STUDresearch · Peptide
MID-35
Also known as
MID35 · myostatin inhibitory D-peptide-35 · MIPE-1686 successor · retro-inverso myostatin peptide
Community talk. May be wrong. Not medical advice. Not a protocol. Not for human or animal use.
Peptide
Niche talk
Local
Mouse IM
Growth factors / muscle
Local intramuscular D-peptide in mouse muscle work — not a weekly systemic shop pin.
What people say
MID-35 is a 16-residue retro-inverso myostatin-inhibitory D-peptide. Published work is local mouse IM. It is not FLGR-242.
Doses people talk about
Do not convert mouse IM into FLGR milligrams.
How it may feel
No human feel curve was found.
Published mouse IM researchAmount not reported
Published work is mouse IM. No public human milligrams. Not an FLGR 2.5–5 mg conversion.
Half-life & effect duration
- Half-life in the body
- Half-lifeNo settled estimate
- Felt duration people report
- Felt durationNo human-use timeline reported
Cycles people discuss
Public clocks are mouse research arms, not a vendor peptide block.
Timing
No published half-life; enzyme stability is not a 19-day number.
Stacks
Compared with FLGR-242, not stacked as a kitchen protocol.
Watch for
No human AE table.
Tap a line to jump into the full notes. Research only — may be wrong.
Timing context & sources
Half-life in the body
No published half-life in any species was identified for MID-35.
Enzyme-stability figures and weeks-long mouse muscle change are not a terminal half-life.
Mouse IM remodeling is not human PK.
- Takayama et al. — Development of myostatin inhibitory D-peptides (ACS Med Chem Lett 2022) (opens in a new tab)16-mer retro-inverso MID-35; mouse IM tibialis anterior hypertrophy vs contralateral saline at day 28 in the letter people paste.Mouse IM work, not human PK, safety or felt duration.
Felt duration people report
No human feel curve was identified.
Talk is mouse IM outcomes and FLGR comparisons.
No human self-use reports.
- Takayama et al. — Development of myostatin inhibitory D-peptides (ACS Med Chem Lett 2022) (opens in a new tab)16-mer retro-inverso MID-35; mouse IM tibialis anterior hypertrophy vs contralateral saline at day 28 in the letter people paste.Mouse IM work, not human PK, safety or felt duration.
What people say
- No human diary. forum
- Vs FLGR: one side has papers and no humans; the other has a shop and no papers. That is the comparison, not a winner. forum
- Mouse IM: one tibialis-anterior shot, treated muscle about 133% of the saline side at day 28 in the 2022 letter people paste. animal
- 2026 follow-up: remodeling markers and weight gain on a weeks-long mouse clock, still local. animal
Doses people talk about
- Do not convert mouse IM into FLGR 2.5–5 mg SubQ. forum
- No public human milligrams. forum
- Published in-vivo work is local intramuscular (or iontophoresis in one delivery paper) — no inspected IV/SC human chart. trial
- Framing: Mouse IM research amounts. Not a human ladder. animal
How it may feel
- Now: Comparison object, not a screenshot stack. forum
- If a gray vial appears: there is no copied human fullness diary. forum
- Stop: no human washout lore. forum
- Mouse clock: days to weeks in the injected muscle. animal
Cycles people discuss
- No copied human camp. forum
- Not an FLGR fortnight pin. forum
- Mouse experiments are single-shot or short research arms, not a 12-week vendor block. animal
Timing
- No published half-life in any species in the comparison write-ups people paste. trial
- D-peptide stability in enzyme assays is not a 19-day T½. trial
- Sustained mouse muscle change after one IM shot is remodeling, not proof the peptide persisted for months. animal
More on what it is
- Why people talk about it: 2026 comparison pages set it next to FLGR-242: academic papers vs manufacturer specs; local IM vs systemic albumin story. forum
- Not a human clinic product. forum
- What it is: A 16-mer D-peptide (retro-inverso) from a Tokyo University of Pharmacy myostatin-prodomain program. Name people paste: MID-35. About 2.35 kDa. trial
- How it works (plain): Caps myostatin at the type-I receptor interface instead of wrapping the whole ligand the way follistatin does. trial
- Selectivity is messy in the papers: published numbers also hit GDF-11 / activin A / TGF-β1 in one assay; another paper disputes activin A. trial
Stacks
- Compared with FLGR-242, not stacked. forum
- Not a Wolverine stack ingredient. forum
- Mouse cachexia paper paired it with anamorelin — animal combo, not a gym protocol. animal
Storage notes
- Research chemical / lab reagent talk, not a clinic pen. forum
Watch for
- No human AE table. trial
- Selectivity is not a slogan: published assays are broader than ‘myostatin-only.’ trial
- Local mouse ≠ systemic human. animal
- WADA S4/S0 talk shows up in comparison pages — named follistatin vs un-named 16-mer. trial
Evidence mix
More trial/lab tags than forum tags
Full: every bullet (trial + community). Use Scan for a faster bro-science read.