelin first stimulates lh/fsh and sex-steroid release; continuous depot exposure then suppresses the axis over weeks. sexual / reproductive peptide systemic systemic injected gnrh agonist; parent clearance, depot release and endocrine effects have different clocks. systemic whole-body circulating", "legal_class": null }, { "id": 183, "slug": "hmg", "name": "HMG (Menotropin)", "aliases": [ "Human Menopausal Gonadotropin", "Menopur", "hMG 75IU" ], "type": "Peptide", "category": "Sexual / reproductive", "goals_use_cases": [ "fertility", "hormone support" ], "delivery_methods": [ "subcutaneous", "intramuscular" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "hmg", "HMG (Menotropin)", "hmg-(menotropin)", "Human Menopausal Gonadotropin", "Menopur", "hMG 75IU", "fertility", "hormone support" ], "feel_search": [ "fertility", "hormone support" ], "summary": "HMG (menotropins) is a urinary-derived fertility medicine supplying FSH and LH activity; male fertility discussions often combine it with hCG.", "search_blob": "hmg (menotropin) hmg human menopausal gonadotropin menopur hmg 75iu hmg hmg (menotropin) hmg-(menotropin) human menopausal gonadotropin menopur hmg 75iu fertility hormone support fertility hormone support fertility hormone support hmg (menotropins) is a urinary-derived fertility medicine supplying fsh and lh activity; male fertility discussions often combine it with hcg. injection redness, soreness or bruising may be more noticeable than any immediate benefit. fertility response is followed through tests and treatment outcomes over weeks to months. hmg (menotropin) is a peptide people look up for fertility. hmg (menotropin) appears in sexual function and hormone-axis threads. sexual / reproductive peptide systemic systemic fsh/lh activity for fertility care; labeled ovarian stimulation differs from off-label male hmg/hcg use. systemic whole-body circulating", "legal_class": null }, { "id": 184, "slug": "carbetocin", "name": "Carbetocin", "aliases": [ "Pabal", "Duratocin", "long-acting oxytocin analog" ], "type": "Peptide", "category": "Sleep / mood", "goals_use_cases": [ "mood", "anxiety", "libido", "postpartum uterine atony / bleeding prevention (medical)", "PWS anxiousness (investigational)", "PWS hyperphagia (investigational)" ], "delivery_methods": [ "nasal", "subcutaneous" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "carbetocin", "Pabal", "Duratocin", "long-acting oxytocin analog", "carbetocin peptide", "carbetocin dosage", "mood / emotional regulation (PWS caregiver reports)", "anxiety (PWS caregiver reports)", "food preoccupation (PWS caregiver reports)" ], "feel_search": [ "mood / emotional regulation (PWS caregiver reports)", "anxiety (PWS caregiver reports)", "food preoccupation (PWS caregiver reports)" ], "summary": "Carbetocin is a long-acting oxytocin analogue used medically after childbirth; an intranasal formulation was separately studied for Prader-Willi syndrome.", "search_blob": "carbetocin carbetocin pabal duratocin long-acting oxytocin analog carbetocin pabal duratocin long-acting oxytocin analog carbetocin peptide carbetocin dosage mood / emotional regulation (pws caregiver reports) anxiety (pws caregiver reports) food preoccupation (pws caregiver reports) mood anxiety libido postpartum uterine atony / bleeding prevention (medical) pws anxiousness (investigational) pws hyperphagia (investigational) mood / emotional regulation (pws caregiver reports) anxiety (pws caregiver reports) food preoccupation (pws caregiver reports) carbetocin is a long-acting oxytocin analogue used medically after childbirth; an intranasal formulation was separately studied for prader-willi syndrome. caregivers described less anxiety and better day-to-day behavior in some children, despite the intranasal trial missing its overall endpoints. carbetocin is a peptide people look up for bleeding. obstetric use is documented in product information and randomized trials. sleep / mood peptide systemic systemic \u2014 an oxytocin analogue used iv/im after childbirth; intranasal pws research is a separate route and indication. systemic whole-body circulating", "legal_class": null }, { "id": 185, "slug": "davunetide", "name": "Davunetide (NAP)", "aliases": [ "NAP", "NAPVSIPQ", "davunetide peptide" ], "type": "Peptide", "category": "Cognitive / nootropic peptides", "goals_use_cases": [ "cognition", "memory" ], "delivery_methods": [ "nasal" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "davunetide", "Davunetide (NAP)", "davunetide-(nap)", "NAP", "NAPVSIPQ", "davunetide peptide", "cognition", "memory" ], "feel_search": [ "cognition", "memory" ], "summary": "Davunetide (NAP) is an ADNP-derived eight-amino-acid research peptide developed for intranasal neuroprotection studies.", "search_blob": "davunetide (nap) davunetide nap napvsipq davunetide peptide davunetide davunetide (nap) davunetide-(nap) nap napvsipq davunetide peptide cognition memory cognition memory cognition memory davunetide (nap) is an adnp-derived eight-amino-acid research peptide developed for intranasal neuroprotection studies. the inspected post asks about davunetide, but the experience replies concern other nootropics. a detailed commenter explicitly says they have not tried it. davunetide (nap) is a nasal peptide people look up for cognition. davunetide (nap) appears in questions about attention, mental fatigue and brain fog. cognitive / nootropic peptides peptide systemic systemic cns-directed investigational nap octapeptide delivered by metered intranasal spray in human trials; not a khavinson bioregulator. systemic whole-body circulating", "legal_class": null }, { "id": 186, "slug": "fgl", "name": "FGL Peptide", "aliases": [ "FG Loop", "NCAM mimetic", "FGL peptide" ], "type": "Peptide", "category": "Cognitive / nootropic peptides", "goals_use_cases": [ "cognition", "memory" ], "delivery_methods": [ "subcutaneous", "nasal" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "fgl", "FGL Peptide", "fgl-peptide", "FG Loop", "NCAM mimetic", "fgl dosage", "cognition", "memory" ], "feel_search": [ "cognition", "memory" ], "summary": "FGL-family peptides mimic a fragment of neural cell adhesion molecule and are studied for memory-related signaling; FGLL is a specific research form.", "search_blob": "fgl peptide fgl fg loop ncam mimetic fgl peptide fgl fgl peptide fgl-peptide fg loop ncam mimetic fgl dosage cognition memory cognition memory cognition memory fgl-family peptides mimic a fragment of neural cell adhesion molecule and are studied for memory-related signaling; fgll is a specific research form. the accessible reddit thread asks about fgl and dihexa together but gives no completed fgl course. a previously linked experience forum could not be reopened. fgl peptide is a nasal peptide people look up for cognition. fgl peptide shows up in threads about attention, mental fatigue, or \u201cbrain fog\u201d days. cognitive / nootropic peptides peptide systemic synthetic ncam-derived fg-loop mimetic studied intranasally in one small phase i trial; proposed cognitive effects remain mainly preclinical. systemic whole-body circulating", "legal_class": null }, { "id": 187, "slug": "orexin-a", "name": "Orexin A", "aliases": [ "Hypocretin-1", "OX-A", "orexin peptide" ], "type": "Peptide", "category": "Sleep / mood", "goals_use_cases": [ "energy", "focus", "sleep" ], "delivery_methods": [ "nasal" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "orexin-a", "orexin a", "orexina", "Hypocretin-1", "OX-A", "orexin peptide", "energy", "focus", "sleep" ], "feel_search": [ "energy", "focus", "sleep" ], "summary": "Orexin-A is a brain peptide involved in wakefulness and appetite; experimental nasal products are discussed for staying awake.", "search_blob": "orexin a orexin-a hypocretin-1 ox-a orexin peptide orexin-a orexin a orexina hypocretin-1 ox-a orexin peptide energy focus sleep energy focus sleep energy focus sleep orexin-a is a brain peptide involved in wakefulness and appetite; experimental nasal products are discussed for staying awake. orexin a, a peptide people look up for energy. one intranasal user recalled about four hours of wakefulness without a stimulant-like feeling; others described little or no effect. sleep / mood peptide systemic wake/appetite neuropeptide; intranasal community use and systemic research do not establish selective brain delivery. systemic whole-body circulating", "legal_class": null }, { "id": 188, "slug": "thymopentin", "name": "Thymopentin", "aliases": [ "TP-5", "RKDVY", "thymopoietin pentapeptide" ], "type": "Peptide", "category": "Immune / antimicrobial", "goals_use_cases": [ "immune", "recovery" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "thymopentin", "TP-5", "RKDVY", "thymopoietin pentapeptide", "thymopentin peptide", "thymopentin dosage", "immune", "recovery" ], "feel_search": [ "immune", "recovery" ], "summary": "Thymopentin (TP-5) is a synthetic five-amino-acid fragment of thymopoietin studied for immune function.", "search_blob": "thymopentin thymopentin tp-5 rkdvy thymopoietin pentapeptide thymopentin tp-5 rkdvy thymopoietin pentapeptide thymopentin peptide thymopentin dosage immune recovery immune recovery immune recovery thymopentin (tp-5) is a synthetic five-amino-acid fragment of thymopoietin studied for immune function. the inspected purchaser thread has no personal result after use; its uti-prevention story is second-hand. thymopentin is a peptide people look up for immune support. frame benefits around immune (tp5) function and \u201cnormalization\u201d language. immune / antimicrobial peptide systemic systemic immune-modulation research around a defined thymopoietin pentapeptide; plasma degradation is rapid ex vivo. systemic whole-body circulating", "legal_class": null }, { "id": 189, "slug": "ac-sdkp", "name": "Ac-SDKP", "aliases": [ "N-acetyl-Ser-Asp-Lys-Pro", "AcSDKP", "thymosin beta-4 metabolite" ], "type": "Peptide", "category": "Healing & repair", "goals_use_cases": [ "anti fibrotic", "cardiovascular", "recovery" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "ac-sdkp", "ac sdkp", "acsdkp", "N-acetyl-Ser-Asp-Lys-Pro", "thymosin beta-4 metabolite", "ac-sdkp peptide", "anti fibrotic", "cardiovascular", "recovery" ], "feel_search": [ "anti fibrotic", "cardiovascular", "recovery" ], "summary": "Ac-SDKP is a four-amino-acid fragment of thymosin-\u03b24 studied for reducing tissue scarring; it differs from the fragment sold as TB-500.", "search_blob": "ac-sdkp ac-sdkp n-acetyl-ser-asp-lys-pro acsdkp thymosin beta-4 metabolite ac-sdkp ac sdkp acsdkp n-acetyl-ser-asp-lys-pro thymosin beta-4 metabolite ac-sdkp peptide anti fibrotic cardiovascular recovery anti fibrotic cardiovascular recovery anti fibrotic cardiovascular recovery ac-sdkp is a four-amino-acid fragment of thymosin-\u03b24 studied for reducing tissue scarring; it differs from the fragment sold as tb-500. the inspected thread discusses which thymosin fragment is in a product. it does not establish a firsthand benefit or a reliable feel timeline. ac-sdkp is a peptide people look up for scar tissue. ac-sdkp is discussed for soft-tissue bounce-back, joint noise, or post-strain continuity. healing & repair peptide systemic endogenous peptide studied for systemic anti-fibrotic effects; organ-focused discussion does not establish local targeting or oral delivery. systemic whole-body circulating", "legal_class": null }, { "id": 190, "slug": "apitegromab", "name": "Apitegromab", "aliases": [ "SRK-015", "apitegromab antibody" ], "type": "Peptide", "category": "Growth factors / muscle", "goals_use_cases": [ "muscle growth", "performance" ], "delivery_methods": [ "IV" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "apitegromab", "SRK-015", "apitegromab antibody", "apitegromab peptide", "apitegromab dosage", "Apitegromab dose", "muscle growth", "performance" ], "feel_search": [ "muscle growth", "performance" ], "summary": "Apitegromab is an investigational antibody that blocks myostatin activation, studied for muscle function in spinal muscular atrophy.", "search_blob": "apitegromab apitegromab srk-015 apitegromab antibody apitegromab srk-015 apitegromab antibody apitegromab peptide apitegromab dosage apitegromab dose muscle growth performance muscle growth performance muscle growth performance apitegromab is an investigational antibody that blocks myostatin activation, studied for muscle function in spinal muscular atrophy. patients discuss hoped-for small functional gains and the limits of longstanding disease. the inspected conversation is expectation, not a treatment diary. apitegromab is an antibody people look up for muscle. the older site-reaction / gi / mood template described general injected or oral agents, not verified apitegromab experiences. growth factors / muscle peptide systemic systemic anti-myostatin antibody. systemic whole-body circulating", "legal_class": null }, { "id": 191, "slug": "gdf-11", "name": "GDF-11", "aliases": [ "GDF11", "growth differentiation factor 11" ], "type": "Peptide", "category": "Growth factors / muscle", "goals_use_cases": [ "longevity", "muscle growth", "cognition" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "gdf-11", "gdf 11", "gdf11", "growth differentiation factor 11", "gdf-11 peptide", "gdf-11 dosage", "longevity", "muscle growth", "cognition" ], "feel_search": [ "longevity", "muscle growth", "cognition" ], "summary": "GDF11 is a growth-factor protein discussed in longevity circles as a possible aging signal; it is different from short organ-targeted bioregulator peptides.", "search_blob": "gdf-11 gdf-11 gdf11 growth differentiation factor 11 gdf-11 gdf 11 gdf11 growth differentiation factor 11 gdf-11 peptide gdf-11 dosage longevity muscle growth cognition longevity muscle growth cognition longevity muscle growth cognition gdf11 is a growth-factor protein discussed in longevity circles as a possible aging signal; it is different from short organ-targeted bioregulator peptides. accounts range from no noticeable change to claimed endurance gains. one long-term tracker reported none of the promoted reaction-time or heart-rate-variability improvements. these uncontrolled reports do not establish an anti-aging benefit. gdf-11 is a peptide people look up for longevity. the reviewed accounts do not establish what most people feel after one gdf11 dose. growth factors / muscle peptide systemic systemic \u2014 a circulating tgf-\u03b2-family growth factor; research and self-reports concern whole-body exposure, not an organ-specific capsule. systemic whole-body circulating", "legal_class": null }, { "id": 192, "slug": "bromantane", "name": "Bromantane", "aliases": [ "Ladasten", "NP-160", "bromantan" ], "type": "Non-peptide", "category": "Cognitive / nootropic peptides", "goals_use_cases": [ "energy", "performance", "focus", "mood" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "bromantane", "Ladasten", "NP-160", "bromantan", "bromantane peptide", "bromantane dosage", "energy", "performance", "focus", "mood" ], "feel_search": [ "energy", "performance", "focus", "mood" ], "summary": "Bromantane is an oral small-molecule pill, not a peptide, sold as Ladasten in Russia and discussed for fatigue, motivation and easier task initiation.", "search_blob": "bromantane bromantane ladasten np-160 bromantan bromantane ladasten np-160 bromantan bromantane peptide bromantane dosage energy performance focus mood energy performance focus mood energy performance focus mood bromantane is an oral small-molecule pill, not a peptide, sold as ladasten in russia and discussed for fatigue, motivation and easier task initiation. favorable accounts describe easier task initiation and less mental friction. others report no benefit, anxious stimulation or insomnia; oral and nasal experiences differ. bromantane (ladasten) is an oral small-molecule pill, not a peptide, for fatigue. easier task initiation, calmer drive and less mental friction recur in favorable accounts. cognitive / nootropic peptides non-peptide systemic taken by mouth for whole-body fatigue and motivation talk \u2014 not a peptide and not a typical stimulant. systemic whole-body circulating", "legal_class": null }, { "id": 193, "slug": "acetyl-tetrapeptide-3", "name": "Acetyl Tetrapeptide-3", "aliases": [ "Capixyl peptide", "acetyl tetrapeptide-3 hair" ], "type": "Peptide", "category": "Skin, hair & tissue remodeling", "goals_use_cases": [ "skin/hair", "recovery" ], "delivery_methods": [ "topical" ], "discussion_popularity": "Emerging", "reach": "Local", "misspellings_search_terms": [ "acetyl-tetrapeptide-3", "acetyl tetrapeptide 3", "acetyltetrapeptide3", "Acetyl Tetrapeptide-3", "Capixyl peptide", "acetyl tetrapeptide-3 hair", "skin/hair", "recovery" ], "feel_search": [ "skin/hair", "recovery" ], "summary": "Acetyl Tetrapeptide-3 is a cosmetic peptide used in scalp and lash products; Capixyl combines it with red-clover extract.", "search_blob": "acetyl tetrapeptide-3 acetyl-tetrapeptide-3 capixyl peptide acetyl tetrapeptide-3 hair acetyl-tetrapeptide-3 acetyl tetrapeptide 3 acetyltetrapeptide3 acetyl tetrapeptide-3 capixyl peptide acetyl tetrapeptide-3 hair skin/hair recovery skin/hair recovery skin/hair recovery acetyl tetrapeptide-3 is a cosmetic peptide used in scalp and lash products; capixyl combines it with red-clover extract. one multi-ingredient serum review reports brief early scalp tingling and less shedding by week three. it cannot attribute that change to this peptide alone. acetyl tetrapeptide-3 is a peptide people look up for hair. one describes fuller-looking hair the next day without believing hair loss had improved. skin, hair & tissue remodeling peptide local local \u2014 a scalp/skin serum, not a whole-body shot. local site pin topical", "legal_class": null }, { "id": 194, "slug": "pramlintide", "name": "Pramlintide", "aliases": [ "Symlin", "pramlintide acetate", "amylin analog pramlintide" ], "type": "Peptide", "category": "Metabolic / GLP-1 class", "goals_use_cases": [ "fat loss", "appetite suppression", "insulin sensitivity" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "pramlintide", "Symlin", "pramlintide acetate", "amylin analog pramlintide", "pramlintide peptide", "pramlintide dosage", "fat loss", "appetite suppression", "insulin sensitivity" ], "feel_search": [ "fat loss", "appetite suppression", "insulin sensitivity" ], "summary": "Pramlintide (Symlin) is an injectable amylin analogue used with insulin for mealtime glucose control and discussed for satiety.", "search_blob": "pramlintide pramlintide symlin pramlintide acetate amylin analog pramlintide pramlintide symlin pramlintide acetate amylin analog pramlintide pramlintide peptide pramlintide dosage fat loss appetite suppression insulin sensitivity fat loss appetite suppression insulin sensitivity fat loss appetite suppression insulin sensitivity pramlintide (symlin) is an injectable amylin analogue used with insulin for mealtime glucose control and discussed for satiety. one long-term user described light early nausea that later faded, but found injections before every meal burdensome. pramlintide is a peptide people look up for fat loss. slows gastric emptying, suppresses glucagon, increases satiety signaling. metabolic / glp-1 class peptide systemic systemic amylin-pathway peptide for meal-time metabolic control. systemic whole-body circulating", "legal_class": null }, { "id": 195, "slug": "teduglutide", "name": "Teduglutide", "aliases": [ "Gattex", "Revestive", "GLP-2 analog" ], "type": "Peptide", "category": "Gut & inflammation peptides", "goals_use_cases": [ "gut health", "recovery" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "teduglutide", "Gattex", "Revestive", "GLP-2 analog", "teduglutide peptide", "teduglutide dosage", "gut health", "recovery" ], "feel_search": [ "gut health", "recovery" ], "summary": "Teduglutide (Gattex/Revestive) is a GLP-2 analogue used for short-bowel syndrome to improve intestinal absorption.", "search_blob": "teduglutide teduglutide gattex revestive glp-2 analog teduglutide gattex revestive glp-2 analog teduglutide peptide teduglutide dosage gut health recovery gut health recovery gut health recovery teduglutide (gattex/revestive) is a glp-2 analogue used for short-bowel syndrome to improve intestinal absorption. one person after major bowel resection reported better symptom control alongside bloating and gas; longstanding no-burp symptoms complicate attribution. teduglutide is a peptide people look up for gut. teduglutide improved symptom control with few negative effects. gut & inflammation peptides peptide systemic systemic glp-2 analog for sbs. systemic whole-body circulating", "legal_class": null }, { "id": 196, "slug": "anamorelin", "name": "Anamorelin", "aliases": [ "ONO-7643", "Adlumiz", "anamorelin HCl" ], "type": "Peptide", "category": "Growth hormone axis", "goals_use_cases": [ "muscle growth", "appetite suppression", "performance", "appetite stimulation" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "anamorelin", "ONO-7643", "Adlumiz", "anamorelin HCl", "anamorelin peptide", "anamorelin dosage", "muscle growth", "appetite stimulation", "performance" ], "feel_search": [ "muscle growth", "appetite stimulation", "performance" ], "summary": "Anamorelin is an oral ghrelin-receptor drug developed to increase appetite and lean mass in cancer-related wasting.", "search_blob": "anamorelin anamorelin ono-7643 adlumiz anamorelin hcl anamorelin ono-7643 adlumiz anamorelin hcl anamorelin peptide anamorelin dosage muscle growth appetite stimulation performance muscle growth appetite suppression performance appetite stimulation muscle growth appetite stimulation performance anamorelin is an oral ghrelin-receptor drug developed to increase appetite and lean mass in cancer-related wasting. one early self-log reports no effect after the first exposure, then nausea, fatigue and breathlessness around a gym session. that is not an appetite-benefit estimate. anamorelin is an oral compound people look up for appetite and muscle. cachexia programs reported appetite and lbm signals. growth hormone axis peptide systemic systemic oral ghrelin mimetic. systemic whole-body circulating", "legal_class": null }, { "id": 197, "slug": "svetinorm", "name": "Svetinorm", "aliases": [ "Svetinorm peptide", "liver peptide complex" ], "type": "Peptide", "category": "Organ bioregulators", "goals_use_cases": [ "longevity", "recovery" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "svetinorm", "Svetinorm peptide", "liver peptide complex", "svetinorm dosage", "Svetinorm dose", "svetinorm research", "longevity", "recovery" ], "feel_search": [ "longevity", "recovery" ], "summary": "Svetinorm is a liver-targeted product in the Russian peptide-bioregulator tradition, marketed for liver support.", "search_blob": "svetinorm svetinorm svetinorm peptide liver peptide complex svetinorm svetinorm peptide liver peptide complex svetinorm dosage svetinorm dose svetinorm research longevity recovery longevity recovery longevity recovery svetinorm is a liver-targeted product in the russian peptide-bioregulator tradition, marketed for liver support. one multi-product user called svetinorm helpful, but the thread does not isolate its effects; another person only reported ordering it. svetinorm is a peptide people look up for longevity. said they had ordered ovagen and svetinorm but supplied no outcome follow-up. organ bioregulators peptide systemic oral liver-tissue peptide supplement sold in bioregulator culture; organ targeting and human benefit remain unproven. systemic whole-body circulating", "legal_class": null }, { "id": 198, "slug": "sigumir", "name": "Sigumir", "aliases": [ "Sigumir peptide", "cartilage-bone bioregulator" ], "type": "Peptide", "category": "Organ bioregulators", "goals_use_cases": [ "joints & tendons", "bone health", "recovery" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "sigumir", "Sigumir peptide", "cartilage-bone bioregulator", "sigumir dosage", "Sigumir dose", "sigumir research", "joints & tendons", "bone health", "recovery" ], "feel_search": [ "joints & tendons", "bone health", "recovery" ], "summary": "Sigumir is a cartilage-derived mixture of small peptides from calves or pigs, marketed for joints; it differs from the single peptide Cartalax.", "search_blob": "sigumir sigumir sigumir peptide cartilage-bone bioregulator sigumir sigumir peptide cartilage-bone bioregulator sigumir dosage sigumir dose sigumir research joints & tendons bone health recovery joints & tendons bone health recovery joints & tendons bone health recovery sigumir is a cartilage-derived mixture of small peptides from calves or pigs, marketed for joints; it differs from the single peptide cartalax. one commenter said their knees felt more solid after a box; the original poster pursued prp, so those are separate histories. sigumir is a peptide people look up for joints. community and regional literature frame benefits around cartilage / joints function and \u201cnormalization\u201d language. organ bioregulators peptide systemic cartilage/joint-framed oral extract; organ-targeting language does not establish selective human delivery. systemic whole-body circulating", "legal_class": null }, { "id": 199, "slug": "vladonix", "name": "Vladonix", "aliases": [ "Vladonix peptide", "thymus bioregulator complex" ], "type": "Peptide", "category": "Organ bioregulators", "goals_use_cases": [ "immune", "longevity" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "vladonix", "Vladonix peptide", "thymus bioregulator complex", "vladonix dosage", "Vladonix dose", "vladonix research", "immune", "longevity" ], "feel_search": [ "immune", "longevity" ], "summary": "Vladonix is a thymus-targeted product in the Russian peptide-bioregulator tradition, marketed for immune support.", "search_blob": "vladonix vladonix vladonix peptide thymus bioregulator complex vladonix vladonix peptide thymus bioregulator complex vladonix dosage vladonix dose vladonix research immune longevity immune longevity immune longevity vladonix is a thymus-targeted product in the russian peptide-bioregulator tradition, marketed for immune support. one person reported better sleep, concentration, mood and digestion while trying many bioregulators together, without identifying vladonix's contribution. vladonix is an oral peptide people look up for immune support. the available report did not isolate vladonix or give a product-specific onset. organ bioregulators peptide systemic systemic oral thymus-extract product with organ-targeted marketing; not a local thymus treatment. systemic whole-body circulating", "legal_class": null }, { "id": 200, "slug": "bonomarlot", "name": "Bonomarlot", "aliases": [ "Bonomarlot peptide", "bone-marrow bioregulator" ], "type": "Peptide", "category": "Organ bioregulators", "goals_use_cases": [ "bone health", "immune", "longevity" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "bonomarlot", "Bonomarlot peptide", "bone-marrow bioregulator", "bonomarlot dosage", "Bonomarlot dose", "bonomarlot research", "bone health", "immune", "longevity" ], "feel_search": [ "bone health", "immune", "longevity" ], "summary": "Bonomarlot is a bone-marrow bioregulator product discussed for blood-cell and iron-related concerns; capsule reports are sparse.", "search_blob": "bonomarlot bonomarlot bonomarlot peptide bone-marrow bioregulator bonomarlot bonomarlot peptide bone-marrow bioregulator bonomarlot dosage bonomarlot dose bonomarlot research bone health immune longevity bone health immune longevity bone health immune longevity bonomarlot is a bone-marrow bioregulator product discussed for blood-cell and iron-related concerns; capsule reports are sparse. one long-term capsule user reports improved ferritin and hemoglobin after earlier iron treatments disappointed them. this is a lab self-report, not a known immediate feeling. bonomarlot is an oral peptide people look up for recovery. community and regional literature frame benefits around bone marrow / blood function and \u201cnormalization\u201d language. organ bioregulators peptide systemic bone-marrow and blood-support discussion around an oral capsule; organ-focused claims are not a local marrow treatment. systemic whole-body circulating", "legal_class": null }, { "id": 201, "slug": "stamakort", "name": "Stamakort", "aliases": [ "Stamakort peptide", "stomach-mucosa bioregulator" ], "type": "Peptide", "category": "Organ bioregulators", "goals_use_cases": [ "gut health", "recovery" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "stamakort", "Stamakort peptide", "stomach-mucosa bioregulator", "stamakort dosage", "Stamakort dose", "stamakort research", "gut health", "recovery" ], "feel_search": [ "gut health", "recovery" ], "summary": "Stamakort is a stomach-targeted product in the Russian peptide-bioregulator tradition, marketed for gastrointestinal mucosal support.", "search_blob": "stamakort stamakort stamakort peptide stomach-mucosa bioregulator stamakort stamakort peptide stomach-mucosa bioregulator stamakort dosage stamakort dose stamakort research gut health recovery gut health recovery gut health recovery stamakort is a stomach-targeted product in the russian peptide-bioregulator tradition, marketed for gastrointestinal mucosal support. one user taking stamakort alongside other products could not tell whether it affected their stomach and reported no negative effect then. stamakort is an oral peptide people look up for gut. community and regional literature frame benefits around stomach / gi mucosa function and \u201cnormalization\u201d language. organ bioregulators peptide systemic targeted in marketing to the stomach, but documented use is oral capsules; systemic absorption and organ-selective delivery are unestablished. systemic whole-body circulating", "legal_class": null }, { "id": 202, "slug": "ventfort", "name": "Ventfort", "aliases": [ "Ventfort peptide", "vessel bioregulator complex" ], "type": "Peptide", "category": "Organ bioregulators", "goals_use_cases": [ "cardiovascular", "longevity" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "ventfort", "Ventfort peptide", "vessel bioregulator complex", "ventfort dosage", "Ventfort dose", "ventfort research", "cardiovascular", "longevity" ], "feel_search": [ "cardiovascular", "longevity" ], "summary": "Ventfort (A-3) is a blood-vessel-tissue-derived mixture of peptide fractions marketed for vascular support.", "search_blob": "ventfort ventfort ventfort peptide vessel bioregulator complex ventfort ventfort peptide vessel bioregulator complex ventfort dosage ventfort dose ventfort research cardiovascular longevity cardiovascular longevity cardiovascular longevity ventfort (a-3) is a blood-vessel-tissue-derived mixture of peptide fractions marketed for vascular support. one person reported better sleep and wearable recovery scores while taking ventfort with chelohart and svetinorm, and acknowledged possible placebo. ventfort is a peptide people look up for longevity. community and regional literature frame benefits around vascular wall / vessels function and \u201cnormalization\u201d language. organ bioregulators peptide systemic vessel-targeted tissue-derived peptide-fraction product; reviewed sources established oral retail forms, not an injectable ventfort route. systemic whole-body circulating", "legal_class": null }, { "id": 203, "slug": "gotratix", "name": "Gotratix", "aliases": [ "Gotratix peptide", "muscle bioregulator" ], "type": "Peptide", "category": "Organ bioregulators", "goals_use_cases": [ "muscle growth", "recovery" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "gotratix", "Gotratix peptide", "muscle bioregulator", "gotratix dosage", "Gotratix dose", "gotratix research", "muscle growth", "recovery" ], "feel_search": [ "muscle growth", "recovery" ], "summary": "Gotratix (A-18) is an animal muscle-derived peptide mixture sold in capsules, discussed for training recovery and muscle maintenance.", "search_blob": "gotratix gotratix gotratix peptide muscle bioregulator gotratix gotratix peptide muscle bioregulator gotratix dosage gotratix dose gotratix research muscle growth recovery muscle growth recovery muscle growth recovery gotratix (a-18) is an animal muscle-derived peptide mixture sold in capsules, discussed for training recovery and muscle maintenance. gotratix is an oral peptide people look up for muscle. one user later described reduced soreness; a separate two-month solo user reported no recovery or training benefit. organ bioregulators peptide systemic an oral animal-muscle peptide mixture marketed for skeletal muscle; no injectable gotratix or human distribution study was verified. systemic whole-body circulating", "legal_class": null }, { "id": 204, "slug": "libidon", "name": "Libidon", "aliases": [ "Libidon peptide", "prostate bioregulator complex" ], "type": "Peptide", "category": "Organ bioregulators", "goals_use_cases": [ "sexual health", "hormone support", "recovery" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "libidon", "Libidon peptide", "prostate bioregulator complex", "libidon dosage", "Libidon dose", "libidon research", "sexual health", "hormone support", "recovery" ], "feel_search": [ "sexual health", "hormone support", "recovery" ], "summary": "Libidon A-16 is an animal prostate-derived peptide mixture sold in capsules, discussed for urinary symptoms and prostate support.", "search_blob": "libidon libidon libidon peptide prostate bioregulator complex libidon libidon peptide prostate bioregulator complex libidon dosage libidon dose libidon research sexual health hormone support recovery sexual health hormone support recovery sexual health hormone support recovery libidon a-16 is an animal prostate-derived peptide mixture sold in capsules, discussed for urinary symptoms and prostate support. some oral users report gi upset first, then possible urinary or erection changes over weeks. tadalafil, caffeine changes and fluctuating symptoms make its contribution unclear. libidon a-16 is an oral peptide complex. community and regional literature frame benefits around prostate / male urology function and \u201cnormalization\u201d language. organ bioregulators peptide systemic systemic oral product with prostate-targeted marketing; human tissue distribution has not been established. systemic whole-body circulating", "legal_class": null }, { "id": 205, "slug": "ac-262", "name": "AC-262", "aliases": [ "AC262", "AC-262536" ], "type": "Non-peptide", "category": "Performance / endurance", "goals_use_cases": [ "muscle growth", "performance" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "ac-262", "ac 262", "ac262", "AC-262536", "ac-262 peptide", "ac-262 dosage", "muscle growth", "performance" ], "feel_search": [ "muscle growth", "performance" ], "summary": "AC-262 is an oral SARM. Reports range from an early mental lift to no worthwhile strength change; one 4-week Cardarine-stacked run described bloating and lackluster results.", "search_blob": "ac-262 ac-262 ac262 ac-262536 ac-262 ac 262 ac262 ac-262536 ac-262 peptide ac-262 dosage muscle growth performance muscle growth performance muscle growth performance ac-262 is an oral sarm. reports range from an early mental lift to no worthwhile strength change; one 4-week cardarine-stacked run described bloating and lackluster results. one user on testosterone reports early energy and mood lift, then more fullness; they describe little strength change. that stack cannot isolate ac-262. ac-262 is an oral sarm. reports range from an early mental lift to no worthwhile strength change; one 4-week cardarine-stacked run described bloating and lackluster results. performance / endurance non-peptide systemic systemic sarm research chem. systemic whole-body circulating", "legal_class": null }, { "id": 206, "slug": "lgd-3303", "name": "LGD-3303", "aliases": [ "LGD3303", "LGD 3303" ], "type": "Non-peptide", "category": "Performance / endurance", "goals_use_cases": [ "muscle growth", "performance", "bone health" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "lgd-3303", "lgd 3303", "lgd3303", "lgd-3303 peptide", "lgd-3303 dosage", "LGD-3303 dose", "muscle growth", "performance", "bone health" ], "feel_search": [ "muscle growth", "performance", "bone health" ], "summary": "LGD-3303 is an experimental nonsteroidal androgen-receptor modulator, discussed for muscle and strength; it is a different molecule from LGD-4033.", "search_blob": "lgd-3303 lgd-3303 lgd3303 lgd 3303 lgd-3303 lgd 3303 lgd3303 lgd-3303 peptide lgd-3303 dosage lgd-3303 dose muscle growth performance bone health muscle growth performance bone health muscle growth performance bone health lgd-3303 is an experimental nonsteroidal androgen-receptor modulator, discussed for muscle and strength; it is a different molecule from lgd-4033. a week-four account described more definition, weight gain and better lifts, but the visible exchange did not settle whether the tablets were lgd-3303 or lgd-4033. it cannot establish a typical 3303 response. lgd-3303 is an oral compound people look up for muscle. lgd-3303 is discussed for recomp, strength continuity, or soft-tissue recovery depending on class. do not mix up with lgd-4033 charts. performance / endurance non-peptide systemic systemic oral sarm research chemical; human pharmacokinetics and clinical efficacy are not established. systemic whole-body circulating", "legal_class": null }, { "id": 207, "slug": "meldonium", "name": "Meldonium", "aliases": [ "Mildronate", "MET-88", "meldonium dihydrate" ], "type": "Non-peptide", "category": "Performance / endurance", "goals_use_cases": [ "performance", "cardiovascular", "recovery" ], "delivery_methods": [ "oral", "IV" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "meldonium", "Mildronate", "MET-88", "meldonium dihydrate", "meldonium peptide", "meldonium dosage", "performance", "cardiovascular", "recovery" ], "feel_search": [ "performance", "cardiovascular", "recovery" ], "summary": "Meldonium (Mildronate) is a metabolic drug that affects fuel use, discussed for fatigue and endurance as well as regional cardiac uses.", "search_blob": "meldonium meldonium mildronate met-88 meldonium dihydrate meldonium mildronate met-88 meldonium dihydrate meldonium peptide meldonium dosage performance cardiovascular recovery performance cardiovascular recovery performance cardiovascular recovery meldonium (mildronate) is a metabolic drug that affects fuel use, discussed for fatigue and endurance as well as regional cardiac uses. some report easier physical activity, others only slight recovery or no energy gain. fatigue, disrupted sleep or a crash also appear; the small number of accounts does not establish a typical response. meldonium is an oral compound people look up for recovery. athletes discussed endurance benefits \u2014 evidence and ethics are contested; banned in competition. performance / endurance non-peptide systemic systemic metabolic modulator reported orally; intravenous administration appears in medical and pharmacokinetic contexts. systemic whole-body circulating", "legal_class": null }, { "id": 208, "slug": "sotatercept", "name": "Sotatercept", "aliases": [ "Winrevair", "ACE-011 (related)", "sotatercept-csrk" ], "type": "Peptide", "category": "Growth factors / muscle", "goals_use_cases": [ "muscle growth", "cardiovascular" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "sotatercept", "Winrevair", "ACE-011 (related)", "sotatercept-csrk", "sotatercept peptide", "sotatercept dosage", "muscle growth", "cardiovascular" ], "feel_search": [ "muscle growth", "cardiovascular" ], "summary": "Sotatercept (Winrevair) is an activin-signaling inhibitor used for pulmonary arterial hypertension, a serious blood-vessel disease of the lungs.", "search_blob": "sotatercept sotatercept winrevair ace-011 (related) sotatercept-csrk sotatercept winrevair ace-011 (related) sotatercept-csrk sotatercept peptide sotatercept dosage muscle growth cardiovascular muscle growth cardiovascular muscle growth cardiovascular sotatercept (winrevair) is an activin-signaling inhibitor used for pulmonary arterial hypertension, a serious blood-vessel disease of the lungs. patients report easier breathing or no clear subjective improvement; some describe fatigue, headaches or diarrhea after treatment. sotatercept is a peptide people look up for breathing. clinical program improved outcomes in pulmonary arterial hypertension. growth factors / muscle peptide systemic systemic actriia fusion biologic for pah. systemic whole-body circulating", "legal_class": null }, { "id": 209, "slug": "lac-phe", "name": "Lac-Phe", "aliases": [ "Lactoyl-Phenylalanine", "N-lactoyl-phenylalanine" ], "type": "Non-peptide", "category": "Performance / endurance", "goals_use_cases": [ "performance", "appetite suppression", "fat loss" ], "delivery_methods": [ "oral", "subcutaneous" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "lac-phe", "lac phe", "lacphe", "Lactoyl-Phenylalanine", "N-lactoyl-phenylalanine", "lac-phe peptide", "performance", "appetite suppression", "fat loss" ], "feel_search": [ "performance", "appetite suppression", "fat loss" ], "summary": "Lac-Phe is a metabolite formed from lactate and phenylalanine, studied as an exercise-linked signal that may influence appetite.", "search_blob": "lac-phe lac-phe lactoyl-phenylalanine n-lactoyl-phenylalanine lac-phe lac phe lacphe lactoyl-phenylalanine n-lactoyl-phenylalanine lac-phe peptide performance appetite suppression fat loss performance appetite suppression fat loss performance appetite suppression fat loss lac-phe is a metabolite formed from lactate and phenylalanine, studied as an exercise-linked signal that may influence appetite. lac-phe is a compound looked up for appetite. the checked community discussions contained no product-verified exogenous lac-phe log, so there is no supported subjective checkpoint. performance / endurance non-peptide systemic endogenous circulating exercise metabolite; exogenous human use remains experimental, and no oral or subq consumer route was verified. systemic whole-body circulating", "legal_class": null }, { "id": 210, "slug": "pielotax", "name": "Pielotax", "aliases": [ "Pielotax peptide", "kidney bioregulator" ], "type": "Peptide", "category": "Organ bioregulators", "goals_use_cases": [ "recovery", "longevity" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "pielotax", "Pielotax peptide", "kidney bioregulator", "pielotax dosage", "Pielotax dose", "pielotax research", "recovery", "longevity" ], "feel_search": [ "recovery", "longevity" ], "summary": "Pielotax is a kidney-targeted product in the Russian peptide-bioregulator tradition; organ-support claims have limited independent human evidence.", "search_blob": "pielotax pielotax pielotax peptide kidney bioregulator pielotax pielotax peptide kidney bioregulator pielotax dosage pielotax dose pielotax research recovery longevity recovery longevity recovery longevity pielotax is a kidney-targeted product in the russian peptide-bioregulator tradition; organ-support claims have limited independent human evidence. a commercial diary described less dizziness with a kidney-product stack; changing product names and several other agents prevent isolating pielotax. pielotax is an oral peptide people look up for recovery. community and regional literature frame benefits around kidney function and \u201cnormalization\u201d language. organ bioregulators peptide systemic aimed at one organ in the writeups, but people still take it as a whole-body capsule. systemic whole-body circulating", "legal_class": null }, { "id": 211, "slug": "visoluten", "name": "Visoluten", "aliases": [ "Visoluten peptide", "retina bioregulator" ], "type": "Peptide", "category": "Organ bioregulators", "goals_use_cases": [ "cognition", "longevity" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "visoluten", "Visoluten peptide", "retina bioregulator", "visoluten dosage", "Visoluten dose", "visoluten research", "cognition", "longevity" ], "feel_search": [ "cognition", "longevity" ], "summary": "Visoluten is a retina-targeted product in the Russian peptide-bioregulator tradition, marketed for vision support.", "search_blob": "visoluten visoluten visoluten peptide retina bioregulator visoluten visoluten peptide retina bioregulator visoluten dosage visoluten dose visoluten research cognition longevity cognition longevity cognition longevity visoluten is a retina-targeted product in the russian peptide-bioregulator tradition, marketed for vision support. one reader described using weaker reading glasses; other accounts vary, and self-reported glasses strength does not prove a retinal change. visoluten is an oral peptide people look up for vision. community and regional literature frame benefits around retina / vision function and \u201cnormalization\u201d language. organ bioregulators peptide systemic systemic oral or lingual product with retina- or vision-targeted marketing; not a local eye treatment. systemic whole-body circulating", "legal_class": null }, { "id": 212, "slug": "thymogen", "name": "Thymogen", "aliases": [ "Thymogen peptide", "Glu-Trp dipeptide", "EW dipeptide" ], "type": "Peptide", "category": "Organ bioregulators", "goals_use_cases": [ "immune", "recovery" ], "delivery_methods": [ "nasal", "subcutaneous", "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "thymogen", "Thymogen peptide", "Glu-Trp dipeptide", "EW dipeptide", "thymogen dosage", "Thymogen dose", "immune", "recovery" ], "feel_search": [ "immune", "recovery" ], "summary": "Thymogen, also called oglufanide, is the synthetic Glu-Trp dipeptide derived from thymus-extract research and discussed for immune effects.", "search_blob": "thymogen thymogen thymogen peptide glu-trp dipeptide ew dipeptide thymogen thymogen peptide glu-trp dipeptide ew dipeptide thymogen dosage thymogen dose immune recovery immune recovery immune recovery thymogen, also called oglufanide, is the synthetic glu-trp dipeptide derived from thymus-extract research and discussed for immune effects. one person reported less food-triggered discomfort alongside substantial water retention and constipation. thymogen is a peptide people look up for immune support. community and regional literature frame benefits around immune function and \u201cnormalization\u201d language. organ bioregulators peptide systemic systemic immune-modulation discussion around a defined glu-trp dipeptide; route and product form vary. systemic whole-body circulating", "legal_class": null }, { "id": 213, "slug": "tuftsin", "name": "Tuftsin", "aliases": [ "Thr-Lys-Pro-Arg", "tuftsin tetrapeptide" ], "type": "Peptide", "category": "Immune / antimicrobial", "goals_use_cases": [ "immune", "recovery" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "tuftsin", "Thr-Lys-Pro-Arg", "tuftsin tetrapeptide", "tuftsin peptide", "tuftsin dosage", "Tuftsin dose", "immune", "recovery" ], "feel_search": [ "immune", "recovery" ], "summary": "Tuftsin is a natural four-amino-acid fragment of the immune protein IgG, studied for immune cells that engulf germs; Selank is a modified analogue.", "search_blob": "tuftsin tuftsin thr-lys-pro-arg tuftsin tetrapeptide tuftsin thr-lys-pro-arg tuftsin tetrapeptide tuftsin peptide tuftsin dosage tuftsin dose immune recovery immune recovery immune recovery tuftsin is a natural four-amino-acid fragment of the immune protein igg, studied for immune cells that engulf germs; selank is a modified analogue. the inspected community post discusses selank, with no direct tuftsin experience to summarize. tuftsin is a peptide people look up for immune support. reported clinical and leukocyte outcomes, not a consumer felt-onset or oral gi/mood timeline. immune / antimicrobial peptide systemic endogenous immune-signaling tetrapeptide studied systemically by iv; no organ-specific capsule exposure or consumer injection pattern was established. systemic whole-body circulating", "legal_class": null }, { "id": 214, "slug": "resveratrol", "name": "Resveratrol", "aliases": [ "trans-resveratrol", "red-wine polyphenol" ], "type": "Non-peptide", "category": "Longevity & cellular energy", "goals_use_cases": [ "longevity", "cardiovascular", "recovery", "insulin sensitivity", "cognition" ], "delivery_methods": [ "oral", "sublingual" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "resveratrol", "trans-resveratrol", "red-wine polyphenol", "resveratrol peptide", "resveratrol dosage", "Resveratrol dose", "longevity", "cardiovascular", "recovery", "insulin sensitivity", "cognition" ], "feel_search": [ "longevity", "cardiovascular", "recovery", "insulin sensitivity", "cognition" ], "summary": "Resveratrol is a grape-associated plant polyphenol sold as an oral supplement and discussed for longevity.", "search_blob": "resveratrol resveratrol trans-resveratrol red-wine polyphenol resveratrol trans-resveratrol red-wine polyphenol resveratrol peptide resveratrol dosage resveratrol dose longevity cardiovascular recovery insulin sensitivity cognition longevity cardiovascular recovery insulin sensitivity cognition longevity cardiovascular recovery insulin sensitivity cognition resveratrol is a grape-associated plant polyphenol sold as an oral supplement and discussed for longevity. one nmn/tmg/resveratrol user felt no energy benefit and initially felt unwell; the combination prevents isolating resveratrol. resveratrol is an oral compound people look up for longevity. discussed for aging markers, energy, or recovery more than acute gym pumps. longevity & cellular energy non-peptide systemic systemic oral polyphenol (bioavailability-limited). systemic whole-body circulating", "legal_class": null }, { "id": 215, "slug": "tadalafil", "name": "Tadalafil", "aliases": [ "Cialis", "Cialis Daily", "the weekend pill", "generic Cialis", "Adcirca (PAH brand, 20 mg tablet / 40 mg daily talk)", "Alyq (PAH generic brand talk)", "Tadalafil citrate (forum chemistry shorthand \u2014 commercial salt is not always specified)", "Daily Cialis / daily tad", "Tad / tada (forum shorthand)" ], "type": "Non-peptide", "category": "Sexual / reproductive", "goals_use_cases": [ "libido", "performance", "TRT-adjacent sexual function", "libido / erectile function (discussed)", "morning wood / spontaneous erection quality (community)", "BPH / urinary flow (labeled daily-use talk)", "gym pumps / vascularity (community)", "blood-pressure / endothelial talk (community)", "endurance / workout flush (community)", "Peyronie's / post-prostate recovery narratives", "performance continuity", "longevity / endothelial-health halo (biohacker rooms)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "tadalafil", "cialis", "cialas", "cialus", "tadalafill", "tadalafil 5mg", "daily cialis", "weekend pill", "adcirca", "generic cialis", "pumps", "back pain", "back pumps", "morning wood", "stuffy nose", "harder erections", "heartburn" ], "feel_search": [ "pumps", "back pain", "back pumps", "morning wood", "stuffy nose", "weekend pill", "harder erections", "heartburn" ], "summary": "Tadalafil is a long-acting oral PDE5 inhibitor used in medicines for erectile dysfunction, prostate symptoms and pulmonary hypertension.", "search_blob": "tadalafil tadalafil cialis cialis daily the weekend pill generic cialis adcirca (pah brand, 20 mg tablet / 40 mg daily talk) alyq (pah generic brand talk) tadalafil citrate (forum chemistry shorthand \u2014 commercial salt is not always specified) daily cialis / daily tad tad / tada (forum shorthand) tadalafil cialis cialas cialus tadalafill tadalafil 5mg daily cialis weekend pill adcirca generic cialis pumps back pain back pumps morning wood stuffy nose harder erections heartburn libido performance trt-adjacent sexual function libido / erectile function (discussed) morning wood / spontaneous erection quality (community) bph / urinary flow (labeled daily-use talk) gym pumps / vascularity (community) blood-pressure / endothelial talk (community) endurance / workout flush (community) peyronie's / post-prostate recovery narratives performance continuity longevity / endothelial-health halo (biohacker rooms) pumps back pain back pumps morning wood stuffy nose weekend pill harder erections heartburn tadalafil is a long-acting oral pde5 inhibitor used in medicines for erectile dysfunction, prostate symptoms and pulmonary hypertension. one user reported improved erections but worsening back pain that led them to stop; replies describe different tolerability. tadalafil is an oral tablet people look up for erections and gym pumps. novelty often fades even when the vascular effect is still there. back pumps the first week are the story people warn you about. not a hormone. sexual / reproductive non-peptide systemic systemic oral pde5 inhibitor \u2014 whole-body vasodilation with a sexual-function and prostate story in the same threads. systemic whole-body circulating", "legal_class": null }, { "id": 216, "slug": "minoxidil", "name": "Minoxidil", "aliases": [ "Rogaine", "Loniten", "LDOM", "oral minox", "Regaine (UK/EU brand talk)", "Loniten (oral hypertension brand)", "LDOM / low-dose oral minoxidil", "oral minox / OM", "topical minox", "minoxidil 5%", "minoxidil foam", "Kirkland minoxidil (generic foam/liquid talk)" ], "type": "Non-peptide", "category": "Skin, hair & tissue remodeling", "goals_use_cases": [ "skin/hair", "androgenetic alopecia", "androgenetic alopecia / temple and crown (discussed)", "beard fill-in (topical community)", "body-hair / hypertrichosis as a wanted or unwanted effect", "shedding control (after the dread-shed window)", "vasodilator / blood-pressure history (original drug job)", "eyebrow / lash crossover (minority topical)" ], "delivery_methods": [ "topical", "oral" ], "discussion_popularity": "High", "reach": "Mixed", "misspellings_search_terms": [ "minoxidil", "minoxodil", "minox", "rogaine", "regaine", "loniten", "oral minoxidil", "ldom", "minoxidil 5%", "dread shed", "oral vs topical", "switch shed", "puffy face", "palpitations", "beard minox", "body hair", "itchy scalp", "ankle swelling", "baby hairs", "cats minoxidil" ], "feel_search": [ "dread shed", "puffy face", "palpitations", "beard minox", "body hair", "itchy scalp", "ankle swelling", "baby hairs", "oral vs topical", "switch shed", "cats minoxidil" ], "summary": "Minoxidil is a vasodilator used topically or in low-dose oral prescriptions for hair growth; oral and topical effects differ.", "search_blob": "minoxidil minoxidil rogaine loniten ldom oral minox regaine (uk/eu brand talk) loniten (oral hypertension brand) ldom / low-dose oral minoxidil oral minox / om topical minox minoxidil 5% minoxidil foam kirkland minoxidil (generic foam/liquid talk) minoxidil minoxodil minox rogaine regaine loniten oral minoxidil ldom minoxidil 5% dread shed oral vs topical switch shed puffy face palpitations beard minox body hair itchy scalp ankle swelling baby hairs cats minoxidil skin/hair androgenetic alopecia androgenetic alopecia / temple and crown (discussed) beard fill-in (topical community) body-hair / hypertrichosis as a wanted or unwanted effect shedding control (after the dread-shed window) vasodilator / blood-pressure history (original drug job) eyebrow / lash crossover (minority topical) dread shed puffy face palpitations beard minox body hair itchy scalp ankle swelling baby hairs oral vs topical switch shed cats minoxidil minoxidil is a vasodilator used topically or in low-dose oral prescriptions for hair growth; oral and topical effects differ. topical users may notice scalp irritation; oral users may feel nothing or report puffiness or a faster pulse. an early shed can precede visible changes over months. minoxidil is a topical and oral drug people look up for hair. first \u201cmaybe this is doing something\u201d window in photo logs \u2014 baby hairs, less daily shed. 2.5 mg oral is the male copy-paste. puffy face and extra body hair are the sides people actually argue about. skin, hair & tissue remodeling non-peptide mixed mixed \u2014 foam/liquid is scalp-local; oral low-dose is whole-body with hair as the wanted side. mixed local systemic", "legal_class": null }, { "id": 217, "slug": "dutasteride", "name": "Dutasteride", "aliases": [ "Avodart", "dut", "dut 0.5", "dual 5-AR inhibitor", "Jalyn (dutasteride + tamsulosin combo talk)", "Avolve / Zyfotir (regional brand talk)" ], "type": "Non-peptide", "category": "Skin, hair & tissue remodeling", "goals_use_cases": [ "skin/hair", "androgenetic alopecia", "BPH", "androgenetic alopecia / DHT blockade (off-label US)", "BPH / urinary (labeled 0.5 mg)", "finasteride non-responder step-up", "shedding control (after the switch shed)", "TRT-adjacent DHT talk (minority, contested)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "dutasteride", "dutasteride 0.5", "avodart", "avodart hair", "dutasterid", "dutas", "dual 5ar", "dut vs fin", "mesotherapy", "2x week dut", "3x week dut", "topical dut", "allopregnanolone", "watery semen", "no libido", "switch shed", "brain fog", "nipple sensitivity", "morning wood gone", "2x week", "3x week" ], "feel_search": [ "watery semen", "no libido", "switch shed", "dut vs fin", "brain fog", "nipple sensitivity", "morning wood gone", "mesotherapy", "2x week", "3x week", "allopregnanolone", "topical dut" ], "summary": "Dutasteride (Avodart) blocks both main 5-alpha-reductase types, reducing DHT; it is used for prostate enlargement and discussed for hair loss.", "search_blob": "dutasteride dutasteride avodart dut dut 0.5 dual 5-ar inhibitor jalyn (dutasteride + tamsulosin combo talk) avolve / zyfotir (regional brand talk) dutasteride dutasteride 0.5 avodart avodart hair dutasterid dutas dual 5ar dut vs fin mesotherapy 2x week dut 3x week dut topical dut allopregnanolone watery semen no libido switch shed brain fog nipple sensitivity morning wood gone 2x week 3x week skin/hair androgenetic alopecia bph androgenetic alopecia / dht blockade (off-label us) bph / urinary (labeled 0.5 mg) finasteride non-responder step-up shedding control (after the switch shed) trt-adjacent dht talk (minority, contested) watery semen no libido switch shed dut vs fin brain fog nipple sensitivity morning wood gone mesotherapy 2x week 3x week allopregnanolone topical dut dutasteride (avodart) blocks both main 5-alpha-reductase types, reducing dht; it is used for prostate enlargement and discussed for hair loss. a switch-from-finasteride account describes many months of shedding before possible new hairs. oral and topical minoxidil plus microneedling complicate the result. dutasteride is an oral compound people look up for hair. fin held me, dut grew me. half-life is about five weeks. sides, if they show, do not vanish on monday. skin, hair & tissue remodeling non-peptide systemic systemic oral dual 5-alpha-reductase inhibitor \u2014 serum and scalp dht both fall hard. systemic whole-body circulating", "legal_class": null }, { "id": 218, "slug": "anastrozole", "name": "Anastrozole", "aliases": [ "Arimidex", "Adex", "aromatase inhibitor", "AI / aromatase inhibitor (when they mean this one)", "anastrozole 1 mg", "Arimidex microdose" ], "type": "Non-peptide", "category": "Hormone modulators", "goals_use_cases": [ "hormone axis", "estradiol control", "estradiol control on TRT / AAS (discussed)", "nipple sensitivity / gyno scare (community)", "water retention / bloat (high-E2 talk)", "libido (both high-E2 and crashed-E2 stories)", "fertility / T:E2 ratio (clinic-adjacent)", "breast-cancer label (1 mg daily in women \u2014 not the TRT card)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "anastrozole", "anastrazole", "arimidex", "arimidex 0.25", "adex", "aromatase inhibitor", "crashed e2", "high e2 trt", "low shbg", "0.125 anastrozole", "as needed ai", "sensitive e2", "dry joints", "no libido", "nipple sensitivity", "water retention", "high e2", "mood crash", "no morning wood", "0.125" ], "feel_search": [ "crashed e2", "dry joints", "no libido", "nipple sensitivity", "water retention", "high e2", "mood crash", "no morning wood", "low shbg", "as needed ai", "sensitive e2", "0.125" ], "summary": "Anastrozole (Arimidex) is an oral aromatase inhibitor that reduces production of estradiol from androgens.", "search_blob": "anastrozole anastrozole arimidex adex aromatase inhibitor ai / aromatase inhibitor (when they mean this one) anastrozole 1 mg arimidex microdose anastrozole anastrazole arimidex arimidex 0.25 adex aromatase inhibitor crashed e2 high e2 trt low shbg 0.125 anastrozole as needed ai sensitive e2 dry joints no libido nipple sensitivity water retention high e2 mood crash no morning wood 0.125 hormone axis estradiol control estradiol control on trt / aas (discussed) nipple sensitivity / gyno scare (community) water retention / bloat (high-e2 talk) libido (both high-e2 and crashed-e2 stories) fertility / t:e2 ratio (clinic-adjacent) breast-cancer label (1 mg daily in women \u2014 not the trt card) crashed e2 dry joints no libido nipple sensitivity water retention high e2 mood crash no morning wood low shbg as needed ai sensitive e2 0.125 anastrozole (arimidex) is an oral aromatase inhibitor that reduces production of estradiol from androgens. a trt account describes brief initial symptom improvement followed by a delayed low-estrogen-like slump. symptoms alone did not reliably identify the hormone problem. anastrozole is an oral aromatase inhibitor people look up for estradiol. stops some testosterone from becoming estradiol. accounts describe adverse symptoms even after 0.25 mg. dry joints and low libido are reported, but those feelings alone do not establish that estradiol was driven too low. hormone modulators non-peptide systemic systemic oral non-steroidal aromatase inhibitor \u2014 whole-body estradiol production drops. systemic whole-body circulating", "legal_class": null }, { "id": 219, "slug": "melatonin", "name": "Melatonin", "aliases": [ "melatonin gummy", "microdose melatonin", "injectable melatonin", "N-acetyl-5-methoxytryptamine", "circadian hormone", "time-release melatonin / Circadin-class (2 mg PR talk)", "injectable melatonin (research-chem / marketplace vials)", "microdose melatonin (0.3 mg talk)" ], "type": "Non-peptide", "category": "Sleep / mood", "goals_use_cases": [ "sleep", "jet lag", "sleep onset / jet lag (discussed)", "vivid dreams / REM talk", "circadian shift (night-owl / shift-work)", "recovery / next-day grogginess (the downside people chase away)", "high-dose antioxidant / immune halo (community, thinner)", "stack with DSIP / apigenin / magnesium (Huberman-adjacent)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "melatonin", "melatonine", "melatonin 0.3", "melatonin 10mg", "melatonin gummy", "injectable melatonin", "huberman melatonin", "groggy", "vivid dreams", "hangover", "jet lag", "3am wake", "head movies", "can't fall asleep" ], "feel_search": [ "groggy", "vivid dreams", "hangover", "jet lag", "3am wake", "head movies", "can't fall asleep" ], "summary": "Melatonin is a hormone that signals biological night, sold in sleep supplements and used for body-clock timing rather than guaranteed sedation.", "search_blob": "melatonin melatonin melatonin gummy microdose melatonin injectable melatonin n-acetyl-5-methoxytryptamine circadian hormone time-release melatonin / circadin-class (2 mg pr talk) injectable melatonin (research-chem / marketplace vials) microdose melatonin (0.3 mg talk) melatonin melatonine melatonin 0.3 melatonin 10mg melatonin gummy injectable melatonin huberman melatonin groggy vivid dreams hangover jet lag 3am wake head movies can't fall asleep sleep jet lag sleep onset / jet lag (discussed) vivid dreams / rem talk circadian shift (night-owl / shift-work) recovery / next-day grogginess (the downside people chase away) high-dose antioxidant / immune halo (community, thinner) stack with dsip / apigenin / magnesium (huberman-adjacent) groggy vivid dreams hangover jet lag 3am wake head movies can't fall asleep melatonin is a hormone that signals biological night, sold in sleep supplements and used for body-clock timing rather than guaranteed sedation. it may help sleep without producing a strong sleepy feeling. in the reviewed thread, one person slept better with sleep-habit changes, while others reported next-day grogginess or early awakening. melatonin is an oral compound people look up for sleep. sleepy, slightly heavy eyes if it is going to work. injectable 10 mg vials exist on peptide shops. almost all the real talk is still oral. sleep / mood non-peptide systemic systemic \u2014 pineal hormone (an indoleamine, not a peptide). systemic whole-body circulating", "legal_class": null }, { "id": 220, "slug": "teriparatide", "name": "Teriparatide", "aliases": [ "Forteo", "PTH 1-34", "Forsteo (EU brand talk)", "recombinant PTH(1-34)", "generic teriparatide / Teva pen", "Bonsity (follow-on teriparatide talk)" ], "type": "Peptide", "category": "Growth factors", "goals_use_cases": [ "bone density", "longevity", "bone density / osteoporosis (labeled)", "fracture-risk talk (high-risk spine)", "anabolic bone build then antiresorptive lock-in", "longevity / Huberman 75+ bone-peptide teaser", "glucocorticoid or very-low-T-score rescue narratives", "post-Forteo \u201cwhat do I take next\u201d (Prolia / Reclast / alendronate)" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "teriparatide", "teraparatide", "forteo", "forsteo", "pth 1-34", "forteo pen", "bone peptide", "bone pain", "nausea after pin", "lightheaded", "fridge pen", "next dexa", "osteosarcoma" ], "feel_search": [ "bone pain", "nausea after pin", "lightheaded", "fridge pen", "next dexa", "osteosarcoma" ], "summary": "Teriparatide is PTH(1-34), a daily osteoporosis medicine that briefly stimulates bone formation. A short daily PTH spike tells osteoblasts to lay bone.", "search_blob": "teriparatide teriparatide forteo pth 1-34 forsteo (eu brand talk) recombinant pth(1-34) generic teriparatide / teva pen bonsity (follow-on teriparatide talk) teriparatide teraparatide forteo forsteo pth 1-34 forteo pen bone peptide bone pain nausea after pin lightheaded fridge pen next dexa osteosarcoma bone density longevity bone density / osteoporosis (labeled) fracture-risk talk (high-risk spine) anabolic bone build then antiresorptive lock-in longevity / huberman 75+ bone-peptide teaser glucocorticoid or very-low-t-score rescue narratives post-forteo \u201cwhat do i take next\u201d (prolia / reclast / alendronate) bone pain nausea after pin lightheaded fridge pen next dexa osteosarcoma teriparatide is pth(1-34), a daily osteoporosis medicine that briefly stimulates bone formation. a short daily pth spike tells osteoblasts to lay bone. some osteoporosis patients reported feeling little different, while one described headaches early in treatment; bone response is assessed separately. teriparatide is pth(1-34), a daily osteoporosis medicine that briefly stimulates bone formation. a short daily pth spike tells osteoblasts to lay bone. first months can feel like bone pain and nausea. not a gym peptide. growth factors peptide systemic systemic daily pth(1-34) pulse aimed at bone formation. systemic whole-body circulating", "legal_class": null }, { "id": 221, "slug": "abaloparatide", "name": "Abaloparatide", "aliases": [ "Tymlos", "PTHrP analog", "BA058 (development code talk)", "abaloparatide 80 mcg" ], "type": "Peptide", "category": "Growth factors", "goals_use_cases": [ "bone density", "bone density / osteoporosis (labeled)", "spine T-score talk", "Forteo alternative (room-temp pen, side-effect shop)", "Huberman-class bone-peptide search", "post-course antiresorptive lock-in" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "abaloparatide", "aloparatide", "tymlos", "tylos", "pthrp", "tymlos 80", "injection sting", "dizzy after shot", "hair shedding", "room temperature pen", "tymlos vs forteo" ], "feel_search": [ "injection sting", "dizzy after shot", "hair shedding", "room temperature pen", "tymlos vs forteo" ], "summary": "Tymlos is a daily bone-building medicine people discuss for osteoporosis. Hits the PTH1 receptor with a short daily pulse so osteoblasts build.", "search_blob": "abaloparatide abaloparatide tymlos pthrp analog ba058 (development code talk) abaloparatide 80 mcg abaloparatide aloparatide tymlos tylos pthrp tymlos 80 injection sting dizzy after shot hair shedding room temperature pen tymlos vs forteo bone density bone density / osteoporosis (labeled) spine t-score talk forteo alternative (room-temp pen, side-effect shop) huberman-class bone-peptide search post-course antiresorptive lock-in injection sting dizzy after shot hair shedding room temperature pen tymlos vs forteo tymlos is a daily bone-building medicine people discuss for osteoporosis. hits the pth1 receptor with a short daily pulse so osteoblasts build. some patients describe a brief racing heart or headache after injections. bone-density improvement is a longer-term outcome rather than a same-day sensation. tymlos is a daily bone-building medicine people discuss for osteoporosis. hits the pth1 receptor with a short daily pulse so osteoblasts build. people pick it over forteo for travel and a slightly quieter side-effect story. growth factors peptide systemic systemic daily pthrp-analog pulse for bone formation. systemic whole-body circulating", "legal_class": null }, { "id": 222, "slug": "follitropin-alfa", "name": "rFSH (Follitropin alfa)", "aliases": [ "Gonal-F", "recombinant FSH", "follitropin alfa", "Gonal-f RFF / Gonal-f pen", "Follistim / follitropin beta (sister product, not identical)", "Puregon (beta, regional)", "Foligraf (regional rFSH kit talk)" ], "type": "Peptide", "category": "Sexual / reproductive", "goals_use_cases": [ "fertility", "hormone support", "fertility / spermatogenesis on or after TRT", "testicular volume (with hCG)", "hypogonadotropic hypogonadism (labeled male use)", "IVF / ovulation induction (labeled female use \u2014 different IU world)", "Tatem-style \u201cFSH + hCG if you want kids on TRT\u201d" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "rfsh", "r-fsh", "gonal-f", "gonal f", "follitropin", "follitropin alfa", "follistim", "puregon", "gonal", "zero sperm", "azoospermia", "testicular volume", "want kids on trt" ], "feel_search": [ "zero sperm", "azoospermia", "testicular volume", "gonal", "want kids on trt" ], "summary": "Follitropin alfa is manufactured FSH, the fertility hormone in Gonal-F; men discuss it when sperm production remains low despite hCG.", "search_blob": "rfsh (follitropin alfa) follitropin-alfa gonal-f recombinant fsh follitropin alfa gonal-f rff / gonal-f pen follistim / follitropin beta (sister product, not identical) puregon (beta, regional) foligraf (regional rfsh kit talk) rfsh r-fsh gonal-f gonal f follitropin follitropin alfa follistim puregon gonal zero sperm azoospermia testicular volume want kids on trt fertility hormone support fertility / spermatogenesis on or after trt testicular volume (with hcg) hypogonadotropic hypogonadism (labeled male use) ivf / ovulation induction (labeled female use \u2014 different iu world) tatem-style \u201cfsh + hcg if you want kids on trt\u201d zero sperm azoospermia testicular volume gonal want kids on trt follitropin alfa is manufactured fsh, the fertility hormone in gonal-f; men discuss it when sperm production remains low despite hcg. usually there is no distinctive immediate benefit to feel; injection soreness or bruising may be noticeable. male fertility response is followed with semen testing over months. rfsh (follitropin alfa) is a peptide people look up for fertility. labeled with hcg for spermatogenesis in hypogonadotropic men. 75\u2013150 iu a few times a week in those logs. months, not weeks. not hmg. sexual / reproductive peptide systemic systemic glycoprotein hormone (recombinant fsh). systemic whole-body circulating", "legal_class": null }, { "id": 223, "slug": "eloralintide", "name": "Eloralintide", "aliases": [ "LY3841136", "Elo", "Elo / Elora (forum shorthand)", "Lilly selective amylin", "SARA (selective amylin receptor agonist talk)" ], "type": "Peptide", "category": "Metabolic / GLP-1 class", "goals_use_cases": [ "fat loss", "appetite control", "fat loss / obesity (Phase 2)", "appetite / amylin satiety (less GLP-nausea story)", "add-on to tirzepatide (Phase 1b combo talk)", "cagrilintide / CagriSema comparison", "gray-vial \u201cnext after reta\u201d shopping" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "eloralintide", "ly3841136", "elora", "elo peptide", "lilly amylin", "amylin nausea", "less vomit than glp", "elo vial", "cagrisema alternative" ], "feel_search": [ "amylin nausea", "less vomit than glp", "elo vial", "cagrisema alternative" ], "summary": "Eloralintide (LY3841136) is an investigational long-acting selective amylin agonist studied as a weekly injection for weight management.", "search_blob": "eloralintide eloralintide ly3841136 elo elo / elora (forum shorthand) lilly selective amylin sara (selective amylin receptor agonist talk) eloralintide ly3841136 elora elo peptide lilly amylin amylin nausea less vomit than glp elo vial cagrisema alternative fat loss appetite control fat loss / obesity (phase 2) appetite / amylin satiety (less glp-nausea story) add-on to tirzepatide (phase 1b combo talk) cagrilintide / cagrisema comparison gray-vial \u201cnext after reta\u201d shopping amylin nausea less vomit than glp elo vial cagrisema alternative eloralintide (ly3841136) is an investigational long-acting selective amylin agonist studied as a weekly injection for weight management. a gray-market account describes delayed nausea; a separate blinded trial participant reports less food preoccupation. unknown products or treatment arms limit both accounts. eloralintide is a peptide people look up for fat loss. decreased appetite, some bloating, not a stimulant. how-it-feels logs are still thin. nausea week 1 is the n=1 chorus. metabolic / glp-1 class peptide systemic systemic once-weekly selective amylin receptor agonist. systemic whole-body circulating", "legal_class": null }, { "id": 224, "slug": "petrelintide", "name": "Petrelintide", "aliases": [ "ZP8396", "Zealand amylin", "Roche / Zealand amylin analog", "pertrelintide (common misspelling in press)" ], "type": "Peptide", "category": "Metabolic / GLP-1 class", "goals_use_cases": [ "fat loss", "fat loss / obesity (Phase 2)", "\u201cGLP nausea-lite\u201d amylin story", "future combo with enicepatide / CT-388 (Roche talk)", "cagrilintide / eloralintide comparison" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "petrelintide", "pertrelintide", "zp8396", "zealand amylin", "roche amylin", "placebo like gi", "amylin without vomit", "zupreme", "10 percent but stay on it" ], "feel_search": [ "placebo like gi", "amylin without vomit", "zupreme", "10 percent but stay on it" ], "summary": "Petrelintide (ZP8396) is an investigational long-acting amylin analogue studied for weight management.", "search_blob": "petrelintide petrelintide zp8396 zealand amylin roche / zealand amylin analog pertrelintide (common misspelling in press) petrelintide pertrelintide zp8396 zealand amylin roche amylin placebo like gi amylin without vomit zupreme 10 percent but stay on it fat loss fat loss / obesity (phase 2) \u201cglp nausea-lite\u201d amylin story future combo with enicepatide / ct-388 (roche talk) cagrilintide / eloralintide comparison placebo like gi amylin without vomit zupreme 10 percent but stay on it petrelintide (zp8396) is an investigational long-acting amylin analogue studied for weight management. the inspected discussion compares trial results and tolerability hopes; it does not provide a petrelintide user's felt timeline. petrelintide is a research compound people look up for fat loss. pitched as weight loss with a glp-like job and a quieter stomach. almost no real-world pin diaries yet. the talk is the gi table. metabolic / glp-1 class peptide systemic systemic once-weekly long-acting amylin analog (zealand, partnered with roche). systemic whole-body circulating", "legal_class": null }, { "id": 225, "slug": "enicepatide", "name": "Enicepatide", "aliases": [ "CT-388", "RO7795068", "CT388", "RG6640", "Roche / Carmot dual GLP-1/GIP" ], "type": "Peptide", "category": "Metabolic / GLP-1 class", "goals_use_cases": [ "fat loss", "fat loss / obesity (Phase 2 ~23%)", "tirzepatide-class dual agonist comparison", "planned combo with petrelintide", "T2D obesity (separate Phase 2)" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "enicepatide", "encipetide", "ct-388", "ct388", "ro7795068", "carmot dual", "another tirz", "roche dual", "food noise" ], "feel_search": [ "another tirz", "ct-388", "roche dual", "food noise" ], "summary": "Enicepatide (CT-388) is an investigational dual GLP-1/GIP peptide injection being studied for weight management.", "search_blob": "enicepatide enicepatide ct-388 ro7795068 ct388 rg6640 roche / carmot dual glp-1/gip enicepatide encipetide ct-388 ct388 ro7795068 carmot dual another tirz roche dual food noise fat loss fat loss / obesity (phase 2 ~23%) tirzepatide-class dual agonist comparison planned combo with petrelintide t2d obesity (separate phase 2) another tirz ct-388 roche dual food noise enicepatide (ct-388) is an investigational dual glp-1/gip peptide injection being studied for weight management. the inspected post is a request to meet trial participants. it contains no substantive use report, so it cannot supply a personal appetite or side-effect timeline. enicepatide is a peptide people look up for fat loss. dual incretin \u2014 satiety, slower stomach, glucose-dependent insulin. almost no real pin diaries. the talk is the ada slide. metabolic / glp-1 class peptide systemic systemic once-weekly biased dual glp-1/gip agonist (carmot \u2192 roche). systemic whole-body circulating", "legal_class": null }, { "id": 226, "slug": "aleniglipron", "name": "Aleniglipron", "aliases": [ "GSBR-1290", "Structure Therapeutics oral GLP-1", "aleniglipron pill" ], "type": "Non-peptide", "category": "Metabolic / GLP-1 class", "goals_use_cases": [ "fat loss", "appetite control", "fat loss without a pin", "orforglipron comparison (the other oral small-molecule GLP-1)", "needle-averse GLP-1 access talk", "Phase 3 2H 2026 watch" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "aleniglipron", "gsbr-1290", "gsbr1290", "structure oral glp", "oral glp vomit", "pill not rybelsus", "orforglipron alternative" ], "feel_search": [ "oral glp vomit", "pill not rybelsus", "orforglipron alternative" ], "summary": "Aleniglipron (GSBR-1290) is an investigational non-peptide GLP-1 tablet being developed for weight management.", "search_blob": "aleniglipron aleniglipron gsbr-1290 structure therapeutics oral glp-1 aleniglipron pill aleniglipron gsbr-1290 gsbr1290 structure oral glp oral glp vomit pill not rybelsus orforglipron alternative fat loss appetite control fat loss without a pin orforglipron comparison (the other oral small-molecule glp-1) needle-averse glp-1 access talk phase 3 2h 2026 watch oral glp vomit pill not rybelsus orforglipron alternative aleniglipron (gsbr-1290) is an investigational non-peptide glp-1 tablet being developed for weight management. the inspected community thread discusses a future oral option, not firsthand use. appetite and nausea timelines should come from its trials, not other glp-1 drugs. aleniglipron is an oral compound for fat loss. satiety, slower gastric emptying and glucose effects are the class rationale; this investigational program uses oral tablets. later 2.5 mg starting cohorts are a tolerability discussion, not a personal dose lesson; phase 3 is underway, not approval. metabolic / glp-1 class non-peptide systemic systemic once-daily oral small-molecule glp-1 agonist. systemic whole-body circulating", "legal_class": null }, { "id": 227, "slug": "ribupatide", "name": "Ribupatide", "aliases": [ "HRS-9531", "KAI-9531", "HRS9531", "Kailera / Hengrui dual GLP-1/GIP", "ribupatide oral", "ribupatide injection" ], "type": "Peptide", "category": "Metabolic / GLP-1 class", "goals_use_cases": [ "fat loss", "fat loss / obesity (China Phase 3 + global Phase 3)", "tirzepatide-class dual comparison", "oral dual-agonist curiosity", "gray \u201cChina tirz\u201d shopping (identity risk)" ], "delivery_methods": [ "subcutaneous", "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "ribupatide", "hrs-9531", "hrs9531", "kai-9531", "kailera", "hengrui dual", "china tirz", "oral dual" ], "feel_search": [ "china tirz", "hrs9531", "kailera", "oral dual" ], "summary": "Ribupatide (HRS-9531/KAI-9531) is an investigational dual-receptor agonist for weight management, developed in injectable and oral forms.", "search_blob": "ribupatide ribupatide hrs-9531 kai-9531 hrs9531 kailera / hengrui dual glp-1/gip ribupatide oral ribupatide injection ribupatide hrs-9531 hrs9531 kai-9531 kailera hengrui dual china tirz oral dual fat loss fat loss / obesity (china phase 3 + global phase 3) tirzepatide-class dual comparison oral dual-agonist curiosity gray \u201cchina tirz\u201d shopping (identity risk) china tirz hrs9531 kailera oral dual ribupatide (hrs-9531/kai-9531) is an investigational dual-receptor agonist for weight management, developed in injectable and oral forms. a trial participant later said they felt good, but their blinded assignment did not establish that they received ribupatide. ribupatide is a peptide people look up for fat loss. import tirz food-noise talk until there is a real english logbook. big phase 3 still out. vial labels are not that trial. metabolic / glp-1 class peptide systemic systemic dual glp-1/gip \u2014 weekly injection (kainetic / china phase 3) and a separate once-daily oral program. systemic whole-body circulating", "legal_class": null }, { "id": 228, "slug": "berobenatide", "name": "Berobenatide", "aliases": [ "MET-097i", "Pfizer monthly GLP-1", "PF-08653944", "PF\u20193944", "MET-097i (Metsera name before Pfizer)" ], "type": "Peptide", "category": "Metabolic / GLP-1 class", "goals_use_cases": [ "fat loss", "fat loss / obesity", "monthly instead of weekly GLP-1 talk", "Pfizer obesity comeback after danuglipron" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "berobenatide", "met-097i", "met097", "pfizer monthly glp", "pf3944", "monthly shot", "one injection a month", "vesper", "pfizer glp" ], "feel_search": [ "monthly shot", "one injection a month", "vesper", "pfizer glp" ], "summary": "Berobenatide (MET-097i) is an investigational long-acting GLP-1 peptide studied in weekly and monthly injection programs.", "search_blob": "berobenatide berobenatide met-097i pfizer monthly glp-1 pf-08653944 pf\u20193944 met-097i (metsera name before pfizer) berobenatide met-097i met097 pfizer monthly glp pf3944 monthly shot one injection a month vesper pfizer glp fat loss fat loss / obesity monthly instead of weekly glp-1 talk pfizer obesity comeback after danuglipron monthly shot one injection a month vesper pfizer glp berobenatide (met-097i) is an investigational long-acting glp-1 peptide studied in weekly and monthly injection programs. a relayed blinded-trial account describes less food noise, early fullness and occasional heartburn over five weeks. the participant did not know their treatment assignment. berobenatide is a peptide people look up for fat loss. monthly maintenance is the only reason this name beats a dozen other glp-1s in 2026 chats. no real-world monthly diary yet. just the ada table. metabolic / glp-1 class peptide systemic systemic ultra-long glp-1 peptide \u2014 weekly titration then monthly maintenance in vesper. systemic whole-body circulating", "legal_class": null }, { "id": 229, "slug": "pyrilutamide", "name": "Pyrilutamide", "aliases": [ "KX-826", "KX826", "Kintor topical AR antagonist", "pyrilutamide 0.5%", "pyrilutamide 1%" ], "type": "Non-peptide", "category": "Skin, hair & tissue remodeling", "goals_use_cases": [ "skin/hair", "androgenetic alopecia / topical anti-androgen", "fin/dut side-effect escape", "RU-58841 comparison", "shed control / itch (community)", "add-on to minoxidil" ], "delivery_methods": [ "topical" ], "discussion_popularity": "Medium", "reach": "Local", "misspellings_search_terms": [ "pyrilutamide", "pyrilutimide", "kx-826", "kx826", "kintor", "kx 826", "scalp itch gone", "kx shed", "nipple sensitivity", "better than ru", "topical antiandrogen" ], "feel_search": [ "scalp itch gone", "kx shed", "nipple sensitivity", "better than ru", "topical antiandrogen" ], "summary": "Pyrilutamide (KX-826) is a topical androgen-receptor blocker studied for hair loss.", "search_blob": "pyrilutamide pyrilutamide kx-826 kx826 kintor topical ar antagonist pyrilutamide 0.5% pyrilutamide 1% pyrilutamide pyrilutimide kx-826 kx826 kintor kx 826 scalp itch gone kx shed nipple sensitivity better than ru topical antiandrogen skin/hair androgenetic alopecia / topical anti-androgen fin/dut side-effect escape ru-58841 comparison shed control / itch (community) add-on to minoxidil scalp itch gone kx shed nipple sensitivity better than ru topical antiandrogen pyrilutamide (kx-826) is a topical androgen-receptor blocker studied for hair loss. hair reports range from regrowth after shedding to no visible change; continued minoxidil and uncertain products complicate comparisons. pyrilutamide is an oral compound people look up for skin. \u201calmost instantly stops my scalp itch and cuts shedding\u201d \u2014 a 5-month photo thread. phase 3 grew ~10 extra hairs/cm\u00b2 over placebo. a few people still get nipple/libido sides. skin, hair & tissue remodeling non-peptide local topical androgen-receptor blocker aimed at the follicle. local site pin topical", "legal_class": null }, { "id": 230, "slug": "finasteride", "name": "Finasteride", "aliases": [ "Propecia", "Proscar", "fin 1mg", "fin", "type-2 5-AR inhibitor", "topical finasteride", "finasteride 0.25%", "Hims / Keeps fin", "compounded topical fin", "PFS" ], "type": "Non-peptide", "category": "Skin, hair & tissue remodeling", "goals_use_cases": [ "skin/hair", "androgenetic alopecia / DHT blockade", "BPH / urinary (labeled 5 mg)", "shed control after the first dump", "dutasteride comparison", "topical vs oral 5-AR talk" ], "delivery_methods": [ "oral", "topical" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "finasteride", "propecia", "proscar", "finasterid", "finasteride 1mg", "topical fin", "fin sides", "pfs", "second shed", "topical fin sides", "hair shed", "watery semen", "libido crash", "dht", "hairline", "every other day fin" ], "feel_search": [ "hair shed", "pfs", "watery semen", "libido crash", "propecia", "dht", "hairline", "every other day fin", "second shed", "topical fin sides", "watery semen", "pfs" ], "summary": "Finasteride inhibits type-2 5-alpha-reductase to lower DHT; tablets are used for male-pattern hair loss and prostate enlargement.", "search_blob": "finasteride finasteride propecia proscar fin 1mg fin type-2 5-ar inhibitor topical finasteride finasteride 0.25% hims / keeps fin compounded topical fin pfs finasteride propecia proscar finasterid finasteride 1mg topical fin fin sides pfs second shed topical fin sides hair shed watery semen libido crash dht hairline every other day fin skin/hair androgenetic alopecia / dht blockade bph / urinary (labeled 5 mg) shed control after the first dump dutasteride comparison topical vs oral 5-ar talk hair shed pfs watery semen libido crash propecia dht hairline every other day fin second shed topical fin sides watery semen pfs finasteride inhibits type-2 5-alpha-reductase to lower dht; tablets are used for male-pattern hair loss and prostate enlargement. a 4.5-year user describes gradual stabilization over months and ongoing shedding waves despite maintained density. they report no sexual symptoms but mild breast enlargement. finasteride is an oral drug people look up for hair. density change is slow; vertex often shows before hairline. month-2 shed is the tax. dut is the step-up, not the same drug. skin, hair & tissue remodeling non-peptide systemic systemic oral type-2 5-alpha-reductase inhibitor at 1 mg; topical solutions try to keep it on the scalp. systemic whole-body circulating", "legal_class": null }, { "id": 231, "slug": "seltorexant", "name": "Seltorexant", "aliases": [ "JNJ-42847922", "MIN-202", "2-SORA", "selective OX2 antagonist", "seltorexant 20 mg" ], "type": "Non-peptide", "category": "Sleep / mood", "goals_use_cases": [ "sleep", "sleep onset / staying asleep", "depression-with-insomnia trial talk", "DSIP comparison", "orexin / DORA comparison", "wearable sleep-score n=1s" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "seltorexant", "seltorexent", "jnj-42847922", "min-202", "ox2 antagonist", "seltorexant 5mg", "seltorexant 20mg", "kimera seltorexant", "dayvigo vs seltorexant", "oura seltorexant", "2-sora", "wired but tired", "micro awakenings", "sleep efficiency", "groggy", "orexin", "better than dsip", "lights out", "kimera", "oura", "whoop", "dayvigo" ], "feel_search": [ "wired but tired", "micro awakenings", "sleep efficiency", "groggy", "orexin", "better than dsip", "lights out", "kimera", "oura", "whoop", "dayvigo", "2-sora" ], "summary": "Seltorexant (JNJ-42847922/MIN-202) is an investigational oral orexin-2 receptor blocker studied for sleep-related problems.", "search_blob": "seltorexant seltorexant jnj-42847922 min-202 2-sora selective ox2 antagonist seltorexant 20 mg seltorexant seltorexent jnj-42847922 min-202 ox2 antagonist seltorexant 5mg seltorexant 20mg kimera seltorexant dayvigo vs seltorexant oura seltorexant 2-sora wired but tired micro awakenings sleep efficiency groggy orexin better than dsip lights out kimera oura whoop dayvigo sleep sleep onset / staying asleep depression-with-insomnia trial talk dsip comparison orexin / dora comparison wearable sleep-score n=1s wired but tired micro awakenings sleep efficiency groggy orexin better than dsip lights out kimera oura whoop dayvigo 2-sora seltorexant (jnj-42847922/min-202) is an investigational oral orexin-2 receptor blocker studied for sleep-related problems. some users describe easier sleep onset, while others say it does little for restless sleep or early awakening. seltorexant is an oral compound people look up for sleep. actual forum reports range from strong sleep-onset benefit to little effect or weak sleep maintenance. not dsip. not ambien. short half-life. still not an approved insomnia pill in these threads. sleep / mood non-peptide systemic systemic oral selective ox2 (orexin-2) blocker. systemic whole-body circulating", "legal_class": null }, { "id": 232, "slug": "tudca", "name": "TUDCA", "aliases": [ "tauroursodeoxycholic acid", "tauroursodeoxycholate", "TUDCA 500", "bile acid supplement", "UDCA taurine conjugate" ], "type": "Non-peptide", "category": "Gut & inflammation peptides", "goals_use_cases": [ "gut health", "liver enzymes / \u201con-cycle\u201d liver talk", "bile flow / fatty-meal digestion", "gallbladder-out digestion", "ER-stress / mitochondria halo", "SIBO / bloating experiments", "NAC stack companion" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "tudca", "tudka", "tauroursodeoxycholic", "tudca 500", "tudca 1000", "bile acid", "liver support", "udca", "ursodiol", "gallstones", "glp liver", "bile diarrhea", "right upper pain", "liver enzymes", "on cycle liver", "bloating after fats", "gallbladder", "ox bile", "bile stasis" ], "feel_search": [ "bile diarrhea", "right upper pain", "liver enzymes", "on cycle liver", "bloating after fats", "gallbladder", "ox bile", "gallstones", "glp liver", "bile stasis" ], "summary": "TUDCA is tauroursodeoxycholic acid, an orally supplemented bile acid discussed for liver and digestive concerns.", "search_blob": "tudca tudca tauroursodeoxycholic acid tauroursodeoxycholate tudca 500 bile acid supplement udca taurine conjugate tudca tudka tauroursodeoxycholic tudca 500 tudca 1000 bile acid liver support udca ursodiol gallstones glp liver bile diarrhea right upper pain liver enzymes on cycle liver bloating after fats gallbladder ox bile bile stasis gut health liver enzymes / \u201con-cycle\u201d liver talk bile flow / fatty-meal digestion gallbladder-out digestion er-stress / mitochondria halo sibo / bloating experiments nac stack companion bile diarrhea right upper pain liver enzymes on cycle liver bloating after fats gallbladder ox bile gallstones glp liver bile stasis tudca is tauroursodeoxycholic acid, an orally supplemented bile acid discussed for liver and digestive concerns. accounts include easier digestion or less gallbladder pain, alongside frequent bowel movements, disturbed sleep and other adverse experiences. tudca is an oral compound for recovery. some users described easier gallbladder pain or digestion, while others described insomnia, hypoglycemic episodes or severe reflux. not nac. not ox bile. diarrhea means you overshot, not that it\u2019s \u201cworking.\u201d gut & inflammation peptides non-peptide systemic systemic oral bile acid (taurine-conjugated udca). systemic whole-body circulating", "legal_class": null }, { "id": 233, "slug": "ptd-dbm", "name": "PTD-DBM", "aliases": [ "PTD DBM", "Wnt hair peptide", "PTD-DBM peptide", "protein transduction domain\u2013Dishevelled binding motif", "CXXC5-Dvl disrupting peptide" ], "type": "Peptide", "category": "Skin, hair & tissue remodeling", "goals_use_cases": [ "skin/hair", "androgenetic alopecia / Wnt activation", "microneedling add-on", "minoxidil stack", "wound-adjacent follicle neogenesis talk" ], "delivery_methods": [ "topical" ], "discussion_popularity": "Emerging", "reach": "Local", "misspellings_search_terms": [ "ptd-dbm", "ptd dbm", "ptddbm", "cxxc5 peptide", "wnt hair peptide", "ptd-dmb", "wnt", "cxxc5", "hair peptide", "scalp spray", "not minoxidil", "follicle" ], "feel_search": [ "wnt", "cxxc5", "hair peptide", "scalp spray", "not minoxidil", "follicle" ], "summary": "PTD-DBM is an experimental cell-penetrating peptide designed to interrupt CXXC5\u2013Dishevelled binding in hair-follicle research.", "search_blob": "ptd-dbm ptd-dbm ptd dbm wnt hair peptide ptd-dbm peptide protein transduction domain\u2013dishevelled binding motif cxxc5-dvl disrupting peptide ptd-dbm ptd dbm ptddbm cxxc5 peptide wnt hair peptide ptd-dmb wnt cxxc5 hair peptide scalp spray not minoxidil follicle skin/hair androgenetic alopecia / wnt activation microneedling add-on minoxidil stack wound-adjacent follicle neogenesis talk wnt cxxc5 hair peptide scalp spray not minoxidil follicle ptd-dbm is an experimental cell-penetrating peptide designed to interrupt cxxc5\u2013dishevelled binding in hair-follicle research. one serum user reported less shedding but stopped because of cost; amount and formulation were not supplied. ptd-dbm is a nasal peptide people look up for skin. pitch it as the \u201cwnt hair peptide\u201d \u2014 different job than fin/dut. not fin. not minox. people add it on top, usually as a spray. skin, hair & tissue remodeling peptide local local \u2014 a scalp spray, not a whole-body shot. local site pin topical", "legal_class": null }, { "id": 234, "slug": "nattokinase", "name": "Nattokinase", "aliases": [ "NSK-SD", "NK", "nattokinase 2000 FU", "nattokinase 10800", "fermented soybean enzyme", "natto extract" ], "type": "Non-peptide", "category": "Longevity & cellular energy", "goals_use_cases": [ "longevity", "circulation / \u201cblood flow\u201d talk", "plaque / CIMT hype", "blood pressure experiments", "long-COVID stack", "varicose / \u201csticky blood\u201d lore" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "nattokinase", "nattokinaze", "nato kinase", "nsk-sd", "nattokinase 2000", "nattokinase 12000", "fibrinolytic units", "easy bruising", "nosebleed", "plaque", "sticky blood", "fibrinolytic", "low blood pressure", "natto" ], "feel_search": [ "easy bruising", "nosebleed", "plaque", "sticky blood", "fibrinolytic", "low blood pressure", "natto" ], "summary": "Nattokinase is an enzyme from fermented soy, sold for circulation and discussed in long-COVID groups; activity is measured in fibrinolytic units.", "search_blob": "nattokinase nattokinase nsk-sd nk nattokinase 2000 fu nattokinase 10800 fermented soybean enzyme natto extract nattokinase nattokinaze nato kinase nsk-sd nattokinase 2000 nattokinase 12000 fibrinolytic units easy bruising nosebleed plaque sticky blood fibrinolytic low blood pressure natto longevity circulation / \u201cblood flow\u201d talk plaque / cimt hype blood pressure experiments long-covid stack varicose / \u201csticky blood\u201d lore easy bruising nosebleed plaque sticky blood fibrinolytic low blood pressure natto nattokinase is an enzyme from fermented soy, sold for circulation and discussed in long-covid groups; activity is measured in fibrinolytic units. some long-covid users report less fatigue or easier daily activity; others feel little. a perceived symptom change does not show that clots or plaque have been removed. nattokinase is an oral compound people look up for circulation. a minority of supplement threads claim less ache. not a peptide. not a statin. the 36% plaque number is a contested chart review. longevity & cellular energy non-peptide systemic systemic oral serine protease from natto. systemic whole-body circulating", "legal_class": null }, { "id": 235, "slug": "ru-58841", "name": "RU-58841", "aliases": [ "RU58841", "PSK-3841", "PSK3841", "RU 58841", "topical RU", "5% RU" ], "type": "Non-peptide", "category": "Skin, hair & tissue remodeling", "goals_use_cases": [ "skin/hair", "androgenetic alopecia / local androgen-receptor block", "finasteride-avoid topical add-on", "pyrilutamide comparison", "DIY ethanol/PG mix" ], "delivery_methods": [ "topical" ], "discussion_popularity": "Medium", "reach": "Local", "misspellings_search_terms": [ "ru-58841", "ru58841", "ru 58841", "psk-3841", "psk3841", "ru 5%", "topical ru", "ru58841 mix", "ru heart", "ru identity", "scalp sting", "went systemic", "heart scare", "5% ru", "ethanol pg mix", "nuclear stack", "vs kx-826" ], "feel_search": [ "scalp sting", "went systemic", "heart scare", "5% ru", "ethanol pg mix", "nuclear stack", "vs kx-826", "ru heart", "ru identity", "went systemic" ], "summary": "RU-58841 is an experimental nonsteroidal androgen-receptor blocker discussed as a topical hair-loss product.", "search_blob": "ru-58841 ru-58841 ru58841 psk-3841 psk3841 ru 58841 topical ru 5% ru ru-58841 ru58841 ru 58841 psk-3841 psk3841 ru 5% topical ru ru58841 mix ru heart ru identity scalp sting went systemic heart scare 5% ru ethanol pg mix nuclear stack vs kx-826 skin/hair androgenetic alopecia / local androgen-receptor block finasteride-avoid topical add-on pyrilutamide comparison diy ethanol/pg mix scalp sting went systemic heart scare 5% ru ethanol pg mix nuclear stack vs kx-826 ru heart ru identity went systemic ru-58841 is an experimental nonsteroidal androgen-receptor blocker discussed as a topical hair-loss product. the inspected thread includes palpitations and a perceived facial change after use, with the author reporting different degrees of recovery. ru-58841 is a topical compound people look up for hair. solos claim shed-stop and some density without a 5-ar. not pyrilutamide. not fin. a loud minority reports systemic sides. no marketed hair label. skin, hair & tissue remodeling non-peptide local local \u2014 a scalp liquid. not a whole-body anti-androgen pill. local site pin topical", "legal_class": null }, { "id": 236, "slug": "clascoterone", "name": "Clascoterone", "aliases": [ "Winlevi", "Breezula", "CB-03-01", "cortexolone 17\u03b1-propionate", "clascoterone 1%", "clascoterone 5%" ], "type": "Non-peptide", "category": "Skin, hair & tissue remodeling", "goals_use_cases": [ "skin/hair", "acne (labeled 1% cream)", "androgenetic alopecia / Breezula-class 5%", "topical AR block without swallowing 5-AR", "Winlevi vs RU vs pyrilutamide" ], "delivery_methods": [ "topical" ], "discussion_popularity": "Medium", "reach": "Local", "misspellings_search_terms": [ "clascoterone", "clasoterone", "winlevi", "breezula", "cb-03-01", "cb0301", "clascoterone 5%", "winlevi hair", "1% vs 5%", "scalp cream", "topical anti-androgen", "acne cream on hairline", "hpa axis" ], "feel_search": [ "winlevi hair", "breezula", "1% vs 5%", "scalp cream", "topical anti-androgen", "acne cream on hairline", "hpa axis" ], "summary": "Clascoterone is a topical androgen-receptor blocker: Winlevi is an acne cream, while higher-strength scalp formulations are studied for hair loss.", "search_blob": "clascoterone clascoterone winlevi breezula cb-03-01 cortexolone 17\u03b1-propionate clascoterone 1% clascoterone 5% clascoterone clasoterone winlevi breezula cb-03-01 cb0301 clascoterone 5% winlevi hair 1% vs 5% scalp cream topical anti-androgen acne cream on hairline hpa axis skin/hair acne (labeled 1% cream) androgenetic alopecia / breezula-class 5% topical ar block without swallowing 5-ar winlevi vs ru vs pyrilutamide winlevi hair breezula 1% vs 5% scalp cream topical anti-androgen acne cream on hairline hpa axis clascoterone is a topical androgen-receptor blocker: winlevi is an acne cream, while higher-strength scalp formulations are studied for hair loss. a user of a nonstandard concentrated scalp solution reports less shedding but disrupted sleep and low energy. they did not measure adrenal suppression. clascoterone is a topical cream people look up for acne and hair. reduced inflammatory lesions vs vehicle in the winlevi program. people keep asking if they can just smear the acne cream on a hairline. clinic blogs say that is a fivefold underdose. skin, hair & tissue remodeling non-peptide local topical androgen-receptor antagonist. local site pin topical", "legal_class": null }, { "id": 237, "slug": "j-147", "name": "J-147", "aliases": [ "J147", "J 147", "CAD-031 related curcumin analog talk", "Salk J147", "BioMind J-147" ], "type": "Non-peptide", "category": "Cognitive research compounds", "goals_use_cases": [ "cognition", "memory / \u201cAlzheimer\u2019s mouse drug\u201d halo", "mitochondrial / ATP synthase talk", "Dihexa stack (BioMind-class)", "longevity nootropic" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "j-147", "j147", "j 147", "jay 147", "salk j147", "biomind j147", "curcumin analog j147", "mouse alzheimer", "mitochondria", "biomind", "with dihexa", "nothing burger", "curcumin analog", "brain fog" ], "feel_search": [ "mouse alzheimer", "mitochondria", "biomind", "with dihexa", "nothing burger", "curcumin analog", "brain fog" ], "summary": "J-147 is an experimental curcumin-derived small molecule studied for Alzheimer\u2019s-related biology, with biohacker interest in cognition, mood and energy.", "search_blob": "j-147 j-147 j147 j 147 cad-031 related curcumin analog talk salk j147 biomind j-147 j-147 j147 j 147 jay 147 salk j147 biomind j147 curcumin analog j147 mouse alzheimer mitochondria biomind with dihexa nothing burger curcumin analog brain fog cognition memory / \u201calzheimer\u2019s mouse drug\u201d halo mitochondrial / atp synthase talk dihexa stack (biomind-class) longevity nootropic mouse alzheimer mitochondria biomind with dihexa nothing burger curcumin analog brain fog j-147 is an experimental curcumin-derived small molecule studied for alzheimer\u2019s-related biology, with biohacker interest in cognition, mood and energy. reports range from better mood or energy to sleepiness, fatigue, disrupted sleep or little change. some effects appear after days, but the sparse accounts do not establish a typical course. j-147 is an oral compound people look up for longevity. salk papers: memory rescue, less ad pathology, \u201cyounger\u201d mitochondria in old mice. paper-strong, diary-thin. 10\u201320 mg is vendor talk, not a human label. cognitive research compounds non-peptide systemic systemic oral experimental small molecule (curcumin-derived neurotrophic). systemic whole-body circulating", "legal_class": null }, { "id": 238, "slug": "pea", "name": "PEA", "aliases": [ "palmitoylethanolamide", "Levagen+", "palmitoyl ethanolamide", "PeaPure", "micronized PEA", "ultra-micronized PEA", "um-PEA" ], "type": "Non-peptide", "category": "Immune & inflammation adjacents", "goals_use_cases": [ "recovery", "pain / \u201cnatural endocannabinoid\u201d talk", "inflammation / mast-cell lore", "sleep when pain is the problem", "nerve pain experiments", "not phenylethylamine" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "pea", "palmitoylethanolamide", "palmitoyl ethanolamide", "levagen", "peapure", "micronized pea", "um-pea", "not phenylethylamine", "background ache", "mast cell", "slow pain relief", "inflammation", "nerve pain" ], "feel_search": [ "background ache", "mast cell", "not phenylethylamine", "slow pain relief", "levagen", "inflammation", "nerve pain" ], "summary": "PEA is an oral pain lipid, not the stimulant phenylethylamine, that people look up for inflammation. A slow drop in background ache.", "search_blob": "pea pea palmitoylethanolamide levagen+ palmitoyl ethanolamide peapure micronized pea ultra-micronized pea um-pea pea palmitoylethanolamide palmitoyl ethanolamide levagen peapure micronized pea um-pea not phenylethylamine background ache mast cell slow pain relief inflammation nerve pain recovery pain / \u201cnatural endocannabinoid\u201d talk inflammation / mast-cell lore sleep when pain is the problem nerve pain experiments not phenylethylamine background ache mast cell not phenylethylamine slow pain relief levagen inflammation nerve pain pea is an oral pain lipid, not the stimulant phenylethylamine, that people look up for inflammation. a slow drop in background ache. one person reported more manageable pelvic/back pain after about a week; later relief also involved physical therapy. pea is an oral pain lipid, not the stimulant phenylethylamine, that people look up for inflammation. a slow drop in background ache. people discuss weeks-long trials and occasional earlier relief; micronized, ultra-micronized and levagen+ products are not interchangeable. immune & inflammation adjacents non-peptide systemic systemic oral fatty-acid amide (endocannabinoid-like, ppar-\u03b1). systemic whole-body circulating", "legal_class": null }, { "id": 239, "slug": "telmisartan", "name": "Telmisartan", "aliases": [ "Micardis", "telmi", "ARB", "telmisartan 20", "telmisartan 40", "telmisartan 80" ], "type": "Non-peptide", "category": "Longevity & cellular energy", "goals_use_cases": [ "longevity", "blood pressure / endothelial talk", "longevity ARB (Attia-adjacent)", "PPAR-\u03b3 / metabolic halo", "TRT + tadalafil BP stack", "losartan comparison" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "telmisartan", "telmisartin", "micardis", "telmi", "telmisartan 20", "telmisartan 40", "arb longevity", "dizzy on standing", "blood pressure", "ppar", "vs losartan", "with tadalafil", "longevity arb", "lightheaded gym" ], "feel_search": [ "dizzy on standing", "blood pressure", "ppar", "vs losartan", "with tadalafil", "longevity arb", "lightheaded gym" ], "summary": "Telmisartan is an oral angiotensin-receptor blocker (ARB), sold as Micardis and generics for blood-pressure treatment.", "search_blob": "telmisartan telmisartan micardis telmi arb telmisartan 20 telmisartan 40 telmisartan 80 telmisartan telmisartin micardis telmi telmisartan 20 telmisartan 40 arb longevity dizzy on standing blood pressure ppar vs losartan with tadalafil longevity arb lightheaded gym longevity blood pressure / endothelial talk longevity arb (attia-adjacent) ppar-\u03b3 / metabolic halo trt + tadalafil bp stack losartan comparison dizzy on standing blood pressure ppar vs losartan with tadalafil longevity arb lightheaded gym telmisartan is an oral angiotensin-receptor blocker (arb), sold as micardis and generics for blood-pressure treatment. people report different responses to combinations with tadalafil: lower blood pressure in one account and hypotensive episodes in another. telmisartan is an oral drug for pressure. telmisartan also partially activates ppar-\u03b3 \u2014 that is the insulin-sensitivity / \u201cbetter than losartan\u201d pitch. stacks with daily tadalafil. dizziness is the watch-for, not a peptide side. longevity & cellular energy non-peptide systemic systemic oral angiotensin-ii receptor blocker (arb). systemic whole-body circulating", "legal_class": null }, { "id": 241, "slug": "pdrn", "name": "PDRN", "aliases": [ "Rejuran", "polydeoxyribonucleotide", "Rejuran Healer", "salmon DNA", "polynucleotide PN", "PDRN mesotherapy" ], "type": "Non-peptide", "category": "Skin, hair & tissue remodeling", "goals_use_cases": [ "skin/hair", "K-beauty \u201csalmon DNA\u201d facial", "under-eye / texture / glow", "scalp mesotherapy", "post-laser recovery talk" ], "delivery_methods": [ "intradermal" ], "discussion_popularity": "Medium", "reach": "Local", "misspellings_search_terms": [ "pdrn", "rejuran", "rejuran healer", "salmon dna", "polydeoxyribonucleotide", "polynucleotide", "pdrn hair", "salmon sperm facial", "papules", "pillow face", "under eye", "scalp meso", "bruise grid", "pn vs pdrn", "not filler", "c-pdrn serum" ], "feel_search": [ "papules", "salmon dna", "pillow face", "under eye", "rejuran", "scalp meso", "bruise grid", "pn vs pdrn", "not filler", "c-pdrn serum" ], "summary": "PDRN is a DNA-fragment material discussed for skin repair. It differs from the longer polynucleotide material used in Rejuran injections.", "search_blob": "pdrn pdrn rejuran polydeoxyribonucleotide rejuran healer salmon dna polynucleotide pn pdrn mesotherapy pdrn rejuran rejuran healer salmon dna polydeoxyribonucleotide polynucleotide pdrn hair salmon sperm facial papules pillow face under eye scalp meso bruise grid pn vs pdrn not filler c-pdrn serum skin/hair k-beauty \u201csalmon dna\u201d facial under-eye / texture / glow scalp mesotherapy post-laser recovery talk papules salmon dna pillow face under eye rejuran scalp meso bruise grid pn vs pdrn not filler c-pdrn serum pdrn is a dna-fragment material discussed for skin repair. it differs from the longer polynucleotide material used in rejuran injections. one treatment account described calmer redness and better hydration, but less lasting tightening than rejuran; other procedures were also involved. pdrn is a compound people look up for skin and is not a peptide. less crepey, more bounce over a series, not a one-and-done filter. not a peptide. cosmetic skin-booster goals differ from volume filling; hair mesotherapy is additional, thinner-evidence discussion. skin, hair & tissue remodeling non-peptide local local \u2014 skin injections / mesotherapy, not a whole-body shot. local site pin topical", "legal_class": null }, { "id": 242, "slug": "agmatine", "name": "Agmatine", "aliases": [ "agmatine sulfate", "decarboxylated arginine", "AGM", "agmatine 1g", "GDA agmatine talk" ], "type": "Non-peptide", "category": "Cognitive / nootropic peptides", "goals_use_cases": [ "cognition", "performance", "gym pump / nitric-oxide adjacent", "nerve pain experiments", "stimulant-tolerance lore", "mood / NMDA talk" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "agmatine", "agmantine", "agmatine sulfate", "agmatin", "agmatine 500", "agmatine 1g", "decarboxylated arginine", "pump", "blunts stims", "flat mood", "nerve pain", "empty stomach", "not citrulline" ], "feel_search": [ "pump", "blunts stims", "flat mood", "nerve pain", "empty stomach", "not citrulline", "agmatine sulfate" ], "summary": "Agmatine is an arginine-derived compound sold as agmatine sulfate, discussed for anxiety, nerve pain and workout pumps.", "search_blob": "agmatine agmatine agmatine sulfate decarboxylated arginine agm agmatine 1g gda agmatine talk agmatine agmantine agmatine sulfate agmatin agmatine 500 agmatine 1g decarboxylated arginine pump blunts stims flat mood nerve pain empty stomach not citrulline cognition performance gym pump / nitric-oxide adjacent nerve pain experiments stimulant-tolerance lore mood / nmda talk pump blunts stims flat mood nerve pain empty stomach not citrulline agmatine sulfate agmatine is an arginine-derived compound sold as agmatine sulfate, discussed for anxiety, nerve pain and workout pumps. one anxiety account describes several hours of calm followed by returning anxiety; another says the effect is patchy. that does not establish a universal duration. agmatine is an oral compound people look up for cognition. some nootropic posts like it; some call it emotionally flat. can blunt the buzz you wanted. not citrulline. not a peptide. cognitive / nootropic peptides non-peptide systemic systemic oral arginine metabolite (not a peptide). systemic whole-body circulating", "legal_class": null }, { "id": 243, "slug": "pentosan-pps", "name": "Pentosan PPS", "aliases": [ "pentosan polysulfate", "Elmiron", "pentosan polysulfate sodium", "PPS", "iPPS", "Adequan-adjacent pentosan talk" ], "type": "Non-peptide", "category": "Healing & repair", "goals_use_cases": [ "recovery", "interstitial cystitis (labeled oral)", "joint / cartilage regenerative-clinic talk", "bladder GAG-layer lore", "maculopathy watch-for" ], "delivery_methods": [ "oral", "subcutaneous" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "pentosan", "pentosan pps", "pentosan polysulfate", "elmiron", "elmeron", "ipps", "pps injection", "pentosan maculopathy", "maculopathy", "night vision", "bladder pain", "knee injection", "not bpc", "reading trouble" ], "feel_search": [ "maculopathy", "night vision", "bladder pain", "knee injection", "elmiron", "not bpc", "reading trouble" ], "summary": "Pentosan polysulfate is an oral medicine people look up for bladder pain. Relief in those who respond is often months, not days.", "search_blob": "pentosan pps pentosan-pps pentosan polysulfate elmiron pentosan polysulfate sodium pps ipps adequan-adjacent pentosan talk pentosan pentosan pps pentosan polysulfate elmiron elmeron ipps pps injection pentosan maculopathy maculopathy night vision bladder pain knee injection not bpc reading trouble recovery interstitial cystitis (labeled oral) joint / cartilage regenerative-clinic talk bladder gag-layer lore maculopathy watch-for maculopathy night vision bladder pain knee injection elmiron not bpc reading trouble pentosan polysulfate is an oral medicine people look up for bladder pain. relief in those who respond is often months, not days. oral bladder-pain reports describe slow, variable relief; one long-term user noticed less urgency and pain, while another was still waiting near six months. pentosan polysulfate is an oral medicine people look up for bladder pain. relief in those who respond is often months, not days. not bpc. cumulative grams matter. reading trouble is the scare, not a gi footnote. healing & repair non-peptide systemic systemic heparinoid polysaccharide. systemic whole-body circulating", "legal_class": null }, { "id": 244, "slug": "berberine", "name": "Berberine", "aliases": [ "berberine HCl", "dihydroberberine", "berberine 500", "GlucoVantage", "\u201cnatural metformin\u201d", "Oregon grape alkaloid talk" ], "type": "Non-peptide", "category": "Metabolic & longevity adjacents", "goals_use_cases": [ "fat loss", "fat loss / glucose talk", "metformin comparison", "lipids / \u201cpoor man\u2019s GLP\u201d lore", "PCOS-adjacent community", "AMPK" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "berberine", "berberine hcl", "berberin", "dihydroberberine", "glucovantage", "berberine 500", "natural metformin", "hypoglycemia", "glucose crash", "diarrhea", "cgm", "yellow stool", "ampk", "with meals", "stack with metformin" ], "feel_search": [ "diarrhea", "natural metformin", "cgm", "yellow stool", "ampk", "dihydroberberine", "with meals", "glucose crash", "hypoglycemia", "stack with metformin" ], "summary": "Berberine is a plant alkaloid sold as an oral supplement for glucose and lipid control, with frequent weight-loss discussion.", "search_blob": "berberine berberine berberine hcl dihydroberberine berberine 500 glucovantage \u201cnatural metformin\u201d oregon grape alkaloid talk berberine berberine hcl berberin dihydroberberine glucovantage berberine 500 natural metformin hypoglycemia glucose crash diarrhea cgm yellow stool ampk with meals stack with metformin fat loss fat loss / glucose talk metformin comparison lipids / \u201cpoor man\u2019s glp\u201d lore pcos-adjacent community ampk diarrhea natural metformin cgm yellow stool ampk dihydroberberine with meals glucose crash hypoglycemia stack with metformin berberine is a plant alkaloid sold as an oral supplement for glucose and lipid control, with frequent weight-loss discussion. some users describe loose stools or stomach discomfort; others report none. weight-loss accounts in this thread include calorie restriction, exercise or combination products. berberine is an oral supplement people look up for glucose and fat loss. glucose n=1s start posting cgm wiggles. not a glp-1. dihydroberberine is the gi-workaround people upgrade to. metabolic & longevity adjacents non-peptide systemic systemic oral plant alkaloid (berberine hcl). systemic whole-body circulating", "legal_class": null }, { "id": 245, "slug": "choline", "name": "Choline", "aliases": [ "Alpha-GPC", "citicoline", "CDP-choline", "choline bitartrate", "alpha GPC", "phosphatidylcholine", "Cognizin" ], "type": "Non-peptide", "category": "Cognitive research compounds", "goals_use_cases": [ "cognition", "racetam \u201ccholine dump\u201d prevention", "focus / memory stack", "gym power (Alpha-GPC 600 mg talk)", "eggs vs a capsule" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "choline", "alpha gpc", "alphagpc", "cdp choline", "citicoline", "choline bitartrate", "cognizin", "choline dump", "50% gpc", "racetam headache", "fishy sweat", "tmao", "focus", "bitartrate fishy" ], "feel_search": [ "racetam headache", "fishy sweat", "alpha gpc", "choline dump", "tmao", "focus", "citicoline", "cognizin", "50% gpc", "bitartrate fishy" ], "summary": "Choline is an essential nutrient; supplements such as alpha-GPC, citicoline and phosphatidylcholine supply it in different forms.", "search_blob": "choline choline alpha-gpc citicoline cdp-choline choline bitartrate alpha gpc phosphatidylcholine cognizin choline alpha gpc alphagpc cdp choline citicoline choline bitartrate cognizin choline dump 50% gpc racetam headache fishy sweat tmao focus bitartrate fishy cognition racetam \u201ccholine dump\u201d prevention focus / memory stack gym power (alpha-gpc 600 mg talk) eggs vs a capsule racetam headache fishy sweat alpha gpc choline dump tmao focus citicoline cognizin 50% gpc bitartrate fishy choline is an essential nutrient; supplements such as alpha-gpc, citicoline and phosphatidylcholine supply it in different forms. one alpha-gpc account describes a headache followed by energy and clearer reading. eggs, vyvanse and other supplements were also involved. choline is an oral compound people look up for cognition. a subset feels a clean focus bump; another subset feels tense or sweaty. racetam headache insurance. too much choline is also a headache. forms are not equal milligrams. cognitive research compounds non-peptide systemic systemic choline \u2014 several oral forms that are not the same milligram. systemic whole-body circulating", "legal_class": null }, { "id": 246, "slug": "atx-304", "name": "ATX-304", "aliases": [ "O-304", "OS-01", "ATX304", "Amplifier Therapeutics ATX-304", "O304", "ATX 304", "Cambrian ATX-304" ], "type": "Non-peptide", "category": "Metabolic & longevity adjacents", "goals_use_cases": [ "fat loss", "metabolic health", "AMPK", "mitochondria", "GLP-1 stack talk", "endurance" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "atx-304", "atx304", "atx 304", "o-304", "o304", "os-01", "os01", "ampk activator", "mots-c replacement", "ampk", "mots-c", "oral", "uncoupling", "glp stack", "metformin pivot", "fatty liver", "4am crash", "rewire", "phase 1b" ], "feel_search": [ "ampk", "mots-c", "oral", "uncoupling", "glp stack", "metformin pivot", "fatty liver", "4am crash", "rewire", "phase 1b" ], "summary": "ATX-304 (O-304) is an investigational oral small molecule studied for metabolic effects and discussed for energy and fat loss.", "search_blob": "atx-304 atx-304 o-304 os-01 atx304 amplifier therapeutics atx-304 o304 atx 304 cambrian atx-304 atx-304 atx304 atx 304 o-304 o304 os-01 os01 ampk activator mots-c replacement ampk mots-c oral uncoupling glp stack metformin pivot fatty liver 4am crash rewire phase 1b fat loss metabolic health ampk mitochondria glp-1 stack talk endurance ampk mots-c oral uncoupling glp stack metformin pivot fatty liver 4am crash rewire phase 1b atx-304 (o-304) is an investigational oral small molecule studied for metabolic effects and discussed for energy and fat loss. one public account reports more sweating during cardio, with additional heat when combined with slu. exercise and co-use prevent an isolated atx effect claim. atx-304 is an oral compound people look up for fat loss. energy, training volume, \u201cgo harder without the crash\u201d vs mots-c flops. 100\u2013150 mg n=1s. stacked with glps. not metformin. metabolic & longevity adjacents non-peptide systemic systemic oral small molecule. systemic whole-body circulating", "legal_class": null }, { "id": 247, "slug": "pn-477", "name": "PN-477", "aliases": [ "PN477", "PN-477o", "PN-477sc", "Protagonist PN-477", "PN 477", "PTGX triple-G" ], "type": "Peptide", "category": "Metabolic / GLP-1 class", "goals_use_cases": [ "fat loss", "appetite control", "oral GLP talk", "metabolic health", "reta comparison" ], "delivery_methods": [ "oral", "subcutaneous" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "pn-477", "pn477", "pn 477", "pn-477o", "pn-477sc", "protagonist peptide", "ptgx", "reta competitor", "oral triple g", "protagonist", "pn477o", "amylin rumor", "pipeline" ], "feel_search": [ "reta competitor", "oral triple g", "protagonist", "pn477o", "amylin rumor", "pipeline" ], "summary": "PN-477 is an obesity-development candidate targeting GLP-1, GIP and glucagon receptors, with oral and injectable versions.", "search_blob": "pn-477 pn-477 pn477 pn-477o pn-477sc protagonist pn-477 pn 477 ptgx triple-g pn-477 pn477 pn 477 pn-477o pn-477sc protagonist peptide ptgx reta competitor oral triple g protagonist pn477o amylin rumor pipeline fat loss appetite control oral glp talk metabolic health reta comparison reta competitor oral triple g protagonist pn477o amylin rumor pipeline pn-477 is an obesity-development candidate targeting glp-1, gip and glucagon receptors, with oral and injectable versions. the inspected social post discusses a future oral or injected drug; it contains no first-person experience. pn-477 is an investigational compound people look up for fat loss and appetite. not a food-noise diary compound today. company language is glp-1/gip/glucagon. amylin-on-the-side is rumor. metabolic / glp-1 class peptide systemic systemic multi-agonist peptide. systemic whole-body circulating", "legal_class": null }, { "id": 248, "slug": "tak-653", "name": "TAK-653", "aliases": [ "osavampator", "TAK653", "AMPA PAM TAK-653", "TAK 653" ], "type": "Non-peptide", "category": "Cognitive research compounds", "goals_use_cases": [ "cognition", "focus / working memory", "depression-pipeline talk", "nootropic stacks" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "tak-653", "tak653", "tak 653", "osavampator", "ampa pam", "tak 653 dose", "ampa", "digit span", "working memory", "vivid dreams", "cerebrolysin stack" ], "feel_search": [ "ampa", "digit span", "osavampator", "working memory", "vivid dreams", "cerebrolysin stack" ], "summary": "TAK-653, or osavampator, is an investigational oral AMPA-receptor positive modulator from a depression program, discussed for cognition.", "search_blob": "tak-653 tak-653 osavampator tak653 ampa pam tak-653 tak 653 tak-653 tak653 tak 653 osavampator ampa pam tak 653 dose ampa digit span working memory vivid dreams cerebrolysin stack cognition focus / working memory depression-pipeline talk nootropic stacks ampa digit span osavampator working memory vivid dreams cerebrolysin stack tak-653, or osavampator, is an investigational oral ampa-receptor positive modulator from a depression program, discussed for cognition. one user described good retention and focus but also head pressure, careless mistakes, irritability and vivid dreams. tak-653 is an oral compound people look up for focus. \u201ci can articulate thoughts\u201d r/nootopics flavor. nootropic rooms say 2 mg. not semax. not a racetam. cognitive research compounds non-peptide systemic systemic oral ampa receptor positive allosteric modulator. systemic whole-body circulating", "legal_class": null }, { "id": 249, "slug": "brp", "name": "BRP", "aliases": [ "BRINP2-related peptide", "BRINP2", "THRILRRLFNLC", "BRINP2 related peptide", "BRINP-2", "Stanford BRP", "natural Ozempic peptide" ], "type": "Peptide", "category": "Metabolic / GLP-1 class", "goals_use_cases": [ "fat loss", "appetite control", "metabolic health", "non-GLP hunger talk", "muscle-sparing cut talk" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "brp", "brinp2", "brinp-2", "brinp2 related peptide", "thrillrrlfnlc", "natural ozempic peptide", "stanford peptide brp", "natural ozempic", "appetite peptide", "no nausea glp", "stanford peptide", "12 amino acid" ], "feel_search": [ "natural ozempic", "brinp2", "appetite peptide", "no nausea glp", "stanford peptide", "12 amino acid" ], "summary": "BRP (BRINP2-related peptide) is a 12-amino-acid research peptide studied for reducing food intake in animals.", "search_blob": "brp brp brinp2-related peptide brinp2 thrilrrlfnlc brinp2 related peptide brinp-2 stanford brp natural ozempic peptide brp brinp2 brinp-2 brinp2 related peptide thrillrrlfnlc natural ozempic peptide stanford peptide brp natural ozempic appetite peptide no nausea glp stanford peptide 12 amino acid fat loss appetite control metabolic health non-glp hunger talk muscle-sparing cut talk natural ozempic brinp2 appetite peptide no nausea glp stanford peptide 12 amino acid brp (brinp2-related peptide) is a 12-amino-acid research peptide studied for reducing food intake in animals. the inspected discussion proposes a future two-week experiment and repeats animal findings. it reports no completed personal experience. brp is a research peptide people look up for appetite and fat loss. acute intake drop in hours; 14-day fat-mass figures. not a human titration. mice and minipigs only. human milligrams do not exist. amidation is the identity check. metabolic / glp-1 class peptide systemic systemic 12-amino-acid peptide from brinp2. systemic whole-body circulating", "legal_class": null }, { "id": 250, "slug": "mtx-325", "name": "MTX-325", "aliases": [ "MTX325", "MTX115325", "USP30 inhibitor MTX-325", "MTX 325", "MTX-115325", "Mission MTX325" ], "type": "Non-peptide", "category": "Mitochondrial & metabolic compounds", "goals_use_cases": [ "longevity / cellular energy", "mitophagy / mitochondrial recycling", "Parkinson pipeline talk", "\u201cgiga urolithin\u201d talk", "brain mito quality" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "mtx-325", "mtx325", "mtx 325", "mtx115325", "usp30", "mission therapeutics", "giga urolithin", "mitophagy pill", "parkinson oral", "brain mitochondria" ], "feel_search": [ "giga urolithin", "usp30", "mitophagy pill", "parkinson oral", "mission therapeutics", "brain mitochondria" ], "summary": "MTX325 is an experimental oral USP30 inhibitor being studied for Parkinson's disease by promoting removal of damaged mitochondria.", "search_blob": "mtx-325 mtx-325 mtx325 mtx115325 usp30 inhibitor mtx-325 mtx 325 mtx-115325 mission mtx325 mtx-325 mtx325 mtx 325 mtx115325 usp30 mission therapeutics giga urolithin mitophagy pill parkinson oral brain mitochondria longevity / cellular energy mitophagy / mitochondrial recycling parkinson pipeline talk \u201cgiga urolithin\u201d talk brain mito quality giga urolithin usp30 mitophagy pill parkinson oral mission therapeutics brain mitochondria mtx325 is an experimental oral usp30 inhibitor being studied for parkinson's disease by promoting removal of damaged mitochondria. the reviewed sources do not provide a reliable human feel profile. brain penetration and safety testing do not establish better energy, focus or parkinson's symptoms. mtx-325 is an oral compound people look up for longevity. there is no copied week-1 feel. phase 1 brain-penetrant talk. no public diy milligrams. not mitopure. mitochondrial & metabolic compounds non-peptide systemic systemic oral small molecule. systemic whole-body circulating", "legal_class": null }, { "id": 251, "slug": "flgr-242", "name": "FLGR-242", "aliases": [ "FLGR242", "FGLR242", "recombinant follistatin", "SlimAssist", "FS I-I", "albumin-bound follistatin", "MicroFLGR", "FLGR 242", "FGLR-242", "Follistatin FLGR242", "BioLongevity FLGR242", "FSI-I", "FS-I/I", "BLL follistatin" ], "type": "Peptide", "category": "Growth factors / muscle", "goals_use_cases": [ "muscle growth", "myostatin inhibition", "GLP muscle-spare talk", "recomp", "vs Follistatin 344" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "flgr-242", "flgr242", "fglr242", "fglr-242", "recombinant follistatin", "biolongevity follistatin", "slimassist", "flgr 242 dose", "fs i-i", "fsi-i", "microflgr", "flgr forever", "flgr dexa", "myostatin", "glp muscle spare", "biolongevity", "19 day half life", "fst-344 vs flgr", "lose muscle when stop", "1.5 lb a week", "alex padron", "slimassist women" ], "feel_search": [ "recombinant follistatin", "myostatin", "glp muscle spare", "biolongevity", "19 day half life", "fst-344 vs flgr", "lose muscle when stop", "1.5 lb a week", "alex padron", "slimassist women" ], "summary": "FLGR-242 is a seller-named injectable modified-follistatin product marketed for muscle growth; its claimed long duration is not established human PK.", "search_blob": "flgr-242 flgr-242 flgr242 fglr242 recombinant follistatin slimassist fs i-i albumin-bound follistatin microflgr flgr 242 fglr-242 follistatin flgr242 biolongevity flgr242 fsi-i fs-i/i bll follistatin flgr-242 flgr242 fglr242 fglr-242 recombinant follistatin biolongevity follistatin slimassist flgr 242 dose fs i-i fsi-i microflgr flgr forever flgr dexa myostatin glp muscle spare biolongevity 19 day half life fst-344 vs flgr lose muscle when stop 1.5 lb a week alex padron slimassist women muscle growth myostatin inhibition glp muscle-spare talk recomp vs follistatin 344 recombinant follistatin myostatin glp muscle spare biolongevity 19 day half life fst-344 vs flgr lose muscle when stop 1.5 lb a week alex padron slimassist women flgr-242 is a seller-named injectable modified-follistatin product marketed for muscle growth; its claimed long duration is not established human pk. one user describes rapid apparent muscle change after a slimassist product and changes their planned interval. no verified body-composition measurement supports the impression. flgr-242 is an oral peptide people look up for muscle. skeletal-muscle gain / recomp while staying lean \u2014 jay\u2019s \u201c7\u201310 lb lean\u201d line in the course copy. n=1, shop-adjacent. vendor milligrams every 1\u20132 weeks, not 100 mcg daily fs-344. people now also ask whether the look disappears when you stop. growth factors / muscle peptide systemic systemic recombinant follistatin analog with an albumin-binding tail. systemic whole-body circulating", "legal_class": null }, { "id": 253, "slug": "lithium-orotate", "name": "Lithium orotate", "aliases": [ "OTC lithium", "low-dose lithium", "Li-orotate", "lithium orotate 5 mg", "elemental lithium supplement" ], "type": "Non-peptide", "category": "Cognitive research compounds", "goals_use_cases": [ "mood", "longevity / Alzheimer\u2019s talk", "microdose lithium", "vs psychiatric lithium carbonate" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "lithium orotate", "lithium oratate", "li orotate", "otc lithium", "5 mg lithium", "yankner lithium", "orotate", "microdose lithium", "yankner", "mood mineral", "alzheimers lithium" ], "feel_search": [ "orotate", "microdose lithium", "yankner", "mood mineral", "5 mg lithium", "alzheimers lithium" ], "summary": "Lithium orotate is a lithium salt sold as an oral supplement for mood-related purposes; elemental lithium and total salt weight are different label numbers.", "search_blob": "lithium orotate lithium-orotate otc lithium low-dose lithium li-orotate lithium orotate 5 mg elemental lithium supplement lithium orotate lithium oratate li orotate otc lithium 5 mg lithium yankner lithium orotate microdose lithium yankner mood mineral alzheimers lithium mood longevity / alzheimer\u2019s talk microdose lithium vs psychiatric lithium carbonate orotate microdose lithium yankner mood mineral 5 mg lithium alzheimers lithium lithium orotate is a lithium salt sold as an oral supplement for mood-related purposes; elemental lithium and total salt weight are different label numbers. lithium orotate is an oral compound people look up for mood. some describe calm, no effect, agitation, emotional flattening or vivid dreams. 5\u201310 mg elemental talk. yankner headlines. read the label math. cognitive research compounds non-peptide systemic systemic oral lithium salt sold as a supplement. systemic whole-body circulating", "legal_class": null }, { "id": 254, "slug": "l-theanine", "name": "L-theanine", "aliases": [ "theanine", "Suntheanine", "L theanine", "N-ethyl-L-glutamine", "tea theanine" ], "type": "Non-peptide", "category": "Cognitive research compounds", "goals_use_cases": [ "cognition", "calm focus", "caffeine stack", "sleep onset", "anxiety-adjacent talk" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "l-theanine", "theanine", "l theanine", "suntheanine", "theanine coffee", "theanine sleep", "coffee stack", "calm caffeine", "alpha waves", "sleep amino", "tea" ], "feel_search": [ "coffee stack", "suntheanine", "calm caffeine", "alpha waves", "sleep amino", "tea" ], "summary": "L-theanine is an amino acid found in tea, used as a supplement for calmer focus with caffeine or for relaxation before sleep.", "search_blob": "l-theanine l-theanine theanine suntheanine l theanine n-ethyl-l-glutamine tea theanine l-theanine theanine l theanine suntheanine theanine coffee theanine sleep coffee stack calm caffeine alpha waves sleep amino tea cognition calm focus caffeine stack sleep onset anxiety-adjacent talk coffee stack suntheanine calm caffeine alpha waves sleep amino tea l-theanine is an amino acid found in tea, used as a supplement for calmer focus with caffeine or for relaxation before sleep. the effect is often described as subtle reduced jitters rather than a strong calming sensation. reviewed reports range from a few hours to an all-day impression, with some users noticing little. l-theanine is an oral compound people look up for focus. \u201ctakes the edge off\u201d without a benzo hangover. the 200 mg capsule also appears in night stacks next to magnesium. coffee-pairing notes discuss 100\u2013200 mg and bedtime notes 200\u2013400 mg; these reported amounts are not a dosing ceiling. cognitive research compounds non-peptide systemic systemic amino acid from tea. systemic whole-body circulating", "legal_class": null }, { "id": 255, "slug": "9-me-bc", "name": "9-Me-BC", "aliases": [ "9-methyl-\u03b2-carboline", "9-MBC", "9MeBC", "9-methyl-beta-carboline" ], "type": "Non-peptide", "category": "Cognitive research compounds", "goals_use_cases": [ "cognition", "dopamine restoration talk", "post-stim anhedonia", "motivation / social", "Parkinson-adjacent lore" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "9-me-bc", "9mebc", "9-mbc", "9 methyl beta carboline", "9-methyl-b-carboline", "9 me bc", "dopamine restore", "photosensitivity", "anhedonia", "9mbc", "after adderall", "beta carboline" ], "feel_search": [ "dopamine restore", "photosensitivity", "anhedonia", "9mbc", "after adderall", "beta carboline" ], "summary": "9-Me-BC (9-methyl-\u03b2-carboline) is a research nootropic discussed for motivation and mood.", "search_blob": "9-me-bc 9-me-bc 9-methyl-\u03b2-carboline 9-mbc 9mebc 9-methyl-beta-carboline 9-me-bc 9mebc 9-mbc 9 methyl beta carboline 9-methyl-b-carboline 9 me bc dopamine restore photosensitivity anhedonia 9mbc after adderall beta carboline cognition dopamine restoration talk post-stim anhedonia motivation / social parkinson-adjacent lore dopamine restore photosensitivity anhedonia 9mbc after adderall beta carboline 9-me-bc (9-methyl-\u03b2-carboline) is a research nootropic discussed for motivation and mood. a multi-compound log describes increased enjoyment and focus but also intense, volatile mood. bromantane, caffeine and other co-use blur attribution. 9-me-bc is an oral compound people look up for motivation. some describe a clean lift, nothing, or feeling wired. 15 mg appears in cycle reports. photosensitivity is a concern; these reports do not establish human safety or a restoration protocol. cognitive research compounds non-peptide systemic systemic oral \u03b2-carboline. systemic whole-body circulating", "legal_class": null }, { "id": 256, "slug": "empagliflozin", "name": "Empagliflozin", "aliases": [ "Jardiance", "SGLT2 inhibitor empagliflozin", "empa", "Jardiance 10 mg", "Jardiance 25 mg" ], "type": "Non-peptide", "category": "Metabolic & longevity adjacents", "goals_use_cases": [ "longevity / SGLT2 talk", "glucose", "heart / kidney labeled talk", "vs metformin" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "empagliflozin", "jardiance", "sglt2", "empagloflozin", "jardiance 10", "flozin", "yeast", "attia", "pee sugar" ], "feel_search": [ "jardiance", "sglt2", "flozin", "yeast", "attia", "pee sugar" ], "summary": "Empagliflozin (Jardiance) is an SGLT2-inhibitor tablet that increases glucose loss in urine, used in diabetes, heart-failure and kidney care.", "search_blob": "empagliflozin empagliflozin jardiance sglt2 inhibitor empagliflozin empa jardiance 10 mg jardiance 25 mg empagliflozin jardiance sglt2 empagloflozin jardiance 10 flozin yeast attia pee sugar longevity / sglt2 talk glucose heart / kidney labeled talk vs metformin jardiance sglt2 flozin yeast attia pee sugar empagliflozin (jardiance) is an sglt2-inhibitor tablet that increases glucose loss in urine, used in diabetes, heart-failure and kidney care. people discuss more urination and thirst, some with recurrent genital yeast symptoms, while others report good glucose control without problems. empagliflozin, sold as jardiance, is a prescription oral sglt2 inhibitor that increases urinary glucose excretion. some glucose leaves in urine. pee extra sugar. yeast is the meme side. not metformin. not a glp. metabolic & longevity adjacents non-peptide systemic systemic oral sglt2 inhibitor. systemic whole-body circulating", "legal_class": null }, { "id": 257, "slug": "vesilute", "name": "Vesilute", "aliases": [ "ED peptide", "Glu-Asp", "bladder cytogen", "Glu-Asp dipeptide", "H-Glu-Asp-OH", "ED dipeptide", "Vesilut", "Khavinson bladder peptide", "A-12 synthetic counterpart" ], "type": "Peptide", "category": "Organ bioregulators", "goals_use_cases": [ "bladder / urinary comfort (discussed)", "nocturia / overactive-bladder talk", "prostate-adjacent urinary flow talk", "BPH-adjacent community stacks", "longevity / organ-bioregulator calendars" ], "delivery_methods": [ "oral", "subcutaneous" ], "discussion_popularity": "Emerging", "reach": "Mixed", "misspellings_search_terms": [ "vesilute", "vesilut", "glu-asp", "ed peptide", "bladder bioregulator", "vesilute dosage", "vesilute vs vesugen", "vesilute vs visoluten", "bladder / urinary comfort (discussed)", "nocturia / overactive-bladder talk", "prostate-adjacent urinary flow talk", "bph-adjacent community stacks", "longevity / organ-bioregulator calendars" ], "feel_search": [ "bladder / urinary comfort (discussed)", "nocturia / overactive-bladder talk", "prostate-adjacent urinary flow talk", "bph-adjacent community stacks", "longevity / organ-bioregulator calendars" ], "summary": "Vesilute is the synthetic Glu-Asp dipeptide, marketed in the Russian bioregulator tradition for bladder and urogenital support.", "search_blob": "vesilute vesilute ed peptide glu-asp bladder cytogen glu-asp dipeptide h-glu-asp-oh ed dipeptide vesilut khavinson bladder peptide a-12 synthetic counterpart vesilute vesilut glu-asp ed peptide bladder bioregulator vesilute dosage vesilute vs vesugen vesilute vs visoluten bladder / urinary comfort (discussed) nocturia / overactive-bladder talk prostate-adjacent urinary flow talk bph-adjacent community stacks longevity / organ-bioregulator calendars bladder / urinary comfort (discussed) nocturia / overactive-bladder talk prostate-adjacent urinary flow talk bph-adjacent community stacks longevity / organ-bioregulator calendars bladder / urinary comfort (discussed) nocturia / overactive-bladder talk prostate-adjacent urinary flow talk bph-adjacent community stacks longevity / organ-bioregulator calendars vesilute is the synthetic glu-asp dipeptide, marketed in the russian bioregulator tradition for bladder and urogenital support. one prostamax/vesilute user described less pain and fewer nighttime bathroom trips, with better sleep; the two-product result cannot isolate vesilute. vesilute is a peptide people look up for longevity. logistics (pin sting or capsule) beat any bladder feel. not oxybutynin, not tamsulosin, not a pelvic-floor program, not a uti antibiotic. organ bioregulators peptide mixed aimed at bladder tissue in the writeups, but people still swallow capsules or pin it like any other short peptide. mixed local systemic", "legal_class": null }, { "id": 258, "slug": "chitomur", "name": "Chitomur", "aliases": [ "A-12", "bladder cytomax", "A-12 bladder bioregulator", "Khavinson bladder complex", "Chitomur peptide" ], "type": "Peptide", "category": "Organ bioregulators", "goals_use_cases": [ "bladder / urinary comfort (discussed)", "overactive-bladder talk", "nocturia talk", "BPH-adjacent community stacks", "longevity / organ-bioregulator calendars" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "chitomur", "chitomur peptide", "a-12 bioregulator", "a12 bladder", "chitomur dosage", "chitomur vs vesilute", "bladder / urinary comfort (discussed)", "overactive-bladder talk", "nocturia talk", "bph-adjacent community stacks", "longevity / organ-bioregulator calendars" ], "feel_search": [ "bladder / urinary comfort (discussed)", "overactive-bladder talk", "nocturia talk", "bph-adjacent community stacks", "longevity / organ-bioregulator calendars" ], "summary": "Chitomur is an animal-bladder peptide complex sold as a bioregulator for urinary symptoms, distinct from the single peptide Vesilute.", "search_blob": "chitomur chitomur a-12 bladder cytomax a-12 bladder bioregulator khavinson bladder complex chitomur peptide chitomur chitomur peptide a-12 bioregulator a12 bladder chitomur dosage chitomur vs vesilute bladder / urinary comfort (discussed) overactive-bladder talk nocturia talk bph-adjacent community stacks longevity / organ-bioregulator calendars bladder / urinary comfort (discussed) overactive-bladder talk nocturia talk bph-adjacent community stacks longevity / organ-bioregulator calendars bladder / urinary comfort (discussed) overactive-bladder talk nocturia talk bph-adjacent community stacks longevity / organ-bioregulator calendars chitomur is an animal-bladder peptide complex sold as a bioregulator for urinary symptoms, distinct from the single peptide vesilute. a tablet user reports improvement after starting in january and plans to switch products for cost. that is an early account, not a completed comparison with vesilute. chitomur is a peptide people look up for longevity. secondary khavinson writeups claim better basic urination parameters in older men. natural short-peptide complex from bladder tissue in the khavinson cytomax line, catalogued as a-12. not a single named amino-acid sequence like vesilute. organ bioregulators peptide systemic aimed at bladder tissue in the catalogs, but people still take it as a whole-body capsule. systemic whole-body circulating", "legal_class": null }, { "id": 259, "slug": "chelohart", "name": "Chelohart", "aliases": [ "A-14", "heart cytomax", "A-14 heart bioregulator", "Khavinson heart complex", "Chelohart peptide" ], "type": "Peptide", "category": "Organ bioregulators", "goals_use_cases": [ "cardiovascular / heart-tissue talk", "longevity / organ-bioregulator calendars", "PVC / palpitations curiosity (community)", "post-stress heart-support narratives" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "chelohart", "chelohart peptide", "a-14 bioregulator", "a14 heart", "chelohart dosage", "chelohart vs cardiogen", "cardiovascular / heart-tissue talk", "longevity / organ-bioregulator calendars", "pvc / palpitations curiosity (community)", "post-stress heart-support narratives" ], "feel_search": [ "cardiovascular / heart-tissue talk", "longevity / organ-bioregulator calendars", "pvc / palpitations curiosity (community)", "post-stress heart-support narratives" ], "summary": "Chelohart is a natural young-animal heart peptide complex, commonly described as A-14 in capsules. Energy, less flutter awareness \u2014 easy to confound.", "search_blob": "chelohart chelohart a-14 heart cytomax a-14 heart bioregulator khavinson heart complex chelohart peptide chelohart chelohart peptide a-14 bioregulator a14 heart chelohart dosage chelohart vs cardiogen cardiovascular / heart-tissue talk longevity / organ-bioregulator calendars pvc / palpitations curiosity (community) post-stress heart-support narratives cardiovascular / heart-tissue talk longevity / organ-bioregulator calendars pvc / palpitations curiosity (community) post-stress heart-support narratives cardiovascular / heart-tissue talk longevity / organ-bioregulator calendars pvc / palpitations curiosity (community) post-stress heart-support narratives chelohart is a natural young-animal heart peptide complex, commonly described as a-14 in capsules. energy, less flutter awareness \u2014 easy to confound. one user reports better wearable heart-rate, hrv and sleep scores during a month combining chelohart, svetinorm and ventfort. the three-product stack prevents attribution. chelohart is a natural young-animal heart peptide complex, commonly described as a-14 in capsules. energy, less flutter awareness \u2014 easy to confound. a 2026 post described friends mega-dosing oral chelohart + ventfort after scad / heart-failure diagnoses. anecdote, patreon protocol energy, not a paper. organ bioregulators peptide systemic aimed at heart muscle in the writeups, but people still take it as a whole-body capsule. systemic whole-body circulating", "legal_class": null }, { "id": 260, "slug": "glandokort", "name": "Glandokort", "aliases": [ "A-17", "adrenal cytomax", "A-17 adrenal bioregulator", "Khavinson adrenal complex", "Glandokort peptide" ], "type": "Peptide", "category": "Organ bioregulators", "goals_use_cases": [ "stress / adrenal-fatigue talk (community)", "energy / burnout narratives", "longevity / organ-bioregulator calendars", "hormone-axis neighbor stacks" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "glandokort", "glandokort peptide", "a-17 bioregulator", "a17 adrenal", "glandokort dosage", "adrenal cytomax", "stress / adrenal-fatigue talk (community)", "energy / burnout narratives", "longevity / organ-bioregulator calendars", "hormone-axis neighbor stacks" ], "feel_search": [ "stress / adrenal-fatigue talk (community)", "energy / burnout narratives", "longevity / organ-bioregulator calendars", "hormone-axis neighbor stacks" ], "summary": "Glandokort is an adrenal-tissue peptide extract sold in capsules; people look it up for stress and low-energy complaints.", "search_blob": "glandokort glandokort a-17 adrenal cytomax a-17 adrenal bioregulator khavinson adrenal complex glandokort peptide glandokort glandokort peptide a-17 bioregulator a17 adrenal glandokort dosage adrenal cytomax stress / adrenal-fatigue talk (community) energy / burnout narratives longevity / organ-bioregulator calendars hormone-axis neighbor stacks stress / adrenal-fatigue talk (community) energy / burnout narratives longevity / organ-bioregulator calendars hormone-axis neighbor stacks stress / adrenal-fatigue talk (community) energy / burnout narratives longevity / organ-bioregulator calendars hormone-axis neighbor stacks glandokort is an adrenal-tissue peptide extract sold in capsules; people look it up for stress and low-energy complaints. glandokort is a peptide people look up for energy. one capsule sped up mind and heart; two capsules caused uncomfortable anxiety, and the user stopped quickly. not pregnenolone, not hpa-axis bloodwork, not a license to stop prescribed steroids. organ bioregulators peptide systemic aimed at adrenal tissue in the writeups, but people still take it as a whole-body capsule. systemic whole-body circulating", "legal_class": null }, { "id": 261, "slug": "taxorest", "name": "Taxorest", "aliases": [ "A-19", "lung cytomax", "A-19 lung bioregulator", "bronchial cytomax", "Khavinson lung complex", "Taxorest peptide" ], "type": "Peptide", "category": "Organ bioregulators", "goals_use_cases": [ "respiratory / lung-support talk", "chronic bronchitis adjunct talk", "longevity / organ-bioregulator calendars", "breathing-comfort narratives" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "taxorest", "taxorest peptide", "a-19 bioregulator", "a19 lung", "taxorest dosage", "taxorest vs chonluten", "respiratory / lung-support talk", "chronic bronchitis adjunct talk", "longevity / organ-bioregulator calendars", "breathing-comfort narratives" ], "feel_search": [ "respiratory / lung-support talk", "chronic bronchitis adjunct talk", "longevity / organ-bioregulator calendars", "breathing-comfort narratives" ], "summary": "Taxorest (A-19) is a bronchial-mucosa-derived peptide mixture marketed for respiratory support, distinct from Chonluten and Bronchogen.", "search_blob": "taxorest taxorest a-19 lung cytomax a-19 lung bioregulator bronchial cytomax khavinson lung complex taxorest peptide taxorest taxorest peptide a-19 bioregulator a19 lung taxorest dosage taxorest vs chonluten respiratory / lung-support talk chronic bronchitis adjunct talk longevity / organ-bioregulator calendars breathing-comfort narratives respiratory / lung-support talk chronic bronchitis adjunct talk longevity / organ-bioregulator calendars breathing-comfort narratives respiratory / lung-support talk chronic bronchitis adjunct talk longevity / organ-bioregulator calendars breathing-comfort narratives taxorest (a-19) is a bronchial-mucosa-derived peptide mixture marketed for respiratory support, distinct from chonluten and bronchogen. one recovery blogger reported easier breathing while switching among taxorest, chonluten and lunguard and also using kpv. taxorest is an oral peptide people look up for breath. the 2-year, 3\u00d7/year x log is the loudest personal claim. not a rescue inhaler, steroid, oxygen, or antifibrotic. organ bioregulators peptide systemic systemic oral animal-lung tissue peptide extract sold as organ-targeted support; human efficacy and pharmacokinetics remain very thin. systemic whole-body circulating", "legal_class": null }, { "id": 262, "slug": "zhenoluten", "name": "Zhenoluten", "aliases": [ "A-15", "Jenoluten", "ovary cytomax", "A-15 ovary bioregulator", "Khavinson ovary complex", "Zhenoluten peptide" ], "type": "Peptide", "category": "Organ bioregulators", "goals_use_cases": [ "female reproductive / ovarian talk", "perimenopause / cycle-regularity narratives", "longevity / organ-bioregulator calendars" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "zhenoluten", "jenoluten", "zhenoluten peptide", "a-15 bioregulator", "a15 ovary", "zhenoluten dosage", "female reproductive / ovarian talk", "perimenopause / cycle-regularity narratives", "longevity / organ-bioregulator calendars" ], "feel_search": [ "female reproductive / ovarian talk", "perimenopause / cycle-regularity narratives", "longevity / organ-bioregulator calendars" ], "summary": "Zhenoluten, also spelled Jenoluten, is an ovarian-tissue-derived peptide mixture marketed for ovarian and menstrual-cycle support.", "search_blob": "zhenoluten zhenoluten a-15 jenoluten ovary cytomax a-15 ovary bioregulator khavinson ovary complex zhenoluten peptide zhenoluten jenoluten zhenoluten peptide a-15 bioregulator a15 ovary zhenoluten dosage female reproductive / ovarian talk perimenopause / cycle-regularity narratives longevity / organ-bioregulator calendars female reproductive / ovarian talk perimenopause / cycle-regularity narratives longevity / organ-bioregulator calendars female reproductive / ovarian talk perimenopause / cycle-regularity narratives longevity / organ-bioregulator calendars zhenoluten, also spelled jenoluten, is an ovarian-tissue-derived peptide mixture marketed for ovarian and menstrual-cycle support. one fertility-forum user reported stronger nails but uncertain, temporary changes in follicle counts while trying several treatments. zhenoluten is a peptide people look up for longevity. vendor and influencer pages claim more predictable cycles, fewer hot-flash stories. organ bioregulators peptide systemic aimed at ovarian tissue in the writeups, but people still take it as a whole-body capsule. systemic whole-body circulating", "legal_class": null }, { "id": 263, "slug": "bonothyrk", "name": "Bonothyrk", "aliases": [ "A-21", "Bonotirk", "parathyroid cytomax", "A-21 parathyroid bioregulator", "Khavinson parathyroid complex", "Bonothyrk peptide" ], "type": "Peptide", "category": "Organ bioregulators", "goals_use_cases": [ "bone / calcium-balance talk", "parathyroid-support narratives", "longevity / organ-bioregulator calendars" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "bonothyrk", "bonotirk", "bonothyrk peptide", "a-21 bioregulator", "a21 parathyroid", "bonothyrk dosage", "bone / calcium-balance talk", "parathyroid-support narratives", "longevity / organ-bioregulator calendars" ], "feel_search": [ "bone / calcium-balance talk", "parathyroid-support narratives", "longevity / organ-bioregulator calendars" ], "summary": "Bonothyrk (Bonotirk) is a parathyroid-derived peptide complex sold as a bioregulator, distinct from PTH hormone drugs or calcium supplements.", "search_blob": "bonothyrk bonothyrk a-21 bonotirk parathyroid cytomax a-21 parathyroid bioregulator khavinson parathyroid complex bonothyrk peptide bonothyrk bonotirk bonothyrk peptide a-21 bioregulator a21 parathyroid bonothyrk dosage bone / calcium-balance talk parathyroid-support narratives longevity / organ-bioregulator calendars bone / calcium-balance talk parathyroid-support narratives longevity / organ-bioregulator calendars bone / calcium-balance talk parathyroid-support narratives longevity / organ-bioregulator calendars bonothyrk (bonotirk) is a parathyroid-derived peptide complex sold as a bioregulator, distinct from pth hormone drugs or calcium supplements. the inspected reddit post is product promotion. it supplies no firsthand symptom change, onset or treatment follow-up. bonothyrk is sold for bone/calcium-support goals as an oral a-21 parathyroid-tissue peptide complex. the inspected reddit item was promotional and did not report personal use. thyreogen is thyroid. bonothyrk is parathyroid. different glands, both \u201cthyr-\u201d in the catalog. organ bioregulators peptide systemic aimed at parathyroid tissue in the writeups, but people still take it as a whole-body capsule. systemic whole-body circulating", "legal_class": null }, { "id": 264, "slug": "amlexanox", "name": "Amlexanox", "aliases": [ "Aphthasol", "TBK1 IKK\u03b5 inhibitor", "CHX 3673", "amlexanox oral" ], "type": "Non-peptide", "category": "Metabolic & longevity adjacents", "goals_use_cases": [ "fat loss / recomp talk", "insulin-sensitivity talk", "NAFLD / liver-fat curiosity", "inflammation-metabolic research" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "amlexanox", "amlexanox dosage", "aphthasol oral", "tbk1 inhibitor", "amlexanox fat loss", "amlex", "fat loss / recomp talk", "insulin-sensitivity talk", "nafld / liver-fat curiosity", "inflammation-metabolic research" ], "feel_search": [ "fat loss / recomp talk", "insulin-sensitivity talk", "nafld / liver-fat curiosity", "inflammation-metabolic research" ], "summary": "Amlexanox is a small-molecule drug once used in canker-sore paste and now discussed for inflammation, metabolism and mast-cell symptoms.", "search_blob": "amlexanox amlexanox aphthasol tbk1 ikk\u03b5 inhibitor chx 3673 amlexanox oral amlexanox amlexanox dosage aphthasol oral tbk1 inhibitor amlexanox fat loss amlex fat loss / recomp talk insulin-sensitivity talk nafld / liver-fat curiosity inflammation-metabolic research fat loss / recomp talk insulin-sensitivity talk nafld / liver-fat curiosity inflammation-metabolic research fat loss / recomp talk insulin-sensitivity talk nafld / liver-fat curiosity inflammation-metabolic research amlexanox is a small-molecule drug once used in canker-sore paste and now discussed for inflammation, metabolism and mast-cell symptoms. an mcas user reports no benefit over weeks and later retracts their initial claim that amlexanox caused sedation after stopping and restarting it. amlexanox is an oral compound people look up for fat loss. 3\u20135 week \u201cclothes slightly looser / midsection\u201d logs on stable calories; a chunk feel nothing. forums describe a slow lean over weeks, maybe warmer training, not clen jitter. metabolic & longevity adjacents non-peptide systemic whole-body oral capsule in the fat-loss talk \u2014 not a mouth-ulcer smear. systemic whole-body circulating", "legal_class": null }, { "id": 265, "slug": "c60", "name": "C60", "aliases": [ "carbon 60", "fullerene", "buckminsterfullerene", "buckyballs", "C60-OO", "C60 olive oil" ], "type": "Non-peptide", "category": "Longevity & cellular energy", "goals_use_cases": [ "longevity / antioxidant talk", "C60-in-olive-oil biohack", "mitochondrial / energy narratives" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "c60", "c-60", "carbon 60", "fullerene", "buckyballs", "c60 olive oil", "c60 dosage", "buckminsterfullerene", "longevity / antioxidant talk", "mitochondrial / energy narratives", "c60-in-olive-oil biohack" ], "feel_search": [ "longevity / antioxidant talk", "mitochondrial / energy narratives", "c60-in-olive-oil biohack" ], "summary": "C60 is a 60-carbon fullerene molecule, commonly discussed in olive-oil preparations for experimental longevity use.", "search_blob": "c60 c60 carbon 60 fullerene buckminsterfullerene buckyballs c60-oo c60 olive oil c60 c-60 carbon 60 fullerene buckyballs c60 olive oil c60 dosage buckminsterfullerene longevity / antioxidant talk mitochondrial / energy narratives c60-in-olive-oil biohack longevity / antioxidant talk c60-in-olive-oil biohack mitochondrial / energy narratives longevity / antioxidant talk mitochondrial / energy narratives c60-in-olive-oil biohack c60 is a 60-carbon fullerene molecule, commonly discussed in olive-oil preparations for experimental longevity use. one long-term user reports no appreciable effect; another describes better cardio and minor changes while rejecting cure-all claims. these accounts do not measure lifespan. c60 is an oral compound people look up for longevity. r/nootropics-era gym and \u201cclean energy\u201d posts. not olive oil as the active, not graphene, not a mitochondrial peptide. longevity & cellular energy non-peptide systemic whole-body oral oil in the longevity talk \u2014 not a peptide pin. systemic whole-body circulating", "legal_class": null }, { "id": 266, "slug": "zinc-l-carnosine", "name": "Zinc L-carnosine", "aliases": [ "polaprezinc", "PepZin GI", "zinc carnosine", "ZnC", "zinc-carnosine" ], "type": "Non-peptide", "category": "Gut & inflammation peptides", "goals_use_cases": [ "gut lining / gastritis talk", "leaky-gut / permeability narratives", "ulcer-adjunct discussion" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Mixed", "misspellings_search_terms": [ "zinc l-carnosine", "zinc carnosine", "pepzin gi", "polaprezinc", "znc", "zinc-carnosine dosage", "gastritis flare", "pepzin", "empty stomach", "gut lining", "leaky gut", "zinc burn", "not bpc" ], "feel_search": [ "gastritis flare", "pepzin", "empty stomach", "gut lining", "leaky gut", "zinc burn", "not bpc" ], "summary": "Zinc L-carnosine, or polaprezinc, is a zinc\u2013carnosine complex used in gastric-mucosal treatment and sold in gut-health supplements.", "search_blob": "zinc l-carnosine zinc-l-carnosine polaprezinc pepzin gi zinc carnosine znc zinc-carnosine zinc l-carnosine zinc carnosine pepzin gi polaprezinc znc zinc-carnosine dosage gastritis flare pepzin empty stomach gut lining leaky gut zinc burn not bpc gut lining / gastritis talk leaky-gut / permeability narratives ulcer-adjunct discussion gastritis flare pepzin empty stomach gut lining leaky gut zinc burn not bpc zinc l-carnosine, or polaprezinc, is a zinc\u2013carnosine complex used in gastric-mucosal treatment and sold in gut-health supplements. one person described less stomach pain and reflux while continuing other treatment; another reported an immediate flare and stopped. zinc l-carnosine is an oral compound people look up for gut. some call it the thing that let them eat again; some flare. 75 mg twice a day of the chelate is the us bottle. not a peptide pin. elemental zinc still counts. gut & inflammation peptides non-peptide mixed sold as a gut-lining chew \u2014 zinc still circulates, but the talk is the stomach wall, not a body-wide zinc dump. mixed local systemic", "legal_class": null }, { "id": 267, "slug": "tributyrin", "name": "Tributyrin", "aliases": [ "glyceryl tributyrate", "CoreBiome", "butyrate triglyceride", "tributyrin butyrate" ], "type": "Non-peptide", "category": "Gut & inflammation peptides", "goals_use_cases": [ "gut lining / butyrate talk", "SIBO / dysbiosis adjunct narratives", "gut-mood n=1 logs" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Emerging", "reach": "Mixed", "misspellings_search_terms": [ "tributyrin", "tributyrin dosage", "corebiome", "butyrate triglyceride", "glyceryl tributyrate", "tributyrin vs sodium butyrate", "gut lining / butyrate talk", "sibo / dysbiosis adjunct narratives", "gut-mood n=1 logs" ], "feel_search": [ "gut lining / butyrate talk", "sibo / dysbiosis adjunct narratives", "gut-mood n=1 logs" ], "summary": "Tributyrin joins three butyrate molecules to glycerol and is sold as an oral butyrate-delivering compound for gut-related interests.", "search_blob": "tributyrin tributyrin glyceryl tributyrate corebiome butyrate triglyceride tributyrin butyrate tributyrin tributyrin dosage corebiome butyrate triglyceride glyceryl tributyrate tributyrin vs sodium butyrate gut lining / butyrate talk sibo / dysbiosis adjunct narratives gut-mood n=1 logs gut lining / butyrate talk sibo / dysbiosis adjunct narratives gut-mood n=1 logs gut lining / butyrate talk sibo / dysbiosis adjunct narratives gut-mood n=1 logs tributyrin joins three butyrate molecules to glycerol and is sold as an oral butyrate-delivering compound for gut-related interests. one person briefly felt clearer and better, then developed anxiety, irritability, insomnia and diarrhea and stopped. tributyrin is an oral compound for gut. r/sibosuccessstories \u2014 tolerated perfectly after other butyrates failed; more bms in days; inflammation \u201cdevastating \u2192 manageable.\u201d not a probiotic, not rifaximin, not a peptide. gut & inflammation peptides non-peptide mixed swallowed for the colon \u2014 some still talk whole-body fog and mood when the gut shifts. mixed local systemic", "legal_class": null }, { "id": 268, "slug": "hyaluronic-acid", "name": "Hyaluronic acid", "aliases": [ "HA", "hyaluronan", "oral HA", "sodium hyaluronate", "hyaluronic acid pills" ], "type": "Non-peptide", "category": "Skin, hair & tissue remodeling", "goals_use_cases": [ "skin hydration / wrinkle talk", "joint comfort / OA-adjunct talk", "oral vs injection HA" ], "delivery_methods": [ "oral", "topical" ], "discussion_popularity": "Medium", "reach": "Mixed", "misspellings_search_terms": [ "hyaluronic acid", "hyaluronic acid dosage", "oral ha", "hyaluronan", "sodium hyaluronate", "ha pills", "hyaluronic acid joints", "120 mg", "knee shot", "serum dew", "not filler", "tret dryness", "blueprint", "mw fight" ], "feel_search": [ "oral ha", "120 mg", "knee shot", "serum dew", "not filler", "tret dryness", "blueprint", "mw fight" ], "summary": "Hyaluronic acid is a water-binding sugar polymer; oral supplements, skin serums and joint injections are different formulations used for hydration or joint symptoms.", "search_blob": "hyaluronic acid hyaluronic-acid ha hyaluronan oral ha sodium hyaluronate hyaluronic acid pills hyaluronic acid hyaluronic acid dosage oral ha hyaluronan sodium hyaluronate ha pills hyaluronic acid joints 120 mg knee shot serum dew not filler tret dryness blueprint mw fight skin hydration / wrinkle talk joint comfort / oa-adjunct talk oral vs injection ha oral ha 120 mg knee shot serum dew not filler tret dryness blueprint mw fight hyaluronic acid is a water-binding sugar polymer; oral supplements, skin serums and joint injections are different formulations used for hydration or joint symptoms. oral users report anything from improved skin hydration over weeks to no visible change after a year. that differs from the immediate surface feel of a serum. hyaluronic acid is an oral compound people look up for skin. people report high-mw for hydration/joints, low-mw for wrinkles. this card is mostly the 120 mg oral talk. don\u2019t copy a syringe into a swallow. skin, hair & tissue remodeling non-peptide mixed pills go through the gut; the other ha jobs are a serum or a knee needle \u2014 don\u2019t mix those stories. mixed local systemic", "legal_class": null }, { "id": 269, "slug": "myo-inositol-d-chiro-inositol", "name": "Myo-inositol / D-chiro-inositol", "aliases": [ "inositol", "myo-inositol", "D-chiro-inositol", "40:1 inositol", "MI/DCI", "inositol PCOS" ], "type": "Non-peptide", "category": "Metabolic & longevity adjacents", "goals_use_cases": [ "PCOS / cycle-regularity talk", "insulin-sensitivity talk", "sleep / Huberman-night add-on" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "inositol", "myo-inositol", "myoinositol", "d-chiro-inositol", "d chiro inositol", "40:1 inositol", "inositol pcos", "inositol dosage", "pcos / cycle-regularity talk", "insulin-sensitivity talk", "sleep / huberman-night add-on" ], "feel_search": [ "pcos / cycle-regularity talk", "insulin-sensitivity talk", "sleep / huberman-night add-on" ], "summary": "Myo-inositol and D-chiro-inositol are related nutrient compounds, often sold together in a 40:1 blend for PCOS and metabolic goals.", "search_blob": "myo-inositol / d-chiro-inositol myo-inositol-d-chiro-inositol inositol myo-inositol d-chiro-inositol 40:1 inositol mi/dci inositol pcos inositol myo-inositol myoinositol d-chiro-inositol d chiro inositol 40:1 inositol inositol pcos inositol dosage pcos / cycle-regularity talk insulin-sensitivity talk sleep / huberman-night add-on pcos / cycle-regularity talk insulin-sensitivity talk sleep / huberman-night add-on pcos / cycle-regularity talk insulin-sensitivity talk sleep / huberman-night add-on myo-inositol and d-chiro-inositol are related nutrient compounds, often sold together in a 40:1 blend for pcos and metabolic goals. reports describe changes in cravings, sleepiness or pms over weeks; some users report dizziness or stomach upset. menstrual-cycle changes are tracked over months. myo-inositol / d-chiro-inositol is an oral compound people look up for pcos. first 30-day cycle, less anxiety, fewer cravings. not metformin, not birth control, not a fertility drug label. metabolic & longevity adjacents non-peptide systemic whole-body oral powder \u2014 pcos people take grams; sleep-stack people take a fraction of that. systemic whole-body circulating", "legal_class": null }, { "id": 270, "slug": "magnesium-l-threonate", "name": "Magnesium L-threonate", "aliases": [ "Magtein", "MgT", "magnesium threonate", "L-threonate magnesium" ], "type": "Non-peptide", "category": "Cognitive research compounds", "goals_use_cases": [ "sleep / Huberman-night stack", "cognition / memory talk", "vs magnesium glycinate" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "magnesium l-threonate", "magnesium threonate", "magtein", "mag l threonate", "magnesium threonate dosage", "huberman magnesium", "sleep / huberman-night stack", "cognition / memory talk", "vs magnesium glycinate" ], "feel_search": [ "sleep / huberman-night stack", "cognition / memory talk", "vs magnesium glycinate" ], "summary": "Magnesium L-threonate is a magnesium salt sold as Magtein, discussed for sleep and cognition; compound weight differs from elemental magnesium.", "search_blob": "magnesium l-threonate magnesium-l-threonate magtein mgt magnesium threonate l-threonate magnesium magnesium l-threonate magnesium threonate magtein mag l threonate magnesium threonate dosage huberman magnesium sleep / huberman-night stack cognition / memory talk vs magnesium glycinate sleep / huberman-night stack cognition / memory talk vs magnesium glycinate sleep / huberman-night stack cognition / memory talk vs magnesium glycinate magnesium l-threonate is a magnesium salt sold as magtein, discussed for sleep and cognition; compound weight differs from elemental magnesium. some feel sleepy, others notice little or gi discomfort. it is not reliably sedating: one long-time user described a few hours of mental energy and occasional overstimulation. magnesium l-threonate is an oral compound people look up for memory. \u201cmemory sharper, sleep kinda felt better, trackers meh.\u201d huberman clips get quoted as 145 mg elemental vs 200\u2013400 mg of salt vs 2 g magtein in the trial. those are not the same number. cognitive research compounds non-peptide systemic oral magnesium salt \u2014 marketed for brain/cognition rather than the muscle-relaxation pitch associated with glycinate. systemic whole-body circulating", "legal_class": null }, { "id": 271, "slug": "gt20029", "name": "GT20029", "aliases": [ "GT-20029", "Kintor GT20029", "topical AR PROTAC", "GT 20029", "androgen receptor degrader topical", "Kintor hair PROTAC" ], "type": "Non-peptide", "category": "Skin, hair & tissue remodeling", "goals_use_cases": [ "skin/hair", "androgenetic alopecia / topical AR degradation", "finasteride-avoid topical add-on", "pyrilutamide / RU-58841 comparison", "twice-weekly scalp routine talk" ], "delivery_methods": [ "topical" ], "discussion_popularity": "High", "reach": "Local", "misspellings_search_terms": [ "gt20029", "gt-20029", "gt 20029", "kintor protac", "ar degrader hair", "gt20029 topical", "hair", "scalp", "dht", "androgen receptor", "tressless", "new fin", "shedding" ], "feel_search": [ "hair", "scalp", "dht", "androgen receptor", "tressless", "new fin", "shedding" ], "summary": "GT20029 is an experimental topical androgen-receptor degrader being studied for pattern hair loss; it works differently from finasteride.", "search_blob": "gt20029 gt20029 gt-20029 kintor gt20029 topical ar protac gt 20029 androgen receptor degrader topical kintor hair protac gt20029 gt-20029 gt 20029 kintor protac ar degrader hair gt20029 topical hair scalp dht androgen receptor tressless new fin shedding skin/hair androgenetic alopecia / topical ar degradation finasteride-avoid topical add-on pyrilutamide / ru-58841 comparison twice-weekly scalp routine talk hair scalp dht androgen receptor tressless new fin shedding gt20029 is an experimental topical androgen-receptor degrader being studied for pattern hair loss; it works differently from finasteride. topical trial participants reported dryness, itching, rash, peeling or local discomfort. verified long-term consumer experience is sparse, so a typical diy response is unclear. gt20029 is a topical compound people look up for hair. the \u201cnew fin\u201d topical on r/tressless \u2014 degrade the androgen receptor on the scalp instead of shutting down dht everywhere. phase 2 was 12 weeks. twice-weekly 1% is the convenience screenshot. not a peptide. skin, hair & tissue remodeling non-peptide local local \u2014 a scalp liquid. not a whole-body anti-androgen pill. local site pin topical", "legal_class": null }, { "id": 272, "slug": "pp405", "name": "PP405", "aliases": [ "PP-405", "Suvomipic", "JXL069", "Pelage PP405", "PP 405", "JXL-069", "PP405-3HP", "MPC inhibitor hair gel" ], "type": "Non-peptide", "category": "Skin, hair & tissue remodeling", "goals_use_cases": [ "skin/hair", "androgenetic alopecia / dormant follicle talk", "minoxidil-alternative mechanism", "terminal hair from bald spots (discussed)", "gray-market identity fights" ], "delivery_methods": [ "topical" ], "discussion_popularity": "High", "reach": "Local", "misspellings_search_terms": [ "pp405", "pp-405", "suvomipic", "jxl069", "jxl-069", "pelage hair", "pp405 3hp", "dormant follicle gel", "hair", "bald", "dormant follicle", "tressless", "density" ], "feel_search": [ "hair", "bald", "dormant follicle", "tressless", "jxl069", "suvomipic", "density" ], "summary": "PP405 is an investigational topical small molecule that inhibits the mitochondrial pyruvate carrier, studied for hair regrowth.", "search_blob": "pp405 pp405 pp-405 suvomipic jxl069 pelage pp405 pp 405 jxl-069 pp405-3hp mpc inhibitor hair gel pp405 pp-405 suvomipic jxl069 jxl-069 pelage hair pp405 3hp dormant follicle gel hair bald dormant follicle tressless density skin/hair androgenetic alopecia / dormant follicle talk minoxidil-alternative mechanism terminal hair from bald spots (discussed) gray-market identity fights hair bald dormant follicle tressless jxl069 suvomipic density pp405 is an investigational topical small molecule that inhibits the mitochondrial pyruvate carrier, studied for hair regrowth. diy jxl069 reports range from early hair-quality changes to no meaningful regrowth; those products are not authenticated as pelage's pp405 gel. pp405 is a topical hair compound in the reviewed secondary comparison, and who\u2019s entry names neither jxl069 nor pp405. people report early hair-quality changes or nothing. the short phase 2a headline was a responder subgroup, not a 31% mean density gain. most online \u201cpp405\u201d is not pelage\u2019s gel. skin, hair & tissue remodeling non-peptide local local \u2014 a scalp gel. not a whole-body hormone. local site pin topical", "legal_class": null }, { "id": 273, "slug": "4-dma-78-dhf", "name": "4\u2032-DMA-7,8-DHF", "aliases": [ "4DMA", "Eutropoflavin", "4-DMA-7,8-DHF", "4-DMA", "4\u2032-dimethylamino-7,8-dihydroxyflavone", "4'-DMA-7,8-DHF", "7,8-DHF analog", "TrkB agonist flavone" ], "type": "Non-peptide", "category": "Cognitive research compounds", "goals_use_cases": [ "cognition", "mood / anhedonia talk", "BDNF / TrkB narratives", "sleep disruption (side)", "focus without stimulant feel (discussed)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "4dma", "4-dma", "4 dma", "eutropoflavin", "4-dma-7,8-dhf", "78dhf", "7,8 dhf analog", "trkb agonist", "mood", "focus", "brain fog", "sleep", "bdnf", "anhedonia", "social" ], "feel_search": [ "mood", "focus", "brain fog", "sleep", "bdnf", "anhedonia", "social" ], "summary": "4\u2032-DMA-7,8-DHF is a 7,8-DHF derivative sold as a research nootropic for mood and focus.", "search_blob": "4\u2032-dma-7,8-dhf 4-dma-78-dhf 4dma eutropoflavin 4-dma-7,8-dhf 4-dma 4\u2032-dimethylamino-7,8-dihydroxyflavone 4'-dma-7,8-dhf 7,8-dhf analog trkb agonist flavone 4dma 4-dma 4 dma eutropoflavin 4-dma-7,8-dhf 78dhf 7,8 dhf analog trkb agonist mood focus brain fog sleep bdnf anhedonia social cognition mood / anhedonia talk bdnf / trkb narratives sleep disruption (side) focus without stimulant feel (discussed) mood focus brain fog sleep bdnf anhedonia social 4\u2032-dma-7,8-dhf is a 7,8-dhf derivative sold as a research nootropic for mood and focus. one sublingual user describes a subtle early shift, stronger focus and stimulation about four hours later, then trouble sleeping and next-day exhaustion. 4\u2032-dma-7,8-dhf is an oral compound people look up for focus. easier attention without a racetam burn. 8\u201310 mg morning appears in capsule notes. sleep disruption can extend late; people describe varied on/off patterns. cognitive research compounds non-peptide systemic systemic flavone discussed orally or sublingually; not a peptide injection. systemic whole-body circulating", "legal_class": null }, { "id": 274, "slug": "dim", "name": "DIM", "aliases": [ "Diindolylmethane", "3,3'-diindolylmethane", "BioResponse DIM", "3,3\u2019-Diindolylmethane", "I3C metabolite (discussed)", "cruciferous estrogen supplement" ], "type": "Non-peptide", "category": "Hormone modulators", "goals_use_cases": [ "estrogen metabolism talk", "TRT / high-E2 folklore", "hormonal acne", "hair / estrogen-dominance stacks", "PMS / women\u2019s hormone talk" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "dim", "diindolylmethane", "di-indolylmethane", "bioresponse dim", "i3c dim", "estrogen blocker dim", "estrogen", "e2", "acne", "trt", "pms", "water weight", "headache" ], "feel_search": [ "estrogen", "e2", "acne", "trt", "pms", "water weight", "headache" ], "summary": "DIM (3,3\u2032-diindolylmethane) is a crucifer-derived compound sold as a supplement and discussed for estrogen metabolism and acne.", "search_blob": "dim dim diindolylmethane 3,3'-diindolylmethane bioresponse dim 3,3\u2019-diindolylmethane i3c metabolite (discussed) cruciferous estrogen supplement dim diindolylmethane di-indolylmethane bioresponse dim i3c dim estrogen blocker dim estrogen e2 acne trt pms water weight headache estrogen metabolism talk trt / high-e2 folklore hormonal acne hair / estrogen-dominance stacks pms / women\u2019s hormone talk estrogen e2 acne trt pms water weight headache dim (3,3\u2032-diindolylmethane) is a crucifer-derived compound sold as a supplement and discussed for estrogen metabolism and acne. a pcos user describes fewer breakouts in week three and clearer skin by week four. that does not show that serum estradiol fell or that dim acts like an aromatase inhibitor. dim is an oral supplement people look up for estrogen. eat broccoli in a pill to move estrogen. 100\u2013200 mg with food. logs go both ways: e2 down a little, unchanged, or crashed. hormone modulators non-peptide systemic systemic oral \u2014 a capsule with food, not a scalp liquid or an ai pill. systemic whole-body circulating", "legal_class": null }, { "id": 275, "slug": "methylcobalamin", "name": "Methylcobalamin", "aliases": [ "Methyl B12", "Vitamin B12", "B12", "cyanocobalamin", "MeCbl", "Vitamin B12 (methyl form)", "cobalamin", "cyanocobalamin (often compounded instead)", "hydroxocobalamin (clinic cousin)", "adenosylcobalamin (discussed)" ], "type": "Non-peptide", "category": "Longevity & cellular energy", "goals_use_cases": [ "energy / fatigue talk", "GLP-1 compounding add-on", "methylation / MTHFR folklore", "neuropathy talk", "vegan / metformin B12 gap" ], "delivery_methods": [ "oral", "intramuscular", "subcutaneous" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "methylcobalamin", "methyl cobalamin", "methyl b12", "b12", "b-12", "cyanocobalamin", "mecbl", "vitamin b12", "energy", "fatigue", "methylation", "neuropathy", "glp", "pink urine" ], "feel_search": [ "energy", "fatigue", "b12", "methylation", "neuropathy", "glp", "pink urine" ], "summary": "Methylcobalamin is one form of vitamin B12, used to correct deficiency and discussed for energy; it is not a general stimulant or interchangeable with NAD+.", "search_blob": "methylcobalamin methylcobalamin methyl b12 vitamin b12 b12 cyanocobalamin mecbl vitamin b12 (methyl form) cobalamin cyanocobalamin (often compounded instead) hydroxocobalamin (clinic cousin) adenosylcobalamin (discussed) methylcobalamin methyl cobalamin methyl b12 b12 b-12 cyanocobalamin mecbl vitamin b12 energy fatigue methylation neuropathy glp pink urine energy / fatigue talk glp-1 compounding add-on methylation / mthfr folklore neuropathy talk vegan / metformin b12 gap energy fatigue b12 methylation neuropathy glp pink urine methylcobalamin is one form of vitamin b12, used to correct deficiency and discussed for energy; it is not a general stimulant or interchangeable with nad+. some notice little fatigue improvement; others report anxiety or mood changes after hours or weeks. a 'b12 buzz' does not establish deficiency or show that the product is helping. methylcobalamin is a compound people look up for energy. some feel a b12 buzz; many feel nothing because they were never deficient. standalone tablets and injections, and b12 inside a combined glp product, are different records. a glp dose or draw volume alone does not reveal the methylcobalamin amount. longevity & cellular energy non-peptide systemic systemic \u2014 a vitamin you swallow or pin. not a local healing peptide. systemic whole-body circulating", "legal_class": null }, { "id": 276, "slug": "ketoconazole", "name": "Ketoconazole", "aliases": [ "Nizoral", "keto shampoo", "ketoconazole 1%", "ketoconazole 2%", "Nizoral A-D", "topical keto" ], "type": "Non-peptide", "category": "Skin, hair & tissue remodeling", "goals_use_cases": [ "skin/hair", "dandruff / seborrheic dermatitis", "androgenetic alopecia add-on", "scalp oil / DHT folklore", "min/fin stack staple" ], "delivery_methods": [ "topical" ], "discussion_popularity": "High", "reach": "Local", "misspellings_search_terms": [ "ketoconazole", "nizoral", "keto shampoo", "ketokonazole", "nizorol", "2% keto", "dandruff", "itch", "hair", "oily scalp", "dry hair" ], "feel_search": [ "dandruff", "itch", "hair", "nizoral", "oily scalp", "dry hair" ], "summary": "Ketoconazole is an antifungal, usually discussed here as scalp shampoo for dandruff and itching or as a hair-loss adjunct; oral tablets are different.", "search_blob": "ketoconazole ketoconazole nizoral keto shampoo ketoconazole 1% ketoconazole 2% nizoral a-d topical keto ketoconazole nizoral keto shampoo ketokonazole nizorol 2% keto dandruff itch hair oily scalp dry hair skin/hair dandruff / seborrheic dermatitis androgenetic alopecia add-on scalp oil / dht folklore min/fin stack staple dandruff itch hair nizoral oily scalp dry hair ketoconazole is an antifungal, usually discussed here as scalp shampoo for dandruff and itching or as a hair-loss adjunct; oral tablets are different. scalp users may notice dryness, tightness or irritation first, with flakes becoming quieter over repeated washes. persistent itching or a worsening reaction is also reported. ketoconazole is an oral compound people look up for skin. dry, squeaky, color-fade on dyed hair. 1\u20132%, a few times a week, leave on a few minutes. not the oral liver drug. skin, hair & tissue remodeling non-peptide local local \u2014 a scalp shampoo for hair talk. swallowing keto tablets is a different, systemic drug. local site pin topical", "legal_class": null }, { "id": 277, "slug": "spironolactone", "name": "Spironolactone", "aliases": [ "Spiro", "Aldactone", "spironolactone topical", "topical spiro", "Aldactone hair" ], "type": "Non-peptide", "category": "Skin, hair & tissue remodeling", "goals_use_cases": [ "skin/hair", "female-pattern hair / PCOS acne", "androgen-receptor block (discussed)", "topical anti-androgen DIY", "blood-pressure / potassium caution" ], "delivery_methods": [ "oral", "topical" ], "discussion_popularity": "High", "reach": "Mixed", "misspellings_search_terms": [ "spironolactone", "spiro", "aldactone", "spironolactone topical", "spirolactone", "aldactone hair", "acne", "hair", "pcos", "potassium", "peeing", "breast tenderness", "dizziness" ], "feel_search": [ "acne", "hair", "pcos", "potassium", "peeing", "breast tenderness", "dizziness" ], "summary": "Spironolactone is a prescription aldosterone blocker with antiandrogen activity, also discussed for acne and hair-related concerns.", "search_blob": "spironolactone spironolactone spiro aldactone spironolactone topical topical spiro aldactone hair spironolactone spiro aldactone spironolactone topical spirolactone aldactone hair acne hair pcos potassium peeing breast tenderness dizziness skin/hair female-pattern hair / pcos acne androgen-receptor block (discussed) topical anti-androgen diy blood-pressure / potassium caution acne hair pcos potassium peeing breast tenderness dizziness spironolactone is a prescription aldosterone blocker with antiandrogen activity, also discussed for acne and hair-related concerns. reports include less oily skin and calmer acne, but also dizziness, increased urination, spotting or genital discomfort. spironolactone is an oral compound people look up for skin. people report the women\u2019s hair/acne pill that also happens to be a blood-pressure diuretic. oral 50\u2013100 mg in women\u2019s logs. watch potassium. not a peptide. skin, hair & tissue remodeling non-peptide mixed mixed \u2014 oral is whole-body (women\u2019s hair/acne); topical diy is a scalp experiment. not a peptide. mixed local systemic", "legal_class": null }, { "id": 278, "slug": "tmg", "name": "TMG", "aliases": [ "Betaine", "Trimethylglycine", "betaine anhydrous", "Betaine anhydrous", "TMG betaine", "glycine betaine", "betaine TMG (not betaine HCl)" ], "type": "Non-peptide", "category": "Longevity & cellular energy", "goals_use_cases": [ "endurance", "methylation / homocysteine", "NMN / NR partner", "endurance / power (betaine sports studies)", "liver / fatty-liver adjacency", "GLP-1 / energy stack talk" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "tmg", "trimethylglycine", "betaine", "betaine anhydrous", "tmg betaine", "trimethyl glycine", "betaine hcl", "methylation", "homocysteine", "nmn", "fishy", "endurance", "pump" ], "feel_search": [ "methylation", "homocysteine", "nmn", "fishy", "endurance", "pump" ], "summary": "TMG is trimethylglycine, or betaine anhydrous, discussed for methylation and homocysteine; it differs from betaine HCl.", "search_blob": "tmg tmg betaine trimethylglycine betaine anhydrous betaine anhydrous tmg betaine glycine betaine betaine tmg (not betaine hcl) tmg trimethylglycine betaine betaine anhydrous tmg betaine trimethyl glycine betaine hcl methylation homocysteine nmn fishy endurance pump endurance methylation / homocysteine nmn / nr partner endurance / power (betaine sports studies) liver / fatty-liver adjacency glp-1 / energy stack talk methylation homocysteine nmn fishy endurance pump tmg is trimethylglycine, or betaine anhydrous, discussed for methylation and homocysteine; it differs from betaine hcl. one person described clearer thinking, motivation and more restful sleep, but difficulty sleeping when taking it later. tmg is an oral compound people look up for energy. some notice more pump/heat. 500\u20131000 mg with the nad stack. 2\u20132.5 g is the older sports-betaine camp. not betaine hcl. longevity & cellular energy non-peptide systemic systemic oral \u2014 a powder or capsule. not a pin. systemic whole-body circulating", "legal_class": null }, { "id": 279, "slug": "luteolin", "name": "Luteolin", "aliases": [ "luteolin flavonoid", "CD38 luteolin", "Luteolin flavonoid", "3',4',5,7-tetrahydroxyflavone", "lutolin", "peanut-hull luteolin (discussed)" ], "type": "Non-peptide", "category": "Longevity & cellular energy", "goals_use_cases": [ "focus", "NAD sparing / CD38 talk", "apigenin stack", "mast-cell / histamine folklore", "inflammation discussion", "brain fog / neuroinflammation talk" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "luteolin", "lutolin", "luteolin cd38", "lutein luteolin", "luteolin apigenin", "nad", "cd38", "histamine", "brain fog", "mast cell", "sleepy" ], "feel_search": [ "nad", "cd38", "histamine", "brain fog", "mast cell", "sleepy" ], "summary": "Luteolin is a plant flavonoid sold as a supplement, discussed for histamine-related symptoms, inflammation and experimental NAD-support ideas.", "search_blob": "luteolin luteolin luteolin flavonoid cd38 luteolin luteolin flavonoid 3',4',5,7-tetrahydroxyflavone lutolin peanut-hull luteolin (discussed) luteolin lutolin luteolin cd38 lutein luteolin luteolin apigenin nad cd38 histamine brain fog mast cell sleepy focus nad sparing / cd38 talk apigenin stack mast-cell / histamine folklore inflammation discussion brain fog / neuroinflammation talk nad cd38 histamine brain fog mast cell sleepy luteolin is a plant flavonoid sold as a supplement, discussed for histamine-related symptoms, inflammation and experimental nad-support ideas. reports include clearer thinking or fewer allergy-like symptoms, daytime tiredness, better sleep or restless sleep. different formulations and co-ingredients make the accounts hard to compare. luteolin is an oral compound people look up for focus. less itch, less fog. 100\u2013200 mg in stacks. absorption is the fight. not lutein. longevity & cellular energy non-peptide systemic systemic oral flavonoid \u2014 a swallow. not lutein, not a pin. systemic whole-body circulating", "legal_class": null }, { "id": 280, "slug": "ecnoglutide", "name": "Ecnoglutide", "aliases": [ "XW003", "XW-003", "Sciwind ecnoglutide", "cAMP-biased GLP-1", "ecnoglutide injection" ], "type": "Peptide", "category": "Metabolic / GLP-1 class", "goals_use_cases": [ "fat loss", "appetite control", "type 2 diabetes (trial/label in China)", "GLP-1 pipeline talk", "biased-agonist folklore" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "ecnoglutide", "xw003", "xw-003", "sciwind", "ecnoglutide glp", "biased glp-1", "appetite", "nausea", "food noise", "glp", "china glp-1" ], "feel_search": [ "appetite", "nausea", "food noise", "glp", "china glp-1" ], "summary": "Ecnoglutide (XW003) is a GLP-1 peptide injection developed for type 2 diabetes and weight management.", "search_blob": "ecnoglutide ecnoglutide xw003 xw-003 sciwind ecnoglutide camp-biased glp-1 ecnoglutide injection ecnoglutide xw003 xw-003 sciwind ecnoglutide glp biased glp-1 appetite nausea food noise glp china glp-1 fat loss appetite control type 2 diabetes (trial/label in china) glp-1 pipeline talk biased-agonist folklore appetite nausea food noise glp china glp-1 ecnoglutide (xw003) is a glp-1 peptide injection developed for type 2 diabetes and weight management. the inspected community thread discusses trial news, competition and price. it supplies no firsthand ecnoglutide response or everyday timeline. ecnoglutide is a peptide people look up for fat loss. china t2d and weight-management approvals are the news. 2.4 mg weekly is the obesity chart people paste. thin english n=1s. not reta. metabolic / glp-1 class peptide systemic systemic weekly glp-1 shot \u2014 whole-body appetite, not a site pin. systemic whole-body circulating", "legal_class": null }, { "id": 281, "slug": "trevogrumab", "name": "Trevogrumab", "aliases": [ "REGN1033", "anti-GDF8 antibody", "anti-myostatin mAb COURAGE", "trevogrumab Regeneron" ], "type": "Non-peptide", "category": "Growth factors / muscle", "goals_use_cases": [ "GLP muscle-spare talk", "myostatin inhibition", "lean-mass preservation", "obesity combination trials" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "trevogrumab", "regn1033", "courage antibody", "anti gdf8", "courage trial", "glp muscle spare antibody", "anti myostatin", "regeneron gdf8" ], "feel_search": [ "courage trial", "glp muscle spare antibody", "anti myostatin", "regeneron gdf8" ], "summary": "Trevogrumab is an investigational antibody against myostatin, studied with weight-loss drugs to limit loss of lean mass.", "search_blob": "trevogrumab trevogrumab regn1033 anti-gdf8 antibody anti-myostatin mab courage trevogrumab regeneron trevogrumab regn1033 courage antibody anti gdf8 courage trial glp muscle spare antibody anti myostatin regeneron gdf8 glp muscle-spare talk myostatin inhibition lean-mass preservation obesity combination trials courage trial glp muscle spare antibody anti myostatin regeneron gdf8 trevogrumab is an investigational antibody against myostatin, studied with weight-loss drugs to limit loss of lean mass. the public combination-trial report describes tolerability and body-composition results, without establishing a distinctive everyday sensation. trevogrumab is an investigational antibody people look up for muscle. semaglutide plus this antibody kept more lean mass than semaglutide alone. trial milligrams with semaglutide. not flgr. not a research-vial chart. growth factors / muscle non-peptide systemic systemic anti-myostatin antibody used in obesity combination trials. systemic whole-body circulating", "legal_class": null }, { "id": 282, "slug": "garetosmab", "name": "Garetosmab", "aliases": [ "Pasatru", "REGN2477", "anti-activin A antibody", "garetosmab-grts", "COURAGE triplet antibody" ], "type": "Non-peptide", "category": "Growth factors / muscle", "goals_use_cases": [ "activin A blockade", "GLP muscle-spare talk", "FOP / heterotopic bone talk", "COURAGE triplet" ], "delivery_methods": [ "IV" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "garetosmab", "pasatru", "regn2477", "anti activin a", "courage triplet", "activin antibody", "fop antibody" ], "feel_search": [ "pasatru", "courage triplet", "activin antibody", "fop antibody" ], "summary": "Garetosmab is an activin-A-blocking antibody; biohackers discuss its role in experimental combinations intended to preserve muscle during weight loss.", "search_blob": "garetosmab garetosmab pasatru regn2477 anti-activin a antibody garetosmab-grts courage triplet antibody garetosmab pasatru regn2477 anti activin a courage triplet activin antibody fop antibody activin a blockade glp muscle-spare talk fop / heterotopic bone talk courage triplet pasatru courage triplet activin antibody fop antibody garetosmab is an activin-a-blocking antibody; biohackers discuss its role in experimental combinations intended to preserve muscle during weight loss. there is no established everyday feel profile in the reviewed sources. trial body-composition changes are measurements, and adverse events or stopping treatment are separate outcomes. garetosmab is an anti-activin a monoclonal antibody. fat-mass drop larger than antibody-without-activin arms. people paste it against flgr skip-activin talk. not a research-vial chart. growth factors / muscle non-peptide systemic systemic anti-activin a antibody \u2014 courage triplet and a separate fop approval. systemic whole-body circulating", "legal_class": null }, { "id": 283, "slug": "rusfertide", "name": "Rusfertide", "aliases": [ "MIMRYLO", "PTG-300", "hepcidin mimetic", "rusfertide PV" ], "type": "Peptide", "category": "Hormone modulators", "goals_use_cases": [ "muscle", "polycythemia vera talk", "approved peptide medicine", "polycythemia vera / erythrocytosis talk", "hepcidin / iron regulation", "approved peptide medicine vs gray GLP" ], "delivery_methods": [ "subcutaneous" ], "discussion_popularity": "Emerging", "reach": "Systemic", "misspellings_search_terms": [ "rusfertide", "mimrylo", "ptg-300", "hepcidin peptide", "hepcidin", "polycythemia peptide", "approved peptide" ], "feel_search": [ "mimrylo", "hepcidin", "polycythemia peptide", "approved peptide" ], "summary": "Rusfertide (PTG-300) mimics the iron-regulating hormone hepcidin; it is developed for polycythemia vera, a disorder with too many red blood cells.", "search_blob": "rusfertide rusfertide mimrylo ptg-300 hepcidin mimetic rusfertide pv rusfertide mimrylo ptg-300 hepcidin peptide hepcidin polycythemia peptide approved peptide muscle polycythemia vera talk approved peptide medicine polycythemia vera / erythrocytosis talk hepcidin / iron regulation approved peptide medicine vs gray glp mimrylo hepcidin polycythemia peptide approved peptide rusfertide (ptg-300) mimics the iron-regulating hormone hepcidin; it is developed for polycythemia vera, a disorder with too many red blood cells. the reviewed evidence describes blood-count control and reduced treatment burden in polycythemia vera, rather than a general energy or gym effect. rusfertide is a peptide people look up for polycythemia. labeled hematology follow-up, not a weekday pump. hematology drug. not a gray weight-loss vial. hormone modulators peptide systemic systemic hepcidin-mimetic peptide approved for polycythemia vera erythrocytosis. systemic whole-body circulating", "legal_class": null }, { "id": 284, "slug": "ace-083", "name": "ACE-083", "aliases": [ "ACE083", "local follistatin ligand trap", "Acceleron ACE-083" ], "type": "Peptide", "category": "Growth factors / muscle", "goals_use_cases": [ "local muscle volume", "follistatin-class comparison", "myostatin / activin trap talk" ], "delivery_methods": [ "intramuscular" ], "discussion_popularity": "Emerging", "reach": "Local", "misspellings_search_terms": [ "ace-083", "ace083", "local follistatin trap", "ace 083", "local follistatin", "size without function", "fshd peptide" ], "feel_search": [ "ace 083", "local follistatin", "size without function", "fshd peptide" ], "summary": "ACE-083 is a modified follistatin protein studied by injection into selected muscles to increase local muscle volume.", "search_blob": "ace-083 ace-083 ace083 local follistatin ligand trap acceleron ace-083 ace-083 ace083 local follistatin trap ace 083 local follistatin size without function fshd peptide local muscle volume follistatin-class comparison myostatin / activin trap talk ace 083 local follistatin size without function fshd peptide ace-083 is a modified follistatin protein studied by injection into selected muscles to increase local muscle volume. one forum commenter says they use a product labelled ace-083 but doubts it is genuine. no result or usable onset timeline is provided. ace-083 is a peptide people look up for muscle. trap the brakes locally so the injected muscle can grow. the comparison object for flgr. programs terminated. not a shop pin. growth factors / muscle peptide local local intramuscular follistatin-based ligand trap \u2014 injected muscle, not a weekly systemic shop pin. local site pin topical", "legal_class": null }, { "id": 285, "slug": "mid-35", "name": "MID-35", "aliases": [ "MID35", "myostatin inhibitory D-peptide-35", "MIPE-1686 successor", "retro-inverso myostatin peptide" ], "type": "Peptide", "category": "Growth factors / muscle", "goals_use_cases": [ "muscle", "local myostatin blockade", "comparison to FLGR-242", "research IM peptide" ], "delivery_methods": [ "intramuscular" ], "discussion_popularity": "Emerging", "reach": "Local", "misspellings_search_terms": [ "mid-35", "mid35", "mid 35 peptide", "d-peptide myostatin", "mid 35", "flgr vs mid", "local myostatin peptide" ], "feel_search": [ "mid 35", "d-peptide myostatin", "flgr vs mid", "local myostatin peptide" ], "summary": "MID-35 is an experimental 16-amino-acid D-peptide studied as a myostatin inhibitor for muscle growth in mice.", "search_blob": "mid-35 mid-35 mid35 myostatin inhibitory d-peptide-35 mipe-1686 successor retro-inverso myostatin peptide mid-35 mid35 mid 35 peptide d-peptide myostatin mid 35 flgr vs mid local myostatin peptide muscle local myostatin blockade comparison to flgr-242 research im peptide mid 35 d-peptide myostatin flgr vs mid local myostatin peptide mid-35 is an experimental 16-amino-acid d-peptide studied as a myostatin inhibitor for muscle growth in mice. no human experience report was found in the reviewed sources. mouse muscle measurements do not establish a human feeling, onset or duration. mid-35 is a peptide people look up for muscle. there is no copied human fullness diary. no human milligrams. do not convert mouse im into a weekly subq. growth factors / muscle peptide local local intramuscular d-peptide in mouse muscle work \u2014 not a weekly systemic shop pin. local site pin topical", "legal_class": null }, { "id": 286, "slug": "ashwagandha", "name": "Ashwagandha", "aliases": [ "Withania somnifera", "KSM-66", "Sensoril", "Shoden", "Indian ginseng (marketplace label)", "winter cherry", "withanolides", "ashwaganda (common misspelling)" ], "type": "Non-peptide", "category": "Herbals in hormone discourse", "goals_use_cases": [ "sleep", "stress", "testosterone support (discussed)", "stress / cortisol (discussed)", "anxiety / calm (discussed)", "recovery", "libido (discussed)", "not a SARM" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "ashwaganda", "ashwaghanda", "ashwagandha ksm66", "withania", "sensoril ashwagandha", "ksm-66", "indian ginseng", "calm", "wired at night", "anhedonia", "flat affect", "cortisol", "natural test", "ksm-66 vs sensoril", "liver", "can't sleep", "not a sarm" ], "feel_search": [ "calm", "wired at night", "anhedonia", "flat affect", "cortisol", "natural test", "ksm-66 vs sensoril", "liver", "can't sleep", "not a sarm" ], "summary": "Ashwagandha is the herb Withania somnifera, sold as root or root-and-leaf extracts for stress, sleep and relaxation.", "search_blob": "ashwagandha ashwagandha withania somnifera ksm-66 sensoril shoden indian ginseng (marketplace label) winter cherry withanolides ashwaganda (common misspelling) ashwaganda ashwaghanda ashwagandha ksm66 withania sensoril ashwagandha ksm-66 indian ginseng calm wired at night anhedonia flat affect cortisol natural test ksm-66 vs sensoril liver can't sleep not a sarm sleep stress testosterone support (discussed) stress / cortisol (discussed) anxiety / calm (discussed) recovery libido (discussed) not a sarm calm wired at night anhedonia flat affect cortisol natural test ksm-66 vs sensoril liver can't sleep not a sarm ashwagandha is the herb withania somnifera, sold as root or root-and-leaf extracts for stress, sleep and relaxation. the inspected thread includes calmer mood and early energy alongside anger or depressed mood. extracts and co-use differ, so one response is not predictable. ashwagandha is an oral compound people look up for sleep. diaries describe less evening rumination more often than a stimulant buzz. cortisol rcts are the densest pile. liver-injury and anhedonia diaries are the watch-for. herbals in hormone discourse non-peptide systemic systemic oral root (or root-and-leaf) extract \u2014 sleep, stress, and natural-t talk, not a sarm. systemic whole-body circulating", "legal_class": null }, { "id": 287, "slug": "lions-mane", "name": "Lion's mane", "aliases": [ "Hericium erinaceus", "Yamabushitake", "mushroom coffee lion's mane", "Hericium", "lion's mane mushroom", "lions mane", "hericenones", "erinacines" ], "type": "Non-peptide", "category": "Cognitive research compounds", "goals_use_cases": [ "cognition", "NGF / nerve-growth talk", "focus / word-finding (discussed)", "mood (discussed)", "mushroom coffee stacks", "nerve repair lore (discussed)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "lions mane", "lion mane", "lionsmane", "hericium erinaceus", "yamabushitake", "hericenone", "erinacine", "mushroom coffee", "brain fog", "word finding", "ngf itch", "focus", "nerve growth", "fruiting body vs mycelium" ], "feel_search": [ "brain fog", "word finding", "ngf itch", "mushroom coffee", "focus", "nerve growth", "yamabushitake", "fruiting body vs mycelium" ], "summary": "Lion\u2019s mane is the mushroom Hericium erinaceus, sold as powders and extracts for cognition; fruiting-body and mycelium products are not equivalent.", "search_blob": "lion's mane lions-mane hericium erinaceus yamabushitake mushroom coffee lion's mane hericium lion's mane mushroom lions mane hericenones erinacines lions mane lion mane lionsmane hericium erinaceus yamabushitake hericenone erinacine mushroom coffee brain fog word finding ngf itch focus nerve growth fruiting body vs mycelium cognition ngf / nerve-growth talk focus / word-finding (discussed) mood (discussed) mushroom coffee stacks nerve repair lore (discussed) brain fog word finding ngf itch mushroom coffee focus nerve growth yamabushitake fruiting body vs mycelium lion\u2019s mane is the mushroom hericium erinaceus, sold as powders and extracts for cognition; fruiting-body and mycelium products are not equivalent. many notice little initially; some later report less fog or easier recall, while others remain unchanged. gi upset or itching can appear before any perceived cognitive benefit. lion's mane is an oral compound people look up for cognition. fog lifted after two weeks. mori\u2019s mci chart was ~3 g/day fruiting-body powder. grocery lattes are usually caffeine plus dust. cognitive research compounds non-peptide systemic systemic oral mushroom \u2014 ngf/cognition talk and coffee packets, not a nasal peptide. systemic whole-body circulating", "legal_class": null }, { "id": 288, "slug": "omega-3", "name": "Omega-3 (EPA/DHA)", "aliases": [ "fish oil", "EPA/DHA", "icosapent ethyl talk", "EPA", "DHA", "icosapent ethyl", "Vascepa-class EPA", "krill oil (adjacent)", "algae oil", "omega 3", "n-3 PUFA" ], "type": "Non-peptide", "category": "Performance staples (biohacking overlap)", "goals_use_cases": [ "triglycerides", "recovery", "inflammation talk", "mood (discussed)", "heart-risk discussion", "omega-3 index", "rancid oil watch-for" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "omega3", "omega 3", "fishoil", "fish oil", "epa dha", "vascepa", "icosapent", "krill oil", "algae oil", "rancid fish oil", "fish burp", "rancid", "triglycerides", "omega-3 index", "atrial fibrillation", "epa vs dha", "ifos", "krill" ], "feel_search": [ "fish burp", "rancid", "triglycerides", "omega-3 index", "atrial fibrillation", "epa vs dha", "ifos", "vascepa", "krill" ], "summary": "Omega-3 products supply EPA and DHA from fish, algae or krill; people seek lipid, mood or joint benefits, but formulations differ.", "search_blob": "omega-3 (epa/dha) omega-3 fish oil epa/dha icosapent ethyl talk epa dha icosapent ethyl vascepa-class epa krill oil (adjacent) algae oil omega 3 n-3 pufa omega3 omega 3 fishoil fish oil epa dha vascepa icosapent krill oil algae oil rancid fish oil fish burp rancid triglycerides omega-3 index atrial fibrillation epa vs dha ifos krill triglycerides recovery inflammation talk mood (discussed) heart-risk discussion omega-3 index rancid oil watch-for fish burp rancid triglycerides omega-3 index atrial fibrillation epa vs dha ifos vascepa krill omega-3 products supply epa and dha from fish, algae or krill; people seek lipid, mood or joint benefits, but formulations differ. often there is no immediate sensation beyond fishy burps or stomach upset. some people report a calmer mood while others notice little benefit. omega-3 (epa/dha) is an oral compound people look up for recovery. training logs credit fish oil; trials are modest and confounded by training. count epa+dha milligrams. 4 g icosapent ethyl is not a costco 180/120 softgel. performance staples (biohacking overlap) non-peptide systemic systemic oral epa/dha \u2014 triglycerides are the lab, rancid burps are the complaint. systemic whole-body circulating", "legal_class": null }, { "id": 289, "slug": "hmb", "name": "HMB", "aliases": [ "beta-hydroxy-beta-methylbutyrate", "Ca-HMB", "HMB-FA", "\u03b2-hydroxy \u03b2-methylbutyrate", "BetaTOR-class free acid", "hydroxymethylbutyrate", "leucine metabolite HMB" ], "type": "Non-peptide", "category": "Performance staples (biohacking overlap)", "goals_use_cases": [ "muscle spare / anti-catabolic talk", "GLP-adjacent lean-mass talk", "recovery", "sarcopenia-adjacent", "not a myostatin antibody" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "hmb", "h.m.b", "beta hydroxy beta methylbutyrate", "hydroxymethylbutyrate", "ca-hmb", "hmb-fa", "leucine metabolite", "glp hmb", "muscle spare", "glp muscle", "anti catabolic", "creatine hmb", "not bimagrumab", "cut", "sarcopenia" ], "feel_search": [ "muscle spare", "glp muscle", "anti catabolic", "creatine hmb", "not bimagrumab", "cut", "sarcopenia", "hmb-fa" ], "summary": "HMB is a metabolite of the amino acid leucine, sold as calcium HMB or free-acid HMB for muscle maintenance and recovery.", "search_blob": "hmb hmb beta-hydroxy-beta-methylbutyrate ca-hmb hmb-fa \u03b2-hydroxy \u03b2-methylbutyrate betator-class free acid hydroxymethylbutyrate leucine metabolite hmb hmb h.m.b beta hydroxy beta methylbutyrate hydroxymethylbutyrate ca-hmb hmb-fa leucine metabolite glp hmb muscle spare glp muscle anti catabolic creatine hmb not bimagrumab cut sarcopenia muscle spare / anti-catabolic talk glp-adjacent lean-mass talk recovery sarcopenia-adjacent not a myostatin antibody muscle spare glp muscle anti catabolic creatine hmb not bimagrumab cut sarcopenia hmb-fa hmb is a metabolite of the amino acid leucine, sold as calcium hmb or free-acid hmb for muscle maintenance and recovery. usually there is no buzz or pump. some hope to maintain strength during a cut, while many already-trained users notice little; stomach discomfort can occur. hmb is an oral leucine metabolite people look up for muscle. modest lean-mass and function signals, bigger when exercise is in the arm. 3 g/day is the paper number. creatine + protein + lifting still do the heavy lifting in those threads. performance staples (biohacking overlap) non-peptide systemic systemic oral leucine metabolite \u2014 muscle-spare talk on cuts and glp threads, not a myostatin antibody. systemic whole-body circulating", "legal_class": null }, { "id": 290, "slug": "testosterone", "name": "Testosterone", "aliases": [ "TRT", "test cypionate", "testosterone cypionate", "test enanthate", "testosterone enanthate", "testosterone gel", "AndroGel-class talk", "testosterone replacement", "test E", "test C" ], "type": "Non-peptide", "category": "Hormones in performance discourse", "goals_use_cases": [ "libido", "energy", "muscle", "recovery", "mood (discussed)", "TRT" ], "delivery_methods": [ "intramuscular", "subcutaneous", "topical" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "test cyp", "test e", "trt", "testosterone cyp", "androgel", "low t", "pin", "hematocrit", "libido", "cruise" ], "feel_search": [ "low t", "trt", "pin", "hematocrit", "libido", "cruise" ], "summary": "Testosterone is an androgen hormone used in replacement therapy and bodybuilding; cypionate and enanthate are commonly discussed ester forms.", "search_blob": "testosterone testosterone trt test cypionate testosterone cypionate test enanthate testosterone enanthate testosterone gel androgel-class talk testosterone replacement test e test c test cyp test e trt testosterone cyp androgel low t pin hematocrit libido cruise libido energy muscle recovery mood (discussed) trt low t trt pin hematocrit libido cruise testosterone is an androgen hormone used in replacement therapy and bodybuilding; cypionate and enanthate are commonly discussed ester forms. trt accounts describe improved energy, motivation and sex drive, but responses vary; one commenter reported substantial hair thinning. testosterone is a non-peptide compound people look up for libido. water, sleep, and libido comments often precede scale changes. schedule iii. labs, fertility, and hct are the watch-for, not a promised recomp. hormones in performance discourse non-peptide systemic clinic trt, cash trt, and ugl \u201ctest\u201d talk all collapse into one word. cypionate and enanthate are the esters named most. [community] u.s. schedule iii iii systemic whole-body circulating", "legal_class": { "schedule": "III", "label": "U.S. Schedule III" } }, { "id": 295, "slug": "modafinil", "name": "Modafinil", "aliases": [ "Provigil", "armodafinil", "Nuvigil", "moda", "smart drug modafinil", "wakefulness agent" ], "type": "Non-peptide", "category": "Wakefulness agents in productivity discourse", "goals_use_cases": [ "focus (discussed)", "wakefulness", "productivity (discussed)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "provigil", "nuvigil", "armodafinil", "modalert", "moda", "clean stim", "forgot to eat", "insomnia", "focus", "not adderall" ], "feel_search": [ "moda", "clean stim", "forgot to eat", "insomnia", "focus", "not adderall" ], "summary": "Modafinil is a prescription wakefulness medicine; people also discuss it for staying alert through work, study or shift schedules.", "search_blob": "modafinil modafinil provigil armodafinil nuvigil moda smart drug modafinil wakefulness agent provigil nuvigil armodafinil modalert moda clean stim forgot to eat insomnia focus not adderall focus (discussed) wakefulness productivity (discussed) moda clean stim forgot to eat insomnia focus not adderall modafinil is a prescription wakefulness medicine; people also discuss it for staying alert through work, study or shift schedules. some describe steady alertness or easier sustained attention; others feel little. appetite loss and difficulty sleeping can outlast the useful work period. modafinil is an oral wakefulness tablet people look up for focus. some feel a quiet on-switch; some feel nothing. schedule iv. late doses and sharing a plan that lists it are the watch-for. wakefulness agents in productivity discourse non-peptide systemic provigil / generic modafinil 100\u2013200 mg as a workday \u201cclean stimulant,\u201d plus armodafinil (nuvigil) as the longer sibling. [community] u.s. schedule iv iv systemic whole-body circulating", "legal_class": { "schedule": "IV", "label": "U.S. Schedule IV" } }, { "id": 296, "slug": "nicotine-pouches", "name": "Nicotine pouches", "aliases": [ "Zyn", "nicotine pouch", "oral nicotine", "nicotine gum (adjacent)", "On! pouches", "Velo pouches" ], "type": "Non-peptide", "category": "Stimulants in focus discourse", "goals_use_cases": [ "focus (discussed)", "appetite (discussed)", "alertness" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "zyn", "nicotine pouch", "velo", "on pouches", "nic pouches", "pouch", "buzz", "appetite", "addiction", "focus" ], "feel_search": [ "zyn", "pouch", "buzz", "appetite", "addiction", "focus" ], "summary": "Nicotine pouches release nicotine through the mouth; people use them for a short buzz or focus, and repeated use can lead to dependence.", "search_blob": "nicotine pouches nicotine-pouches zyn nicotine pouch oral nicotine nicotine gum (adjacent) on! pouches velo pouches zyn nicotine pouch velo on pouches nic pouches pouch buzz appetite addiction focus focus (discussed) appetite (discussed) alertness zyn pouch buzz appetite addiction focus nicotine pouches release nicotine through the mouth; people use them for a short buzz or focus, and repeated use can lead to dependence. people describe a brief buzz, focus or mental relief, but nausea and irritation can occur. with repeated use, the noticeable relief may coexist with cravings or irritability between pouches. nicotine pouches are an oral product people look up for focus. buzz, then a plateau. not a us schedule listing. still nicotine. sharing a plan that lists it can make that visible. stimulants in focus discourse non-peptide systemic zyn-style oral pouches as a nootropic/focus tool, not a smoking-cessation lecture. [community] age-restricted / locally regulated listed systemic whole-body circulating", "legal_class": { "schedule": "listed", "label": "Age-restricted / locally regulated" } }, { "id": 298, "slug": "mesterolone", "name": "Mesterolone", "aliases": [ "Proviron", "Provironum", "Androviron", "1-methyl-DHT", "1\u03b1-methyl DHT", "oral DHT derivative" ], "type": "Non-peptide", "category": "Hormones in performance discourse", "goals_use_cases": [ "libido", "mood (discussed)", "SHBG (discussed)", "hardening (discussed)", "TRT adjunct (discussed)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "proviron", "provironum", "mesterolon", "masterolone", "1-methyl dht", "shbg", "dry", "libido", "hardening", "dht" ], "feel_search": [ "proviron", "shbg", "dry", "libido", "hardening", "dht" ], "summary": "Mesterolone (Proviron) is an oral DHT-derived androgen, discussed as a TRT or steroid-cycle add-on for libido, mood and a drier appearance.", "search_blob": "mesterolone mesterolone proviron provironum androviron 1-methyl-dht 1\u03b1-methyl dht oral dht derivative proviron provironum mesterolon masterolone 1-methyl dht shbg dry libido hardening dht libido mood (discussed) shbg (discussed) hardening (discussed) trt adjunct (discussed) proviron shbg dry libido hardening dht mesterolone (proviron) is an oral dht-derived androgen, discussed as a trt or steroid-cycle add-on for libido, mood and a drier appearance. mesterolone is an oral compound people look up for libido. mood and libido comments show up before body-composition talk. schedule iii. hair, prostate, counterfeits, and sharing a plan that lists it are the watch-for. hormones in performance discourse non-peptide systemic bayer/schering proviron tablets \u2014 an oral dht-shaped androgen used as a trt add-on, not as a mass-builder. [community] u.s. schedule iii iii systemic whole-body circulating", "legal_class": { "schedule": "III", "label": "U.S. Schedule III" } }, { "id": 300, "slug": "trenbolone", "name": "Trenbolone", "aliases": [ "tren", "tren ace", "trenbolone acetate", "tren enanthate", "tren e", "Parabolan-class talk" ], "type": "Non-peptide", "category": "Hormones in performance discourse", "goals_use_cases": [ "muscle growth", "hardening (discussed)", "fat loss (discussed)", "strength", "night sweats (watch-for)" ], "delivery_methods": [ "intramuscular", "subcutaneous" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "tren a", "tren e", "parabolan", "trenbolone ace", "tren", "night sweats", "tren cough", "insomnia", "blast" ], "feel_search": [ "tren", "night sweats", "tren cough", "insomnia", "blast" ], "summary": "Trenbolone is an anabolic-androgenic steroid discussed in bodybuilding, usually as acetate or enanthate esters.", "search_blob": "trenbolone trenbolone tren tren ace trenbolone acetate tren enanthate tren e parabolan-class talk tren a tren e parabolan trenbolone ace tren night sweats tren cough insomnia blast muscle growth hardening (discussed) fat loss (discussed) strength night sweats (watch-for) tren night sweats tren cough insomnia blast trenbolone is an anabolic-androgenic steroid discussed in bodybuilding, usually as acetate or enanthate esters. accounts describe strength and drive alongside sweating, disturbed sleep, anxiety and worse exercise tolerance; some reported few mental changes. trenbolone is a non-peptide compound people look up for muscle. pump, warmth, and \u201ctren cough\u201d stories on acetate. schedule iii. night sweats, sleep, prolactin talk, and blood pressure show up more than a promised recomp. hormones in performance discourse non-peptide systemic injectable 19-nor androgen in enhanced-athlete talk \u2014 acetate and enanthate, not a sarm and not testosterone. u.s. schedule iii iii systemic whole-body circulating", "legal_class": { "schedule": "III", "label": "U.S. Schedule III" } }, { "id": 301, "slug": "nandrolone", "name": "Nandrolone", "aliases": [ "Deca", "Deca-Durabolin", "nandrolone decanoate", "NPP", "nandrolone phenylpropionate", "19-nor" ], "type": "Non-peptide", "category": "Hormones in performance discourse", "goals_use_cases": [ "joint comfort (discussed)", "muscle growth", "recovery", "strength" ], "delivery_methods": [ "intramuscular" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "deca durabolin", "nandrolone deca", "phenylpropionate", "deca", "npp", "joints", "deca dick", "19-nor" ], "feel_search": [ "deca", "npp", "joints", "deca dick", "19-nor" ], "summary": "Nandrolone is an anabolic steroid used as Deca or NPP injections; people discuss muscle gain and joint comfort, with different ester durations.", "search_blob": "nandrolone nandrolone deca deca-durabolin nandrolone decanoate npp nandrolone phenylpropionate 19-nor deca durabolin nandrolone deca phenylpropionate deca npp joints deca dick 19-nor joint comfort (discussed) muscle growth recovery strength deca npp joints deca dick 19-nor nandrolone is an anabolic steroid used as deca or npp injections; people discuss muscle gain and joint comfort, with different ester durations. users describe fuller muscles, strength or easier joints, but libido, mood and water retention vary. some report intrusive rumination or anxiety that makes the tradeoff unacceptable. nandrolone is a non-peptide compound people look up for muscle. full, smooth look is common; some call it quality mass, some call it bloat. schedule iii. water, prolactin, and libido crash stories sit next to the joint praise. hormones in performance discourse non-peptide systemic injectable 19-nor \u2014 deca is the slow ester, npp the short one. not testosterone. u.s. schedule iii iii systemic whole-body circulating", "legal_class": { "schedule": "III", "label": "U.S. Schedule III" } }, { "id": 302, "slug": "oxandrolone", "name": "Oxandrolone", "aliases": [ "Anavar", "Var", "oxandrolone 10 mg", "oxandrolone 25 mg" ], "type": "Non-peptide", "category": "Hormones in performance discourse", "goals_use_cases": [ "hardening (discussed)", "strength", "fat loss (discussed)", "women\u2019s oral AAS (discussed)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "anavar 10", "oxandrin", "anavar 25", "anavar", "var", "dry", "cut", "women" ], "feel_search": [ "anavar", "var", "dry", "cut", "women" ], "summary": "Oxandrolone (Anavar) is an oral anabolic steroid discussed for strength and a leaner appearance; it is not a SARM.", "search_blob": "oxandrolone oxandrolone anavar var oxandrolone 10 mg oxandrolone 25 mg anavar 10 oxandrin anavar 25 anavar var dry cut women hardening (discussed) strength fat loss (discussed) women\u2019s oral aas (discussed) anavar var dry cut women oxandrolone (anavar) is an oral anabolic steroid discussed for strength and a leaner appearance; it is not a sarm. users describe stronger lifts and pumps, sometimes with appetite loss or painful back pumps. feeling good can coexist with unfavorable lab changes; experiences vary. oxandrolone is an oral compound people look up for fat loss. strength and pumps before the mirror changes. lipids, liver (17-aa), and women\u2019s virilization are the watch-for, not a promised tight look. hormones in performance discourse non-peptide systemic oral dht-shaped aas \u2014 anavar in cut and \u201cquality\u201d talk, including a lot of women\u2019s threads. u.s. schedule iii iii systemic whole-body circulating", "legal_class": { "schedule": "III", "label": "U.S. Schedule III" } }, { "id": 303, "slug": "stanozolol", "name": "Stanozolol", "aliases": [ "Winstrol", "Winny", "stanozolol oral", "stanozolol injectable", "Winstrol Depot-class talk" ], "type": "Non-peptide", "category": "Hormones in performance discourse", "goals_use_cases": [ "hardening (discussed)", "strength", "cut (discussed)", "vascularity (discussed)" ], "delivery_methods": [ "oral", "intramuscular" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "winstrol depot", "stanozolol winny", "winstrol", "winny", "dry joints", "vascular" ], "feel_search": [ "winstrol", "winny", "dry joints", "vascular" ], "summary": "Stanozolol, or Winstrol, is an anabolic steroid discussed for strength and a drier physique, sold in oral and injectable forms.", "search_blob": "stanozolol stanozolol winstrol winny stanozolol oral stanozolol injectable winstrol depot-class talk winstrol depot stanozolol winny winstrol winny dry joints vascular hardening (discussed) strength cut (discussed) vascularity (discussed) winstrol winny dry joints vascular stanozolol, or winstrol, is an anabolic steroid discussed for strength and a drier physique, sold in oral and injectable forms. users describe a drier, more vascular look and stronger gym drive, with sharply mixed reports of joint pain and irritability. stanozolol is an oral compound people look up for strength. dry mouth, harder pumps, sometimes joint noise. schedule iii. dry joints, lipids, and hairline are the watch-for. hormones in performance discourse non-peptide systemic oral or injectable dht-shaped aas \u2014 winstrol in pre-contest dry talk. u.s. schedule iii iii systemic whole-body circulating", "legal_class": { "schedule": "III", "label": "U.S. Schedule III" } }, { "id": 304, "slug": "boldenone", "name": "Boldenone", "aliases": [ "Equipoise", "EQ", "boldenone undecylenate", "bold" ], "type": "Non-peptide", "category": "Hormones in performance discourse", "goals_use_cases": [ "appetite (discussed)", "endurance (discussed)", "muscle growth", "red blood cells (watch-for)" ], "delivery_methods": [ "intramuscular" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "boldenone eq", "equipoise 300", "equipoise", "eq", "appetite", "hematocrit" ], "feel_search": [ "equipoise", "eq", "appetite", "hematocrit" ], "summary": "Boldenone undecylenate (Equipoise/EQ) is a long-acting injectable anabolic steroid of veterinary origin, discussed for appetite and muscle gain.", "search_blob": "boldenone boldenone equipoise eq boldenone undecylenate bold boldenone eq equipoise 300 equipoise eq appetite hematocrit appetite (discussed) endurance (discussed) muscle growth red blood cells (watch-for) equipoise eq appetite hematocrit boldenone undecylenate (equipoise/eq) is a long-acting injectable anabolic steroid of veterinary origin, discussed for appetite and muscle gain. a forum user describes intense hunger alongside apathy, depressed mood and daytime sleepiness. testosterone co-use and self-interpreted estradiol changes complicate the account. boldenone is an injectable steroid people look up for appetite and muscle. appetite / food is the unexpected hook in a lot of logs. schedule iii. hematocrit and the long ester tail are the watch-for. hormones in performance discourse non-peptide systemic long-ester injectable \u2014 equipoise in slow-bulk and \u201ccardio on cycle\u201d talk. u.s. schedule iii iii systemic whole-body circulating", "legal_class": { "schedule": "III", "label": "U.S. Schedule III" } }, { "id": 305, "slug": "drostanolone", "name": "Drostanolone", "aliases": [ "Masteron", "Mast", "drostanolone enanthate", "drostanolone propionate", "Masteron prop" ], "type": "Non-peptide", "category": "Hormones in performance discourse", "goals_use_cases": [ "muscle", "hardening (discussed)", "dry look (discussed)", "DHT sides (watch-for)" ], "delivery_methods": [ "intramuscular" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "masteron enanthate", "masteron prop", "drostanolone mast", "masteron", "mast", "dry", "hard" ], "feel_search": [ "masteron", "mast", "dry", "hard" ], "summary": "Drostanolone (Masteron) is an injectable anabolic steroid sold in propionate or enanthate forms, discussed for strength and a harder physique.", "search_blob": "drostanolone drostanolone masteron mast drostanolone enanthate drostanolone propionate masteron prop masteron enanthate masteron prop drostanolone mast masteron mast dry hard muscle hardening (discussed) dry look (discussed) dht sides (watch-for) masteron mast dry hard drostanolone (masteron) is an injectable anabolic steroid sold in propionate or enanthate forms, discussed for strength and a harder physique. one user describes strength and mood benefits with a flatter look; a long-term user describes a leaner look but severe later hair loss. these are individual accounts. drostanolone is a non-peptide compound people look up for muscle. first weeks: skin/hardness comments before scale changes. schedule iii. hairline, prostate talk, and a look that vanishes without the diet. hormones in performance discourse non-peptide systemic injectable dht-shaped aas \u2014 masteron in late-cut hardness talk. u.s. schedule iii iii systemic whole-body circulating", "legal_class": { "schedule": "III", "label": "U.S. Schedule III" } }, { "id": 306, "slug": "methenolone", "name": "Methenolone", "aliases": [ "Primobolan", "Primo", "Primobolan Depot", "methenolone enanthate", "methenolone acetate" ], "type": "Non-peptide", "category": "Hormones in performance discourse", "goals_use_cases": [ "muscle", "quality mass (discussed)", "hardening (discussed)", "expensive mild AAS (discussed)" ], "delivery_methods": [ "intramuscular", "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "primobolan depot", "methenolone primo", "primo", "primobolan", "quality", "fake primo" ], "feel_search": [ "primo", "primobolan", "quality", "fake primo" ], "summary": "Methenolone (Primobolan) is an anabolic steroid available as injectable enanthate or oral acetate, discussed for gradual physique and strength changes.", "search_blob": "methenolone methenolone primobolan primo primobolan depot methenolone enanthate methenolone acetate primobolan depot methenolone primo primo primobolan quality fake primo muscle quality mass (discussed) hardening (discussed) expensive mild aas (discussed) primo primobolan quality fake primo methenolone (primobolan) is an anabolic steroid available as injectable enanthate or oral acetate, discussed for gradual physique and strength changes. changes may be subtle: some describe a harder appearance or better training, while others are unsure. the mixed-cycle account also reports injection pain; sensations do not verify product identity. methenolone is an oral compound people look up for muscle. slight hardness/size; or \u201ci got scammed.\u201d schedule iii. fake primo and hairline are the watch-for. hormones in performance discourse non-peptide systemic mild dht-shaped aas \u2014 primobolan depot in \u201cquality, expensive, maybe fake\u201d talk. u.s. schedule iii iii systemic whole-body circulating", "legal_class": { "schedule": "III", "label": "U.S. Schedule III" } }, { "id": 307, "slug": "methandrostenolone", "name": "Methandrostenolone", "aliases": [ "Dianabol", "Dbol", "methandienone", "Dianabol 10 mg" ], "type": "Non-peptide", "category": "Hormones in performance discourse", "goals_use_cases": [ "rapid size (discussed)", "strength", "pumps (discussed)", "water (watch-for)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "dianabol 10", "methandienone", "dbol 30", "dbol", "dianabol", "pumps", "water weight" ], "feel_search": [ "dbol", "dianabol", "pumps", "water weight" ], "summary": "Methandrostenolone (Dianabol or Dbol) is an oral anabolic steroid, discussed for rapid strength, pumps and scale-weight gain that includes water.", "search_blob": "methandrostenolone methandrostenolone dianabol dbol methandienone dianabol 10 mg dianabol 10 methandienone dbol 30 dbol dianabol pumps water weight rapid size (discussed) strength pumps (discussed) water (watch-for) dbol dianabol pumps water weight methandrostenolone (dianabol or dbol) is an oral anabolic steroid, discussed for rapid strength, pumps and scale-weight gain that includes water. methandrostenolone is an oral compound people look up for strength. appetite, pumps, scale jump. schedule iii. liver, gyno, bp, and the bounce-back after you stop. hormones in performance discourse non-peptide systemic classic oral aas \u2014 dianabol in \u201cfirst cycle\u201d size-and-water talk. u.s. schedule iii iii systemic whole-body circulating", "legal_class": { "schedule": "III", "label": "U.S. Schedule III" } }, { "id": 308, "slug": "oxymetholone", "name": "Oxymetholone", "aliases": [ "Anadrol", "Adrol", "Anadrol 50", "oxymetholone 50 mg" ], "type": "Non-peptide", "category": "Hormones in performance discourse", "goals_use_cases": [ "rapid size (discussed)", "appetite (discussed)", "strength", "water (watch-for)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "anadrol 50", "oxymetholone 50", "anadrol", "adrol", "appetite", "water" ], "feel_search": [ "anadrol", "adrol", "appetite", "water" ], "summary": "Oxymetholone (Anadrol) is an oral anabolic steroid discussed for rapid strength and size changes, with variable water and appetite effects.", "search_blob": "oxymetholone oxymetholone anadrol adrol anadrol 50 oxymetholone 50 mg anadrol 50 oxymetholone 50 anadrol adrol appetite water rapid size (discussed) appetite (discussed) strength water (watch-for) anadrol adrol appetite water oxymetholone (anadrol) is an oral anabolic steroid discussed for rapid strength and size changes, with variable water and appetite effects. some feel stronger and fuller quickly; others get headache, nausea, heartburn or poor appetite. a rapid scale change includes water and is not a direct measure of new muscle. oxymetholone is an oral compound people look up for appetite. scale and strength in days for some logs. schedule iii. liver, bp, prolactin-ish sides, and \u201cnever again\u201d posts. hormones in performance discourse non-peptide systemic heavy oral aas \u2014 anadrol 50 in \u201cnuclear appetite and water\u201d talk. u.s. schedule iii iii systemic whole-body circulating", "legal_class": { "schedule": "III", "label": "U.S. Schedule III" } }, { "id": 309, "slug": "turinabol", "name": "Turinabol", "aliases": [ "Tbol", "chlorodehydromethyltestosterone", "4-chlorodehydromethyltestosterone", "Turinabol 10 mg" ], "type": "Non-peptide", "category": "Hormones in performance discourse", "goals_use_cases": [ "dryer oral size (discussed)", "strength", "slower than Dbol (discussed)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "tbol 10", "chlorodehydromethyltestosterone", "tbol", "turinabol", "dry dbol" ], "feel_search": [ "tbol", "turinabol", "dry dbol" ], "summary": "Turinabol, or Tbol, is chlorodehydromethyltestosterone, an oral anabolic steroid discussed for strength and muscle.", "search_blob": "turinabol turinabol tbol chlorodehydromethyltestosterone 4-chlorodehydromethyltestosterone turinabol 10 mg tbol 10 chlorodehydromethyltestosterone tbol turinabol dry dbol dryer oral size (discussed) strength slower than dbol (discussed) tbol turinabol dry dbol turinabol, or tbol, is chlorodehydromethyltestosterone, an oral anabolic steroid discussed for strength and muscle. some users describe stronger pumps and a drier look; others stopped because of headaches, and one reported lethargy at higher exposure. turinabol is an oral compound people look up for strength. strength with less water than dbol is the pitch. schedule iii. still a 17-aa liver oral. slower screenshots than dbol. hormones in performance discourse non-peptide systemic oral aas \u2014 turinabol as \u201cdbol\u2019s drier, slower cousin\u201d in forum talk. u.s. schedule iii iii systemic whole-body circulating", "legal_class": { "schedule": "III", "label": "U.S. Schedule III" } }, { "id": 310, "slug": "clenbuterol", "name": "Clenbuterol", "aliases": [ "Clen", "clenbuterol 40 mcg", "clen tabs" ], "type": "Non-peptide", "category": "Mitochondrial & metabolic compounds", "goals_use_cases": [ "fat loss (discussed)", "tremor (watch-for)", "heart rate (watch-for)", "cramps (watch-for)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "clenbuterol 40", "clen 40mcg", "clen", "shakes", "cramps", "heart rate", "cut" ], "feel_search": [ "clen", "shakes", "cramps", "heart rate", "cut" ], "summary": "Clenbuterol is a beta-2 agonist bronchodilator discussed off-label for fat loss; it is not an anabolic steroid.", "search_blob": "clenbuterol clenbuterol clen clenbuterol 40 mcg clen tabs clenbuterol 40 clen 40mcg clen shakes cramps heart rate cut fat loss (discussed) tremor (watch-for) heart rate (watch-for) cramps (watch-for) clen shakes cramps heart rate cut clenbuterol is a beta-2 agonist bronchodilator discussed off-label for fat loss; it is not an anabolic steroid. reports range from gym energy with little noticed trouble to shaking, a racing heart and insomnia lasting into the night. co-stimulants and product identity vary. clenbuterol is an oral compound people look up for fat loss. heat / fidget / appetite down in some logs. not a csa anabolic. still a heart-rate drug in those logs. taurine/cramp folklore is not a protocol. mitochondrial & metabolic compounds non-peptide systemic oral beta-2 agonist in cut talk \u2014 not a steroid and not a sarm. systemic whole-body circulating", "legal_class": null }, { "id": 311, "slug": "tamoxifen", "name": "Tamoxifen", "aliases": [ "Nolvadex", "Nolva", "tamoxifen citrate", "tamoxifen 20 mg" ], "type": "Non-peptide", "category": "Hormone modulators", "goals_use_cases": [ "PCT (discussed)", "gyno scare (discussed)", "SERM (not an AI)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "nolvadex 20", "tamoxifen pct", "nolvadex", "nolva", "pct", "gyno" ], "feel_search": [ "nolvadex", "nolva", "pct", "gyno" ], "summary": "Tamoxifen (Nolvadex) is an oral selective estrogen-receptor modulator, or SERM, also discussed for gynecomastia and post-cycle hormone concerns.", "search_blob": "tamoxifen tamoxifen nolvadex nolva tamoxifen citrate tamoxifen 20 mg nolvadex 20 tamoxifen pct nolvadex nolva pct gyno pct (discussed) gyno scare (discussed) serm (not an ai) nolvadex nolva pct gyno tamoxifen (nolvadex) is an oral selective estrogen-receptor modulator, or serm, also discussed for gynecomastia and post-cycle hormone concerns. one user described a smaller breast lump but severe low mood, fatigue and poor concentration after switching medicines. tamoxifen is an oral tablet people look up for gyno during pct. pct testosterone recovery folklore with clomid or instead of it. not a csa steroid. clot/mood/vision stories exist. not aromasin and not clomid. hormone modulators non-peptide systemic oral serm \u2014 nolvadex in pct and gyno-scare talk, not an aromatase inhibitor. systemic whole-body circulating", "legal_class": null }, { "id": 312, "slug": "exemestane", "name": "Exemestane", "aliases": [ "Aromasin", "Asin", "exemestane 25 mg", "suicidal AI" ], "type": "Non-peptide", "category": "Hormone modulators", "goals_use_cases": [ "estradiol control on TRT / AAS (discussed)", "suicidal AI (discussed)", "less crash than Adex (argued)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "High", "reach": "Systemic", "misspellings_search_terms": [ "aromasin 25", "exemestane 12.5", "aromasin", "asin", "ai crash", "estradiol" ], "feel_search": [ "aromasin", "asin", "ai crash", "estradiol" ], "summary": "Exemestane (Aromasin) is an oral steroidal aromatase inhibitor that irreversibly reduces aromatase activity and lowers new estrogen production.", "search_blob": "exemestane exemestane aromasin asin exemestane 25 mg suicidal ai aromasin 25 exemestane 12.5 aromasin asin ai crash estradiol estradiol control on trt / aas (discussed) suicidal ai (discussed) less crash than adex (argued) aromasin asin ai crash estradiol exemestane (aromasin) is an oral steroidal aromatase inhibitor that irreversibly reduces aromatase activity and lowers new estrogen production. a trt-related account reports very low measured estradiol, stiff painful joints, sexual symptoms and slow improvement. other treatment changes make a recovery clock uncertain. exemestane is an oral compound people look up for estradiol. low-e2 (dry joints, flat libido) if the dose is too much. not a csa steroid. joint dryness and a crashed libido still happen. not nolvadex. hormone modulators non-peptide systemic oral suicidal aromatase inhibitor \u2014 aromasin in \u201cadex crashed me\u201d threads. systemic whole-body circulating", "legal_class": null }, { "id": 313, "slug": "liothyronine", "name": "Liothyronine", "aliases": [ "T3", "Cytomel-class talk", "liothyronine 25 mcg", "triiodothyronine" ], "type": "Non-peptide", "category": "Mitochondrial & metabolic compounds", "goals_use_cases": [ "heart", "contest prep (discussed)", "metabolic rate (discussed)", "catabolism (watch-for)", "heart rate (watch-for)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "t3 25mcg", "liothyronine cytomel", "t3", "cytomel", "thyroid cut", "hot" ], "feel_search": [ "t3", "cytomel", "thyroid cut", "hot" ], "summary": "Liothyronine is synthetic T3 thyroid hormone, sold as Cytomel. People discuss it for thyroid replacement and, separately, bodybuilding cuts.", "search_blob": "liothyronine liothyronine t3 cytomel-class talk liothyronine 25 mcg triiodothyronine t3 25mcg liothyronine cytomel t3 cytomel thyroid cut hot heart contest prep (discussed) metabolic rate (discussed) catabolism (watch-for) heart rate (watch-for) t3 cytomel thyroid cut hot liothyronine is synthetic t3 thyroid hormone, sold as cytomel. people discuss it for thyroid replacement and, separately, bodybuilding cuts. some accounts describe more alertness or energy; others describe no benefit, an afternoon crash, anxiety or sleep disruption. liothyronine is an oral compound people look up for thyroid. warmth, pulse, sometimes anxiety. not csa. tsh suppression and rebound talk. not a fat-burner to leave on. mitochondrial & metabolic compounds non-peptide systemic oral t3 thyroid hormone in contest-prep talk \u2014 not clen, not a steroid. systemic whole-body circulating", "legal_class": null }, { "id": 314, "slug": "dihydroboldenone", "name": "Dihydroboldenone", "aliases": [ "DHB", "1-testosterone", "1-test", "delta-1 DHT", "dihydroboldenone cypionate", "1-testosterone cypionate" ], "type": "Non-peptide", "category": "Hormones in performance discourse", "goals_use_cases": [ "hardening (discussed)", "strength", "EQ-adjacent (discussed)", "injection pain (watch-for)" ], "delivery_methods": [ "intramuscular" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "dihydroboldenone", "1 testosterone", "dhb cyp", "dhb", "1-test", "pip", "equipoise cousin" ], "feel_search": [ "dhb", "1-test", "pip", "equipoise cousin" ], "summary": "Dihydroboldenone (DHB/1-testosterone) is an anabolic steroid discussed as an injection for strength and physique goals; it is distinct from Equipoise.", "search_blob": "dihydroboldenone dihydroboldenone dhb 1-testosterone 1-test delta-1 dht dihydroboldenone cypionate 1-testosterone cypionate dihydroboldenone 1 testosterone dhb cyp dhb 1-test pip equipoise cousin hardening (discussed) strength eq-adjacent (discussed) injection pain (watch-for) dhb 1-test pip equipoise cousin dihydroboldenone (dhb/1-testosterone) is an anabolic steroid discussed as an injection for strength and physique goals; it is distinct from equipoise. stacked-use accounts describe fullness and strength alongside irritability or painful injections. users disagree about how much formulation and individual response explain the pain. dihydroboldenone is a non-peptide compound people look up for strength. hard / quality look in some cut logs next to eq. schedule iii as 1-testosterone. boards still argue whether most dhb is real. hormones in performance discourse non-peptide systemic injectable 1-testosterone / dhb in aas talk \u2014 next to eq, not testosterone cypionate. u.s. schedule iii iii systemic whole-body circulating", "legal_class": { "schedule": "III", "label": "U.S. Schedule III" } }, { "id": 315, "slug": "trestolone", "name": "Trestolone", "aliases": [ "MENT", "trest", "trestolone acetate", "7\u03b1-methyl-19-nortestosterone", "MENT acetate" ], "type": "Non-peptide", "category": "Hormones in performance discourse", "goals_use_cases": [ "suppression (discussed)", "estrogen from 19-nor (discussed)", "strength", "libido (split)" ], "delivery_methods": [ "intramuscular" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "trestolone acetate", "ment acetate", "7a-methyl-19-nor", "ment", "trest", "suppressive", "19-nor" ], "feel_search": [ "ment", "trest", "suppressive", "19-nor" ], "summary": "Trestolone, or MENT, is 7\u03b1-methyl-19-nortestosterone, an injectable anabolic-androgenic steroid discussed for muscle and strength.", "search_blob": "trestolone trestolone ment trest trestolone acetate 7\u03b1-methyl-19-nortestosterone ment acetate trestolone acetate ment acetate 7a-methyl-19-nor ment trest suppressive 19-nor suppression (discussed) estrogen from 19-nor (discussed) strength libido (split) ment trest suppressive 19-nor trestolone, or ment, is 7\u03b1-methyl-19-nortestosterone, an injectable anabolic-androgenic steroid discussed for muscle and strength. reports range from little noticeable change to strong gym and libido effects, with nipple sensitivity, water retention or fatigue in some accounts. trestolone is an injectable steroid people look up for strength. strength / fullness in short acetate logs. not a named csa schedule iii steroid on the 86-item list. boards still treat it as a steroid. analogue rules may apply; this card is not a legal opinion. hormones in performance discourse non-peptide systemic 19-nor ment / trestolone in \u201cmost suppressive\u201d aas talk \u2014 not testosterone and not tren. systemic whole-body circulating", "legal_class": null }, { "id": 316, "slug": "methasterone", "name": "Methasterone", "aliases": [ "SuperDrol", "Superdrol", "SD", "methyldrostanolone", "methasterone oral" ], "type": "Non-peptide", "category": "Hormones in performance discourse", "goals_use_cases": [ "rapid strength (discussed)", "dry oral (discussed)", "liver (watch-for)", "short run (discussed)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "superdrol 10", "methyldrostanolone", "methasterone", "superdrol", "sdrol", "back pumps", "liver oral" ], "feel_search": [ "superdrol", "sdrol", "back pumps", "liver oral" ], "summary": "Methasterone (Superdrol) is an oral anabolic steroid, discussed for rapid strength and a dense look alongside substantial fatigue and liver-risk concerns.", "search_blob": "methasterone methasterone superdrol superdrol sd methyldrostanolone methasterone oral superdrol 10 methyldrostanolone methasterone superdrol sdrol back pumps liver oral rapid strength (discussed) dry oral (discussed) liver (watch-for) short run (discussed) superdrol sdrol back pumps liver oral methasterone (superdrol) is an oral anabolic steroid, discussed for rapid strength and a dense look alongside substantial fatigue and liver-risk concerns. methasterone is an oral compound people look up for strength. strength and back pumps. schedule iii. two-to-four-week folklore. not anavar. hormones in performance discourse non-peptide systemic 17-aa oral dht-shaped aas \u2014 superdrol in \u201ctwo-week nuclear oral\u201d talk. u.s. schedule iii iii systemic whole-body circulating", "legal_class": { "schedule": "III", "label": "U.S. Schedule III" } }, { "id": 317, "slug": "letrozole", "name": "Letrozole", "aliases": [ "Femara", "letro", "letrozole 2.5 mg", "letrozole AI" ], "type": "Non-peptide", "category": "Hormone modulators", "goals_use_cases": [ "estradiol crash (watch-for)", "gyno last-resort (discussed)", "fertility/TTC adjacency", "strong AI (discussed)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "letrozole 2.5", "femara letro", "letro", "femara", "e2 crash", "ai" ], "feel_search": [ "letro", "femara", "e2 crash", "ai" ], "summary": "Letrozole is an aromatase inhibitor that lowers estrogen production; discussions span prescribed fertility care and off-label hormone management.", "search_blob": "letrozole letrozole femara letro letrozole 2.5 mg letrozole ai letrozole 2.5 femara letro letro femara e2 crash ai estradiol crash (watch-for) gyno last-resort (discussed) fertility/ttc adjacency strong ai (discussed) letro femara e2 crash ai letrozole is an aromatase inhibitor that lowers estrogen production; discussions span prescribed fertility care and off-label hormone management. some describe joint aches, fatigue, headaches or flatter mood; others report no noticeable symptoms. experiences differ across fertility care and hormone-use discussions. letrozole is an oral aromatase inhibitor people look up for gyno. low-e2 (dry joints, flat mood) if the slice is too big. not a csa steroid. 2026 meso regulars say almost nobody uses it first-line vs adex/asin. hormone modulators non-peptide systemic oral non-steroidal ai \u2014 femara as the \u201cnuclear adex\u201d in trt/aas talk. systemic whole-body circulating", "legal_class": null }, { "id": 318, "slug": "raloxifene", "name": "Raloxifene", "aliases": [ "Evista", "ralox", "raloxifene 60 mg", "gyno SERM" ], "type": "Non-peptide", "category": "Hormone modulators", "goals_use_cases": [ "gyno (discussed)", "PCT SERM (discussed)", "vs Nolvadex (discussed)", "lipids (watch-for)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "raloxifene 60", "evista ralox", "ralox", "evista", "gyno serm", "pct" ], "feel_search": [ "ralox", "evista", "gyno serm", "pct" ], "summary": "Raloxifene (Evista) is an oral selective estrogen-receptor modulator, or SERM, discussed in bodybuilding forums for gynecomastia.", "search_blob": "raloxifene raloxifene evista ralox raloxifene 60 mg gyno serm raloxifene 60 evista ralox ralox evista gyno serm pct gyno (discussed) pct serm (discussed) vs nolvadex (discussed) lipids (watch-for) ralox evista gyno serm pct raloxifene (evista) is an oral selective estrogen-receptor modulator, or serm, discussed in bodybuilding forums for gynecomastia. one user reported no noticeable change or side effects after three months; their later switch to tamoxifen also changed another medication. raloxifene is an oral tablet people look up for gyno. pct alternative to nolva in some kits. not a csa steroid. 2026 meso still names it in pct/gyno lists next to clomid and nolvadex. hormone modulators non-peptide systemic oral serm \u2014 evista as the gyno serm people pick instead of nolvadex. systemic whole-body circulating", "legal_class": null }, { "id": 319, "slug": "levothyroxine", "name": "Levothyroxine", "aliases": [ "T4", "Synthroid-class talk", "levothyroxine 50 mcg", "L-thyroxine", "levothyroxine sodium" ], "type": "Non-peptide", "category": "Mitochondrial & metabolic compounds", "goals_use_cases": [ "thyroid replacement (discussed)", "contest T4+T3 (discussed)", "TSH (watch-for)", "slow vs T3 (discussed)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "levothyroxine 50", "synthroid t4", "l-thyroxine", "t4", "synthroid", "levothyroxine", "tsh" ], "feel_search": [ "t4", "synthroid", "levothyroxine", "tsh" ], "summary": "Levothyroxine is synthetic T4 used to replace missing thyroid hormone. The body converts T4 into T3; Synthroid is one brand.", "search_blob": "levothyroxine levothyroxine t4 synthroid-class talk levothyroxine 50 mcg l-thyroxine levothyroxine sodium levothyroxine 50 synthroid t4 l-thyroxine t4 synthroid levothyroxine tsh thyroid replacement (discussed) contest t4+t3 (discussed) tsh (watch-for) slow vs t3 (discussed) t4 synthroid levothyroxine tsh levothyroxine is synthetic t4 used to replace missing thyroid hormone. the body converts t4 into t3; synthroid is one brand. reports include steadier energy and improvement in low-thyroid symptoms, but also persistent fatigue or brain fog despite improved tests. levothyroxine is an oral compound people look up for thyroid. t4 is slow. people who expect t3 heat are disappointed. not csa. excelmale still charts t4 vs armour vs cytomel as separate identities. boxed warning against obesity use in euthyroid people. mitochondrial & metabolic compounds non-peptide systemic oral t4 thyroid hormone \u2014 synthroid-class. slower than t3. not desiccated thyroid. systemic whole-body circulating", "legal_class": null }, { "id": 320, "slug": "desiccated-thyroid", "name": "Desiccated thyroid", "aliases": [ "NDT", "Armour Thyroid", "NP Thyroid", "Nature-Throid", "WP Thyroid", "DTE", "desiccated thyroid extract", "porcine thyroid" ], "type": "Non-peptide", "category": "Mitochondrial & metabolic compounds", "goals_use_cases": [ "hypothyroid replacement (discussed)", "Armour vs Synthroid (discussed)", "T4+T3 mix (discussed)", "grain dosing (discussed)" ], "delivery_methods": [ "oral" ], "discussion_popularity": "Medium", "reach": "Systemic", "misspellings_search_terms": [ "np thyroid", "armour thyroid", "desiccated thyroid", "dte", "armour", "ndt", "desiccated", "nature-throid" ], "feel_search": [ "armour", "np thyroid", "ndt", "desiccated", "nature-throid" ], "summary": "Desiccated thyroid is dried pig thyroid in a tablet for an underactive thyroid. Armour and NP Thyroid supply both T4 and T3 hormones.", "search_blob": "desiccated thyroid desiccated-thyroid ndt armour thyroid np thyroid nature-throid wp thyroid dte desiccated thyroid extract porcine thyroid np thyroid armour thyroid desiccated thyroid dte armour ndt desiccated nature-throid hypothyroid replacement (discussed) armour vs synthroid (discussed) t4+t3 mix (discussed) grain dosing (discussed) armour np thyroid ndt desiccated nature-throid desiccated thyroid is dried pig thyroid in a tablet for an underactive thyroid. armour and np thyroid supply both t4 and t3 hormones. some switch reports describe better energy; others describe no improvement, palpitations, tremor or disrupted sleep. the pig-thyroid tablet people switch to when synthroid \u201cfelt like nothing\u201d \u2014 np thyroid and armour are the names. felt energy vs levo in switch logs. not csa. excelmale 2026 still charts armour vs levo vs cytomel. access/fda dte talk is the clinic fight. mitochondrial & metabolic compounds non-peptide systemic porcine desiccated thyroid \u2014 armour / np thyroid / nature-throid. t4+t3 in one grain, not pure t4. systemic whole-body circulating", "legal_class": null }, { "id": 321, "slug": "abs-201", "name": "ABS-201", "aliases": [ "ABS201", "ABS 201", "prolactin receptor antagonist hair", "Absci ABS-201" ], "type": "Non-peptide", "category": "Skin, hair & tissue remodeling", "goals_use_cases": [ "androgenetic alopecia (discussed)", "prolactin-receptor hair (discussed)", "vs HMI-115 (discussed)" ], "delivery_methods": [ "intramuscular" ], "discussion_popularity": "Emerging", "reach": "Local", "misspellings_search_terms": [ "abs201", "abs 201", "prolactin receptor antibody", "abs-201", "prolactin hair", "hmi-115" ], "feel_search": [ "abs-201", "prolactin hair", "hmi-115" ], "summary": "ABS-201 is an investigational prolactin-receptor antibody being developed for hair loss.", "search_blob": "abs-201 abs-201 abs201 abs 201 prolactin receptor antagonist hair absci abs-201 abs201 abs 201 prolactin receptor antibody abs-201 prolactin hair hmi-115 androgenetic alopecia (discussed) prolactin-receptor hair (discussed) vs hmi-115 (discussed) abs-201 prolactin hair hmi-115 abs-201 is an investigational prolactin-receptor antibody being developed for hair loss. the inspected discussion covers trial announcements and injection convenience. it provides no firsthand hair-regrowth or day-to-day feel report. abs-201 is an investigational antibody people look up for hair. anyone claiming a gray-market abs-201 log is outside the named trial story. not a peptide gray-vial. not csa. amounts are trial talk, not a protocol. skin, hair & tissue remodeling non-peptide local investigational prolactin-receptor antibody in 2026 tressless/x hair talk \u2014 not minoxidil, not fin. local site pin topical", "legal_class": null }, { "id": 322, "slug": "hmi-115", "name": "HMI-115", "aliases": [ "HMI115", "HMI 115", "Hope Medicine HMI-115", "prolactin receptor antibody hair" ], "type": "Non-peptide", "category": "Skin, hair & tissue remodeling", "goals_use_cases": [ "androgenetic alopecia (discussed)", "endometriosis pipeline (adjacent)", "vs ABS-201 (discussed)" ], "delivery_methods": [ "intramuscular" ], "discussion_popularity": "Emerging", "reach": "Local", "misspellings_search_terms": [ "hmi115", "hmi 115", "hope medicine hair", "hmi-115", "prolactin antibody", "abs-201" ], "feel_search": [ "hmi-115", "prolactin antibody", "abs-201" ], "summary": "HMI-115 is an investigational antibody that blocks the prolactin receptor, being studied for pattern hair loss and endometriosis.", "search_blob": "hmi-115 hmi-115 hmi115 hmi 115 hope medicine hmi-115 prolactin receptor antibody hair hmi115 hmi 115 hope medicine hair hmi-115 prolactin antibody abs-201 androgenetic alopecia (discussed) endometriosis pipeline (adjacent) vs abs-201 (discussed) hmi-115 prolactin antibody abs-201 hmi-115 is an investigational antibody that blocks the prolactin receptor, being studied for pattern hair loss and endometriosis. the reviewed sources do not establish a typical subjective effect. hair counts and trial progress do not tell a user what an injection should feel like. hmi-115 is an investigational antibody people look up for skin. hair-loss and other prolactin-axis trial talk. not csa. not a peptide gray vial. 2026 tressless names it with abs-201. skin, hair & tissue remodeling non-peptide local investigational prolactin-receptor antibody \u2014 hmi-115 in 2026 hair-biohack talk. local site pin topical", "legal_class": null } ], "filters": { "categories": [ "Antioxidant & detox discussion", "Antioxidant & metabolic adjacents", "Antioxidant & performance adjacents", "Cognitive / nootropic peptides", "Cognitive research compounds", "Experimental oncology-adjacent peptides", "Growth factors", "Growth factors / muscle", "Growth hormone axis", "Gut & inflammation peptides", "Healing & repair", "Healing stacks (named blends)", "Herbals in hormone discourse", "Hormone modulators", "Hormones in performance discourse", "Immune & inflammation adjacents", "Immune & neuropeptides", "Immune / antimicrobial", "Immune peptides", "Libido & melanocortin", "Longevity & bioregulators", "Longevity & cellular energy", "Longevity & mTOR", "Longevity & performance staples", "Metabolic & longevity adjacents", "Metabolic / GLP-1 class", "Metabolic / fat-loss peptides", "Metabolic / melanocortin", "Metabolic hormones", "Metabolic research compounds", "Minerals in hormone discourse", "Mitochondrial & metabolic compounds", "Mitochondrial & metabolic peptides", "Neuropeptides", "Organ bioregulators", "Performance / endurance", "Performance staples (biohacking overlap)", "Reproductive & endocrine peptides", "SARMs (adjacent discourse)", "Senolytic & longevity compounds", "Senolytic research peptides", "Sexual / reproductive", "Skin, hair & tissue remodeling", "Sleep & longevity staples", "Sleep / mood", "Stimulants in focus discourse", "Tanning & melanocortin", "Wakefulness agents in productivity discourse" ], "goals_use_cases": [ "AMPK", "AMPK / nutrient-sensing interest", "AMPK pathway research tool", "Armour vs Synthroid (discussed)", "BDNF / TrkB narratives", "BPH", "BPH-adjacent community stacks", "C60-in-olive-oil biohack", "COURAGE triplet", "CR-mimetic framing", "DHT sides (watch-for)", "DIY ethanol/PG mix", "DIY multi-peptide serum building", "DIY serum booster culture", "DIY topical hair-serum culture", "DSIP comparison", "Dihexa stack (BioMind-class)", "EQ-adjacent (discussed)", "ER-stress / mitochondria halo", "GH pulse amplitude (acute)", "GI lining support (discussed)", "GLP muscle-spare talk", "GLP-1 combination interest (CagriSema)", "GLP-1 compounding add-on", "GLP-1 pipeline talk", "GLP-1 stack adjunct (community)", "GLP-1 stack talk", "GLP-adjacent lean-mass talk", "HIV lipodystrophy context", "HPG axis research", "HPTA support (discussed)", "Huberman-class bone-peptide search", "Huberman-style nightly sleep cocktail", "IGF-1 elevation (discussed)", "IGF-1 elevation support (discussed)", "IGF-1 support (discussed)", "IV med-spa wellness menus", "K-beauty \u201csalmon DNA\u201d facial", "Long COVID discussion", "MC4R pathway research", "ME/CFS discussion", "NAC stack companion", "NAD discussion", "NAFLD / liver-fat curiosity", "NGF / nerve-growth talk", "NMN / NR partner", "NMN/NR stack companion", "NNMT discussion", "NSAID-related gut complaint talk", "NSAID-related gut irritation talk", "PCOS / cycle-regularity talk", "PCOS / insulin-resistance narratives", "PCOS-adjacent community", "PCT (discussed)", "PCT / post-cycle talk", "PCT SERM (discussed)", "PCT discussion", "PPAR-\u03b3 / metabolic halo", "PWS anxiousness (investigational)", "PWS hyperphagia (investigational)", "Parkinson pipeline talk", "Parkinson-adjacent lore", "RU-58841 comparison", "SERM (not an AI)", "SHBG (discussed)", "SHBG modulation (discussed)", "SIBO / bloating experiments", "T-cell balance (discussed)", "T4+T3 mix (discussed)", "TBI recovery discussion", "TREK-1 (KCNK2) mechanism curiosity", "TRT", "TRT / high-E2 folklore", "TRT adjunct (discussed)", "TRT adjunct axis talk", "TRT alternative (discussed)", "TRT fertility preservation", "TRT-adjacent sexual function", "TSH (watch-for)", "Tren cardio offset (discussed)", "access / specialty-drug logistics", "acne (labeled 1% cream)", "activin A blockade", "add-on to minoxidil", "aesthetic remodeling", "aesthetic skin tone", "age-related GH decline discussion", "age-related cognitive interest", "age-related hepatic decline (discussed)", "age-related low-T talk (community)", "age-related metabolic decline", "aging", "aging cardiovascular support narratives", "aging male wellness (discussed)", "aging-brain repair narrative", "aging-brain support narratives", "alertness", "androgen-receptor block (discussed)", "androgenetic alopecia", "androgenetic alopecia (discussed)", "androgenetic alopecia add-on", "angiogenesis support narratives", "anti fibrotic", "anti-aging (discussed)", "anti-aging / collagen talk", "anti-aging / wellness-clinic discussion", "anti-aging discussion", "anti-apoptotic cell-stress resilience", "anti-biofilm (preclinical)", "anti-catabolism (discussed)", "anti-fibrotic interest (discussed)", "anti-inflammaging narratives", "anti-inflammatory NAD-metabolome framing", "antimicrobial discussion", "antioxidant / DNA-damage narratives", "antioxidant / redox-cycling discussion", "antioxidant discussion", "antioxidant support (discussed)", "anxiety", "anxiety / calm (discussed)", "anxiety discussion", "anxiety-adjacent talk", "apigenin stack", "appetite", "appetite (discussed)", "appetite / hard-gainer bulk", "appetite control", "appetite control (GLP-1 arm)", "appetite control / food-noise reduction", "appetite regulation via MC4R", "appetite stimulation", "appetite suppression", "appetite suppression (discussed)", "approved peptide medicine", "attention", "autoimmune discussion", "autophagy / CR-mimetic framing", "autophagy discussion", "beard fill-in (topical community)", "between-Botox maintenance talk", "biased-agonist folklore", "bladder GAG-layer lore", "blood flow", "blood pressure experiments", "blood-pressure / potassium caution", "blood-pressure support (discussed)", "body composition", "body composition (discussed)", "body composition / recomp", "body recomposition", "body recomposition (discussed)", "bone / calcium-balance talk", "bone density", "bone discussion", "bone health", "bone metabolism interest (preclinical)", "bone support (discussed)", "bone support (preclinical interest)", "brain fog (anecdotal)", "brain mito quality", "breathing-comfort narratives", "bronchiectasis mucus-clearance talk", "bulking (community framing)", "caffeine stack", "cagrilintide / CagriSema comparison", "cagrilintide / eloralintide comparison", "calm focus", "cancer-risk observational interest", "cardiac/organ repair narratives", "cardio capacity (discussed)", "cardiometabolic risk discussion", "cardiometabolic risk markers (discussed)", "cardiometabolic risk talk", "cardiovascular", "cardiovascular / heart-tissue talk", "cardiovascular aging interest", "cardiovascular discussion", "catabolism (watch-for)", "celiac adjacency discussion", "cellular NAD+ support", "cellular energy narratives", "cellular senescence research", "chromatin / gene-expression narratives", "chronic bronchitis adjunct talk", "chronic fatigue discussion", "chronic infection discussion", "chronic infection support narratives", "chronic insomnia research history", "circadian / melatonin talk", "circadian / pineal interest", "cognition", "cognition / memory & attention", "cognition / memory talk", "cognition under stress", "collagen / firmness talk", "collagen discussion", "comparison to FLGR-242", "connective-tissue training support", "contest T4+T3 (discussed)", "contest prep (discussed)", "convenience / fewer injections", "cosmetic copper-peptide interest", "cosmetic matrix remodeling", "cosmetic peptide routines", "cramps (watch-for)", "craving reduction (discussed)", "cut (discussed)", "cut-phase conditioning", "cutting / anti-catabolism (discussed)", "cutting phase adjunct (community)", "cytoprotection research (SHLP2/3)", "dandruff / seborrheic dermatitis", "dementia research interest", "depression research discussion", "depression-pipeline talk", "depression-with-insomnia trial talk", "detox discussion", "detoxification capacity narratives", "diabetes-adjacent research interest", "diagnostics adjacency", "diet-switch synergy (animal framing)", "digestive enzyme aging discussion", "dopamine restoration talk", "dry look (discussed)", "dry oral (discussed)", "dryer oral size (discussed)", "dutasteride comparison", "eggs vs a capsule", "endometriosis pipeline (adjacent)", "endurance", "endurance (discussed)", "endurance discussion", "energy", "energy & recovery (community)", "energy / burnout narratives", "energy / fatigue (subjective)", "energy / fatigue discussion", "energy / fatigue talk", "energy / vitality (discussed)", "energy expenditure (discussed)", "energy-drink ingredient literacy", "erections", "estradiol control", "estradiol crash (watch-for)", "estrogen from 19-nor (discussed)", "estrogen metabolism talk", "exercise mimetic narratives", "exercise-mimetic research", "exercise-mimetic research framing", "exercise-mimetic research talk", "exercise\u2013mito peptide discussion", "expensive mild AAS (discussed)", "experimental oncology discussion", "eye health discussion", "fat loss", "fat loss (discussed)", "fat loss / obesity", "fat loss adjacency", "fat loss discussion", "fatty-acid oxidation (discussed)", "fatty-acid oxidation shift (discussed)", "fatty-liver / metabolic discussion", "fertility", "fertility discussion", "fertility/TTC adjacency", "fibromyalgia discussion", "fin/dut side-effect escape", "finasteride non-responder step-up", "finasteride-avoid topical add-on", "fine lines & wrinkles", "fine-line smoothing narratives", "flexibility", "focus", "focus (discussed)", "focus / attention", "focus / memory stack", "focus / word-finding (discussed)", "focus / working memory", "follistatin-class comparison", "food noise reduction", "food noise reduction (discussed)", "food-first polyamine intake optimization", "food-noise reduction (dual pathway)", "forehead & crow's feet appearance", "fracture-risk talk (high-risk spine)", "frailty compression narratives (mouse)", "free testosterone (discussed)", "free testosterone talk (community)", "gallbladder-out digestion", "geroprotection (research framing)", "glabellar / frown-line appearance", "glucose", "glucose / HbA1c adjacency", "glucose / HbA1c control", "glucose / glycemic discussion", "glutathione / antioxidant support", "grain dosing (discussed)", "gray-market identity fights", "gut health", "gut health (discussed)", "gut-mood n=1 logs", "gym pumps", "gyno (discussed)", "gyno last-resort (discussed)", "gyno scare (discussed)", "hair / estrogen-dominance stacks", "hair density narratives", "hardening (discussed)", "healthspan biomarkers (discussed)", "healthy aging / healthspan", "healthy aging biomarker interest", "heart", "heart rate (watch-for)", "heart-risk discussion", "hematopoiesis support (discussed)", "hepcidin / iron regulation", "hormonal acne", "hormone axis", "hormone support", "hormone-axis neighbor stacks", "host-defense peptide research", "hyperphagia control (pathway-specific)", "hypogonadism discussion", "hypogonadotropic hypogonadism induction", "hypothalamic amenorrhea research context", "hypothyroid replacement (discussed)", "immune", "immune / NK-cell adjacency", "immune aging discussion (minority)", "immune modulation", "immune modulation (discussed)", "immune modulation discussion", "infection recovery support (discussed)", "inflammation (discussed)", "inflammation / SASP-burden narratives", "inflammation / mast-cell lore", "inflammation balance (discussed)", "inflammation discussion", "inflammation markers (CRP/IL-6 talk)", "inflammation models (preclinical)", "inflammation moderation (discussed)", "inflammation modulation (double-edged)", "inflammation talk", "inflammation-metabolic research", "injection pain (watch-for)", "injury repair", "injury-adjacent downtime reduction talk", "injury-return training (discussed)", "injury-season recovery adjacency", "insulin sensitivity", "insulin sensitivity (discussed)", "insulin-sensitivity talk", "insurance / prior-auth discussion", "interstitial cystitis (labeled oral)", "jet lag", "joint comfort (discussed)", "joints & tendons", "joints / osteoarthritis discussion", "joints discussion", "leaky-gut / permeability narratives", "leaky-gut forum framing", "lean mass (discussed)", "lean mass preservation", "lean mass preservation (discussed)", "lean mass retention (discussed)", "lean recomp (discussed)", "lean-mass preservation", "libido", "libido (discussed)", "libido (split)", "libido adjacency", "libido and intimacy", "lipid and blood-pressure markers", "lipid markers (preclinical discussion)", "lipid profile (discussed)", "lipids (watch-for)", "lipolysis support (discussed)", "liver (watch-for)", "liver / fatty-liver adjacency", "liver fat discussion", "liver support discussion", "local muscle volume", "local myostatin blockade", "localized growth discussion", "long-COVID stack", "longevity", "longevity (discussed)", "longevity (lifestyle adjacent)", "longevity / SGLT2 talk", "longevity / anti-aging narrative", "longevity / antioxidant talk", "longevity / bioregulator courses", "longevity / cellular energy", "longevity / chromatin-aging interest", "longevity / geroprotection narratives", "longevity / geroprotection talk", "longevity / geroprotector stacks", "longevity / geroscience baseline", "longevity / geroscience discussion", "longevity / healthspan", "longevity / healthspan (discussed)", "longevity / healthspan discussion", "longevity / healthy aging", "longevity / healthy-aging stacks", "longevity / multi-bioregulator calendars", "longevity / musculoskeletal aging", "longevity / organ-bioregulator calendars", "longevity ARB (Attia-adjacent)", "longevity clinic protocols", "longevity discussion", "longevity nootropic", "longevity-adjacent IGF-pathway interest", "losartan comparison", "maculopathy watch-for", "male vitality (discussed)", "mast-cell / histamine folklore", "mast-cell / histamine talk", "memory", "memory & learning (discussed)", "memory (research discussion)", "memory / learning (discussed)", "memory / learning support (discussed)", "men's health discussion", "mental health adjacency", "mental performance under stress", "metabolic / fuel-preference research", "metabolic / redox talk", "metabolic aging interest", "metabolic health", "metabolic health (discussed)", "metabolic markers (discussed)", "metabolic rate (discussed)", "metabolic research", "metabolic syndrome marker interest", "metformin comparison", "methylation / MTHFR folklore", "methylation / homocysteine", "microdose lithium", "microneedling add-on", "mild dry-eye discussion", "min/fin stack staple", "minoxidil stack", "minoxidil-alternative mechanism", "mitochondria", "mitochondrial / energy narratives", "mitochondrial discussion", "mitochondrial function", "mitochondrial function / cytoprotection", "mitochondrial support (discussed)", "mitochondrial uncoupling research tool", "mitophagy / mitochondrial recycling", "mobility", "mobility & morning stiffness (community)", "mobility / flexibility", "mold illness discussion", "mood", "mood (discussed)", "mood (secondary discussion)", "mood / NMDA talk", "mood / affiliative affect", "mood / anhedonia talk", "mood / emotional baseline", "mood / motivation (anecdotal)", "mood / stress (discussed)", "mood / vitality (discussed)", "mood steadiness", "motivation / social", "multiple sclerosis symptom discussion", "muscle", "muscle growth", "muscle growth / hypertrophy (discussed)", "muscle preservation", "muscle soft-tissue", "muscle strain recovery", "muscle-sparing cut talk", "mushroom coffee stacks", "myostatin discussion", "myostatin inhibition", "myostatin inhibition pathway interest", "nails", "nasal tanning spray interest", "needle-averse GLP-1 access interest", "needle-averse GLP-1 access talk", "needle-free peptide interest", "nerve pain experiments", "nerve repair lore (discussed)", "neurogenesis discussion", "neuroimmune regulation (discussed)", "neuropathy discussion", "neuropathy talk", "neuroplasticity discussion", "neuroprotection (discussed)", "neuroprotection (preclinical)", "neuroprotection discussion", "neuroprotection discussion (SHLP2)", "night sweats (watch-for)", "nocturia / overactive-bladder talk", "nocturia talk", "nocturnal GH pulse amplification", "non-GLP hunger talk", "non-injectable Botox-alternative talk", "non-producer food-bypass strategy", "nootropic stacks", "nutrient partitioning (discussed)", "nutrient partitioning discussion", "obesity combination trials", "obesity management research", "obesity research (pipeline comparisons)", "obesity research models", "obesity research tools", "omega-3 index", "oncology adjunct (discussed)", "oral GLP talk", "oral dual-agonist curiosity", "oral vs injection HA", "orexin / DORA comparison", "overactive-bladder talk", "pain discussion", "parathyroid-support narratives", "performance", "performance (resistance training)", "performance / exercise capacity", "performance / strength (discussed)", "performance / training continuity", "performance / training quality", "performance continuity", "performance continuity (cognitive)", "performance continuity (discussed)", "performance continuity while leaning", "photoaging appearance", "photoprotection discussion", "pineal bioregulator interest", "pituitary GH stimulation (discussed)", "pituitary prolactinoma research context", "planned combo with petrelintide", "plaque / CIMT hype", "polycythemia vera talk", "post-AAS HPTA restart talk", "post-AAS recovery narratives", "post-course antiresorptive lock-in", "post-exposure recovery narratives", "post-illness convalescence (discussed)", "post-laser recovery talk", "post-overuse repair", "post-procedure aesthetic recovery", "post-procedure calm-down", "post-procedure recovery talk", "post-stim anhedonia", "post-strain / overuse bounce-back", "post-strain bounce-back", "post-stress heart-support narratives", "post-stroke discussion", "post-surgical soft-tissue talk", "post-viral immune-support talk", "post-workout muscle repair talk", "pre-workout ergogenic interest", "productivity (discussed)", "prolactin discussion", "prolactin-receptor hair (discussed)", "prostate support narratives", "prostate-adjacent urinary flow talk", "pulmonary fibrosis research interest", "pumps (discussed)", "pyrilutamide / RU-58841 comparison", "pyrilutamide comparison", "quality mass (discussed)", "racetam \u201ccholine dump\u201d prevention", "rancid oil watch-for", "rapid size (discussed)", "rapid strength (discussed)", "rare obesity pathway discussion", "recomp", "recomposition", "recomposition (discussed)", "recovery", "recovery (route-debated)", "recovery (secondary discussion)", "recovery / DOMS discussion", "recovery / DOMS talk", "recovery / burnout reset", "recovery / next-day readiness", "recovery / training continuity", "recovery / training continuity (discussed)", "recovery / training readiness", "recovery after hard sessions", "recovery and exercise tolerance", "recovery continuity", "recovery continuity (discussed)", "recovery continuity alongside training", "red blood cells (watch-for)", "renal fibrosis research interest", "research IM peptide", "respiratory / lung-support talk", "respiratory / mucolytic discussion", "respiratory discussion", "reta comparison", "sarcoidosis-associated neuropathic pain", "sarcopenia-adjacent", "satiety / meal-size reduction", "scalp / follicle discussion", "scalp / hair appearance", "scalp mesotherapy", "scar / texture narratives", "scar/fibrosis talk", "seasonal resilience talk", "secondary hypogonadism discussion", "senolytic discussion", "senolytic stack discussion", "sexual function", "sexual function (discussed)", "sexual health", "short run (discussed)", "skin", "skin / recovery adjacency", "skin/hair", "skin/hair (minority discussion)", "skin/hair / photoaging adjacency", "sleep", "sleep (GH-axis adjacency)", "sleep (discussed)", "sleep / Huberman-night add-on", "sleep / Huberman-night stack", "sleep / calm (minority)", "sleep adjacency", "sleep adjacency (discussed)", "sleep balance (discussed; mixed)", "sleep disruption (side)", "sleep onset", "sleep onset / latency", "sleep quality & REM narratives", "sleep quality (mixed reports)", "sleep quality (open-label discussion)", "sleep quality (secondary discussion)", "sleep quality / depth", "sleep quality discussion", "slow vs T3 (discussed)", "slower than Dbol (discussed)", "small fiber neuropathy (SFN)", "social bonding discussion", "soft-tissue", "soft-tissue healing", "soft-tissue healing (route comparison)", "spermatogenesis support", "spine T-score talk", "stimulant-tolerance lore", "strength", "strength & power", "strength continuity (discussed)", "stress", "stress / cortisol (discussed)", "stress load composure (anecdotal)", "strong AI (discussed)", "study / deep-work performance", "suicidal AI (discussed)", "sunless / UV-assisted bronze", "suppression (discussed)", "sustained GH/IGF-1 elevation research", "synaptic plasticity (preclinical)", "synaptogenesis / spinogenesis narrative", "systemic repair narrative", "tanning / pigmentation", "telomerase (hTERT) activation talk", "telomere discussion", "testicular function / anti-atrophy", "testicular volume (with hCG)", "testosterone support (discussed)", "texture & density narratives", "texture & tone narratives", "thyroid replacement (discussed)", "tight junction discussion", "tirzepatide-class dual comparison", "tissue remodeling discussion", "topical anti-androgen DIY", "total testosterone (discussed)", "training recovery continuity", "tremor (watch-for)", "triglycerides", "trunk / midsection aesthetics", "twice-weekly scalp routine talk", "ulcer-adjunct discussion", "urinary calcium conservation (discussed)", "urologic wellness interest (community)", "vaccine response interest", "vascular dementia discussion", "vascular discussion", "vascular encephalopathy support talk", "vascularity (discussed)", "verbal fluency (self-report theme)", "visceral fat (clinical signal)", "visceral fat discussion", "visceral fat reduction (discussed)", "vs ABS-201 (discussed)", "vs Follistatin 344", "vs HMI-115 (discussed)", "vs Nolvadex (discussed)", "vs magnesium glycinate", "vs metformin", "vs psychiatric lithium carbonate", "waist / midsection aesthetics", "waist / visceral-fat talk", "wakefulness", "water (watch-for)", "wearable sleep-score n=1s", "weight management / obesity", "weight management research", "weight management without injections", "wellness-clinic IV lounge culture", "working memory (discussed)", "wound narratives", "wound-adjacent follicle neogenesis talk", "wound/scar remodeling talk", "yearly bioregulator course calendars", "zinc ionophore narrative (community)", "\u201cGLP nausea-lite\u201d amylin story", "\u201cgiga urolithin\u201d talk" ], "delivery_methods": [ "IV", "gene therapy discussion", "implant", "implant (clinical)", "injection", "injection discussion", "intradermal", "intramuscular", "microneedling adjacency", "nasal", "nebulized (discussed)", "oral", "pre-mixed multi-peptide vial", "pulsatile pump (clinical discussion)", "research", "research injection discussion", "research injection in animal work", "research peptide injection discussion", "research routes", "research use discussion only", "separate vials or pre-mixed blend", "subcutaneous", "sublingual", "sublingual (marketed)", "topical", "transdermal (discussed)" ], "types": [ "Peptide", "Non-peptide" ], "reach": [ "Systemic", "Local", "Mixed" ], "popularity": [ "High", "Medium", "Emerging" ], "quick_goals": [ "fat loss", "muscle growth", "recovery", "sleep", "longevity", "cognition", "skin/hair", "libido", "gut health", "performance", "immune", "appetite control", "injury repair", "inflammation", "focus", "mood" ] } }